Flemoklav Solutab 875 125 mg - cov lus qhia rau kev siv

Flemoklav Solutab 875 + 125 mg - ib cov tshuaj los ntawm pab pawg ntawm penicillins nrog qhov kev pom ntawm qhov dav dav. Kev npaj ua ke ntawm amoxicillin thiab clavulanic acid, beta-lactamase inhibitor.

Muaj ib ntsiav tshuaj:

Kev ua kom nquag plias: amoxicillin trihydrate (uas sib haum rau amoxicillin lub hauv paus) - 1019,8 mg (875.0 mg), potassium clavulanate (uas sib haum rau clavulanic acid) - 148.9 mg (125 mg).
Cov neeg siv: tawg cellulose - 30.4 mg, microcrystalline cellulose - 125.9 mg, crospovidone - 64.0 mg, vanillin - 1.0 mg, tangerine tsw - 9.0 mg, txiv qaub tsw - 11.0 mg, saccharin - 13.0 mg; magnesium stearate - 6.0 mg.

Kev xa Khoom

Kwv yees li 25% ntawm clavulanic acid thiab 18% ntawm plasma amoxicillin cuam tshuam nrog cov protein plasma. Qhov ntim ntawm kev faib tawm ntawm amoxicillin yog 0.3 - 0.4 l / kg thiab qhov ntim ntawm kev faib clavulanic acid yog 0.2 l / kg.

Tom qab kev tswj hwm kev mob ntshav, amoxicillin thiab clavulanic acid tau pom nyob hauv lub zais zis, lub plab hauv plab, tawv nqaij, rog thiab cov leeg nqaij, hauv cov kua nqaij synovial thiab peritoneal, nrog rau hauv cov kua tsib. Amoxicillin pom nyob rau niam mis.

Amoxicillin thiab clavulanic acid hla qhov chaw tiv thaiv hniav.

Biotransformation

Amoxicillin yog qee tawm ua ke nrog tso zis hauv kev tsis ua haujlwm ntawm penicilloid acid, nyob rau hauv tus nqi ntawm 10-25% ntawm thawj koob tshuaj. Clavulanic acid yog metabolized hauv daim siab thiab lub raum (tso tawm hauv cov zis thiab cov quav), nrog rau cov pa roj carbon dioxide nrog cov pa tawm.

Ib nrab-lub neej ntawm amoxicillin thiab clavulanic acid los ntawm cov ntshav cov ntshav hauv cov neeg mob uas lub cev tsis zoo ua haujlwm yog kwv yees li 1 teev (0.9-1.2 teev), hauv cov neeg mob creatinine tshem tawm hauv 10-30 ml / min yog 6 teev, thiab nyob rau hauv cov ntaub ntawv ntawm anuria nws txawv ntawm 10 thiab 15 teev. Cov tshuaj yog tawm thaum lub sij hawm hemodialysis.

Li ntawm 60-70% ntawm amoxicillin thiab 40-65% ntawm clavulanic acid raug tso tawm tsis hloov nrog cov zis nyob rau thawj 6 teev.

Kev ntsuas rau siv

Kev sib xyaw ntawm amoxicillin nrog clavulanic acid yog qhia rau kev kho mob ntawm cov kab mob ntawm cov chaw hauv qab no tshwm sim los ntawm cov kab mob me me nkag siab rau kev sib xyaw ntawm amoxicillin nrog clavulanic acid:

Cov mob ua pa sab saud (suav nrog rau mob ENT), piv txwv li mob ua mob tonsillitis, mob ntsws, mob otitis, feem ntau tshwm sim los ntawm Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis, thiab Streptococcus pyogenes.
Cov kab mob ua pa tsawg dua, xws li exacerbations ntawm mob ntsws ntev, lobar mob ntsws, thiab mob ntsws, feem ntau tshwm sim los ntawm Streptococcus pneumoniae, Haemophilus influenzae, thiab Moraxella catarrhalis.
Kab mob Urogenital, xws li mob cystitis, mob urethritis, pyelonephritis, poj niam mob qhov chaw mos, feem ntau tshwm sim los ntawm hom kab mob Enterobacteriaceae (feem ntau Escherichia coli), Staphylococcus saprophyticus thiab hom kab mob ntawm genus Enterococcus, nrog rau tus kab mob gonorrhea los ntawm Neisseria gonorrhoeae.
Kev kis mob ntawm daim tawv nqaij thiab cov nqaij mos, feem ntau tshwm sim los ntawm Staphylococcus aureus, Streptococcus pyogenes, thiab hom ntawm cov genus Bacteroides.
Kev kis mob ntawm cov pob txha thiab pob qij txha, piv txwv li osteomyelitis, feem ntau tshwm sim los ntawm Staphylococcus aureus, yog tias tsim nyog, kev kho mob ntev yog ua tau.
Cov kab mob Odontogenic, piv txwv li, mob qog nqaij hlav, kab mob hu ua odontogenic maxillary sinusitis, mob hniav ntau heev nrog nthuav tawm cellulitis.
Lwm yam kev sib xyaw ua ke (piv txwv, septic rho menyuam tawm, tom qab sepsis, mob plab hauv plab) ua ib feem ntawm txoj kev kho mob.

Cov kab mob tshwm sim los ntawm cov kab mob me me uas nkag rau amoxicillin tuaj yeem kho nrog Flemoklav Solutab®, vim tias amoxicillin yog ib qho ntawm nws cov khoom xyaw tseem ceeb. Flemoklav Solutab® tseem qhia txog kev kho mob sib kis mob los ntawm cov kab mob me me nkag rau amoxicillin, thiab cov kab mob me me uas tsim cov beta-lactamase, rhiab rau kev sib xyaw ntawm amoxicillin nrog clavulanic acid.

Qhov rhiab ntawm cov kab mob mus rau kev sib xyaw ua ke ntawm amoxicillin nrog clavulanic acid nws txawv nyob ntawm thaj av thiab dhau sijhawm. Qhov tsim nyog, cov ntaub ntawv hais txog qhov chaw hauv zos yuav tsum tau coj mus rau hauv qhov chaw. Yog tias tsim nyog, kuaj cov kab mob microbiological yuav tsum tau sau thiab txheeb xyuas rau tus kab mob bacteriological rhiab.

Cov Yuav Tsum Muaj

Cov tshuaj no tuaj yeem noj tsuas yog tom qab sab laj nrog kws kho mob thiab kuaj tshuaj. Kev ywj pheej siv cov ntsiav tshuaj ntawm cov tshuaj tsis muaj tshuaj xyuas tuaj yeem pleev cov duab ntawm tus kab mob thiab ua rau nws nyuaj rau kev kuaj mob kom raug.

Flemoklav Solutab 875 + 125 ntsiav tshuaj mg muaj cov contraindications hauv qab no rau kev siv:

Cov tshuaj tiv thaiv tsis haum rau amoxicillin, clavulanic acid, lwm yam tshuaj, tshuaj tua kab mob beta-lactam (piv txwv li penicillins, cephalosporins) hauv anamnesis,
yav dhau los lub sijhawm daj ntseg lossis lub siab ua kom lub siab ua haujlwm thaum siv amoxicillin nrog clavulanic acid hauv keeb kwm
cov menyuam yaus hnub nyoog qis dua 12 xyoos lossis lub cev hnyav dua 40 kg,
lub raum tsis ua haujlwm (qhov ua kom tshem tawm in 30 ml / min).

Nrog kev ceev faj, cov tshuaj hauv cov xwm txheej hauv qab no:

Mob siab heev,
cov kab mob ntawm cov mob hnyuv (suav nrog keeb kwm ntawm colitis cuam tshuam nrog kev siv penicillins),
mob raum tsis ua hauj lwm.

Tsuas tshuaj thiab tswj hwm

Txhawm rau tiv thaiv cov tsos mob dyspeptic, Flemoklav Solutab® yog tus sau tseg thaum pib noj mov. Cov ntsiav tshuaj tau nqos tag nrho, ntxuav nrog ib khob dej, lossis yaj hauv ib nrab khob dej (tsawg kawg 30 ml), nplawm kom huv ua ntej siv.

Txog kev tswj hwm qhov ncauj.

Cov tshuaj noj rau lub cev yog tsim tshwj xeeb raws lub hnub nyoog, lub cev qhov hnyav, lub raum kev ua haujlwm ntawm tus neeg mob, nrog rau qhov mob hnyav heev.

Txoj kev kho yuav tsum tsis txhob txuas ntxiv ntev dua 14 hnub yam tsis muaj tshuaj xyuas qhov xwm txheej kho mob.

Yog tias tsim nyog, nws yog qhov ua tau los ua cov kev kho mob stepwise (thawj kev tswj hwm kev siv tshuaj ntawm cov tshuaj nrog kev hloov mus rau tom kev tswj hwm qhov ncauj).

Lub raum khiav tsis zoo

Ntsiav tshuaj 875 + 125 mg yuav tsum tsuas yog siv rau hauv cov neeg mob uas muaj creatinine tshem tawm ntau dua 30 ml / min, thaum kho cov tshuaj ntau npaum li cas tsis tas yuav tsum tau ua.

Feem ntau, yog tias ua tau, kev kho mob rau cov niam txiv yuav tsum yog qhov zoo dua. Hauv cov neeg mob uas lub raum khiav tsis zoo, kev huam mob tuaj yeem tshwm sim.

Cev xeeb tub

Hauv kev tshawb fawb txog kev ua me nyuam hauv tsiaj, qhov ncauj thiab kev tswj hwm ntawm amoxicillin + clavulanic acid tsis ua rau muaj teebmeem teratogenic.

Hauv txoj kev tshawb fawb ib zaug hauv cov poj niam nrog lub cev ua ntej lub cev xoos xoos, nws tau pom tias kev siv tshuaj kho mob muaj feem cuam tshuam nrog kev pheej hmoo ntawm necrotizing enterocolitis hauv cov menyuam mos yug tshiab. Zoo li txhua yam tshuaj, Flemoklav Solutab® tsis pom zoo siv rau thaum cev xeeb tub, tshwj tsis yog tias cov kev cia siab pab rau leej niam tshaj qhov ua rau muaj kev pheej hmoo rau tus menyuam hauv plab.

Lub sijhawm pub mis niam

Flemoklav Solutab tuaj yeem siv thaum pub niam mis. Dhau ntawm qhov muaj peev xwm ntawm kev nkag siab, mob raws plab, lossis candidiasis ntawm lub qhov ncauj cov leeg ua kab mob cuam tshuam nrog kev nkag mus ntawm cov nyiaj ntawm cov khoom xyaw tseem ceeb ntawm cov tshuaj no rau cov niam mis, tsis muaj lwm yam kev tsis zoo tshwm sim hauv cov menyuam mos lub mis. Thaum muaj qhov tshwm sim tsis zoo hauv cov menyuam yaus noj niam mis, kev pub mis niam yuav tsum tsis tsum.

Sab sij huam

Thaum noj Flemoklav Solutab ntsiav tshuaj hauv cov neeg mob uas lub siab tsis zoo rau kev siv tshuaj, cov kev mob tshwm sim tuaj yeem tsim:

los ntawm cov ntshav hemopoietic plab hnyuv siab raum - thrombocytosis, leukopenia, anemia, thrombocytopenia, agranulocytosis, kev nce prothrombin ntau ntxiv,
los ntawm lub plab zom mov - mob plab, xeev siab, kub siab, ntuav, raws plab, enterocolitis, pseudomembranous mob plab, ua kom mob siab, mob plab hnyuv dysbiosis, kev loj hlob ntawm daim siab tsis ua haujlwm,
los ntawm lub paj hlwb - nriaj, paresthesias, kiv taub hau, chim siab, psychomotor ntxhov siab, pw tsaug zog ntxhov, ntxhov siab,
los ntawm cov kab mob txeeb zig - mob ntawm lub zais zis, tso zis mob tsis tu ncua, interstitial nephritis, kub hnyiab thiab khaus rau qhov chaw mos ntawm cov poj niam,
kev tsis haum - kev tawm pob ntawm daim tawv nqaij, exanthema, urticaria, dermatitis, tshuaj kub taub hau, anaphylactic ceeb, ntshiab ntshav mob,
kev loj hlob ntawm superinfection.

Yog tias ib lossis ntau cov kev mob tshwm sim tshwm sim, koj yuav tsum sab laj nrog kws kho mob kom pab tswv yim; koj yuav tsum tau tsum tsis txhob noj tshuaj nrog ntxiv lawm.

Noj ntau dhau

Cov tsos mob los ntawm kev mob plab thiab cuam tshuam hauv dej-electrolyte sib npaug yuav raug soj ntsuam. Amoxicillin crystalluria tau piav qhia, qee qhov xwm txheej ua rau txoj kev txhim kho lub raum tsis ua haujlwm (saib Ntu "Cov Lus Qhia Tshwj Xeeb thiab Kev Ceeb Toom").

Qhov pom zoo tuaj yeem tshwm sim hauv cov neeg mob uas lub raum tsis ua haujlwm, nrog rau cov neeg uas tau txais tshuaj ntau dua (saib Ntu "Kev Noj Tshuaj thiab Kev Tswj Xyuas" - Cov neeg mob uas lub raum tsis ua haujlwm, "phiv los sis").

Cov tsos mob los ntawm kev mob plab hnyuv yog cov kev kho mob, uas tau them nyiaj tshwj xeeb rau kev ua kom dej-electrolyte sib npaug. Amoxicillin thiab clavulanic acid tuaj yeem tshem tawm cov ntshav tawm los ntawm hemodialysis.

Cov txiaj ntsig ntawm kev soj ntsuam ib txwm muaj nrog 51 tus menyuam ntawm lub chaw tso tshuaj lom tau qhia tias kev tswj hwm ntawm amoxicillin ntawm koob tshuaj tsawg dua 250 mg / kg tsis tau ua rau cov tsos mob tseem ceeb thiab tsis tas yuav ua kom mob plab.

Kev sib cuam tshuam ntawm cov tshuaj nrog lwm cov tshuaj

Nrog rau kev tswj hwm ua ke ntawm cov tshuaj nrog Acetylsalicylic acid lossis Indomethacin, lub sijhawm ntev npaum li Amoxicillin nyob rau hauv cov ntshav thiab cov kua tsib ntau ntxiv, uas ua rau muaj kev pheej hmoo ntawm phiv.

Nrog rau kev siv cov tshuaj Flemoklav ib txhij, solutab nrog antacids, laxatives los yog aminoglycosides txo qis qhov kev nqus ntawm Amoxicillin hauv lub cev, vim tias qhov kev kho tshuaj ntawm cov tshuaj tua kab mob yuav tsis txaus.

Ascorbic acid npaj, ntawm qhov tsis sib xws, nce ntxiv ntawm kev nqus ntawm Amoxicillin hauv lub cev.

Nrog rau kev tswj fwm ntawm Flemoklav ntsiav tshuaj nrog Allopurinol, qhov kev pheej hmoo ntawm cov tawv nqaij ua pob nce.

Nrog rau kev sib cuam tshuam ntawm cov tshuaj Flemoklav Solutab nrog cov tshuaj tua kabmob ua tsis tau, tus neeg mob tau muaj kev pheej hmoo los ntshav.

Qee qhov xwm txheej, nyob rau hauv cov tshuaj, qhov ua tau zoo ntawm kev tiv thaiv qhov ncauj tsawg zuj zus, yog li, cov poj niam uas nyiam hom kev tiv thaiv tsis pub xeeb menyuam yuav tsum ua tib zoo saib thiab siv cov khoom thaiv kev tiv thaiv thaum kho.

Cov lus qhia tshwj xeeb

Cov neeg mob ua rau muaj kev fab tshuaj rau cov tshuaj ua ntej siv Flemoklav solutab, nws yog ib qho tsim nyog yuav tau ua qhov kev ntsuas rhiab, vim tias penicillins feem ntau ua rau ua xua tsis haum. Nrog rau kev txhim kho cov tsos mob ntawm tus mob anaphylaxis lossis angioedema, cov tshuaj tam sim ntawd tau txiav txuas thiab sab laj nrog kws kho mob.

Koj tsis tuaj yeem cuam tshuam ntawm kev kho mob nrog rau cov tshuaj kom sai li sai tau thaum thawj qhov kev txhim kho tus mob tau tshwm sim. Nws yog qhov tseem ceeb rau haus dej haus chav kawm uas tus kws kho mob txog qhov kawg. Kev cuam tshuam kev kho mob ua ntej lub sijhawm tuaj yeem ua rau txhim kho kev tiv thaiv ntawm cov kab mob me me mus rau Amoxicillin thiab kev hloov pauv ntawm tus kabmob mus rau hauv hom mob ntev. Nws tsis pom zoo kom noj cov ntsiav tshuaj ntev dua li lub sijhawm tau teev tseg (tsis pub ntau tshaj 2 lub lis piam), txij li qhov no qhov kev pheej hmoo ntawm kev tsim superinfection thiab exacerbation ntawm tag nrho cov tsos mob ntawm tus kab mob nce. Thaum tsis muaj kev kho mob ntawm cov tshuaj nyob rau hauv 3-5 hnub txij li hnub pib kho, tus neeg mob maj nrawm xav mus ntsib tus kws kho mob kom qhia meej txog kev kuaj mob thiab kho qhov kev kho mob kom raug.

Yog tias mob raws plab tsis tu ncua tshwm sim thaum noj tshuaj thiab txiav mob plab, kev kho mob yuav tsum nres tam sim ntawd thiab tus kws kho mob yuav tsum sab laj, uas yuav ua rau mob plab pseudomembranous.

Cov neeg mob uas muaj mob rau daim siab ntev yuav tsum tau ceev faj tshwj xeeb thaum siv Flemoklav Solutab, txij li thaum siv tshuaj tiv thaiv kab mob los tiv thaiv, kev ua haujlwm ntawm lub cev thiab ua haujlwm hnyav ntxiv tuaj.

Thaum kho cov tshuaj, yuav tsum ceev faj thaum tsav tsheb los yog khoom siv uas yuav tsum tau teb sai. Qhov no yog vim qhov tseeb hais tias thaum kho, cov neeg mob yuav muaj kiv taub hau.

7 ntsiav tshuaj hauv ib lub hlwv, 2 lub hlwv ua ke nrog cov lus qhia rau kev siv raug muab tso rau hauv lub thawv ntawv thawv.

Cov Cai Siv Tshuaj So

Cov tshuaj ntawm cov tshuaj Flemoklav Solutab 875 + 125 los ntawm qhov kev txiav txim ntawm pharmacological yog:

Augmentin ntsiav tshuaj thiab hmoov rau kev ncua
Amoxiclav
Amoxicillin
Flemoxin

Hauv cov khw muag tshuaj hauv Moscow, tus nqi nruab nrab ntawm Flemoklav Solutab 875 + 125 mg ntsiav tshuaj yog 390 rubles. (14 pcs).

Daim ntawv noj tshuaj:

Muaj ib ntsiav tshuaj:

Yam tshuaj muaj sia: amxicillin trihydrate (uas sib haum rau amoxicillin lub hauv paus) - 1019,8 mg (875.0 mg), potassium clavulanate (uas sib raug rau clavulanic acid) -148.9 mg (125 mg).

Cov muaj tswv yim: cellulose dispersed - 30.4 mg, microcrystalline cellulose - 125,9 mg, crospovidone - 64.0 mg, vanillin - 1.0 mg, txiv kab ntxwv qaub tsw qab - 9.0 mg, txiv qaub tsw - 11.0 mg, saccharin - 13, 0 mg, magnesium stearate - 6.0 mg.

Cov ntsiav tshuaj tawg yooj yim ntawm daim ntawv oblong los ntawm dawb mus rau daj, tsis muaj kev pheej hmoo, cim nrog "425" thiab cov duab kab ntawm lub tuam txhab logo. Cov nqaij ntawd yog xim av.

Dosage daim ntawv

Cov ntsiav tshuaj tawg yooj yim 875 mg + 125 mg

Ib ntsiav tshuaj muaj

yam tshuaj: amoxicillin nyob rau hauv daim ntawv ntawm amoxicillin trihydrate

- 875 mg, clavulanic acid nyob rau hauv daim ntawv ntawm poov tshuaj clavulanate - 125 mg.

tus zam: dispersible cellulose, microcrystalline cellulose, crospovidone, vanillin, mandarin tsw, txiv qaub tsw zoo, saccharin, magnesium stearate.

Cov ntsiav tshuaj uas tawg tau los ntawm dawb mus rau daj, oblong, cim "GBR 425" thiab daim duab ntawm cov tuam txhab logo. Brown chaw me ntsis pub

Cov chaw muag tshuaj

Cov Tshuaj Pharmacokinetics

Qhov tsis txaus ntseeg tiag tiag ntawm amoxicillin / clavulanic acid yog 70%. Kev tsis haum yog nyob ywj pheej ntawm kev ua zaub mov. Tom qab txhaj ib zaug xwb ntawm Flemoklav Solutab ntawm ib koob ntawm 875 + 125 mg, qhov siab tshaj plaws ntawm amoxicillin hauv cov ntshav plasma yog tsim tom qab 1 teev, thiab yog 12 μg / ml. Ntshav dej protein khi yog kwv yees li 17-20%. Amoxicillin hla lub cev tso cov nyom thiab hla mus rau leej niam cov kua mis ua kom me me.

Kev daws tag nrho rau ob qho tshuaj yeeb dej caw yog 25 l / h.

Tom qab kev tswj hwm kev mob ntshav, amoxicillin thiab clavulanic acid muaj nyob hauv lub zais zis, lub plab hauv plab, tawv nqaij, rog thiab cov leeg nqaij, hauv cov kua nqaij synovial thiab peritoneal, nrog rau hauv cov kua tsib. Amoxicillin pom nyob rau niam mis.

Amoxicillin thiab clavulanic acid hla qhov chaw tiv thaiv hniav.

Ib nrab-lub neej ntawm amoxicillin thiab clavulanic acid los ntawm cov ntshav cov ntshav hauv cov neeg mob uas lub raum ua haujlwm zoo yog kwv yees li 1 teev (0.9-1.2 teev), hauv cov neeg mob uas muaj creatinine tshem tawm hauv 10-30 ml / min yog 6 teev, thiab nyob rau hauv cov ntaub ntawv ntawm anuria nws txawv ntawm 10 thiab 15 teev. Cov tshuaj yog tawm thaum lub sij hawm hemodialysis.

Li ntawm 60-70% ntawm amoxicillin thiab 40-65% ntawm clavulanic acid raug tso tawm tsis hloov nrog cov zis nyob rau thawj 6 teev.

Cov Tshuaj Hauv Tshuaj

Flemoklav Solutab® - cov tshuaj tua kab mob ntau-spectrum, kev npaj ua ke ntawm amoxicillin thiab clavulanic acid - beta-lactamase inhibitor. Nws ua cov kab mob bactericidal, inhibits kev sib txuas ntawm cov kab mob hauv phab ntsa. Nws ua haujlwm tawm tsam cov kab mob gram-positive thiab gram-tsis zoo (nrog rau cov kev tsim cov kab mob beta-lactamases). Cov clavulanic acid uas yog ib feem ntawm cov tshuaj suppresses hom II, III, IV thiab V hom beta-lactamase, tsis tawm dag zog tiv thaiv hom I beta-lactamases ua Tus kab mob Enterobacter spp., Pseudomonas aeruginosa, Serratia spp., Acinetobacter spp. Clavulanic acid muaj lub siab tropism rau penicillinases, vim tias nws tsim cov chaw ruaj khov nrog cov enzyme, uas tiv thaiv qhov enzymatic degradation ntawm amoxicillin nyob rau hauv kev cuam tshuam ntawm beta-lactamases thiab nthuav nws qhov pom ntawm kev ua.

Flemoklav Solutab® Nws nquag nquag tawm tsam:

Aerobic gram-cov kab mob zoo: Tus kab mob Streptococcus pyogenes, Cov kab mob Streptococcus viridans, Kab mob Streptococcus pneumoniae, Staphylococcus aureus (suav nrog kev tsim cov cab-lactamases), Staphylococcus epidermidis (suav nrog kev tsim cov cab-lactamases), Enterococcus faecalis, Corynebacterium spp., Bacillus anthracis, Listeria monocytogenes,Gardnerellapojniam maum dev

Tus kab mob Anaerobic gram-zoo: Clostridium spp., Peptococcus spp., Peptostreptococcus spp.

Aerobic gram-cov kab mob tsis zoo: Escherichia coli, Klebsiella spp., Proteus mirabilis, Proteus vulgaris, Yersinia enterocolitica, Salmonella spp., Shigella spp., Haemophilus influenzae, Haemophilus duсreyi, Neisseria gonorrhoeae (suav nrog cov kab mob ntawm cov kab mob saum toj no uas tsim cov beta-lactamases), Neisseria meningitidis, Bordetella pertussis, Gardnerella vaginalis, Brucella spp., Branhamella catarrhalis, Pasteurella multocida, Campylobacter jejuni, Vibrio cholerae, Moraxella catarrhalis, Helicobacter pylori.

Anaerobic gram-cov kab mob tsis zoo: Bacteroides spp.suav nrog Bacteroides fragilis,Fusobacteriumspp (suav nrog cov kev uas tsim cov beta-lactamases).

Tsuas tshuaj thiab tswj hwm

Lub sijhawm kho yog nyob ntawm qhov mob hnyav thiab tsis pub tshaj 14 hnub yam tsis muaj kev xav tau tshwj xeeb.

Cov neeg laus thiab menyuam yaus ≥ 40 kg Flemoklav Solyutab® nyob rau hauv ntau npaum

875 mg / 125 mg yog tshuaj 2 zaug ib hnub.

Nrog rau kev kis mob qis dua ntawm qhov ua pa lossis mob otitis, kev siv tshuaj ntau ntxiv tuaj yeem nce txog 3 zaug hauv ib hnub.

Koob tshuaj ib zaug yog muab rau ib ntu, raws li txhua 12 teev.

Txij li 25 mg / 3.6 mg / kg / hnub mus txog 45 mg / 6.4 mg / kg / hnub ob zaug ib hnub.

Txog rau kev kis kab mob hauv cov pa hauv qis lossis kab mob otitis, qhov koob tshuaj yuav raug nce ntxiv txog 70 mg / 10 mg / kg / hnub, 2 zaug ib hnub.

Ntawm cov neeg mob uas lub raum tsis ua haujlwm kev tshem tawm clavulanic acid thiab amoxicillin los ntawm ob lub raum tau qeeb. Flemoklav Solutab® ntawm ib koob ntawm 875 mg / 125 mg tuaj yeem siv tsuas yog ntawm glomerular pom tus nqi> 30 ml / min.

Ntawm cov neeg mob lub siab ua tsis tau haujlwm Flemoklav Solyutab® yuav tsum tau muab tsa nrog kev saib xyuas. Lub siab ua haujlwm yuav tsum tau saib xyuas tas li.