Cov tshuaj Abipim: cov lus qhia rau kev siv

Tshuaj Abipim siv rau cov neeg laus uas muaj cov kab mob no: kev kis mob los ntawm microflora rhiab rau cov tshuaj: mob ntsws ua pa, nrog rau mob ntsws, mob ntsws, mob ntawm daim tawv nqaij thiab cov nqaij mos subcutaneous, mob intraabdominal, suav nrog rau kev mob peritonitis thiab mob biliary, mob gynecological, septicemia, empirical kev kho mob ntawm cov neeg mob uas mob neutropenic, tiv thaiv kev mob tom qab ntawm kev phais mob plab.
Tshuaj Abipim nws yog siv los kho cov kab mob no hauv cov menyuam yaus: mob ntsws, mob txeeb zig, nrog rau pyelonephritis, kis mob ntawm daim tawv nqaij thiab cov nqaij mos subcutaneous, mob septicemia, kev kho mob ntawm cov neeg mob neutropenic ua npaws, cov kab mob rau daim tawv nqaij.

Txoj kev ntawm daim ntawv thov

Kuaj Mob Ntau Zaus Abipim yog 1 g, uas tau muab tshuaj rau ib leeg lossis intramuscularly nrog qhov luv ntawm 12:00. Lub sijhawm ib txwm kho yog 7-10 hnub, kev kis tus kab mob hnyav yuav tau kho ntev dua.
Txawm li cas los xij, qhov ntau npaum li cas thiab txoj kev ntawm cov thawj coj sib txawv raws li kev nkag siab ntawm cov pathogens, qhov mob hnyav, thiab lub xeev kev ua haujlwm ntawm tus neeg mob lub raum.
Thaum siv lub hauocaine tov rau cov tshuaj intramuscular ua cov kuab tshuaj, nws yuav tsum ua tib zoo xav txog kev nyab xeeb cov ntaub ntawv ntawm lidocaine thiab ua rau kev sim tawv nqaij rau qhov nws nkag siab.
Cov kab mob txeeb zig ntawm mob me txog rau mob hnyav - 500 mg - 1 g tso ntshav lossis tso ntshav txhua 12:00.
Lwm qhov mob sib khuav mus rau mob nyhav 1 g txhaj tshuaj rau lub cev lossis tso ntshav txhua 12:00.
Kev kis mob hnyav 2 g txhua 12:00.
Muaj mob hnyav heev thiab ua rau tuag tau ntawm 2 g txhua 8:00.
Txog rau kev tiv thaiv tus kab mob thaum lub sijhawm phais. 60 feeb ua ntej pib kev phais mob, cov neeg laus tau muab 2 g ntawm tshuaj rau 30 feeb. Thaum xaus, ib qho tshuaj ntxiv 500 mg ntawm metronidazole yog muab tshuaj rau leeg. Metronidazole cov kev daws teeb meem yuav tsum tsis txhob muab rau ib leeg nrog cefepime. Txoj kev lis ntshav yuav tsum yaug ua ntej ua cov tshuaj metronidazole.
Lub sijhawm ua haujlwm ntev (ntau dua 12:00) kev phais mob thaum 12:00 teev tom qab thawj koob tshuaj, kev rov ua dua ntawm cov tshuaj sib npaug ntawm cov tshuaj tau pom zoo, tom qab kev qhia ntawm metronidazole.
Cov menyuam hnub nyoog 1 txog 2 hlis. Cov tshuaj raug txwv tsuas yog siv rau kev noj qab haus huv 30 mg / kg lub cev hnyav txhua 12 lossis 8:00, nyob ntawm qhov mob hnyav sib kis.
Cov menyuam yaus los ntawm 2 lub hlis. Qhov siab tshaj rau cov menyuam yuav tsum tsis pub tshaj qhov koob tshuaj pom zoo rau cov neeg laus. Cov koob tshuaj pom zoo rau cov menyuam yaus lub cev nyhav txog 40 kg yog qhov nyuaj lossis tsis mob tso zis mob (nrog rau pyelonephritis), mob tsis yooj yim rau daim tawv nqaij, mob ntsws, thiab zoo li muaj kev kho mob febrile neutropenia yog 50 mg / kg txhua 12:00 (rau cov neeg mob febrile neutropenia thiab mob rau cov leeg mob - txhua 8:00). Lub sijhawm ib txwm kho yog 7-10 hnub, kev kis tus kab mob hnyav yuav tau kho ntev dua.
Rau cov menyuam yaus lub cev nyhav 40 kg lossis ntau dua, cov koob tshuaj tau sau tseg ua tus laus.
Cov qhia ntawm cov tshuaj. Cov tshuaj tuaj yeem raug txhaj tshuaj rau hauv qhov quav lossis sib sib zog nqus txhaj tshuaj rau hauv cov leeg nqaij loj (piv txwv, nyob rau sab saud sab nrauv ntawm cov gluteus maximus gluteus leeg).
Taw qhia Kev mob siab rau txoj kev tswj hwm tau zoo dua rau cov neeg mob uas muaj kab mob hnyav lossis ua rau muaj sia.
Nrog txoj kev ncaj ncees ntawm txoj kev tswj hwm, noj zaub mov yaj yog yaj hauv dej tsis huv rau kev txhaj tshuaj, hauv 5% kua nplaum ua rau kev txhaj tshuaj lossis 0.9% sodium chloride tov, raws li qhia hauv qab no. Nws muab tshuaj rau cov tshuaj maj mam qeeb rau 3-5 feeb lossis ntawm kev tso dej noo.
M taw qhia. Cov tshuaj yog yaj hauv dej tsis huv rau kev txhaj tshuaj, 0.9% sodium chloride tov rau kev txhaj tshuaj, 5% kua nplaum tov rau kev txhaj tshuaj, cov dej bacteriostatic rau txhaj nrog paraben lossis benzyl cawv, 0.5% lossis 1% daws ntawm lidocaine hydrochloride.

Sab sij huam

Los ntawm cov tshuaj tiv thaiv kab mob: kev tiv thaiv tsis haum, suav nrog anaphylaxis, anaphylactic shock, angioedema.
Los ntawm cov txheej txheem ua pa: hnoos, mob caj pas, ua pa luv.
Los ntawm cov hlab plawv: tachycardia.
Los ntawm cov kav dej alimentary: xeev siab, ntuav, dyspepsia, candidiasis ntawm lub qhov ncauj ntawm lub qhov ncauj, hloov pauv ntawm saj, raws plab, colitis (suav nrog pseudomembranous).
Los ntawm cov leeg hlwb: mob taub hau, pw tsaug zog, ntxhov siab, mob plab.
Los ntawm lub plab zom mov: kab mob siab, mob cholestatic daj ntseg.
Ntawm ib feem ntawm daim tawv nqaij thiab cov nqaij mos subcutaneous: pob khaus, khaus, urticaria.
Lwm yam: asthenia, tawm hws, kub cev, vaginitis, erythema, mob hauv siab, mob nraub qaum, mob caj dab.
Los ntawm tus txheej txheem ua pa: kev ua pa nyuaj.
Los ntawm cov hnyuv hauv plab: mob plab, cem quav.
Los ntawm lub paj hlwb: kiv taub hau, pliaj.
Los ntawm cov hlab plawv system: vasodilation.
Lwm tus: khaus ntawm chaw mos, ua npaws, thiab mob plab hlaub.
Los ntawm lub cev tiv thaiv kab mob: anaphylaxis.
Los ntawm lub paj hlwb: tiv thaiv mob hlwb.
Cov tshuaj tiv thaiv hauv zos ntawm qhov chaw txhaj tshuaj: nrog cov leeg - phlebitis thiab o, nrog i / m - mob, o.

Kev cuam tshuam nrog lwm yam tshuaj

Nephrotoxicity tau pom tom qab tib lub sijhawm siv ntawm lwm cov cephalosporins nrog furosemide diuretics.
Cepepime nrog cov ntsiab lus ntawm 1 txog 40 mg / ml yog sib xws nrog cov kev daws teeb meem zoo li no: 0.9% sodium chloride tov rau kev txhaj tshuaj, 5 thiab 10% kua qabzib rau kev txhaj tshuaj, 6M sodium lactate tov rau kev txhaj tshuaj, 5% kua nplaum tov thiab 0.9% sodium tshuaj dawb rau kev txhaj tshuaj, Lub suab tawm kev daws teeb meem nrog lactate thiab 5% piam thaj rau kev txhaj tshuaj.
Txhawm rau kom tsis txhob muaj kev cuam tshuam yeeb tshuaj nrog lwm cov tshuaj, cov kev daws teeb meem (zoo li feem ntau lwm yam tshuaj tua kab mob act-lactam) tsis yog siv ua ke nrog kev daws cov tshuaj metronidazole, vancomycin, gentamicin, tobramycin sulfate thiab netromycin sulfate. Yog tias tsim nyog, kev teem sij hawm noj mov nrog cov tshuaj no, txhua yam tshuaj tua kab mob tau muab cais nyias.
Ua rau ntawm kev kuaj pom.
Kev siv cov cij taum pauv tuaj yeem ua rau muaj qhov tsis zoo los ntawm kev tsis txaus siab rau cov ntshav qabzib nyob rau hauv cov zis thaum siv Benedict reagent. Nws raug nquahu kom siv cov kev ntsuas ntshav qab zib raws li cov tshuaj tiv thaiv enzymatic ntawm qabzib oxidation.

Noj ntau dhau

Cov tsos mob ntawm kev siv tshuaj ntau dhau Abipim: Nyob rau hauv cov kis mob ntawm qhov tseem ceeb tshaj ntawm cov koob tshuaj pom zoo, tshwj xeeb tshaj yog nyob rau hauv cov neeg mob uas tsis hnov ​​mob raum lub raum, cov kev mob tshwm sim yog nthuav dav. Cov tsos mob ntau dhau muaj xws li encephalopathy, nrog ua kom hnov ​​lus, hnov ​​qab tsis meej pem, tsis hnov ​​qab, tsis nco qab, tsis nco qab, myoclonia, kev tawm tsam epileptiform, kev tsis txaus siab neuromuscular.
Kev Kho Mob. Nws yog ib qho tsim nyog yuav tsum txwv qhov kev qhia ntawm cov tshuaj, nqa tawm kev kho mob. Kev siv hemodialysis nrawm nrawm ntawm kev tshem tawm ntawm cefepime ntawm lub cev, peritoneal dialysis tsis muaj txiaj ntsig. Kev tsis haum tshuaj loj ntawm hom tam sim ntawv xav tau kev siv adrenaline thiab lwm yam kev tu xyuas hnyav.

Cov lus qhia rau kev siv Abipim

cov tshuaj nquag: sefepime,

1 lub vial muaj cov npluag roj 500 mg lossis 1000 mg (raws li cov tshuaj ua kom tsis haum ntawm cefepime hydrochloride thiab L-arginine).

Cov kab mob kis los ntawm microflora rhiab rau cov tshuaj: kab mob ua pa, nrog rau mob ntsws, mob ntsws, mob rau ntawm daim tawv nqaij thiab cov nqaij mos subcutaneous, mob rau hauv lub cev, nrog rau mob peritonitis thiab mob biliary, mob gynecological, septicemia.

Kev kho qhov tseeb ntawm cov neeg mob uas kub taub hau neutropenic.

Kev tiv thaiv ntawm kev mob tom qab ntawm kev phais mob plab.

Cov menyuam yaus: mob ntsws, mob txeeb zig, nrog rau pyelonephritis, kis mob ntawm daim tawv nqaij thiab cov nqaij mos subcutaneous, septicemia, kev kho kom ncaj ncees rau cov neeg mob neutropenic fever, kab mob meningitis.

Sab sij huam

Los ntawm cov tshuaj tiv thaiv kab mob: kev tiv thaiv tsis haum, suav nrog anaphylaxis, anaphylactic shock, angioedema.

Los ntawm cov txheej txheem ua pa: hnoos, mob caj pas, ua pa luv.

Los ntawm cov hlab plawv: tachycardia.

Los ntawm cov kav dej alimentary: xeev siab, ntuav, dyspepsia, candidiasis ntawm lub qhov ncauj ntawm lub qhov ncauj, hloov pauv ntawm saj, raws plab, colitis (suav nrog pseudomembranous).

Los ntawm cov leeg hlwb: mob taub hau, pw tsaug zog, ntxhov siab, mob plab.

Los ntawm lub plab zom mov: kab mob siab, mob cholestatic daj ntseg.

Ntawm ib feem ntawm daim tawv nqaij thiab cov nqaij mos subcutaneous: pob khaus, khaus, urticaria.

Lwm yam: asthenia, tawm hws, kub cev, vaginitis, erythema, mob hauv siab, mob nraub qaum, mob caj dab.

Los ntawm tus txheej txheem ua pa: kev ua pa nyuaj.

Los ntawm cov hnyuv hauv plab: mob plab, cem quav.

Los ntawm lub paj hlwb: kiv taub hau, pliaj.

Los ntawm cov hlab plawv system: vasodilation.

Lwm tus: khaus ntawm chaw mos, ua npaws, thiab mob plab hlaub.

Los ntawm lub cev tiv thaiv kab mob: anaphylaxis.

Los ntawm lub paj hlwb: tiv thaiv mob hlwb.

Cov tshuaj tiv thaiv hauv zos ntawm qhov chaw txhaj tshuaj: nrog cov leeg - phlebitis thiab o, nrog i / m - mob, o.

Yuav ua li cas yuav Abipim ntawm YOD.ua?

Koj puas xav tau Abipim? Hais nws txoj cai nyob ntawm no! Kev tso npe ntawm txhua yam tshuaj muaj nyob ntawm YOD.ua: koj tuaj yeem khaws cov tshuaj lossis ntawv xa tawm hauv tsev muag tshuaj ntawm koj lub nroog ntawm tus nqi uas tau hais hauv lub vev xaib. Qhov kev txiav txim yuav tos koj rau ntawm lub tsev muag tshuaj, uas koj yuav tau txais ib tsab ntawv ceebtoom ua SMS (qhov tuaj tau kev pabcuam yuav tsum tau hais meej hauv cov khw muag tshuaj).

Ntawm YOD.ua yeej ib txwm muaj ntaub ntawv hais txog qhov muaj ntau ntawm cov tshuaj hauv ntau tus nroog loj tshaj plaws ntawm Ukraine: Kiev, Dnieper, Zaporozhye, Lviv, Odessa, Kharkov thiab lwm qhov loj. Nyob hauv ib qho ntawm lawv, koj tuaj yeem ua tau yooj yim thiab yooj yim txiav txim tshuaj los ntawm YOD.ua lub vev xaib, thiab tom qab ntawd, nyob rau lub sijhawm zoo, mus tom qab lawv mus rau lub chaw muag tshuaj lossis kev xa khoom xa tuaj.

Xyuam xim: xaj thiab tau txais tshuaj, koj yuav xav tau ntawv tso cai los ntawm kws kho mob.

Cov tub ceev xwm Pharmacological

Tsefepim yog b-lactamium cephalosporinium tshuaj tua kab mob ntawm plaub tiam ntawm ntau yam rau kev pom zoo ntawm kev ua niam txiv. Kho cov kab mob kev ua kom zoo. Cov nquag muaj ntau tshaj plaws yog cov kab mob gram-zoo thiab gram-tsis zoo, suav nrog cov leeg kab mob feem ntau, cov uas mus txog aminoglycosides thiab cov tshuaj tua kab mob cephalosporin ntawm lub cim thib ob, xws li ceftazidime. Tsefepim siab pom tseeb rau b-lactamase, muaj tseeb heev hauv cov kab mob gram-tsis zoo. Cov kauj ruam ntawm cephalosporinism rau kev tso cai ntawm niam txiv ntau ntxiv ua rau muaj kev pheej hmoo thiab raug nplua RVR 3. Ntxiv rau kev ua kis las, yuav tsum muaj RVR 1a thiab 1c nrog rau kev nce qib hauv cov kab mob. Ua kom paub MBK (tsawg kawg bactericidal concentration) / МІК rau cefepіm los ua tsawg dua 2 rau tsawg dua 80% іzolyatіv uslih cov kab mob siab-zoo thiab kab mob gram-tsis zoo.

Cefepim prigny synthesis of enzymes ntawm cov kab mob klitini д ma ua ntau yam sib txawv ntawm cov kab mob gramopositive thiab gram-negative. Cephepium yog qhov ua tau zoo heev rau hydrolysis ntawm b-lactamase, kev sib tw me ntsis tau pom nyob hauv lub xub ntiag ntawm b-lactamase, uas tau sau los ntawm cov keeb kwm chromosome, thiab shvidko nkag mus hauv cov kab mob hlwb-tsis zoo.

Tsefepіm nquag schodo ntawm xws li cov kab mob me me:

Cov Qauv Ntsuas aerobi:Dab Tsi Staphylococcus aureus (suav nrog nrog shtami, los tsim b-lactamase), Staphylococcus epidermidis (suav nrog shtami, scho tsim b-lactamase), іshi shti stafіlokokіv (suav nrog S. hominis, S. saprophyticus), Cov kab mob Streptococcus pyogenes (pawg A) Tus kab mob Streptococcus agalactiae (pawg B) Kab mob ntsws dej liab (suav nrog nrog tus ntoo khaub thuas nruab nrab rau penicillin - і ntawm 0.1 txog 0.3 mcg / ml), b-hemolitic streptococci tshiab (pawg C, G, F), S. bovis (pawg D), pawg streptococci ViridansCov. (Bіlshіst straіnt enterokokіv, piv txwv li: Nkag mus rau hauv faecalis, staphylococcus, tiv taus methicillin, tiv taus tshuaj tua kab mob cephalosporin ntau dua, suav nrog cefepim),

Gram-negative aerobi:PseudomonassppCov. (suav nrog P. aeruginosa, P. putida, P. stutzeri), Escherichia coli, Klebsiella spp. (suav nrog K. pneumoniae, K. oxytoca, K. ozaenae), Enterobacter spp. (suav nrog E. cloacae, E. aerogenes, E. sakazakii), Kev ua Proteus spp. (suav nrog P. mirabilis, P. vulgaris), Acinetobacter calcoaceticus (suav nrog pidrodini Nitratus, Іwoffi), Aeromonas hydrophila, Capnocytophagaspp., CitrobactersppCov. (suav nrog C. ntau, C. freundii), Campylobacter jejuni, Gardnerella vaginalis, Haemophilus ducreyi, H. mob khaub thuas (suav nrog nrog shtami, los tsim b-lactamase), H. parainfluenzae, Hafnia alvei, Legionella spp., Morganella morganii, Moraxella catarrhalis (Branhamella) catarrhalis (suav nrog nrog shtami, los tsim b-lactamase), Neisseria gonorrhoeae (suav nrog nrog shtami, los tsim b-lactamase), N. meningitidis, Providencia spp. (suav nrog P. rettgeri, P. stuartii), Salmonella spp., Serratia (suav nrog S. marcescens, S. liquefaciens), Ntxaug Yajspp., Yersinia enterocoliticaCov. Tsefepim tsis muaj zog Xanthomonas (Pseudomonas) maltophilia,

anaerobi:Bacteroides sppCov. (suav nrog B. melaninogenicus uas іnshі mіkroorganіzmi lub qhov ncauj tsis muaj ncauj, uas belongs rau Bacteroides), Clostridium perfringens, Fusobacterium spp., Mobiluncus spp., Peptostreptococcus spp., Veillonella spp. Cefepim tsis muaj zog Bacteroides fragilis і Clostridium difficile).

Cov Tshuaj Pharmacokinetics. Tsefepіm vnostyu vmoktutsya pislya vnutrіshnyom'yazovogo qhia.

Qhov nruab nrab ntawm lub plasma cefepima hauv cov neeg laus noj qab haus huv tom qab ib leeg tso ntshav ntawm qhov quav (tso ntshav) tso ntshav ntawm cov kab noj mov.

Qhov nruab nrab nruab nrab ntawm cefepime hauv ntshav (/g / ml):

Kho cov tshuaj muaj zog ntawm cefepima ncav cuag rau pem hauv ntej, tom qab, peritoneal retinitis, hnoos qeev ua pa ntawm lub plab bronchial, hnoos qeev, prostate, appendix thiab masturbation.

Lub sijhawm ntawm cov thawj coj ntawm cefepime mus rau lub koom haum yuav tsum nyob ze rau 2 xyoo thiab tsis txhob cia pw hauv koob tshuaj ntawm 250 mg thiab 2 g. Ntawm koob tshuaj kom txog li 2 g, sab hauv nrog kev ncua sij hawm ntawm 8 xyoo nrog lub sijhawm ntev txog 9 hnub, qhov txiaj ntsig ntawm cov tshuaj yuav tsum tsis ploj.

Cepepime metabolized rau N-methylpyrrolidine, thiab nws yog sai metabolized rau N-methylpyrolidine oxide. Cefepim tuaj yeem pom cov qib siab, glomerular flirtation lub kaus mom (lub npe nrov cefrance yuav tsum ua kwv yees li 120 ml / hv, qhov nruab nrab nirkovy tshem tawm yog 110 ml / hv). Kwv yees li 80 - 85% ntawm kev noj zaub mov cefepime, 1% ntawm N-methylpyrolidine, kwv yees li 6.8% ntawm N-methylpyrolidine oxide, thiab li ntawm 2.5% noj zaub mov noj yog kwv yees li 70% ntawm koob tshuaj. Zv'yazuvannya cefepіmu nrog cov ntshav muaj protein tsawg los ua tsawg dua 19% thiab kom tsis txhob dag hauv cov tshuaj hauv cov ntshav.

Peb hais tias peb muaj hnub nyoog laus dua 65 xyoos nrog qhov ua haujlwm ntawm nirok tsis ua kom noj tshuaj ib zaug.

Yog tias muaj mob vim tsis muaj lub neej zoo, lub sijhawm lub sijhawm yog tib yam li qhov yuav tsum tau txhim kho, thaum lub laj thawj tseem ceeb vim tias tsis muaj lub txaj txaj, nws yog cov tshuaj txo qis qis dua thiab tus creatine ntawd. Lub sijhawm muaj mob nyob rau hauv kev mob nkeeg los ntawm kev ua haujlwm tsis zoo ntawm qhov hnoos qeev, xav kom nws yuav tsum tau txhaj tshuaj hemodialysis, dhau los 13 xyoo, thiab nrog kev kho mob tsis tseem ceeb ntawm kev tiv thaiv kev lim ntshav - 19 xyoo. Hauv kev mob nrog rau lub cev tsis zoo ua haujlwm, qhov koob tshuaj yuav tsum ua kom tsis pom tseeb.

Pharmacokinetics cefepіmu hauv kev mob hlwb disz cuam tshuam kev ua haujlwm ntawm daim siab, tab sis cystic fibrosis tsis yog cim. Corriguvanny dozi rau cov mob ailments tsis tsim nyog.

Cov menyuamCov. Lub chaw muag tshuaj yav dhau los ntawm zaub mov noj nqaij tau ua rau nruab nrab ob lub lis piam txog 11 hlis tom qab kev tswj hwm ib zaug, tab sis lub Kaum Ob Hlis 8 xyoo (n = 29) thiab tawv nqaij 12 xyoo (n = 13). Tom qab ua ib-sijhawm nyob sab hauv ’'' 'tau hais txog lub tsev kho mob nyob rau hauv lub chaw kho mob (kg).60.4 (30.4)% ntawm tag nrho cov tshuaj txhaj nkag tau pom meej rau lub sijhawm thib ib nrab xyoo, thiab qhov nruab nrab ntawm kev tshem tawm nickel tau dhau los ua 2.0 (1.1) ml / hv / kg. Ік і dhau los ua tus neeg mob (25 tus tub hluas thiab 17 tus ntxhais) ib hnub tsis tas yuav ntxiv rau sab nraud tshuaj thiab cov khoom nruab nrog tso cov tshuaj kho rau urachuvannyam kho rau cov tawv nqaij loj. Lub sijhawm ntawm kev tswj hwm, qhov koob tshuaj ntawm cov zaub mov noj yog 50 mg / kg ntawm daim tawv nqaij 12 xyoo (n = 13), cov tshuaj tsis raug ntxiv; lub sijhawm ntawd, qhov siab tshaj plaws nyob rau hauv ntshav tau pom; 50 mg / kg daim tawv nqaij 8 xyoo raws sijhawm. Kev tawm ntawm cefepima hauv cov menyuam yaus tom qab kev saib xyuas sab hauv ib koob ntawm 50 mg / kg yog qhov yuav tsum tau ua ntej tau txhaj tshuaj ua ntej muaj 2 g. Tom qab kev tswj hwm sab hauv, qhov siab tshaj plaws yog 0.7 ml Cov. Tom qab 8 xyoo tom qab kev tswj hwm ntawm tus nplaig, qhov ntsiab lus ntawm cov zaub mov nqaij hauv plasma thiab hauv nruab nrab tau los ua 6 μg / ml. Kev tsis txaus ntseeg txog qhov kev ntseeg ntawm lub ntsiab cai ntawm sab hauv thiab cheeb tsam kev sib xyaw ua tiav tau 82% ntawm qhov nruab nrab.

Los ntawm kev ua tsis tau ntawm kev ua qhov txheeb xyuas qhov tseeb ntawm qhov chaw ntawm tus kab mob, nws yog qhov ua tau kom nkag siab zoo rau cov tshuaj tua kab mob, tab sis tom qab sib yuav, ib teev tuaj yeem kho tau thiab cov kev kho mob muaj peev xwm nrhiav tau, thiab qhov ntau ntawm txoj kev siv tshuaj tua kab mob siv tau. Thaum muaj mob thiab muaj kabmob, kev siv tshuaj tiv thaiv tsis zoo-anaerobic thiab cov cim yuav tuaj yeem kho los ntawm Cefepim ua ke nrog cov tshuaj los tiv thaiv aerobic.

Klіnіchnі cov yam ntxwv

Kis tau tus mob, vim rhiab heev rau cov tshuaj mikroflora:

- gнфекції dichalnyh vauv, ntxiv rau mob ntsws, mob ntsws,

- cov ntaub ntawv shkіri thiab pidshkіrno klіtkovini,

- Kev mob khees-xaws rau sab hauv thiab mob, nrog rau mob rau mob peritonitis thiab kis kab mob,

Kev kho mob Empiric эvorich iz iz neutropenichnoy garyachkoy.

Kev tiv thaiv kev ua haujlwm thaum muaj xwm txheej ceev nyob hauv lub tsev noj qab haus huv sab hauv.

- gнфекції secchivividnyh nraug vauv, ntxiv rau pyonephritis,

- cov ntaub ntawv shkіri thiab pidshkіrno klіtkovini,

- txoj kev kho kom ncaj ncees ориvorich iz ot neutropenichesky hotachka,

Vz зmodiya nrog іnshimi lіkarskimi taboos uas іnshі pom

Zastosovuchi siab ntawm aminoglycoside tam sim ntawd nrog cefepime, xav tau los saib zoo rau kev ua haujlwm ntawm cov xaum xim los ntawm kev muaj peev xwm ntawm nephrotoxicity thiab ototoxicity ntawm aminoglycoside tshuaj tua kab mob. Nephrotoxicity tau qhia rau tib lub sijhawm stasis ntawm cephalosporins nrog diuretics, xws li furosemide.

Cefepim concentration ntawm 1 txog 40 mg / ml tag nrho nrog rau cov koob tshuaj zoo li no: 0.9% ntawm sodium chloride chloride rau inoculation, 5% ntawm 10% piam thaj tov rau inoculation, 6% sodium glucose faib rau 5%, 5% piam thaj thiab 0.9% sodium chloride rau inoculation, Ringer's test rau lactate thiab 5% piam thaj rau kev tiv thaiv kab mob.

Koj tuaj yeem siv tsis tau tam sim ntawv txhaj tshuaj metronidazole, vancomycin sulfate, gentamicin sulfate, thiab lwm yam thiaj li yuav nqus tau cov tshuaj uas zoo tshaj plaws, los tiv thaiv kom tsis txhob muaj cov kab mob cephalic (vim los ntawm cov tshuaj tiv thaiv β-lactam ntau ntxiv). Thaum lub sijhawm yuav tsum tau teem caij noj mov nrog zaub mov raws li kev npaj cov tawv nqaij, tshuaj tua kab mob yuav tsum tau noj tshuaj okremo.

Txaus siab rau cov txiaj ntsig ntawm kev kuaj sim.

Qhov tshwm sim ntawm kev noj zaub mov tawv nqaij tuaj yeem ua rau hibnopositive cov tshuaj tiv thaiv ntshav qab zib nyob rau hauv ib zaug ntawm Benedict's reagent. Nws pom zoo kom ntsuam xyuas cov piam thaj, raws li cov tshuaj tiv thaiv enzymatic ntawm qabzib oxidation.

Nta zastosuvannya

Thaum patsієntіv ntawm lub tuam tsev rizikom loj іnfektsіy (napriklad ntawm patsієntіv, SSMSC mayutsya nyob rau hauv anamnezі transplantatsіyu kіstkovogo mozk ntawm znizhenіy Yogo aktivnostі scho vіdbuvaєtsya rau tlі zloyakіsnoї gemolіtichnoї patologії ntawm lub ntxa progresuyuchoyu neytropenієyu) monoterapіya Mauger buti nedostatnoyu, uas qhia tau hais tias ib tug multifilament antimіkrobna terapіya.

Nws yog qhov tsim nyog yuav tsum tau txheeb xyuas cov neeg uas tau tshwm sim thaum ntxov los ntawm kev tsis txaus siab ntawm hom tsis muaj kev tiv thaiv ntawm hypertrophy ntawm cefepime, cephalosporini, penicillin, lossis beta-lactam tshuaj tua kab mob. Tshuaj tua kab mob varto ua kev zoo siab nrog kev saib xyuas peb txhua tus qhuas iz txhua hom kev fab tshuaj, tshwj xeeb tshaj yog npaj tshuaj. Thaum muaj kev fab tshuaj, cov tshuaj yuav tsum tau kho. Cov kev tsis haum loj ntawm cov tsis muaj hom ntawm hyperpathy tuaj yeem ua rau adrenaline thiab qis dua kev kho mob.

Thaum raug mob stasis, kev siv tshuaj tua kab mob ntau yam ntawm tus kabmob pseudomembranous yog yuav luag sib txawv. Nws yog ib qho tseem ceeb uas koj yuav tsum tau saib xyuas kom txhim kho cov kab mob pathology ntawm Vicenna raws plab pid teev. Daim qauv yooj yim tuaj yeem txo tau tom qab siv cov tshuaj, tab sis yog tias nws nyuaj, muaj peev xwm noj tau cov tshuaj tshwj xeeb.

Nrog kev tiv thaiv ntawm tus neeg mob txoj hauv kev thiab kab mob ntawm cov nyom, tshwj xeeb suav.

Yog tias koj muaj teeb meem nrog tshuaj tua kab mob, koj tuaj yeem npaj cov tshuaj kom npaj txhij rau kev saib xyuas lub luag haujlwm, thiab yog tias koj xav tau nkag rau hauv, koj yuav tsum nkag mus hauv. Koj yuav tsum muaj kev lom zem 60 ml / hv) ib ntog ntawm cefepіm sіd vіdkoriguvati, thiaj li them rau qhov ua siab zoo ntawm cov tshuaj. Los ntawm kev saib xyuas cov tshuaj tua kab mob ntev hauv cov menyuam yaus, cov niam tuaj yeem ntsib nrog cov koob tshuaj zoo hauv cov neeg mob uas muaj qhov tsis txaus, vim tias tsis muaj chaw pw ntxiv, yog li xav tau sijhawm ntau ntxiv. Cov qib ntawm kev ua tsis taus, qhov hnyav ntawm kev kis kab mob thiab kev muaj peev xwm ua kom tawm dag zog, ua kom muaj kev kis tus mob, kev pheej hmoo ntawm kev puas tsuaj vim raug xaiv los ntawm lub koob tshuaj. Yog tias tomqab muag khoom tom qab muag tag, cov kab paj tau sau npe nrog cov kev mob loj bicentennial, lawv tau dhau los ua kev hem thawj rau lub neej, lossis ua rau neeg tuag: ua rau mob hlwb (kev coj tus cwjpwm tsis zoo, suav nrog kev tsis meej pem, pom kev tsis hnov ​​tsw, thiab ua cuav). Feem ntau ntawm VIPs tau ruaj ntseg los ntawm cov neeg mob uas ua tsis tau zoo ntawm tus nirok, lawv tau noj cov koob tshuaj ntawm cefepima, thiab rov pom zoo. Deacon's vipadka puag ncig ntawm lub rooj noj mov, yaki tau nqa tawm cov tshuaj noj, thiab tom qab ntawd lawv tau sib tw nrog urachuvannians rau lawv cov kev ua haujlwm nirok. Feem ntau ntawm cov neeg mob, cov tsos mob ntawm tus mob nephrotoxicity tau hloov pauv thiab tsis muaj kev lees paub txog cov nyhuv ntawm tus kab mob thiab / lossis kev kho mob ntawm hemodialysis.

Kev ua kom muaj cov kab mob tua cov kab mob txhawm rau kom muaj kev puas tsuaj ntawm cov leeg hauv plab hnyuv thiab ua rau muaj kev hlav ntawm clostridia. Npaj ua ntej rau cov neeg uas muaj taug lom Clostridium difficile, є Lub hauv paus tseem ceeb ntawm cov tshuaj tua kab mob hauv zej zog. Txhawm rau kuaj xyuas tus mob pseudomembranous mob plab, nws yog qhov tsim nyog yuav tau cog pob kws kho mob. Vipadok pseudomembranous colitis ntawm lub ntxa theem ntawm qhov mob hnyav tuaj yeem paub zoo txog kev npaj tshuaj. Nyob rau lub caij nplooj zeeg ntawm qhov kev thaj yeeb nyab xeeb thiab lub ntxa, koj yuav tsum ua tib zoo saib qhov xav tau thiab yoo mov, rau kev yoo mov thiab yoo cov tshuaj tua kab mob, txoj hauv kev zoo Clostridium difficile.

Maloimovirno, dab tsi yog lub hom phiaj ntawm kev thim tawm, yog tias tsis muaj pov thawj ntawm cov kab mob, thiab yog tias muaj kev tiv thaiv, yog tias muaj caij nyoog uas tsis muaj laj thawj rau nws yuav coj mus rau qhov pom. Kev tsis tseem ceeb ntawm kev dhuav rau Cefepim (zoo li kuv inshih tshuaj tua kab mob) tuaj yeem coj mus rau kev tsim kho superinfection. Nws yog ib qho tsim nyog yuav tsum tau ua kev rov ua ntu zus rau patsenta. Thaum lub sijhawm txhim kho ntawm superinfection, koj yuav tsum tau txais kev nkag mus uas tsim nyog. Bagato cephalosporins, suav nrog cefepim yog txuam nrog kev txo qis ntawm prothrombin. Ua ntej tsim pab pawg, koj yuav tsum nkag mus rau cov neeg mob nrog lub luag haujlwm ntawm lub qhov cub tawg, tab sis cov hais mav, cov hais mav, cov yoj, thiab tseem coj lub hom phiaj tsis tseem ceeb ntawm kev tawm tsam kev kho mob. Nws yog qhov tsim nyog los tswj hwm prothrombin ntawm pab pawg neeg mob thiab tib lub sijhawm ntawm txoj cai kos npe K. K.

Nyob rau lub sijhawm muaj kev tsis sib haum xeeb, cefepim tuaj yeem yog qhov zoo tab sis tsis zoo los ntawm kev kuaj mob Coombs ncaj qha. Thaum ua cov txheej txheem hematologic lossis hloov ntshav nrog ib pawg ntshav uas tau tsim nyob rau hauv ib txoj hauv kev tshaj lij, yog tias kev kuaj ntshav los tiv thaiv globulin tau ua, tab sis yog tias koj muaj Coombs kuaj rau cov neeg tshiab, niam tau raug muab tso tseg nrog cov tshuaj tua kab mob ntawm cephalosporins, peb tau txais cov txiaj ntsig zoo. Cefepim (cefepim hydrochloride) nrog khaws cia khaws cia cov neeg mob schlanko-plab hnyuv chua leeg hauv keeb kwm, tshwj xeeb tshaj yog colitis.

Bulo tau raug coj los, yog li L-arginine noj tshuaj kho ntshav qabzib sai sai nyob rau tib lub sijhawm hauv cov ntshav nrog cov koob tshuaj tsis tu ncua, kom ntau li 33 npaug qhov ntau tshaj qhov xav tau yog cefepime. Qhov cuam tshuam ntawm qhov qis qis qis hauv ib hnub tsis muaj.

Sposib zastosuvannya li dozi

Zvichayne dosvuvannya rau cov laus paub tab los ua 1 g, tom qab ntawd nkag mus rau sab hauv thiab sab hauv nrog ib nrab sijhawm ntawm 12 xyoos. Zvichayna tsis tseem ceeb іlkuvannya - 7-10 hnub, mob hnyav іnfektsії tuaj yeem noj ntau dua tsis tseem ceeb lіkuvannya.

Txawm li cas los xij, Kuv tau muaj lub sijhawm thiab cov lus qhia kom paub tseeb tias nws tsis muaj lub luag haujlwm los pom qhov rhiab ntawm cov kab mob me me, qhov nyuaj ntawm qhov nyuaj, thiab tseem muaj lub chaw pw zoo rau cov neeg muaj mob. Cov lus pom zoo yeej hloov kho tiag tiag rau cefepim rau overgrowth uas teev nyob rau hauv lub rooj.

Thaum muaj kev kub ntxhov ntawm tus kws muag khoom lub chaw haujlwm, muaj lub laj thawj ntawm kev npaj tshuaj sab hauv, nws yuav tsum khaws cov ntaub ntawv muaj kev nyab xeeb thiab muaj kev nyab xeeb, kom qhov kev ntsuas yuav zam tau.

Нфекції сечових ххіів yooj yim thiab nruab nrab nrau

500 mg - 1 g sab hauv, tab sis sab hauv

Pharmacological kev txiav txim

Nws yog rau cov khoom ua haujlwm tua kabmob ntawm 4 tiam. Tsim tshwj xeeb rau kev siv niam txiv. Nws ua tawm tsam cov kab mob gram-zoo thiab gram-tsis zoo, tshwj xeeb tshaj yog cov kab mob tiv thaiv cov tshuaj tua kabmob ntawm 2 thiab 3 tiam.

Txhawb kev tsim cov protein microbes, los ntawm cov neeg uas lawv tuag. Ntxiv mus, qhov tsawg kawg nkaus ntawm kev txiav txim siab yog tsawg dua li ntawm cov tshuaj analogues, uas tso cai rau koj siv cov tshuaj tsawg dua thiab siv cov koob tshuaj qis dua.

Nquag tawm tsam tej yam muaj sia:

• Staphylococcus aureus (suav nrog cov kab mob uas tsim cov beta-lactamase),
• S. hominis, S. Saprophyticus thiab lwm yam kab mob txawv ntawm staphylococci,
• Tus kab mob Streptococcus pyogenes thiab agalactiae, suav nrog cov kab mob uas tiv taus Penicillin,
• Streptococcus mob ntsws thiab lwm yam kab mob uas ua rau mob ntsws,
• Enterococcus faecalis thiab lwm hom kab mob enterobacteria,
• gram-negative aerobic muaj sia: Pseudomonas spp, Enterobacter spp. (suav nrog E. cloacae, E. aerogenes, E. sakazakii), Proteus spp. (suav nrog P. mirabilis, P. vulgaris), Acinetobacter calcoaceticus (suav nrog subfamilies Antratus, Ioffi), Aeromonas hydrophila, Capnocytophaga spp., Citrobacter spp. (suav nrog tus kab mob C. diversus, C. freundii), Campylobacter jejuni, Gardnerella vaginalis, Haemophilus ducreyi,
• H. mob khaub thuas thiab Parainfluenzae,
• Neisseria gonorrhoeae,
• anaerobic yam muaj sia: bacteroids, suav nrog melaninogenicus,
• Clostridium perfringens,
• Fusobacteria: Fusobacterium spp.

Abipim tau tsim tshwj xeeb rau kev siv ntawm niam txiv.

Cov tshuaj kuj tseem tuaj yeem siv tau yog tias nws tsis tuaj yeem tsim kom muaj cov pathogen. Cov cuab yeej no tau piav qhia los ntawm qhov tseeb tias cov tshuaj muaj zog tawm tsam ntau cov kab mob tseem ceeb.

Cov Tshuaj Pharmacokinetics

Cov tshuaj yog kom meej tso tom qab kev siv niam txiv. Qhov txiaj ntsig nruab nrab ntawm cov nquag sib xyaw nce mus txog qhov siab tshaj 60 feeb tom qab txhaj, tom qab ntawd txo qis.

Cov tshuaj muaj ntsiab lus ntawm cov tshuaj pom nyob hauv cov zis, cov kua tsib, peritoneal thiab prostatic tso zis, hnoos qeev, bronchial zais. Qee cov tshuaj muaj nyob hauv cov ntawv txuas ntxiv.

Ib nrab-lub neej ntawm cov khoom nquag ua hauj lwm yog 120 feeb, ywj siab ntawm kev muab tshuaj. Cumulation ntawm Abipim tsis pom txawm tias thaum siv cov koob tshuaj ntev ntev, uas tso cai rau kev siv tshuaj los kho cov kab mob sib kis loj.

Hauv lub cev, nws tawg rau methylpyrrolidine, uas hloov mus rau hauv methylpyrrolidone oxide sai sai. Nws yog tawm tawm siv glomeruli ntawm ob lub raum. Feem ntau cov tshuaj tawm los ntawm cov zis thiab tsuas yog ib feem me me - nrog quav. Nws khi rau cov protein ntau los ntawm kwv yees li 20%.

Lub sijhawm ib nrab-tshem tawm tau nce ntxiv hauv cov neeg mob uas lub raum tsis ua haujlwm, lawv xav tau kev kho kom haum. Hauv lwm qhov xwm txheej, cov cim ntawm pharmacokinetics tsis hloov pauv.

Lub sijhawm ib nrab-tshem tawm tau ntau ntxiv hauv cov neeg mob uas lub raum tsis ua haujlwm.

Cov Yuav Tsum Muaj

Muaj cov contraindications rau noj:

• cov tshuaj tiv thaiv tsis haum rau cefepime thiab L-arginine, ib qho yeeb tshuaj los ntawm koob ntawm cephalosporins,
• kev ua xua los qhia txog ntawm cephalosporins rau hauv lub cev,
• kev ua xua ntawm cov piam thaj oxidation.

MP yog qhia rau kis mob ntawm daim tawv nqaij.
MP yog qhia rau poj niam pathologies.MP yog qhia rau cov kab mob ntawm txoj kev ua pa.

Yuav ua li cas coj Abipim

Koob tshuaj rau cov laus yog 1 g nyob rau ib hnub. Nws yog txhaj rau hauv cov leeg nqaij lossis rau hauv cov hlab ntsha 2 zaug hauv ib hnub nrog rau kev so 12 teev. Lub sijhawm tswj hwm tib lub sijhawm yuav tsum raug saib xyuas kom tsis txhob muaj kev phiv thiab txhim kho cov txiaj ntsig kev kho mob.

Qhov ntau npaum li cas yuav txawv nyob ntawm seb hom pathogen thiab qhov siv ntawm cov txheej txheem sib kis.

Muaj ntau txoj kev xaiv tshuaj thiab cov kev tswj hwm tshuaj:

• nrog pathologies ntawm qhov mob ntawm lub tso zis - los ntawm 0.5 mus rau 1 g 2 zaug hauv ib hnub,
• nrog rau lwm yam kev kis mob ntawm mob sib khuav-qib nruab nrab - 1 g ua ke lossis tso leeg 2 zaug hauv ib hnub,
• nrog cov kab mob loj - 2 g ntawm cov tshuaj 2 zaug hauv ib hnub,
• hauv cov kev mob txaus ntshai - 2 g ib hnub, muab faib ua 3 koob tshuaj txhua 8 teev.

Txhawm rau txhawm rau tiv thaiv kev kis kab mob tom qab, nws yog ib qho tsim nyog siv tshuaj rau ib teev ua ntej kev phais mob (2 g txhua ib nrab teev), thiab tom qab ua haujlwm tiav, ib qho ntxiv 0.5 g ntawm cov tshuaj yog txhaj rau hauv cov hlab ntsha. Yog tias xav tau kev cuam tshuam ntev ntev, ces yuav tsum tau txhaj tshuaj ntxiv 12 teev tom qab thawj zaug muab thawj zaug.

Kev txhaj tshuaj rau cov leeg yog qhov zoo dua, nrog lub koob raug tsav mus tob rau hauv cov leeg nqaij.

Hauv kev mob nyhav, kev tswj hwm ntawm Abipim yog qhov tsim nyog.

Nws yog txhaj rau hauv cov leeg nqaij lossis rau hauv cov hlab ntsha 2 zaug hauv ib hnub nrog rau kev so 12 teev.

Cov lus qhia tshwj xeeb

Hauv cov neeg mob uas muaj kev pheej hmoo ntawm kev mob txhab ntxiv nrog keeb kwm ntawm hloov pob txha hloov, MP kev ua haujlwm tsawg dua. Abipimom monotherapy tuaj yeem tsis txaus thiab tsis muaj txiaj ntsig, yog li, kev teem caij ntawm lwm tus neeg sawv cev yog tsim nyog. Hauv qhov no, tus neeg mob tuaj yeem txhim kho neutropenia vam meej, yog li, thaum kho, nws yog qhov yuav tsum tau soj ntsuam cov ntshav tas li.

Ua ntej pib kev kho mob, koj yuav tsum tau txiav txim siab seb tus neeg mob puas tau muaj kev cuam tshuam sai rau cefepime thiab lwm yam cephalosporins. Txhua yam kev phiv tsis haum, xws li cov tshuaj yuav tsum tau ua kom zoo. Yog tias muaj qhov tsis haum tshuaj tshwm sim, qhov chaw tos txais yuav tsum nres sai sai.

Yog tias muaj cov tsos mob hnyav tshwm sim, tus neeg mob yuav tsum tau txhaj tshuaj Adrenaline.

Yog tias pom muaj mob hnyav, tus neeg mob yuav tsum raug tswj hwm Adrenaline lossis Norepinephrine.

Kev siv cov tshuaj tua kabmob ua haujlwm nrog ntau qhov kev pom zoo tuaj yeem ua rau kev txhim kho pseudomembranous o ua rau lub plab hnyuv loj. Qhov no tuaj yeem tshwm sim ua raws plab. Cov ntaub ntawv me me muaj peev xwm kis tau sai dhau uas tsis muaj kev kho tshwj xeeb. Nrog rau lwm txoj kev ntawm kev ua haujlwm ntawm cov hnyuv, cephalosporins yuav tsum tau ua tib zoo kho, saib xyuas tib neeg cov tshuaj tiv thaiv.

Kev siv tshuaj noj tuaj yeem pab txhawb kev tsim kho kev ua si.

Kev siv ntawm ib qho tshuaj tua kab mob antimicrobial, suav nrog thiab Abipima, nqa nrog nws ua kom muaj kev hloov pauv hauv cov kab hauv cov kab mob, uas ua rau muaj qhov pom ntawm clostridia hauv txoj hnyuv. Cov txheej txheem no pab txhawb kev txhim kho cov tshuaj tua kab mob sib kis.

Txiag tej menyuam

Cov cuab yeej tuaj yeem siv rau menyuam yaus, pib txij lub hlis. Hauv qhov no, qhov koob tshuaj tau xaiv ncaj qha nyob ntawm lub hnub nyoog ntawm tus menyuam thiab qhov ntsuas ntawm qhov sib kis ntawm cov txheej txheem sib kis.

Hauv cov neeg mob kev txom nyem los ntawm lub raum pathologies, tej zaum yuav muaj kev pom dav txaus tom qab cov tshuaj.
Hauv cov neeg mob kev txom nyem los ntawm lub raum pathologies, tej zaum yuav muaj myoclonus tom qab cov tshuaj.
Hauv cov neeg mob kev txom nyem los ntawm lub raum pathologies, tej zaum yuav muaj kev qaug dab peg tom qab cov tshuaj.

Cov neeg hnyav 40 kg lossis ntau dua tsis tas yuav hloov pauv koob tshuaj.

Siv thaum cev xeeb tub thiab lactation

Kev siv ntawm Abipim yog qhov tsis lees paub hauv lub sijhawm 1 lub hlis. Yav tom ntej, MP tau sau tseg yog tias cov txiaj ntsig zoo dua li qhov pheej hmoo txaus ntshai.

Cov tshuaj muaj peev xwm nkag rau hauv niam mis thiab ua rau kev loj hlob cuam tshuam ntawm tus menyuam, yog li ntawd nws raug nquahu kom tsis txhob pub mis niam thaum kho nrog tus MP no.

Daim ntawv thov rau lub raum khiav tsis zoo

Nws yog ib qho tsim nyog yuav tau kho qhov tshuaj ntawm cov tshuaj txhawm rau kom tiv thaiv kev lom. Nrog rau kev txo qis ntawm creatinine kev tshem tawm, cov koob tshuaj tau raug txo kom thiaj li them nyiaj rau cov qeeb tso tawm. Hauv cov kab mob hauv lub raum, nws yog qhov zoo dua los qhia kho kev kho kom zoo rau cov tshuaj kom txo qis cov kev tsis zoo ntawm lub raum pathology.

Hauv cov neeg mob kev txom nyem los ntawm lub raum pathologies, cov kev mob tshwm sim tom qab tau sau tseg:

• tabkaum thiab tsis meej pem, hais tawm lus tso dag, hnov ​​ntsej muag, tsis nco qab,
• myoclonia
• cramps.

Xws li cov xwm txheej phom sij tau sau tseg rau hauv cov neeg uas muab Abipim siv tshuaj ntau kawg.

Daim ntawv thov rau lub siab ua haujlwm tsis zoo

Kev ceev faj yuav tsum tau siv rau thaum muaj mob rau daim siab, mob siab thiab mob ntsws.

Yog tias qhov koob tshuaj tshaj li lub hlwb, lub hlwb yuav tshwm sim.
Yog tias qhov koob tshuaj tau tshaj dhau lawm, kev poob siab tsis xis nyob yuav tshwm sim.
Yog tias qhov koob tshuaj tshaj qhov ua ntej, lub cev tsis xeev yuav tshwm sim.

Kev cuam tshuam nrog lwm yam tshuaj

Nws yog ib qho tsim nyog los saib xyuas kev ua haujlwm ntawm lub raum, tshwj xeeb tshaj yog tias tus neeg mob siv lwm yam tshuaj nephrotoxic. Qhov no yog qhov tseem ceeb thaum noj furosemide thiab lwm yam tshuaj diuretics. Qee qhov xwm txheej, nrog kev sib txuam ntawm cov tshuaj no, ib qho nce ntawm nephrotoxicity tau sau tseg.

Tshaj rau cov tshuaj zoo li no:

• saline daws
• piam thaj tov
• piam thaj nrog lactate.

Nws tsis pom zoo kom nkag mus rau tib lub sijhawm:

• Metronidazole,
• Vancomycin
• Gentamicin,
• Tobramycin sulfate,
• Netromycin sulfate.

Abiprim tsis pom zoo kom siv rau hauv ib txhij nrog metronidazole.
Abiprim tsis pom zoo rau kev tswj hwm ib txhij nrog vancomycin.
Abiprim tsis pom zoo kom noj nrog tib lub caij nyoog nrog gentamicin.

Kuv tuaj yeem yuav yam tsis tas yuav tshuaj

Hauv ntau cov chaw muag tshuaj, cov khw muag tshuaj online tuaj yeem yauv tau yam tsis tas yuav tshuaj.

Zebopim yog ib qho ntawm cov yeeb yaj kiab ntawm Abipim.
Cefepim yog ib qho ntawm cov yeeb yaj kiab ntawm Abipim.
Cefuroxime yog ib qho ntawm cov yeeb yaj kiab ntawm Abipim.

Kev txheeb xyuas txog Abipime

Irina, hnub nyoog 35 xyoo, Nizhny Novgorod: “Nrog kev pab los ntawm Abipim, Kuv tuaj yeem kho mob cystitis, uas tsis tau kho nrog lwm tus neeg sawv cev rau tshuaj tua kab mob. Kuv tau noj tshuaj rau 10 hnub (2 hnoos 500 mg ib zaug). ib qho kev hloov kho ruaj khov los txhawb txoj kev tiv thaiv kab mob thiab tiv thaiv kom tsis txhob rov kis mob ntawm lub zais zis. "

Oleg, hnub nyoog 40 xyoo, Komsomolsk-on-Amur: "Nrog kev pab ntawm Abipim, nws kho tau mob ntsws zoo heev. Nws tau noj tshuaj rau 10 hnub. Nws twb tau los ntawm 3 hnub ntawm kev kho mob, tus tsos mob ntawm tus kab mob tsawg zuj zus, hnoos thiab kub taub hau ploj mus. Tsis muaj kev phiv thaum lub sijhawm kho mob tshuaj. Kuv tabtom kawm ib chav ntawm kev rov ua haujlwm li qub hnyuv microflora, vim hais tias tom qab Abipim nws tig los ua kev ntxhov siab me ntsis. "

Polina, hnub nyoog 28 xyoo, Nizhnevartovsk: "Cov tshuaj tau pab tshem tawm tus kabmob kis kabmob ntawm poj niam lub cev xeeb tub. Cov tshuaj tua kabmob no tau pom zoo zoo, nws tau ua rau muaj kev txhim kho rau hnub 3 ntawm txoj kev kho. Kuv yuav tsum tau kho rau ib lub limtiam. mob thiab mob thaum tso zis. "