Kev Siv Tshuaj Insulin Bazal GT

Ncua rau lub subcutaneous tswj ntawm 100 IU / ml

1 ml ntawm kev tshem tawm muaj

cov tshuaj nquag - tib neeg cov tshuaj insulin 100 IU (3,571 mg),

tus zam: 85% glycerol, protamine sulfate, metacresol, phenol, zinc chloride, sodium hydrogen phosphate dihydrate, sodium hydroxide, concentrated hydrochloric acid, dej rau kev txhaj tshuaj.

Sai dispersing kev ncua ntawm dawb los yog yuav luag dawb. Tus supernatant yog pob tshab lossis yuav luag pob tshab.

Cov chaw muag tshuaj

Cov Tshuaj Pharmacokinetics

Neeg tsis ntseeg xav® Basal GT (isofan-insulin ncua kev kawm) yog insulin nrog maj mam tsim tawm thiab ntev ua. Tom qab tswj hwm subcutaneous, cov nyhuv tshwm sim li ntawm 60 feeb, theem ntawm kev ua siab tshaj plaws pom tau 3-4 teev tom qab txhaj, cov nyhuv ntev li 11-20 teev.

Ib nrab-lub neej ntawm insulin los ntawm ntshav dej yog li 4-6 feeb. Nws yog lub sijhawm ntev dua nyob rau hauv lub raum tsis ua haujlwm. Nws yuav tsum raug sau tseg tias pharmacokinetics ntawm insulin tsis cuam tshuam nws cov nyhuv metabolic.

Cov Tshuaj Hauv Tshuaj

Neeg tsis ntseeg xav® Basal HT muaj insulin zoo sib xws hauv kev teeb tsa rau tib neeg insulin, tau los ntawm kev siv DNA thev naus laus zis siv Escherichia coli.

Neeg tsis ntseeg xav® Bazal GT

- txo cov ntshav qabzib thiab txhawb cov teebmeem anabolic, thiab kuj txo cov teebmeem catabolic

- txhim kho kev thauj cov kua nplaum mus rau hauv cov hlwb, nrog rau kev tsim cov glycogen hauv cov leeg thiab mob siab, txhim kho kev siv pyruvate. Nws inhibits glycogenolysis thiab glyconeogenesis

- txhim kho lipogenesis nyob rau hauv daim siab thiab adipose ntaub so ntswg thiab inhibits lipolysis

- txhawb kev noj cov amino acids los ntawm lub hlwb thiab ua kom muaj protein ntau ua ke

- Kev noj cov poov tshuaj ntau ntxiv los ntawm cov cell.

Tsuas tshuaj thiab tswj hwm

Cov ntshav qabzib xav tau ntau, cov tshuaj insulin yuav siv thiab kev noj tshuaj ntau npaum li cas (koob tshuaj, faib lub sijhawm) tau xaiv ib tus zuj zus raws li kev noj haus, theem kev ua haujlwm thiab kev ua neej ntawm tus neeg mob.

Cov koob tshuaj txhua hnub thiab lub sijhawm ntawm thawj coj

Nws tsis muaj txoj cai dab tsi pauv rau kev noj tshuaj insulin. Qhov nruab nrab txhua hnub xav tau insulin yog 0.5-1.0 IU ib kg ntawm tus neeg mob lub cev qhov hnyav. Qhov yooj yim metabolic xav tau rau cov tshuaj insulin yog 40-60% ntawm qhov xav tau txhua hnub. Neeg tsis ntseeg xav® Bazal GT raug tswj subcutaneously 45-60 feeb ua ntej noj mov.

Hloov kho koob thib ob

Txhim kho kev tswj kev zom zaub mov tuaj yeem ua rau muaj peev xwm tiv thaiv insulin ntau dua, ua rau cov tshuaj insulin qis dua. Hloov tshuaj yuav tsum yog muaj kev hloov pauv hauv tus neeg mob lub cev qhov hnyav, kev ua neej, thiab lwm yam uas yuav ua rau muaj kev pheej hmoo rau lub qog ntshav qab zib lossis hyperglycemia (saib "Cov Lus Qhia Tshwj Xeeb").

Cov pab pawg neeg tshwj xeeb

Qhov xav tau ntawm cov tshuaj insulin tuaj yeem txo thaum muaj teeb meem ntawm daim siab thiab lub raum thiab thaum lub hnub nyoog laus (saib "Cov lus qhia tshwj xeeb").

Kev muab tshuaj rau hauv qhov quav yog kiag li cais tawm.

Neeg tsis ntseeg xav® Basal GT raug tswj subcutaneously.

Qhov nqus ntawm insulin thiab, vim li ntawd, cov suab thaj txo qis ntawm kev txhaj tshuaj tuaj yeem sib txawv, nyob ntawm qhov chaw txhaj tshuaj (piv txwv li, lub plab phab ntsa piv rau thaj tsam poj niam). Qhov chaw txhaj tshuaj yuav tsum tau hloov pauv txhua zaus hauv thaj chaw.

Cov Tshuaj Hauv Tshuaj

Insuman ® Basal GT muaj cov tshuaj insulin zoo ib yam hauv cov qauv rau tib neeg insulin thiab tau los ntawm kev tsim kho caj ces siv cov tshuaj tua neeg Escherichia coli K12 135 pINT90d.

Tus txheej txheem ntawm kev ua ntawm insulin:

Txo cov concentration ntawm cov piam thaj hauv cov ntshav, txhawb cov teebmeem anabolic thiab txo cov teebmeem catabolic,

Nws nce cov piam thaj hauv kev kho hauv cov hlwb thiab kev tsim cov glycogen hauv cov leeg thiab daim siab thiab txhim kho kev siv pyruvate, inhibits glycogenolysis thiab glyconeogenesis,

Muaj lipogenesis ntau nyob rau hauv daim siab thiab adipose nqaij thiab inhibits lipolysis,

Txhawb nqa qhov khiav ntawm cov amino acids rau hauv cov hlwb thiab cov synthesis ntawm protein,

Nce potassium ntxiv rau hauv lub hlwb.

Insuman ® Bazal GT yog cov tshuaj insulin ntev ntev nrog kev maj mam pib ntawm kev ua. Tom qab kev tswj hwm sc, cov nyhuv hypoglycemic tshwm sim hauv 1 teev thiab nce mus txog qhov siab tshaj plaws nyob rau hauv 3-4 teev. Cov nyhuv tseem mob rau 11-20 teev.

Cov Yuav Tsum Muaj

cov tshuaj tiv thaiv tsis haum rau insulin lossis rau ib qho twg ntawm cov tshuaj, tshwj tsis yog kev kho tshuaj insulin tseem ceeb heev,

Nrog saib xyuas: Mob raum tsis ua hauj lwm (muaj peev xwm txo qis hauv insulin vim qhov qis hauv insulin metabolism), cov neeg laus laus (kev ua haujlwm hauv lub raum tsawg zuj zus tuaj yeem ua rau muaj qis zuj zus ntxiv hauv insulin thov), daim siab tsis ua haujlwm (xav tau insulin tuaj yeem txo vim muaj qis zuj zus ntawm gluconeogenesis muaj peev xwm thiab txo qis cov tshuaj insulin metabolism), mob hnyav rau cov hlab ntshav tawm ntawm lub cev thiab cov hlab ntsha hauv hlwb (hauv cov neeg mob no, cov ntshav qog ntshav qis yuav muaj cov kab mob tshwj xeeb, i.e. K. muaj kev pheej hmoo ntawm lub plawv lossis mob hlwb ntau dua ntawm cov ntshav qog ntshav qab zib), cov neeg mob qog ntshav siab, tshwj xeeb tshaj yog cov uas tsis tau txais kev kho mob nrog photocoagulation (kho laser), vim tias nrog hypoglycemia muaj kev pheej hmoo ntawm kev hloov chaw amaurosis - ua tiav qhov muag tsis pom, cov neeg mob uas muaj cov kabmob sib kis (vim hais tias cov kabmob sib kis feem ntau xav tau cov tshuaj insulin).

Yog tias tus neeg mob muaj ib qho ntawm cov kabmob no lossis cov xwm txheej, koj yuav tsum sab laj nrog koj tus kws kho mob ua ntej siv cov tshuaj.

Cev xeeb tub thiab lactation

Kev kho mob nrog Insuman ® Basal GT thaum cev xeeb tub yuav tsum txuas ntxiv. Cov tshuaj Insulin tsis hla qhov chaw tiv thaiv. Kev tswj kom zoo ntawm kev tswj lub cev zom zaub mov thoob plaws lub cev xeeb tub yuav tsum muaj rau cov poj niam uas muaj ntshav qab zib ua ntej cev xeeb tub, lossis rau cov poj niam uas tau muaj tus mob ntshav qab zib tsis tsaug zog.

Qhov kev xav tau rau insulin thaum cev xeeb tub tuaj yeem txo qis hauv thawj peb lub hlis thaum cev xeeb tub thiab feem ntau nce nyob rau lub sijhawm thib ob thiab thib peb ntawm kev xeeb tub. Tam sim ntawd tom qab yug los, xav tau insulin tsawg dua (muaj kev pheej hmoo ntawm cov ntshav qog ntshav qab zib tsawg dua). Thaum cev xeeb tub thiab tshwj xeeb tshaj yog tom qab yug menyuam, yuav tsum ua tib zoo saib xyuas ntawm cov ntshav qabzib hauv cov ntshav.

Yog tias koj cev xeeb tub los yog npaj lub cev xeeb tub, nco ntsoov qhia koj tus kws kho mob.

Thaum lub sijhawm pub niam mis, tsis muaj kev txwv dab tsi rau kev kho tshuaj insulin, txawm li cas los xij, kev siv tshuaj insulin thiab kev noj haus yuav raug tsim nyog.

Sab sij huam

Kev ntshav siab. Feem ntau cov kev mob tshwm sim ntawm kev siv tshuaj insulin tuaj yeem tsim kho yog tias cov koob tshuaj insulin tau tshaj qhov xav tau ntawm nws (saib "Cov Lus Qhia Tshwj Xeeb"). Kev rov qab mob ceev dua ntawm cov ntshav qog ua rau mob ntshav qab zib tuaj yeem ua rau txoj kev mob puas siab ntsws ntawm lub cev, nrog rau tsis nco qab, tu cev (saib "Overdose"). Lub caij nyoog ntev los sis mob ceev heev ntawm cov ntshav qab zib hauv lub siab tuaj yeem tsim kev hem thawj rau neeg txoj sia.

Hauv ntau tus neeg mob, cov tsos mob thiab cov tsos mob ntawm tus mob neuroglycopenia ua ntej los ntawm cov tsos mob ntawm tus mob reflex (hauv kev teb rau kev txhim kho hypoglycemia) kev ua haujlwm ntawm lub siab xav ntawm lub hlwb. Feem ntau, nrog hais tawm ntau dua los yog nrawm dua qub nyob rau hauv kev mloog zoo ntawm cov piam thaj hauv cov ntshav, qhov tshwm sim ntawm kev rov ua dua ntawm lub siab xav ntawm lub cev thiab nws cov tsos mob tshwm sim ntau dua.

Nrog qhov kev txo qis hauv cov concentration ntawm cov piam thaj hauv cov ntshav, kev txhim kho ntawm hypokalemia (muaj teeb meem los ntawm CCC) lossis kev txhim kho ntawm cerebral edema tau.

Cov hauv qab no yog cov kev tshwm sim tsis zoo uas tau pom nyob hauv cov chaw kho mob uas tau faib los ntawm cov chav kawm hauv lub cev thiab hauv kev ua kom muaj kev poob qis: muaj ntau heev (/1 / 10), ntau zaus (≥1 / 100 thiab Tshiab, uas endocrinologist qhia rau Saib Xyuas Ntshav Qab Zib Ntxiv! Nws tsuas yog tsim nyog txhua hnub.

Cov tshuaj no yog cov khoom lag luam ntawm Sanofi, uas ua kom nrov npe Lantus, Apidra thiab Tujeo. Insuman cov koom nrog hauv kev lag luam insulin yog li 15%. Raws li cov neeg mob ntshav qab zib, txoj kev daws teeb meem yooj yim mus siv, tus cwj pwm los ntawm lub siab zoo tsis tu ncua. Muaj ob hom tshuaj insulin hauv kab: nruab nrab Insuman Bazal thiab luv luv Insuman Rapid.

Cov tshuaj ua haujlwm li cas?

Insuman yog lub noob caj noob ces ua haujlwm insulin tib neeg. Ntawm kev ntsuas kev lag luam, qhov tshuaj tiv thaiv yog tsim los siv cov kab mob. Piv nrog insulins siv yav tas los, kev tshuaj ntsuam genetic engineering muaj ntau qhov ua haujlwm ruaj khov thiab zoo tu.

Sij hawm dhau los, lub hom phiaj ntawm kev kho tshuaj insulin yog los tawm tsam kev tuag. Nrog kev tshwm sim ntawm tib neeg insulin, qhov kev sib tw tau hloov pauv. Tam sim no peb tab tom hais txog kev txo cov kev pheej hmoo ntawm cov kev mob nyhav thiab tag nrho lub neej ntawm cov neeg mob. Tau kawg, kom ua tiav qhov no ntawm cov tshuaj insulin tau yooj yim dua, tab sis ntawm Insuman ruaj khov nyiaj mob ntshav qab zib yog tau. Txhawm rau ua qhov no, koj yuav tsum ua tib zoo nyeem cov lus qhia rau qhov tshuaj, nws qhov profile ntawm kev ua, kawm thiab kho nws kom raws sijhawm.

Mob ntshav qab zib thiab siab surges yuav yog ib yam dhau los

Mob ntshav qab zib yog qhov ua rau ze li ntawm 80% ntawm tag nrho cov cwj nrag thiab txiav taws. 7 ntawm 10 leej neeg tuag vim txhaws ntawm cov hlab ntsha hauv plawv lossis paj hlwb. Yuav luag txhua qhov teeb meem, qhov laj thawj rau qhov txaus ntshai kawg no yog qhov qub - ntshav qab zib siab.

Cov piam thaj tuaj yeem thiab yuav tsum tau sib khob, tsis muaj dab tsi. Tab sis qhov no tsis kho tus kab mob nws tus kheej, tab sis tsuas yog pab txhawm rau txhawm rau tshawb xyuas, thiab tsis yog qhov ua kom muaj tus kab mob.

Cov tshuaj nkaus xwb uas raug pom zoo rau mob ntshav qab zib thiab siv los ntawm endocrinologist hauv lawv txoj haujlwm yog Ji Dao Diabetes Adhesive.

Qhov ua tau zoo ntawm cov tshuaj, suav raws li tus qauv txheej txheem (tus naj npawb ntawm cov neeg mob uas tau zoo mus rau tag nrho cov neeg mob hauv pawg 100 ntawm cov neeg tau txais kev kho mob) yog:

• Li qub ntawm qab zib - 95%
• Kev tshem tawm ntawm cov hlab ntsha thrombosis - 70%
• Ntaus tau ntawm lub plawv dhia muaj zog - 90%
• Kev tshem tawm ntshav siab - 92%
• Ntxiv dag zog rau nruab hnub, txhim kho pw tsaug zog thaum hmo ntuj - 97%

Ji Dao cov neeg tsim khoom tsis yog lub koom haum ua lag luam thiab tau nyiaj los ntawm lub xeev. Yog li ntawd, tam sim no txhua tus neeg nyob hauv nroog muaj txoj cai yuav tau txais cov tshuaj ntawm tus nqi luv 50%.

Qhov kev sib txuas ntawm cov tshuaj hormone hauv txoj hlab ntshav zoo tsis ruaj khov. Qhov tso tawm insulin tseem ceeb tshwm sim hauv kev teb rau cov piam thaj mus rau hauv cov hlab ntshav los ntawm cov khoom noj. Txawm li cas los xij, yog tias ib tus neeg tau tshaib plab lossis pw tsaug zog, tseem muaj cov tshuaj insulin nyob rau hauv cov ntshav, txawm hais tias muaj ntau qhov ntau me me - ntawm qhov thiaj li hu ua theem pib. Thaum cov khoom lag luam lawm nres nrog cov ntshav qab zib, kev hloov pauv kho tau pib. Qhov no feem ntau xav tau 2 hom insulin. Theem qib pib ua raws li Insuman Bazal, nws nkag rau hauv cov ntshav maj mam, ntev ntev thiab hauv qhov me me. Cov piam thaj tom qab noj mov tau tsim los txo Insuman Rapid, uas ncav cuag cov hlab ntsha ntau dua.

Cov yam ntxwv sib piv ntawm Insumans:

Kev thov cov cai

Qhov xav tau tshuaj insulin yog ib leeg rau ib qho mob ntshav qab zib. Raws li txoj cai, cov neeg mob uas muaj hom 2 thiab kev rog yog xav tau ntau yam tshuaj hormones. Raws li cov lus qhia rau kev siv, nruab nrab ib hnub, cov neeg mob tau txhaj li 1 pawg ntawm cov tshuaj ib kilogram ntawm qhov hnyav. Daim duab no suav nrog Insuman Bazal thiab nrawm. Cov tshuaj insulin luv luv rau 40-60% ntawm qhov xav tau tag nrho.

Insuman Bazal

Txij thaum Insuman Bazal GT ua haujlwm tsawg dua ib hnub, koj yuav tsum nkag rau nws ob zaug: thaum sawv ntxov tom qab ntsuas cov suab thaj thiab ua ntej yuav mus pw. Koob tshuaj rau txhua cov tswj hwm tau muab cais cais. Rau qhov no, muaj cov txheej txheem tshwj xeeb uas coj mus rau hauv tus account rhiab rau cov ntaub ntawv hormone thiab glycemia. Txoj kev tsim nyog yuav tsum nce siab txog qib qab zib nyob rau lub sijhawm thaum tus neeg mob ntshav qab zib tau tshaib plab.

Insuman Bazal yog qhov raug tshem tawm, thaum lub sijhawm khaws nws exfoliates: cov kua ntshiab tseem nyob rau saum toj, dawb nag lossis daus nyob hauv qab. Ua ntej txhua txoj kev txhaj tshuaj, cov tshuaj hauv koob txhaj tshuaj yuav tsum sib xyaw kom zoo Cov. Qhov niaj hnub zoo ib yam li qhov raug ncua kev kawm ntawv zuj zus mus, yuav siv cov tshuaj ntau dua kom tiav. Insuman Bazal yooj yim dua los npaj rau kev tswj hwm dua li lwm cov insulins nruab nrab. Txhawm rau kom yooj yim sib xyaw, lub pob laub yog nruab nrog peb lub pob, uas ua rau nws ua tiav qhov homogeneity zoo ntawm kev ncua nyob rau hauv tsuas yog 6 lem ntawm koob txhaj tshuaj.

Npaj yuav siv Insuman Bazal muaj xim dawb xim. Ib qho cim ntawm kev puas tsuaj rau tshuaj yog flakes, muaju, thiab blotches ntawm cov xim sib txawv hauv lub taub ntim tom qab sib tov.

Insuman Sai Sai

Luv Insuman Rapid GT txhaj ua ntej noj mov, feem ntau ib hnub peb zaug. Nws pib ua haujlwm tom qab 30 feeb, yog li kev txhaj tshuaj yuav tsum tau ua ua ntej. Txhawm rau txhawm rau txhim kho cov nyiaj mob ntshav qab zib, nws yog ntshaw kom tau txais qhov sib txig ntawm qhov tau txais ntawm feem ntawm insulin thiab piam thaj hauv cov ntshav.

Ua li no, koj xav tau:

1. Pib koj cov pluas noj nrog cov carbohydrates qeeb thiab muaj protein ntau. Cov carbohydrates nrawm yog sab laug thaum noj mov kawg.
2. Noj me ntsis ntawm cov zaub mov tseem ceeb. Rau ib qho khoom noj txom ncauj, 12-20 g ntawm carbohydrates yog qhov txaus.

Qhov koob tshuaj ntawm Insuman Rapid yog txiav txim siab los ntawm tus nqi ntawm cov carbohydrates hauv cov zaub mov thiab cov khoom noj txom ncauj tom qab. Kev suav qhov tseeb tso cai rau koj tshem tawm los ntawm cov hlab ntsha tag nrho cov piam thaj uas nrog zaub mov noj.

Cov roj ntsha insulin yog ib txwm pob tshab, koj tsis tas yuav sib xyaw nws, daim phwj syringe tuaj yeem siv tsis tau npaj.

Cov txheej txheem txhaj tshuaj

Insuman yog tsim los ntawm tus tsim nyob rau hauv daim ntawv ntawm 5 ml vials, 3 ml cartridges thiab syringe cwjmem. Hauv cov chaw muag tshuaj Lavxias, nws yooj yim mus yuav ib cov tshuaj tso rau hauv SoloStar koob txhaj tshuaj. Lawv muaj 3 ml ntawm insulin thiab tsis tuaj yeem siv tom qab cov tshuaj dhau lawm.

Yuav ua li cas sau Insuman:

1. Txhawm rau kom txo qhov mob ntawm kev txhaj tshuaj thiab txo qhov kev pheej hmoo ntawm lipodystrophy, cov tshuaj nyob rau hauv cov xaum xaum yuav tsum nyob ntawm chav tsev kub.
2. Ua ntej siv, daim cartridge tau ua tib zoo tshuaj xyuas cov cim ntawm kev puas tsuaj. Yog li kom tus neeg mob tsis yuam kev lub hom insulin, koob txhaj tshuaj yog cov cim xim nrog cov xim sib dhos sib haum xim ntawm cov ntawv sau rau ntawm pob. Insuman Bazal GT - ntsuab, ceev ceev GT - daj.
3. Insuman Bazal yog dov ntawm cov xib teg ob peb zaug los sib tov.
4. Ib rab koob tshiab raug muab rau txhua txoj kev txhaj tshuaj. Siv rov qab ua rau lub cev puas tsuaj tuaj. Txhua koob xav tau zoo li SoloStar koob txhaj tshuaj: MicroFine, Insupen, NovoFine thiab lwm yam. Qhov ntev ntawm lub koob yog xaiv nyob ntawm qhov tuab ntawm cov subcutaneous rog.
5. Cov xwj syringe tso cai rau koj ntaus ntawm 1 txog 80 chav. Ntsuas tshuaj, ntsuas qhov tseeb - 1 ntsuas. Hauv cov menyuam yaus thiab cov neeg mob ntawm cov zaub mov uas tsis muaj carbohydrate tsawg, qhov kev xav tau cov tshuaj hormones tuaj yeem yog qhov tsawg heev, lawv yuav tsum muaj qhov tseeb ntau dua nyob rau hauv cov chaw noj tshuaj. SoloStar tsis haum rau cov teeb meem zoo li no.
6. Insuman Rho nrawm dua li qhov kev xaiv hauv plab, Insuman Bazal - hauv tus ncej lossis pob tw.
7. Tom qab qhia cov tshuaj, rab koob tau tso rau hauv lub cev rau 10 feeb ntxiv kom cov tshuaj tsis pib xau.
8. Tom qab siv txhua lub sijhawm, rab koob tau tawm. Cov tshuaj insulin ntshai tsam tshav ntuj, yog li koj yuav tsum tau kaw tus cartridge nrog lub hau.

Sab sij huam

Yog tias cov tshuaj siv tau ntau dua li qhov xav tau, nws tshwm sim. Nws yog nws yog qhov feem ntau cov kev mob tshwm sim los ntawm kev siv tshuaj insulin, tsis hais qhov twg ntawm kev siv tshuaj insulin. Kev mob ntshav qab zib tsawg tuaj yeem ua rau mob sai sai, yog li txawm tias cov kua qab zib tsawg dua li qub yuav tsum tau muab tshem tawm sai sai.

Qhov tshwm sim ntawm Insuman kuj suav nrog:

Tus kws kho mob ntawm Kev Tshawb Fawb Kev Kho Mob, Lub Taub Hau ntawm Lub Tsev Kawm ntawm Diabetology - Tatyana Yakovleva

Kuv tau kawm mob ntshav qab zib tau ntau xyoo. Nws yog txaus ntshai thaum muaj coob tus neeg tuag, thiab haj yam ua rau neeg xiam vim ntshav qab zib.

Kuv maj nrawm nroos los qhia txoj xov zoo - Endocrinological qhov chaw tshawb fawb ntawm Lavxias Academy ntawm Medical Science tau tswj los tsim cov tshuaj uas kho cov ntshav qab zib kom tiav. Thaum lub sijhawm, cov hauj lwm zoo ntawm cov tshuaj no tau nce mus txog 98%.

Lwm qhov xov xwm zoo: Lub Tsev Haujlwm Saib Xyuas Kev Noj Qab Haus Huv tau txais kev nyab xeeb qhov kev saws me nyuam ntawm cov haujlwm tshwj xeeb uas them rau cov nqi tshuaj ntau. Hauv Lavxias, neeg mob ntshav qab zib kom txog rau thaum lub Plaub Hlis 23 (suav nrog) tuaj yeem tau txais nws - Tsuas yog 147 rubles!

1. Kev tsis haum rau cov feem ntawm kev daws. Feem ntau nws qhia nyob rau hauv khaus, liab, tawm pob xoo hauv thaj chaw ntawm thawj coj. Ntau heev tsawg dua (raws li cov lus qhia, tsawg dua 1%) kev ntsuas tus mob tshwm sim: bronchospasm, edema, siab poob, poob siab.
2. Kev tuav cia Sodium. Feem ntau nws pom thaum pib kho, thaum qab zib los ntawm tus lej siab poob rau qhov qub. Hypernatremia yog nrog los ntawm edema, ntshav siab, nqhis dej, txob taus.
3. Kev tsim cov tshuaj tiv thaiv rau insulin hauv lub cev yog cov yam ntxwv ntawm kev kho insulin mus ntev. Hauv qhov xwm txheej no, ib qho kev nce ntxiv hauv koob tshuaj Insuman yog qhov yuav tsum tau ua. Yog tias cov koob xav tau ntau dhau lawm, tus neeg mob hloov mus rau lwm hom tshuaj insulin lossis immunosuppressive tshuaj yog kws kho.
4. Cov kev txhim kho hauv ntshav qab zib txaus ntshai tuaj yeem ua rau tsis pom kev ib ntus.

Feem ntau, lub cev maj mam dhau los siv cov insulin, thiab cov tshuaj tiv thaiv ua xua. Yog tias ib qho tshwm sim dhau los yog kev phom sij txog lub neej (anaphylactic shock) lossis tsis ploj tom qab 2 lub lis piam, nws raug nquahu kom hloov cov tshuaj nrog tshuaj analog. Insuman Bazal GT - lossis, Sai GT -, lossis Humulin Tsis Txaus. Cov tshuaj no sib txawv tsuas yog nyob rau hauv excipients. Qhov txiav txim profile yog tib yam rau lawv. Thaum ua xua rau tib neeg cov kua dej, lawv hloov mus rau insulin analogues.

Insuman tus nqi yog kwv yees li qhov sib npaug ntawm tus nqi ntawm nws cov se. Cov tshuaj rau hauv lub phwj pwj xwb raug nqi li 1100 rubles. rau ib 15 ml (1500 units, 5 xee kua roj). Isofan-insulin muaj nyob rau hauv cov npe tseem ceeb tshuaj, yog li cov neeg mob ntshav qab zib muaj lub peev xwm los txais nws dawb .

Cov lus qhia tshwj xeeb

Kev mob ntshav qab zib yog qhov tshwm sim hnyav tshaj plaws ntawm kev kho mob insulin, yog li ntawd ib kem tshwj xeeb yog mob siab rau nws hauv cov lus qhia rau kev siv ntawm Insuman. Kev pheej hmoo ntawm qhov txaus ntshai poob rau hauv qab zib yog qhov tshwj xeeb tshaj yog thaum pib ntawm kev siv tshuaj insulin, thaum tus neeg mob tsuas yog kawm los laij lub koob tshuaj. Lub sijhawm no, kev saib xyuas cov kua nplaum hnyav yog qhov kev pom zoo: lub ntsuas dej siv tsis yog nyob rau yav sawv ntxov thiab ua ntej noj mov, tab sis tseem nyob nruab nrab ntawm ntu.

Hypoglycemia nres ntawm thawj cov tsos mob los yog muaj suab thaj tsawg, txawm tias nws tsis cuam tshuam rau kev nyob zoo. Cov phiajcim kev phom sij: kev poob siab, kev tshaib plab, tshee tshee, cev lossis tawv nqaij ntawm tus nplaig thiab daim di ncauj, tawm hws, palpitations, mob taub hau. Qhov kev nce ntawm hypoglycemia tuaj yeem xav tias yog kev ua kom qaug dab peg, kev tswj tsis tau tus kheej thiab kev ua haujlwm ntawm kev txav mus los. Tom qab tsis nco qab, tus mob sai sai, pib.

Yuav muaj kev mob ntshav qab zib ntau dua ib zaug, cov mob ntshav qab zib yuav hnov ​​nws cov tsos mob tshwm sim, thiab qhov ntau dua yuav tshwm sim txo cov piam thaj tom qab. Muaj ntshav ntau ntau yuav tsum tau txhaj tshuaj kom haum ntawm Insuman. Thawj pab rau cov piam thaj qis - 20 g piam thaj Cov. Cov koob tshuaj no tuaj yeem ua dhau nyob hauv qhov xwm txheej loj, txij li ib qho nyiaj ntawm cov carbohydrates yuav sai sai ua rau lub xeev rov qab - hyperglycemia.

Ib qho kev cuam tshuam ntawm kev hnyav hyperglycemia yog. Feem ntau nws tshwm sim rau ob peb hnub, yog li tus neeg mob lub sijhawm tau nqis tes ua. Hauv qee kis, txij li pib ntawm ketoacidosis mus rau coma, tsuas yog ob peb teev dhau, yog li koj yuav tsum txo cov piam thaj siab sai sai tom qab nws kuaj tau. Rau cov laj thawj no siv tsuas yog insuman yooj yim Cov. Raws li txoj cai dav dav, 1 chav nyob yuav tsum tau txo qis glycemia los ntawm 2 mmol / L. Neeg tsis ntseeg xav. Txhawm rau tiv thaiv cov ntshav qog ntshav qab zib, qab zib hauv thawj theem yog txo mus rau 8. Kev kho rau kev coj ua yog ua tom qab ob peb teev, thaum lub sijhawm dhau los ntawm kev txhaj tshuaj dhau los tau tas sij hawm.

Nco ntsoov kawm! Koj puas xav tias kev tswj hwm kev noj qab haus huv ntawm cov tshuaj thiab cov kua dej yog ib txoj kev los tswj cov piam thaj kom tswj? Tsis muaj tseeb! Koj tuaj yeem soj ntsuam qhov no koj tus kheej los ntawm kev pib siv nws.

**** HOECHST MARION ROUSSEL Aventis Pharma Deutschland GmbH Sanofi-Aventis Deutschland GmbH / Sanofi-Aventis East Hoechst Marion Russel GmbH

Tej yam kev mob tshwj xeeb

• tshuaj insulin-isophan (tib neeg kev tsim kho tshuab) 3.571 mg (100 IU) Cov tsis muaj zog: protamine sulfate - 318 μg, metacresol (m-cresol) - 1.5 mg, phenol - 600 μg, zinc chloride - 47 μg, sodium dihydrogen phosphate dihydrate - 2.1 mg, glycerol 85% - 18.824 mg, sodium hydroxide (rau kho cov pH) - 576 μg, hydrochloric acid (rau kho cov pH) - 246 μg, dej d / i - txog 1 ml. tshuaj insulin-isophan (tib neeg kev tsim kho tshuab) 3.571 mg (100 IU) Cov tsis muaj zog: protamine sulfate - 318 μg, metacresol (m-cresol) - 1.5 mg, phenol - 600 μg, zinc chloride - 47 μg, sodium dihydrogen phosphate dihydrate - 2.1 mg, glycerol 85% - 18.824 mg, sodium hydroxide (rau kho cov pH) - 576 μg, hydrochloric acid (rau kho cov pH) - 246 μg, dej d / i - txog 1 ml.

Tso tawm daim ntawv, muaj pes tsawg leeg thiab ntim khoom

Yuav Insuman Bazal GT tuaj yeem nyob rau hauv daim ntawv ntawm kev ncua rau kev txhaj tshuaj hauv qab daim tawv nqaij hauv qhov ntau npaum ntawm 100ME / ml. Txhua lub khob fwj muaj 5 ml Insuman Bazal GT thiab kaw nrog lub hau txhuas uas npog sab saum toj nrog lub hau yas rau ntxiv kev tiv thaiv. Muaj 5 fwj nyob hauv ib pob ntawv thawv. Ntxiv rau, cov tshuaj muaj nyob hauv 3 ml khob cartridge. Ntawm ib feem nws tau kaw los ntawm kev siv zog nres thiab npog nrog txhuas, thiab ntawm ob - los ntawm lub zog piston. Lub cartridge muaj 3 lub pob ntawm hlau. Tsib li ntawv nyob hauv cov thawv.

Pharmacological kev txiav txim

Cov tshuaj insulin txo qis dua ntawm cov kua nplaum, txhawb kev tsim cov khoom sib txuas tshiab thiab txo cov teebmeem catabolic. Cov tshuaj txhawb cov txav ntawm cov piam thaj los ntawm cov cell thiab synthesizes glycogen. Cov nyhuv ntawm cov lus qhia hauv qab daim tawv nqaij tshwm sim hauv ib teev, ua qhov siab tshaj plaws tom qab peb teev thiab kav ntev li ntawm 11 txog 20 teev. T1 / 2 ntsuas cua yog 5 feeb, thiab nyob rau hauv qhov chaw lub raum tsis ua haujlwm, nws nce ntau.

Insuman Bazal GT yog siv rau cov ntshav qab zib, uas yuav tsum tau qhia txog cov tshuaj insulin ntxiv.

Noj ntau dhau

Kev noj tshuaj ntau dhau, piv txwv li, kev qhia txog kev noj tshuaj ntau dhau nyob rau hauv kev sib piv nrog cov zaub mov lossis lub zog noj, tuaj yeem ua rau muaj kev mob ntshav qab zib ntau ntau, uas tuaj yeem tsim kev hem thawj, txawm tias tuag. Txog kev kho mob ntawm cov mob ntshav qab zib ntawm qhov tsis yooj yim me me, thaum tus neeg mob tswj hwm kom meej meej, nres los ntawm kev siv khoom noj khoom haus carbohydrate. Koj yuav tsum tau hloov kho qhov koob tshuaj, hloov cov cai thiab kev noj zaub mov ntau npaum li cas thiab kho qhov kev ua si hauv kev ua kis las. Ntau qhov xwm txheej ntawm cov ntshav qog nqaij ntshav siab, uas tuaj yeem ua ke nrog comotose lub xeev, mob nqaij ntshiv lossis mob tsis zoo hauv cov leeg hlwb, tuaj yeem nres los ntawm cov thawj coj ntawm glucagon intramuscularly lossis subcutaneously, los yog kev qhia ntawm lub siab concentration dextrose daws teeb meem los ntawm cov leeg ntshav. Rau cov menyuam yaus, kev txiav txim siab ntawm lub koob tshuaj dextrose yog nce raws lawv lub cev qhov hnyav. Thaum cov piam thaj hauv siab sawv siab, nws yuav tsum tau noj zaub mov carbohydrate thiab tswj hwm tus kws kho mob uas tuaj koom, vim tias tom qab pib kho cov tsos mob ntawm cov ntshav qab zib hauv lub cev, nws tuaj yeem rov mob ntxiv. Thaum kho cov menyuam yaus, nws yog ib qho tseem ceeb los ua tib zoo saib xyuas cov piam thaj hauv qab, vim nws yuav tshwm sim muaj qhov cuam tshuam loj heev ntawm kev tshaib plab lub zog yuav tshwm sim. Thaum muaj mob ntshav qab zib ntev ntev tom qab siv cov glucagon los yog dextrose, nws yog ib qho tsim nyog yuav tsum tso ib lub dauv nrog qhov siab ntawm dextrose kev daws teeb meem kom tsis txhob muaj mob ntawm kev txhim kho ntawm lub zog qias neeg dua. Ntxiv rau, nws tsim nyog txiav txim siab tias qee qhov xwm txheej yuav xav tau kev thauj mus los ntawm ib tus neeg mus rau chav saib xyuas kev mob hnyav rau kev tswj hwm nws tus mob thiab tswj hwm txhua qhov kev ntsuas kho mob.

Yeeb tshuaj sib cuam tshuam

Kev sib cuam tshuam ntawm Insuman Bazal GT nrog lwm cov tshuaj tuaj yeem saib zoo li no: 1. Nrog rau beta-blockers, clonidine, lithium ntsev - qhov txo qis hauv cov nyhuv hypoglycemic ntawm cov tshuaj. 2. Nrog ethanol - ib qho kev txo qis hauv cov nyhuv hypoglycemic ntawm cov tshuaj, kev nce ntxiv hauv kev pheej hmoo ntawm kev tsim lub zog qias neeg, thiab txo cov piam thaj hauv qab mus rau ib qho txiaj ntsig uas cuam tshuam rau kev noj qab haus huv thiab lub neej. 3. Nrog pentamidine - qhov kev pheej hmoo ntawm kev tsim lub zog ntawm kev tshaib plab, uas tuaj yeem mus rau hauv hyperglycemia. 4. Nrog cov tshuaj sympatholytic - txo qis lossis ua tiav kev tshem tawm cov tsos mob ntawm cov kab mob ntawm lub hlwb tsis zoo.

Cev xeeb tub thiab lactation

Thaum cev xeeb tub, nws yog ib qho tseem ceeb uas yuav tau noj Insuman Bazal GT. Nws tsim nyog hais tias cov tshuaj insulin tsis muaj peev xwm nkag mus rau qhov tso ntawm thaj chaw me. Nws yog ib qho tseem ceeb kom ua tiav cov kev tswj xyuas metabolic thoob plaws lub sijhawm cev xeeb tub rau cov neeg uas mob ntshav qab zib mellitus tau kuaj pom ua ntej cev xeeb tub, thiab cov neeg uas mob ntshav qab zib mellitus pib tshwm sim thaum cev xeeb tub. Hauv thawj peb lub hlis, xav tau cov tshuaj insulin yuav tsawg zuj zus, tab sis muaj insulin ntau ntxiv hauv zaum ob thiab thib peb. Tom qab yug menyuam tas, xav tau cov tshuaj insulin sai sai, uas ua rau muaj kev pheej hmoo ntawm kev tsim lub zog sai sai. Kev saib xyuas cov kua nplaum kom zoo yuav tsum muaj thaum cev xeeb tub thiab tom qab yug menyuam tas. Thaum npaj kev cev xeeb tub thiab thaum nws tshwm sim, nws yog ib qho tseem ceeb qhia rau tus kws kho mob uas koom nrog txog qhov no. Ua ntej koj pib npaj, koj yuav tsum sab laj nrog koj tus kws kho mob thiab nrhiav kom paub txhua yam ntawm kev yuav ua li cas npaj rau cev xeeb tub, thiab ntawm thawj cov cim qhia ntawm nws. Nws yog ib qho tseem ceeb kom nco ntsoov tias thaum lub sij hawm pub mis niam tsis muaj contraindications rau kev siv cov tshuaj insulin, tab sis ua tib zoo xav txog kev kho ob qho tshuaj insulin thiab kev noj haus.

Cia rau cov neeg mob

• cia rau hauv qhov chaw qhuav
• Khaws rau hauv qhov txias (t 2 - 5)
• txav deb ntawm menyuam yaus
• muab cia rau hauv qhov chaw tsaus

• Biogulin Daim Kab Xev U40, Isofan Insulin Ntiaj Teb Khob, Levulin L, Levulin N, Monotard, Humulin L, Humulin N

Nruab nrab ntev tib neeg lub insulin

Cov Tshuaj Pharmacokinetics

Hauv cov tib neeg muaj kev noj qab haus huv, T 1/2 ntawm ntshav ntshav insulin yog kwv yees li 4-6 feeb. Hauv cov neeg mob uas mob raum tsis zoo, ntev dua. Txawm li cas los xij, nws yuav tsum raug sau tseg tias pharmacokinetics ntawm insulin tsis cuam tshuam nws cov nyhuv metabolic.

Kev Qhia Txog Insuman ® Bazal GT

Mob ntshav qab zib mellitus xav tau kev kho mob insulin.

Kho thaj chaw

Cov nyhuv hypoglycemic ntawm Insuman Bazal tau tiav vim yog nws cov khoom xyaw - insulin-isophan. Cov tshuaj hauv nws cov qauv thiab cov yam ntxwv zoo ib yam li cov tshuaj hormones tsim hauv tib neeg lub cev. Nws tau los ntawm kev tshuaj ntsuam genetic engineering.

Cov tshuaj muaj nyob rau hauv pab pawg ntawm cov tshuaj ntawm nruab nrab lub sijhawm ntawm kev ua. Tom qab kev tswj hwm, subcutaneously khi rau qee qhov tau txais ntawm daim nyias nyias ntawm lub xovtooj ntawm, tsim txoj haujlwm tshwj xeeb uas ua rau cov txheej txheem txuas ntxiv mus. Nws txo cov piam thaj los ntawm kev nrawm rau nws txoj kev thauj mus los, txhim kho kev nqus, inhibiting qhov kev tsim ntawm lub siab, thiab ua kom cov txheej txheem metabolic nrog nws koom nrog.

Lub sijhawm ntawm cov nyhuv exerted los ntawm cov tshuaj yog nyob ntawm qhov ceev uas cov tshuaj insulin tau nqus rau hauv lub cev, qhov koob tshuaj, thaj chaw txhaj tshuaj, thiab cov kab ke ntawm kev tswj hwm. Yog li, cov insulin ua tshwj xeeb tsis yog hauv cov neeg mob ntshav qab zib sib txawv, tab sis txawm nyob hauv ib tus neeg mob.

Cov nqi isofan nruab nrab: qhov pib ntawm kev ua - ib thiab ib nrab xuaj moos tom qab txhaj tshuaj, cov nyhuv siab tshaj plaws ua rau pom lub sijhawm 4-12 teev, lub sijhawm ntawm hypoglycemic kev txiav txim siab - txog li 1 hnub.

Cov tshuaj tau muab faib thoob cov nqaij hauv ntau qhov sib txawv, tsis tuaj yeem hla mus rau hauv cov mis thiab dhau ntawm qhov tso me nyuam. Nws siv nyob rau hauv ib qho tseem ceeb hauv daim siab thiab lub raum. Nws tawm hauv cov zis.

Hla kev sib txuam yeeb tshuaj

Thaum lub caij cov tshuaj insulin, Insuman Bazal GT yuav tsum tau yug los rau hauv lub siab tias thaum ua ke nrog qee cov tshuaj, kev hloov pauv hauv hypoglycemic effect lossis kev cuam tshuam ntawm cov kev kho mob ntawm lwm cov tshuaj muaj peev xwm ua tau:

• Insuman's hypoglycemic effect tau txhim kho thiab ua kom ntev dua thaum ua ke nrog cov tshuaj qab zib qhov ncauj, ACE inhibitors, iMAO, Disoprimide, salicylates, anabolics, tshuaj nrog txiv neej cov tshuaj hormones, Fluoxetine, Fenfluramine, Ifosfamide, sulfonamides, Amphetamine thiab tetetamine.
• Kev sib xyaw nrog GCS, tshuaj diuretic, corticotropin, Danazole, glucagon, cov tshuaj hormones (estrogens, gestagens), sympathomimetics, cov thyroid tshuaj, phenothiazine derivatives, barbiturates thiab qee yam tshuaj txo cov nyhuv hypoglycemic ntawm insulin.
• Thaum muab tso ua ke nrog BAB, Clonidine, ntsev ntsev lithium, qhov kev txiav txim ntawm Insuman Bazal tsis yooj yim sua twv: qhov hypo- lossis hyperglycemic effect yuav tshwm sim.
• Ethanol ua raws li kev npaj insulin kuj tsis tau ceeb toom: qhov tshwm sim ntawm Insuman yuav nce ntxiv lossis poob qis. Nws yuav tsum tau yug los hauv lub siab tias yog tias tus neeg mob lub ntsej muag glycemia qis qis, tom qab ntawd qaug cawv lossis haus cawv, nws qib yuav poob mus rau ib qho tseem ceeb, uas tuaj yeem ua kev hem thawj rau kev noj qab haus huv thiab lub neej muaj ntshav qab zib.

Sab sij huam

Thaum lub sijhawm siv cov tshuaj, nws yog ib qho tsim nyog yuav tsum coj mus rau hauv tus account tias insulin Bazal muaj peev xwm ua rau muaj kev tsis txaus siab nyob rau hauv cov neeg mob ntshav qab zib.

Feem ntau cov kev mob tshwm sim nrog kev kho mob insulin. Nws tshwm sim thaum cov koob tshuaj tau siv uas muaj ntau zaus siab dua qhov xav tau ntawm lub cev. Rov ua dua qhov mob hnyav ntawm cov piam thaj hauv lub cev ua rau kev txhim kho cov leeg hlwb tsis zoo, uas tuaj yeem nrog tus mob nrhav, tsis nco qab. Cov kev tawm tsam ntev thiab mob hnyav tuaj yeem ua rau tus neeg mob tuag.

Yog tias qhov txo qis hauv cov piam thaj hauv lub ntsej muag tau tshwm sim ntau, qhov no tuaj yeem ua rau hypokalemia nrog cov teeb meem ntawm CVS thiab / lossis mob hlwb.

Ntxiv rau cov ntshav qog ntshav qab zib, cov ntshav qab zib kuj tseem muaj lwm qhov tsis xav ua, ua qauv tsis ua haujlwm ntawm lub hauv nruab nrog cev thiab cov kab ke:

• Txoj kev ua xua ntawm kev ua xua: anaphylaxis, kev tawm tsam ntawm daim tawv nqaij dav dav, Quincke's edema, bronchospasm, kev tsim cov tshuaj tiv thaiv (kev kho lub cev ntawm cov tshuaj insulin kuj yuav tsum tau).
• CCC: tso ntshav siab.
• Cov txheej txheem kev zom zaub mov: edema, tshaj sodium hauv lub cev.
• Organs ntawm lub zeem muag: rov qab pom lub qhov muag tsis pom kev, lub sijhawm luv luv tsis zoo ntawm retinopathy, kev puas tsuaj rau lub qhov muag lossis lub qhov nrawm retina, tom qab los ntawm kev dig muag ib ntus lossis mus tas li.
• Cov tawv nqaij thiab cov nqaij mos subcutaneous: lipodystrophy (nrog kev txhaj tshuaj tas li nyob rau hauv ib qho chaw), vim li ntawd - kev nqus ntawm cov tshuaj insulin.
• Lwm qhov kev tsis txaus siab: liab liab ntawm qhov chaw txhaj tshuaj, khaus, mob, urticaria, o lossis o, o.