28 April, 2024
    Kev khomob thiab kev tiv thaiv

    Metformin Canon: cov lus qhia rau kev siv thiab vim li cas nws xav tau

    Metformin Canon: cov lus qhia rau kev siv thiab tshuaj xyuas

    Lub npe Latin: Metformin-Canon

    ATX Code: A10BA02

    Tus nquag ua hauj lwm: Metformin (Metformin)

    Cov chaw tsim khoom: KANONFARMA NTAU LAWM, CJSC (Russia), NPO FarmVILAR, OOO (Russia)

    Hloov kho cov lus piav qhia thiab yees duab: 10.24.2018

    Cov nqi hauv khw muag tshuaj: los ntawm 85 rubles.

    Metformin Canon yog qhov tshuaj hypoglycemic.

    Tso tawm daim ntawv thiab muaj pes tsawg leeg

    Dosage daim ntawv tso tawm ntawm Metformin Canon - ntsiav tshuaj-coated ntsiav tshuaj:

    • Metformin Canon 500 mg: biconvex, puag ncig, yuav luag dawb lossis dawb (hauv cov hlwv ntim ntawm 10 lossis 15 pcs., Hauv ib pob ntawv los ntawm 3, 5, 6, 10 lossis 12 pob ntawm 10 pcs., 2, 4 lossis 8 ntim ntawm 15 pcs.)
    • Metformin Canon 850 mg thiab 1000 mg: biconvex, oval, yuav luag dawb lossis dawb (hauv cov hlwv ntim ntawm 10 pcs., Hauv ib pob ntawv los ntawm 3, 5, 6, 10 lossis 12 pob).

    Txheej Txheem 1 ntsiav tshuaj Metformin Canon 500 mg, 850 mg thiab 1000 mg, feem:

    • cov tshuaj nquag: metformin hydrochloride - 0.5, 0.85 lossis 1 g,
    • Cov khoom siv pabcuam: macrogol (polyethylene glycol 6000) - 0.012, 0.020 4 lossis 0.024 g, talc - 0.003, 0.005 1 lossis 0.006 g, povidone - 0.047, 0.079 9 lossis 0.094 g, sodium stearyl fumarate - 0.003, 0.005 1 lossis 0.006 g, sodium carboxymethyl starch - 0.008, 0.013 6 lossis 0.016 g, pregelatinized hmoov txhuv nplej siab - 0.027, 0.045 9 lossis 0.054 g,
    • zaj duab xis txheej: Opadry II dawb - 0.018, 0.03 lossis 0.036 g, suav nrog talc - 0.003 132, 0.005 22 lossis 0.006 264 g, titanium dioxide - 0.002 178, 0.003 63 lossis 0.004 356 g, macrogol (polyethylene glycol) - 0.004 248, 0.007 08 lossis 0.008 496 g, polyvinyl cawv 0.008 442, 0.014 07 lossis 0.016 884 g.

    Cov Tshuaj Hauv Tshuaj

    Cov tshuaj ua kom nquag plias ntawm cov tshuaj, metformin, yog ib qhov ncauj hypoglycemic tus neeg sawv cev koom nrog cov pab pawg biguanide.

    Cov kev ua ntawm Metformin Canon, vim yog cov tshuaj yeeb dej caw nyob hauv nws cov muaj pes tsawg leeg:

    • ib qho kev txo qis hauv cov ntshav qabzib concentration los ntawm kev siv nws cov kev siv rau hauv cov ntaub so ntswg ntau dua los ntawm kev ua rau lawv lub cev tsis txaus siab rau insulin (feem ntau striated cov leeg, kom tsawg dua adipose nqaij), txo nws txoj kev nqus los ntawm txoj hnyuv thiab inhibiting daim siab gluconeogenesis hauv cov neeg mob ntshav qab zib mellitus. ,
    • stimulation ntawm intracellular glycogenesis los ntawm kev ua kom glycogen synthase,
    • tsis muaj kev tsa ntawm cov insulin secretion thiab hypoglycemic kev txiav txim siab hauv cov neeg muaj kev noj qab haus huv (tsis zoo li sulfonylurea derivatives),
    • qhov ua kom poob qis hauv cov ntsiab lus hauv cov ntshav ntshav ntawm lipoproteins uas tsis muaj ntau ntau, cov roj cholesterol thiab triglycerides,
    • stabilization lossis poob phaus,
    • fibrinolytic nyhuv los ntawm kev tsuj cov ntaub so ntswg hom plasminogen activator inhibitor.

    Cov Tshuaj Pharmacokinetics

    • kev nqus: nws nqus tau los ntawm lub plab zom mov thaum noj ntawm qhov ncauj yog 48-52%, kev noj ib txhij qeeb thiab txo nws txoj kev nqus, qhov tiag bioavailability txawv ntawm 50 txog 60%, Cmax (qhov siab tshaj plaws hauv cov ntshav) yog 2 mcg rau 1 ml, TSmax (lub sijhawm kom ncav cuag qhov siab tshaj plaws) - 1.81–2.69 h,
    • kev faib tawm: muab faib sai sai rau hauv cov ntaub so ntswg, nkag mus rau hauv cov ntshav liab, nthuav tawm hauv lub raum, mob siab thiab mob qog, lub ntim faib (rau ib koob ntawm 0.85 g) yog 296-1012 l, muaj qhov sib txuas me me nrog plasma protein,
    • metabolism: yog heev tsis zoo metabolized,
    • kev nthuav tawm: feem ntau tsuas yog nyob hauv daim ntawv hloov pauv los ntawm lub raum, nws qhov kev tshem tawm hauv cov neeg noj qab haus huv yog 0.4 l hauv 1 min, T1/2 (ib nrab-lub neej) yog 6.2 teev (thawj pib sib txawv ntawm 1.7–3 teev, lub davhlau ya nyob twg - 9-17 teev), yog tias lub raum tsis ua hauj lwm T1/2 nce thiab muaj kev pheej hmoo ntawm kev txuam nrog tshuaj.

    Kev ntsuas rau siv

    • cov neeg laus (tshwj xeeb tshaj yog rog): kho monotherapy lossis kev sib txuas nrog kev kho mob nrog insulin lossis lwm yam kev tiv thaiv kab mob hauv lub qhov ncauj ntawm tus mob ntshav qab zib hom 2 hauv qhov kev tawm dag zog lub cev thiab kev noj zaub mov tsis muaj txiaj ntsig,
    • Cov menyuam yaus tshaj 10 xyoo: kev kho mob monotherapy lossis kev sib txuas nrog kev kho mob nrog insulin hom 2 ntshav qab zib mellitus.

    Leej twg yog tus muab tshuaj rau

    Txog tam sim no, cov npe ntawm kev taw qhia rau kev noj cov Metformin Canon tsuas yog muaj 2 hom mob ntshav qab zib thiab nws cov kev mob ua ntej. Tsis ntev los no, qhov ntau ntawm cov tshuaj tau nthuav dav. Lub peev xwm ntawm nws siv nyob rau hauv cov neeg muaj rog, mob vascular, dyslipidemia raug txiav txim siab.

    Cov lus qhia rau kev teem caij los ntawm cov lus qhia:

    • Them nyiaj mob ntshav qab zib rau cov neeg laus thiab menyuam yaus txij li 10 xyoo. Cov tshuaj yuav tsum muaj ntxiv nrog kev noj haus thiab kev tawm dag zog. Siv nrog lwm cov ntsiav tshuaj hypoglycemic thiab insulin yog tso cai. Kev soj ntsuam zoo tshaj plaws yog pom hauv cov neeg mob ntshav qab zib.
    • Txhawm rau tiv thaiv kev txhim kho ntshav qab zib hauv cov neeg muaj lub siab nyiam ua kom cov metabolism metabolism. Cov tshuaj yog raug sau tseg yog tias tus neeg mob tsis tuaj yeem ua tiav qhov glycemia nrog kev noj zaub mov noj thiab kis las, thiab kev pheej hmoo ntawm ntshav qab zib tau raug soj ntsuam siab. Metformin tshwj xeeb tshaj yog pom zoo rau cov neeg muaj hnub nyoog 60 xyoo uas mob rog heev, tsis muaj mob caj ces (ntshav qab zib hauv ib leej niam thiab txiv), lipid metabolism tsis txaus, kub siab, thiab keeb kwm mob ntshav qab zib hauv lub cev xeeb tub.

    Tsis zoo li Metformin

    Txhawm rau qhia qhov chaw ntawm cov tshuaj Metformin Canon nrog ntau lwm cov ntsiav tshuaj hu ua Metformin, peb tig mus rau keeb kwm. Biguanides tau siv rau hauv cov tshuaj rau ntau pua xyoo. Txawm nyob hauv Nrab Hnub nyoog, kev tso zis tsis haum tau raug kho nrog infusions los ntawm Galega officinalis cog. Hauv Tebchaws Europe, nws tau paub nyob rau hauv ntau lub npe - Fabkis lilac, tus xibfwb nyom, tshis (nyeem txog tshis tshuaj), hauv tebchaws Russia lawv feem ntau hu ua cov paj huab cua Fabkis.

    Cov lus zais ntawm cov nroj tsuag no tsis tau yoog thaum pib ntawm lub xyoo pua 20th. Cov tshuaj yeeb yaj kiab, uas tau muab cov suab thaj txo qis dua, tau muab lub npe guanidine. Cais tawm ntawm cov nroj tsuag, guanidine hauv ntshav qab zib pom cov nyhuv tsis muaj zog, tab sis siab toxicity. Kev tshawb rau qhov txo cov khoom qab zib zoo tsis tau tso tseg. Hauv xyoo 1950, cov kws tshawb fawb tau khom rau tsuas yog kev nyab xeeb ntawm kev loj hlob - metformin. Cov tshuaj tau muab lub npe Glucophage - lub suab thaj absorber.

    Thaum xaus xyoo 1980, nws tau pom tias ib qho tseem ceeb tshaj plaws ua rau muaj ntshav qab zib yog insulin tsis kam. Tom qab tshaj tawm ntawm kev tshawb pom ntawm cov kws tshawb fawb, kev txaus siab nyob rau hauv glucophage tau nce ntau. Tshawb nrhiav qhov tseeb txog qhov ua tau zoo, kev nyab xeeb, kev txhim kho ntawm cov tshuaj, kaum tawm txoj kev tshawb nrhiav qhov tseeb. Txij xyoo 1999, cov ntsiav tshuaj nrog metformin tau dhau los ua thawj hauv cov npe pom zoo rau ntshav qab zib. Lawv nyob hauv thawj qhov chaw txog niaj hnub no.

    Vim qhov tseeb hais tias Glucofage tau tsim tawm ntau xyoo dhau los, cov ntsiab lus ntawm kev tiv thaiv patent rau nws tau ntev dhau los. Raws li txoj cai, ib lub tuam txhab tshuaj twg tuaj yeem tsim cov tshuaj metformin. Ntau pua ntawm Glucophage generics tam sim no tau tshaj tawm thoob ntiaj teb, feem ntau ntawm lawv nyob rau hauv lub npe Metformin. Hauv tebchaws Lavxias, muaj ntau dua kaum ob lub chaw tsim khoom ntawm cov ntsiav tshuaj nrog metformin. Cov tuam txhab uas tau yeej txoj kev cia siab ntawm cov neeg mob feem ntau ntxiv qhov qhia tau ntawm cov neeg tsim khoom rau lub npe ntawm cov tshuaj. Metformin Canon yog cov khoom lag luam ntawm Canonfarm Ntau Lawm. Lub tuam txhab tau tsim tawm cov tshuaj rau 20 xyoo. Lawv ua tiav raws thoob ntiaj teb cov cai thiab cov qauv zoo. Canonfarm npaj tswj kev tswj ntau theem, pib los ntawm cov khoom siv siv, xaus nrog cov ntsiav tshuaj npaj tau. Raws li cov kws kho ntshav qab zib, Metformin Canon yog ze li sai tau rau qhov qub Glucophage hais txog kev ua hauj lwm zoo.

    Canonpharma ua cov tshuaj metformin hauv ntau yam:

    TshuajTsuas tshuajTus nqi kwv yees, rub.
    30 tab.60 tab.
    Metformin Canon500103195
    850105190
    1000125220
    Metformin Ntev Canon500111164
    750182354
    1000243520

    Cov lus qhia rau coj cov tshuaj

    Cov kev qhia ua qhia txog lub luag haujlwm tseem ceeb ntawm kev noj zaub mov thaum lub sijhawm kho tag nrog rau tshuaj. Tus neeg mob xav tau kom txo tsawg cov zaub mov carbohydrate (tus kws kho mob txiav txim siab qhov yuav txo qis ntawm tus mob mus rau hauv tus kab mob loj npaum li cas), faib lawv rau hauv cov qhov sib luag txhua hnub. Yog tias koj rog dhau lawm, kev noj zaub mov kom tsawg-tsawg pom zoo kom yog. Qhov tsawg kawg nkaus calories kom tsawg thaum noj Metformin Canon yog 1000 kcal. Noj zaub mov kom nruj ua rau muaj kev phiv.

    Yog tias tus mob ntshav qab zib tsis tau noj dua yav dhau los metformin, kev kho mob pib nrog qhov ntau npaum ntawm 500-850 mg, cov ntsiav tshuaj tau qaug cawv rau lub plab tag nrho ua ntej yuav mus pw. Thaum xub thawj, qhov kev pheej hmoo ntawm kev phiv yog qhov tshwj xeeb tshaj yog, yog li cov koob tshuaj tsis raug nce rau 2 lub lis piam. Tom qab lub sijhawm no, ntsuas cov qib ntawm glycemia txo qis thiab, yog tias tsim nyog, ua kom ntau dua cov tshuaj. Txhua 2 lub lis piam koj tuaj yeem ntxiv los ntawm 500 txog 850 mg.

    Tshaj tawm kev pub nkag - 2-3 zaug hauv ib hnub, thaum ib ntawm kev txais yuav tsum yog yav tsaus ntuj. Raws li kev txheeb xyuas, rau feem ntau ntawm cov neeg mob, kev kho mob glycemia li qub yog txaus 1500-2000 mg rau ib hnub (3x500 mg lossis 2x850 mg). Qhov koob tshuaj ntau tshaj plaws raws li cov lus qhia yog 3000 mg (3x1000 mg) rau cov neeg laus, 2000 mg rau menyuam yaus, 1000 mg rau cov neeg mob raum tsis ua haujlwm.

    Yog hais tias tus neeg mob ua raws li kev noj haus, yuav tsum siv tshuaj metformin ntawm qhov ntau kawg, tab sis nws tsis tswj kom ua tiav cov nyiaj them rau ntshav qab zib, tus kws kho mob yuav qhia ib qho kev txo qis hauv insulin synthesis. Yog tias muaj cov tshuaj insulin tsis txaus ntseeg, cov tshuaj hypoglycemic uas txhawb cov txiav ua ke yog ntxiv cov kws kho mob.

    Dab tsi tshwm sim phiv

    Hauv plab hnyuv plab zom mov, cov concentration ntawm metformin yog pua pua ntau dua hauv cov ntshav, daim siab thiab lub raum. Feem ntau cov kev mob tshwm sim los ntawm cov tshuaj cuam tshuam nrog qhov no. Txog 20% ​​ntawm cov neeg mob thaum pib noj Metformin Canon muaj mob plab zom mov: xeev siab thiab zawv plab. Feem ntau, lub cev tswj kom yoog nrog cov tshuaj, thiab cov tsos mob no ploj lawv tus kheej hauv 2 lub lis piam. Txhawm rau txo qhov mob ntawm cov kev mob tshwm sim, cov lus qhia rau kev siv pom zoo kom noj cov tshuaj nrog zaub mov, pib kho nrog qhov tsawg kawg nkaus.

    Thaum muaj kev tiv thaiv tsis zoo, kws kho mob tau hais qhia kom hloov mus rau metformin ntsiav tshuaj ua siv cov thev naus laus zis kawg. Lawv muaj cov qauv tshwj xeeb, ua tsaug uas cov tshuaj nquag nkag mus rau hauv cov ntshav me me hauv qee qhov me me. Hauv qhov no, qhov kam rau ntawm cov tshuaj muaj zog tuaj yeem txhim kho. Canonfarm lub caij nyoog ntev-cov nyhuv tshuaj hu ua Metformin Long Canon. Raws li kev txheeb xyuas, lawv yog ib qho kev xaiv zoo rau cov tshuaj Metformin Canon nrog kev nkag tsis tau.

    Cov ntaub ntawv hais txog qhov tsawg zaus ntawm kev phiv los ntawm cov lus qhia:

    Phiv Teeb meem ntawm MetforminQhov tshwm sim ntau zaus,%
    Cov kab mob lactic acidosis1
    Kev mob plab zom mov> 10
    Kev ua xua tsis haumTsuas yog 147 rubles!

    Cov Yuav Tsum Muaj

    Cov kab mob sib kis feem ntau hauv cov lus qhia rau kev siv yog kev sim los ntawm tus tsim khoom los tiv thaiv lactic acidosis. Metformin tsis tuaj yeem raug sau tseg:

    • yog tias tus neeg mob lub raum tsis ua haujlwm thiab GFR nrog tsawg dua 45,
    • nrog rau hypoxia loj heev, uas tuaj yeem tshwm sim los ntawm kab mob ntsws, lub plawv tsis ua haujlwm, plawv nres, ntshav liab,
    • mob siab,
    • Quav Cawv
    • yog tias tus mob ntshav qab zib yav dhau los muaj cov kab mob lactic acidosis, txawm tias nws tsis tshwm sim los ntawm metformin,
    • thaum cev xeeb tub, tsuas yog cov tshuaj insulin raug tso cai los ntawm cov tshuaj hypoglycemic nyob rau lub sijhawm no.

    Cov tshuaj tau muab tso tseg nrog ketoacidosis, thaum kho cov mob hnyav, raug mob hnyav, tshem tawm lub cev qhuav dej, ua ntej kev phais mob. Metformin raug txiav tawm 2 hnub ua ntej Xoo hluav taws xob nrog tus neeg sawv cev sib piv, thiab kev kho mob tau rov ua dua 2 hnub tom qab kev kawm.

    Cov ntshav qab zib ua ntu zus ntev yog feem ntau nrog lub plawv tsis ua haujlwm. Hauv cov lus qhia, tus kab mob no hais txog kev sib txuas rau kev kho mob nrog metformin, tab sis hauv kev coj ua, cov kws kho mob yuav tsum tau muab tshuaj rau cov neeg mob ntawd. Raws li kev tshawb fawb ua ntej, metformin hauv cov neeg mob plawv tsis tsuas txhim kho cov nyiaj mob ntshav qab zib, tab sis kuj tseem txo qis kev tuag thiab txo cov kev mob nkeeg. Kev pheej hmoo ntawm cov kab mob lactic acidosis hauv qhov no nce insignificantly. Yog tias qhov kev ua no tau lees paub, lub plawv tsis ua haujlwm yuav raug cais tawm ntawm cov npe ntawm contraindications.

    Tso tawm hom

    Cov tshuaj yog tsim nyob hauv ntau qhov sib txawv, thiab ib qho ntawm lawv yog 850 mg. Cov lus qhia rau "Metformin Canon" muaj nyob hauv txhua pob. Cov khoom siv yog tsim nyob rau hauv daim ntawv ntawm biconvex oval ntsiav tshuaj, uas muaj xim dawb.

    Cov teeb meem Pharmacological

    Cov tshuaj siv hauv cov lus nug yog ib tus neeg sawv cev hypoglycemic, uas yog tus xa mus ua biguanides. Nws tuaj yeem tshwm sim hauv daim siab, hauv lub raum thiab hauv cov qog qaub ncaug. Qhov ua tau zoo ntawm cov tshuaj no cuam tshuam ncaj qha nrog kev muaj peev xwm inhibit gluconeogenesis. Nws cov hauj lwm zoo yog tshwm sim los ntawm kev tsim cov acids dawb thiab oxidation ntawm cov rog, uas cuam tshuam rau cov nyhuv pharmacological ntawm cov tshuaj:

    • Txo cov piam thaj ntau ntau.
    • Ua rau nkag siab ntau ntxiv ntawm cov kab mob insulin nrog rau kev txhim kho cov piam thaj kom zoo dua qub, acid oxidation thiab kev siv cov piam thaj.
    • Txo kev nqus ntawm kev cuam tshuam ntawm cov thyroid-stimulating hormone thiab qabzib los ntawm kev ua haujlwm.
    • Cov roj (cholesterol) qis dua, triglyceride thiab lipoprotein tsawg ceev.
    • Cov txheej txheem ntawm normalizing ntshav coagulation nrog rau kev txhim kho nws cov rheological zog, uas txo kev pheej hmoo ntawm cov ntshav txhaws.
    • Kev hnyav lub cev yog ib feem ntawm kev kho mob rog.

    Cov lus qhia tshwj xeeb

    Raws li cov lus qhia rau Metformin Canon, 850 mg, thaum siv cov tshuaj no, qabzib tswj tom qab noj mov thiab hauv plab tsis zoo yog qhov tseem ceeb heev, nrog rau kev saib xyuas thaj tsam ntawm creatinine (nrog rau cov raum ua haujlwm ib xyoos ib zaug, thiab rau cov neeg laus nrog kev txo qis plaub zaug hauv kaum ob hlis). Yog tias muaj mob ntawm cov leeg thiab lub plab, ntuav thiab tsis muaj zog hauv lub cev, tawm tsam keeb kwm ntawm malaise (cov tsos mob ntawm cov kab mob lactic acid), thiab, ntxiv rau, nrog cov cim ntawm kab mob genitourinary mob lossis mob ntsws, koj yuav tsum tsis txhob noj tshuaj, thiab tom qab ntawd sab laj nrog kws kho mob.

    Thaum siv cov tshuaj nrog lwm tus neeg hypoglycemic, lub peev xwm sai psychomotor cov tshuaj tiv thaiv poob qis. Thaum lub sij hawm siv tshuaj kho mob, ib qho yuav tsum tsis kam haus cawv kom tsis txhob muaj qhov tshwm sim ntawm cov kab mob lactic acidosis. Cov tshuaj yog contraindicated thaum cev xeeb tub, tawm tsam keeb kwm ntawm lactation, pub mis ntuj yog nres yog tias xav tau kev siv ntawm "Metformin Canon". Rau qhov poob phaus, cov tshuaj no feem ntau siv.

    Kev tshem tawm cov phaus uas hnyav dhau los yog qhov nyuaj yog ib txoj haujlwm nyuaj hauv kev xav ntawm lub hlwb thiab lub dag lub zog, vim tias nws yuav tsum siv zog ntau thiab muaj kev hloov pauv ntau hauv txoj kev ua neej ib txwm nyob. Hauv kev hais txog qhov no, tsis tsuas yog cov khoom noj khoom haus, tab sis kuj ncaj qha rau cov neeg uas xav kom poob phaus, ua ntu zus mus nrhiav qhov yooj yim ntawm kev ua kom lub cev yuag. Xyoo tsis ntev los no, nws tau dhau los ua kev siv tshuaj rau cov neeg poob ceeb thawj uas tsis yog tsim rau kom poob phaus, tab sis qhia cov txiaj ntsig zoo li no hauv kev kho mob ntawm qhov pib.

    Ib ntawm cov tshuaj no yog Metformin Canon. Cov tshuaj no tau sau tseg los ntawm kws kho mob txhawm rau txo qis cov piam thaj kom muaj ntshav qab zib. Cov neeg ncaws pob thiab cov neeg tawm dag zog yog thawj zaug siv Metformin Canon rau qhov hnyav poob. Ntxiv mus, tau txais ntau cov kev soj ntsuam zoo, cov tshuaj pib mus deb dhau li kis las thiab kho mob voj voog.

    Yog li, hauv kev sib ntaus cov tiv thaiv kev rog nrog ntshav qab zib, cov tshuaj txo cov ntshav qabzib ntau ntau, uas tshem tawm kev xav ntau dhau nrog qhov nqhis rau cov khoom qab zib. Cov neeg ncaws pob thiab cov ntxhais noj zaub mov uas tsis muaj ntshav qab zib siv cov tshuaj peb zaug hauv ib hnub rau 500 milligrams rau nees nkaum ob hnub (tom qab ntawd koj xav tau so rau ib hlis).Thaum noj, kev tawm dag zog lub cev yuav tsum tau ua ke nrog kev tshem tawm cov zaub mov carbohydrate thiab cov rog los ntawm kev noj haus.

    Yeeb tshuaj sib cuam tshuam

    Raws li qhia los ntawm cov lus qhia ntawm Metformin Canon, 850 mg, nws yog contraindicated yuav siv cov ntsiav tshuaj no ob hnub ua ntej thiab tom qab kev tshawb fawb siv cov tshuaj radiopaque. Muaj tshuaj uas yuav tsum tau siv nrog txoj kev kho peb piav qhia zoo:

    • Qhov no yog, ua ntej ntawm tag nrho, Danazol, uas ua rau muaj peev xwm ua tau ntawm kev ua haujlwm hyperglycemic.
    • "Chlorpromazine" hauv kev txhaj tshuaj ntau (100 milligrams ib hnub) thiab tshuaj antihypertensive tsub kom cov concentration ntawm cov piam thaj hauv cov ntshav ntau dua. "Chlorpromazine" txo qis kev tso tawm ntawm cov kua dej.
    • Hauv qee qhov ua piv txwv, ketosis tshwm sim los ntawm glucocorticosteroids, kev tso kua nplaum tawm qis thiab nws cov concentration nce ntxiv.
    • Ntxees diuretics ua rau muaj kev pheej hmoo ntawm kev tsim cov cim ntawm cov kab mob lactic acidosis.
    • Los ntawm adrenomimetics txo cov nyhuv hypoglycemic.
    • Cov neeg txuas ntawm cov tshuaj insulin, sulfonylurea, acarbose thiab salicylate nce cov nyhuv hypoglycemic.
    • "Nifedipine" tsub kom ntau ntxiv kev nqus ntawm metformin.

    Cov lus qhia rau kev teem caij

    Cov tshuaj "Metformin Canon" yog tshaj tawm rau cov neeg mob ntshav qab zib muaj hom mob thib ob thaum muaj kev hloov kho hauv lub neej (noj cov zaub mov qis nrog rau kev ua kom lub cev txaus, kev tswj hauv lub xeev) tsis tau muaj kev tswj glycemic.

    Rau cov neeg mob nyhav dua, Metformin yog qhov kev xaiv zoo tshaj plaws. Cov tshuaj no tuaj yeem ua ke zoo nrog hypoglycemic tshuaj ntawm lwm pawg pharmacological, nyob rau hauv uas cov mechanism ntawm kev txiav txim txawv ntawm biguanides. Ua ke nrog kev kho mob insulin kuj tseem muaj peev xwm ua tau.

    Qhov tshuaj no tseem tau siv los kho tus mob ntshav qab zib hom II hauv cov menyuam yaus hnub nyoog ntau dua kaum xyoo. Nws yog siv los ua thawj-kab tshuaj ib zaug lossis hauv kev sib xyaw nrog insulin. Cov neeg tawm dag lub cev siv cov tshuaj no ua rau cov leeg qhuav, thiab cov menyuam ntxhais uas poob ceeb thawj yog sim, tab sis kev siv zoo li no tsuas yog siv thaum muaj teebmeem hnyav dhau los cuam tshuam nrog insulin tsis kam thiab ua rau lub cev tsis ua haujlwm.

    Sab sij huam

    Raws li cov lus qhia thiab tshuaj xyuas rau Metformin Canon, 850 mg, rau cov neeg laus thiab menyuam yaus, kev phiv los ntawm kev noj tshuaj yog tib yam. Muaj ib qho saj ntawm cov hlau nyob rau hauv lub qhov ncauj nrog rau kev ua rau lub plab zom mov ua qhov tsis txaus siab, tsis xeev siab, mob plab, mob raws plab thiab ntuav. Lub siab ua haujlwm qhov taw qhia yog ua txhaum, kab mob siab tshwm sim. Cov kev tsis haum tshuaj xws li B12 hypovitaminosis nrog rau kev ua xua (tawv nqaij ua pob khaus, ua pob xua, erythema, urticaria) rau cov tshuaj tsis tshua muaj.

    Noj ntau dhau

    Cov tshuaj no yuav tsum tau noj tsuas yog nyob rau hauv cov chaw tau hais tseg, txwv tsis pub nws yuav muaj kev pheej hmoo ntawm kev siv ntau dhau. Kev nqus ntawm Metformin, sib npaug rau 85 grams, tuaj yeem ua rau kev txhim kho ntawm cov kab mob lactic acidosis, uas yuav nrog cov leeg mob, thiab, ntxiv rau, tsis xis nyob hauv plab, xeev siab thiab ntuav. Yog tias qhov kev pabcuam tsis raug pabcuam raws sijhawm, ces kev siv tshuaj ntau dhau ntawm cov tshuaj no tuaj yeem ua rau kiv taub hau, tsis nco qab thiab tsis nco qab lawm tsis suav nrog. Tam sim no peb tig mus rau contraindications thiab pom thaum twg cov neeg mob yuav tsum tsis txhob noj cov tshuaj no rau kev kho mob.

    Cov yam ntxwv dav dav ntawm cov tshuaj

    Cov sib xyaw ua ke ntawm cov kab mob antidiabetic Metformin Canon suav nrog metformin hydrochloride, cov tshuaj zoo hauv ntiaj teb uas tuaj yeem txo cov piam thaj hauv ntshav qab zib.

    Ntxiv rau cov khoom tivthaiv no, cov kev npaj muaj ib qho me me ntawm sodium stearyl fumarate, hmoov txhuv nplej siab, titanium dioxide, talc, macrogol thiab lwm yam.

    Cov chaw tsim cov tshuaj hypoglycemic yog lub tuam txhab kev lag luam hauv tuam txhab Canonfarm ntau lawm.

    Lub tuam txhab ua tshuaj rau hauv daim ntawv ntawm cov ntsiav tshuaj (dawb, biconvex) hauv kev siv ntau yam:

    1. Metformin Canon 500 mg.
    2. Metformin Canon 850 mg.
    3. Metformin Canon 1000 mg.

    Cov tshuaj yog pub rau noj los ntawm lub hnub nyoog ntawm 10, tsis tsuas yog raws li kev kho mob monotherapy, tab sis kuj muaj kev sib xyaw nrog kev txhaj tshuaj insulin. Thaum noj, metformin yog nqus rau hauv cov hnyuv, thiab nws cov kev xav ntau tshaj yog tau kwv yees li 2-2.5 teev tom qab kev noj mov. Qhov kev txiav txim ntawm tus hypoglycemic yog qhia:

    • rau inhibit qhov tsim los ntawm cov piam thaj los ntawm tsis-carbohydrate sib txuas nyob rau hauv daim siab,
    • ua kom tsis muaj zog ntawm kev nqus ntawm cov piam thaj hauv cov hnyuv,
    • txhawm rau ua kom muaj kev cuam tshuam ntawm cov nqaij mos lub hom phiaj kom muaj suab thaj txo qis,
    • kom tshem tawm cov piam thaj ntawm cov nqaij mos,
    • mus txhawb rau intracellular glycogenesis,
    • ntawm kev ua haujlwm ntawm glycogen synthase,
    • kom ruaj khov lipid metabolism.

    Tsis tas li ntawd, cov tshuaj muaj qee cov nyhuv fibrinolytic. Metformin Canon muaj peev xwm ruaj khov thiab txo qhov hnyav lub cev. Nws txawv ntawm kev npaj ntawm sulfonylurea derivatives nyob rau hauv tias nws tsis ua rau muaj cov tshuaj insulin ntxiv thiab tsis ua rau cov piam thaj txo qis hauv cov neeg noj qab nyob zoo.

    Cov nquag tivthaiv kis tau sai sai hauv cov ntaub so ntswg. Nws tuaj yeem mus ua rau daim siab, qaub ncaug thiab lub raum.

    Metformin yog kev xyaum tsis tau metabolized, yog li nws raug tawm los ntawm lub raum hauv ib daim ntawv yuav luag tsis hloov.

    Cov lus qhia rau kev siv ntsiav tshuaj

    Txawm tias tom qab sab laj nrog koj tus kws kho mob tom qab yuav cov tshuaj, cov lus qhia rau kev siv yuav tsum tau ua tib zoo kawm. Yog tias koj muaj lus nug nrog tus neeg mob, koj yuav tsum nrhiav tus kws kho mob cov lus ntuas.

    Cov ntsiav tshuaj tau pom zoo kom siv thaum lub sijhawm lossis tom qab noj mov. Lawv tsis yog zom, tab sis nqos nrog ib khob dej. Cov lus piav qhia ntawm cov tshuaj hais tias thawj zaug tshuaj rau cov laus yog 1000-1500 mg ib hnub. Hauv qhov no, nws yog ntshaw kom faib cov koob tshuaj ntau zaug hauv ib hnub. Qhov kev pom zoo no yog vim qhov tseeb tias thaum lub sijhawm yoog lub cev mus rau qhov kev ua ntawm metformin, qee qhov kev mob tshwm sim, feem ntau cuam tshuam nrog kev zom cov txheej txheem. Tus mob ntshav qab zib tuaj yeem yws yws txog ntuav, raws plab, hloov pauv hauv qhov qab, mob plab, thiab flatulence. Txawm li cas los xij, tom qab 10-14 hnub, cov kev cuam tshuam no ploj mus ntawm lawv tus kheej.

    Tom qab lub cev tau siv tshuaj metformin, tus kws kho mob tuaj yeem nce cov tshuaj ntxiv ntawm cov neeg sawv cev hypoglycemic raws li tus neeg mob cov ntshav qab zib. Txoj kev saib xyuas txij nkawm tau txiav txim siab los ntawm 1500 txog 2000 mg rau ib hnub. Qhov pom zoo pub rau txhua hnub yog 3000 mg.

    Yog tias tus neeg mob hloov mus rau Metformin Canon nrog lwm cov kev tawm tsam, nws yuav tsum tsum tsis txhob noj lub tom kawg. Thaum muab cov tshuaj sib xyaw nrog cov tshuaj insulin, nws raug nquahu thaum pib kho kom noj 500 lossis 850 mg ob rau peb zaug ib hnub. Metformin 1000 mg tau noj ib hnub ib zaug.

    Cov menyuam yaus uas muaj hnub nyoog txog 10 xyoo tuaj yeem pib kho nrog 500 mg ntawm yeeb tshuaj. Nws raug nquahu kom noj hmo thaum noj mov. Tom qab 10-14 hnub, tus kws kho mob tuaj yeem nce cov tshuaj rau txhua hnub rau 1000-1500 mg. Tso cai rau tus menyuam noj tsis pub ntau tshaj 2000 mg rau ib hnub.

    Cov neeg mob ntshav qab zib tsim nyog yuav tsum tau tshwj xeeb. Dosages thiab sijhawm ntawm kev kho mob yog xaiv los ntawm tus kws kho mob tshwj xeeb. Hla lub hnub nyoog 60 xyoo, ib qho yeeb tshuaj hypoglycemic tuaj yeem ua rau lub raum ua haujlwm.

    Nws yuav tsum nco ntsoov tias cov tshuaj tsis tuaj yeem yuav tsis tau yog tsis muaj kws kho mob sau ntawv. Txoj kev ntim cov Metformin Canon yuav tsum ceev cia kom tsis txhob ncav lub hnub thiab cua sov. Cia qhov kub thiab txias yuav tsum tsis tshaj 25 degrees Celsius.

    Tom qab hnub tas sij hawm, uas yog 2 xyoos, kev tswj hwm ntawm ib tus neeg sawv cev rau kev tiv thaiv tsis zoo.

    Lwm cov tshuaj sib cuam tshuam

    Raws li koj paub, qee cov tshuaj tuaj yeem ua rau muaj kev cuam tshuam ncaj qha rau kev ua ntawm Metformin Canon, txo lossis nce nws cov nyhuv hypoglycemic.

    Cov lus qhia tau hais tias kev sib xyaw ua ke yog kev siv ntawm iodine-muaj cov khoom sib xws.

    Tawm tsam keeb kwm yav dhau los ntawm lub raum tsis ua haujlwm hauv cov neeg mob, lawv tuaj yeem ua rau kev txhim kho ntawm cov kab mob lactic acidosis. Nws kuj tsis pom zoo kom sib xyaw ua ke haus cawv, lub voj diuretics thiab kev npaj uas muaj ethanol nrog kev siv cov metformin.

    Qhov kev tshwj xeeb tshwj xeeb yog qhov yuav tsum tau los ntawm cov tshuaj uas tuaj yeem ua rau qaug zog ntawm kev ua cov tshuaj metformin thiab ua rau hyperglycemia. Cov no suav nrog:

    1. Danazole
    2. Chlorpromazine.
    3. Cov tshuaj tiv thaiv.
    4. Glucocortecosteroids.
    5. Beta2-adrenergic agonists.

    Angiotensin-hloov enzyme inhibitors, insulin txhaj tshuaj, salicylates, acarbose thiab sulfonylureas derivatives tuaj yeem txhim kho cov nyhuv hypoglycemic ntawm metformin.

    Nws yuav tsum raug coj mus rau hauv tus account tias nrog kev tswj hwm nifedipine thiab metformin tib lub sijhawm, kev mob ntshav qab zib tsawg yuav tshwm sim mob ntshav qab zib mellitus. Txhawm rau tiv thaiv kev txhim kho lub raum tsis ua haujlwm, nws yog qhov yuav tsum tau siv NSAIDs nrog ceev faj.

    Nyob rau hauv txhua rooj plaub, thaum txiav txim siab yuav siv cov tshuaj twg, ua ntej ntawm txhua yam, nws yog qhov yuav tsum tau sab laj nrog koj tus kws kho mob. Kev zais ntawm cov pathologies los ntawm kws kho mob tuaj yeem ua rau tsis muaj qhov cuam tshuam.

    Tus nqi thiab tshuaj tshuaj

    Txhua tus neeg mob tau muaj txoj hauv kev los yuav cov tshuaj no hauv cov khw muag tshuaj lossis sau ib daim ntawv thov rau kev yuav khoom hauv khw muag khoom lub vev xaib.

    Ib tus neeg tuaj yeem yuav tsom tsis tsuas yog kho cov nyhuv tshuaj, tab sis kuj ntawm nws tus nqi. Nws yuav tsum raug sau tseg tias Metformin Canon muaj tus nqi tsawg.

    Yog li, txhua tus neeg mob tuaj yeem tuaj yeem yuav ib lub tshuaj.

    Nws tus nqi yog nyob ntawm daim ntawv tso tawm thiab cov naj npawb ntawm cov ntsiav tshuaj hauv pob:

    • Metformin Canon 500 mg (30 ntsiav tshuaj) - los ntawm 94 txog 110 rubles,
    • Metformin Canon 850 mg (30 ntsiav tshuaj) - 112 txog 116 rab phom,
    • Metformin Canon 1000 mg (30 ntsiav tshuaj) - los ntawm 117 txog 165 rubles.

    Ntawm cov kws kho mob thiab cov neeg mob, koj tuaj yeem pom ntau cov lus zoo hais txog kev siv cov tshuaj no. Yog li, cov ntshav qab zib tau ceeb toom tias Metformin Canon tswj cov qib ntshav qabzib tsis tas ua rau cov ntshav qab zib. Kev txheeb xyuas tseem qhia tau poob phaus ntawm cov neeg rog. Yog li, ntawm qhov zoo ntawm cov tshuaj tuaj yeem txheeb xyuas kev ua tau zoo, yooj yim siv thiab tus nqi qis.

    Qhov tsis zoo ntawm kev siv cov tshuaj no suav hais tias yog kev phiv tshuaj uas tshwm sim nyob rau hauv teb rau kev nqis tes ua ntawm metformin - ua kom mob plab. Tab sis thaum faib cov tshuaj txhua hnub rau hauv ob peb koob tshuaj, cov tsos mob zoo li txo tau.

    Feem ntau ntawm cov neeg mob uas tau noj Metformin Canon dua ib zaug rov qab hais tias kev kho nrog cov tshuaj yog "nullified" yog tias koj tsis ua raws li kev noj zaub mov noj, tsis koom nrog kev ua kis las thiab tsis tswj kev ua kom muaj suab thaj txhua hnub.

    Cov tshuaj zoo sib xws

    Qee zaum kev siv cov tshuaj yuav dhau los tsis yooj yim rau ntau yam laj thawj, seb nws yog contraindications los yog kev phiv tshuaj.

    Hauv cov xwm txheej zoo li no, txhua lub luag haujlwm yog nyob nrog tus kws kho mob, uas txiav txim siab hloov cov tshuaj. Nyob rau tib lub sijhawm, nws yuav tsum coj mus rau hauv tus neeg mob cov ntshav qab zib thiab nws kev noj qab haus huv.

    Cov tshuaj zoo sib xws muaj cov nyhuv tshuaj zoo sib xws, tab sis txawv hauv lawv muaj pes tsawg leeg.

    Metformin yog ib hom tshuaj uas nrov heev uas siv los ua kom cov ntshav qabzib ntau. Hauv qhov hais txog no, nws raug siv los ua cov haujlwm tseem ceeb ntawm ntau tus neeg sawv cev hypoglycemic.

    Ntawm cov analogues paub ntawm Metformin Canon paub qhov txawv:

    1. Gliformin yog cov tshuaj tiv thaiv kev ua kom zoo uas siv rau kev tsis haum ntawm sulfonylureas. Ua tsaug rau cov metformin uas muaj, nws pab txo kom yuag hauv cov neeg rog. Nws cov nqi nruab nrab yog nyob ntawm daim ntawv tso tawm: 500 mg -106 rubles, 850 mg -186 thiab 1000 mg - 368 rubles.
    2. Glucophage yog lwm qhov kev kho mob uas zwm rau hauv cov pab pawg biguanide. Nws tshwm sim nyob rau hauv daim ntawv ntawm kev ncua ntev (Glucophage Ntev). Nws kuj tseem siv kho mob ntshav qab zib insulin. Tus nqi nruab nrab ntawm ib pob nyob ntawm 107 txog 315 rubles.
    3. Siofor 1000 yog ib hom tshuaj siv los tiv thaiv thiab kho ntshav qab zib, nrog rau poob phaus. Qhov nruab nrab, tus nqi nws txawv ntawm 246 txog 420 rubles, yog li nws tsis tuaj yeem hu ua tus qauv pheej yig heev.
    4. Metformin-Teva yog ib cov tshuaj uas siv rau ntshav qab zib hom 2, thaum kev noj haus thiab kev tawm dag zog tsis muaj zog. Ib yam li Metformin Canon, nws ua rau glycemia, lipid metabolism thiab lub cev hnyav ntawm tus neeg mob. Tus nqi nruab nrab ntawm cov tshuaj yog los ntawm 125 txog 260 rubles.

    Muaj ntau lwm yam tshuaj uas muaj cov nyhuv zoo ntawm Metformin Canon. Cov ncauj lus kom ntxaws txog lawv tuaj yeem nrhiav siv Is Taws Nem lossis nug koj tus kws kho mob.

    Metformin Canon yog tshuaj zoo tiv thaiv kab mob. Nrog rau kev siv kom zoo, koj tuaj yeem tshem tawm cov tsos mob ntawm "tus kab mob qab zib" thiab nyob nrog cov neeg muaj mob noj qab haus huv. Txawm li cas los xij, thaum lub sijhawm siv cov tshuaj, koj yuav tsum ua raws li txhua tus lus qhia ntawm tus kws kho mob, thiaj li tsis ua rau koj tus kheej raug mob.

    Tus kws tshaj lij los ntawm daim vis dis aus hauv tsab xov xwm no yuav tham txog Metformin.

    Dab tsi yog Metformin

    Cov thawj coj hauv txoj kev kho mob hom 2 mob ntshav qab zib mellitus coj Metformin. Nws zwm rau lub biguanides. Cov no yog cov tshuaj uas txo cov ntshav piam thaj. Qhov ua tau zoo ntawm cov tshuaj tau raug pov thawj los ntawm lub sijhawm, kev coj ua ntawm kev siv, raws li muaj pov thawj los ntawm kev tshuaj xyuas tus neeg mob. Nov yog tib cov tshuaj siv los kho ntshav qab zib hauv menyuam yaus. Metformin muaj ntau lub npe, nws raug muag xws li Glucofage, Siofor, Gliformin. Nws nyob ntawm qhov chaw tsim khoom thiab cov lus sib xyaw ntawm cov tshuaj.

    Kev Sib Sau thiab daim ntawv ntawm kev tso tawm

    Metformin muaj nyob hauv daim ntawv foos. Lawv yog cov puag ncig, biconvex, them nrog ib qho ntxig qe plooj ntawm cov xim dawb. Cov tshuaj tau ntim rau hauv cov hlwv 10 lossis 15 daim. Kev ntim khoom muag yuav tuav 30 ntsiav tshuaj. Lub rooj qhia cov khoom sib xyaw ntawm ib cov tshuaj ntsiav:

    Kev siv tshuaj nquag

    Metformin hydrochloride (lossis dimethylbiguanide)

    Hmoov txhuv pob kws (lossis qos)

    Yuav noj li cas

    Cov ntsiav tshuaj tau nqos tag nrho, ntxuav nrog dej kom ntau. Qhov koob tshuaj tsawg kawg nkaus yog 500 mg ib hnub ib zaug, qhov siab tshaj plaws yog 2.5-3 g. Nws raug nquahu kom noj cov tshuaj metformin tom qab noj hmo lossis tam sim ua ntej mus pw. Qhov ntau ntawm cov tshuaj yog zoo dua rau cov neeg nce zuj zus. Qhov pib loj ntawm dimethylbiguanide ua rau lub plab ua haujlwm thiab cuam tshuam ntawm kev zom zaub mov. Nws yog xim hlau saj, xeev siab yog cov cim ntawm kev overdose hauv thawj theem ntawm kev siv cov khoom lag luam kws tshuaj.

    Nrog rau cov tshuaj tua kab mob nrog cov tshuaj, nws zoo dua rau kev ua raws li cov txheej txheem ua pov thawj:

    1. Hauv thawj lub lis piam, cov tshuaj hauv qhov ntau npaum li 500 mg yog noj 1 zaug.
    2. Tom ntej, kev noj tshuaj txhua hnub yog nce mus rau 850-1000 mg thiab muab faib ua 2 koob tshuaj.
    3. Yog tias cov txheej txheem metabolic tsis txaus siab ntawm qhov ntau kawg 2000 mg, sulfonylureas yuav tsum ntxiv rau metformin lossis insulin yuav tsum tau siv.
    4. Txoj kev nce ntxiv hauv cov tshuaj yog nyob ntawm cov piam thaj. Kev noj tshuaj ntau dua yog xaiv los ntawm tus kws kho mob.
    5. Hauv cov neeg mob laus, qhov tshuaj ntau tshaj txhua hnub yog 1000 mg.

    Cia thiab muag cov neeg mob

    Cov tshuaj no tsuas yog tso tawm los ntawm lub hwj tshuaj. Lub txee lub neej ntawm cov khoom no yog ob xyoos, tom kawg uas tau txwv tsis pub siv cov tshuaj no. Cov tshuaj yuav tsum tau muab cia rau hauv qhov chaw tiv thaiv los ntawm lub teeb, uas yuav tsum tau qhuav, ntawm qhov kub tsis tshaj li nees nkaum degrees.

    Tus nqi ntawm 60 ntsiav tshuaj ntawm "Metformin Canon" 850 mg - txog 200 rubles.

    Tom ntej no, peb pom zoo li cas tib neeg sau txog cov tshuaj no, thiab ntxiv rau, peb yuav tau paub txog kev xav ntawm cov kws kho mob txog kev ua tau zoo ntawm cov tshuaj hauv cov lus nug.

    Ua ntej, xav txog kev tshuaj xyuas txog "Metformin Canon" 850 mg los ntawm cov neeg mob.

    Cov Lus Lus Tus Neeg Mob

    Hauv kev txheeb xyuas, cov neeg mob paub meej txog kev ua haujlwm ntawm cov tshuaj hauv cov lus nug yog ib feem ntawm kev kho ntshav qab zib thiab raws li txhais tau tias yuav poob phaus yam tsis xav tau.Raws li cov neeg siv tshuaj xyuas, Metformin Canon yog qhov tshuaj pheej yig thiab siv tau txiaj ntsig, feem ntau yog hais txog kev tswj ntshav qabzib, thiab lub cev qhov hnyav. Ntawm cov kev cuam tshuam tseem ceeb, cov tsos pom ntawm kev phiv los ntawm cov hnyuv feem ntau tau hais txog.

    Cov kws kho mob tshuaj xyuas

    Hauv lawv kev tshuaj xyuas ntawm "Metformin Canon" 850 mg, cov kws tshaj lij kuj lees paub cov peev xwm ntawm cov tshuaj no. Tab sis lawv ceeb toom hais tias thaum lub sij hawm kho yuav tsum tau saib xyuas cov kua nplaum kom zoo.

    Nws yog qhov zoo dua los paub koj tus kheej nrog kev tshuaj xyuas ntawm cov kws kho mob txog Metformin Canon ua ntej.

    Cov kws kho mob sau tias thaum noj cov tshuaj no, mob hnyav, ua rau lub cev tsis muaj zog, mob hauv cov leeg lossis mob plab nrog rau ntuav tuaj yeem tshwm sim. Hauv txhua qhov xwm txheej no, cov neeg mob yuav tsum sab laj nrog kws kho mob, vim tias cov tsos mob zoo li no yuav qhia txog kev txhim kho ntawm cov kab mob lactic acidosis.

    Tsis tas li, cov kws kho mob hauv kev tshuaj xyuas ntawm Metformin Canon qhia ceeb toom rau qee qhov kev ua tsis taus lub raum, piv txwv li, thaum pib ntawm txoj kev kho nrog kev siv tshuaj uas tsis yog tshuaj steroid. Cov kws kho mob tshwj xeeb pom zoo rau cov neeg mob nrog kws kho mob tawm tsam keeb kwm ntawm kev nthuav dav ntawm kev ua kom muaj kab mob sib kis ntawm cov kab mob genitourinary lossis kab mob ntsws.

    Metformin Ntev Canon

    Cov tshuaj no ua rau lub ntsej muag hypoglycemic los ntawm qeb ntawm biguanides. Tus txheej txheem ntawm kev ua yog txuam nrog lub peev xwm ntawm cov tshuaj los txo cov gluconeogenesis nrog rau kev tsim ntawm cov roj dawb. Cov tshuaj tsub ntxiv rau peripheral receptor insulin rhiab heev. Nws yog tsim nyog sau cia tias Metformin Ntev Canon tsis cuam tshuam rau qhov tshuaj insulin hauv cov ntshav, tab sis hloov nws cov chaw muag tshuaj.

    Cov tshuaj stimulates glycogen synthesis. Thauj khoom muaj peev xwm ntawm txhua hom membrane hom khoom thauj thauj nce. Cov tshuaj, nrog rau lwm yam, ncua kev nqus ntawm cov piam thaj hauv cov hnyuv, txo qis ntawm triglycerides, thiab tseem txhim kho cov khoom muaj ntshav fibrinolytic. Tawm tsam cov keeb kwm yav dhau los ntawm kev siv cov tshuaj no, tus neeg mob lub cev qhov hnyav tseem nyob ruaj khov lossis yuav txo qis.

    Kev taw qhia rau kev siv tshuaj ncua sijhawm

    Qhov tseem ceeb tshaj plaws yog hom 2 mob ntshav qab zib rau cov neeg laus (tshwj xeeb yog cov neeg mob rog rog), yog tias kev tawm dag zog thiab kev tawm dag zog tsis muaj txiaj ntsig. Hauv cov xwm txheej no, cov tshuaj tau sau tawm yog ib feem ntawm kev kho mob monotherapy thiab hauv kev sib xyaw nrog lwm tus neeg lub cev qhov ncauj ntshav lossis tshuaj insulin.

    Txoj kev ntawm kev coj thiab ntau npaum li cas ntawm kev noj tshuaj ntev

    Cov tshuaj no yuav tsum tau noj los ntawm cov neeg mob sab hauv. Cov ntsiav tshuaj tau nqos, tsis tau zom thiab ntxuav nrog qhov muaj kua txaus. Lawv tuaj yeem tuaj yeem haus cawv ib zaug tom qab lossis thaum noj hmo. Tus kws kho mob xaiv cov tshuaj ntawm cov tshuaj ib lub zuj zus rau ib tus neeg mob tshwj xeeb raws li cov txiaj ntsig cov piam thaj hauv kev ntsuas.

    Rau cov neeg mob uas tsis tau noj dua yav dhau los metformin, kev pom zoo pom zoo thawj zaug ntawm cov tshuaj no yog 500 milligrams ib hnub ib zaug tom qab noj hmo. Txhua kaum lossis kaum tsib hnub, nws raug nquahu kom kho cov tshuaj ntau npaum li cas los ntawm kev ntsuas ntsuas cov piam thaj hauv ntshav ntshav. Kev ua kom tau qeeb qeeb me me ua rau muaj qhov kam rau ua zoo dua rau ntawm cov zom zaub mov.

    Yog li, cov tshuaj Metformin Canon, suav tias nyob hauv tsab xov xwm, tau tsim rau kev kho mob ntshav qab zib hom 2 hauv cov neeg laus. Tab sis, raws li twb tau sau tseg ntau zaus, thaum lub sijhawm no nws nce mus rau qhov ntau ntawm lub luag hauj lwm ntawm txhais tau tias kom ua tiav phaus nrawm nrawm thiab qee zaum txawm tias raug xaiv los ntawm cov neeg raws li cov neeg noj zaub mov.

    Peb tau soj ntsuam cov lus qhia rau "Metformin Canon" 850 mg.

    Pharmacological kev txiav txim

    Kev Siv Tshuaj Metformin yog ib qho kev tiv thaiv hypoglycemic uas cuam tshuam txog biguanides thiab sib sau ua ke hauv lub siab, ua haujlwm rau cov qaub ncaug, thiab lub raum. Qhov ua tau zoo ntawm cov tshuaj cuam tshuam nrog kev muaj peev xwm inhibit gluconeogenesis, kev tsim cov roj dawb dawb thiab ua rau oxidation ntawm cov roguas cuam tshuam pharmacological zoo ntawm cov tshuaj:

    • piam thaj txo
    • kev nkag siab zoo ntawm cov tshuaj insulin, txhim kho kev nqus suab thaj, ua kom muaj roj oxidation thiab peripheral qabzib siv,
    • txo qis kev nqus ntawm cov piam thaj ntawm lub plab zom mov, cov thyroid-stimulating hormone ntawm cov ntshav,
    • tej roj uas txhaws taus, triglycerides thiab lipoproteins tsawg ceev,
    • normalization ntawm ntshav coagulability, txhim kho nws cov rheological zog, uas txo txoj kev pheej hmoo ntawm thrombosis,
    • poob phaus hauv kev kho mob rog.

    Thov

    Metformin yog tshuaj rau cov neeg mob ntshav qab zib hom 2 mellitus (tsis yog mob insulin). Kev kho nrog cov tshuaj yog pom zoo yog tias tus neeg mob tau mob los ntawm kev rog rog concomitant los yog, yog tias tsim nyog, soj ntsuam cov ntshav qab zib kom muaj nuj nqisCov. Cov tshuaj yog kws kho mob kho raws li monotherapy lossis cov tshuaj ntxiv rau insulin lossis lwm yam tshuaj tiv thaiv ntshav qab zib.

    Tsuas tshuaj thiab tswj hwm

    Cov tshuaj yog noj ntawm qhov ncauj thaum noj mov lossis tom qab kiag. Cov ntsiav tshuaj yuav tsum tau nqos tag nrho yam tsis ntxo. Qhov ntau thiab tsawg zaus ntawm Metformin nyob ntawm seb hom kev kho mob twg:

    Cov neeg laus Metformin monotherapy thiab kev kho mob sib xyaw nrog lwm cov tshuaj hypoglycemic hauv qhov ncauj

    1000-1500 mg / hnub. - thawj zaug koob tshuaj. Nws ua tau kom txo cov kev phiv los ntawm txoj hnyuv plab hnyuv (lub plab zom mov) los ntawm kev faib kom tsawg los ntawm 2-3 zaug. Thaum tsis muaj qhov tsis zoo tshwm sim ntawm txoj hnyuv, tom qab 10-15 hnub, cov koob tshuaj tuaj yeem raug maj mam nce ntxiv (nyob ntawm cov piam thaj).

    Txij nkawm noj txhua hnub ntau npaum - 1500-2000 mg. Qhov siab ntau tshaj plaws ib hnub - 3000 mg, faib ua 3 koob.

    Hloov ntawm lwm cov tshuaj noj hauv qhov ncauj mus rau cov tshuaj ntshav qab zib Metformin

    Pib noj cov tshuaj (cov koob tshuaj saum toj no) tom qab txiav kev siv lwm yam tshuaj hypoglycemic.

    Kev sib xyaw ua ke nrog cov tshuaj insulin

    Nrog rau thawj koob tshuaj 500 mg thiab 850 mg, noj ib ntsiav tshuaj 2-3 zaug / hnub., Thaum 1000 mg - 1 ntsiav tshuaj 1 zaug / hnub. Qhov ntau npaum li cas ntawm cov kua dej yog xaiv raws li cov piam thaj nyeem.

    Cov menyuam yaus hnub nyoog 10 txog 16 xyoo. Cov tshuaj yog siv rau kev kho mob monotherapy thiab hauv kev kho mob sib xyaw nrog insulin.

    Thawj qhov tshuaj yog 500 mg 1 zaug nyob rau ib hnub, noj thaum yav tsaus ntuj nrog zaub mov noj. Tom qab 10-15 hnub, feem tau muab kho raws li cov piam thaj muaj nuj nqis. 1000-1500 mg / hnub., Muab faib los ntawm 2-3 zaug - ib koob tshuaj txij nkawm. 2000 mg hauv 3 koob tshuaj faib - ntau kawg.

    Cov neeg hauv lub hnub nyoog laus

    Cov koob tshuaj yog xaiv raws li kev soj ntsuam ib txwm ntawm lub raum kev ua haujlwm (tsawg kawg 2-4 zaug hauv ib xyoos).
    Tus kws kho mob txiav txim siab lub sijhawm kho.

    Cia Koj Saib

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