Siv puas tau cov tshuaj Amoxicillin thiab clarithromycin ib txhij?

Amoxicillin thiab clarithromycin yog cov tshuaj tua kab mob uas tiv thaiv tau ntau yam ntawm kev kis mob. Cov tshuaj siv tau rau ob leeg zuj zus thiab tib lub sijhawm. Thaum muab tshuaj tua kab mob, kev qhia thiab contraindications yuav tsum tau coj mus rau hauv tus account.

Amoxicillin thiab clarithromycin yog cov tshuaj tua kab mob uas tiv thaiv tau ntau yam ntawm kev kis mob.

Amoxicillin Cov Cwj Pwm

Cov tshuaj tua kab mob ntawm cov tshuaj pencillin series muaj cov kab mob bactericidal, raws li kev ua tiav ntawm kev ua tiav peptidoglycan, cov protein sib txuas uas tau siv los tsim cov qog cell ntawm microorganism. Cov kab mob hauv qab no yog nkag rau cov tshuaj:

gram-positive aerobes (streptococci, qee hom kab mob staphylococcus),
Gram-negative aerobes (meningococci, diphtheria bacillus, Klebsiella, gonococci, Salmonella, qee yam kab mob Proteus, Helicobacter pylori).

Cov kab mob me hauv qab no tiv thaiv Amoxicillin:

indole-positive hom ntawm Proteus,
kev qhia ntawv
enterobacter
Pseudomonas aeruginosa,
Kab mob cab (chlamydia, rickettsia, mycoplasma) uas mob intracellular,
anaerobic microorganisms.

Cov tshuaj siv rau hauv kev kho mob ntawm cov kab mob hauv qab no:

mob plab
mob txhab tawm ntawm lub plab thiab duodenum,
inflammatory txheej txheem nyob rau hauv lub genitourinary system,
purulent kis ntawm daim tawv nqaij thiab cov nqaij mos,
cov mob sib kis thiab mob ntawm lub ntsws ua pa,
uncomplicated gonorrhea
mob rau daim npluag qhwv
cov kab mob puas tsuaj rau lub plawv lub hnab.

Amoxicillin yog siv rau hauv kev kho mob ntawm lub plab zom mov.

Kev siv cov tshuaj tuaj yeem ua rau qhov kev txhim kho ntawm cov kev mob tshwm sim hauv qab no:

kev tsis haum tshuaj (urticaria, erythematous tawm pob, angioedema, febrile syndrome, leeg nqaij thiab mob pob txha),
kev txhim kho ntawm kev tiv thaiv kab mob uas tiv taus cov tshuaj tua kab mob,
cov khoom siv (neurological pathologies) (mob taub hau, qaug dab peg, tsis meej pem),
kho plab zom mov (mob plab, xeev siab thiab ntuav, tsis qab los, tso quav).

Amoxicillin yog sib kis hauv kev kis mob mononucleosis, mob hnyav plab hnyuv, mob leukemia. Nrog ceev faj, nws yuav tsum tau siv los ntawm cev xeeb tub thiab lactating poj niam.

Clarithromycin kev txiav txim

Cov tshuaj tua kabmob ntawm ntau tus kabmob macrolides txwv tsis pub tsim cov protein nyob hauv cov kab mob hauv lub cev. Clarithromycin inhibits kev sib kis ntawm cov kab mob tseem ceeb yam tsis muaj kev rhuav tshem lawv. Cov kab mob hauv qab no tseem ceeb rau cov tshuaj nquag:

gram-positive aerobes (streptococci, staphylococci, diphtheria bacillus, tuberculous mycobacteria),
gram-negative aerobes (diphtheria bacillus, borrelia, enterobacter, pasteurella, meningococcus, helicobacter pylori, moraxella),
Kab mob cab (chlamydia, ureaplasma, toxoplasma, mycoplasma) tso rau hauv lub cev
anaerobes (clostridia, peptococcus, peptostreptococcus, fusobacteria).

Clarithromycin inhibits qhov tsim los ntawm cov protein ua hauv cellular qauv ntawm cov kab mob.

Ob leeg ua ke

Kev siv cov tshuaj sib xyaw ua ke pab txo qis cov haujlwm ntawm Helicobacter pylori, uas yog lub hauv paus tseem ceeb ua rau mob txhab tawm ntawm lub plab zom mov. Cov kev kho mob zoo li no txo qhov ntxim nyiam ntawm kev loj hlob ntawm kev tawm tsam ntawm cov kab mob pathogenic rau cov tshuaj tua kab mob. Kev nthuav dav ntawm lub zog ntawm kev ua kom ua rau muaj kev tshem tawm sai dua.

Cov Yuav Tsum Muaj

Kev siv ua ke ntawm clarithromycin thiab amoxicillin yog contraindicated hauv qab no:

ib tug neeg tsis kam txais rau macrolides thiab penicillins,
mob raum thiab mob siab,
1 lub hlis ntawm cev xeeb tub
mob leukemia.

Nrog kev ceev faj, cov tshuaj tau noj nrog hemorrhagic diathesis, bronchial hawb pob, hauv lub sijhawm thib 2 thiab 3 ntawm kev xeeb tub.

Nqe lus piav txog cov tshuaj

Tau ntau xyoo, lub plab zom mov tau raug kho nrog kev noj zaub mov noj xwb, txo qis kev zais ntawm hydrochloric acid, thiab nyob rau hauv qhov xwm txheej hnyav, kev tshem tawm lub plab. Vim yog qhov kev tshawb pom ntawm kev sib txuas ntawm tus kab mob peptic rwj thiab Helicobacter pylori mob, uas tus sau tau txais qhov khoom plig Nobel, kev mob rwj pib kho nrog tshuaj tua kab mob, txuag cov neeg mob los ntawm qhov xav tau kev phais mob loj.

Muaj pes tsawg leeg ntawm clarithromycin thiab azithromycin suav nrog tib yam khoom xyaw.

Mechanism ntawm kev ua

Clarithromycin cuam tshuam kev tsim cov protein hauv cov kab mob ntawm cov kab mob, uas ua rau lawv nres rau hauv lawv txoj kev loj hlob thiab rov ua dua tshiab.

Amoxicillin cuam tshuam kev tsim ntawm ib qho tseem ceeb ntawm cov xovtooj ntawm phab ntsa ntawm peptidoglycan, pab txhawb kev tuag ntawm microorganism. Qhov sib txawv hauv cov txheej txheem ntawm kev ua ntawm cov tshuaj tua kab mob tso cai rau koj los ua ke, ua tiav cov txiaj ntsig zoo.

Clarithromycin thiab Amoxicillin siv ua ke hauv kev kho mob ntawm Helicobacter pylori, uas ua rau kev txhim kho ntawm kev mob plab, mob plab hauv plab thiab duodenum. Lawv yog ib feem ntawm ib qho ntawm cov kev tuaj yeem kho tau, tab sis siv tshwj xeeb hauv kev sib xyaw nrog cov tshuaj los ntawm lwm pab pawg kws tshuaj.

Kev ntsuas rau siv tib txhij

Rau kev siv rau kev siv ua ke, cov tshuaj yuav tau xaiv kom zoo. Cov tshuaj tua kab mob rau kev kho mob ntawm tus kab mob gastritis lossis mob ntsws yuav tsum tsis txhob muaj ntau yam tshwm sim. Cov khoom lag luam no yuav tsum tswj hwm lawv cov khoom hauv thaj chaw acidic thiab alkaline.

Cov tshuaj yuav tsum nkag mus rau cov ntshav hauv qhov xav tau, tsis txhob ua rau cov kua txob ua pa.

Cov tshuaj no muaj qhov sib cuam tshuam sib luag. Amoxicillin thiab Clarithromycin rhuav tshem cov phab ntsa cell ntawm cov kab mob, ua rau lub cev tsis tuaj yeem cuam tshuam ntawm cov kab mob yug me nyuam thiab cov neeg tuag.

Yuav noj cov tshuaj amoxicillin thiab clarithromycin ua ke li cas?

Nrog rau kev tswj hwm ua ke ntawm cov tshuaj no, lawv txhua tus yog kws kho raws cov lus qhia. Nrog txoj kev sib koom tes, qhov siab tshaj plaws ntawm ob qho tshuaj yog kws kho. Kev siv tshuaj rau txhua hnub yuav tsum tsis pub ntau dua 3 g, feem ntau cov neeg mob feem ntau tau sau npe 750-1500 mg rau ib hnub.

Qhov koob tshuaj txhua hnub tau muab faib ua ob peb koob tshuaj. Lub chav kawm ntawm kev kho mob tsawg kawg 10 hnub.

Tom qab cov tsos mob ntawm tus mob tau dhau mus, kev kho mob txuas ntxiv rau 2-3 hnub ntxiv. Ob qho tshuaj yeeb yog npaj rau kev tswj hwm qhov ncauj. Cov txheej txheem ntawm kev kho yog xaiv los ntawm tus kws kho mob.

Cov kws kho mob cov lus xav ntawm kev sib raug zoo ntawm Amoxicillin thiab Clarithromycin

Stepanov Victor Sergeevich, tus kws tshaj lij TB

Kev sib xyaw ntawm cov tshuaj no tau sau tseg hauv kev kho mob ntsws qhuav. Cov tshuaj muaj peev xwm ntawm nruab nrab, tab sis kev tawm tsam tubercle bacillus tsawg dua li lwm yam tshuaj.

Tkachenko Maria Nikolaevna, kws kho mob

Rau kev kho mob ntawm tus kab mob sinusitis thiab sinusitis, cov tshuaj no feem ntau tau sau tseg. Lawv ua tau zoo heev hauv kev tua cov kab mob zoo li no. Thaum kho, kev noj tshuaj ntau npaum li cas los ntawm kws kho mob yuav tsum pom.

Clarithromycin Cov Qauv Cim

Semi-hluavtaws cov tshuaj tua kabmob yog nyob ntawm pawg ntawm macrolides. Hauv kev pom zoo koob tshuaj, nws nres qhov luam tawm ntawm cov kab mob pathogenic, hauv qhov siab - nws rhuav tshem cov kab mob ntawm kev kis kab mob. Piv nrog rau lwm cov tshuaj tua kab mob ntawm cov naj npawb ntawm macrolides, Clarithromycin muaj qhov ua tau zoo dua tiv thaiv Helicobacter pylori. Cov tshuaj accumulates nyob rau hauv mucous daim nyias nyias ntawm lub plab, uas tso cai rau nws yuav tsum tau siv rau inflammatory mob ntawm no hloov khoom nruab nrog.

Kuv puas tuaj yeem siv clarithromycin thiab amoxicillin tib lub sijhawm?

Kev siv ua ke ntawm cov tshuaj tua kab mob pab tshem tawm cov kab mob xws li:

salmonella
mob streptococcus
staphylococcus
E. coli
mob chlamydia.

Clarithromycin thiab Amoxicillin yog siv rau cov kabmob no:

cov kab mob ntawm cov kab mob hauv lub plab (gastritis, pais plab rwj, hlav qog ua rau los ntawm kev ua si ntawm Helicobacter pylori),
kev ua pa rau mob ntsws (mob ntsws, mob ntsws, mob hom mob ntsws uas tiv taus kev kho mob),
mob kab mob ntawm cov genitourinary system (mob ntsws, mob chlamydial urethritis, mob ncauj lus, mob rau lub tsev me nyuam thiab mob hnyuv taum, cystitis, pyelonephritis).

Clarithromycin yog siv rau cov kab mob ntawm lub plab zom mov.

Hauv kev kho mob mob plab, clarithromycin thiab amoxicillin yog ntxiv nrog omeprazole. Qhov tshwm sim ntawm kev rov qab los hauv qhov no yog 95%. Muaj ntau cov tshuaj suav daws muaj 3 cov khoom xyaw nquag.

Cov nyhuv pharmacological ntawm cov tshuaj tua kab mob hauv khub

Helicobacter pylori ua rau muaj cov tshuaj tua kab mob sai sai. Kev siv 2 lub tshuaj pabcuam pab ua kom txo qhov zoo li ntawm qhov tsis kam. Amoxicillin txuam nrog clarithromycin sai txo kev kis tus kab mob. Yeeb tshuaj txhawb nqa ib leeg qhov kev coj ua. Qhov no ua tau vim muaj qhov sib txawv ntawm cov kab mob pathogenic.

Lub tswv yim ntawm cov kws kho mob

Victoria, hnub nyoog 48 xyoo, kws tshaj lij TB, Moscow: “Clarithromycin thiab Amoxicillin feem ntau tau txhaj tshuaj tiv thaiv kab mob ntsws yam tsis haum tshuaj. Cov tshuaj yog ntawm nruab nrab zoo, txawm li cas los xij, tuberculous mycobacteria maj mam tsim kho kom zoo rau lawv. Kev phiv loj heev nrog kev noj tshuaj yog muaj tsawg. Ntsiav tshuaj yuav ua rau mob taub hau, xeev siab thiab dias taub hau. Cov tsos mob tsis kaj siab ploj mus tom qab kev kho tiav. "

Maria, 39 xyoo, kws kho mob, Novosibirsk: “Kev sib xyaw ntawm cov tshuaj tua kab mob feem ntau yog siv los kho tus mob txha caj dab ntev thiab mob siab. Hauv kev kho mob gynecology, tshuaj siv los kho endometritis, adnexitis, chlamydia. Cov tshuaj muaj txiaj ntsig zoo tiv thaiv kev tawm tsam cov kab mob me. Thaum kho, kev noj ntau npaum uas kws kho mob sau yuav tsum tsis pub tshaj. Yog ua tsis tiav cov cai no ua rau muaj kev pheej hmoo phiv. "

Amoxicillin tsis raug siv rau kev txwv ib leeg rau qee yam hauv cov tshuaj.

Kev Ntsuam Xyuas Rau Neeg Mob

Natalia, 33 xyoo, Izhevsk: “Tom qab mob khaub thuas, mob ntsws txhaws tag. Tus kabmob muaj kabmob tsawg kawg 4 zaug hauv ib xyoos. Qhov hnoos hnyav tau cuam tshuam nrog kev pw thiab ua haujlwm. Kuv tig mus rau tus kws kho mob ntsws ntsws uas kho cov kev kho mob, uas suav nrog noj Clarithromycin thiab Amoxicillin. Tom qab kho, mob ntsws los ua phem dua qhov muaj ntau. Thaum noj tshuaj, xeev siab qee zaum tshwm sim, uas ploj tom qab kev kho mob tas. "

Sergey, 58 xyoo, Voronezh: “Lub sijhawm kuaj xyuas, pom muaj mob rwj plab. Kev tsom xam pom tias tus kab mob yog los ntawm Helicobacter pylori kab mob. Clarithromycin tau raug sau tseg nrog amoxicillin. Nws coj cov tshuaj ntawm 10 hnub, tom qab ntawd nws dhau qhov kev ntsuam xyuas ntxiv. Tus saib xyuas sawv cev tsis yog tus nrhiav. "

Phiv los ntawm amlodipine thiab clarithromycin

Nrog rau kev siv cov tshuaj tiv thaiv kab mob tib si, cov kev mob tshwm sim hauv qab no tuaj yeem pom:

xeev siab thiab ntuav
kiv taub hau
khaus tawv nqaij
plab hnyuv dysbiosis,
kev kho mob npaws fwm dav dav,
vitamin tsis txaus.

Tso daim ntawv thiab nqi

Cov nqi rau clarithromycin yuav txawv raws qhov chaw tsim tshuaj paus:

Ntsiav tshuaj
- 250 mg, 14 pcs. - 195 p,
- 500 mg, 14 pcs. - 200 - 590 r,
Ntev ua ntsiav tshuaj 500 mg, 7 pcs. - 380 - 400 r,
Cov tshuaj ntsiav 250 mg, 14 pcs. - 590 p.

Cov tshuaj hu ua "Amoxicillin" kuj tseem ua los ntawm cov tuam txhab sib txawv (kom yooj yim, cov nqi ntawm cov ntsiav tshuaj thiab cov tshuaj ntsiav tau muab raws li 20 pcs.):

Kev ncua rau kev tswj hwm qhov ncauj ntawm 250 mg / 5 ml, ib fwj dej 100 ml - 90 r,
Kev rau txim rau kev txhaj tshuaj 15%, 100 ml, 1 pc. - 420 r
Cov tshuaj ntsiav / ntsiav tshuaj (rov ua dua kom txog 20 pcs.):
- 250 mg - 75 r,
- 500 mg - 65 - 200 r,
- 1000 mg - 275 p.

Kuv puas tuaj yeem siv Clarithromycin thiab Amoxicillin tib lub sijhawm?

Kev txiav txim siab txiav txim siab nyob rau hauv qee kis tshwj xeeb nws muaj peev xwm coj Clarithromycin thiab Amoxicillin ua ke yuav tsum txiav txim siab rau txhua tus neeg mob. Rau qhov no, xwm thiab mob hnyav ntawm tus kabmob, tiv taus tshuaj, yav dhau los ua cov haujlwm ntawm kev siv tshuaj los tiv thaiv tus kabmob yog coj mus rau hauv tus lej. Piv txwv li, nrog mob caj dab lossis mob plab ua rau thawj zaug, coj mus rau hauv kev tshawb pom ntawm Helicobacter, xws li kev sib txuam ntawm cov tshuaj yog qhov tsim nyog.

Yog tias qhov mob kiav txhab loj, lossis yav dhau los siv cov tshuaj no tsis muaj txiaj ntsig zoo, lawv tuaj yeem hloov los ntawm kev sib xyaw ntawm De-nol + Tetracycline + Metronidazole. Cov tshuaj no muaj qhov ua tau zoo, tab sis lawv cov kev phiv ntau dua thiab muaj zog.

Hauv rooj plaub thaum tus neeg mob tsis ua siab ntev rau Clarithromycin lossis Amoxicillin, cov tshuaj yuav hloov nrog Metronidazole. Xws li kev sib txuas yog qhov sib npaug thiab nws tsis tuaj yeem hais qhov twg yog qhov zoo dua.

Yuav ua li cas clarithromycin ua hauj lwm?

Qhov no yog cov tshuaj tua kab mob ib nrab hnub uas yog ib feem ntawm pawg macrolide. Nws muaj cov antimicrobial, tiv thaiv mob thiab bacteriostatic cov yam ntxwv. Cov tshuaj cuam tshuam kev cuam tshuam ntawm cov protein ua ke hauv lub cell ntawm ib qho kev sib txawv ntawm neeg txawv teb chaws, tiv thaiv lawv txoj kev loj hlob thiab rov ua dua tshiab.

Cov tshuaj nquag (clarithromycin) muaj peev xwm los tsim lub siab ntawm lub plab siab dua li ntawm cov ntshav cov ntshav, yog li nws siv feem ntau hauv kev mob plab.

Mob ncauj plab

Nrog lub plab zom mov, cov chav kawm ntawm kev pub nkag yog xaiv los ntawm tus kws kho mob tshwj xeeb.

Cov qauv txheej txheem suav nrog 3 tshuaj thiab zoo li no:

Omeprazole (prostaglandin) - 1 ntsiav tshuaj (20) mg.
Amoxicillin - 1 tshuaj ntsiav (1000 mg).
Clarithromycin - 1 ntsiav tshuaj (500) mg.

Siv 2 zaug ib hnub rau 7-14 hnub. Prostaglandin yuav tsum haus cawv 20 feeb ua ntej noj mov, thiab tshuaj tua kab mob nrog zaub mov noj.

Phiv los ntawm amoxicillin thiab clarithromycin

Feem ntau, ib qho txog ntawm ob tus neeg ua haujlwm tua kab mob tuaj yeem ua rau muaj kev phiv:

xeev siab
ntuav
dysbiosis,
ua xua nyob rau hauv daim ntawv ntawm daim tawv nqaij ua pob ua xua,
kiv taub hau
hypovitaminosis,
lub cev tsis muaj zog.

Amoxicillin ua ke nrog clarithromycin tuaj yeem ua rau xeev siab thiab ntuav.

Qhov kev tshwm sim ntawm cov kev mob tshwm sim tsis yog qhov qhia tau rau kev tshem tawm yeeb tshuaj, koj yuav tsum sab laj tus kws kho mob kom muab tswv yim.

Yuav ua li cas noj tib lub sijhawm?

Hauv kev kho mob rau mob txhab, Amoxicillin noj 2 zaug ib hnub rau 1000 mg, thiab Clarithromycin 2 zaug ib hnub rau 500 mg. Lub chav kawm ntawm kev kho mob yuav tsum tau 7 hnub. Txoj kev kho tsis tshua muaj teeb meem tshwm sim thiab tau txais ntau cov kev txheeb xyuas los ntawm ob qho tib si tus neeg mob thiab kws kho mob. Nws tuaj yeem nqa tau ob qho tib si hauv tsev kho mob thiab ntawm tus neeg mob sab nraud.

Yog tias qhov kiav txhab ntau zuj zus, thiab qhov kev kho mob tsis pab, qhov ua kom “poob siab kho” yog qhov ua tau. Nws muaj nyob hauv lub sijhawm teem ntawm Amoxicillin ntawm kev noj tshuaj ntau npaum li 3000 g ib hnub rau 2 rau 3 koob rau 10 txog 14 hnub. Qhov kev kho mob no tuaj yeem ua rau ntau cov kev mob tshwm sim thiab yuav tsum tau nqa tawm tshwj xeeb hauv tsev kho mob.

Kab lus no tsuas yog rau kev ua ntaub ntawv xwb.

Tsis txhob muab tshuaj rau tus kheej. Ua ntej siv cov tshuaj, nco ntsoov sab laj nrog kws kho mob

Omeprazole, Amoxicillin, Clarithromycin

Thaum sib piv nrog cov tshuaj tua kab mob, Omez (Omeprazole) ib txwm siv, uas txo cov acidity hauv plab, cuam tshuam rau kev ua haujlwm tsis zoo ntawm Helicobacter. Tsis tas li, hauv cov kua qaub qis, mob rwj yuav kho sai thiab cov tshuaj tua kab mob tuaj yeem ua haujlwm ib txwm, thiab tsis tawg.

Lub tshuab ua haujlwm ntawm cov tshuaj yog ua raws li kev txwv ntawm lub twj tso kua mis ntawm tes, uas tas li tso H + rau hauv lumen ntawm lub plab. Thaum tsis muaj hydrogen ions, chlorine ions Cl - tsis tuaj yeem tiv tauj ib yam dab tsi thiab, raws li, kev tsim cov hydrochloric acid (HCl) yuav tsis tshwm sim. Raws li qhov tshwm sim, acidic ib puag ncig ntawm lub plab ua ntau nruab nrab.Helicobacter pylori tuag nyob hauv nruab nrab thiab alkaline ib puag ncig, uas tseem ua rau kom rov zoo dua.

Yuav siv sijhawm ua ke li cas?

Omez regimen txuam nrog clarithromycin thiab amoxicillin yog qhov yooj yim heev. Omez noj thaum lub sijhawm mus pw hauv ib qhov tshuaj ntawm 20 mg rau 7 hnub. Tag nrho peb cov tshuaj qaug cawv ib txhij thiab ib chav kawm.

Yog tias hloov los ntawm Clarithromycin thiab Amoxicillin, De-nol + Tetracycline + Metronidazole regimen siv, ces Omez yog qaug cawv ib hnub ob zaug, 20 mg ib.