Yuav ua li cas siv tshuaj yeeb Gluconorm Plus?

- uas ketoacidosis, mob ntshav qab zib precoma, mob ntshav qab zib coma,

- Lub raum khiav tsis zoo,

- mob hnyav uas tuaj yeem ua rau lub raum hloov pauv (lub cev qhuav dej, ua mob hnyav, ua rau poob siab),

- mob ceev los yog mob ntev nrog cov nqaij mos hypoxia (mob plawv lossis ua pa tsis ua haujlwm, tsis ntev los no myocardial infarction, poob siab),

- cov kab mob kis, kev cuam tshuam loj ntawm kev phais mob, kev raug mob, kev kub nyhiab thiab lwm yam mob uas yuav tsum muaj tshuaj tua kab mob,

- ntev kev haus cawv, qaug cawv kom qaug,

- lactic acidosis (suav nrog keeb kwm),

- siv tsawg kawg 48 teev ua ntej thiab nyob rau hauv 48 teev tom qab ua kev tshawb fawb radioisotope lossis X-ray nrog kev qhia ntawm iodine-contrast contrast medium,

- kev ua raws li kev noj zaub mov kom tsis txhob muaj calories ntau tsawg (tsawg dua 1000 calories / hnub),

- lub sijhawm pub niam mis,

- Ua haujlwm kom muaj qhov cuam tshuam rau metformin, glibenclamide lossis lwm yam sulfonylurea derivatives, thiab ntxiv rau cov tshuaj pab tsis haum.

Yuav siv li cas: noj ntau thiab hom tshuaj kho

Sab hauv, thaum noj mov.

Feem ntau cov tshuaj pib yog 1 tab. (400 mg / 2.5 mg) / hnub. Txhua 1-2 lub lis piam tom qab pib kho, qhov tshuaj ntawm cov tshuaj tau kho raws li qib ntshav cov ntshav nyob hauv lub cev. Thaum hloov cov kev sib txuas ua ke dhau los nrog metformin thiab glybeklamide, 1-2 ntsiav tshuaj yog kws kho. Gluconorm nyob ntawm seb koob tshuaj dhau los ntawm txhua qhov.

Qhov siab tshaj plaws niaj hnub noj yog 5 ntsiav tshuaj.

Pharmacological kev txiav txim

Glibenclamide stimulates insulin secretion los ntawm qhov qis dua qhov pib ntawm cov piam thaj-cell pancreatic voos, nce insulin rhiab heev thiab qhov ntau ntawm nws khi rau cov phiaj hlwb.

Metformin txo cov ntshav qabzib ntau ntau los ntawm kev nkag siab ntawm cov ntaub so ntswg txuas ntxiv mus rau insulin thiab txhim kho cov piam thaj ntxiv.

Sab sij huam

Ntawm ib feem ntawm cov khoom noj metabolism carbohydrate: hypoglycemia yog ua tau.

Los ntawm lub plab zom mov thiab daim siab: tsis tshua muaj - xeev siab, ntuav, mob plab, poob qab los noj mov, "nws yog xim hlau" saj hauv lub qhov ncauj, qee qhov - cholestatic jaundice, nce kev ua haujlwm ntawm daim siab enzymes, kab mob siab.

Los ntawm cov kab mob hemopoietic: tsis tshua muaj - leukopenia, thrombocytopenia, erythrocytopenia, tsis tshua muaj tshwm sim - agranulocytosis, hemolytic lossis megaloblastic anemia, pancytopenia.

Kev ua xua thiab immunopathological: tsis tshua muaj - urticaria, erythema, tawv nqaij khaus, kub ib ce, mob pob txaws, mob ntshav qab zib.

Dermatological tshua: tsis tshua muaj - photosensitivity.

Los ntawm sab ntawm cov metabolism: lactic acidosis.

Cov lus qhia tshwj xeeb

Kev phais mob thiab kev raug mob loj, kev kub nyhiab, kev kis mob nrog febrile syndrome yuav tsum tsis siv tshuaj ntxiv thiab teem caij rau tshuaj insulin.

Nws yog ib qho tsim nyog yuav tau soj ntsuam cov qib ntawm cov piam thaj hauv cov ntshav ntawm lub plab khoob thiab tom qab noj mov.

Cov neeg mob yuav tsum ceeb toom qhia txog kev pheej hmoo yuav muaj ntshav qab zib tsawg nyob rau hauv muaj ethanol, NSAIDs, thiab tshaib plab.

Kev sib txuam

Ethanol tsub kom muaj feem ntau ntawm cov kab mob lactic acidosis.

Barbiturates, corticosteroids, adrenostimulants (epinephrine, clonidine), cov tshuaj tiv thaiv kab mob (phenytoin), qeeb calcium calcium blockers, carbonic anhydrase inhibitors (acetazolamide), thiazide diuretics, chlortalidone, furosemide, diazanazide, triazene diazenterine , morphine, ritodrine, salbutamol, terbutaline, glucagon, rifampicin, iodine-muaj cov thyroid hormones, lithium ntsev, hauv kev txhaj tshuaj ntau - nicotinic acid, chlorpromazine, tshuaj tiv thaiv qhov ncauj thiab estrogens.

ACE inhibitors (captopril, enalapril), histamine H2 receptor blockers (cimetidine), cov tshuaj tua kab mob (miconazole, fluconazole), NSAIDs (phenylbutazone, azapropazone, oxyphenbutazone), fibrates, tshuaj tua kab mob (clobate) , salicitates, coumarin anticoagulants, anabolic steroids, beta-blockers, MAO inhibitors, ntev sulfonamides, cyclophosphamide, chloramphenicol, phenfluramine, fluoxetine, guanethidine, pentoxifylline, tetracycline, theophylline, tubular secretion blockers, reserpine, bromocriptine, disopyramide, pyridoxine, lwm yam tshuaj hypoglycemic (acarbose, biguanides, insulin), allopurinol.

Cov lus nug, cov lus teb, tshuaj xyuas ntawm cov tshuaj Gluconorm Plus

Cov ntaub ntawv muab yog npaj rau kev kho mob thiab kws tshaj lij. Cov ntaub ntawv muaj tseeb tshaj plaws txog cov tshuaj muaj nyob hauv cov lus qhia uas txuas nrog lub ntim los ntawm cov kws tsim khoom lag luam. Tsis muaj cov ntaub ntawv tso tawm rau ntawm no lossis lwm nplooj ntawv ntawm peb lub xaib tuaj yeem hloov chaw rau qhov tsis txaus siab tus kheej rau tus kws tshaj lij.

Tso cov ntaub ntawv thiab cov nyob ua ke

Cov tshuaj muaj tsuas yog hauv cov qauv hauv cov ntsiav tshuaj. Muaj cov khoom xyaw uas nquag: glibenclamide thiab metformin hydrochloride. Tsuas tshuaj nyob rau hauv 1 ntsiav tshuaj, ntsig txog: 2.5 thiab 5 mg, 500 mg. Ntxiv rau qhov sib xyaw ua ke ntawm cov tshuaj yeeb yaj kiab, cov lus qhia kuj tseem suav nrog cov qauv txheej txheem rau cov ntawv tso tawm no:

• microcrystalline cellulose,
• Kev Hyprolose
• croscarmellose sodium
• magnesium stearate.

Cov ntsiav tshuaj yog coated nrog ib txheej tshwj xeeb uas txo tus nqi ntawm kev tso tawm ntawm cov tshuaj yeeb dej caw. Vim tias qhov no, qib ntawm kev ua phem rau ntawm cov qog ua kua ntawm lub plab tau txo qis. Koj tuaj yeem yuav cov khoom hauv cov pob nrog 30 ntsiav tshuaj.

Cov tshuaj muaj tsuas yog hauv cov qauv hauv cov ntsiav tshuaj. Muaj cov khoom xyaw uas nquag: glibenclamide thiab metformin hydrochloride.

Cov Tshuaj Pharmacokinetics

Metformin yuav nrawm heev. Cov theem ntawm nws cov kev xav hauv cov ntshav cov ntshav nce mus rau tus nqi tsis pub dhau tom qab 2 teev. Qhov tsis zoo ntawm qhov khoom yog xim luv. Tom qab 6 teev, kev txo ntshav plasma concentration ntawm metformin pib, uas yog vim qhov kawg ntawm txoj kev nqus hauv cov zom zaub mov. Lub sijhawm ib nrab ntawm lub cuab yeej tseem txo qis. Lub sijhawm nws txawv ntawm 1.5 txog 5 teev.

Ib qho ntxiv, metformin tsis khi rau cov nqaijrog plasma. Qhov tshuaj yeeb dej caw no muaj peev xwm sib txuam hauv cov nqaij hauv ob lub raum, mob siab, mob qog. Lub raum ua haujlwm tsis zoo yog qhov tseem ceeb uas ua rau kom muaj kev txuam nrog metformin hauv lub cev, uas ua rau muaj qhov nce ntawm cov tshuaj no thiab ua rau nws cov hauj lwm zoo.

Lub raum ua haujlwm tsis zoo yog qhov tseem ceeb uas ua rau kom muaj kev txuam nrog metformin hauv lub cev, uas ua rau muaj qhov nce ntawm nws cov hauj lwm zoo.

Glibenclamide siv sijhawm ntev dua - rau 8-12 teev. Lub siab ntawm kev ua haujlwm tshwm sim hauv 1-2 teev. Qhov tshuaj no tau khi rau cov ntshav protein. Cov txheej txheem ntawm kev hloov pauv ntawm glibenclamide tshwm sim hauv daim siab, qhov twg 2 lub tebchaw tsim tau uas tsis muaj kev cuam tshuam hypoglycemic.

Kev ntsuas rau siv

Cov tshuaj tau tso cai los siv hauv kev kho mob ntawm cov neeg mob ntshav qab zib hom 2 hauv qee kis:

• tsis muaj qhov tshwm sim nrog kev kho yav dhau los ua rau kev rog, yog tias ib qho ntawm cov tshuaj: Metformin lossis Glibenclamide tau siv,
• ua cov kev hloov pauv hloov, muab tau hais tias theem ntawm cov piam thaj hauv cov ntshav yog ruaj khov thiab tswj tau zoo.

Daim ntawv tso tawm

Gluconorm yog tsim nyob rau hauv daim ntawv ntawm round ntsiav tshuaj ntawm dawb ntxoov ntxoo nrog ib txheej coated. 10 thiab 20 daim nyob hauv ib lub hlwv, 2 lossis 4 hlwv ib pob ntawv thawv.

Tus nqi ntawm gluconorm nyob ntawm 220 txog 390 rubles, raws li cov naj npawb ntawm cov ntsiav tshuaj hauv daim npav pob.

Cov tshuaj muaj ob qho tshuaj tseem ceeb - glibenclamide (2.5 mg) thiab metformin hydrochloride (0.4 g).

Cov khoom siv ntxiv: microcrystalline cellulose, pob kws hmoov txhuv nplej siab, colloidal silicon dioxide, huv si talc, diethyl phthalate, gelatin, cellulose acetate phthalate, sodium carboxymethyl starch, croscamellose sodium.

Cov lus qhia rau kev siv

Gluconorm ntsiav tshuaj noj ntawm qhov ncauj thaum noj. Cov koob tshuaj tau txiav txim siab ib tus zuj zus, raws li theem ntawm cov piam thaj hauv cov ntshav ntawm tus neeg mob. Tus qauv muab tshuaj thaum pib kho yog 1 ntsiav tshuaj ib hnub. Tom qab 2 lub lis piam, nws yog ib qho tsim nyog yuav tau hloov kho qhov koob tshuaj nyob ntawm seb muaj nuj nqis ntawm kev kuaj ntshav.

Cov lus qhia rau kev siv ntawm Gluconorm qhia tau hais tias nrog kev hloov kho nws yuav tsum tau noj 1-2 ntsiav tshuaj, noj mus rau hauv tus lej ua ntej ntau ntawm cov khoom tseem ceeb. Qhov siab tshaj plaws rau ib hnub twg nce txog 5 ntsiav tshuaj.

Cov ntsiav tshuaj hypoglycemic yog daim ntawv yuav tshuaj. Lawv yuav tsum muab cia rau qhov kub txog 25 degrees nyob rau hauv cov ntaub ntawv pov thawj menyuam yaus, tiv tshav ntuj ncaj qha. Lub txee lub neej ntawm cov khoom yog 36 lub hlis txij li hnub ntawm kev tsim khoom.

Daim ntawv thov nta

Nws yog ib qho tsim nyog yuav tsum tshem tawm kev kho mob nrog rau cov tshuaj rau kis kab mob nrog kev kub taub hau, nrog kev raug mob loj thiab kev cuam tshuam kev phais. Txoj kev pheej hmoo ntawm kev txo qis cov ntshav qab zib thaum lub sij hawm tshaib plab, kev siv cov NSAIDs, ethanol yog nce ntxiv. Dosage kev kho kom haum yog nqa tawm thaum hloov pauv kev noj haus, ua kom lub cev muaj zog thiab lub dag lub zog dhau los.

Kev tsim kho hauv ntshav qab zib - tsuas yog haus txhua txhua hnub.

Cov lus qhia Gluconorm piav qhia tias nws tsis pom zoo kom haus dej cawv thaum kho. Cov tshuaj ntsiav tuaj yeem cuam tshuam qhov ceev ntawm psychomotor kev ua haujlwm thiab txo qis. Yog li, koj yuav tsum ceev faj thaum tsav tsheb tsim kev phom sij thiab tsheb.

Nws yog txwv tsis pub noj tshuaj thaum yau, thaum cev xeeb tub, thaum pub niam mis, vim tias lub hauv paus tseem ceeb nkag mus rau niam lub mis. Cov tshuaj yog contraindicated nyob rau hauv cov neeg nrog pathologies ntawm ob lub raum thiab mob siab. Kev siv cov ntsiav tshuaj hauv cov neeg laus yog tsis pom zoo nrog kev ua kom lub cev hnyav.

Noj ntau dhau

Kev siv tshuaj rau tus kheej thiab tshaj qhov tsis pub noj tshuaj yog qhov ua rau ntau tshaj ntawm cov tshuaj. Tus mob no ua rau cov tsos mob ntawm cov kab mob lactic acidosis vim yog metformin, uas yog ib feem ntawm cov tshuaj. Tus neeg mob sau tseg qhov tshwm sim ntawm xeev siab, ntuav, tsis muaj zog, mob leeg. Nrog rau cov tsos mob thawj zaug ntawm kev noj ntau dhau, kev kho mob raug tso tseg. Nrog cov kab mob lactic acidosis, txoj kev kho yog nqa tawm hauv ib lub tsev kho mob. Qhov kev kho mob uas zoo tshaj plaws yog hemodialysis.

Peb muab cov luv nqi rau cov nyeem ntawm peb lub xaib!

Qhov muaj pes tsawg leeg muaj cov tshuaj glibenclamide, qhov kev xav zoo ntawm uas ua rau kev txhim kho hypoglycemia. Cov tsos mob tseem ceeb ntawm tus mob no:

• mob taub hau
• kiv taub hau
• nce qab los noj mov
• feem ntau tsis muaj zog
• pallor ntawm cov epidermis,
• kev xav txawv
• cov leeg hlwb,
• arrhythmia,
• tsaug zog
• teeb meem kev sib koom tes
• npau suav phem
• paresthesia ntawm lub qhov ncauj mucosa.

Nrog exacerbation ntawm hypoglycemia, muaj kev tsis zoo hauv tus neeg mob li, ploj ntawm kev tswj thiab nco qab yog cai. Nrog lub teeb thiab mob hnyav tiv thaiv kab mob, cov kua nplaum nyob tshuaj. Hauv cov xwm txheej ntau dua, thaum muaj qhov tsis nco qab, qhov 40% piam thaj ua rau cov piam thaj lossis glucagon siv. Txhawm rau zam dhau qhov tshwm sim txuas ntxiv ntawm kev txo ntshav siab, tus neeg mob yuav tsum noj zaub mov ntau ntxiv nrog cov carbohydrates tom qab ua kom lub cev rov qab zoo li qub.

Cov tshuaj yuav tuaj yeem hloov cov tshuaj xws li Bagomet Plus thiab Glukovans. Cov khoom lag luam no muaj qhov sib txuam zoo sib xws nrog Gluconorm. Cov ntsiav tshuaj xws li Glucofage thiab Glybomet yog cov analogues ntawm Gluconorm uas muaj metformin. Nws raug txwv tsis pub siv lwm yam tshuaj yam tsis muaj kws kho mob sau ntawv txhawm rau kom tsis txhob muaj kev phom sij thiab ua rau tus neeg mob mob.

Cov ntsiav tshuaj pab qee tus neeg mob, thaum lwm tus ua rau muaj kev phiv. Hauv qab no yog qee qhov kev tshuaj xyuas txog tus mob ntshav qab zib Gluconorm.

Kuv tau kuaj mob ntshav qab zib 7 xyoo dhau los. Tus kws kho mob tau sau ntawv tawm Gluconorm ua ib txoj kev kho mob. Kuv haus ib ntsiav tshuaj ib hnub, ntxuav nrog dej. Kuv xis nyob. Kuv txoj kev kho mob suav nrog kev noj tshuaj, kev yoo mov. Txog tam sim no, tsis pom qhov tsis zoo tshwm sim.

Nrog rau ntshav qab zib, Kuv tau raug hais kom haus ntshav qab zib Gluconorm txhua hnub thaum sawv ntxov thiab yav tsaus ntuj. Cov piam thaj nyob rau hauv cov hlab ntshav rov qab mus rau qhov qub, tab sis qhov mob taub hau txaus thiab lub plab zom mov tau tshwm sim. Raws li nws muab tawm, Kuv muaj contraindications rau cov tshuaj no. Kuv yuav tsum tau hloov cov tshuaj.

Mob ntshav qab zib ib txwm ua rau neeg tuag taus. Muaj ntshav qab zib ntau dhau yog qhov txaus ntshai heev.

Aronova S.M. muab cov lus qhia txog kev kho mob ntshav qab zib. Nyeem tag nrho

Pharmacological pawg

Qhov muaj pes tsawg leeg ntawm Gluconorm suav nrog ob qho kev sib xyaw, uas ua ke muab cov nyhuv hypoglycemic.

Metformin belongs rau cov pab pawg ntawm biguanides, uas ua rau muaj qhov tsis kam ntawm cov hlwb rau insulin, uas ua rau muaj kev siv nrawm nrawm rau cov piam thaj. Qhov tshuaj no cuam tshuam cov txheej txheem metabolic hauv lub siab, tswj kev tshuav nyiaj hauv kev tsim cov cholesterol thiab triglycerol. Kev nqus ntawm cov carbohydrates los ntawm cov hnyuv txo yog tsawg.

Glibenclamide yog sulfonylurea derivative. Nrog nws cov kev pab, insulin secretion yog nqa tawm, uas ua tiav los ntawm kev kis tau ntawm cov kab mob hlwb pancreatic. Muab cov kev xav tob tob ntawm lub cev lub cev rau insulin, inhibiting lipolysis ntawm cov ntaub so ntswg adipose.

Tsuas tshuaj thiab tswj hwm

Kev siv ntau tshaj ntawm cov tshuaj yog txiav txim los ntawm tus kws kho mob, raws li qhov ntsuas ntawm cov ntshav qab zib. Kev kho yuav pib nrog qhov tsawg kawg ntawm cov tshuaj, uas yog ib nrab ntawm ib ntsiav tshuaj ib hnub ib zaug.

Txhawm rau kom tsis txhob muaj kev txhim kho hypoglycemia, nws pom zoo kom noj 1 ntsiav tshuaj ntawm cov tshuaj 1 zaug hauv ib hnub nrog zaub mov. Qhov no ua tau zoo tshaj plaws thaum sawv ntxov, vim tias maj mam ua ntawm cov khoom noj hauv lub cev tom qab noj su.

Thaum tsis muaj kev ua tau zoo, qhov muab tshuaj yog maj maj. Qhov siab tshaj plaws txhua hnub siv yuav tsum tsis pub tshaj 5-6 ntsiav tshuaj. Yog tias nws yuav tsum tau siv cov koob tshuaj ntau dua li kev pom zoo, tus neeg mob yuav tsum tau saib xyuas tas li los ntawm cov kws tshwj xeeb.

Gluconorm ntxiv rau

Kev nce siab ntxiv ntawm Glibenclamide tso cai rau koj siv tsuas yog 1 ntsiav tshuaj hauv ib hnub kom tau txais cov nyhuv hypoglycemic ruaj khov. Hom tshuaj twg haum rau hauv qee kis, tus kws kho mob yuav qhia.

Ua gluconorm ntxiv rau cov ntsiav tshuaj zoo li cas?

Feem ntau, kev kho mob pib nrog Gluconorm li ib txwm, thaum tsis muaj kev ua haujlwm ntawm lawv hloov mus rau daim ntawv txhim kho nrog cov ntsiab lus siab ntawm Glibenclamide.

Yeeb tshuaj sib cuam tshuam

Kev siv ib txhij ntawm cov tshuaj Gluconorm ntxiv thiab Miconazole, nrog rau lwm cov tshuaj antimycotic, uas, thaum sib cuam tshuam, provokes kev loj hlob ntawm tus mob ntshav qab zib tsis xeev, txawm tuag taus, yog nruj me ntsis txwv tsis pub.

Tsis txhob coj gluconorm nrog cawv

Koj tsis tuaj yeem siv tus neeg sawv cev hypoglycemic nrog rau cawv, uas provokes pathological txo qis rau hauv cov ntshav siab thiab lub plawv dhia.

Nrog rau kev ceev faj, cov tshuaj no ua ke nrog glucocorticosteroids thiab tshuaj, uas suav nrog iodine.

Cov yam ntxwv ntawm kev siv

Gluconorm tsis pom zoo rau cov neeg mob tom qab 65 xyoo, vim muaj kev pheej hmoo ntawm kev tsim cov nyom, suav nrog kev txhim kho mob ntshav qab zib tsis xeev. Tom qab 45 xyoo, kev kho mob pib nrog kev txhaj tshuaj tsawg kawg, thiab yog tias tsim nyog, lawv nce ntxiv yuav tsum muaj kev soj ntsuam tas li ntawm tus neeg mob tus mob.

Thaum cev xeeb tub, kev siv cov tshuaj no yog nruj me ntsis txwv tsis pub, txij li cov feem ua haujlwm pab txhawb kev ua txhaum ntawm kev txhim kho tag nrho ntawm tus me nyuam hauv plab.Qhov no nyeg nce cov kev pheej hmoo ntawm kab mob plab yug me nyuam, nrog rau kev nchuav menyuam thaum ntxov.

Cov tshuaj hauv qab no zoo sib xws thiab muaj pes tsawg leeg:

Kev xaiv ntawm ib lossis lwm qhov cuab yeej uas tuaj yeem txo cov ntshav qab zib nyob ntawm nws qib ntawm cov ntshav qab zib thiab cov kab mob ntsig txog. Tsuas yog tus kws kho mob muaj txoj cai kom muab tshuaj, xaiv cov tshuaj zoo tshaj plaws hauv qee kis. Kev noj tshuaj rau tus kheej yog qhov txaus ntshai rau kev txhim kho mob ntshav qab zib tsis xeev plab thiab lwm yam tsis zoo hauv lub neej.