Bagomet - yam tshuaj uas txo cov ntshav qab zib

Raws li cov lus qhia Bagomet yog cov tshuaj hypoglycemic los ntawm pab pawg biguanide. Bagomet tshuaj inhibits gluconeogenesis nyob rau hauv daim siab, pab txo cov piam thaj kev nqus ntawm cov hnyuv. Cov tshuaj no pab txhawb kev siv lub zog ntawm cov kua nplaum ntev, ua kom muaj kev cuam tshuam ntawm cov nqaij mos rau cov tshuaj insulin. Kev txheeb xyuas txog Bagomet paub meej tias cov tshuaj no ua haujlwm zoo li qub thiab txawm tias txo lub cev qhov hnyav.

Kev Qhia Txog Bagomet

Raws li Bagomet cov lus qhia, cov kws kho mob tau sau ntawv rau cov neeg mob ntshav qab zib hom 2 tsis muaj ketoacidosis. Bagomet yog noj yog tias kev noj zaub mov noj thiab kho nrog sulfonylureas tau pom tias tsis muaj txiaj ntsig hauv kev kho. Cov tshuaj Bagomet yog noj hauv monotherapy lossis kev sib xyaw nrog insulin lossis lwm tus neeg mob hypoglycemic.

Tsuas tshuaj thiab tswj hwm

Raws li cov lus qhia Bagomet tau coj ntawm qhov ncauj. Nws yuav tsum tau yug los rau hauv lub siab tias qhov koob tshuaj ntawm lub tshuaj yuav tsum tau teeb tsa los ntawm tus kws kho mob tshwj xeeb, nyob ntawm seb cov concentration ntawm cov piam thaj hauv cov ntshav ntawm tus neeg mob. Bagomet tuaj yeem noj ua ntej thiab tom qab noj mov.

Yog tias cov neeg mob tsis noj tshuaj insulin, Bagomet ntsiav tshuaj tuaj yeem yuav haus ib hnub ob zaug rau 1 gram. Nws kuj tseem yuav tsum tau noj cov tshuaj hauv thawj peb hnub ntawm kev kho mob. Koj tuaj yeem haus raws li lwm cov qauv - ib ntsiav tshuaj ntawm Bagomet 500 mg peb zaug ib hnub. Txij hnub plaub, cov qauv pauv, koj yuav tsum noj ob lub hnab tshuaj Bagomet peb zaug ib hnub. Yog li ntawd kom txog thaum kaum plaub hnub, suav nrog. Tom qab qhov no, kuaj ntshav thiab tso zis rau ntawm cov piam thaj. Txij li kaum tsib hnub, qhov kev noj tshuaj ntawm kev noj tshuaj Bagomet tau hloov kho. Qhov koob tshuaj txhua hnub yuav tsum yog 1-2 g.

Yog tias tus neeg mob muaj 850 mg Bagomet ntsiav tshuaj, lawv yuav tsum tau noj ob zaug ib hnub, ib zaug zuj zus. Koj yuav tsum nco ntsoov tias txog li peb gram ntawm Bagomet yuav tsum tau noj nyob rau ntau hnub.

Nrog txoj kev tswj hwm thooj txhij ntawm Bagomet thiab insulin, tus neeg mob yuav tsum tau txo cov koob tshuaj insulin. Ntau cov lus pom zoo dua rau kev txais tos zoo li no yuav tsum raug muab los ntawm kws kho mob.

Sab Sij Huam Bagomet

Kev txheeb xyuas txog Bagomet hais tias cov tshuaj muaj peev xwm ua rau muaj kev phiv ntau yam. Tus neeg mob yuav hnov ​​ntuav thiab raws plab, mob plab thaum siv tshuaj. Qee zaum siv Bagomet ua rau muaj kev saj ntawm cov hlau hauv qhov ncauj. Cov tshuaj kuj tuaj yeem muab cov kev phiv ntxiv: ua rau lub cev tsis muaj zog, ua kom lub cev tsis zoo hauv qab los noj mov, ntshav qab zib. Lub caij nyoog siv ntawm Bagomet ua rau ntau tshaj ntawm cov vitamin B12 hauv tib neeg lub cev.

Cov Yuav Tsum Muaj

Raws li cov lus qhia Bagomet tsis tuaj yeem noj nrog hypersensitivity rau metformin. Cov tshuaj yog contraindicated nyob rau hauv lub raum tsis ua hauj lwm, mob ntshav qab zib coma, precoma, ketoacidosis. Bagomet tsis tseem coj mus rau kev ua pa thiab lub plawv tsis ua haujlwm, mob plawv nres, mob cerebrovascular mob hnyav. Bagomet yog categorically contraindicated nyob rau hauv ntev cawv. Tsis tas li, cov kws kho mob tsis tau qhia kom noj cov tshuaj no tom qab raug mob thiab ua haujlwm hnyav. Kev tshuaj xyuas ntawm Bagomet hais tias nws tsis pom zoo kom noj cov tshuaj rau cov neeg mob tom qab rau caum xyoo.

Pharmacological cov yam ntxwv ntawm Bagomet

Bagomet yog ib qho tshuaj hypoglycemic uas ua rau ob qho tib si ceev cov piam thaj thiab qhov ua tau zoo tom qab noj mov. Cov tshuaj tsis cuam tshuam rau kev tsim ntawm cov tshuaj insulin. Ntawm cov kev mob tshwm sim ntawm cov neeg mob ntshav qab zib tsis yog kho. Cov kev kho mob muaj peev xwm tshwm sim tom qab lub inhibition ntawm glycogenolysis thiab gluconeogenesis, uas ua rau inhibition ntawm glycogen nyob rau hauv daim siab.Qhov tshuaj pab rau cov hlwb kom ntes thiab tso cov piam thaj, ntxiv qhov rhiab ntawm peripheral receptors rau cov tshuaj hormones, thiab inhibits qhov nqus ntawm carbohydrates los ntawm cov hnyuv phab ntsa.

Bagomet txhim kho qhov ua tau zoo ntawm cov enzyme uas ua kom nrawm dua ntawm cov khoom sib xyaw ntawm glycogen, ua rau muaj peev xwm thauj tau ntau dua ntawm cov khoom siv membrane ntawm cov kua nplaum. Cov tshuaj kho cov lipid metabolism - nrog hom 2 ntshav qab zib muaj txoj hmoo ua kom poob phaus.

Bagomet muab piv nrog lub peev xwm sib xyaw kom zoo thiab qhov kev zom sai.

Thaum noj, cov tshuaj tam sim ntawd nqus los ntawm lub plab zom mov, qhov siab tshaj plaws tau mus txog hauv ob thiab ib nrab teev. Ua rau kom qis li qhov ua tau ntawm cov tshuaj txuam thaum tau txais zaub mov. Bagomet cov kev ntsuas kev nyab xeeb yog mus txog 60% ntawm tag nrho cov tshuaj ntawm cov tshuaj xa mus rau cov kabmob.

Raws li cov txiaj ntsig ntawm kev tshawb fawb pharmacokinetic, peb tuaj yeem xaus tias cov tshuaj sai sai rau ntawm cov ntaub so ntswg, ua kom muaj hauv plasma. Cheebtsam ntawm cov tshuaj tsis khi rau cov protein, nws tuaj yeem nkag mus rau hauv cov ntshav liab, tab sis hauv cov ntshav lawv muaj tsawg dua piv rau ntshav.

Cov kev sim tau paub tseeb tias cov tshuaj tsis tau metabolized hauv lub cev - lub raum nws zoo nws nyob hauv nws lub xeev qub. Hauv qhov no, ib nrab-lub neej yog rau thiab ib nrab hnub teev. Bagomet tawm tawm yog qhov kev xav los ntawm kev ua haujlwm siab glomerular pom thiab lub raum plab tsis pom kev, yog li ntawd, txhua tus neeg mob nrog lub raum pathologies yog qhov muaj kev pheej hmoo.

Ib nrab-lub neej tau nce, uas txhais tau tias muaj kev pheej hmoo ntawm kev txuam nrog tshuaj.

Kev ntsuas qhov tseeb thiab txoj kev siv

Bagomet yog npaj rau kev kho mob rau cov neeg mob ntshav qab zib nrog insulin-ywj siab hom kab mob thiab kev rog (hauv qhov tsis muaj ketoacidosis thiab kev tsis txaus teb rau kev kho mob nrog sulfonylureas).

Kev siv Bagomet yog ua tau tsuas yog raws li cov lus pom zoo ntawm tus neeg endocrinologist, uas yuav piav qhia txog kev kho mob coj mus rau hauv tus account qhov mob hnyav thiab kev noj qab haus huv ntawm tus neeg mob.

Cov tshuaj yog npaj rau kev siv sab hauv. Nqos cov ntsiav tshuaj kom tag nrho nrog dej. Qhov no feem ntau tshwm sim nrog cov zaub mov lossis tam sim ntawd tom qab nws. Kev muab tshuaj thawj zaug yog 500-100 mg / hnub, nyob ntawm qib glycemia. Koj tuaj yeem hloov kho tsuas yog tom qab ob lub lim tiam ntawm kev nquag thiab kev saib xyuas ntawm glycemic ntsuas.

Yog tias tus kws kho mob tsis tau txiav txim siab txog tus neeg mob txog tus neeg mob, tom qab ntawd tus qauv muab tshuaj kho tau yog li ntawm 1500 txog 2000 mg. Nws yog tsis yooj yim sua kom dhau qhov siab tshaj plaws kev coj ua. Yog tias cov tshuaj provokes kev quav ntawm cov quav, koj tuaj yeem tsoo qhov kev cai niaj hnub los ntawm 2-3 zaug.

Nrog cov kev kho mob nyuaj "Bagomet ntxiv rau cov tshuaj insulin npaj", cov qauv tshuaj yog 1500 mg / hnub. Rau cov ntsiav tshuaj nrog lub peev xwm ncua ntev, qhov qib siab zoo rau txhua hnub yog 850 mg -1000 mg. Nrog kev muaj peev xwm tiv taus ib txwm, lawv nres ntawm kev saib xyuas ntawm 1700 mg / hnub., Txwv - 2550 mg / hnub. Nrog txoj kev kho mob nyuaj nrog lwm cov tshuaj rau cov ntshav qab zib, ib ntsiav tshuaj (850 mg lossis 100 mg) yog tshuaj.

Hauv kev laus, Bagomet noj tsis ntau tshaj 1000 mg / hnub. Koj tuaj yeem muab tshuaj rau cov menyuam yaus hnub nyoog 10 xyoo. Cov menyuam yaus, nrog rau cov laus, yuav tsum pib ib chav kho mob nrog 500-850 mg / hnub. Hauv cov menyuam yaus, qhov tshuaj ntau tshaj txhua hnub yog 2000 mg.

Sab sij huam

Feem ntau, cov tshuaj tau raug pom zoo los ntawm cov neeg mob feem ntau, tab sis, zoo li ib yam tshuaj twg, nws tuaj yeem muaj kev mob tshwm sim.

Cov kev soj ntsuam ua ntej pom tau hais tias Bagomet tsis cuam tshuam rau mutagenicity, carcinogenicity thiab teratogenicity. Nws tsis cuam tshuam ntawm kev ua me nyuam muaj qhov ua pov thawj.

Qhia Txog Tshuaj Yeeb

Bagomet's hypoglycemic muaj peev xwm txhim kho los ntawm sulfonamides, insulin, acarbose, tshuaj tsis-steroidal anti-inflammatory tshuaj, ACE thiab MAO inhibitors, oxytetracycline, β-blockers.

Glucocorticosteroids, GOK, epinephrine, glucagon, cov tshuaj tiv thaiv qog, cov tshuaj qog ntshav, sympathomimetics, thiazide thiab "voj" diuretics, derivatives ntawm phenothiazine thiab nicotinic acid inhibit nws txoj haujlwm.

Qhov kev tshem tawm ntawm Bagomet los ntawm cov plab hnyuv siab raum yog tiv thaiv los ntawm cimetidine. Anticoagulant muaj peev xwm ntawm Coumarin derivatives inhibits Bagomet.

Siv dej cawv txuam lactic acidosis. Nws cov tsos mob yog qhov kev poob qis hauv lub cev kub, myalgia, tsis xis nyob hauv lub plab, mob plab tsis ua hauj lwm, mob plab, tso quav tsis muaj zog, tsaus muag. Ntawm thawj qhov kev ua xyem xyav, tus neeg raug mob pw hauv tsev kho mob thiab kev kuaj mob kom meej meej los ntawm kev kuaj xyuas qhov concentration ntawm lactate hauv cov plab hnyuv siab raum thiab cov ntaub so ntswg. Raws li kev qhia, nws yog ntxiv los ntawm kev kho mob.

Tshaj tsos mob

Yog hais tias cov koob tshuaj ntawm Bagomet yog saum toj no cov kev tso cai ntau tshaj plaws, cov kab mob lactic acidosis nrog rau qhov tshwm sim loj tshaj plaws hauv daim ntawv ntawm kev tsis nco qab thiab txawm tuag taus yog ua tau. Cov txiaj ntsig zoo sib xws yog tshwm sim los ntawm kev nce siab ntawm cov tshuaj hauv lub cev muaj teeb meem nrog nws cov zis tawm los ntawm lub raum. Qhov teeb meem loj tuaj hauv ob peb teev thiab xa nrog cov yam ntxwv ntawm tus yam ntxwv:

• Dyspeptic mob
• Kev Ntshav Qab Zib,
• Ua txhaum ntawm cov lus sib dhos ntawm lub plab hnyuv,
• Mob hauv plab
• Neej Hmoob
• Plam kev sib koom tes
• Tsaus muag thiab mob plab tso dag.

Yog tias tsawg kawg ib feem ntawm cov tsos mob tau tshwm sim, Bagomet yuav tsum tau kho kom sai, thiab tus neeg raug mob yuav tsum tau mus pw hauv tsev kho mob.

Tso tawm daim ntawv, muaj pes tsawg leeg, chaw cia khoom

Cov ntsiav tshuaj tuaj yeem muaj cov duab thiab xim sib txawv, nyob ntawm qhov ntau npaum li cas: dawb, puag ncig thiab convex - 500 mg txhua qhov, nyob rau hauv daim ntawv ntawm cov tshuaj ntsiav 850 mg bluish hauv xim thiab 1000 mg hauv dawb. Cov yav tas muaj lub zog ntev. Qhov tshwj xeeb ntawm daim ntawv tso tawm yog cov kab sib faib thiab cov chaw tsim khoom lub logo, embossed ntawm txhua cov ntsiav tshuaj.

Ib ntsiav tshuaj muaj los ntawm 500 txog 100 mg ntawm cov tshuaj ua kom nquag plias metformin hydrochloride ntxiv rau cov neeg tsis paub nyob rau hauv daim ntawv ntawm croscarmellose sodium, povidone, stearic acid, pob kws hmoov txhuv, lactose monohydrate.

Cov khoom siv xub ntiag nrog cov tshuaj yuav tsum tau muab tso rau hauv qhov chaw uas cov menyuam yaus nkag tsis tau, txog rau qhov kub txog 25 ° C. Khaws Bagomet tsis pub dhau ob xyoos.

Cov lus ua piv txwv thiab analogues tshuaj

Bagomet synonyms suav nrog cov tshuaj uas ob pawg (tshuaj tiv thaiv kab mob hauv qhov ncauj) thiab cov nquag ua ke (metformin) coincide.

Bagomet's analogs yog cov tshuaj nyob rau hauv uas tsawg kawg ib tus kab mob lossis kev mob sib txig sib luag hauv cov lus tim khawv, nyob rau hauv rooj plaub no hom 2 ntshav qab zib.

1. Av ‡ Q
2. Apidra
3. Baeta
4. Glemaz
5. Glidiab
6. Glucobay,
7. Ntujnrim,
8. Lymphomyozot,
9. Levemir Penfill,
10. Levemir Flekspen,
11. Multisorb,
12. Metamine
13. NovoFormin,
14. Pioglar
15. Txog rau cov,
16. Rau menyuam yaus.

Nrog cov kev kho mob nyuaj nrog lwm cov tshuaj ntawm cov txiaj ntsig zoo sib xws, nws yog ib qho tseem ceeb uas yuav tsum xav txog qhov muaj peev xwm txo tus mob ntshav qab zib tsawg. Cov tshuaj muaj peev xwm ua kom muaj kev cuam tshuam kev sib koom tes thiab txo cov tshuaj psychomotor qeeb, yog li thaum ua haujlwm nrog cov txheej txheem lossis thaum tsav tsheb, nws zoo dua rau qhov tsis kam noj tshuaj. Kev siv Bagomet koom nrog txoj cai yuav tsum tau ua raws nrog cov zaub mov muaj carb tsawg uas tswj kev noj cov carbohydrates hauv cov ntshav.

Kev txheeb xyuas txog Bagomet

Txog ntawm cov tshuaj Bagomet, kev tshuaj xyuas ntawm kws kho mob feem ntau yog qhov zoo. Raws li cov kws tshaj lij, kev noj tshuaj xws li cov tshuaj yeeb tshuaj no muaj peev xwm tswj cov ntshav qab zib nyob ntev li 12 teev. Cov sijhawm zoo no lav nws qee yam zoo: koj tuaj yeem txo qhov tsawg zaus ntawm kev noj tshuaj, txhim kho kev soj ntsuam ntawm cov txheej txheem hauv metabolic. Tib lub sijhawm, kev nqus ntawm cov khoom ua kom nquag plias los ntawm kev zom zaub mov tau zoo tuaj thiab txoj kev pheej hmoo ntawm kev tsim cov kev mob tshwm sim yog tsawg.

Cov neeg mob tseem nco tau muaj cov tshuaj: ntawm Bagomet tus nqi (850 mg ntim) tsuas yog 180-230 rubles rau 60 ntsiav tshuaj. Tso cov tshuaj rau hauv khw muag tshuaj nrog rau cov tshuaj noj.

Cov lus piav qhia txog cov tshuaj tsis tuaj yeem ua ib daim ntawv qhia rau kev siv. Ua ntej yuav khoom, koj yuav tsum sab laj nrog cov kws kho mob endocrinologist, thiab ua ntej noj tshuaj Bagomet, nyeem cov lus qhia rau kev siv los ntawm tus tsim khoom. Cov ntaub ntawv hais txog Bagomet yog muab rau kev paub dav dav nrog nws lub peev xwm thiab tsis yog kev qhia rau kev kho tus kheej. Kev noj tshuaj zoo rau tus kab mob ntshav qab zib, suav txog qhov mob ntshav qab zib, mob ntshav qab zib thiab cov kab mob kev noj qab haus huv ntawm cov ntshav qab zib, tsuas yog tsim los ntawm tus kws tshwj xeeb.