Cov kev tshuaj ntsuam xyuas ntshav sab saum toj

Nws thiaj li tau tshwm sim hais tias thaum kuaj lub cev tom ntej hauv kev kuaj ntshav biochemical, Kuv pom cov roj (cholesterol) nce, tsis ntau, tsis ntau 7.3.

Kev siv cov roj (cholesterol) yog qhov muaj kev pheej hmoo ntawm lub plawv thiab hlab ntsha tawg, vim tias cov roj (cholesterol) nyob ua ke rau cov hlab ntshav thiab nqaim lawv cov lumen, ntxiv rau, cov ntshav uas muaj cov roj cholesterol siab yuav ua ntshav khov. Ob qho xwm txheej no tuaj yeem ua rau txhaws ntawm lub nkoj lossis txoj kev sib tsoo. Tu siab ...

Tus kws kho mob, raws li cov txiaj ntsig ntawm kev ntsuam xyuas, tau hais kom kuv kho - noj tshuaj rau qhov txo cov roj (cholesterol) Atoris, hauv kev noj tshuaj ntawm 10 mg, ib hnub ib zaug thiab rov ua ntsuas cov roj (cholesterol) ob lim piam tom qab pib tshuaj.

• Atoris (Atorvastatin) yog yeeb tshuaj los ntawm pab pawg ntawm statins.
• Chaw tsim tshuaj paus - Krka, Slovenia
• Cov naj npawb ntawm cov ntsiav tshuaj rau ib pob - 30 pcs.
• Nqe - 358 rubles

Cov ntsiav tshuaj yog me me, dawb

Atoris yog tshuaj rau cov ntshav siab cov ntshav siab thiaj li yuav txo cov roj hauv lub cev tsis xwm yeem, thiab tom qab ntawv tswj nws qhov kev txwv.

Cov Khoom Qhia

• thawj hyperlipidemia IIa thiab IIb hom raws li kev faib tawm ntawm Frederickson, suav nrog polygenic hypercholesterolemia, xyaw hyperlipidemia, heterozygous tsev neeg hypercholesterolemia, kom qis dua qib ntawm tag nrho roj, apolipoprotein B, LDL cov roj cholesterol, triglycerides hauv cov ntshav
• tsev neeg homozygous hypercholesterolemia, kom qis dua qib ntawm tag nrho roj, apolipoprotein B, LDL cov roj cholesterol,

Cov Yuav Tsum Muaj

• cov leeg pob txha pathology,
• kev tiv thaiv tsis haum rau atorvastatin, lwm cov khoom xyaw Atoris, los yog kev sib xyaw ntawm,
• daim siab ua hauj lwm,
• pathology ntawm daim siab ua mob rau ntu mob (nrog rau dej cawvlossis nquag muaj mobkab mob siab,
• lactase deficiency, lactose intolerance thiab qabzib-galactose malabsorption syndrome,
• Kab mob ntsws ntawm ntau yam keeb kwm
• txhawb nqa qib hepatic transaminases ntawm qhov tsis paub keeb kwm, uas yog ntau dua 3 zaug siab dua qhov kev cai,
• hnub nyoog txog 18 xyoo
• sij hawmpub niam misthiab ntawm cev xeeb tub.

Raws li kws kho mob tau hais tseg, Kuv coj Atoris 10 mg ib hnub ib zaug. Koj tuaj yeem nqa cov tshuaj txhua lub sijhawm ntawm hnub, tab sis koj yuav tsum tau ua tib lub sijhawm.

Ob lub lis piam tom qab kuv dhau kev tswj xyuas ntshav, nws pom tias theem ntawm cov roj cholesterol hauv kuv cov ntshav qis thiab ua qhov qub - 5.7.

Feem ntau cov roj (cholesterol) hauv cov ntshav

Txhawm rau kom ua tiav cov txiaj ntsig, Kuv tau raug xaiv los txuas ntxiv noj Atoris ntawm tib lub sijhawm rau lwm ob lub lis piam, thiab tom qab ntawd txo qhov koob tshuaj rau 5 mg ib hnub ib zaug.

Ntawm chav kawm, nws yooj yim, noj tshuaj thiab voila, kev ntsuam xyuas yog qhov qub. Tab sis peb nkag siab tias yog tias cov roj (cholesterol) yog nce, ces koj yuav tsum xub kho koj li kev noj zaub mov kom zoo. Goodbye sausages, brisket, waffles, Kuv tau zoo nrog koj!

Cov tshuaj Atoris ua txhua yam uas kuv xav tau los ntawm nws. Nws maj nrawm txo qib roj hauv cov ntshav thiab tsis ua rau kuv tsis xis nyob lossis phiv, ib pob txaus rau kuv rau ib hlis twg noj.

Siv cov ntsiav tshuaj, koj tuaj yeem txo qis cov roj cholesterol sai, tab sis kev tswj nws kom ruaj ntseg yog qhov zoo dua nrog kev noj zaub mov kom raug, vim tias kev noj cov ntsiav tshuaj rau lub neej yog qee yam tsis zoo.

Ua tsaug rau txhua tus neeg uas nyeem kuv qhov kev ntsuam xyuas, muaj ib hnub zoo!

Statins: lawv ua li cas, kev ntsuas thiab contraindications, tshuaj xyuas tshuaj, dab tsi los hloov

Tau ntau xyoo tsis muaj kev vam meej nrog CHOLESTEROL?

Lub taub hau ntawm lub koom haum: “Koj yuav xav tsis thoob tias yooj yim npaum li cas nws los txo cov roj (cholesterol) los ntawm kev siv tshuaj txhua hnub.

Cov roj (cholesterol), lossis cov roj cholesterol yog ib yam khoom uas ua haujlwm tseem ceeb hauv tib neeg lub cev. Cov no suav nrog:

• Kev koom tes ua cov khoom siv hauv tsev hauv cov txheej txheem lub neej ntawm yuav luag txhua lub hlwb ntawm lub cev, vim tias cov roj (molecules) cov roj (cholesterol) nyob rau hauv cov cell ua rau lub cev ua rau nws muaj zog, ua tau yooj yim thiab “muaj txiaj ntsig”,
• Kev koom tes hauv cov txheej txheem kev zom thiab tsim kom muaj cov kua tsib cov acids uas tsim nyog rau kev tawg thiab nqus ntawm cov rog hauv cov hnyuv,
• Kev koom tes hauv kev tsim cov tshuaj hormones hauv lub cev - cov tshuaj hormones steroid ntawm cov qog adrenal thiab cov tshuaj hormones poj niam txiv neej.

Ib qho roj cholesterol ntau hauv cov ntshav ua rau qhov tseeb tias nws cov lwg me me tuaj yeem muab tso rau ntawm phab ntsa ntawm cov hlab ntsha (feem ntau yog cov hlab ntsha). Atherosclerotic plaques yog tsim los cuam tshuam cov ntshav ntws los ntawm cov leeg thiab qee zaum, ua ke nrog cov ntshav txhaws nrog lawv, ua tiav lumen ntawm cov hlab ntsha, pab txhawb kev txhim kho lub plawv thiab mob hlab ntsha tawg.

Cov cai ntawm cov roj (cholesterol) tag nrho hauv cov ntshav ntawm tus neeg laus yuav tsum tsis pub ntau dua 5.0 mmol / l, hauv cov neeg mob mob plawv tsis pub tshaj 4,5 mmol / l, thiab hauv cov neeg mob myocardial infarction tsis pub tshaj 4.0 mmol / l.

Dab tsi yog statins thiab lawv ua haujlwm li cas?

Hauv qhov xwm txheej uas tus neeg mob tau muaj kev pheej hmoo ntawm kev tsim cov myocardial infarction vim yog atherosclerosis thiab cov roj metabolism hauv lub cev tsis txaus siab, nws tau pom tias siv tshuaj lipid-txo cov tshuaj ntev ntev.

Statins yog hypolipidemic (lipid-txo qis) cov tshuaj, cov txheej txheem ntawm kev txiav txim ntawm uas yog txhawm rau enzyme uas txhawb nqa kev tsim cov roj (cholesterol). Lawv ua haujlwm rau lub hauv paus ntsiab lus ntawm "tsis muaj enzyme - tsis muaj roj". Tsis tas li ntawd, vim muaj cov txheej txheem ncaj qha, lawv pab txhawb kev txhim kho ntawm cov txheej hauv cov hlab ntshav ntawm theem thaum cov kab mob atherosclerosis tseem tsis tuaj yeem kuaj mob, tab sis kev ua haujlwm ntawm cov cholesterol nyob ntawm phab ntsa yog twb pib - thaum ntxov ntawm atherosclerosis. Lawv kuj muaj cov txiaj ntsig zoo ntawm rheological yam ntxwv ntawm cov ntshav, txo viscosity, uas yog qhov tseem ceeb uas tiv thaiv kev tsim cov ntshav txhaws thiab lawv txuas rau cov quav hniav.

Kev ua tau zoo tshaj plaws tam sim no tau lees paub tias yog qhov tseeb tshaj plaws ntawm statins, uas muaj atorvastatin, cerivastatin, rosuvastatin thiab pitavastatin yog cov tshuaj nquag. Cov tshuaj ntawm cov tub ntxhais tiam tam sim no tsis tsuas yog txo cov theem "phem" cov roj cholesterol, tab sis kuj nce cov ntsiab lus ntawm "zoo" hauv cov ntshav. Cov no yog cov statins zoo tshaj plaws rau hnub tim, thiab cov txiaj ntsig ntawm lawv txoj kev siv txhim kho twb tau nyob hauv thawj lub hlis ntawm tas mus li siv. Statins tau sau tseg ib hnub ib hnub thaum hmo ntuj, lawv tuaj yeem ua ke hauv ib ntsiav tshuaj nrog lwm cov tshuaj mob plawv.

Kev siv ywj pheej ntawm cov tshuaj statins yam tsis tau sab laj nrog kws kho mob yog qhov tsis tuaj yeem tsis tau, txij li ua ntej noj cov tshuaj, nws yog qhov yuav tsum txiav txim siab txog qib roj hauv cov ntshav. Ntxiv mus, yog tias cov qib roj cholesterol tsawg dua 6.5 mmol / l, tsis pub dhau rau lub hlis koj yuav tsum sim txo nws nrog zaub mov noj, muaj kev noj qab haus huv, thiab tsuas yog tias cov kev ntsuas no tsis muaj txiaj ntsig, tus kws kho mob txiav txim siab txog kev teem caij statins.

Los ntawm cov lus qhia rau kev siv statins, koj tuaj yeem hais lub ntsiab lus tseem ceeb:

Kev ntsuas rau statins

Lub ntsiab tseem ceeb yog hypercholesterolemia (cov roj (ntshav siab)) nrog qhov tsis muaj txiaj ntsig ntawm txoj kev tsis siv tshuaj yaj yeeb thiab tsev neeg (mob) hypercholesterolemia nrog qhov tsis muaj txiaj ntsig ntawm kev noj haus.

Kho cov tshuaj statins yog qhov yuav tsum tau ua rau cov neeg muaj hypercholesterolemia cuam tshuam nrog cov kab mob hauv qab no, txij li lawv siv nrog lwm cov tshuaj uas kws kho mob ua rau txo qis kev pheej hmoo sai sai:

• Cov neeg laus dua 40 nrog qhov muaj feem yuav muaj kab mob plawv heev,
• Kab mob rau lub plawv, angina pectoris,
• Myocardial infarction
• Aorto-coronary bypass phais los yog stent tso rau myocardial ischemia,
• Mob stroke
• Kev pham
• Mob ntshav qab zib mellitus
• Tus neeg mob cia li tuag tam sid hauv cov neeg txheeb ze hauv qis dua 50 xyoo.

Cov Yuav Tsum Muaj

Cov tshuaj tiv thaiv suav nrog kev ua haujlwm tsis zoo ntawm daim siab ua haujlwm (mob siab, mob ntsws) hauv cov theem nquag, kev ua xua nrog kev tswj hwm yav dhau los ntawm cov tshuaj. Statins yuav tsum tsis txhob noj los ntawm cev xeeb tub thiab lactating cov poj niam, nrog rau cov poj niam uas muaj hnub nyoog yug me nyuam uas tsis siv txoj hauv kev tswj kom muaj txiaj ntsig. Statins tsis cuam tshuam rau lwm hom metabolism (protein, carbohydrate, purine metabolism), yog li lawv tuaj yeem siv rau cov neeg mob ntshav qab zib, mob gout thiab lwm yam kab mob sib kis.

Sab sij huam

Tsawg dua li 1% ntawm cov neeg mob noj statins rau lub sijhawm ntev thiab txuas ntxiv tsim kev kub ntxhov, pw tsaug zog, ua rau cov leeg tsis muaj zog, hnov ​​qab, tsis hnov ​​qab, lub plawv dhia, lub ntsej muag poob thiab nce ntshav siab, txo qis platelet ntshav ntau, txhaws ntswg, kub siab , mob plab, xeev siab, tso quav tsis txaus, tso zis heev, tsawg zog, mob nqaij thiab pob qij txha, rhabdomyolysis (puas tsuaj rau cov leeg nqaij), tawm hws, ua xua.

Ntau tshaj li 1% ntawm cov neeg mob tau kiv taub hau, xeev siab, mob hauv lub plawv, hnoos qhuav, txhaws ntswg, ua rau tawv nqaij, ua rau tawv nqaij ntau dhau rau hnub ci, ua rau tawv nqaij - khaus, liab, liab.

Statins tuaj yeem ua ke nrog lwm cov tshuaj?

Raws li cov lus pom zoo ntawm WHO thiab American Heart Association, statins yog cov tshuaj tseem ceeb hauv kev kho cov mob plawv nrog cov kev pheej hmoo ntawm cov teeb meem thiab myocardial infarction. Kev muab tshuaj ib leeg los txo cov roj (cholesterol) tsis txaus, yog li cov tshuaj tseem ceeb muaj nyob hauv cov qauv kev kho mob - cov no yog beta - blockers (bisoprolol, atenolol, metoprolol, thiab lwm yam), cov tshuaj tiv thaiv kab mob antiplatelet (tshuaj aspirin, tshuaj aspirin Cardio, tshuaj aspicor, thrombo Ass, thiab lwm yam), ACE inhibitors ( enalapril, perindopril, quadripril, thiab lwm yam) thiab statins. Ntau cov kev tshawb fawb tau ua uas tau pom tseeb tias kev siv cov tshuaj no ua ke yog kev nyab xeeb. Ntxiv mus, nrog kev sib xyaw ntawm, piv txwv li, pravastatin thiab cov tshuaj aspirin hauv ib ntsiav tshuaj, qhov kev pheej hmoo ntawm kev txhim kho myocardial infarction (7.6%) tau txo qis piv rau kev siv tshuaj ib leeg (yuav luag 9% thiab 11% thaum noj pravastatin thiab tshuaj aspirin, feem).

Peb cov neeg nyeem tau siv Aterol ua tiav kom qis cov roj (cholesterol). Pom qhov nrov ntawm cov khoom no, peb tau txiav txim siab muab nws rau koj kom txaus siab.

Yog li, yog tias statins tau sau tseg nyob rau hmo ntuj ua ntej, uas yog, thaum lub sijhawm sib cais los ntawm kev noj lwm yam tshuaj, lub ntiaj teb kev kho mob hauv zej zog tam sim no txiav txim siab tias kev noj tshuaj sib xyaw ua ke hauv ib ntsiav tshuaj yog qhov zoo dua. Ntawm cov kev sib txuam no, cov tshuaj hu ua polypill yog tam sim no tau sim, tab sis lawv qhov kev siv ntau tseem nyob hauv kev txwv. Twb tau ua tiav cov tshuaj siv nrog kev sib txuam ntawm atorvastatin thiab amlodipine - caduet, duplexor.

Nrog theem siab ntawm cov roj (ntau dua li 7.4 mmol / l), kev siv cov tshuaj statins nrog cov tshuaj muaj peev xwm txo nws los ntawm lwm pab pawg - fibrates. Kev teem caij no tsuas yog ua los ntawm kws kho mob, ua tib zoo ntsuas kev pheej hmoo ntawm kev phiv.

Koj tsis tuaj yeem ua ke noj kev noj haus statins nrog kua txiv kab ntxwv qaub, vim nws muaj cov tshuaj uas ua rau cov metabolism hauv cov kab mob qis rau hauv lub cev thiab nce lawv cov kev xav hauv cov ntshav, uas yog fraught nrog txoj kev txhim kho cov kev phiv tshuaj lom.

Tsis tas li, koj yuav tsum tsis txhob noj cov tshuaj no nrog cawv, tshuaj tua kab mob, tshwj xeeb yog clarithromycin thiab erythromycin, vim tias qhov no tuaj yeem ua rau muaj kev phiv rau daim siab. Lwm cov tshuaj tua kab mob ua ke nrog cov tshuaj txo cov roj cholesterol kom zoo. Yuav kom ntsuam xyuas lub siab ua haujlwm, nws yog ib qho tsim nyog yuav tsum tau kuaj ntshav biochemical kuaj txhua peb lub hlis thiab txiav txim siab txog qib siab ntawm daim siab (AlAT, AsAT).

Kev phom sij thiab txiaj ntsig - Pros thiab Cons

Thaum noj tshuaj uas kws kho mob sau tseg, tus neeg mob xav txog qhov tseeb ntawm cov tshuaj.Kev noj cov tshuaj statins tsis muaj kev zam, tshwj xeeb yog vim qhov tseeb tias koj tuaj yeem hnov ​​feem ntau txog kev phom sij ntawm cov tshuaj no. Qhov kev pom no tuaj yeem tshem tawm, vim tias xyoo tsis ntev los no cov tshuaj kho tshiab tau tsim kho uas coj ntau cov txiaj ntsig dua li tsim kev puas tsuaj.

Cov txiaj ntsig ntawm kev noj cov statins

1. 40% yuav txo tau kev tuag nyob hauv thawj tsib xyoos,
2. 30% txo nyob rau hauv kev pheej hmoo ntawm mob hlab ntsha tawg thiab plawv nres,
3. Kev ua kom tau zoo - txo qis roj nrog qhov siv tas li los ntawm 45 - 55% ntawm thawj theem. Txhawm rau kom ntsuas qhov ua tau zoo, tus neeg mob yuav tsum kuaj ntshav txhua lub hlis txhawm rau cov cholesterol,
4. Kev Nyab Xeeb - noj cov tshuaj tshiab kawg ntawm statins hauv kev siv tshuaj tsis muaj tshuaj lom neeg tsis zoo rau tus neeg mob lub cev, thiab txoj kev pheej hmoo ntawm kev phiv yog tsawg heev. Ntau cov kev tshawb fawb uas tau ua lub sijhawm ntev los saib xyuas cov neeg mob uas tau noj cov tshuaj statins rau lub sijhawm ntev tau qhia tias lawv txoj kev siv yuav ua rau kev loj hlob ntawm hom 2 mob ntshav qab zib mellitus, mob qog mob cancer, cataracts, thiab puas hlwb. Txawm li cas los xij, qhov no tau pom zoo thiab ua pov thawj tias cov kabmob zoo li no tau pib vim lwm yam. Ntxiv mus, kev soj ntsuam hauv Denmark ntawm cov neeg mob uas muaj ntshav qab zib hom 2 mellitus uas twb muaj lawm txij li xyoo 1996 tau qhia tias qhov kev pheej hmoo ntawm kev tsim muaj cov ntshav qab zib muaj teeb meem xws li mob ntshav qab zib polyneuropathy, retinopathy raug txo los ntawm 34% thiab 40%, feem.
5. Coob tus naj npawb ntawm cov tshuaj yeeb yaj kiab nrog ib qho tshuaj yeeb yam hauv cov nqi sib txawv, uas pab xaiv cov tshuaj noj mus rau hauv tus account lub peev nyiaj ntawm tus neeg mob.

Qhov tsis zoo ntawm kev noj cov tshuaj statins

• Tus nqi siab ntawm qee qhov kev npaj ua ntej (Hla, rosucard, leskol forte). Hmoov zoo, qhov tsis zoo no tau yooj yim tshem tawm thaum hloov cov tshuaj nrog tib cov tshuaj muaj yees nrog tus qub pheej yig dua.

Yog lawm, xws li qhov zoo thiab cov txiaj ntsig tsis paub yuav tsum tau coj los ntawm tus neeg mob uas muaj qhov taw qhia rau kev nkag mus, yog tias nws xav tias nws muaj kev nyab xeeb los noj statins thiab ua tib zoo ntsuas qhov zoo thiab qhov tsis zoo.

Saib txog tshuaj

Cov npe ntawm cov tshuaj uas feem ntau siv rau cov neeg mob tau hais hauv lub rooj:

Lub npe ntawm cov tshuaj, cov ntsiab lus ntawm cov tshuaj nquag (mg)

Tus nqi kwv yees, rub

Kuv tiam SimvastatinVasilip (10, 20 lossis 40)Slovenia355 — 533 Simgal (10, 20 lossis 40)Czech koom pheej, Ixayees311 — 611 Simvakard (10, 20, 40)Czech koom pheej262 — 402 Simlo (10, 20, 40)Is Nrias teb256 — 348 Simvastatin (10, 20 lossis 40)Serbia, Russia72 — 177 PravastatinLipostat (10, 20)Russia, Tebchaws Asmeskas, Ltalis143 — 198 LovastatinHolletar (20)Slovenia323 Cardiostatin (20, 40)Lavxias244 — 368 Tiam II FluvastatinLeskol Forte (80)Switzerland, Spain2315 III tiam AtorvastatinLiptonorm (20)Is Nrias teb, Russia344 Liprimar (10, 20, 40, 80)Lub teb chaws Yelemees, USA, Ireland727 — 1160 Torvacard (10, 40)Czech koom pheej316 — 536 Atoris (10, 20, 30, 40)Slovenia, Russia318 — 541 Tulip (10, 20, 40)Slovenia, Sweden223 — 549 IV tiam RosuvastatinCrestor (5, 10, 20, 40)Russia, Great Britain, Lub Tebchaws Yelemees1134 – 1600 Rosucard (10, 20, 40)Czech koom pheej1200 — 1600 Rosulip (10, 20)Hungary629 – 913 Tevastor (5, 10, 20)Ixayees383 – 679 PitavastatinLivazo (1, 2, 4 mg)Ltalis2350

Txawm hais tias xws li kev nthuav dav dav hauv tus nqi ntawm statins, pheej yig dua analogues tsis ntau qis dua rau cov tshuaj kim. Yog li, yog tias tus neeg mob tsis tuaj yeem yuav cov tshuaj qub, nws muaj peev xwm hloov tau nws raws li kws kho mob tau sau nrog qhov zoo sib xws thiab pheej yig dua.

Kuv tuaj yeem txo qis kuv cov roj (cholesterol) uas tsis muaj tshuaj?

Hauv kev kho mob ntawm atherosclerosis raws li kev nthuav qhia cov roj "tsis zoo" hauv lub cev, thawj cov tshuaj yuav tsum pom zoo rau kev txhim kho kev ua neej, vim tias yog tias cov qib roj cholesterol tsis siab dhau (5.0 - 6.5 mmol / l), thiab kev pheej hmoo ntawm cov teeb meem mob plawv tseem qis, koj tuaj yeem sim normalize nws nrog kev pab los ntawm cov kev ntsuas:

• Khoom noj khoom haus kom zoo, lub koom haum ntawm kev noj mov nrog rau kev zam ntawm cov rog, cov zaub mov kib.Qhov nyiam muab yog muab rau cov tais diav hauv chav rhaub, hau, muab cub. Kev noj cov qe (yolks), nqaij ntawm cov rog ntau yam, offal (daim siab thiab lub raum), cov khoom noj muaj mis muaj tsawg. Nws yog ib qho tseem ceeb kom tsis suav cov khoom lag luam no, tab sis tsuas yog siv rau kev tsis txaus ntseeg raws li cov ntsiab lus ntawm kev noj zaub mov kom raug, txij li lub cev xav tau cov roj (cholesterol) los ua cov khoom tsim ntawm lub hlwb, daim siab, ntshav thiab lwm yam kabmob thiab cov ntaub so ntswg. Yog li, tsis txhob noj zaub mov nrog nws cov ntsiab lus txhua.
• Kev tawm dag zog lub cev tsim nyog rau lub xeev ntawm cov hlab plawv (taug kev, kev dhia paj paws, kev ua si hauv huab cua ntshiab, thiab lwm yam).
• Kev tsis kam ntawm qhov coj tsis zoo, raws li cov kws tshawb fawb tau ua pov thawj tias kev haus cawv thiab haus luam yeeb ua rau cov ntshav muaj roj.

Qee cov khoom noj muaj cov khoom tseem ceeb. Ntawm cov khoom lag luam no, qej thiab turmeric yog qhov kev kawm tshaj plaws. Ntses roj npaj muaj omega 3 fatty acids uas yog, uas pab cov roj metabolism hauv lub cev tsis zoo. Koj tuaj yeem nqa cov roj ntses, yuav hauv khw muag tshuaj, lossis koj tuaj yeem noj cov ntses tais ntses (trout, salmon, salmon, thiab lwm yam) ob peb zaug ib as thiv. Cov khoom noj muaj txiaj ntsig ntawm cov zaub fiber ntau, uas tau pom hauv txiv apples, carrots, cereals (oatmeal, barley) thiab legumes, tau txais tos.

Thaum tsis muaj cov nyhuv ntawm cov tshuaj tsis siv tshuaj, tus kws kho mob sau ib qho ntawm cov roj lipid.

Hauv kev xaus, Kuv xav nco ntsoov tias, txawm tias muaj kev ntshai ntawm cov neeg mob thiab lub tswv yim ntawm cov kev phom sij ntawm statins, lawv lub hom phiaj tsuas yog ua kom zoo rau cov kev mob atherosclerosis nyob deb nrog kev puas tsuaj rau cov hlab ntshav ntawm cov hlab ntshav, vim tias cov tshuaj no muaj sia nyob ntev. Yog tias koj muaj cov ntshav siab cov ntshav siab tsis muaj cov cim pib ntawm kev puas tsuaj rau vascular, tom qab ntawd koj yuav tsum noj zaub mov zoo, ua kom nquag plias, ua lub neej zoo, thiab yav tom ntej koj tsis tas yuav xav txog seb yuav noj cov tshuaj statins li cas.

Cov tshuaj kom txo cov roj cholesterol thiab ntxuav cov hlab ntshav

Ntau tus neeg muaj cov teeb meem kev noj qab haus huv uas cuam tshuam txog vascular mob. Yog li, koj yuav tsum paub dab tsi cov ntsiav tshuaj roj (cholesterol) muaj nyob thiab seb lawv ua haujlwm li cas.

Thaum tib neeg pom cov roj (cholesterol) hauv lawv cov ntshav, ntau tus neeg nug: "Cov tshuaj rau cov roj (cholesterol) puas ua haujlwm zoo lossis tsis tsim?" Nrog rau cov ntsiav tshuaj, kev noj haus thiab ua si lub cev yog qhov tseem ceeb. Yog li, nws yog qhov tseem ceeb kom paub tias hom tshuaj muaj roj uas txhaws roj tsawg? Yuav ua li cas lawv yuav tsum coj?

Cov cholesterol tsis zoo

Cov tshuaj tseem ceeb hauv tib neeg cov ntshav yog cov roj (cholesterol), uas nyob hauv cov yuag cell txhua qhov. Vitamin D thiab cov tshuaj tiv thaiv hormonal yog tsim los ntawm nws, thiab nws tseem ua rau tiv thaiv kab mob. Cov roj cholesterol ua rau txoj haujlwm zoo ntawm lub hlwb, daim siab, cov leeg thiab cov hlab ntaws. Txawm li cas los xij, los ntawm cov roj (cholesterol) siab, muaj kev phom sij vascular pathologies tshwm sim.

Peb cov neeg nyeem tau siv Aterol ua tiav kom qis cov roj (cholesterol). Pom qhov nrov ntawm cov khoom no, peb tau txiav txim siab muab nws rau koj kom txaus siab.

• tiv thaiv kom txhob tsub zuj zuj ntawm hydrocarbons,
• koom nrog kev tsim cov vascular hlwb,
• pab kev tsim cov kua tsib thiab cov tshuaj hormones tsim los ntawm cov qog adrenal,
• muab kev koom tes hauv cov metabolism,
• cais tawm cov hlab ntsha
• pab kom nqus cov vitamin D.

Ib qho enzyme yog tsim los ntawm daim siab mob hlwb, thiab cov protein hloov nws los ntawm ntshav. Raws li qhov no, lub ntsej muag saw, uas tom qab ntawd tig mus rau hauv lipoprotein cov lus ntawm cov khoom sib txawv.

Cov nyhuv ntawm lub cev yog nyob ntawm cov qauv ntawm cov khoom no. Yog tias qhov lipoproteins tsawg (LDL) tsawg, tam sim no ces cov quav hniav tawm rau hauv cov hlab, tom qab ntawd atherosclerosis tuaj yeem tshwm sim.Nrog siab impermeability (HDL), qhov hloov pauv ntawm cov roj cholesterol thiab cov kua tsib yog cov tshwm sim, uas ua rau txo qis kev pheej hmoo ntawm atherosclerosis.

Txhawm rau txiav txim siab txog qib ntawm cov tshuaj no, ib qhov kev kuaj ntshav biochemical tau ua tiav. Cov cai ntawm kev ntsuas muaj qhov sib txawv ntawm tus txiv neej thiab poj niam, lub hnub nyoog ntawm tus neeg kuj cuam tshuam tus nqi. Hauv qhov muaj zog ib nrab, txhawb cov roj cholesterol feem ntau pom.

Ib qho kev nce ntxiv ntawm qhov kev nqus ntawm lipoproteins tsawg kawg tom qab tsib caug xyoo tau sau tseg. Rau cov poj niam, qhov tshwm sim no yog xav thaum lub sij hawm lawm.

Vim li ntawd, cov kab mob loj pathological xws li mob ntshav ncig ntawm lub hlwb tuaj yeem tshwm sim, uas feem ntau ua rau myocardial infarction. Yog li, cov kws kho mob tau sau ntawv rau noj tshuaj kom pab txo cov rog.

Nrog kev mob plawv lossis mob hlab ntsha tawg, koj tsis tuaj yeem tso cai ua kom cov cholesterol nce siab. Txij li thaum kev rov ua dua ntawm kev txhim kho ntawm kev rov ua dua tshiab pathologies tuaj yeem nce ntxiv.

Dua li ntawm qhov tseeb tias cov rog hauv siab yog qhov txaus ntshai heev. Nws lub luag haujlwm hauv cov nyiaj nruab nrab yog loj heev, nws koom nrog txhua cov txheej txheem biochemical thiab xav tau rau lub neej ntawm lub cev. Yog li, tswj nws ib txwm yog qhov tseem ceeb, rau qhov no lawv siv tshuaj kho thiab ua lub neej kom raug.

Qhov ntsuas poob

Khoom noj khoom haus yog xaiv los ntawm kws kho mob, tab sis nws ua raws:

• txiav luam yeeb, haus luam yeeb,
• ntsev kom tsawg thiab cov zaub mov muaj roj,

• kev txwv cov tsiaj rog, nws yog qhov zoo dua rau noj cov zaub mov rog,
• zaub fiber ntau, cov carbohydrates complex thiab polyunsaturated acids yuav tsum muaj nyob hauv cov khoom noj.

Nws yog ib qho tsim nyog yuav tsum tau tso tseg cov khoom ntim muag thiab hnyuv ntxwm, ncuav qab zib, khoom qab zib, yob thiab muffins. Cov khoom noj muaj txiaj ntsig yuav tsis yog pab tshem tawm tus nqi siab xwb, tabsis tseem yuav txhim kho tus neeg lub neej kom zoo.

Nws tsim nyog teev tias 80% ntawm cov roj cholesterol yog tsim nyob rau hauv daim siab, thiab tshuav 20% ua rau noj zaub mov. Yog li, kev noj zaub mov kom raug thiab tsim nyog yuav pab tau nws li qub.

• poob phaus
• kev tawm dag zog txhua hnub
• taug qab cov calories

• muab mus rau qhov tsis zoo: haus dej cawv, haus luam yeeb,
• Zam kev ntxhov siab thiab poob siab.

Txo cov tshuaj no, koj tuaj yeem siv cov khoom lag luam raws li kev siv tshuaj ntsuab thiab kev siv tshuaj lom neeg biologically ntxiv. Omega-3 polyunsaturated fatty acids tiv thaiv plaques los ntawm kev nce thiab cov ntshav txhaws.

Muaj qee lub sijhawm thaum ua raws li kev noj zaub mov zoo, tso kev haus cawv thiab kev tawm dag zog ntev ntev tsis pab txo qis roj. Tom qab ntawd tus kws kho mob pom zoo kom haus cov tshuaj tshwj xeeb kom txo cov roj cholesterol.

Keeb kwm kev loj hlob

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Tshuaj tau nrhiav rau cov tshuaj uas txo cov roj (cholesterol) nyob rau qee lub sijhawm (txij li xyoo 1962). Txawm tias tom qab ntawd nws paub tias nws yog nws leej twg ua lub luag haujlwm tsis yog mob atherosclerosis nkaus xwb, tabsis tseem muaj kab mob rau lub plawv thiab mob plawv. Coob tus ntawm cov kev tshawb fawb nyob hauv tsev sim, ntau xyoo ntawm kev ua haujlwm, nyiaj ntau - nyob rau xyoo lawm txhua qhov no tsis muaj txiaj ntsig. Muaj ob qho teeb meem. Ua ntej, lawv ntshai hais tias cov tshuaj no yuav muaj kev phiv ntau, vim lipoproteins yog cov khoom siv rau lub tsev ntawm cov cell thiab yog cov neeg koom nrog kev tsim cov kua tsib kua qaub thiab cov tshuaj hormones steroid. Yog tias koj suppress lawv synthesis, tag nrho cov txheej txheem no yuav cuam tshuam. Thib ob, kev sim rau nas tsis tau muab txiaj ntsig, tsis muaj teeb meem dab tsi uas lawv tau sim.

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Txawm hais tias muaj kev nyuaj no los, tus kws tshawb fawb Nyijpooj Endo Akira tseem niaj hnub tshawb nrhiav cov tshuaj uas yuav cawm tau tib neeg los ntawm cov plahaum roj av, mob atherosclerosis, thiab lwm yam kab mob plawv. Nws cov kev tshawb fawb tau ntev txog xyoo 1971 txog 1976. 6,000 cov kev tshawb fawb thiab 5 xyoo - lub sijhawm ntau nws tau coj nws pab neeg los tsim thawj statin.

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Tus kws kho mob tshaj lij tau ua tiav sai thib ob ntawm kev cuam tshuam: nws muab tawm tias cov roj (cholesterol) yog ib qho muaj thiab muaj kev phom sij.Cov neeg sawv cev tau txwv cov synthesis ntawm ob, tab sis tus tsiaj lub cev tau them nyiaj rau nws qhov tsis muaj los ntawm nce thawj zaug, uas yog nws tau soj ntsuam thaum kuaj lub sijhawm. Thaum no tig tawm, nws muab tawm tias cov tshuaj yeej ua haujlwm thiab muaj kev cuam tshuam zoo heev.

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Thawj cov tshuaj yeeb tshuaj statin yog Kompaktin, uas yuav tsum tau tiv ntau qhov kev tawm tsam. Txawm hais tias nws cov hauj lwm zoo, nws tau pom tias yog carcinogenic thiab kaw lawm ntau lawm. Txawm li cas los xij, lub caij nyoog ntawm statins twb qhib, thiab tib neeg tsis tuaj yeem tso lawv. Txij li xyoo 80 ntawm lub xyoo pua XX, lawv tau coj cov nyiaj zoo rau cov tuam txhab lag luam kws tshuaj.

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Txawm li cas los xij, thawj qhov teeb meem tshwm sim uas tau tshwm sim thaum pib ntawm kev txhim kho cov tshuaj roj cholesterol tseem cuam tshuam txog tam sim no. Statins muaj qhov tuj ntawm kev phiv. Yog li, hauv kaum xyoo dhau los, kev txhim kho ntawm lwm cov lipid-txo cov tshuaj tseem tab tom pib.

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Cov ntaub ntawv dav dav

Yog tias pom muaj cov roj (cholesterol) hauv lub cev nce siab thaum kuaj thiab kuaj ntshav, tus kws kho mob tau sau ntawv rau cov tshuaj uas txo nws qis. Thiab feem ntau cov no feem ntau yog statins. Qhov seem lipid-txo tshuaj uas muaj cov tshuaj txawv txawv me ntsis, tsim nyob rau hauv xyoo tas los, muaj tsawg dua phiv. Tab sis lawv qhov kev ua tau zoo tsis tuav dej. Tom qab kawm tiav ntawm kev kho mob, lawv tsuas pom kho me ntsis ntawm kev mob ntawm cov neeg mob. Yog li no, cov kws kho mob uas xav pom qhov zoo li qub thiab kev nce qib tseem nyob ruaj khov rau tri-hydroxy-tri-methylglutaryl-CoA reductase inhibitors (lub npe scientific rau statins).

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Thaum sau tshuaj uas yuav txo cov roj khov rau lawv cov neeg mob, cov kws kho mob yuav tsum ceeb toom lawv ua ntej txog cov ntsiab lus hauv qab no:

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• txhawm rau kom txo cov roj (cholesterol) phem, statins qee zaum yuav tsum haus cawv tsis tu ncua, uas yog, tag nrho lub neej,
• tsis muaj qhov tsis sib xws nyob rau hauv cov nqe lus ntawm cov lus qhia rau lawv siv raug tso cai,
• cov kev mob tshwm sim tsis yog tsuas yog ntau - ntawm lawv muaj cov uas cuam tshuam rau kev nyab xeeb thiab txo lub neej zoo.

Yog li, txawm hais tias tus kws kho mob sau ntawv, tom qab nyeem daim ntawv teev cov kev mob tshwm sim, tsuas yog tus neeg mob txiav txim siab seb puas haus dej haus statins. Ob peb xyoos dhau los tsis muaj kev xaiv, vim tias lawv tsuas yog cov tshuaj nrog lipid-txo cov nyhuv. Tab sis cov tshuaj tam sim no muaj cov kev xaiv: fibrates, kev sib xyaw lipid hloov kho, kev sib txuas, lipid metabolism cov hloov kho, thiab lwm yam. Txawm li cas los xij, hais txog qhov ua tau zoo, lawv tau qis dua qis qis rau statins, uas los txog rau hnub no, txawm tias muaj kev thuam ntau, nws tseem yog cov thawj coj ntawm kev tawm tsam tsawg kawg lipoproteins (LDL).

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ATS kev faib tawm

Raws li rau kev faib tawm hais txog cov tshuaj muaj pes tsawg leeg tuaj yeem txo qis roj, yuav luag txhua yam ntawm cov khoom cua. Cov tshuaj ntsuab muaj xws li Lovastatin (kab mob hu ua oyster), Polyconazole (cov kab tsib muaj cawv), Guarem (hyacinth taum) thiab cov tshuaj noj kom tsis haum, qee lub sijhawm muab rau kev nqus ntawm atherosclerotic plaques, tab sis lawv tsis siv rau cov tshuaj lipid-txo qis.

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Daim ntawv tso tawm

Raws li daim ntawv tso tawm, tshuaj feem ntau yog tsim los ua ntsiav tshuaj lossis tshuaj ntsiav. Qee yog zoo li dej soluble hmoov. Nyob rau hauv daim ntawv ntawm kev txhaj tshuaj, nicotinic acid thiab kev tsim cov tshuaj tshiab Asmeskas Repatha (Repat) thiab Praluent (Pralent) yog cov kws kho, uas tseem tsis tau kov yeej txoj kev lag luam kws tshuaj.

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Raug raws lub npe: tri-hydroxy-tri-methylglutaryl-CoA reductase inhibitors.

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PBX code: C10AA.

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Lub rooj qhia cov npe ntawm cov khoom tseem ceeb ntawm statins thiab tshuaj tsim nyob rau lawv lub hauv paus, qhia lawv qhov ua tau zoo (los ntawm pes tsawg feem pua ​​lawv muaj peev xwm txo cov roj cholesterol):

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• Kuv: Lovastatin, Simvastatin, Pravastatin,
• II: fluvastatin,
• III: Atorvastatin, Cerivastatin,
• IV: Pitavastatin, rosuvastatin.

Ua haujlwm ntawm txhua cov tshuaj tom ntej yog los txhim kho lawv cov hauj lwm zoo thiab txo qhov pheej hmoo ntawm kev phiv thiab contraindications. Raws li nws muab tawm thaum kuaj mob, qhov no tsis ua haujlwm rau statins. Cov tuam txhab txhim kho tsis ua tiav cov hom phiaj no. Thiab txawm hais tias qhov txhais tau tias ntawm plaub, lub xeem tiam tseem tseem txaus ntshai ntawm kev muaj mob rau kev noj qab haus huv.

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• sai thiab zoo txo ​​cov roj cholesterol los ntawm 60%, txij li thaum lawv thaiv cov kev ua si ntawm cov enzymes (HMG-CoA reductase), uas ua rau muaj kev tsim cov lipoproteins uas tsim kev puas tsuaj,
• nce qhov concentration ntawm cov roj (cholesterol) zoo,
• txhim kho cov qauv ntawm lub siab nqaij pob, tiv thaiv nws txoj kev qaug zog,
• cia nws ua haujlwm ntau yam ntxiv,
• daws kev nyuaj siab
• txo txoj kev pheej hmoo ntawm ischemia los ntawm 15%, angina pectoris thiab mob plawv - los ntawm 25%,
• nce lub neej siab dua.

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• leeg ntshav siab
• atherosclerosis
• hypercholesterolemia,
• myocardial infarction
• Ischemic mob plawv,
• ACS
• kev tiv thaiv mob hlab ntsha tawg, plawv nres,
• leeg vauv thiab phais plawv.

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Txawm li cas los xij, raws li kev xyaum ua kom pom tseeb, nws raug nquahu kom siv cov statins tiv thaiv atherosclerosis thiab lwm yam CVDs rau cov tib neeg nruab nrab. Rau cov neeg laus dua (tom qab 60-70 xyoo), lawv tsis muaj txiaj ntsig thiab ua ntau dua qhov kev pab ntau dua.

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Sequestrants ntawm cov kua tsib kua qaub

PBX code: C10AC.

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• Colextran (Questran),
• Txog rau Kolesevelam (Colesevelam),
• Cholestipol, Colestipol (Colestipol),
• Cholestyramine, Colestyramin (Colestyramin).

Lawv muaj lub zog pharmacological zoo. Ua kom muaj zog sib xyaw ua ke nrog cov kua tsib kua qaub thiab tshem lawv. Lub cev tab tom muaj kev tsis txaus ntawm cov tshuaj uas muaj txiaj ntsig zoo rau nws txoj haujlwm tseem ceeb. Lub teeb liab sib luag yog xa mus rau daim siab, uas pib lawv lub zog ua ke. Txhawm rau ua qhov no, nws xav tau cov peev txheej loj ntawm cov cholesterol, uas nws siv. Yog li nws cov concentration hauv cov ntshav txo qis.

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Feem ntau muaj nyob rau hauv daim ntawv ntawm hmoov soluble hauv dej los yog kua txiv.

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Lawv tsis nqus rau hauv cov ntshav, yog li ntawd lawv kuj muaj kev nyab xeeb rau kev noj qab haus huv. Txawm li cas los xij, ntau tus kws kho mob tseem tawm tsam lawv vim qhov ua rau lawv txo qis cov kua tsib kua qaub, uas yog qhov tseem ceeb rau kev ua haujlwm ntawm feem ntau cov plab hnyuv siab raum thiab cov kab ke. Lub siab tsis tas yuav muaj sijhawm los coj los ua ke lawv cov nyiaj yuav tsum tau. Nws kuj tseem txo cov nqus folic acid nyob rau hauv cov hnyuv.

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Nws yuav tsum tau yug los rau hauv lub hlwb tias qib ntawm triglycerides nrog kev siv cov kua tsib acid sequestrants tsis txo. Tshwj xeeb rau qhov no, koj yuav tsum haus qee lwm yam tshuaj nyob rau hauv parallel.

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Kev npaj raws li Niacin

PBX code: C10AD.

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• Acipimox (Acipimox),.
• Txhuas nicotinate (Aluminium nicotinate),
• Niacin (Ac>Niacin

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• txo cov roj (cholesterol) phem thiab ua kom zoo ntxiv
• qhib fibrinolysis,
• txo cov mob thrombosis.

Cov kev kho mob yog ntev, nrog rau cov tshuaj maj mam nce zuj zus. Statins thiab fibrates yog contraindicated yuav siv ib txhij nrog cov tshuaj uas muaj nicotine (lawv txoj kev sib txuam ua pov thawj txoj kev txhim kho kev phiv).

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• mob ntshav qab zib mellitus
• mob gout
• mob plab
• mob rwj.

Ib teev ua ntej thiab ib teev tom qab noj niacin acid npaj, koj tsis tuaj yeem haus cov dej haus kub. Ntawm cov kev mob tshwm sim, muaj kev tsis xis nyob hauv plab, tab sis feem ntau qhov no tshwm sim nyob rau hauv muaj cov plab zom mov lossis mob txhab. Tam sim ntawd tom qab siv tas, lub ntsej muag ntawm lub ntsej muag yuav tau pib. Txhawm rau tshem tawm qhov kev ua txhaum no, cov tshuaj aspirin noj ib nrab ib teev ua ntej noj nws. Qee qhov sau hais txog dermatological teeb meem: khaus tawv nqaij, qhov tshwm sim ntawm qhov mob thiab mob erythema.

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Lwm yam tshuaj lipid-txo qis

PBX code: C10AX.

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Ezetimibum (Ezetimibum)

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Cov npe ua lag luam: Ezetrol, Ezetimibe, Lipobon, Otrio. Cov tshuaj yaj yeeb yog qhov tshiab tshiab. Nws cov pharmacological kev txiav txim siab txawv ntawm txoj ntsiab cai ntawm kev ua haujlwm ntawm lwm cov lipid-txo cov tshuaj.Nws yog concentrated nyob rau hauv txoj hnyuv thiab kev zom cov roj cholesterol. Qhov no ua rau nws txo qis hauv nws qhov kev nkag mus hauv lub siab. Yog li cov peev txheej ntawm lipoproteins raug txo qis, thiab lawv kev tshem tawm los ntawm cov ntshav nce ntxiv.

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Txoj kev tiv thaiv: kev mob siab dhau, kev mob rau daim siab, ua tub rog, cev xeeb tub.

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Qhov tshwm sim: mob raws plab, qaug zog, mob khaub thuas, mob ntsws, mob hlab pas sab saud, mob rau cov leeg ntshav, mob leeg. Nws tsis pom zoo kom ua ke nrog cyclosporine thiab lwm yam tshuaj lipid-txo qis.

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Policosanol (Policosanol)

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Qhov kawg roj cholesterol ua cov tshuaj txo qis. Tom qab kev sim tshuaj sim, nws pom tias muaj kev ua haujlwm siab txawm tias piv rau statins. Tib lub sijhawm, phiv yog pom ntau tsawg dua, thiab nws tsis txaus ntshai rau kev noj qab haus huv. Raws li txoj kev, nws txo qhov kev xav ntawm alanine aminotransferase thiab gamma glutamyl transpeptidase. Nws yog tsim ntawm lub hauv paus ntawm aliphatic cawv los ntawm kab tsib.

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Cov kev txwv tsis pub muaj: hnub nyoog txog 18 xyoo, cev xeeb tub, hypersensitivity, lactation.

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Phiv fab: xeev siab, raws plab.

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Kev sojntsuam

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Cov npe kev lag luam: Bifenabid, Fenbutol, Lesterol, Lipomal, Superlipid. Nws muaj cov nyhuv ob: nws txo cov synthesis ntawm cov cholesterol nyob rau hauv daim siab thiab nws nqus mus rau hauv cov ntshav los ntawm cov hnyuv. Nws tsis muaj kev cuam tshuam cov ncauj lus ntawm triglycerides. Muab tso rau nrog hypercholesterolemia, kev puas tsuaj rau lub hlab ntshav ntawm cov leeg. Cov tshuaj tiv thaiv: ventricular arrhythmias, cev xeeb tub, lactation. Ntawm cov kev mob tshwm sim, dyspepsia feem ntau sau tseg. Rho tawm ntawm Probucol yog tias nws txo ob qho kev phom sij thiab muaj txiaj ntsig cov roj (cholesterol). Ntau tus kuj tsis nyiam qhov xav tau kev kho mob ntev. Thawj qhov pom tau yog pom tsuas yog 2 lub hlis tom qab pib siv. Nws yuav tsum tau yug los hauv lub siab tias cov cuab yeej no tuaj yeem cuam tshuam cov txiaj ntsig ntawm qhov ntsuas hluav taws xob.

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Omega 3 Polyunsaturated Fatty Acids

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Cov npe kev lag luam ntawm cov khoom noj muaj zaub mov: Doppelgerz Omega, Omacor, Oceanol. Feem ntau muaj cov roj roj. Nws txo txoj kev pheej hmoo ntawm CVD, txo qis roj cholesterol, txuag koj ntawm kev nyuaj siab, thiab tshem tawm kev mob caj dab. Nrog rau kev siv tsis yog lossis siv ntev dhau los, nws tuaj yeem ua rau kev txhim kho ntawm pancreatitis.

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Dextrotyroxine (Dextrothyroxine)

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Nws yog tsiag ntawv los ntawm kev nqus hnyuv zoo. Nws yog tshuaj thaum nws tsim nyog los txo qhov transcendental concentration ntawm cov cholesterol. Ua ke, nws pab ua kom lub qog ua haujlwm lub cev qog. Ua kom nws muaj zog hypolipidemic ua ke nrog nicotine thiab clofibrate. Txoj kev kho yog kho nrog qhov noj tsawg kawg uas ua raws li los ntawm lawv nce. Cov kev mob tshwm sim: kam rau ua kom tau cov carbohydrates txo, bilirubin nce, leukopenia raug kuaj.

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Cov txheej txheem tiv thaiv: lub plawv tsis ua haujlwm, mob hnyav angina pectoris, mob ntshav qab zib mellitus.

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Cov lipid-txo cov tshuaj qhia hauv qab tus lej C10AX hauv ATS kuj muaj:

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• Benfluorex (Benfluorex) - raug txwv hauv ntau lub tebchaws vim tias nws cov tshuaj lom ntau,
• Magnesium pyridoxal, coenzyme B6 (Magnesium pyridoxal 5-phosphate glutamate),
• Meglutol (Miglutol),
• Thiadenol (Tiadenol).

Cov tshuaj siv Asmeskas Repatha (Repat) thiab Praluent (Praulent) cog lus tias yuav tso cov roj (cholesterol) li qub tsis pub dhau 2 zaug ib lim tiam. Txawm li cas los xij, kev kho mob hauv zej zog tsis tau maj nrawm los qhia lawv rau nws cov neeg mob, vim tias tseem muaj ntau qhov kev kuaj mob kom pom tseeb lawv cov hauj lwm zoo.

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Ua ke Lipid Modifiers

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Daim ntawv teev cov tau thiab nrov tshaj kev sib txuas:

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• Atorvastatin + Amlodipine,
• Lovastatin + Nicotine,
• Pravastatin + Cov tshuaj aspirin,
• Simvastatin + cov tshuaj aspirin,
• Simvastatin + Ezetimibe.

Cov tshuaj sib txuas ua ke zoo sib xws yog tsim kho los txhim kho lawv cov txiaj ntsig lipid-txo qis.

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Tsis yog txhua tus muaj kev txaus siab txog qhov yuav tsum tau ua kom qis cov roj (cholesterol) nrog cov tshuaj muaj hluavtaws zoo. Yog li, yog tias nws cov ntsiab lus tsis siab, cov kws kho mob tuaj yeem sau cov roj ntsha ntxiv nrog cov roj lipid. Lawv ua ntau dua maj mam thiab muaj qhov ntuj sib xyaw. Txawm li cas los xij, kev txiav txim siab ntawm lawv txoj kev siv, koj yuav tsum nco ntsoov tias lawv tsis yog tshuaj thiab tsis tuaj yeem tshem tawm cov kab mob loj uas cuam tshuam nrog lipoproteins. Lawv tsuas tuaj yeem hloov kho me ntsis kom paub tus mob.

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Qhov tseem ceeb Forte N

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Ua ke ua cov tshuaj hepatoprotective, uas suav nrog "phospholipids" tseem ceeb "(cholinophosphoric, linoleic thiab linolenic acids), pyridoxine, cyanocobalamin, nicotine, pantothene, riboflavin, tocopherol. Txhawb txoj kev rhuav tshem thiab tshem tawm cov roj "tsis zoo", txhim kho cov khoom muaj txiaj ntsig ntawm "zoo".

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Tykveol

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Muaj cov taub dag cov roj noob. Nws yog qhia nyob hauv kev kho mob cholecystitis, atherosclerosis, kab mob siab. Nws muaj cov kab mob hepatoprotective, tshuaj tua kab mob, tiv thaiv thiab choleretic.

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Guarem

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Kev npaj tshuaj ntsuab. Tshem tawm cov roj cholesterol thaum nws nyob hauv plab hnyuv, txo nws txoj kev nqus hauv cov ntshav. Nyob rau tib lub sijhawm, nws ua kom nrawm ntxiv rau kev nthuav dav ntawm cov kua tsib kua qaub, ua rau lub siab ua rau muaj zog. Txhawb kev qab los noj mov, pab rau qhov poob phaus. Muaj nyob rau hauv daim ntawv ntawm granules uas yaj hauv dej, kua txiv los yog mis nyuj. Nws zoo kawg nkaus ua ke nrog lwm cov tshuaj lipid-txo cov tshuaj. Cov kev mob tshwm sim: muaj ntau lub zog tshwm sim, xeev siab, mob plab tsis zoo, raws plab.

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Lipoic acid

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Nws yog ib qho antioxidant endogenous. Nws yog tawm hauv kev kho mob ntawm txoj hlab ntshav atherosclerosis.

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SievePren

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Nws yog tsim raws ntawm fir extract. Nws yog ib qho kev pabcuam hauv kev kho mob los ntawm kev mob ntshav siab, mob atherosclerosis. Lowers triglycerides thiab cov roj (cholesterol) tsis zoo.

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Cov vitamins

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Cov vitamins ntawm pab pawg B pab txhawm rau txo cov cholesterol: riboflavin (B2), pyridoxine (B6), folic acid (B9) thiab cobalamin (B12). Lipid-txo cov khoom muaj cov nicotine (B3) tau piav qhia saum toj no. Cov tshuaj no tuaj yeem siv tshuaj sib cais lossis sib xyaw nrog lwm tus. Kev pab zoo heev tuaj yeem yog cov vitamin ntxiv Benzaflavin (raws li riboflavin).

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Cov tshuaj roj hauv lub pluas mov kom tsawg yuav tsum tau siv nrog kev ceev faj vim qhov tsawg ntawm cov kev mob tshwm sim uas lawv tuaj yeem ua. Feem ntau cov feem ntau, lawv cov txiaj ntsig rau kev tiv thaiv thiab kev kho mob ntawm atherosclerosis thiab lwm yam CVDs tseem ceeb dua li qhov tshwm sim ntawm lawv siv. Txo txo ​​cov kev pheej hmoo, koj siv tsis tau lawv tus kheej, tsis muaj kws kho mob sau, thiab ua txhaum cov lus qhia.

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Cov Hom Tshuaj

Niaj hnub no, muaj ntau cov tshuaj uas siv rau cov roj (cholesterol) siab. Lawv muaj nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj thiab tsiav tshuaj. Tus kws kho mob, suav txog qhov xwm txheej ntawm tus neeg mob, xaiv txoj kev ua tau zoo tshaj plaws nrog kev mob tshwm sim tsawg kawg.

Cov tshuaj siv rau cov roj (cholesterol) hauv cov ntshav tau muab faib ua ntau hom.

1. Statins
2. Fibrates.
3. Cov tshuaj noj uas cuam tshuam nrog kev nqus ntawm lipoproteins tsawg ntom.
4. Nicotinic acid

Tsis muaj cov tshuaj zoo dua rau cov roj (cholesterol), hauv txhua hom tshuaj muaj ntau yam zoo thiab tsis zoo.

Cov txaj txaj yog suav tias feem ntau tshwm sim; lawv txo qis cov cholesterol. Lawv tsis ua mob rau daim siab, txawm tias muaj cov txiaj ntsig zoo ua rau nws.Txawm li cas los xij, yog tias ib tus neeg muaj kab mob siab rau siab, cov tshuaj no raug txwv rau kev siv, vim tias qhov mob hnyav dhau (daim siab ua haujlwm) tuaj yeem tshwm sim.

Daim ntawv teev cov npe nrov statins:

1. Simvastatin - Zokor, Vasilip.
2. Atorvastatin - Liprimar, Atoris.
3. Rosuvastatin - Crestor, Acorta.

Qhov muaj zog tshaj plaws yog cov nyiaj ntawm Atorvastatin thiab Rosuvastatin pawg, nws raug nquahu kom haus lawv ib hmos. Lawv tau xyaum tsis muaj kev mob tshwm sim, yog li lawv tuaj yeem kho txawm tias menyuam yaus.

Fibrate kev kho mob yog suav tias muaj tsawg. Lawv cuam tshuam rau cov lipid metabolism, tshwj xeeb hauv lipoproteins uas ntau ntau. Cov tshuaj no tau sau tseg hauv kev kawm. Fibrates tsis pub sib xyaw nrog statins. Lawv, zoo li txhua yam tshuaj, muaj cov kev mob tshwm sim, yog li thaum lawv tau muab tshuaj, cov yam ntxwv ntawm ib tug neeg raug coj mus rau hauv tus account.

Cov tshuaj tiv thaiv ntawm cov roj cholesterol (IAH) tsis tshua nrov, hauv khw muag tshuaj koj tuaj yeem yuav ib hom tshuaj (Ezetrol). Txo cov roj (cholesterol) yog ua tiav los ntawm kev txwv tsis pub nqus ntawm lipids los ntawm cov hnyuv. Cov tshuaj tsis muaj zog tshwm sim, thiab nws tuaj yeem ua ke nrog statins.

Nicotinic acid los yog niacin muab qhov txiaj ntsig zoo. Nws inhibits zus tau cov lipids. Txawm li cas los xij, nicotinic acid tsuas cuam tshuam cov roj ntsha, yog li tom qab qhov kawg ntawm chav kawm, microcirculation tau sau tseg. Raws li txoj cai, nrog kev tsis tu ncua ntawm cov nyiaj no, cov txiaj ntsig qis dua tshwm sim.

Tsis tas li, txhawm rau tswj kev zom zaub mov, cov kab mob kua tsib kua tsib yuav tsum tau noj. Qhov ua tau zoo tshaj plaws yog cholestyramine thiab colestipol. Lawv zoo li pwm cov kua tsib kua qaub thiab thauj lawv mus rau txoj hauv kev raws. Nrog cov tsis muaj lawv hauv lub cev, cov cholesterol nce ntxiv. Txawm li cas los xij, lawv tau muab tshuaj tsawg dua, vim tias lawv muaj ntau yam tshwm sim.

Polysaturated fatty acids nce oxidation hauv cov ntshav, thiaj li txo qis lipid. Lawv tsis muaj kev mob tshwm sim, tab sis cov nyhuv ntawm lawv tsis tshwm sim tam sim ntawd, tab sis tom qab ntev ntev.

Cov tshuaj pabcuam txo qis triglycerides hauv daim siab thiab qis dua LDL. Qhov tshwm sim ntawm kev kho mob ntev dua, yog li lawv tau raug txiav txim siab ntxiv rau cov tshuaj loj. Piv txwv, yog tias muaj cov khoom noj me me cog rau hauv tib neeg cov zaub mov noj, ces noj cov tshuaj fiber ntau hauv lub cev yuav ua rau qhov luv no.

Qhov zoo tshaj plaws rau txo cov roj ntshav siab yog:

1. Omega Forte.
2. Tykveol.
3. Lipoic acid.
4. Flaxseed roj.

Thaum muab tshuaj rau cov roj (cholesterol), feem ntau yuav tsum ua tib zoo saib:

• poj niam txiv neej thiab hnub nyoog
• muaj cov mob ntev thiab mob plawv,
• cwj pwm tsis zoo thiab kev ua neej.

Yog li, muaj cov npe dav dav rau cov tshuaj noj rau cov cholesterol. Nws yog ib qho tseem ceeb kom xaiv txoj kev kho kom zoo, suav txog txhua tus yam ntxwv ntawm tus neeg mob, tsuas yog hauv qhov no, qhov kev txo qis yuav tau txais txiaj ntsig.

Tsuas yog tus kws kho mob tuaj yeem sau cov tshuaj kom tsim nyog thiab lwm cov lus qhia uas tsim nyog.

Txog kev tiv thaiv, cov kws kho mob qhia tom qab 20 xyoo (ob zaug ib xyoo caum) los ua kev soj ntsuam los txiav txim seb puas muaj roj cholesterol. Txij li thaum lub hnub nyoog nyob hauv tib neeg ua lub neej tsis ncaj ncees, nws muaj peev xwm nce ntxiv. Yog tias tus neeg mob muaj kev pheej hmoo, ces qhov ntsuas yuav tsum tau kuaj xyuas tsis tu ncua, tsawg kawg 1-2 zaug hauv ib xyoos.

Cov tshuaj zoo tshaj plaws uas ua rau cov ntshav roj tsawg

Muaj ob peb txoj hauv kev los tiv thaiv kev rog siab. Ua ntej tshaj plaws, los ntawm kev ua raws kev noj haus thiab lwm txoj hauv kev, nrog rau kev siv cov tshuaj uas muaj cov nyhuv hypoglycemic.

Cov kws kho mob pom zoo tias koj yuav tsum tsis noj tshuaj rau koj tus kheej thiab muab txoj cai xaiv cov tshuaj zoo rau cov kws tshaj lij. Kev siv ntawm ib qho kev npaj tshuaj muaj peev xwm ua tau ntau yam kev mob tshwm sim, yog li ntawd kev coj tus kheej hauv qhov no yuav tsum tau caiv.

Tshuaj pab pawg

Nrog rau txoj hauv kev ua ke rau kev ua kom cov roj hauv lub cev, tus kws kho mob, ua ntej txhua yam, yuav muab cov kev kho cov neeg mob txoj kev noj haus zoo. Qhov thib ob theem yog kev sau tshuaj. Cov tshuaj roj uas txhaws hauv lub siab tuaj yeem tso ua ke raws li hauv qab no:

• statins
• fibroic acids
• tshuaj uas txhawb cov nyhuv choleretic,
• tshuaj ntsuab txo cov tshuaj zoo.

Cov neeg mob tsis tshua xav kom sim siv cov tshuaj no ntawm lawv tus kheej thiab kom tsis txhob tshuaj nws tus kheej. Thaum muab cov tshuaj sib xyaw ua ke nrog cov ntawv qhia ua neeg coob, yuav tsum muaj kws kho mob ntxiv. Kev phiv los ntawm kev noj tshuaj tuaj yeem tshwm sim qeeb qeeb, yog li txhua yam tshuaj yuav tsum ua raws li kev saib xyuas ntawm tus kws kho mob tas li. Yog tias muaj cov kabmob kis tau, nws tseem pom zoo kom qhia tus kws kho mob txog qhov no. Tag nrho cov no yuav pab kom tsis txhob muaj kev cuam tshuam ntxiv thiab ua rau muaj kev kho mob zoo.

Kev lees txais cov tshuaj ntawm ib qho ntawm cov pharmacological pawg yuav tsum nrog kev ua neej zoo, tsis lees paub tus cwj pwm phem thiab ua raws li kev ua lub cev. Ib qho kev cais yog khoom noj khoom haus. Los ntawm cov khoom noj yuav tsum tau muab tshem tawm kev siv cov kib, qab ntsev, ntsim. Dej qab zib: kua txiv tshiab tso cai. Nws yog ib qho tsim nyog kom yoo nqhis ntawm kev siv cov dej qab zib txhaws.

Cov tshuaj thawj zaug thiab pawg tseem ceeb ntawm cov tshuaj: statins. Cov tshuaj no pab txhawb kev tsim cov lipoproteins uas tsis muaj ntau thiab txo qis cov triglycerides hauv ntshav ntshav. Cov kev mob tshwm sim tuaj yeem yog los ntawm kev nce siab hauv cov tshuaj ntau dua thiab kev sib xyaw ntawm cov statins nrog qee pawg tshuaj. Pab pawg tshuaj no muaj ntau heev thiab suav nrog ntau dua 70 lub npe lag luam. Cov tshuaj yeeb dej caw hauv qhov kev npaj yuav sib txawv thiab tau faib raws tiam. Cov kev tivthaiv tseem ceeb yog cov tshuaj ua haujlwm hauv qab no: atorvastatin, rosurvastatin, simvastatin, lovastatin.

Ntawm cov kev mob tshwm sim los ntawm kev siv tshuaj ntawm cov pab pawg statin, cov xwm txheej hauv qab no yog qhov txawv: muaj teeb meem ntawm lub plab zom mov, uas tuaj yeem hais ua tus qauv, ua paug, xeev siab, thiab ntxiv rau, cov neeg mob yuav yws ntawm kev pw tsaug zog, kiv taub hau, thiab mob taub hau. Qhov tshwm sim ntawm kev mob tshwm sim yog qhov laj thawj los nrhiav tswv yim ntawm koj tus kws kho mob. Yav tom ntej, kev hloov kho ntau npaum lossis hloov cov tshuaj nrog rau qhov tsim nyog dua ib qho yuav tsum tau.

Nrog lub sijhawm ntev ntawm kev siv tshuaj ntawm cov pab pawg no, kev soj ntsuam tas li ntawm kev ua haujlwm ntawm lub raum yog xav tau. Raws li ntau cov kev tshawb fawb, kev siv cov statins tas li kuj ua rau muaj kev pheej hmoo ntawm kev muaj ntshav qab zib.

Kev txo cov roj hauv cov ntshav kuj tseem muaj ntau qhov kev tiv thaiv. Piv txwv li, lawv tsis pom zoo rau cov neeg uas muaj qhov tsis zoo ntawm kev ua haujlwm ntawm lub raum thiab nrog rau qee tus neeg tsis kam rau cov tshuaj ntawm cov tshuaj.

Cov neeg mob tuaj yeem sib tham nrog lawv tus kws kho mob cov khoom tshiab uas nyuam qhuav tshwm sim ntawm lub khw muag tshuaj. Qhov no tso cai rau koj xaiv cov tshuaj siv tau zoo tshaj plaws thiab nyab xeeb. Piv txwv li, tshuaj fluvastatin-raws li koom nrog kev ua tiav tshiab ntawm statins. Cov no yog cov tshuaj niaj hnub uas muaj qhov tsawg tsawg ntawm cov kev mob tshwm sim thiab muaj kev cuam tshuam cov tshuaj pharmacological sai. Tus kws tshuaj ntawm lub tsev muag tshuaj kuj tseem tuaj yeem qhia tus neeg mob txog cov tshuaj tshiab, zoo. Txawm li cas los xij, nws yuav tsum nco ntsoov tias kev teem sijhawm siv tshuaj kom txo qis roj tsuas yog tso cai los ntawm tus kws kho mob mus kawm, ua raws li tus neeg qhov yam ntxwv ntawm tus neeg mob.

Cov tshuaj Statins yog kho nrog kev ceev faj rau cov neeg laus.Qhov no yog vim qhov tseeb hais tias kev siv ntawm tib atorvastatin tuaj yeem pab txhawb kev nce siab hauv cov leeg nqaij. Tsis tas li, ntau tus neeg mob ntawm cov laus hnub nyoog sau txog kev pw tsaug zog, xeev tsis kam, thiab qab los noj mov.

Fibroic acid

Pab pawg thib ob loj suav nrog cov tshuaj uas txo cov roj cholesterol los ntawm cov pab pawg ntawm cov roj ntsha acids. Cov tshuaj pab pawg no tuaj yeem siv los ua cov tshuaj ntxiv ntawm cov tshuaj statin. Lub ntsej muag ntawm cov tshuaj ntawm fibroic acid pab pawg yog lawv lub peev xwm los sai sai txo cov qib triglycerides thiab qis lipoproteins tsawg, nrog rau ntau cov lipoproteins uas muaj tsawg kawg nkaus uas ua haujlwm zoo tua cov roj cholesterol. Cov lus qhia ntawm fibroic acids tuaj yeem khi rau cov kua tsib thiab thaiv qhov kev sib xyaw ntawm cov roj (cholesterol) los ntawm tib neeg lub cev.

Cov kws tshaj lij tau muab cov kev txheeb cais uas qhia tias kev noj tshuaj fibroic acid pab pawg 30-hnub txo qis tag nrho cov roj cholesterol tau 35-40%, triglycerides los ntawm 20%.

Feem ntau ntawm cov tshuaj tawm tom qab ob lub raum, yog li ntawd, yog tias muaj kev cuam tshuam ntawm kev coj ua haujlwm ntawm cov kabmob no, kev noj cov tshuaj fibroic tsis pom zoo. Cov kev mob tshwm sim thaum siv tshuaj los ntawm cov pab pawg cov fibroic acids cuam tshuam nrog qhov kev ua txhaum ntawm cov kev coj ua haujlwm zoo ntawm lub plab zom mov.

• Xws li nrog statins, cem quav, xeev siab thiab zawv plab yog tau. Txhua yam no yuav xav tau ntxiv, kho cov tsos mob siv lwm pawg tshuaj (piv txwv li, omeprazole, uas tiv thaiv lub plab hnyuv phab ntsa).
• Tsis tas li ntawd, qhov cuam tshuam tsis zoo ntawm cov kab mob plawv tau sau tseg - nws nce qhov kev pheej hmoo ntawm cov hlab ntsha mus rau ntshav.
• Kev tsim kho tau ntawm kev fab tshuaj: liab ntawm daim tawv nqaij, khaus, tawm pob.
• Muaj qee kis, cov neeg mob yws yws mob taub hau thiab txo qis libido.

Yog tias ib qho ntawm cov kev mob tshwm sim no tshwm sim, nws raug nquahu kom cov neeg mob tsum tsis siv tshuaj ib ntus thiab nrhiav tswv yim kho mob.

Cholagogue thiab tshuaj

Txo cov roj uas txhaws nrog cov tshuaj uas muaj cov choleretic muaj qhov ntxiv, muaj txiaj ntsig zoo rau qhov ib txwm ua ntawm triglycerides thiab lipoproteins tsawg ntom. Lub hauv paus ntsiab lus ntawm kev ua ntawm cov tshuaj choleretic yog qhov yooj yim: lawv khi cov roj (cholesterol) ntau dhau thiab maj mam tshem tawm ntawm lub cev. Npaj rau ntawm pab pawg no zoo zam. Ntawm qhov mob tshwm sim hauv qee kis, muaj ua xua thiab mob hauv plab.

Muaj cov tshuaj tshwj xeeb uas txo qis cov roj cholesterol ua kom ncaj qha rau hauv txoj hnyuv. Cov no suav nrog: Xenical, Orlistat, Ezetrol. Cov tshuaj no yuav dhau los ua cov neeg pab tsis tau thaum lub sijhawm cov cholesterol mus hauv lub cev los ntawm cov khoom noj. Cov kev mob tshwm sim thaum siv cov tshuaj no yog qhov tsis zoo heev: nquag yoo kom tso quav, uas muaj kev tso tawm nrog cov rog, tshaj tawm hauv plab, kev fab tshuaj. Tawm tsam keeb kwm yav dhau los ntawm kev noj tshuaj pab pawg no, kev noj zaub mov kom nruj yog qhov ua tiav nrog kev tshem tawm cov rog rog.

Cov hau kev ntxiv

Kev siv cov lipoic acid thiab tsiav tshuaj, uas suav nrog omega-3, omega-6 thiab omega-9 Cheebtsam, nrog rau cov tshuaj hauv qab no, yog tshuaj ntsuab npaj rau txo cov roj:

• Qij tshuaj siav qhuav kuj tseem siv tau ua kev kho mob ntxiv rau hypercholesterolemia.
• Cov txiaj ntsig zoo kuj yog cov tshuaj uas suav nrog cov noob taub dag. Piv txwv li, cov tshuaj Tykveol pab tswj hwm cov lipid metabolism thiab txo cov roj triglycerides.
• Cov tshuaj ntsuab kho mob, uas suav cov rho tawm ntawm fir, hawthorn, linden thiab lwm yam phytoelements, kuj tseem siv tau rau hauv txoj kev kho mob ua cov roj (cholesterol) siab.
• Kev siv cov lipoic acid pab tiv thaiv kev txhim kho atherosclerosis, kab mob ntawm cov hlab plawv thiab, ntawm chav kawm, tswj cov qib roj cholesterol.

Kev npaj raws li siv tshuaj ntsuab muaj tsawg qhov tshwm sim tsawg dua thiab muaj qhov ua kom zoo dua li cov statins lossis fibroic acids. Txawm li cas los xij, qhov ua tau zoo ntawm cov nroj tsuag cov ntsiab lus thiab tus nqi ntawm lawv cov txiaj ntsig rau kev ua kom cov cholesterol yog qhov qis qis dua rau cov tshuaj sib txuas ntawm cov tshuaj fibrates lossis statins. Yog li no, thaum yuav tsum tau txo cov roj (cholesterol) sai, yuav tsum tau siv cov qij taum lossis cov roj ntses tuaj yeem ua kev kho ntxiv.

Kev siv ntxiv ntawm cov vitamin complexes, uas suav nrog cov vitamins B thiab nicotinic acid, kuj tseem siv nyob rau hauv kev sib ntaus cov tiv thaiv kabmob siab. Kev siv cov tshuaj vitamin txo cov roj hauv cov ntshav tso cai rau koj los tswj cov lipid metabolism, thiab nicotinic thiab folic acid normalizes qib triglycerides.

Npaj rau txo qis roj ua sai sai thiab muaj txiaj ntsig. Ua raws li cov tshuaj kho mob thiab txhua tus kws tsim cov lus pom zoo, kev kho tshuaj yuav muaj kev vam meej thiab muaj qhov tshwm sim tsawg kawg nkaus. Siv qee yam tshuaj noj uas ua rau txo qis roj cholesterol lossis tsis yog qhov kev xaiv tus kheej rau txhua tus neeg mob. Txawm li cas los xij, ib qho yuav tsum coj mus rau hauv tus account qhov tseeb tias txhawb cov qib roj cholesterol txaus ntshai kom muaj kev cuam tshuam ntawm cov hlab plawv cov ntshav, tuaj yeem ua rau mob stroke, mob plawv thiab mob atherosclerosis. Kev saib xyuas tus cwj pwm rau koj lub cev yog tus yuam sij rau lub neej ntev thiab kev noj qab nyob zoo.

Lub ntsiab tseem ceeb ntawm cov tshuaj

Ua ntej tshaj plaws, lipid-txo cov tshuaj yuav tsum tau sau tseg. Cov no suav nrog:

1. fibrates
2. statins
3. tshuaj anion txauv tshuaj thiab cov resins uas txo qhov nqus ntawm cov roj hauv plab hnyuv,
4. nicotinic acid
5. probucol.

Raws li cov txheej txheem ntawm kev txiav txim, cov tshuaj no tuaj yeem faib ua ntau pawg neeg:

• tshuaj uas tiv thaiv cov khoom ntawm cov roj uas txhaws tsis tshua muaj kabmob (nws tseem hu ua qhov tsis zoo): statins, fibrates, nicotinic acid, probucol, benzaflavin,
• cov neeg sawv cev uas tuaj yeem ua rau qeeb nqus ntawm cov roj uas txhaws taus: guar, cov kab mob sib txuas ntawm cov kua tsib kua qaub,
• rog metabolism kho uas ua rau kom cov roj cholesterol siab: lipostabil, qhov tseem ceeb.

Sequestrants ntawm cov kua tsib kua qaub

Cov tshuaj uas cov kua tsib kua tsib yog feem ntau hu ua anion txauv resins. Sai li cov tshuaj no nkag mus rau hauv txoj hnyuv, cov acids raug ntes thiab tom qab tshem tawm los ntawm lub cev.

Cov tom kawg teb rau cov txheej txheem no los ntawm kev ua kom muaj kev sib txuas ntawm cov kua tsib kua qaub tshiab los ntawm cov khw muag roj uas txhaws tawm. Cov roj (cholesterol) yog txhawm rau los ntawm cov ntshav, uas pab txo nws.

Kev lag luam kws tshuaj muaj cov tshuaj cholestyramine hmoov, thiab colestipol, kom txo cov ntshav cov roj hauv cov ntshav. Lawv yuav siv tau nyob rau hauv 2-4 koob tshuaj, nrog lub obligatory ua ntej dilution nrog dej.

Anion-pauv cov roj hmab tsis tuaj yeem nkag mus rau hauv cov ntshav thiab "ua haujlwm" tsuas yog hauv plab hnyuv lumen. Vim tias qhov tshwj xeeb no, tshuaj tsis muaj peev xwm muaj kev cuam tshuam tsis zoo rau lub cev.

Cov kev mob tshwm sim tuaj yeem suav nrog:

Yog tias tso tawm cov kua tsib cov kua qaub hauv cov dej ntau ntau hauv lub sijhawm ntev, tom qab ntawv qhov no yuav muaj kev ua txhaum ntawm kev nqus ntawm qee cov vitamins, ntxiv rau cov kua tsib.

Cov tshuaj hauv cov pab pawg no txo ​​cov kev xav txog cov tshuaj phem, thiab qhov muaj cov triglycerides hauv cov ntshav yuav tseem zoo li qub.

Cov Roj Cholesterol Tuaj Tsis Ua Phem

Vim tias maj mam nqus cov cholesterol los ntawm cov khoom noj, pawg tshuaj no tuaj yeem txo nws cov concentration. Qhov ua tau hauj lwm zoo tshaj yuav yog cov guar. Cov zaub mov ntxiv no ua kom nyab xeeb thiab muab tau los ntawm cov noob ntawm hyacinth taum. Cov sib xyaw ua ke ntawm cov khoom lag luam suav nrog polysaccharide, uas, hauv kev sib cuag nrog cov kua, hloov mus rau hauv jelly.

Guarem muaj peev xwm kho cov neeg zom cov roj (cholesterol) cov roj (cholesterol) los ntawm cov hnyuv phab ntsa. Tsis tas li ntawd, cov yeeb tshuaj:

• leeb kom tshem tawm ntawm cov kua tsib kua qaub,
• dulls lub qab los noj mov
• pab txo cov khoom noj noj kom tsawg.

Qhov nqus tshuaj nqus no yog nyob rau hauv daim ntawv ntawm granules los muab ntxiv rau hauv cov dej haus. Kev siv cov tshuaj tuaj yeem yooj yim ua ke nrog lwm txoj kev.

Thaum siv, cov kev mob tshwm sim kuj tseem muaj peev xwm ua tau, piv txwv, txhaws qhov quav, mob hauv cov hnyuv, xeev siab thiab tsam plab. Cov tsos mob no yog me thiab tsis tshua muaj tshwm sim. Txawm tias tsis muaj txoj kev kho, lawv dhau los sai sai, thaum muaj kev cuam tshuam hauv lub cev cov ntshav hauv cov ntshav siab.

Nicotinic Acid

Nicotinic acid thiab tag nrho nws cov derivatives, piv txwv li:

hauv cov ntsiab lus tseem ceeb, lawv yog cov vitamins B. Cov tshuaj no txo ​​cov roj cholesterol tsawg dua thiab tseem ua rau cov kab mob fibrinolysis, uas pab ntxiv txo cov kev pheej hmoo ntawm thrombosis. Cov txhais tau tias zoo dua li lwm cov lipid-txo cov tshuaj nce cov ntsiab lus ntawm cov roj cholesterol zoo hauv cov ntshav ntawm tus neeg mob.

Kev kho nrog nicotinic acid yuav siv sij hawm ntev nrog kev nce ntxiv hauv cov tshuaj. Tom qab noj cov kev npaj, ua ntej uas koj yuav tsum tsis txhob haus dej kub, tshwj xeeb tshaj yog kasfes ntuj.

Niacin tuaj yeem ua rau thaj chaw ntawm lub plab, uas tsis suav nrog nws siv yog tias mob rau sab hauv thiab mob caj dab. Feem ntau ntawm cov neeg mob, liab lub ntsej muag yuav pom thaum pib kho, txawm li cas los xij, cov tsos mob no ploj mus ntev. Txhawm rau tiv thaiv liab, koj yuav tsum haus 325 mg ntawm tshuaj aspirin ib nrab ib teev ua ntej siv cov tshuaj.

Lub ntsiab contraindications rau nicotinic acid muaj xws li:

• kab mob siab
• mob gout
• lub siab tuaj cuam tshuam tuaj.

Muaj tshuaj uas tuaj yeem tsim cov kev mob tshwm sim tsawg kawg nkaus thiab kav ntev dua - qhov no yog enduracin.

Probucol tsis cuam tshuam rau triglycerides, tab sis nws kuj kho qhov sib npaug ntawm cov roj ntsha zoo thiab cov kab mob hauv cov ntshav. Cov ntsiav tshuaj thawb qhov peroxidation ntawm cov rog thiab tso tawm kom pom lub zog los tiv thaiv atherosclerotic, cuam tshuam rau txo qis hauv cov roj cholesterol.

Qhov tshwm sim ntawm kev kho nrog Probucol tuaj yeem tau txais tom qab 2 lub hlis thiab tuaj yeem mus txog 6 lub hlis tom qab kev tso tseg ntawm nws txoj kev siv. Cov cuab yeej tuaj yeem ua ke zoo kawg nkaus nrog lwm cov tshuaj uas txo cov roj (cholesterol).

Thaum lub sij hawm kho, kev txuas ntxiv ntawm kev ntsuas lub plawv ntu thiab kev txhim kho lub plawv kev ntxhov siab tuaj yeem pom. Txhawm rau tiv thaiv cov mob no, nws yog ib qho tsim nyog yuav tsum yauv siv hluav taws xob tsawg kawg 1 zaug hauv 6 lub hlis.

Probucol tsis tuaj yeem raug kho nyob rau tib lub sijhawm xws li cordarone.

Sab kev mob tshwm sim ntawm lub cev suav nrog kev mob kev mob plab hauv plab, xeev siab thiab zawv plab.

Cov tshuaj yuav tsum tsis txhob noj nrog:

• ventricular arrhythmias,
• nquag ntu ntawm myocardial ischemia,
• qis theem ntawm HDL.

Fibrates tuaj yeem ua tiav cov qib ntawm triglycerides, nrog rau cov ntsiab lus ntawm LDL thiab VLDL. Lawv tuaj yeem siv nrog cov kabmob hypertriglyceridemia. Cov nrov tshaj plaws tuaj yeem raug hu ua cov ntsiav tshuaj:

• gemfibrozil (lopid, gevilon),
• fenofibrate (Tipantil 200 M, Tricor, Exlip),
• cyprofibrate (lipanor),
• choline fenofibrate (trilipix).

Qhov tsis zoo tshwm sim ntawm kev noj tau tuaj yeem raug mob rau qhov mob hauv cov leeg, xeev siab thiab mob hauv lub plab plab. Fibrates tuaj yeem nce ntxiv qhov tshwm sim ntawm lub raum pob zeb thiab lub zais zis. Tsis tshua muaj txiaj ntsig txaus, kev txwv tsis pub hematopoiesis tuaj yeem pom.

Cov tshuaj no tsis tuaj yeem raug sau tseg rau cov kab mob ntawm lub raum, zais zis thiab ntshav teeb meem.

Statins yog cov tshuaj txaws txo cov roj (cholesterol) zoo tshaj plaws. Lawv muaj peev xwm los thaiv cov enzyme tshwj xeeb uas teb rau kev tsim cov roj ntsha zoo li hauv lub siab, thaum txo nws cov concentration hauv cov ntshav. Nyob rau tib lub sijhawm, tus naj npawb ntawm LDL receptors yog nce, uas muab lub zog cuam tshuam rau lub nrawm rho tawm ntawm cov roj cholesterol tsawg.

Raws li txoj cai, cov tshuaj hauv qab no tau sau tseg:

• simvastatin (vasilip, zokor, aries, simvageksal, simvakard, simvakor, simvastatin, simvastol, simvor, simlo, sincard, holvasim),
• lovastatin (cardiostatin, choletar),
• pravastatin
• atorvastatin (anvistat, atocor, atomax, ator, atorvox, atoris, vazator, lipoford, lypimar, liptonorm, novostat, torvazin, torvakard, tulip),
• rosuvastatin (akorta, ntoo khaub lig, mertenil, rosart, rosistark, rosucard, rosulip, roxera, xeb pov tseg, tevastor),
• pitavastatin (livazo),
• fluvastatin (leskol).

Simvastatin, nrog rau lovastatin, yog tsim los ntawm cov hu ua fungi. Cov tshuaj zoo sib xws rau cov ntsiav tshuaj roj siab ntev hloov mus rau hauv cov tshuaj metabolites. Pravastatin yog ib qho fungal derivative uas yog nws tus kheej yog cov tshuaj nquag.

Statins tuaj yeem pom zoo ib zaug txhua hmo. Qhov kev cai tswj hwm kev kho mob no tau piav qhia los ntawm qhov tseeb tias qhov siab tshaj plaws ntawm kev tsim cov ntshav cholesterol tshwm sim thaum tsaus ntuj. Sij hawm dhau mus, qhov kev txhaj tshuaj ntawm statins tuaj yeem nce ntxiv, thiab nws cov txiaj ntsig yuav tiav tom qab thawj ob peb hnub ntawm kev tswj hwm, nce mus txog qhov siab kawg nkaus hauv ib hlis.

Statins muaj kev nyab xeeb txaus rau tib neeg, tab sis nws yog qhov tseem ceeb heev kom tsis txhob siv cov koob tshuaj loj, tshwj xeeb tshaj yog siv nrog fibrates, uas yog fraught nrog daim siab mob.

Qee tus neeg mob yuav muaj cov leeg tsis muaj zog thiab mob hauv lub cev. Muaj qee kis, mob plab, cem quav, xeev siab, nrog rau qhov ua tiav ntawm kev tsis qab los noj mov, pw tsaug zog thiab mob taub hau tau sau tseg.

Cov tshuaj no kom txo cov roj (cholesterol) tsis muaj peev xwm cuam tshuam rau cov plhaws carbohydrate thiab purine, uas tso cai rau lawv siv rau ntau qib kev rog, mob gout thiab ntshav qab zib. Nco ntsoov tias yog tias cov roj (cholesterol) siab pom thaum lub cev xeeb tub, nws yuav tsum sab laj nrog kws kho mob nrog cov tshuaj.

Yog tias peb xav txog cov kev kho mob ib txwm, ces cov tshuaj statins tuaj yeem txuas nrog kev kho mob ntawm atherosclerosis li kev kho mob monotherapy lossis nrog rau lwm cov tshuaj.

Pharmacology muaj cov kev sib txuas ua ke npaj raws li:

1. lovastatin thiab nicotinic acid,
2. ezetimibe thiab simvastatin,
3. pravastatin thiab fenofibrate,
4. rosuvastatin thiab ezetimibe.

Kev hloov pauv ntawm statins thiab acetylsalicylic acid, atorvastatin thiab amlodipine yuav raug tso tawm.

Kev siv cov tshuaj npaj tau ua tsis yog tsuas yog muaj txiaj ntsig ntau dua txog kev txuag nyiaj, tab sis kuj ua rau kev cuam tshuam tsawg heev ntawm kev phiv.

Qhov twg yog qhov zoo thiab pheej yig?

Hais txog kev tswj hwm kev noj qab haus huv lossis txuag lub neej, tus nqi ntawm cov tshuaj yuav tsum tsis yog tib qho kev xaiv, txawm hais tias cov tshuaj muaj roj cholesterol pheej yig tuaj yeem zoo heev. Txhua yam nws yog nyob ntawm tus neeg raug mob ntawm lub cev mus rau cov khoom xyaw nquag ntawm cov ntsiav tshuaj thiab ntawm qhov ntsuas kev puas tsuaj rau cov kabmob los ntawm hypercholesterolemia (nce cov roj cholesterol). Niaj hnub no, hauv kev kho cov mob no, feem ntau 2 hom tshuaj siv yog:

• statins (HMG-CoA reductase inhibitors),
• fibrates (derivatives ntawm fibroic acid).

Hauv chav kawm ntawm statins, cov ntsiav tshuaj roj (cholesterol) uas muaj cov tshuaj yeeb dej caw yog siv:

• atorvastatin,
• lovastatin
• pitavastatin
• pravastatin
• rosuvastatin,
• simvastatin
• fluvastatin.

Cov pawg ntawm fibrates yog sawv cev los ntawm cov tshuaj nquag:

• bezafibrat,
• fenofibrate
• choline fenofibrate,
• ciprofibrate.

Ntawm cov tshuaj ntawm cov pab pawg no, koj tuaj yeem xaiv cov tshuaj pheej yig rau cov roj (cholesterol). Cov npe kev lag luam ntawm cov tshuaj yuav txawv ntawm lub hauv paus (cov tshuaj ua kom muaj zog), yog li ntawd nws yog qhov zoo dua rau kev tso npe xaiv cov tshuaj rau kws kho mob.

Cov tshuaj uas nrov tshaj plaws

Sau cov npe ntawm cov tshuaj zoo tshaj plaws

Thaum ib tus neeg sim nrhiav cov npe npe ntawm cov tshuaj zoo heev, nws yuav tsum tsis txhob mus rau lub tsev muag tshuaj, tab sis mus rau tom qhov chaw kho mob thiab ua ntej kom paub tseeb tias nws xav tau cov tshuaj kom muaj cov cholesterol.

Qhov zoo tshaj plaws feem ntau muaj xws li cov tshuaj tsim los rau hauv kev txiav txim siab txhua qhov tsis txhua ntawm cov tshuaj yav dhau los uas tau tshwm sim hauv kev kho mob. Peb tab tom tham txog kev siv tshuaj kho tshiab ntawm cov neeg txuas ntxiv, lawv yog nyob ntawm statins, thiab hauv cov pab pawg ntawm cov fibrates, thiab lwm yam tshuaj. Ntawm chav kawm, tus nqi ntawm cov tshuaj no yog ntau dua li tus nqi ntawm cov "zoo tib yam" cov ntsiav tshuaj roj. Peb nthuav qhia cov npe zoo tshaj plaws (kim) lipid-txo cov tshuaj hauv lub rooj.

Statins rau kev txo qis LDL hauv cov ntshav

Raws li tuaj yeem pom los ntawm lub rooj, statins sawv cev rau pawg ntau tshaj plaws ntawm cov tshuaj los txo cov ntshav roj hauv lub cev. Txawm hais tias cov chav kawm ntawm cov tshuaj no tseem tsis ua rau muaj kev ntseeg siab rau cov neeg mob lossis cov kws kho mob vim tias muaj kev pheej cuam tshuam tshwm sim tsis zoo thaum siv tshuaj kho. Cov lus qhia rau cov tshuaj no muaj "kilometer" cov npe ntawm contraindications, ceeb toom thiab muaj kev pheej hmoo thaum noj. Tias yog vim li cas nws tsim nyog paub koj tus kheej nrog cov tshuaj lipid-txo qis hauv ntau yam.

Txhawm rau kom cov neeg nyeem nkag siab qhov teev ntawm pharmacological kev txhim kho hauv qhov kev taw qhia no, peb teev cia cov piv txwv nram qab no:

• nyob rau hauv pab pawg ntawm statins muaj 7 lub zog tseem ceeb tshuaj (lawv cov npe raug nthuav tawm saum toj no),
• muaj 88 cov cim lag luam ntawm statin tshuaj,
• lub zej zog ntawm tag nrho cov tshuaj ntawm cov pab pawg ntawm cov sib txawv no yog ntau tshaj 3,500 npe.

Nws yog qhov tseeb tias nws tsis yooj yim sua kom sau tag nrho cov npe, yog li peb yuav tsom mus rau cov neeg nyiam tshaj plaws.

Atorvastatin

Kev noj tshuaj rau cov roj (cholesterol) kom tsawg dua Atorvasatin muaj los ntawm ntau lub tuam ntxhab hauv ntau lub tebchaws. Cov tshuaj muaj zog yog atorvastatin calcium, uas zwm rau cov tshuaj pharmacotherapeutic pawg ntawm cov tshuaj lipid-txo cov tshuaj, xaiv cov tshuaj tiv thaiv ntawm HMG-CoA reductase. Nws cov nyhuv yog txo qib uas qis thiab qis ceev lipoproteins (LDL thiab VLDL), triglycerides thiab apolipoprotein B los ntawm inhibiting cov synthesis ntawm cov roj hauv lub siab. Tsis tas li ntawd, nyob rau hauv kev cuam tshuam ntawm atorvastatin, theem ntawm HDL - high-density lipoproteins nce luv luv.

Cov pab pawg ntawm cov chaw lag luam tshuaj KRKA thiab lawv cov ceg tsim tshuaj ntsiav rau cov roj Atoris nrog cov tshuaj nquag atorvastatin. Zoo li feem ntau cov statins, lawv muaj pov thawj muaj peev xwm txo qis kev pheej hmoo ntawm cov teeb meem xws li mob angina pectoris thiab mob plawv (26 thiab 16%, feem). Lawv thaiv ntawm kev ua haujlwm ntawm macrophages, tiv thaiv qhov tawg ntawm atherosclerotic plaques.

Contraindicated rau cov xwm txheej txheem rau statins:

• nrog rau cov kab mob siab thiab nce ntxiv hauv transaminases ntau dua 3 zaug los ntawm qib siab kawg ntawm kev cai,
• lactase deficiency thiab lwm yam mob cuam tshuam nrog kev tsis haum lactose,
• nrog cov leeg pob txha pathologies,
• cev xeeb tub thiab lactation,
• tsis tau muaj 18 xyoo.

Cov ntsiav tshuaj muaj nyob rau hauv qhov tshuaj ntawm 30, 60 thiab 80 mg. Tsos - cov tshuaj dawb convex ntawm ib puag ncig lossis kheej kheej cov duab.

Txhawm rau txo qhov kev nyeem ntawm cov roj (cholesterol) thiab txo qhov kev pheej hmoo ntawm cov hlab plawv, raws li cov lus qhia rau kev siv, cov tshuaj Novostat kuj tseem npaj siab (thov ceeb toom - tsis yog Novostatin). Qee zaum cov neeg tuaj saib xyuas cov khw muag tshuaj (tshwj xeeb yog cov neeg nrhiav tshuaj kom txo cov roj (cholesterol) raws li kev txheeb xyuas ntawm cov phooj ywg) ua rau lub npe ntawm cov tshuaj nrog lwm cov tshuaj thiab hais kom lawv muab cov tshuaj no rau Novostatin. Cov neeg mob tsis muaj hmoo no yuav tsum tsis txhob xav tsis thoob yog tias, es tsis txhob siv cov lipid-txo qis tus neeg sawv cev, lawv tau muab rau cov tshuaj tua kab mob Nystatin.

Novostat yog raws li atorvastatin thiab muaj tag nrho cov chaw muag tshuaj ntawm cov tshuaj yeeb tshuaj no.

Lub tuam txhab Czech lub tuam txhab Zentiva ua cov atorvastatin-based Torvacard cov ntsiav tshuaj roj. Ib yam li txhua yam tshuaj nrog cov tshuaj nquag no, cov lus qhia rau kev siv yog qhov muaj txiaj ntsig loj, uas qhia tau tias xav tau kev xyuam xim thiab kev siv tshuaj Torvacard. Cov kev mob tshwm sim feem ntau - hyperglycemia, dyspepsia, flatulence, ntuav, cem quav, belching, daim siab mob siab, mob taub hau, kev fab tshuaj - yog feem ntau ntawm cov tshuaj statin.

Rosuvastatin

Cov ntsiav tshuaj uas muaj tib lub zog sib luag yog cov ntsiav tshuaj liab hauv cov duab sib npaug. Tus txheej txheem ntawm kev ua ntawm rosuvastatin zoo ib yam li cov chaw muag tshuaj ntawm txhua tus statins, cov khoom muaj yog raws li lub subtype ntawm kev sib tw, xaiv cov tshuaj tiv thaiv ntawm HMG-CoA reductase. Lawv tau muab rau:

• nrog thawj, sib xyaw thiab kab mob hypercholesterolemia,
• hypertriglyceridemia,
• kom txo qis roj hauv atherosclerosis thiaj li yuav inhibit nws qhov kev kawm.

Rosuvastatin ua tau zoo ntawm kev tiv thaiv ntawm CVD thiab cov kev mob hnyav rau cov neeg mob uas muaj kev pheej hmoo - mob ntshav siab, tsev neeg txhawb kev mob ntshav siab, mob ntshav siab.

Rosuvastatin Calcium yog ib qho kev ua haujlwm ntawm Roxer ntsiav tshuaj tsim los ntawm Krka. Cov no yog cov tshuaj dawb dawb convex cim “5” ntawm ib sab. Nyob rau hauv kev sib xyaw ua ke ntawm kev tshem tawm, raws li nyob rau hauv cov ntsiav tshuaj saum toj no rau cov roj (cholesterol), nws muaj lactose, raws li cov neeg mob uas muaj mis nyuj tsis muaj suab thaj txaus lossis tsis txaus lactase yuav tsum paub txog.

Tus neeg sawv cev Rosart hypolipidemic yog ua raws li cov qeb roj uas pheej yig nyob rau ntawm rosuvastatin. Nws muaj nyob hauv plaub npaum cov kev xaiv:

• 5 mg - dawb convex round ntsiav tshuaj nrog puag "ST1" ntawm ib sab,
• 10 mg - liab dawb, puag ncig ntsiav tshuaj, cim "ST2",
• 20 mg - tshuaj ntsuab puag ncig, sau npe "ST3",
• 40 mg - ntsiav tshuaj muaj lub ntsej muag oval duab thiab kos "ST4".

Krestor ntsiav tshuaj yog tsim los ntawm cov ceg sib txawv ntawm lub tuam txhab British Astra Zeneca thiab yog cov feem ntau kawm statin raws li rosuvastatin. Vim li no, lawv tseem raug suav hais tias yog ib qho zoo tshaj plaws (thiab tsis pheej yig) tshuaj nyob hauv qeb ntawm lipid-txo tshuaj. Cov ntsiav tshuaj thawj yog qhov yooj yim kom paub qhov txawv ntawm cov xim daj zaj duab xis txheej thiab embossed "ZD45225" ntawm ib sab.

Czech-ua statin Rosucard (qhov nquag ua yog twv hauv lub npe) yog muaj nyob hauv peb txoj kev muab tshuaj:

• 10 mg - convex elongated lub teeb liab ntsiav tshuaj hauv lub plhaub polymer,
• 20 mg - zoo ib yam li cov duab zoo li yav dhau los, tab sis txawv hauv cov xim ntawm lub plhaub, ntawm no nws yog xim paj yeeb,
• 40 mg yog cov ntsiav tshuaj tsaus tsaus.

Rosucard tseem hais txog cov ntsiav tshuaj kim, txawm hais tias daim ntawv teev kev phiv tshuaj thiab kev ceev faj rau lawv siv tsis luv dua li ntawm lwm cov statins. Yog tias koj noj cov tshuaj no raws li qhia thiab kev saib xyuas ntawm tus kws kho mob, kev pheej hmoo ntawm kev cuam tshuam yog tsawg heev.

Lwm cov tshuaj tiv thaiv ntshav siab

Yog tias, tom qab ntsib nrog statins, txoj kev xav kom kho lawv nrog lawv tau ploj zuj zus (thiab ntau tus neeg mob yeej ntshai noj lawv), nws tsim nyog them rau lwm cov tshuaj uas txo cov roj (cholesterol). Cov no yog cov tshuaj ntawm cov pab pawg neeg fibrate - derivatives ntawm fibroic acid, uas txhim kho lipolysis thiab tshem tawm qhov thiaj li hu ua atherogenic lipoproteins (LDL thiab VLDL) los ntawm cov ntshav, nrog rau txo qis cov ntsiab lus ntawm triglycerides. Cov tshuaj no rau cov roj (cholesterol) tsis pheej yig, tab sis koj tuaj yeem khaws cov analogues ntawm Turkish ntau lawm (piv txwv li Lipofen), uas yog 2 zaug pheej yig dua li Fabkis cov tshuaj.

Ntxiv nrog rau cov tshuaj fibrates thiab statins, kev kho lipid-txo qis siv cov tshuaj tiv thaiv kab mob hauv lub cev siv cov tshuaj tiv thaiv kab mob chua ntshav nrog cov nquag tshuaj ezetimibe (Ezetrol), uas tau xaiv inhibit (thaiv) kev nqus ntawm cov khoom cog ntoo thiab sterols hauv plab hnyuv.

Qhov twg zoo dua rau haus?

Dab tsi yuav xaiv los ntawm daim ntawv teev cov tshuaj tsis sib xws, cov tshuaj twg yog qhov zoo dua rau haus? Statins thiab fibrates kev ntshai nrog lawv cov teebmeem ntawm daim siab thiab lub cev nqaij pob txha, cov tshuaj tshiab kawg kim heev. Cov kws kho mob pom zoo tias koj txawm li cas los xij pib ua tib zoo saib xyuas thiab tswj kom muaj statins thiab, yog tias nws hloov tawm tias lawv muaj txiaj ntsig zoo thiab muaj kev tiv thaiv zoo, koj tuaj yeem yauv tau txais kev kho mob tag nrho.

Yog tias statins lossis fibrates tsis haum, muaj lwm cov ntsiav tshuaj los ntawm cov pab pawg ntawm cov cholesterol los tiv thaiv kev nqus lossis tshuaj ua kom sib xyaw raws lawv.

Qee lub sij hawm koj tuaj yeem hnov ​​tau tias lub cev pabcuam ntxiv (BAA) Zog tuaj yeem siv ua cov ntsiav tshuaj roj. Tab sis raws li cov lus qhia rau kev siv, cov khoom lag luam nrog cov lag luam npe hu ua Energia yog cov vitamins thiab cov zaub mov muaj txiaj ntsig rau cov neeg tsis txaus siab ntawm qee yam kab kawm thiab vitamins. Qhov tseeb hais tias Lub Zog yog cov ntsiav tshuaj roj nws tsis hais hauv qhov tseem ceeb. Cov tshuaj feem ntau tsis yog tshuaj kho mob, tsis hais txog lub zog ntawm metabolism, yog li ntawd, nws tsis pom zoo kom muab nws ua lub luag haujlwm ntawm lipid-txo qis tus neeg sawv cev.

Cov neeg mob yog yam yuav tsis meej pem Lub Zog nrog kev sib xyaw lipid-txo tus neeg sawv cev ntawm Italian lossis Singapore-ua Imeji raws li simvastatin thiab ezetimibe (statin thiab cholesterol nqus inhibitor). Qhov no nws yog qhov zoo tiag tiag kho rau hypercholesterolemia.

Nws yog qhov yuav tsum tau hais txog Alisat ntsiav tshuaj (los yog "Qej"), uas ntau tus xav tias yog cov ntsiav tshuaj roj (cholesterol). Kev noj zaub mov kom zoo yog npaj rau lub cev ua kom tsis muaj zog ntawm allicin, ib qho tshuaj organic nrog cov tshuaj tua kab mob thiab bactericidal thaj chaw.

Yog tias koj xav tau kev kho kom zoo tsis yog nrog tshuaj noj rau cov cholesterol, tab sis nrog kev noj zaub mov muaj txiaj ntsig, koj tuaj yeem them sai sai rau Aterolex tsiav tshuaj, uas pab txhim kho lipid metabolism, tswj lawv kev siv nrog kws kho mob.

Cov twg yog qhov pheej yig?

Yog tias koj xaiv cov tshuaj kom txo cov roj hauv cov ntshav los ntawm qeb pheej yig, tom qab ntawd koj yuav tsum nrhiav rau lawv ntawm cov tshuaj ntawm cov pab pawg statin:

• Atorvastatin (nrog tib yam tshuaj muaj yees),
• Cardiostatin (lovastatin),
• Reddistatin (rosuvastatin),
• Vasilip (simvastatin).

Niaj hnub no, cov no yog cov tshuaj pheej yig tshaj plaws rau ntshav siab.

Muaj tsawg kawg ntawm kev phiv

Lub hom phiaj tseem ceeb ntawm cov tshuaj tshiab yog los txo cov kev mob tshwm sim thaum tswj kev ua haujlwm siab ntawm cov tshuaj. Yog li, cov ntsiav tshuaj los ntawm cov roj ntsha tshiab nyob rau hauv cov ntshav - tshuaj tiv thaiv cov roj uas txhaws hauv cov hnyuv (Ezetrol) - yog suav tias yog cov tshuaj lipid-txo cov tshuaj zoo. Qhov no tsis yog hais tias cov tshuaj no tsis muaj kev mob tshwm sim - lawv yog thiab lawv cov npe muaj ntau heev. Tab sis raws li cov lus qhia rau kev siv, cov yeeb yam tsis txaus siab no tau pom nyob hauv pawg "tsis tshua muaj" thiab "tsis tshua muaj", uas hais txog kev nyab xeeb.

Puas yog yuav ua tau kom txo qis thiab nrawm?

Nws yog qhov nyuaj rau ib tus neeg uas tsis siv los mloog cov xwm txheej kom pom zoo tias yuav tsum tau noj tshuaj ntev thiab ua raws kev noj haus. Cov neeg mob no ua siab luv thiab tab tom nrhiav rau cov tshuaj uas txo cov roj cholesterol sai thiab zoo. Thiab nws muaj peev xwm tsis tuaj yeem yog cov ntsiav tshuaj, vim tias qhov kev txum tim rov qab los ntawm cov rog metabolism tsim nyog kom tswj cov qib roj hauv cov ntshav yog cov txheej txheem ntev, thiab maj mam tiav. Nws yog tsis tuaj yeem kho tus kab mob nrog ob peb ntsiav tshuaj, uas qee zaum tsim xyoo dhau los. Yog li, cov neeg mob hypercholesterolemia yuav tsum npaj rau kev kho lub sijhawm ntev thiab cov kev hloov pauv loj hauv kev ua neej.

Saib Xyuas Ib Zuag Lus

Kev soj ntsuam cov neeg mob ntawm cov tshuaj sib txawv ntawm lipid-txo cov tshuaj yog qhov txaus siab, cia koj nkag siab tias qhov twg ntawm lawv zoo dua, uas ua tau zoo dua.

Raws li kev ntsuam xyuas tus neeg mob, feem ntau ntawm lawv raug kho nrog cov statins uas tau muab rau lawv hauv chaw kho mob. Los ntawm pawg tshuaj no, atorvastatin thiab rosuvastatin raws li cov ntsiav tshuaj roj (cholesterol) tau txais kev tshuaj xyuas zoo. Los ntawm txoj kev, rosuvastatin hu ua qhov zoo tshaj plaws, vim tias thaum lub sijhawm tswj hwm feem ntau cov neeg mob tsis muaj kev phiv tshuaj dab tsi.

Ntawm cov fibrates, Tricor tau txais kev tshuaj xyuas zoo.

Ezetrol yog hu ua cov ntsiav tshuaj roj zoo tshaj plaws, tab sis ob tus kws kho mob thiab cov neeg mob nco tias nws yog "yam tshuaj tsis muaj nqi."

Yuav ua li cas txo cov roj cholesterol tsis muaj tshuaj?

Qhia txog cov kev pheej hmoo thiab nyiaj txiag ntawm kev kho mob, ntau tus neeg mob nrhiav nrhiav lwm yam tshuaj tsis zoo rau kev kho lipid-txo qis. Thiab cov hau kev no muaj nyob, txawm hais tias lawv xav tau kev mob siab tshwj xeeb, kev qhuab qhia thiab ua siab ntev, vim tias cov hau kev no yuav tsis tau muab cov txiaj ntsig sai. Nws yog ib nqe lus nug ntawm kev tshem tawm cov teeb meem no tshwm sim ntawm lipid metabolism cuam tshuam vim kev tawm dag zog lub cev, kev coj tsis zoo thiab kev noj zaub mov tsis zoo.

Cov txheej txheem ntawm cov tshuaj tsis yog tshuaj yuav tsum muaj lub koom haum ntawm kev coj ua hnub nrog kev so kom txaus thiab txo kev ntxhov siab.

Txhawm rau tshem tawm cov zaub mov ntawm cov khoom tsis zoo, koj tuaj yeem tso koj lub plab zom mov los ntawm qhov yuav tsum tau nqus cov rog thiab saccharides ntau heev, uas yuav muaj feem cuam tshuam rau lipid profile. Thiab txhawm rau tswj cov qib roj cholesterol hauv cov ntshav, nws yog ib qho tsim nyog yuav tau soj ntsuam cov zaub mov lipid-txo qis tshwj xeeb uas pab cov metabolism hauv lub cev.

Kev ua neej nquag

Kev siv lub cev tsis txaus ua rau cov ntshav tsis sib haum thiab kev tso tawm (tshem tawm) ntawm lub zog tsis muaj tseeb cov roj ntsha hauv lub cev. Lawv muab tso rau hauv yuav luag txhua qhov tseem ceeb hauv nruab nrog, cuam tshuam nrog lawv cov kev coj ua haujlwm tsis zoo thiab cuam tshuam cov roj metabolism hauv lub cev. Hloov lub neej ntawm kev ua kom lub cev muaj zog pab txhim kho cov ntshav ncig thiab ua kom txhua tus txheej txheem, nrog rau cov rog metabolism. Vim li ntawd nws thiaj li tseem ceeb uas yuav tau koom kev tawm dag zog - kev tawm dag zog txhua hnub thaum sawv ntxov, khiav, taug kev, ua luam dej ob peb zaug hauv ib lub lim tiam, ua haujlwm kom niaj hnub ua haujlwm (tshwj xeeb yog tias nws yog sedentary).

Kev ntxuav cov hlab nrog qhov kev kho mob pej xeem

Cov tshuaj hauv pej xeem kuj pom qhov chaw nyob rau hauv kev kho lipid-txo qis. Xwm muaj ntau nyob rau hauv cov nroj tsuag uas pab txhawb kev txhim kho ntawm cov metabolism hauv kev thiab ua kom muaj cov rog. Cov yam ntxwv no yog lub hauv paus ntawm cov zaub mov noj rau cov tshuaj ua ntshav ua kom ntshav thiab cov roj tsawg. Thaum pib kho nrog tshuaj ntsuab tshuaj, nws yuav tsum nco ntsoov tias kev kho tshuaj ntsuab yog ib qho txheej txheem ntev, thiab lawv kuj tuaj yeem muaj kev phiv tshuaj thiab sib kis.