Tiogamma analogues thiab cov nqi
(lub npe thib ob yog alpha lipoic).
Lub ntsiab ua haujlwm tseem ceeb yog cov antioxidant uas yuav tsum tau los ntawm lub cev rau kev pab tas lub neej.
Kab mob hauv kev tswj hwm tau qhia, dej cawv raug mob ntawm cov hlab ntsha hauv lub cev, mob nyhav ua rau lub cev. Ib qhov nqi ntawm cov kua qaub no hauv lub cev yog tsim tawm ntawm nws tus kheej, tab sis xyoo dhau los, theem ntawm cov khoom lag luam poob qis, thiab qhov kev thov nce ntxiv. Kev ntxiv nrog alpha lipoic acid tuaj yeem kho cov kab mob thiab txhim kho lub neej muaj txiaj ntsig.
Thioctic acid kev npaj muaj nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj, qhov quav qhov quav, ib qho tshuaj tiv thaiv npaj rau kev txhaj tshuaj thiab cov tshuaj muaj zog rau kev npaj daws. Alpha-lipoic acid-based tshuaj yog faib los ntawm cov khw muag tshuaj los ntawm cov tshuaj nkaus xwb.
Thiogamma analogs yog tsim los ntawm cov chaw tsim tshuaj hauv ntau lub teb chaws. Peb sau cov feem ntau hauv peb lub lag luam.
- Ntawv Ntshiab
- Corilip Neo
- Lipoic acid
- Lipothioxone
- Tiolepta.
- 300 (Lub Tebchaws Yelemees),
- Berlition 600 (Lub Tebchaws Yelemees),
- Neyrolipon (Ukraine),
- Thioctacid 600 T (Lub Tebchaws Yelemees),
- Thioctacid BV (Lub Tebchaws Yelemees),
- Espa Lipon (Germany).
Thiogamma lossis Thioctacid?
Thioctacid yog ib qho tshuaj zoo ib yam los ntawm cov tshuaj qub qub.
Lub spectrum ntawm daim ntawv thov ntawm Thioctacid yog tsim nyog:
- kev kho mob ntawm neuropathies,
- daim siab mob
- rog metabolism tsis txaus,
- atherosclerosis,
- qaug cawv,
- metabolic mob.
Tom qab kuaj xyuas tus neeg mob thiab tsim kev kuaj mob tshwj xeeb, tus kws kho mob kos cov caij nyoog rau kev noj cov tshuaj. Raws li txoj cai, kev kho mob pib nrog kev tswj hwm ntawm ampoules ntawm cov tshuaj pharmacological Thioctacid 600 T ntawm 1600 mg rau 14 hnub, tom qab ntawd los ntawm kev tswj hwm qhov ncauj ntawm Thioctacid BV, 1 ntsiav tshuaj ib hnub ua ntej noj mov.
Daim ntawv ntawm BV (tso tawm sai) tuaj yeem hloov cov tshuaj txhaj tshuaj, vim nws tso cai rau kev zom zaub mov ntau ntxiv ntawm cov khoom siv nquag. Lub sijhawm tiv thaiv yog ntev, vim hais tias lub cev yuav tsum tau txais cov tshuaj nquag tsis tu ncua, txhawm rau kom ua haujlwm puv ntoob.
Thioctacid ntsiav tshuaj
Thaum muab cov tshuaj tso ncaj, qhov feem ntawm cov tshuaj nkag mus rau hauv lub cev yog qhov tseem ceeb. Ib qho ampoule yog muab rau 12 feeb, txij li kev pom zoo ntawm kev tswj hwm tshuaj yog 2 ml ib feeb. Thioctic acid reacts rau lub teeb, yog li ampoule tawm ntawm lub pob tsuas ua ntej siv.
Rau kev tswj hwm yooj yim, Thioctacid tuaj yeem siv rau hauv cov ntawv diluted. Rau qhov no, ampoule ntawm cov tshuaj yog yaj hauv 200 ml ntawm physiological saline, tiv thaiv lub raj mis los ntawm tshav ntuj thiab txhaj rau hauv cov hlab ntshav 30 feeb. Thaum tswj hwm kev tiv thaiv kom zoo los ntawm lub hnub ci, dilio Thioctacid khaws cia rau 6 teev.
Kev noj ntau dhau yog pom nrog qhov siab siab ntawm cov tshuaj, ua rau intoxication. Nws yog pov thawj los ntawm xeev ntuav, ntuav, mob taub hau, ntau yam hauv lub cev tsis ua haujlwm syndrome, thrombohemorrhagic syndrome, hemolysis thiab poob siab.
Tau noj ntawm kev kho mob theem yog contraindicated, vim tias nws ua rau muaj tshuaj lom loj heev, qaug dab peg, tsaus muag, thiab muaj peev xwm ua rau neeg tuag taus.
Yog tias pom cov tsos mob no, yuav tsum tau mus pw hauv tsev kho mob thiab ua hauv tsev kho mob kom ua rau detoxification tsim nyog.
Thaum ua kev ua haujlwm ntawm Thioctacid 600 T, qhov tshwm sim tsis zoo tshwm sim thaum siv tshuaj sai sai.
Qhov kev tawm tsam no yuav tshwm sim, tej zaum yog qhov nce ntawm intracranial siab, apnea. Yog hais tias tus neeg mob muaj tus kheej tsis haum rau yeeb tshuaj, tom qab ntawd cov tsos mob ntawm kev ua xua, piv txwv li cov tawv nqaij ua pob khaus, khaus, anaphylaxis, Quincke's edema, yog kev tsis tuaj yeem. Muaj qhov ntxim nyiam ntawm lub ntsej muag platelet tsis zoo, qhov zoo li tshwm sim tam sim ntawd ntshav, tsis pom qhov tsis lo ntawm daim tawv nqaij.
Thaum noj Thioctacid B ntsiav tshuaj, qee zaum cov neeg mob tau cuam tshuam los ntawm kev mob plab zom mov: xeev siab, ntuav, mob plab, ua haujlwm tsis zoo ntawm txoj hnyuv. Vim yog cov cuab yeej ntawm Thioctacid, hlau ions thiab ib leeg ib txoj lw ntsiab nrog ua ke nrog hlau, calcium, magnesium lossis tag nrho cov vitamins-mineral complexes yog contraindicated.
Cov tib neeg uas tab tom noj lossis noj tshuaj kom txo lawv cov ntshav qab zib yuav tsum nco ntsoov tias thioctic acid nce ntxiv ntawm kev siv cov piam thaj, yog li koj yuav tsum ua tib zoo saib xyuas koj qib qab zib thiab kho cov tshuaj qab zib kom tsawg.
Vim tias qhov tshwm sim ntawm sparingly soluble chemical compound, Thioctacid tsis sib xyaw nrog Ringer cov kev daws teeb meem, monosaccharides thiab cov kev daws teeb meem ntawm pawg sulfide.
Piv nrog Tiogamma, Thioctacid muaj ntau dua qhov tsis sib haum, uas suav nrog kev pub mis nkaus xwb, menyuam yaus thiab ib leeg tsis nco qab txog cov feem ntawm cov tshuaj.
Puas muaj dab tsi pheej yig dua thiab zoo dua li Tiogamma? Cov ntsiab lus ntawm analogues thiab sib piv ntawm cov tshuaj. Tiogamma analogues thiab cov nqi
Tiogamma: cov lus qhia rau kev siv thiab tshuaj xyuas
Lub npe Latin: Thiogamma
ATX Code: A16AX01
Cov khoom xyaw nquag: Thioctic acid (Thioctic acid)
Chaw tsim tshuaj paus: Verwag Pharma GmbH & Co. KG (Worwag Pharma GmbH & Co. KG), Beblingen, Lub Tebchaws Yelemees
Hloov kho cov lus piav qhia thiab yees duab: 05/02/2018
Thiogamma yog cov tshuaj uas tswj cov lipid thiab carbohydrate metabolism.
Puas muaj dab tsi pheej yig dua thiab zoo dua li Tiogamma? Cov ntsiab lus ntawm analogues thiab sib piv ntawm cov tshuaj. Kev siv ntau tshaj thiab cov lus qhia tshwj xeeb. Analogs hauv kev muaj pes tsawg leeg thiab qhia txog kev siv
Thiogamma yog ib qho tshuaj tiv thaiv kab mob antioxidant thiab tshuaj metabolic uas ua rau kev hloov pauv ntawm cov carbohydrate thiab lipid.
Cov tshuaj nquag ntawm cov tshuaj yog thioctic (alpha-lipoic) acid. Nws yog ib qho tshuaj antioxidant endogenous uas khi dawb. Thioctic acid yog tsim nyob rau hauv lub cev thaum lub zog oxidative decarboxylation ntawm alpha-keto acids.
Thioctic acid tswj kev ua kom muaj carbohydrate thiab lipid metabolism, txhim kho daim siab ua haujlwm thiab txhawb cov metabolism hauv cov roj cholesterol. Nws muaj cov tshuaj tiv thaiv hypolipidemic, hypoglycemic, hepatoprotective thiab hypocholesterolemic effect. Txhawb nqa cov khoom noj khoom haus zoo ntawm neurons.
Alpha-lipoic acid pab txo cov ntshav qabzib, nce qhov nce ntawm glycogen hauv daim siab thiab kov yeej cov tshuaj insulin. Los ntawm cov txheej txheem ntawm kev nqis tes ua, nws nyob ze rau cov vitamins ntawm pab pawg B.
Cov kev tshawb fawb txog cov nas uas muaj ntshav qab zib streptozotocin-ua rau pom tau tias thioctic acid txo kev tsim cov khoom kawg glycation, txhim kho endoneural ntshav txaus, thiab nce qib ntawm physiological antioxidants xws li glutathione. Cov ntaub ntawv sim ua piv txwv qhia tau tias thioctic acid txhim kho kev ua haujlwm peripheral neuron.
Qhov no siv rau cov kev xav hnov mob hauv kev mob ntshav qab zib, xws li dysesthesia, paresthesia (hlawv, mob, nkag, txo qis rhiab). Cov kev cuam tshuam tau lees paub los ntawm cov neeg kuaj mob ntau yam hauv xyoo 1995.
Cov ntawv tso tawm cov tshuaj:
- Ntsiav tshuaj - 600 mg ntawm cov tshuaj nyob hauv txhua,
- Ib qho kev daws teeb meem rau kev tswj hwm ntawm tsoomfwv ntawm 3%, ampoules ntawm 20 ml (hauv 1 ampoule 600 mg ntawm cov tshuaj yeeb dej caw),
- Thiogamma-turbo - kev daws teeb meem rau cov niam txiv kev ua haujlwm 1.2%, 50 ml vials (hauv 1 lub raj mis 600 mg ntawm cov tshuaj nquag).
Kev ntsuas rau siv
Dab tsi pab Tiogamma? Qhia cov tshuaj hauv cov kis hauv qab no:
- Cov kab mob siab ua rog (rog daim siab ua haujlwm),
- Hyperlipidemia tsis paub meej keeb kwm (cov ntshav muaj roj ntau)
- Daj yuv lom (mob rau daim siab ua paug),
- Daim siab ua haujlwm
- Cawv cawv thiab nws lub txim,
- Kab mob siab ntawm ib yam keeb kwm,
- Kab mob siab
- Cov mob ua paug rau daim siab.
Cov lus qhia rau kev siv Thiogamma, noj ntau npaum li cas
Cov ntsiav tshuaj tau noj ntawm qhov ncauj, ntawm lub plab tas, ntxuav cia nrog kua me me.
Hauv lub xyoo, chav kawm ntawm kev kho tuaj yeem rov ua dua 2-3 zaug.
Cov tshuaj yog muab rau iv hauv ib koob tshuaj 600 mg / hnub (1 amp. Mloog zoo rau kev npaj ntawm kev daws rau Txoj kev lis ntshav ntawm 30 mg / ml lossis 1 lub raj ntawm ib qho kev daws rau infusion ntawm 12 mg / ml).
Thaum ua qhov kev ua haujlwm ntawm qhov mob ntshav, tshuaj yuav tsum tau maj mam muab qeeb, ntawm tus nqi tsis ntau tshaj 50 mg / min (uas yog sib npaug rau 1.7 ml ntawm mloog zoo rau kev npaj ntawm kev daws rau Txoj kev lis ntshav ntawm 30 mg / ml).
Npaj ib qho kev daws teeb meem - cov ntsiab lus ntawm ib lub ampoule ntawm qhov muaj zog yuav tsum tov nrog 50-250 ml ntawm 0.9% sodium chloride tov. Lub raj mis nrog cov tshuaj daws npaj txhij tau nrog cov teeb meem tiv thaiv lub teeb, uas ua tiav nrog cov tshuaj. Cov tshuaj tiav tau tuaj yeem khaws cia rau tsis pub dhau 6 teev.
Yog tias txoj kev daws teeb meem infusion npaj siv, lub raj mis tshuaj tau tawm hauv lub thawv thiab tam sim ntawd npog nrog lub teeb tsom-thaiv. Cov lus qhia yog ua ncaj qha los ntawm lub raj mis, maj mam - ntawm qhov ceev ntawm 1.7 ml / feeb.
Sab sij huam
Thiogamma tej zaum yuav cuam tshuam nrog cov kev mob tshwm sim hauv qab no:
Los ntawm lub plab zom mov: thaum noj tshuaj hauv - dyspepsia (suav nrog xeev siab, ntuav, kub siab).
- Los ntawm sab ntawm lub hauv nruab nrab cov hlab ntsha hauv lub cev: tsis tshua muaj (tom qab iv kev tswj hwm) - kev nrhav, daim ntawv pov thawj kawm tiav, nrog kev tswj hwm sai - nce siab intracranial siab (qhov pom ntawm lub siab ntawm qhov hnyav ntawm lub taub hau).
- Los ntawm cov ntshav kev sib xyaw ua ke: tsis tshua muaj (tom qab kev tswj hwm iv) - taw qhia cov ntshav hauv cov leeg nqaij, daim tawv nqaij, thrombocytopenia, hemorrhagic pob (purpura), thrombophlebitis.
- Los ntawm lub tshuab ua pa: nrog ceev ntawm / hauv kev qhia, ua pa nyuaj tau.
- Ua xua: urticaria, mauj tshuaj tiv thaiv (nce mus rau hauv kev nthuav dav ntawm anaphylactic kev poob siab).
- Lwm tus: hypoglycemia tuaj yeem tsim muaj (vim tias txhim kho cov piam thaj hauv siab).
Cov Yuav Tsum Muaj
Thiogamma yog contraindicated nyob rau hauv cov nram no:
- cov menyuam yaus thiab cov tub ntxhais hluas hnub nyoog qis dua 18 xyoo,
- cev xeeb tub lub sij hawm
- lactation lub sijhawm
- piam thaj-galactose malabsorption, lactase deficiency, cov roj ntsha tsis sib haum (rau cov ntsiav tshuaj),
- hypersensitivity rau lub ntsiab los yog txhawb cov tshuaj ntawm cov tshuaj.
Tawm tsam keeb kwm yav dhau los ntawm kev siv yeeb tshuaj, dej cawv tsis tuaj yeem nqa, txij li nyob rau hauv kev cuam tshuam ntawm ethanol, qhov ntxim nyiam ntawm kev tsim muaj mob hnyav los ntawm cov leeg hlwb thiab cov hnyuv nce ntxiv.
Cov nqi hauv Moscow cov chaw muag tshuaj: Thiogamma daws 12 mg / ml 50 ml - los ntawm 197 txog 209 rubles. 600 mg ntsiav tshuaj 30 pcs. - los ntawm 793 txog 863 rubles.
Khaws tawm ntawm qhov ncav cuag cov menyuam yaus, tiv thaiv los ntawm lub teeb, ntawm qhov kub txog li 25 ° C. Txee lub neej yog 5 xyoos. Hauv cov tsev muag tshuaj, muaj cov tshuaj noj.
Cov yeeb yaj kiab sib piv ntawm cov tshuaj thiogamma raug nthuav tawm, raws li cov ntsiab lus kho mob, hu ua "txhais tau zoo" - cov tshuaj sib hloov uas muaj ib lossis ntau ntawm tib cov tshuaj nquag los ntawm lawv cov cuam tshuam rau lub cev. Thaum xaiv cov lus txhais, xav txog tsis yog lawv cov nqi nkaus xwb, tab sis kuj yog lub teb chaws ntawm kev tsim khoom thiab lub koob npe ntawm cov neeg tsim khoom.
Qhia txog ntawm cov tshuaj
Raws li coenzyme ntawm mitochondrial multienzyme complexes, nws koom nrog oxidative decarboxylation ntawm pyruvic acid thiab alpha-keto acids. Nws pab txhawm rau txo cov kev kub siab ntawm cov piam thaj hauv cov ntshav thiab nce cov ntsiab lus glycogen hauv lub siab, ntxiv rau kov yeej cov tshuaj insulin.
Koom nrog cov kev cai ntawm lipid thiab carbohydrate metabolism, cuam tshuam cov roj metabolism hauv lub cev, txhim kho daim siab ua haujlwm, muaj kev cuam tshuam hauv kev cuam tshuam txog thaum muaj tshuaj lom nrog ntsev hlau hnyav thiab lwm yam ua rau qaug. Nws muaj cov kab mob hepatoprotective, hypolipidemic, hypocholesterolemic thiab hypoglycemic teebmeem. Txhim kho trophic neurons.
Ntawm cov ntshav qab zib mellitus, thioctic acid txhim kho endoneural ntshav txaus, nce cov ntsiab lus ntawm glutathione mus rau lub cev muaj txiaj ntsig, uas ua rau muaj kev txhim kho hauv lub xeev ua haujlwm ntawm peripheral cov leeg hauv cov ntshav qab zib polyneuropathy.
Sau cov analogues
Ua tib zoo mloog! Daim ntawv teev npe muaj cov lus txhais ntawm Tiogamma, uas muaj cov qauv sib thooj, yog li koj tuaj yeem xaiv qhov hloov pauv koj tus kheej, noj mus rau hauv daim ntawv sau thiab ntau npaum li cas ntawm cov tshuaj uas kws kho mob tau sau tseg. Muab kev nyiam rau cov tuam ntxhab los ntawm Asmeskas, Nyiv, Western Europe, thiab cov tuam txhab lag luam zoo los ntawm Eastern Europe: Krka, Gideon Richter, Actavis, Aegis, Lek, Hexal, Teva, Zentiva.
Daim ntawv tso tawm (los ntawm qhov nrov) | Nqe, tshiav. |
Tiogamma | |
P - p rau Txoj kev lis ntshav 12 mg / ml 50 ml fl N1. (Solufarm GmbH & Co.KG (Lub Teb Chaws Yelemees) | 219.60 |
P - r d / inf 12mg / ml 50ml fl No. 1 (Solufarm GmbH thiab Co.KG (Lub Tebchaws Yelemees)) | 230.50 |
Tab 600mg N30 (Artezan Pharma GmbH & Co.KG (Lub Teb Chaws Yelemees) | 996.20 |
600mg Tsis Yog. 30 tab p / o (Dragenofarm Apotheker Puschl GmbH (Lub Tebchaws Yelemees) | 1014.10 |
Tshuaj rau infusions 12mg / ml 50ml fl N1 (Solufarm GmbH thiab Co.KG (Lub Tebchaws Yelemees) | 2087.80 |
Alpha lipoic kua qaub | |
ANTI - HNUB NYOOG 100 MG tshuaj ntsiav, 30 pcs. | 293 |
Alpha-Lipoic Acid | |
Cwj Pwm | |
Berlition 300 | |
Ampoules 300 mg, 12 ml, 5 pcs. | 497 |
Qhov ncauj, ntsiav tshuaj 300 mg, 30 pcs. | 742 |
Berlition 600 | |
Ampoules 600 mg, 24 ml, 5 pcs. | 776 |
Lipamide | |
Coated Lipamide ntsiav tshuaj, 0.025 g | |
Lipoic acid | |
Lipoic acid | |
30mg Tsis Yog. 30 tab p / o Kvadrat - S (Kvadrat - S OOO (Russia) | 79 |
Lipoic Acid Coated ntsiav tshuaj | |
Lipothioxone | |
Neuro lipone | |
300mg No. 30 lub kaus mom (Farmak OAO (Ukraine) | 252.40 |
Oktolipen | |
300mg lub kaus N30 (Pharmstandard - Leksredstva OAO (Russia) | 379.70 |
30mg / ml amp 10ml N10 (Pharmstandard - UfaVITA OJSC (Russia) | 455.50 |
30mg / ml 10ml Tsis tau. 10 feeb kom meej rau kev npaj ntawm kev daws rau infusion (Pharmstandard - Ufa vit.z - d (Russia) | 462 |
600mg No. 30 tab (Pharmstandard - Tomskkhimfarm OJSC (Russia) | 860.30 |
Xwm | |
Thioctacid 600 | |
Thioctacid 600 T | |
Ampoules 600 mg, 24 ml, 5 pcs. | 1451 |
Thioctacid BV | |
600 mg ntsiav tshuaj, 100 pcs. | 2928 |
Thioctic acid | |
Thioctic acid | |
Thioctic Acid-Vial | |
Tiolepta | |
Tab 300mg N30 (Canonfarm Ntau Lawm CJSC (Russia) | 393.60 |
Tab p / pl. Txog 600mg N60 (Canonfarm Ntau Lawm CJSC (Russia) | 1440.10 |
Thiolipone | |
Ntsiav tshuaj coated zaj duab xis 300 mg, 30 pcs. | 300 |
Ampoules 300 mg, 10 ml, 10 pcs. | 383 |
Ntsiav tshuaj coated zaj duab xis 600 mg, 30 pcs. | 641 |
Es Lias lipon | |
600mg No. 30 tab (Pharma Wernigerode GmbH (Lub Teb Chaws Yelemees) | 694.10 |
600 mg / 24 ml amp N1 (ESPARMA GmbH (Lub Tebchaws Yelemees) | 855.40 |
600 mg / 24 ml amp N5 (ESPARMA GmbH (Lub Tebchaws Yelemees) | 855.70 |
28 cov qhua tau qhia txog kev nkag noj txhua hnub
Kuv yuav tsum noj Thiogamma ntau npaum li cas?
Cov neeg teb feem ntau yuav tau haus cov tshuaj no 1 zaug nyob rau ib hnub. Daim ntawv tshaj tawm qhia tias pes tsawg tus neeg teb ntxiv siv cov tshuaj no.
Cov Tswv Cuab | % | |
---|---|---|
Ib hnub | 22 | 78.6% |
2 zaug ib hnub | 5 | 17.9% |
3 zaug ib hnub | 1 | 3.6% |
33 tus qhua tau tshaj tawm qhia tias noj ntau npaum li cas
Cov Tswv Cuab | % | |
---|---|---|
501mg-1g | 15 | 45.5% |
11-50mg | 6 | 18.2% |
201-500mg | 5 | 15.2% |
6-10mg | 3 | 9.1% |
51-100mg | 2 | 6.1% |
101-200mg | 1 | 3.0% |
1-5mg | 1 | 3.0% |
Tsib tus neeg qhua tau tshaj tawm hnub tas sijhawm
Ntev npaum li cas nws siv sij hawm Thiogamma hnov zoo txog kev txhim kho hauv tus neeg mob lub sijhawm?
Cov neeg tuaj koom kev soj ntsuam feem ntau tom qab 1 lub hlis hnov zoo dua. Tab sis qhov no yuav tsis raug rau lub sijhawm uas koj yuav txhim kho. Nrog koj tus kws kho mob xav ntev li cas koj yuav tsum tau noj cov tshuaj no. Cov lus hauv qab no qhia cov kev tshwm sim ntawm kev tshawb fawb txog kev pib ua haujlwm zoo.
Cov Tswv Cuab | % | |
---|---|---|
1 hlis | 2 | 40.0% |
> 3 hlis | 2 | 40.0% |
1 hnub | 1 | 20.0% |
Yim tus qhua tuaj xyuas lub sijhawm txais tos
Lub sijhawm twg zoo tshaj los noj Tiogamma: ntawm lub plab khoob, ua ntej, tom qab, lossis nrog zaub mov noj?
Cov neeg siv Website feem ntau qhia txog cov tshuaj no rau ntawm lub plab tas. Txawm li cas los xij, tus kws kho mob yuav qhia lwm lub sijhawm. Daim ntawv tshaj tawm qhia tias thaum tus neeg mob xam phaj tas cov tshuaj noj.
Cov Hnub So Haujlwm
Cov ntaub ntawv ntawm nplooj ntawv tau txheeb xyuas qhov tseeb los ntawm kws kho mob Vasilieva E.I.
Thiogamma yog txhais tau tias ntawm kev tswj hwm kev ua kom muaj cov roj carbohydrate thiab lipid metabolism. Qhia cov tshuaj no rau cov ntshav qab zib. Cov nkauj muaj xws li thioctic acid. Muaj cov qauv hauv cov ntsiav tshuaj, tsom rau kev daws teeb meem thiab cov kev daws teeb meem lawv tus kheej. Cov tshuaj raug faib nrog cov tshuaj noj.Xav txog qhov ntsuas tseem ceeb, nrog rau thiogamma, cov lus qhia rau kev siv, nqi, tshuaj xyuas, analogues.
Ntshav qab zib polyneuropathy
Cov lus qhia rau kev siv Tiogamma 600 yog mob ntshav qab zib mob polyneuropathy. Nws mob rau cov neeg muaj ntshav qab zib. Nws kuj tseem tuaj yeem tshwm sim ua ntej kev txhim kho kabmob. Nws ua tau nws tus kheej raws li kev hloov pauv ntawm cov hlab ntsha hauv lub siab, qhov sib txawv ntawm qhov txawv thiab qhov muaj zog, qhov hnov zoo li mob, txhaws thoob plaws lub cev, tab sis feem ntau feem ntau rau ob txhais ceg.
Cov tshuaj raug tswj kom tshem tawm cov tsos mob, txhim kho qhov rhiab ntawm cov hlab ntaws, thiab tseem tiv thaiv kev txhim kho ntawm cov teeb meem, nrog rau mob txhab.
Cov kws kho mob hais li cas txog pob yas
Tus kws kho mob ntawm Medical Sciences, Kws phais neeg yas Morozov EA:
Kuv tau koom nrog hauv kev phais yas ntau xyoo. Muaj ntau tus neeg nto moo leej twg xav mus saib yau dhau los dhau ntawm kuv. Tam sim no, phais yas yog poob nws qhov tseeb vim tias kev kawm txuj ci tsis sawv ntsug, ntau thiab ntau qhov tshiab rau kev rov ua kom lub cev rov tshwm, thiab qee qhov kev qhia tau zoo heev. Yog tias koj tsis xav tau lossis tsis muaj sijhawm los txiav txim siab txog kev phais yas, Kuv yuav pom zoo kom muaj kev sib txig sib luag, tab sis tus nqi qis dua lwm qhov zoo li sai tau.
Rau ntau tshaj li 1 xyoos tam sim no, cov tshuaj zoo heev rau cov tawv nqaij rov ua dua tshiab NOVASKIN, uas tuaj yeem tau txais, tau dhau ntawm European cov lag luam PUB DAWB Cov. Hais txog qhov ua tau zoo, nws yog ob peb zaug zoo tshaj rau Botox txhaj, kom tsis txhob hais txog txhua yam ntawm cream. Nws yog qhov yooj yim siv thiab nws qhov tseem ceeb tshaj plaws koj yuav pom tam sim ntawd. Yog tsis muaj exaggeration, Kuv yuav hais tias me me thiab sib sib zog nqus wrinkles, hnab hauv qab qhov muag dhau yuav luag tam sim ntawd. Ua tsaug rau qhov pom tseeb ntawm daim tawv nqaij, daim tawv nqaij tau thim rov qab los ua dua tshiab, tsim dua tshiab, qhov hloov tsuas yog xim tshwj xeeb xwb.
Cov ua rau ntawm tus kab mob yog suav tias yog mob los ntawm kev kho mob ntshav qab zib. Hauv particular:
- Ntshav qab zib cov ntshav muaj ntshav ua rau muaj kev kub ntxhov nyob thoob plaws lub cev,
- Khoom noj khoom haus tsis muaj zog, hypoxia,
- Ntxim tsis nqus ntawm cov as-ham thiab cov vitamins,
- Nquag decompensation ntawm cov ntshav qab zib.
Nrog rau kev txhim kho ntshav qab zib, polyneuropathy yog tsau thiab thaum kawg tuaj yeem hloov kho tsis tau. Muaj ob peb theem ntawm tus kabmob no: subclinical, kuaj mob.
Ntawm qhov subclinical, uas yog thawj theem, feem ntau tshwj xeeb tshaj yog tsis pom cov tsos mob - tsuas yog tsis tshua muaj loog.
Ntawm theem ob, chaw soj ntsuam, ntau yam tsos mob twb tshwm sim raws li daim ntawv ntawm tus kab mob - mob hnyav, mob ntev, tsis mob, amyotrophic.
Hauv theem peb, kev nyuaj tshwm sim twb tau tsim kho. Ib qho ntawm lawv yog mob rau hauv sab ceg qis. Hauv 15% ntawm cov neeg mob, cov cheeb tsam cuam tshuam yuav tsum tau muab tshem tawm, uas yog, txiav tes haujlwm yog ua tiav. Polyneuropathy yog kho nrog ntau cov tshuaj, suav nrog:
- Cov vitamins
- Alpho-Lipolic Acid,
- Aldose reductase inhibitors,
- Tshuaj kho mob
- Actovegin,
- Tshuaj tua kab mob (yog tias muaj ib tus kab mob sib kis)
- Kev npaj calcium thiab potassium.
Pharmacokinetics thiab kev txiav txim ntawm pharmacological
Qhov no yog ib tus neeg sawv cev khoom noj metabolic uas muaj cov tshuaj tua kab mob endogenous uas khi cov dawb. Nrog nws cov kev pab, cov khoom tsim nyog thiab cov acids yog synthesized hauv tus neeg mob lub cev. Nws kuj ua haujlwm xws li coenzyme, koom nrog hauv kev ua haujlwm oxidative. Pab txo cov ntshav piam thaj thiab nce qib glycogen hauv nplooj siab. Nrog nws cov kev pab, nws muaj peev xwm kom kov yeej cov tshuaj insulin.
Thioctic acid nyob rau hauv Thiogamma yog qhov zoo sib xws hauv biochemistry rau cov vitamins B. Lawv pab koom rau hauv cov carbohydrate thiab lipid metabolism, txhawb cov metabolism hauv roj, thiab txhim kho daim siab ua haujlwm. Yog li, muaj kev tiv thaiv lub siab ua haujlwm rau lub siab, nrog rau kev tiv thaiv hypoglycemic, hypocholesterolemic thiab hypolipidemic teebmeem. Hauv neurons, trophism txhim kho. Tshaj tawm tus nqi, cov lus qhia rau kev siv, Thiogamma hauv kev daws teebmeem rau iv yuav pab txo qis phiv thiab mob hnyav pab txhim kho kev noj qab haus huv.
Tom qab noj cov tshuaj Tiogamma, thioctic acid yuav luag tag thiab nqus tau los ntawm txoj hnyuv. Yog tias koj noj ib ntsiav tshuaj tib lub sijhawm nrog zaub mov, tom qab ntawd cov txheej txheem kev nqus yog txo qis, siv sijhawm ntev li ib teev. Ntxiv mus, kev lag luam xyoob ntoo yog 30%. Nrog kev txhaj tshuaj rau hauv cov leeg, Thiogamma, raws li kws kho mob, tau nqus tag nrho hauv 10-11 feeb.
Cov tshuaj undergoes thawj-dhau kev ua hauj lwm, tsim cov metabolites. Lawv dhau los ntawm lub raum los ntawm 90%. Ib nrab-lub neej yog 20-50 feeb, nyob ntawm tus yam ntxwv ntawm tus neeg mob lub cev.
Thov
Cov tshuaj yog muab qhov ncauj ntawm 300-600 mg ib hnub ib zaug. Cov ntsiav tshuaj tau noj yam tsis muaj kev zom nrog me me ntawm cov dej. Cov tshuaj yog muab tshuaj rau hauv qhov nyiaj ntawm 600 mg. Thaum nyuam qhuav pib ntawm kev kho mob, tso ntshav tshuaj ntawm cov tshuaj yog kev pom zoo. nqa tawm txhua hnub rau 2-4 lub lim tiam, nyob ntawm qhov ntsuas thiab siv tshuaj ntawm tus kws kho mob. Tom qab cov tshuaj tau muab cov tshuaj ntawm qhov ncauj ntawm Tiogamma ntsiav tshuaj hauv qhov ntau npaum li ntawm 300-600 mg. Thaum cov tshuaj tau muab tshuaj rau txoj leeg, nws yog ib qhov tsim nyog los ua cov txheej txheem kom qeeb li sai tau - 50 mg / min.
Raws li cov lus qhia Thiogamma Turbo raug tswj hwm niam txiv yog tias daws tau.
Thov siv rau hauv rooj plaub uas qhov kev ua txhaum ntawm kev rhiab heev uas twb hais tawm thiab cuam tshuam nrog kev mob ntshav qab zib puv neuropathy.
Thaum cov concentrate tau tov nrog cov kuab tshuaj, tus neeg saib xyuas tau muab tshuaj rau tam sim ntawd kom nws cov hauj lwm zoo. Nco ntsoov tias tiv thaiv kev daws los ntawm hnub ci.
Hauv cov qauv tshuaj, cov tshuaj yog siv raws li kws kho mob sau tseg, feem ntau tom qab infusion. Lub sijhawm tiv thaiv yog 1-4 hlis. Cov lus qhia rau kev siv Thiogamma hais tias cov tshuaj muaj peev xwm noj tsis hais txog khoom noj dab tsi, tab sis nrog zaub mov noj, cov txheej txheem nqus tau tsawg, raws li tau hais los saum no.
Yog li, kev sab laj nrog tus kws kho mob mus kawm yog qhov tsim nyog ntawm cov ncauj lus no.
Kev npaj thiab kev coj ntawm qhov kev daws teeb meem
Txhawm rau npaj cov tshuaj Thiogamma rau kev tswj hwm, 1 ampoule ntawm cov tshuaj hauv 20 ml (sib npaug rau 600 mg ntawm thioctic acid) yog sib xyaw nrog 50-250 ml ntawm 0.9% sodium chloride tov. Nws yog muab raws li kev lis ntshav thaum lub sijhawm 20-30 feeb. Lawv tau tsim los ntawm cov fwj tshwj xeeb tso rau hauv lub teeb-tiv thaiv teeb meem dai nrog cov tshuaj (lawv yog cov xim dub thiab ua los ntawm cov polyethylene tshwj xeeb).
Yog tias infusions tau tsim los ntawm 50 ml vials, tom qab ntawd cov txheej txheem tau pom ncaj qha los ntawm lub raj mis uas kev daws teeb meem nyob. Nws tseem yuav tsum muab tso rau hauv cov ntaub ntawv tiv thaiv tshwj xeeb uas ua los ntawm dub polyethylene.
Sab sij huam
Cov kev mob tshwm sim tom qab siv cov tshuaj yog tseem muaj. Muaj cov uas dhau ntawm lawv tus kheej thiab coj tej kev ntsuas los tshem tawm lawv yog nyob ntawm xaiv:
- Lub plab zom mov: kub siab, ntuav, xeev siab - uas yog, dyspepsia,
- CNS: daim ntawv pov thawj tsis txaus ntseeg, kev ua kom tawv ncauj, thiab nrog rau kev tswj hwm sai ntawm cov tshuaj quav tshuaj - nce siab, zoo nkaus li hnyav hauv taub hau,
- Hematopoietic system: pom qhov hemorrhages rau ntawm cov qog ua kua, hemorrhagic pob, thrombocytopenia thiab thrombophlebitis,
- Kev ua pa rov tuaj: nrog kev tswj hwm sai - ua pa nyuaj.
Tab sis muaj teeb meem nyob rau hauv uas yuav tau txais kev pab hnyav. Piv txwv li, tus neeg mob tuaj yeem mob qog ntshav qis vim qhov nce ntxiv ntawm qhov nqus ntawm cov piam thaj, nrog rau kev ua xua rau txog kev poob siab anaphylactic.
Muaj tsis ntau contraindications rau Thiogamma hauv ntsiav tshuaj los yog tshuaj. Yeej, cov no yog cov yam ntxwv ntawm tib neeg lub cev hauv qee lub sijhawm ntawm lub neej:
- Lactation
- Cev xeeb tub
- Cov me nyuam lub hnub nyoog
- Kev ua haujlwm tsis zoo.
Kev siv ntawm cov tshuaj Tiogamma kuj tseem tsis zoo rau tib neeg kev txom nyem los ntawm:
- Los ntawm lactate cidosis (thiab txawm tias tsis muaj ib qho, tab sis nws yog ib qho yooj yim kev npau taws),
- Hauv kev ua txhaum loj ntawm daim siab thiab lub raum, uas cov txheej txheem thiab tshem tawm cov tshuaj,
- Myocardial infarction, uas yog nyob rau hauv ib qho kev mob tshwm sim (cov kev mob tshwm sim loj heev yuav tshwm sim vim lub cev tsis muaj zog),
- Decompensated hlab plawv lossis ua pa tsis ua haujlwm,
- Hauv cov cawv quav cawv,
- Lub cev qhuav dej
- Mob kev puas hlwb nyob rau hauv cov ntshav ncig hauv cheeb tsam lub hlwb (vim tias muaj kev pheej hmoo ntawm phiv nyob rau hauv daim ntawv ntawm intracranial siab).
Hais txog kev ua menyuam yaus, nws tsim nyog kom paub meej tias tsis muaj kev tiv thaiv kabmob tshwj xeeb, tsuas muaj tsis tau kawm txog hom neeg no.
Thiogamma rau lub ntsej muag
Paradoxically, tab sis xws li ib qho kev kho mob hnyav raws li thiogamma rau lub ntsej muag, raws li kev xav ntawm cosmetologist, tseem tuaj yeem siv tau. Raws li lawv, qhov no yog qhov zoo tshaj plaws tshuaj tiv thaiv wrinkle uas yuav pab koj sai sai rejuvenate.
Alpho-lipolic acid pab ua rau cov laus qeeb qeeb, tshem tawm pob, ua rau daim tawv nqaij, rov ua kom tawv nqaij, nqig o, txo qhov pores thiab lwm yam.
Thiogamma rau lub ntsej muag yog siv los ua cov qauv ntws, txiav txim los ntawm cov neeg siv khoom saib xyuas, thiab sab nraud. Txoj kev yooj yim tshaj plaws yog thov rau daim tawv nqaij nrog paj rwb qhwv. Chav kawm yog 10 hnub, thiab cov txheej txheem yog nqa tawm txhua hnub.
Qee tus neeg pom zoo ua cov txheej txheem ib hnub ob zaug, tab sis kev siv cov tshuaj tsis raug muab, thiab yog li nws tsuas yog tsis yooj yim sua kom twv seb kev tawm tsam ntawm lub cev. Feem ntau, thiogamma rau lub ntsej muag tau txais kev soj ntsuam zoo. Tab sis muaj cov neeg siv network uas tau lees tias lawv feem ntau tsim kev phiv los ntawm kev ua xua - tshwj xeeb, urticaria thiab txawm tias anaphylactic poob siab. Yog li ntawd, qhov cuab yeej tsis pom zoo rau cov laj thawj no.
Cov tshuaj txiav txim hlau. Thioctic (lip-lipoic) acid, ib qho kev tiv thaiv kabmob (khi dawb radicals), yog tsim hauv lub cev los ntawm oxidative decarboxylation ntawm alpha-keto acids. Raws li coenzyme ntawm mitochondrial multienzyme complexes, nws koom nrog oxidative decarboxylation ntawm pyruvic acid thiab alpha-keto acids. Nws pab txhawm rau txo cov kev kub siab ntawm cov piam thaj hauv cov ntshav thiab nce cov ntsiab lus glycogen hauv lub siab, ntxiv rau kov yeej cov tshuaj insulin.
Koom nrog cov kev cai ntawm lipid thiab carbohydrate metabolism, cuam tshuam cov roj metabolism hauv lub cev, txhim kho daim siab ua haujlwm, muaj kev cuam tshuam hauv kev cuam tshuam txog thaum muaj tshuaj lom nrog ntsev hlau hnyav thiab lwm yam ua rau qaug. Nws muaj cov kab mob hepatoprotective, hypolipidemic, hypocholesterolemic thiab hypoglycemic teebmeem. Txhim kho trophic neurons.
Ntawm cov ntshav qab zib mellitus, thioctic acid txhim kho endoneural ntshav txaus, nce cov ntsiab lus ntawm glutathione mus rau lub cev muaj txiaj ntsig, uas ua rau muaj kev txhim kho hauv lub xeev ua haujlwm ntawm peripheral cov leeg hauv cov ntshav qab zib polyneuropathy.
Tom qab kev tswj hwm ntawm qhov ncauj, thioctic acid sai sai thiab yuav luag nqus los ntawm cov hnyuv. Thaum noj nrog zaub mov, kev nqus poob qis. Lub sijhawm kom ncav cuag C max (4 μg / ml) yog li 30 feeb. Bioavailability - 30-60% vim los ntawm qhov tshwm sim ntawm "thawj kev tso cai" los ntawm daim siab.
Nws yog metabolized hauv daim siab los ntawm sab saw oxidation thiab kev sib txuas.
Thioctic acid thiab nws cov metabolites yog ua rau lub raum tso tawm (80-90%), hauv ib qho me me - tsis hloov pauv. T 1/2 yog 25 min.
Muab tso rau hauv 600 mg (1 tab.) 1 lub sijhawm / hnub.
Cov ntsiav tshuaj tau noj ntawm lub plab khoob, tsis tas yuav zom, nrog me me ntawm cov kua.
Lub sijhawm kho yog 30-60 hnub, nyob ntawm seb tus mob hnyav npaum li cas. Ua tau rov ua dua qhov tseeb ntawm txoj kev kho mob 2-3 zaug hauv ib xyoos.
Qhov tshwm sim ntawm qhov tshwm sim tsis zoo yog muab raws li WHO kev faib tawm:
Pharmacological kev txiav txim
Thioctic acid (alpha lipoic acid) - ib qho kev tiv thaiv tsis zoo (khi dawb radicals), yog tsim nyob rau hauv lub cev los ntawm oxidative decarboxylation ntawm alpha ketoxylate. Raws li coenzyme ntawm mitochondrial multienzyme complexes, nws koom nrog oxidative decarboxylation ntawm pyruvic acid thiab alpha-keto acids.
Nws pab txhawm rau txo qis kev mloog ntawm cov piam thaj hauv cov ntshav thiab nce glycogen hauv lub siab, ntxiv rau kov yeej cov tshuaj insulin. Qhov xwm ntawm qhov biochemical txiav txim yog ze rau ntawm cov vitamins B.
Koom nrog cov kev cai ntawm lipid thiab carbohydrate metabolism, txhawb cov metabolism hauv roj, txhim kho daim siab ua haujlwm. Nws muaj cov kab mob hepatoprotective, hypolipidemic, hypocholesterolemic, hypoglycemic effect. Txhim kho trophic neurons.
Kev siv trometamol ntsev ntawm thioctic acid hauv kev daws rau kev tswj hwm iv (muaj qhov tsis haum nruab nrab) tuaj yeem txo qhov hnyav ntawm qhov tshwm sim tsis zoo.
Sab sij huam
Kev tsis haum tshuaj (urticaria, pruritus, anaphylactic shock). Xeev siab thiab kub siab (thaum noj ntawm qhov ncauj, ntau tsawg dua thaum siv trometamol ntsev).
Nrog kev tswj hwm mob ntshav-taw tes rau hauv cov leeg hauv lub cev, daim tawv nqaij, thrombocytopathy, hemorrhagic pob (purpura), mob thrombophlebitis, muaj zog intracranial siab (tswj hwm ceev ceev), ua pa nyuaj, ntshav qab zib ntshav siab (vim tias txhim kho cov ntshav qab zib), ua kom mob, ua kom tsis nco qab, ua kom tsis muaj zog ntshav siab
Thiogamma lossis Berlition?
Tus tsim cov khw muag khoom tso npe tau sau npe nyob hauv lub teb chaws Yelemees, cov tshuaj muaj txiaj ntsig tau yuav hauv Suav teb. Muaj kev nkag siab yuam kev tias Berlition muaj txiaj ntsig ntau dua nyiaj txiag, tab sis qhov no tsis muaj tseeb.
Berlition ampoules
Daim ntawv ntawm kev tso tawm yog ampoules thiab cov ntsiav tshuaj nrog kev siv tshuaj ntau npaum li 300 mg, tus naj npawb ntawm cov ntsiav tshuaj hauv pob muaj ntau me, uas txhais tau tias koj yuav tsum siv qhov kev coj ua ob npaug ntawm cov tshuaj kom tau txais kev kho mob ib hnub ntawm alpha-lipoic acid. Yog li ntawd, tus nqi ntawm chav kawm nce.
Thiogamma lossis Oktolipen?
Ib qho analogue ntawm Lavxias ntau lawm ntawm tus nqi txaus siab rau ntim. Tab sis thaum suav tus nqi ntawm chav kawm, nws pom tseeb tias tus nqi kho yog nyob rau theem ntawm kev siv nyiaj ntau dua.
Cov uas muaj Oktolipen ntau me dua, vim nws tsuas muaj ob qhov ntsuas rau sau tseg - mob ntshav qab zib thiab haus dej haus cawv polyneuropathy.
Los ntawm cov cuab yeej biochemical zoo ib yam li cov vitamins ntawm pab pawg B.
Tso tawm daim ntawv thiab muaj pes tsawg leeg
- daws rau Txoj kev lis ntshav: pob tshab, lub teeb daj daj lossis daj ntsuab (50 ml hauv lub khob tsaus nti, 1 lossis 10 lub khob hauv lub thawv ntawv thawv),
- mloog zoo rau kev daws teeb meem rau kev lis ntshav: ib qho tseeb ntawm cov xim daj-ntsuab (20 ml hauv ampoule iav tsaus, 5 ampoules hauv lub tais, 1, 2 lossis 4 pallets hauv daim ntawv thawv),,
- cov ntsiav tshuaj coated: oblong, convex ntawm ob sab, lub teeb daj hauv xim nrog dawb thiab daj suav ntawm kev sib txawv, nrog kev pheej hmoo ntawm ob sab, lub teeb daj tseem ceeb yog pom nyob rau hauv ntu ntu (10 pcs. hauv blister, 3, 6 lossis 10 lub hlwv hauv pob ntawv khaws cia).
Cov tshuaj nquag yog thioctic acid:
- 1 ml ntawm kev daws - 12 mg (600 mg hauv 1 lub raj mis),
- 1 ml ntawm mloog zoo - 30 mg (600 mg hauv 1 ampoule),
- 1 ntsiav tshuaj - 600 mg.
- kev daws: macrogol 300, meglumine, dej rau kev txhaj tshuaj,
- mloog zoo: macrogol 300, meglumine, dej rau kev txhaj tshuaj,
- ntsiav tshuaj: colloidal silicon dioxide, croscarmellose sodium, microcrystalline cellulose, simethicone (dimethicone thiab colloidal silicon dioxide nyob rau hauv ib qho kev sib piv ntawm 94: 6), lactose monohydrate, talc, magnesium stearate, hypromellose, plhaub muaj pes tsawg leeg: hypromellose, sodium lauryl sulfate, talc, talc.
Cov lus qhia tshwj xeeb
Thaum kho, nws yog ib qho tsim nyog yuav tsum nruj tsis pub noj ethanol.
Hauv cov neeg mob uas mob ntshav qab zib mellitus, tshwj xeeb tshaj yog thaum pib kho, nquag saib xyuas cov ntshav qabzib yog tsim nyog.
Cov tshuaj yog photosensitive, yog li ntawd, ampoules yuav tsum tau tshem tawm ntawm lub ntim tsuas yog tam sim ntawd ua ntej siv.
Kev sib txuam
Txo cov txiaj ntsig ntawm cisplatin.
Txhim kho cov teebmeem ntawm insulin thiab tshuaj qhov ncauj hypoglycemic.
Tsis sib haum nrog ringer thiab dextrose kev daws teeb meem, cov sib txuas (suav nrog lawv cov kev daws teeb meem) uas hnov mob nrog disulfide thiab SH pawg, ethanol.
Ethanol thiab nws cov metabolites nce qhov kev pheej hmoo ntawm kev phiv.
Cov Tshuaj Hauv Tshuaj
Cov tshuaj nquag ntawm cov tshuaj yog thioctic (alpha-lipoic) acid. Nws yog ib qho tshuaj antioxidant endogenous uas khi dawb. Thioctic acid yog tsim nyob rau hauv lub cev thaum lub zog oxidative decarboxylation ntawm alpha-keto acids. Nws yog coenzyme ntawm multienzyme ntau ceg hauv mitochondria thiab koom nrog oxidative decarboxylation ntawm alpha-keto acids thiab pyruvic acid.
Alpha-lipoic acid pab txo cov ntshav qabzib, nce qhov nce ntawm glycogen hauv daim siab thiab kov yeej cov tshuaj insulin. Los ntawm cov txheej txheem ntawm kev nqis tes ua, nws nyob ze rau cov vitamins ntawm pab pawg B.
Thioctic acid tswj kev ua kom muaj carbohydrate thiab lipid metabolism, txhim kho daim siab ua haujlwm thiab txhawb cov metabolism hauv cov roj cholesterol. Nws muaj cov tshuaj tiv thaiv hypolipidemic, hypoglycemic, hepatoprotective thiab hypocholesterolemic effect. Txhawb nqa cov khoom noj khoom haus zoo ntawm neurons.
Thaum siv meglumine ntsev ntawm alpha-lipoic acid (muaj qhov nruab nrab tshuaj tiv thaiv nruab nrab) hauv kev daws teeb meem rau kev tswj hwm qhov quav, qhov mob hnyav ntawm cov kev mob tshwm sim tuaj yeem txo qis.
Kev daws rau Txoj kev lis ntshav thiab mloog zoo rau kev npaj ntawm kev daws rau infusion
Txoj kev daws teeb meem, suav nrog uas npaj los ntawm cov mloog zoo, yog tswj hwm kom ncaj.
Cov koob tshuaj txhua hnub ntawm Thiogamma yog 600 mg (1 lub raj tshuaj tov lossis 1 ampoule ntawm mloog zoo).
Qhov tshuaj tau muab tshuaj yog siv rau 30 feeb (ntawm ntau npaum li 1,7 ml ib feeb).
Kev npaj ntawm kev daws los ntawm kev mloog zoo: cov ntsiab lus ntawm 1 ampoule yog tov nrog 50-250 ml ntawm 0.9% sodium chloride tov. Tam sim ntawd tom qab npaj, txoj kev daws teeb meem yuav tsum tau them nrog cov teeb meem hluav taws xob muaj teeb meem. Khaws tsis pub dhau 6 teev.
Thaum siv cov tshuaj npaj tau, nws yog ib qho tsim nyog yuav tsum tau tshem lub raj mis los ntawm cov thawv ntawv thiab tam sim ntawd npog nrog lub teeb tsom-thaiv. Txoj kev lis ntshav yuav tsum tau nqa tawm ncaj qha ntawm lub khob haus dej.
Lub sijhawm ntawm kev kho mob yog 2-4 lub lis piam. Yog tias tsim nyog, txuas ntxiv kho, tus neeg mob pauv mus rau hauv daim ntawv foos ntawm cov tshuaj.
Kev daws thiab feeb meej
- los ntawm cov kab mob endocrine: txo qis ntawm cov ntsiab lus ntawm cov piam thaj hauv cov ntshav (pom kev ntxhov siab, tawm hws ntau dhau, kiv taub hau, mob taub hau),
- nyob rau ntawm lub hauv nruab nrab hauv lub paj hlwb: ua txhaum lossis hloov hauv saj, pov tseg, qaug dab peg,
- los ntawm cov kab mob hemopoietic: mob ua paug hemorrhagic pob (purpura), mob thrombocytopenia, mob thrombophlebitis, pinpoint hemorrhages nyob rau hauv daim tawv nqaij thiab cov qog ua kua,
- nyob rau ntawm daim tawv nqaij thiab nqaij mos ua pob: eczema, khaus, tawm pob.
- nyob rau ib feem ntawm kev hloov khoom nruab nrog ntawm lub zeem muag: diplopia,
- kev ua xua: urticaria, kev ua haujlwm ntawm lub cev (tsis xis nyob, xeev siab, khaus) txog kev txhim kho anaphylactic kev poob siab,
- cov tshuaj hauv zos: hyperemia, voos, o,
- lwm tus: nyob rau hauv kev tswjhwm ntawm kev siv tshuaj sai - ua pa nyuaj, nce siab intracranial (qhov kev xav ntawm hnyav nyob hauv taub hau tshwm sim).
Coated ntsiav tshuaj
Cov ntsiav tshuaj yuav tsum tau noj ntawm qhov ncauj ntawm lub plab: nqos tag nrho thiab haus dej kom ntau.
Lub sijhawm kho, nyob ntawm qhov mob hnyav, yog 30-60 hnub.
Yog tias tsim nyog, 2-3 zaug hauv ib xyoos, koj tuaj yeem ua cov chav kawm ntxiv.
Sab sij huam
Kev daws thiab feeb meej
- los ntawm cov kab mob endocrine: txo qis ntawm cov ntsiab lus ntawm cov piam thaj hauv cov ntshav (pom kev ntxhov siab, tawm hws ntau dhau, kiv taub hau, mob taub hau),
- nyob rau ntawm lub hauv nruab nrab hauv lub paj hlwb: ua txhaum lossis hloov hauv saj, pov tseg, qaug dab peg,
- los ntawm cov kab mob hemopoietic: mob ua paug hemorrhagic pob (purpura), mob thrombocytopenia, mob thrombophlebitis, pinpoint hemorrhages nyob rau hauv daim tawv nqaij thiab cov qog ua kua,
- nyob rau ntawm daim tawv nqaij thiab nqaij mos ua pob: eczema, khaus, tawm pob.
- nyob rau ib feem ntawm kev hloov khoom nruab nrog ntawm lub zeem muag: diplopia,
- kev ua xua: urticaria, kev ua haujlwm ntawm lub cev (tsis xis nyob, xeev siab, khaus) txog kev txhim kho anaphylactic kev poob siab,
- cov tshuaj hauv zos: hyperemia, voos, o,
- lwm tus: nyob rau hauv kev tswjhwm ntawm kev siv tshuaj sai - ua pa nyuaj, nce siab intracranial (qhov kev xav ntawm hnyav nyob hauv taub hau tshwm sim).
Coated ntsiav tshuaj
Thiogamma yog feem ntau ua tau zoo. Tsis tshua muaj, suav nrog qee kis, cov kev mob tshwm sim tom qab no tshwm sim:
- kev ua xua: urticaria, tawv nqaij ua pob khaus, khaus khaus, muaj cov kab xaj ua haujlwm kom mus txog qhov tsim ntawm anaphylactic kev poob siab,
- los ntawm lub plab zom mov: mob plab, xeev siab, raws plab, ntuav,
- los ntawm cov kab mob endocrine: txo qis hauv cov ntsiab lus ntawm cov piam thaj hauv cov ntshav (pom kev ntxhov siab, nce tawm hws, kiv taub hau, mob taub hau).
Yeeb tshuaj sib cuam tshuam
- ethanol thiab nws cov metabolites: cov nyhuv ntawm thioctic acid tsis muaj zog txaus,
- cisplatin: nws cov kev ua kom tsawg dua
- glucocorticosteroids: lawv cov nyhuv tshuaj tiv thaiv yog ua kom zoo dua,
- tshuaj insulin, tshuaj hauv qhov ncauj hypoglycemic: lawv cov nyhuv ua tau zoo dua.
Thioctic acid khi cov hlau (hlau, hlau nplaum), yog li ntawd, yog tias tsim nyog, siv tib lub sij hawm npaj tau nrog lawv yuav tsum pom tsawg kawg 2 teev sib nrug ntawm koob tshuaj.
Thioctic acid reacts nrog cov suab thaj molecules, piv txwv li, muaj kev daws levulose (fructose), vim li ntawm cov insoluble complex tau tsim.
Hauv daim ntawv hais daws teeb meem, Thiogamma yog tsis sib xws nrog cov kev daws teeb meem uas hnov mob nrog disulfide thiab SH pawg, Ringer txoj kev daws teeb meem thiab dextrose daws teeb meem.
Cov tshuaj yeeb yaj kiab hauv qab no yog cov tshuaj tawm ntawm Thiogamma: Thioctacid BV, Lipoic acid, Tiolepta, Berlition 300, Thioctacid 600T.
Cov lus thiab cov xwm txheej ntawm kev cia
Khaws tawm ntawm qhov ncav cuag cov menyuam yaus, tiv thaiv los ntawm lub teeb, ntawm qhov kub txog li 25 ° C.
Txee lub neej yog 5 xyoos.
Nplooj ntawv no muab cov npe ntawm txhua Tiogamma cov yeeb yaj kiab sib xyaw ua ke thiab cov ntsiab lus rau kev siv. Cov npe ntawm cov pheej yig analogues, thiab koj kuj tuaj yeem sib piv cov nqi hauv cov khw muag tshuaj.
- Qhov pheej yig tshaj analogue ntawm Tiogamma:
- Cov analogue nrov tshaj plaws ntawm Tiogamma:
- Kev faib tawm ATX: Thioctic acid
- Cov khoom xyaw / cov khoom xyaw: thioctic kua qaub
Analogs los ntawm qhov taw qhia thiab cov qauv ntawm kev siv
Npe | Nqe hauv Lavxias | Nqe hauv Ukraine |
---|---|---|
-- | 230 UAH | |
niam | 20 RUB | 7 UAH |
Alder ntoo | 34 RUB | 6 UAH |
tib neeg cov txiv neej nqaij extract | 1736 tshiav | 71 UAH |
Chamomile officinalis | 33 rub | 7 UAH |
Roob tshauv | 43 txhuam | -- |
27 RUB | -- | |
-- | -- | |
Quav dev | 30 RUB | 7 UAH |
Immortelle xuab zeb, Hypericum perforatum, Chamomile | -- | 4 UAH |
bioglobin | -- | -- |
Roob tshauv, Rosehip | -- | -- |
Argentum nitricum, Acidum arsenicosum, Pulsatilla pratensis, Stryhnos nux-vomiсa, Carbo vegetabilis, Stibium sulfuratum nigrum | 203 tshiav | 7 UAH |
-- | 12 UAH | |
dalargin | -- | -- |
dalargin | -- | 133 UAH |
kev sib xyaw ntawm ntau cov tshuaj nquag | -- | 17 UAH |
Marshmallow, Blackberry, Peppermint, Plantain lanceolate, Chamomile, liab qab licorice, Cov thyme uas nquag, Muaj Fennel, Hops | -- | -- |
Hypericum perforatum, Calendula officinalis, Peppermint, Tshuaj chamomile, Yarrow | 35 txhuam | 6 UAH |
Lub cinquefoil yog erect | 150 rub | 9 UAH |
Xaws | -- | -- |
lecithin | -- | 248 UAH |
kev sib xyaw ntawm ntau cov tshuaj nquag | -- | 211 UAH |
hiav txwv buckthorn | -- | 13 UAH |
kev sib xyaw ntawm ntau cov tshuaj nquag | -- | -- |
Chokeberry | 68 rub | 16 UAH |
Valerian officinalis, Stinging nettle, Peppermint, Sowing oats, Loj plantain, Chamomile, Chicory, Rosehip | -- | -- |
Hawthorn, Calendula officinalis, Flax zoo tib yam, Peppermint, Plantain loj, Chamomile, Yarrow, Hops | -- | -- |
hom calamus, peppermint, tshuaj ntsuab chamomile, licorice liab qab, ntxhiab tsw dill | 36 tshiav | 7 UAH |
Celandine uas nquag muaj | 26 RUB | 5 UAH |
enkad | -- | -- |
-- | -- | |
-- | 20 UAH | |
nitisinone | -- | 42907 UAH |
miglustat | 155,000 RUB | 80 100 UAH |
sapropertin | 34 453 rub | 35741 UAH |
57 rub | 5 UAH | |
67 RUB | 7 UAH | |
cov zaub mov dubin | 2 RUB | 5 UAH |
Calendula officinalis, Medicinal chamomile, Licorice liab qab, Peb-ntu kab, Sage, Tshuaj eucalyptus | 48 rub | 7 UAH |
485 rub | 7 UAH | |
70 RUB | -- | |
ntshav pub dawb | -- | 7 UAH |
vitreous | 1700 RUB | 7 UAH |
homeopathic potencies ntawm ntau yam tshuaj yeeb dej caw | 31 RUB | 7 UAH |
-- | 20 UAH | |
homeopathic potencies ntawm ntau yam tshuaj yeeb dej caw | 3600 rub | 109 UAH |
uridine triacetate | -- | -- |
uridine triacetate | -- | -- |
Sib txawv muaj pes tsawg leeg, tuaj yeem ua ke nyob rau hauv kev taw qhia thiab cov qauv ntawm daim ntawv thov
Npe | Nqe hauv Lavxias | Nqe hauv Ukraine |
---|---|---|
Cov pa Cua, Elecampane siab, Leuzea safflower, Dandelion, Licorice liab qab, Rosehip, Echinacea purpurea | -- | 15 UAH |
Actinidia, Artichoke, Ascorbic Acid, Bromelain, Ginger, Inulin, Cranberry | -- | 103 UAH |
valine, isoleucine, leucine, lysine hydrochloride, methionine, threonine, tryptophan, phenylalanine, calcium pantothenate | -- | -- |
-- | 7 UAH | |
levocarnitine | 54 rub | 335 UAH |
levocarnitine | 1010 rub | 635 UAH |
levocarnitine | -- | 156 UAH |
levocarnitine | -- | 7 UAH |
levocarnitine | -- | 7 UAH |
-- | 7 UAH | |
levocarnitine | -- | 7 UAH |
-- | -- | |
-- | -- | |
levocarnitine | 16 RUB | 570 UAH |
ademethionine | -- | -- |
ademethionine | 400 RUB | 292 UAH |
ademethionine | 63 RUB | 7 UAH |
ademethionine | -- | 720 UAH |
ademethionine | -- | 7 UAH |
ademethionine | -- | 7 UAH |
citrulline malate | 10 RUB | 7 UAH |
imiglucerase | 67 000 rub | 56242 UAH |
agalsidase alpha | 148,000 RUB | 86335 UAH |
agalsidase beta | 158 000 rub | 28053 UAH |
laronidase | 29 000 RUB | 289798 UAH |
alglucosidase alpha | -- | -- |
alglucosidase alpha | 49 600 rub | -- |
halsulfase | 75 200 rub | 64 646 UAH |
idursulfase | 131 000 rub | 115235 UAH |
velaglucerase alpha | 142 000 rub | 81 770 UAH |
thaliglucerase alfa | -- | -- |
Txhawm rau kom ua ib daim ntawv teev cov khoom pheej yig ntawm cov tshuaj pheej yig, peb siv cov nqi uas yuav muab peb ntau tshaj 10,000 khw muag tshuaj thoob plaws hauv tebchaws Russia. Cov ntaub ntawv teev npe ntawm cov tshuaj thiab lawv cov analogues tau hloov kho tshiab txhua hnub, yog li cov ntaub ntawv muab rau ntawm peb lub vev xaib yog ib txwm hloov kho raws li niaj hnub no. Yog tias koj tsis tau pom ib qho analogue ntawm kev txaus siab rau koj, thov siv qhov kev tshawb nrhiav saum toj no thiab xaiv cov tshuaj ntawm kev txaus siab rau koj los ntawm cov npe. Ntawm nplooj ntawv ntawm txhua ntawm lawv koj yuav pom tag nrho cov kev xaiv ua tau rau cov qauv ntawm cov tshuaj xav tau, nrog rau tus nqi thiab chaw nyob ntawm cov khw muag tshuaj uas nws muaj.
Tiogamma kev qhia
LUS QHIA
ntawm kev siv cov tshuaj
Tiogamma
Pharmacological kev txiav txim
Cov tshuaj phiv tshuaj Thiogamma (Thiogamma-Turbo) yog thioctic (alpha-lipoic) acid. Thioctic acid tsim nyob rau hauv lub cev thiab pabcuam ua lub coenzyme rau lub zog metabolism ntawm alpha-keto acids los ntawm oxidative decarboxylation. Thioctic acid ua rau cov ntshav qabzib tsawg zuj zus, ua rau cov ncauj lus glycogen ntau zog hauv hepatocytes. Kev ua kom tsis haum plab los yog tsis muaj thioctic acid yog pom nrog ntau cov khoom sib ntxiv nyob rau hauv lub cev (piv txwv li, lub cev ketone), zoo li thaum intoxication. Qhov no ua rau muaj kev ntxhov siab hauv cov xov aerobic glycolysis. Thioctic acid muaj nyob rau hauv lub cev hauv daim ntawv ntawm 2 daim ntawv: txo thiab oxidized. Ob daim ntawv no yog physiologically dhia, muab cov tshuaj antioxidant thiab anti-toxic los.
Thioctic acid tswj kev ua kom cov metabolism ntawm carbohydrates thiab cov rog, zoo cuam tshuam cov metabolism hauv cov roj cholesterol, muaj cov kab mob hepatoprotective, txhim kho daim siab ua haujlwm. Muaj txiaj ntsig zoo rau kev rov ua dua tus txheej txheem hauv cov nqaij thiab cov plab hnyuv siab raum. Lub zog thaj tsam ntawm thioctic acid zoo ib yam li cov teebmeem ntawm cov vitamins B. Thaum lub sijhawm pib hla lub siab, thioctic acid muaj kev hloov pauv tseem ceeb. Hauv cov tshuaj muaj yees, pom tias cov tib neeg cov kev hloov pauv txawv.
Thaum siv sab hauv, nws yog sai thiab yuav luag nqus los ntawm cov hnyuv. Kev txiav txim siab tau tau nrog cov oxidation ntawm ib sab ntawm cov thioctic acid thiab nws txoj kev txuas. Kev tshem tawm ib nrab-lub neej ntawm Tiogamma (Tiogamma-Turbo) yog los ntawm 10 txog 20 feeb. Tsau tawm hauv cov zis, nrog metabolites ntawm thioctic acid predominating.
Kev ntsuas rau siv
Nrog rau cov ntshav qab zib ua kom yoog txhawm rau txhim kho cov nqaij mos rhiab mob.
Txoj kev ntawm daim ntawv thov
Thiogamma-Turbo, Thiogamma rau kev tswj hwm kev ua niam txiv
Thiogamma-Turbo (Thiogamma) yog npaj rau kev tswj hwm los ntawm tsoomfwv los ntawm cov leeg ntshav hla dej. Rau cov laus, ib koob tshuaj 600 mg (txheem ntawm 1 vial lossis 1 ampoule) yog siv ib hnub ib zaug. Txoj kev lis ntshav yog nqa tawm maj mam, rau 20-30 feeb. Lub chav kawm ntawm kev kho mob yog kwv yees li 2 txog 4 lub lis piam. Yav tom ntej, kev siv sab hauv ntawm Tiogamma hauv cov ntsiav tshuaj yog qhov pom zoo. Kev tswj hwm hauv tsoomfwv ntawm Thiogamma-Turbo lossis Thiogamma rau kev lis ntshav yog kho rau kev mob rhiab heev uas cuam tshuam nrog kev mob ntshav qab zib polyneuropathy.
Cov cai ntawm kev tswj hwm kev coj ntawm Thiogamma-Turbo (Thiogamma)
Cov ntsiab lus ntawm 1 lub raj mis ntawm Thiogamma-Turbo lossis 1 ampoule ntawm Thiogamma (600 mg ntawm cov tshuaj) yog yaj nyob rau hauv 50-250 ml ntawm 0.9% sodium chloride tov. Tus nqi ntawm kev tso ntshav ntshav - tsis ntau tshaj 50 mg ntawm thioctic acid hauv 1 feeb - qhov no kwv yees sib piv rau 1.7 ml ntawm ib qho kev daws ntawm Thiogamma-Turbo (Tiogamma). Kev noj tshuaj diluted yuav tsum siv tam sim ntawd tom qab sib xyaw nrog cov kuab tshuaj. Thaum lub sijhawm infusion, txoj kev daws teeb meem yuav tsum muaj kev tiv thaiv los ntawm lub teeb los ntawm cov khoom siv tshwj xeeb lub teeb tiv thaiv.
Tiogamma
Cov ntsiav tshuaj yog npaj rau kev siv sab hauv. Nws raug nquahu kom sau ntawv mus rau 600 mg ntawm cov tshuaj 1 zaug nyob rau ib hnub. Cov ntsiav tshuaj yuav tsum nqos tag nrho, noj tsis hais txog zaub mov, ntxuav cia nrog cov dej txaus. Lub sijhawm tiv thaiv kev kho ntsiav tshuaj yog los ntawm 1 mus rau 4 hlis.
Sab sij huam
Nruab nrab hauv lub paj hlwb: hauv cov tsis tshua muaj tshwm sim, tam sim ntawd tom qab siv cov tshuaj nyob rau hauv daim ntawv ntawm Txoj kev lis ntshav, txiav cov leeg txhaws muaj peev xwm ua tau.
Cov plab hnyuv siab raum: ua txhaum ntawm qhov xav ntawm saj, diplopia.
Hematopoietic system: purpura (mob tawm pob), mob thrombophlebitis.
Cov tshuaj tiv thaiv tsis haum ntshav: lub cev tsis haum tshuaj tuaj yeem ua rau anaphylactic ceeb, eczema lossis urticaria ntawm qhov chaw txhaj tshuaj.
Digestive system (rau Tiogamma ntsiav tshuaj): dyspeptic manifestations.
Lwm tus neeg: yog tias Tiogamma-Turbo (lossis Tiogamma rau kev tswj hwm kev coj noj coj ua) raug tswj hwm sai, kev ua pa nyuaj thiab qhov zoo ntawm qhov tawm tsam hauv lub taub hau yog qhov ua tau - cov kev cuam tshuam no tom qab txo qis rau qhov kev lis ntshav. Kuj tseem ua tau: hypoglycemia, kub tso xim, kiv taub hau, tawm hws, mob hauv lub plawv, txo ntshav qabzib, xeev siab, pom kev plooj, mob taub hau, ntuav, tachycardia.
Cov Yuav Tsum Muaj
Tus neeg mob cov mob uas yooj yim ua rau kev txhim kho ntawm cov kab mob lactic acidosis (rau Thiogamma-Turbo lossis Thiogamma rau kev tswj hwm kev tswj hwm),
cov me nyuam muaj hnub nyoog
cev xeeb tub thiab lactation
kev fab tshuaj tiv thaiv thioctic acid lossis lwm yam ntawm Thiogamma (Thiogamma-Turbo),
Hepatic lossis raum khiav tsis zoo,
mob theem ntawm myocardial infarction,
decompensated chav kawm ntawm kev ua pa lossis hlab plawv tsis ua haujlwm,
lub cev qhuav dej
haus cawv ntev,
mob kev nrawm ntawm cerebrovascular.
Cev xeeb tub
Thaum cev xeeb tub lossis pub mis niam, kev siv ntawm Thiogamma thiab Thiogamma-Turbo tsis pom zoo, vim tias tsis muaj kev paub txaus los ntawm kev siv tshuaj kho mob.
Yeeb tshuaj sib cuam tshuam
Qhov ua tau zoo ntawm cov tshuaj hypoglycemic thiab insulin yog nce ntxiv nrog Thiogamma (Thiogamma-Turbo). Txoj kev daws teeb meem Thiogamma-Turbo lossis Thiogamma yog tsis sib haum nrog cov kuab tshuaj uas muaj cov suab thaj nyob rau hauv, vim thioctic acid ua rau insoluble complex sib txuas nrog cov piam thaj. Hauv kev sim tshuaj hauv vitro, thioctic acid hnov mob nrog ionic hlau ntau zuj zus. Piv txwv li, qhov sib xyaw ua ke nrog cisplantine, magnesium, thiab hlau tuaj yeem txo cov nyhuv ntawm tom qab thaum ua ke nrog thioctic acid. Cov kuab tshuaj uas muaj cov tshuaj uas khi rau disulfide tebchaw lossis SH pawg tsis yog siv los daws qhov teeb meem ntawm Thiogamma-Turbo (Thiogamma) (piv txwv li, lub suab li tshuaj).
Noj ntau dhau
Nrog rau kev noj tshuaj ntau dhau ntawm Tiogamma (Tiogamma-Turbo), mob taub hau, ntuav, thiab xeev siab yog tau. Kev kho yog mob.
Daim ntawv tso tawm
Tiogamma Turbo
Tshuaj rau cov niam txiv infusion hauv 50 ml vials (1.2% thioctic acid). Hauv pob ntawv - 1, 10 fwj.Cov teeb kis tshwj xeeb hauv chaw ua si suav nrog.
Tiogamma ntsiav tshuaj
600 mg coated ntsiav tshuaj rau kev siv sab hauv. Hauv pob ntawm 30, 60 ntsiav tshuaj.
Thiogamma daws rau Txoj kev lis ntshav
Ib qho kev daws teeb meem rau kev tswj hwm hauv tsoomfwv hauv ampoules ntawm 20 ml (3% thioctic acid). Hauv pob - 5 ampoules.
Cia rau cov neeg mob
Hauv qhov chaw tiv thaiv los ntawm lub teeb, ntawm qhov kub li 15 txog 30 degrees Celsius. Kev daws npaj rau kev nkag rau txoj kev lis ntshav tsis yog nyob rau hauv cia. Ampoules thiab vials yuav tsum tsuas yog nyob hauv lub ntim thawj.
Muaj pes tsawg leeg
Tiogamma Turbo
Cov tshuaj nquag (hauv 50 ml): thioctic acid 600 mg.
50 ml ntawm Tiogamma-Turbo infusion daws muaj meglumine ntsev ntawm alpha-lipoic acid nyob rau hauv ib qho nyiaj ntawm 1167,7 mg, uas sib haum rau 600 mg ntawm thioctic acid.
Tiogamma
Cov tshuaj uas muaj sia (hauv 1 ntsiav tshuaj): thioctic acid 600 mg.
Cov tshuaj ntxiv: colloidal silicon dioxide, microcrystalline cellulose, talc, lactose, methylhydroxypropyl cellulose.
Tiogamma
Cov tshuaj nquag (hauv 20 ml): thioctic acid 600 mg.
Cov tshuaj ntxiv: dej rau txhaj, macrogol 300.
20 ml ntawm Tiogamma infusion daws muaj meglumine ntsev ntawm alpha-lipoic acid nyob rau hauv tus nqi ntawm 1167,7 mg, uas sib haum rau 600 mg ntawm thioctic acid.
Pharmacological pawg
Cov tshuaj hormones, lawv cov tshuaj tiv thaiv analogues thiab cov tshuaj tiv thaiv kabmob ntshav
Pancreatic hormone-based tshuaj thiab hluavtaws hypoglycemic
Synthetic hypoglycemic agents
Yam khoom muaj sia : Thioctic kua qaub
Yeem
Ntawm lub raj mis nrog yaj Thogamma-Turbo yaj, tshwj xeeb kev tiv thaiv lub teeb raug muab tso rau, uas txuas nrog rau cov tshuaj. Thiogamma daws muaj kev tiv thaiv nrog cov khoom tiv thaiv lub teeb. Hauv kev kho mob ntawm cov neeg mob, cov ntshav qabzib yuav tsum tau ntsuas qhov tsis tu ncua, raws li kev noj cov tshuaj insulin thiab hypoglycemic yuav tsum kho kom tsis txhob mob ntshav qab zib. Txoj kev kho mob thioctic acid yog txo qis nrog kev siv dej cawv (ethanol). Tsis muaj lwm cov lus ceeb toom tseem ceeb.
Txhua yam lus tau hais tawm rau kev qhia tawm thiab tsis yog lub laj thawj ntawm kev kho tus kheej lossis hloov cov tshuaj.
Cov yeeb yaj kiab sib piv ntawm cov tshuaj thiogamma raug nthuav tawm, raws li cov ntsiab lus kho mob, hu ua "txhais tau zoo" - cov tshuaj sib hloov uas muaj ib lossis ntau ntawm tib cov tshuaj nquag los ntawm lawv cov cuam tshuam rau lub cev. Thaum xaiv cov lus txhais, xav txog tsis yog lawv cov nqi nkaus xwb, tab sis kuj yog lub teb chaws ntawm kev tsim khoom thiab lub koob npe ntawm cov neeg tsim khoom.
Pharmacological kev txiav txim
Lub hauv paus tseem ceeb ntawm kev ua tshuaj npaj Tiogamma, tsis hais txog ntawm daim ntawv tso tawm, yog thiocticlossis alpha lipoic kua qaub (ob lub npe ntawm tib lub tshuaj lom biologically active). Qhov no yog lub ntuj ib feem ntawm cov metabolism, uas yog, feem ntau cov kua qaub no tau tsim nyob rau hauv lub cev thiab kev coj ua coenzyme ntawm mitochondrial ntau ceg lub zog metabolism ntawm pyruvic acid thiab alpha-keto acids raws txoj kev ntawm oxidative decarboxylation. Thioctic acid kuj yog qhov ua rau muaj kev phom sij, vim nws muaj peev xwm khi dawb radicals thiab tiv thaiv cov hlwb los ntawm lawv cov kev cuam tshuam hauv txoj kev no.
Lub luag haujlwm ntawm cov tshuaj tiv thaiv kuj tseem ceeb carbohydrate metabolismCov. Nws pab txhawm rau txo qis cov ntshav qabzib hauv cov ntshav dej thiab kev sib txuam ntawm glycogen hauv lub siab ua haujlwm. Vim tias muaj cov cuab yeej no, thioctic acid txo cov hlwb, uas yog, kev xav txog physiological rau cov tshuaj no ntau dua.
Kev koom tes hauv kev cai ntawm lipid metabolism hauvCov. Cov nyhuv ntawm cov tshuaj nquag ntawm cov metabolism ua cov tshuaj tiv thaiv hypocholesterolemic tshwj xeeb tshaj yog pom tau - cov kua qaub ua rau cov ntshav khiav qis thiab qis ntawm lipids thiab qhov feem pua ntawm cov lipids muaj ntau hauv cov ntshav ntau ntxiv). Ntawd yog, thioctic acid muaj qee yam antiatherogenic cov cuab yeej thiab ntxuav lub micro- thiab macrocirculatory txaj ntawm cov rog tshaj.
Detoxification teebmeem Kev npaj tshuaj yog tseem pom tau thaum muaj kuab lom nrog ntsev hlau hnyav thiab lwm hom tsiaj. Qhov kev txiav txim no txhim kho vim yog qhov ua kom muaj txheej txheem hauv lub siab, vim tias nws txoj haujlwm ua kom zoo dua qub. Txawm li cas los xij, thioctic acid tsis pab txhawb rau qhov kev tawm dag zog ntawm nws txoj kev xav tau physiological, thiab txawm hais tias rov ua li cas muaj zog hepatoprotective cov yam ntxwv.
Nws yuav tsum raug sau tseg tias alpha-lipoic acid-based tshuaj yog nquag siv rau, vim cov pov npav pab txo kev tsim cov glycation metabolites kawg thiab nce cov ntsiab lus rau physiologically ib txwm muaj nuj nqis. Ib yam ntxiv trophic qab haus huv txhim kho thiab cov ntshav endoneural, uas ua rau muaj qhov dav dav muaj txiaj ntsig ntawm lub xeev ntawm cov leeg ntshav ntawm lub cev thiab tiv thaiv kev txhim kho cov ntshav qab zib ib qho (ib chav nosological uas tsim los ntawm kev puas tsuaj rau cov hlab ntsha nrog kev nce siab ntxiv ntawm cov piam thaj thiab nws cov metabolites).
Hauv nws cov khoom siv tshuaj (hepato- thiab neuroprotective, detoxification, antioxidant, hypoglycemic thiab ntau lwm tus) thioctic acid yog qhov zoo sib xws cov vitaminsPawg B.
Thioctic lossis alpha lipoic acid tau txais cov koob npe nrov hauv tshuaj pleev ib cevim yog cov kws tshuaj hauv qab no rau ntsej muag tawv nqaij, uas feem ntau nyuaj rau kev saib xyuas:
- yuav tawm mus kev tiv thaiv tsis haum,
- zawm cov tawv nqaij quav txo qhov wrinkle qhov tobua rau lawv pom tsis txawm nyob hauv cov chaw nyuaj xws li cov ces kaum ntawm lub qhov muag thiab daim di ncauj,
- heals ib co kab mob ntawm (pob txuv) thiab nti, txij li thaum, nkag mus rau hauv cov tshuaj intercellular, nws stimulates lub cev tsis ua haujlwm ntawm kev rov qab ua haujlwm,
- zawm pores ntawm lub ntsej muag thiab tswj hwm kev muaj peev xwm muaj peev xwm sebaceous qogyog li pab daws cov teeb meem oily lossis tawv nqaij tawv,
- ua raws li lub zog ua kom muaj zog ntawm cov hauv paus chiv keeb endogenous.
Thiogamma, cov lus qhia rau kev siv (Txoj kev thiab ntau npaum li cas)
Cov lus qhia rau kev siv Thiogamma nws txawv raws li lub npe kws tshuaj ntawm cov tshuaj uas siv.
600 mg ntsiav tshuaj thov qhov ncauj ib zaug ib hnub. Tsis txhob zom lawv, vim tias lub plhaub yuav raug puas ntsoog, nws raug nquahu kom haus nrog me me ntawm cov dej. Lub sijhawm ntawm cov chav kawm yog kws kho mob ntawm tus kheej los ntawm tus kws kho mob koom, vim nws nyob ntawm qhov ntau ntawm cov kabmob. Feem ntau cov ntsiav tshuaj tau noj los ntawm 30 mus rau 60 hnub. Rov ua dua ib chav ntawm kev kho kev txuag yog ua tau 2-3 zaug hauv ib xyoos.
Tiogamma Turbo siv rau kev tswj hwm tsis pub siv me me los ntawm kev tso ntshav nrog kua. Qhov kev siv tshuaj txhua hnub yog 600 mg 1 zaug nyob rau ib hnub - xam ntawm cov ncauj lus ntawm ib lub raj mis los yog ampoule. Cov qhia yog nqa tawm qeeb, dhau 20-30 feeb, txhawm rau kom zam kev phiv los ntawm kev cuam tshuam sai ntawm cov tshuaj. Lub chav kawm ntawm kev kho mob ntawm hom tshuaj no yog los ntawm 2 mus rau 4 lub lis piam (lub sijhawm luv ntawm kev txuag kev kho yog vim muaj ntau dua plasma ntau ntau tom qab kev tswj hwm ntawm cov tshuaj).
Mloog zoo rau kev npaj tshuaj ntawm txoj hlab ntshav infusions siv raws li hauv qab no: cov ntsiab lus ntawm 1 ampoule (hais txog cov khoom tseem ceeb - 600 mg ntawm thioctic acid) yog sib xyaw nrog 50-250 isotonic (0.9 feem pua) sodium chloride tov. Tam sim ntawd tom qab npaj cov tshuaj sib tov, lub raj mis muaj qhov txheej txheem tiv thaiv me me (tsis poob, muaj ib kis ntawm ib pob tshuaj nyob rau hauv pob ntawm cov tshuaj). Tam sim ntawd, txoj kev daws yog muab los ntawm kev tso dej nrog txoj kev lis ntshav nrog ib lub sijhawm ntawm 20-30 feeb. Qhov ntau cia lub sij hawm ntawm qhov npaj Tiogamma tsis pub dhau 6 teev.
Thiogamma tuaj yeem siv rau kev tu tawv nqaij ntsej muag. Ua li no, thov daim ntawv kws tshuaj rau cov xa me nyuam hauv vials (ampoules nrog mloog zoo rau kev npaj ntawm cov tshuaj pleev ib ce tsis haum raws li cov khoom siv tshuaj pleev ib ce, vim tias lawv tuaj yeem ua rau muaj kev tsis haum tshuaj vim tias qhov ntau ntawm cov khoom siv tiv thaiv). Cov ntsiab lus ntawm ib lub raj mis yog thov nyob rau hauv daim ntawv dawb huv rau tag nrho saum npoo ntawm daim tawv nqaij ib hnub ob zaug - thaum sawv ntxov thiab yav tsaus ntuj. Ua ntej xws li kev ntxias, nws raug nquahu kom ntxuav nrog dej sov, xab npum dej kom ntxuav qhov rooj nkag ntawm lub qhov hws kom tob rau ntawm thioctic acid.
Analogs ntawm Thiogamma
Cov kev sib tw rau ATX Qib 4 code:
Thiogamma analogs ua rau pawg loj dua ntawm cov kws tshuaj, vim hais tias cov kev kho mob zoo dhau tam sim no muaj kev xav tau ntau. Nws yog qhov yooj yim dua rau kev siv tshuaj rau kev tiv thaiv kev mob neuropathies ntau dua li kho lawv tom qab nrog kev siv txoj kev txhawm rau, tau mus ntev thiab ua kom lub zog ntawm kev siv tshuaj kho mob. Yog li nrog rau Tiogamma yog siv:
Tiogamma: cov lus qhia rau kev siv thiab tshuaj xyuas
Lub npe Latin: Thiogamma
ATX Code: A16AX01
Cov khoom xyaw nquag: Thioctic acid (Thioctic acid)
Chaw tsim tshuaj paus: Verwag Pharma GmbH & Co. KG (Worwag Pharma GmbH & Co. KG), Beblingen, Lub Tebchaws Yelemees
Hloov kho cov lus piav qhia thiab yees duab: 05/02/2018
Thiogamma yog cov tshuaj uas tswj cov lipid thiab carbohydrate metabolism.