NYIAM

Glycidone thiab glipizide - Cov neeg sawv cev ntawm cov tshuaj muaj ntshav qab zib los ntawm sulfonylurea pab pawg. Glycidone lossis glipizide ua li cas thiab qee kis li cas? Koj yuav pom cov lus teb hauv tsab xov xwm hnub no. Nyob zoo cov phooj ywg! Niaj hnub no kuv xav ua kom tiav tham txog cov tshuaj ntawm sulfonylurea pab pawg, tab sis tsis yog hais txog kev txo cov tshuaj muaj suab thaj hauv feem ntau, vim tias tseem muaj ob peb pab pawg uas tsis tau txais kev pom zoo los ntawm kuv mloog.

Raws li koj nco, Kuv twb sau txog cov neeg sawv cev ntawm cov pab pawg coob hauv cov lus "Diabeton MV lossis Gliclazide", "Glimepiride kho mob ntshav qab zib hom 2", thiab hais txog maninil hauv tsab xov xwm "Cov piam thaj txo cov tshuaj hauv lub neej ntawm tus neeg mob ntshav qab zib," yog tias yog koj tsis tau nyeem dua, kuv thov koj.

Glycvidone thiab glipizide tsis yog cov tshuaj nrov heev rau kev kho mob ntshav qab zib mellitus feem ntau. Lawv suav hais tias yog tshuaj nrog qhov ua kom txo qis qab zib, txawm hais tias cov txheej txheem ntawm kev ua ntawm glycidone thiab glipizide zoo ib yam li cov neeg muaj zog dua: mannil lossis ntshav qab zib. Ntawd yog, lawv tseem txhawb nqa pancreatic beta hlwb, txhim kho cov tshuaj insulin zais cia. Ob qho tshuaj no tsis tshua muaj tshuaj kho mob monotherapy, feem ntau yog ib feem ntawm kev sib xyaw ua ke.

Tau kawg, cov npe "glycidone", "glipizide" yog cov khoom lag luam thoob ntiaj teb uas tsis muaj, thiab hauv cov khw muag tshuaj koj tuaj yeem pom lawv nyob hauv qab lwm cov npe kev lag luam twb tau.

Glycvidone = Glenrenorm

Glycvidone feem ntau pom nyob rau hauv lub npe Glyurenorm, tab sis koj tuaj yeem nrhiav cov tshuaj uas muaj lub npe zoo thoob ntiaj teb. Muaj nyob rau hauv cov ntsiav tshuaj ntawm koob tshuaj 30 mg. Thawj koob tshuaj yog 1/2 ntsiav tshuaj hauv ib hnub, tom qab ntawd cov koob tshuaj thiab / lossis cov thawj coj ntawm cov thawj coj tau nce siab dua. Qhov siab tshaj plaws ntawm glurenorm yog 4 ntsiav tshuaj hauv ib hnub (120 mg / hnub). Cov tshuaj tau noj 30 feeb ua ntej noj mov, tso cai rau nws kom nqus thiab nthuav nws cov nyhuv. Lub ncov ntawm kev nqis tes ua tshwm sim ntawm qhov siab ntawm kev nqus khoom noj - tom qab 1.5-2 teev, sijhawm ua haujlwm yog li 8-10 teev.

Qhov txawv txav ntawm glycidone yog tias nws yuav luag tag nrho cov zaub mov hauv lub siab thiab ua rau hauv plab hnyuv. Los ntawm lub raum, tsuas yog 5% ntawm cov tshuaj tau tawm hauv, uas tso cai rau cov neeg mob raum tsis ua haujlwm siv nws nrog zoo tsis muaj kev ntshai.

Txij li thaum cov tshuaj muaj cov nyhuv uas tsis tshua muaj zog, nws tuaj yeem siv rau hauv thawj theem pib mob ntshav qab zib mellitus kev kho mob rau cov neeg mob tsis muaj qhov hnyav dhau, thaum cov ntshav qabzib hauv lub siab tsis siab heev. Yog hais tias glurenorm yog qhov ua tsis tau zoo, lwm yam tshuaj los ntawm pab pawg no tau raug sau, lossis nws hloov los ntawm cov tshuaj los ntawm lwm pawg.

Zoo li txhua yam tshuaj rau ntshav qab zib, glycidone muaj qhov sib npaug sib npaug:

• ntshav qab zib hom 1
• cev xeeb tub
• kev pub mis
• ketoacidosis lossis ketoacidotic coma

• hypoglycemia (cov ntshav qabzib tsawg)
• xeev siab ntuav
• tsis qab los noj mov
• kev fab tshuaj tsis haum
• leukopenia
• mob taub hau

Glipizide = minidiab

Koj tuaj yeem nrhiav glipizide hauv cov khw muag tshuaj raws li lub npe "minidiab" lossis "glibenesis." Cov ntsiav tshuaj nws tus kheej yog tshwj xeeb. Qhov no yog cov ntsiav tshuaj nrog kev tswj hwm tso tawm ntawm cov tshuaj nquag, i.e., cov tshuaj nquag - glibenesis, maj mam tso tawm, dhau ntawm txoj hnyuv ntev, yog li muab qhov txo qis hauv cov ntshav qab zib thiab cov nyhuv ntev dua. Ib qho zoo sib xws yog pom nyob hauv ntshav qab zib mellitus.

Glipizide muaj nyob rau hauv 5 mg ntsiav tshuaj. Nws pib ua haujlwm tom qab 15-30 feeb, yog li nws tseem ceeb nws yuav tsum noj 15-30 feeb ua ntej noj. Qhov siab tshaj plaws yog tom qab 1.5-2 teev, nyob twj ywm hauv cov ntshav kom txog 20 teev. Cov nyhuv raug kwv yees li 2 teev tom qab noj mov nrog lub ntsuas ntshav hauv tsev.

Pib noj tshuaj 5 mg ib hnub twg, maj mam nce raws qib ntawm glycemia. Qhov siab tshaj plaws niaj hnub noj tshuaj yog nce mus txog 40 mg. Qhov koob tshuaj txhua hnub tuaj yeem faib ua 2-3 koob.

Cov kev tsis haum thiab cov kev mob tshwm sim zoo ib yam li cov glycidone (glurenorm).

Raws li kuv twb tau hais, cov tshuaj no ua haujlwm zoo heev hauv kev sib txuas nrog lwm cov tshuaj tiv thaiv kev puas tsuaj los ntawm lwm pab pawg. Piv txwv, nws yog qhov zoo nrog metformin, ntau npaum ntawm qhov tau txiav txim los ntawm tus kws kho mob, zoo li thiosalidinedione (actos, avandium) lossis insulin.

Feem ntau, qhov no yog txhua yam kuv xav hais txog glycidone thiab glipizide. Nrog txoj kev paub no, koj tuaj yeem ntsuas qhov ua tau zoo ntawm cov tshuaj uas siv thiab, yog tias tsis muaj txiaj ntsig, hloov nws mus rau cov tshuaj uas muaj zog. Yuav kom ncaj ncees, Kuv tsis tshua tau kws kho cov tshuaj no, ntau heev qee qhov mob ntshav qab zib.

Tab sis nyob hauv cov cheeb tsam sib txawv nrog kev xa khoom nyob rau hauv ntau txoj kev, nws yog li ntawd tau hais tias ntxiv nrog rau lawv koj tsis muaj dab tsi ntau dua los xaiv kws kho mob. Nws tshwm sim tias cov tshuaj no haum koj zoo thiab cov ntshav qab zib cov ntshav yuav nyob ruaj khov, tom qab ntawd koj yuav tsum tsis txhob saib qhov zoo ntawm qhov zoo, tab sis maj mam haus cov tshuaj no.

Los ntawm txoj kev, Kuv kiag li tsis nco qab tawm ib qhov txuas rau ib tsab xov xwm hais txog cov tshuaj tshiab tshaj plaws rau cov ntshav qab zib rau cov neeg uas tsis tau nyeem thiab tig tawm los yog thawj zaug ntawm blog. Tsab ntawv xov xwm no yog "Qhov Lus Cog Tseg Ua Qhia Txog Kev Kho Mob Ntshav Qab Zib."

Koj nyiam qhov twg ntawv? Kuv yuav zoo siab heev yog tias koj qhia nws rau koj cov phooj ywg los ntawm cov kev pabcuam pejxeem. Kev koom tes sib pab kom cov muaj kev tu ncua, ib yam li koj, tau txais cov ntaub ntawv tseem ceeb ntsig txog ntshav qab zib. Rau koj kom yooj yim, hauv qab tsab xov xwm muaj cov nyees khawm ntawm cov kev sib raug zoo tshaj plaws. tes hauj lwm ntawm lub teb chaws uas koj yuav rau npe.

Nrog kev sov siab thiab kev saib xyuas, tus kws kho mob endocrinologist Dilara Lebedeva

Pharmacological kev txiav txim

Glipizide - tus neeg sawv cev ntawm qhov ncauj hypoglycemic, hais txog sulfonylurea derivatives ntawm II tiam. Pab tsim cov tshuaj insulin tso tawm los ntawm beta-endocrinocytes ntawm tus txiav, nce qhov tso tawm ntawm insulin.

Tsub kom cov ntaub so ntswg rhiab rau insulin. Nws muaj hypolipidemic, fibrinolytic cov yam ntxwv, inhibits platelet aggregation. Qhov kev txiav txim pib 10-30 feeb tom qab noj cov tshuaj.

Hom 2 mob ntshav qab zib mellitus (nrog rau qhov tsis muaj txiaj ntsig ntawm kev noj zaub mov noj).

Thov

Cov koob tshuaj tau teeb tsa ib leeg zuj zus nyob ntawm saib daim duab soj ntsuam kab mob. Thawj koob tshuaj txhua hnub yog 2.5-5 mg. Qhov siab tshaj plaws ntau npaum li cas yog 15 mg. Qhov nyiaj pab ntau tshaj txhua hnub yog 45 mg. Qhov ntau zaus ntawm kev tswj hwm yog 2-4 r / hnub 30 feeb ua ntej noj mov.

Thaum sau tshuaj rau glipizide tom qab siv cov tshuaj insulin lossis lwm yam kev tiv thaiv hypoglycemic, kev noj sai ntawm glipizide hauv cov ntshav yuav tsum txiav txim siab thiab qhov tshuaj yuav tsum tswj hwm raws li theem ntawm glycemia 2-4 r / hnub hauv thawj 4-5 hnub. Nrog rau kev txhim kho cov ntshav qog ntshav qab zib, yog tias tus neeg mob nco qab, qabzib (lossis kua qab zib) yog tshuaj hauv.

Yog tias tsis nco qab, tso ntshav qabzib lossis glucagon sc, intramuscularly lossis intravenously raug tswj hwm. Tom qab nws rov qab nco qab, nws yog ib qho tsim nyog yuav tsum tau muab rau cov neeg mob zaub mov nplua nuj nyob hauv cov khoom noj kom paub zoo kom tsis txhob rov qab txhim kho kev mob hypoglycemia. Nrog rau kev raug mob, mob hnyav, kev phais mob ntau ntxiv, tus neeg mob yuav tsum pauv mus rau kev siv cov tshuaj insulin.

Sab sij huam

- Tsis tshua muaj ntshav siab - hypoglycemia (tshwj xeeb tshaj yog rau cov neeg laus, cov neeg mob uas tsis muaj zog, nrog rau kev noj zaub mov tsis xwm yeem, haus cawv, ua rau lub siab thiab lub raum tsis ua haujlwm), cov tsos mob dyspeptic, mob taub hau, uas ploj nrog koob tshuaj hloov kho.

- Daim tawv nqaij ARs tshwm sim tsis tshua muaj, muaj tus cim hloov chaw, kev tshem tawm tshuaj tsis tas yuav tsum muaj.
- Nws yog tsawg - hematopoiesis.

Cov ntaub ntawv dav dav txog kev quav yeeb tshuaj

Qhov kev tivthaiv no yog tus neeg sawv cev hluavtaws hypoglycemic.

Glipizide tsis tuaj yeem yaj nyob rau hauv dej los yog dej cawv, txawm li cas los xij, ib qho kev daws teeb meem NaOH (0.1 mol / L concentration) thiab dimethylformamide yaj ua qhov feem no zoo. Qhov tshuaj yeeb tshuaj no yog tsim tawm hauv cov ntsiav tshuaj uas zoo sib xws thiab txhawb nqa cov ntsiav tshuaj tawm.

Thaum ib qho tshuaj nkag mus rau hauv lub cev ntawm cov ntshav qab zib, nws txhawb nqa kev tso tawm ntawm cov kua dej los ntawm kev ua haujlwm beta hlwb ntawm islet apparatus.

Glipizide ua raws li hauv qab no:

1. Txo cov piam thaj thiab glycosylated hemoglobin ntawm lub plab khoob.
2. Ua kom muaj qabzib ntxiv, thiab tseem ua rau qee yam me me - tshem tawm cov kua dawb dawb.
3. Txo cov ntxim nyiam ntawm hyperglycemia tom qab noj mov.

Cov tshuaj tiv thaiv tsis cuam tshuam rau cov lipid metabolism. Nws ua kom nws pib tom qab 30 feeb ntawm kev pub nkag thiab txuas ntxiv txhua hnub. Qhov siab tshaj plaws ntawm cov tshuaj pom tau yog tom qab 1-3 teev ntawm kev siv lub qhov ncauj.

Nws yuav tsum raug sau tseg tias Glipizide yog qhov zoo dua tsis siv thaum noj mov, vim tias nws qhov kev nqus tag nrho poob qis. Biotransformation ntawm cov tshuaj tshwm sim hauv lub siab.

Qhov feem cuam yog tawm ua cov metabolite nrog rau quav thiab tso zis, suav nrog tsis hloov pauv - txog 10%.

Cov lus qhia rau kev siv

Ua ntej siv cov kev npaj muaj glipizide, koj yuav tsum sab laj tus kws kho mob lossis tus kws kho mob endocrinologist. Tsuas yog ib tus kws kho mob thiaj li tuaj yeem rau kwv yees uas tsim nyog ntawm kev siv lub cuab yeej tshwj xeeb.

Tom qab yuav cov tshuaj, koj yuav tsum ua tib zoo nyeem phau ntawv qhia. Qhov tshuaj thawj zaug yog 5 mg, uas tau muab tshuaj ib hnub ua ntej lossis tom qab noj mov. Sij hawm dhau mus, nrog rau tus mob ntshav qab zib ib txwm muaj kev noj qab haus huv, kev noj tshuaj tuaj yeem maj mam nce mus rau 15 mg, faib cov thawj coj ntawm cov tshuaj ntau zaus.

Cov lus qhia tau hais tias yog tias cov koob tshuaj tau ploj lawm, tab sis ob peb teev dhau los txij li qhov tsim nyog tsim nyog, cov tshuaj yuav tsum tau muab tshuaj sai sai. Tab sis yog tias yuav luag ib hnub tau dhau los, koj yuav tsum ua raws li kev coj noj coj ua.

Cov neeg mob ntawm lub hnub nyoog qib siab thiab kev txom nyem los ntawm daim siab pathology yuav tsum siv cov tshuaj hauv qhov tsawg kawg nkaus - 2.5 mg ib hnub twg, thiab lub caij nyoog ntev-tso cov ntsiav tshuaj - los ntawm 5 mus rau 10 mg ib zaug, nyiam dua thaum sawv ntxov.

Zoo li txhua lwm yam tshuaj, Glipizide yuav tsum muab tso kom deb ntawm cov menyuam yaus hauv qhov chaw tiv thaiv los ntawm cov av noo ntawm chav tsev kub.

Cov txheej txheem sib tsoo thiab cov phom sij uas yuav muaj

Qee yam mob ntshav qab zib siv tsis tau cov tshuaj no.

Cov lus qhia muaj contraindications ntsig txog tus neeg mob rhiab rau cov tshuaj, mob ntshav qab zib tsis nco qab, insulin-hom mob ntshav qab zib, ketoacidosis, kub taub hau, kev phais tsis ntev los no, cev xeeb tub thiab lub sijhawm pub mis niam.

Hauv cov xwm txheej hnyav tshwj xeeb, kev siv Glipizide tuaj yeem siv tau thaum yug menyuam. Tab sis nws siv yuav tsum tau tso tseg 1 lub hlis ua ntej hnub yug.

Thaum lub sij hawm pub mis niam, noj cov tshuaj yog nruj me ntsis txwv tsis pub.

Tus kws kho mob qhov kev sab laj ua ntej siv Glipizide yuav tsum, vim kev tswj hwm tsis raug cai ntawm cov tshuaj tuaj yeem ua rau ntau qhov kev tsis txaus siab:

• mob taub hau, tsis meej pem, nkees, mob leeg nraus, mob ntshav qab zib, dias taub hau, kev nyuaj siab, mob taub hau, ntxhov siab, qhov muag thiab pom pob txha,
• flatulence, xeev siab, ntuav, impurities ntawm cov ntshav nyob rau hauv cov quav, cem quav, dyspepsia thiab anorexia,
• khaus, pob thiab khaus,
• pharyngitis, rhinitis thiab dyspnea,
• txuam nrog cov hlab plawv thiab cov ntshav tsim: arrhythmia, syncope, cia li kub flashes thiab kub siab,
• kuj yog glycemia hauv hom 2 mob ntshav qab zib mellitus mus txog glycemic coma.
• ntsig txog kab mob genitourinary system: txo qis kev sib deev muaj siab thiab dysuria.

Tsis tas li ntawd, qee qhov kev mob tshwm sim ntxiv - nriaj, tsis nqhis dej tsis txaus, myalgia, mob caj pas, tawm hws, mob ib ce.

Nqi, tshuaj xyuas thiab analogues

Txij li thaum glipizide yog ib qho kev ua haujlwm, ntau yam tshuaj muaj cov tshuaj muaj peev xwm nrhiav tau ntawm cov khw muag tshuaj ntawm Lavxias. Piv txwv, Glucotrol CL thiab Glibenez Retard. Nyob ntawm daim ntawv tso tawm, tus nqi ntawm cov tshuaj Glucotrol CL thaj tsam ntawm 280 txog 360 rubles, thiab Glibenez Retard - los ntawm 80 txog 300 rubles.

Kev txheeb xyuas ntawm cov neeg mob ntshav qab zib feem ntau uas tau noj cov tshuaj no yog qhov txaus siab. Txawm li cas los xij, ntau yam tau sau tseg tias qhov kev kho mob ntawm glipizide poob qis dua lub sijhawm, yog li nws feem ntau siv nrog lwm cov tshuaj mob ntshav qab zib. Ntawm qhov zoo ntawm cov tshuaj tuaj yeem paub qhov txawv yooj yim ntawm kev siv thiab tus nqi siab ntawm cov tshuaj muaj glipizide.

Nyob rau hauv rooj plaub thaum thaum ib cov tshuaj tsis haum vim yog contraindications los yog tsis zoo, tus kws kho mob sau ib qho tshuaj analogue. Cov tshuaj no suav nrog:

Yog tias tsis pom zoo los ntawm tus kws kho mob, kev noj tshuaj rau tus kheej tsis tsim nyog. Kev npaj muaj glipizide tuaj yeem muaj kev cuam tshuam tsis zoo rau tib neeg lub cev. Nrog rau kev siv tshuaj zoo, koj tuaj yeem ua kom cov piam thaj kom zoo li qub thiab tshem tawm cov tsos mob ntshav qab zib. Tab sis kuj peb yuav tsum tsis txhob hnov ​​qab txog kev kho kev qoj ib ce rau ntshav qab zib thiab kev noj zaub mov kom zoo.

Hauv cov yeeb yaj kiab hauv tsab xov xwm no, kws kho mob yuav tham txog tshuaj kho ntshav qab zib.

Kws Tshuaj

Tsim kho kev tsim tawm cov insulin los ntawm kev ua haujlwm ntawm pancreatic beta cells. Nws txo qis theem ntawm glycosylated hemoglobin thiab yoo cov kua nplaum cov ntshav tsis haum rau cov neeg mob uas muaj mob hnyav thiab hnyav ntawm cov mob ntshav qab zib tsis yog-insulin-mellitus. Txo cov zaub mov tom qab cov zaub mov hyperglycemia, nce qabzib kam rau ua thiab tshem tawm cov kua dej dawb (mus rau qhov tsawg). Cov tshuaj insulinotropic teb tshwm sim tsis pub dhau 30 feeb tom qab kev tswj hwm ntawm qhov ncauj, lub sijhawm ua nrog kev txhaj ib zaug txog 24 teev. Nws tsis cuam tshuam qhov lipid profile ntawm cov ntshav ntshav.

Hauv kev sim tshuaj nas thiab nas ntawm koob tshuaj 75 zaug ntau dua li MPD, nws tsis ua rau mob carcinogenesis thiab tsis cuam tshuam rau qhov kev muaj menyuam (cov nas). Cov kev kawm ua rau cov kab mob, thiab hauv vivo , tsis tau qhia lub zog mutagenic.

Daim ntawv foos nrawm yog nqus tau sai thiab ua tiav. Noj mov tsis cuam tshuam rau qhov nqus tag nrho, tab sis ua rau nws qeeb rau 40 feeb. C_max txiav txim siab li 1-3 teev tom qab ib koob nkaus xwb. T_1/2 yog 2–4 teev. Tom qab noj daim ntawv qeeb-ua yeeb yam, nws tshwm hauv cov ntshav tom qab 2-3 teev, C_max Nws tau ncav cuag tom qab 6-12 teev. Nws khi rau cov ntshav cov ntshav protein li ntawm 98–99%. Qhov ntim ntawm kev faib tawm tom qab kev tswj hwm yog 11 L, nruab nrab T_1/2 - 2-5 teev .Txais Cl tom qab kev txhaj tshuaj ib zaug yog 3 l / teev. Biotransformed hauv lub siab (nrog rau thawj nqe lus - me ntsis). Tsawg dua 10% yog pom tsis hloov pauv hauv cov zis thiab cov quav, li 90% yog tso tawm hauv daim ntawv ntawm cov roj ntsha nrog cov zis (80%) thiab cov quav (10%).

Cov kev mob tshwm sim ntawm cov tshuaj Glipizide

Rau qhov ua yeeb yam qeeb ntawm glipizide:

Los ntawm cov leeg hlwb thiab cov haujlwm hauv lub cev: kiv taub hau, mob taub hau, pw tsaug zog, tsaug zog, ntxhov siab, kev nyuaj siab, ntxhov siab, gait cuam tshuam, kab mob khaub thuas, hypersthesia, daim ntaub thaiv nyob rau hauv pem hauv ntej ntawm lub qhov muag, mob qhov muag, pom pob txha, mob raum.

Los ntawm cov hlab plawv system thiab ntshav (hematopoiesis, hemostasis): syncope, arrhythmia, ntshav tawm ntshav siab, qhov paub ntawm kub flashes.

Los ntawm sab ntawm cov metabolism: ntshav qog.

Los ntawm cov hnyuv: anorexia, xeev siab, ntuav, ib qho kev xav ntawm qhov hnyav hauv thaj chaw epigastric, dyspepsia, cem quav, admixture ntawm cov ntshav hauv cov quav.

Ntawm feem ntawm daim tawv nqaij: xoo pob, urticaria, khaus.

Los ntawm tus txheej txheem ua pa: rhinitis, pharyngitis, dyspnea.

Los ntawm genitourinary system: mob plab, tsis muaj libido.

Lwm yam: nqhis dej, tshee hnyo, peripheral edema, tsis muaj qhov mob thoob plaws lub cev, mob caj dab, mob leeg ntshav, mob ib ce, tawm hws.

Rau daim ntawv ua nrawm nrawm nrawm ntawm glipizide:

Los ntawm cov leeg hlwb thiab cov haujlwm hauv lub cev: mob taub hau, kiv taub hau, tsaug zog.

Los ntawm cov hlab plawv system thiab ntshav (hematopoiesis, hemostasis: leukopenia, agranulocytosis, thrombocytopenia, pancytopenia, hemolytic lossis aplastic anemia.

Los ntawm sab ntawm cov metabolism: ntshav qab zib insipidus, hyponatremia, kab mob porphyrin.

Los ntawm cov hnyuv: xeev siab, ntuav, mob epigastric, cem quav, cholestatic kab mob siab (daj tawv nqaij thiab sclera, tshem tawm cov quav thiab tso zis dub, mob rau hauv txoj cai hypochondrium).

Ntawm feem ntawm daim tawv nqaij: erythema, pob tw daj maculopapular, urticaria, photosensitivity.

Lwm yam: nce nyob rau hauv kev mloog ntawm LDH, alkaline phosphatase, indil bilirubin.

Kev sib txuam

Cov ntxhia thiab glucocorticoids, amphetamines, anticonvulsants (hydantoin derivatives), asparaginase, baclofen, calcium antagonists, carbonic anhydrase inhibitors (acetazolamide), chlortalidone, tshuaj tiv thaiv qhov ncauj, epinephrine, ethacinic acid, giurimide, thymoside, thymegium. cov qog, triamteren thiab lwm yam tshuaj uas ua rau hyperglycemia. Cov tshuaj anabolic steroids thiab androgens txhim kho hypoglycemic. Indirect anticoagulants, NSAIDs, chloramphenicol, clofibrate, guanethidine, MAO inhibitors, probenecid, sulfonamides, rifampicin nce kev ua si ntawm cov roj ntsha dawb hauv cov ntshav (vim kev txav tawm los ntawm kev sib txuas nrog cov protein ntshav) thiab ua kom lub zog biotransformation. Ketonazole, miconazole, sulfinpyrazone thaiv kev tsis sib luag thiab nce rau kev mob ntshav siab. Tawm tsam cov keeb kwm yav dhau los ntawm kev haus cawv, muaj kev txhim kho ntawm disulfiram-zoo li mob syndrome (mob plab, xeev siab, ntuav, mob taub hau) tau. Antithyroid thiab tshuaj myelotoxic ntau ntxiv tuaj yeem txhim kho agranulocytosis, tom kawg, ntxiv rau - thrombocytopenia.

Noj ntau dhau

Kev Kho Mob: kev tshem tawm yeeb tshuaj, ntshav qabzib thiab / lossis kev hloov pauv ntawm kev noj zaub mov nrog qhov yuav tsum tau saib xyuas glycemia, nrog cov ntshav qog ntshav qab zib tsawg (tsis nco qab, qaug dab peg) - kev mus pw hauv tsev kho mob tam sim, kev tswj hwm ntawm 50% cov ntshav qabzib nyob nrog kev sib txig sib luag (iv dej) ntawm 10% kev daws Cov piam thaj txhawm rau kom muaj ntshav qabzib cov ntshav siab siab tshaj 5.5 mmol / l, kev kuaj xyuas glycemia yog tsim nyog rau 1-2 hnub tom qab tus neeg mob tawm hauv lub cev tsis xeev. Kev lim ntshav yog qhov ua tsis zoo.