Cov lus qhia rau kev siv "Lantus Solostar": cov lus muaj pes tsawg leeg, cov qauv analogues, cov nqi thiab cov neeg siv khoom tshuaj xyuas

Lantus yog ib qho ntawm thawj qhov tsis muaj kab zauv ntawm tib neeg cov tshuaj insulin. Tau los ntawm kev hloov cov amino acid asparagine nrog glycine ntawm txoj hauj lwm 21st ntawm txoj saw A thiab ntxiv ob lub arginine amino acids hauv cov saw B mus rau qhov kawg amino acid. Cov tshuaj no yog tsim los ntawm kev lag luam tshuaj Fabkis loj - Sanofi-Aventis. Hauv qhov kev tshawb fawb ntau, nws tau ua pov thawj tias insulin Lantus tsis tsuas yog txo cov kev mob ntshav qab zib tsawg dua piv nrog cov tshuaj NPH, tab sis tseem txhim kho cov metabolism hauv metabolism. Hauv qab no yog cov lus qhia luv luv rau kev siv thiab tshuaj xyuas cov neeg mob ntshav qab zib.

Kev cuam tshuam nrog lwm yam tshuaj

Muaj cov tshuaj uas cuam tshuam rau cov metabolism hauv cov metabolism, thaum nce los yog txo qis yuav tsum muaj cov insulin.

Txo cov piam thaj: cov tshuaj tiv thaiv kab mob hauv lub cev, sulfonamides, ACE inhibitors, salicylates, angioprotectors, monoamine oxidase inhibitors, antiarrhythmic dysopyramides, narcotic analgesics.

Qab zib kom ntau: cov thyroid hormones, diuretics, sympathomimetics, tshuaj tiv thaiv hauv lub qhov ncauj, phenothiazine derivatives, protease inhibitors.

Qee yam tshuaj muaj ob qho ua kom tsis pom kev thiab qhov ua tsis zoo. Cov no suav nrog:

• beta blockers thiab ntsev lithium,
• cawv
• clonidine (antihypertensive tshuaj).

Cov Yuav Tsum Tau Ua

1. Nws yog txwv tsis pub siv rau hauv cov neeg mob uas tsis nkag siab rau insulin glargine lossis ntu sib xyaw.
2. Kev ntshav siab.
3. Kev kho mob ntawm cov ntshav qab zib ketoacidosis.
4. Cov me nyuam qis dua 2 xyoos.

Ua tau qhov tsis zoo tshwm sim tsawg tsawg, cov lus qhia tau hais tias tej zaum yuav muaj:

• lipoatrophy los yog lipohypertrophy,
• kev ua xua (Quincke's edema, kev tsis haum, tshuaj bronchospasm),
• mob nqaij thiab mob qeeb hauv lub cev ntawm sodium ions,
• mob plab thiab qhov muag tsis pom kev.

Kev Hloov mus rau Lantus los ntawm lwm yam insulin

Yog hais tias tus mob ntshav qab zib tau siv cov tshuaj insulins nyob rau ncua sijhawm, tom qab ntawd thaum hloov mus rau Lantus, kev noj ntau dua thiab kev noj tshuaj hloov pauv. Kev hloov pauv cov kua dej yuav tsum tau nqa tawm hauv tsev kho mob nkaus xwb.

Hauv lub neej yav tom ntej, tus kws kho mob saib cov piam thaj, tus neeg mob lub neej, qhov hnyav thiab kho rau ntau pawg uas tau tswj hwm. Tom qab peb lub hlis, cov hauj lwm zoo ntawm cov tshuaj kho tau tuaj yeem tshawb xyuas los ntawm kev soj ntsuam ntawm glycated hemoglobin.

Kev qhia video:

Zaj dab neeg ntawm ib qho ntawm peb cov neeg nyeem, Inga Eremina:

Kuv qhov hnyav tau tshwj xeeb tshaj yog kev nyuab siab, Kuv hnyav ib yam li 3 tus lej wrestlers ua ke, uas yog 92kg.

Yuav ua li cas tshem tawm qhov hnyav tshaj kom tiav? Yuav daws cov tshuaj hormonal hloov thiab rog dhau li cas? Tab sis tsis muaj dab tsi yog li disfiguring lossis hluas rau ib tus neeg li nws daim duab.

Tab sis yuav ua li cas thiaj poob ceeb thawj? Laser liposuction phais? Kuv pom - tsawg kawg 5 txhiab daus las. Cov txheej txheem kho vajtse - LPG zaws, cavitation, RF nqa, myostimulation? Ib nyuag pheej yig dua - cov nqi kawm ntawm 80 txhiab rubles nrog kws tshaj lij kws paub txog khoom noj khoom haus. Koj muaj peev xwm tiv thaiv sim khiav ntawm lub cos, mus rau qhov tsis pom kev.

Thiab thaum twg kom nrhiav tau txhua lub sijhawm no? Yog thiab tseem kim heev. Tshwj xeeb tam sim no. Yog li ntawd, rau kuv tus kheej, Kuv xaiv txoj kev sib txawv.

Hauv tebchaws Lavxias, txhua tus mob ntshav qab zib insulin-tau raug tshem tawm ntawm Lantus mus rau Tujeo. Raws li kev tshawb nrhiav, cov tshuaj tshiab muaj qhov txo qis ntawm cov mob ntshav qab zib tsawg, tab sis hauv kev xyaum feem ntau cov neeg yws tias tom qab hloov mus rau Tujeo lawv cov piam thaj tau dhia tau siab, yog li lawv raug yuam yuav Lantus Solostar insulin ntawm lawv tus kheej.

Levemir yog cov tshuaj zoo heev, tab sis nws muaj cov tshuaj sib txawv, txawm tias lub sijhawm ua haujlwm kuj yog 24 teev.

Aylar tsis ntsib insulin, cov lus qhia hais tias qhov no yog tib qho Lantus, tab sis cov chaw tsim khoom pheej pheej yig dua.

Insulin Lantus thaum cev xeeb tub

Cov kev tshawb fawb soj ntsuam ntawm Lantus nrog cov poj niam cev xeeb tub tsis tau ua. Raws li cov ntaub ntawv tsis raug cai, cov tshuaj tsis cuam tshuam loj heev hauv chav kawm ntawm cev xeeb tub thiab tus menyuam nws tus kheej.

Cov kev sim tau nrhiav rau ntawm cov tsiaj, thaum lub sijhawm nws tau ua pov thawj tias insulin glargine tsis muaj qhov phiv rau ntawm kev ua me nyuam.

Cev xeeb tub Lantus Solostar tuaj yeem siv tshuaj yog tias tsis muaj zog tiv thaiv NPH. Cov niam yav tom ntej yuav tsum saib xyuas lawv cov suab thaj, vim tias nyob rau thawj peb lub hlis, xav tau cov tshuaj insulin tuaj yeem txo qis, thiab hauv lub hlis thib ob thiab peb lub hlis.

Tsis txhob ntshai tsam pub niam mis rau tus menyuam noj, cov lus qhia tsis muaj cov ntaub ntawv uas Lantus tuaj yeem nkag mus rau niam mis tau.

Lub txee lub neej ntawm Lantus yog 3 xyoos. Koj yuav tsum muab cia rau hauv qhov chaw tsaus tiv thaiv los ntawm tshav ntuj ntawm qhov kub ntawm 2 txog 8 degrees. Feem ntau qhov chaw zoo tshaj plaws yog tub yees. Hauv qhov no, nco ntsoov saib cov txheej txheem kub, vim tias qhov txias khov ntawm cov tshuaj insulin Lantus yog txwv!

Txij li thaum siv thawj zaug, cov tshuaj yuav khaws cia rau ib hlis nyob rau hauv qhov chaw tsaus ntawm qhov kub ntawm tsis ntau tshaj 25 degrees (tsis nyob hauv tub yees). Tsis txhob siv cov tshuaj insulin uas tas sijhawm.

Qhov yuav yuav, nqe

Lantus Solostar yog tshuaj dawb los ntawm kev kho mob los ntawm kev kho mob endocrinologist. Tab sis nws tseem tshwm sim uas tus mob ntshav qab zib yuav tsum yuav cov tshuaj no ntawm nws tus kheej ntawm lub tsev muag tshuaj. Tus nqi nruab nrab ntawm cov tshuaj insulin yog 3300 rubles. Hauv Ukraine, Lantus tuaj yeem yuav rau 1200 UAH.

Tus kws kho ntshav qab zib hais tias nws yog ib qho zoo heev insulin, hais tias lawv qab zib yog khaws cia nyob rau hauv ib txwm txwv. Ntawm no yog cov neeg yuav hais dab tsi txog Lantus:

Feem ntau sab laug tsuas yog cov tshuaj xyuas qhov zoo. Ob peb cov neeg hais tias Levemir lossis Tresiba zoo dua rau lawv.

Tshuav Daim Duab Solostar

Lantus solostar 100ed / ml 3ml 5 pcs. daws rau subcutaneous tswj hwm ntawm lub cartridge. hauv sp.-kov.

Sanofi (Russia) Kev Npaj: Lantus solostar

Cov tshuaj los ntawm pawg Insulin

Actrapid nm 100 u / ml 10 ml txhaj

Novo Nordisk A / C (Denmark) Kev Npaj: Actrapid nm

Qib Qeb 100me / ml 3ml 5 pcs. kev daws rau cov leeg thiab subcutaneous ntawm tus cartridge

Eli Lilly East S.A. (Fabkis) Npaj: Humalog

Biosulin n 100me / ml 3ml 5 pcs. raug muab tshem tawm rau kev coj mus rau subcutaneous ntawm cartridges. hauv sp.-kov.

Pharmstandard Rx (Russia) Kev Npaj: Biosulin n

Levemir flekspen 100ed / ml 3ml 5 pcs. rr-p rau subcutaneous kev tswj hwm ntawm daim cartridges. hauv sp.-kov.

Novo Nordisk A / C (Denmark) Kev Npaj: Levemir flekspen

Kev ntsuas los ntawm qeb ntshav qab zib

5 mg maninil 120 pcs. ntsiav tshuaj

Berlin Chemie (Lub Tebchaws Yelemees) Kev Npaj: Maninil

Gliformin 1000mg 60 pcs. zaj duab xis-ntsiav tshuaj ntsiav tshuaj

Akrikhin (Russia) Kev Npaj: Gliformin

Glurenorm 30mg 60 pcs. ntsiav tshuaj

Beringer Ingelheim Pharma (Lub Tebchaws Yelemees) Kev Npaj: Glurenorm

Siofor 500mg 60 pcs. txheej ntsiav tshuaj

Berlin Chemie (Lub Tebchaws Yelemees) Kev Npaj: Siofor 500

Siofor 850mg 60 pcs. txheej ntsiav tshuaj

Berlin Chemie (Lub Tebchaws Yelemees) Kev Npaj: Siofor 850

Tso tawm daim ntawv, muaj pes tsawg leeg thiab ntim khoom

Kev daws rau sc tswj hwm yog pob tshab, xim tsis muaj xim lossis yuav luag tsis muaj xim.

Cov zam: metacresol (m-cresol) - 2.7 mg, zinc chloride - 0.0626 mg (sib xyaw rau 30 μg zinc), glycerol (85%) - 20 mg, sodium hydroxide - txog pH 4.0, hydrochloric acid - txog pH 4.0, dej d / thiab - txog li 1 ml.

3 ml - daim cartridges los ntawm pob tshab, tsis muaj kob (iav I), teeb tsa hauv SoloStar cov ntawv txhaj tshuaj (5) - pob ntawm cov duab los qhia nrog daim npav.

Pharmacological kev txiav txim

COV DABNEEG HNUB QUB KAWG!

Cov tshuaj nquag ntawm Lantus yog cov tshuaj insulin glargine. Nws kis tau los ntawm kev rov ua dua caj ces siv k-12 leeg kab ntawm cov kab mob Escherichia coli. Hauv qhov nruab nrab nruab nrab, nws yog me ntsis soluble, nyob rau hauv nruab nrab acidic nws yaj nrog kev tsim ntawm microprecipitate, uas tas li thiab maj mam tso cov kua dej. Vim tias qhov no, Lantus tau muaj ib cov profile ua haujlwm ntev txog 24 teev.

Zaj dab neeg ntawm ib qho ntawm peb cov neeg nyeem Alina R.:

Nyiaj txiag tau ib txwm ua kuv qhov kev txhawj xeeb tseem ceeb. Vim li no, Kuv muaj cov pawg ntawm cov complexes. Kuv xav tias kuv tus kheej tsis ua tiav, teeb meem tom haujlwm thiab hauv kuv lub neej. Txawm li cas los xij, Kuv txiav txim siab tias kuv tseem xav tau kev pabcuam ntawm kuv tus kheej. Qee lub sij hawm nws zoo nkaus li qhov teeb meem nyob hauv koj tus kheej, txhua qhov kev ua tiav tsuas yog kev rau txim ntawm lub zog tsis zoo, qhov muag tsis zoo, lossis lwm yam kev quab yuam.

Nws yog qhov nyuaj ua kev zoo siab ua haujlwm ua tus khaws nyiaj rau 26t.r. thaum koj yuav tsum them 11 txhiab rau chav tsev xauj. Dab tsi ua rau kuv xav tsis thoob thaum kuv lub neej tag nrho hloov dheev thaum hmo ntuj kom zoo dua. Kuv tsis tuaj yeem xav tias nws yog qhov ua tau tias koj tuaj yeem khwv tau nyiaj ntau ntau uas qee qhov trinket thaum xub thawj siab yuav muaj qhov zoo li ntawd. Txhua yam nws tau pib nrog qhov tseeb uas kuv tau txiav txim rau tus kheej.

Lub ntsiab pharmacological lub zog:

• Qeeb qeeb adsorption thiab kev txiav txim siab tsis kawg hauv 24 teev.
• Kev txhawb nqa ntawm proteolysis thiab lipolysis hauv adipocytes.
• Cov nquag tivthaiv khi rau cov tshuaj insulin 5-8 zaug ntau dua.
• Cov kev cai ntawm cov piam thaj hauv cov ntshav, kev txwv tsis pub muaj cov kua nplaum tsim tawm hauv lub siab.

Hauv 1 ml Lantus Solostar muaj:

• 3.6378 mg ntawm insulin glargine (hauv 100 IU ntawm tib neeg cov tshuaj insulin),
• 85% glycerol
• dej rau kev txhaj tshuaj
• hydrochloric concentrated acid,
• m-cresol thiab sodium hydroxide.

Lantus - kua pob tshab rau sc txhaj tshuaj, muaj nyob hauv daim ntawv ntawm:

• cartridges rau OptiKlik system (5pcs ib pob),
• 5 xaum npiv Lantus Solostar,
• OptiSet syringe cwj mem rau hauv ib pob 5 pcs. (kauj ruam 2 units),
• 10 ml vials (1000 units hauv ib lub vial).

Kev ntsuas rau siv

1. Cov neeg laus thiab menyuam yaus txij li 2 xyoos muaj mob ntshav qab zib hom 1.
2. Hom 2 mob ntshav qab zib mellitus (nyob rau hauv cov ntaub ntawv tsis muaj txiaj ntsig ntawm cov ntsiav tshuaj).

Hauv kev rog, kev sib koom ua ke yuav kho tau zoo - Lantus Solostar thiab Metformin.

Kev cuam tshuam nrog lwm yam tshuaj

Muaj cov tshuaj uas cuam tshuam rau cov metabolism hauv cov metabolism, thaum nce los yog txo qis yuav tsum muaj cov insulin.

Txo cov piam thaj: cov tshuaj tiv thaiv kab mob hauv lub cev, sulfonamides, ACE inhibitors, salicylates, angioprotectors, monoamine oxidase inhibitors, antiarrhythmic dysopyramides, narcotic analgesics.

Qab zib kom ntau: cov thyroid hormones, diuretics, sympathomimetics, tshuaj tiv thaiv hauv lub qhov ncauj, phenothiazine derivatives, protease inhibitors.

Qee yam tshuaj muaj ob qho ua kom tsis pom kev thiab qhov ua tsis zoo. Cov no suav nrog:

• beta blockers thiab ntsev lithium,
• cawv
• clonidine (antihypertensive tshuaj).

Cov Yuav Tsum Tau Ua

1. Nws yog txwv tsis pub siv rau hauv cov neeg mob uas tsis nkag siab rau insulin glargine lossis ntu sib xyaw.
2. Kev ntshav siab.
3. Kev kho mob ntawm cov ntshav qab zib ketoacidosis.
4. Cov me nyuam qis dua 2 xyoos.

Ua tau qhov tsis zoo tshwm sim tsawg tsawg, cov lus qhia tau hais tias tej zaum yuav muaj:

• lipoatrophy los yog lipohypertrophy,
• kev ua xua (Quincke's edema, kev tsis haum, tshuaj bronchospasm),
• mob nqaij thiab mob qeeb hauv lub cev ntawm sodium ions,
• mob plab thiab qhov muag tsis pom kev.

Kev Hloov mus rau Lantus los ntawm lwm yam insulin

Yog hais tias tus mob ntshav qab zib tau siv cov tshuaj insulins nyob rau ncua sijhawm, tom qab ntawd thaum hloov mus rau Lantus, kev noj ntau dua thiab kev noj tshuaj hloov pauv. Kev hloov pauv cov kua dej yuav tsum tau nqa tawm hauv tsev kho mob nkaus xwb.

Hauv lub neej yav tom ntej, tus kws kho mob saib cov piam thaj, tus neeg mob lub neej, qhov hnyav thiab kho rau ntau pawg uas tau tswj hwm. Tom qab peb lub hlis, cov hauj lwm zoo ntawm cov tshuaj kho tau tuaj yeem tshawb xyuas los ntawm kev soj ntsuam ntawm glycated hemoglobin.

Kev qhia video:

Zaj dab neeg ntawm ib qho ntawm peb cov neeg nyeem, Inga Eremina:

Kuv qhov hnyav tau tshwj xeeb tshaj yog kev nyuab siab, Kuv hnyav ib yam li 3 tus lej wrestlers ua ke, uas yog 92kg.

Yuav ua li cas tshem tawm qhov hnyav tshaj kom tiav? Yuav daws cov tshuaj hormonal hloov thiab rog dhau li cas? Tab sis tsis muaj dab tsi yog li disfiguring lossis hluas rau ib tus neeg li nws daim duab.

Tab sis yuav ua li cas thiaj poob ceeb thawj? Laser liposuction phais? Kuv pom - tsawg kawg 5 txhiab daus las. Cov txheej txheem kho vajtse - LPG zaws, cavitation, RF nqa, myostimulation? Ib nyuag pheej yig dua - cov nqi kawm ntawm 80 txhiab rubles nrog kws tshaj lij kws paub txog khoom noj khoom haus. Koj muaj peev xwm tiv thaiv sim khiav ntawm lub cos, mus rau qhov tsis pom kev.

Thiab thaum twg kom nrhiav tau txhua lub sijhawm no? Yog thiab tseem kim heev. Tshwj xeeb tam sim no. Yog li ntawd, rau kuv tus kheej, Kuv xaiv txoj kev sib txawv.

Hauv tebchaws Lavxias, txhua tus mob ntshav qab zib insulin-tau raug tshem tawm ntawm Lantus mus rau Tujeo. Raws li kev tshawb nrhiav, cov tshuaj tshiab muaj qhov txo qis ntawm kev noj qab haus huv hypoglycemia, tab sis hauv kev xyaum feem ntau cov neeg yws tias tom qab hloov mus rau Tujeo lawv cov piam thaj tau dhia ntau, yog li lawv raug yuam yuav Lantus Solostar insulin ntawm lawv tus kheej.

Levemir yog cov tshuaj zoo heev, tab sis nws muaj cov tshuaj sib txawv, txawm tias lub sijhawm ua haujlwm kuj yog 24 teev.

Aylar tsis ntsib insulin, cov lus qhia hais tias qhov no yog tib qho Lantus, tab sis cov chaw tsim khoom pheej pheej yig dua.

Insulin Lantus thaum cev xeeb tub

Cov kev tshawb fawb soj ntsuam ntawm Lantus nrog cov poj niam cev xeeb tub tsis tau ua. Raws li cov ntaub ntawv tsis raug cai, cov tshuaj tsis cuam tshuam loj heev hauv chav kawm ntawm cev xeeb tub thiab tus menyuam nws tus kheej.

Cov kev sim tau nrhiav rau ntawm cov tsiaj, thaum lub sijhawm nws tau ua pov thawj tias insulin glargine tsis muaj qhov phiv rau ntawm kev ua me nyuam.

Cev xeeb tub Lantus Solostar tuaj yeem siv tshuaj yog tias tsis muaj zog tiv thaiv NPH. Cov niam yav tom ntej yuav tsum saib xyuas lawv cov suab thaj, vim tias nyob rau thawj peb lub hlis, xav tau cov tshuaj insulin tuaj yeem txo qis, thiab hauv lub hlis thib ob thiab peb lub hlis.

Tsis txhob ntshai tsam pub niam mis rau tus menyuam noj, cov lus qhia tsis muaj cov ntaub ntawv uas Lantus tuaj yeem nkag mus rau niam mis tau.

Lub txee lub neej ntawm Lantus yog 3 xyoos. Koj yuav tsum muab cia rau hauv qhov chaw tsaus tiv thaiv los ntawm tshav ntuj ntawm qhov kub ntawm 2 txog 8 degrees. Feem ntau qhov chaw zoo tshaj plaws yog tub yees. Hauv qhov no, nco ntsoov saib cov txheej txheem kub, vim tias qhov txias khov ntawm cov tshuaj insulin Lantus yog txwv!

Txij li thaum siv thawj zaug, cov tshuaj yuav khaws cia rau ib hlis nyob rau hauv qhov chaw tsaus ntawm qhov kub ntawm tsis ntau tshaj 25 degrees (tsis nyob hauv tub yees). Tsis txhob siv cov tshuaj insulin uas tas sijhawm.

Qhov yuav yuav, nqe

Lantus Solostar yog tshuaj dawb los ntawm kev kho mob los ntawm kev kho mob endocrinologist. Tab sis nws tseem tshwm sim uas tus mob ntshav qab zib yuav tsum yuav cov tshuaj no ntawm nws tus kheej ntawm lub tsev muag tshuaj. Tus nqi nruab nrab ntawm cov tshuaj insulin yog 3300 rubles. Hauv Ukraine, Lantus tuaj yeem yuav rau 1200 UAH.

Tus kws kho ntshav qab zib hais tias nws yog ib qho zoo heev insulin, hais tias lawv qab zib yog khaws cia nyob rau hauv ib txwm txwv. Ntawm no yog cov neeg yuav hais dab tsi txog Lantus:

Feem ntau sab laug tsuas yog cov tshuaj xyuas qhov zoo. Ob peb cov neeg hais tias Levemir lossis Tresiba zoo dua rau lawv.

Tshuav Daim Duab Solostar

Lantus solostar 100ed / ml 3ml 5 pcs. daws rau subcutaneous tswj hwm ntawm lub cartridge. hauv sp.-kov.

Sanofi (Russia) Kev Npaj: Lantus solostar

Cov tshuaj los ntawm pawg Insulin

Actrapid nm 100 u / ml 10 ml txhaj

Novo Nordisk A / C (Denmark) Kev Npaj: Actrapid nm

Qib Qeb 100me / ml 3ml 5 pcs. kev daws rau cov leeg thiab subcutaneous ntawm tus cartridge

Eli Lilly East S.A. (Fabkis) Npaj: Humalog

Biosulin n 100me / ml 3ml 5 pcs. raug muab tshem tawm rau kev coj mus rau subcutaneous ntawm cartridges. hauv sp.-kov.

Pharmstandard Rx (Russia) Kev Npaj: Biosulin n

Levemir flekspen 100ed / ml 3ml 5 pcs. rr-p rau subcutaneous kev tswj hwm ntawm daim cartridges. hauv sp.-kov.

Novo Nordisk A / S (Tebchaws Denmark) Kev Npaj: Levemir flekspen

Kev ntsuas los ntawm qeb ntshav qab zib

5 mg maninil 120 pcs. ntsiav tshuaj

Berlin Chemie (Lub Tebchaws Yelemees) Kev Npaj: Maninil

Gliformin 1000mg 60 pcs. zaj duab xis-ntsiav tshuaj ntsiav tshuaj

Akrikhin (Russia) Kev Npaj: Gliformin

Glurenorm 30mg 60 pcs. ntsiav tshuaj

Beringer Ingelheim Pharma (Lub Tebchaws Yelemees) Kev Npaj: Glurenorm

Siofor 500mg 60 pcs. txheej ntsiav tshuaj

Berlin Chemie (Lub Tebchaws Yelemees) Kev Npaj: Siofor 500

Siofor 850mg 60 pcs. txheej ntsiav tshuaj

Berlin Chemie (Lub Tebchaws Yelemees) Kev Npaj: Siofor 850

LANTUS SoloStar

Cov chaw soj ntsuam thiab chaw muag tshuaj

Yam khoom muaj sia

Tso tawm daim ntawv, muaj pes tsawg leeg thiab ntim khoom

Kev daws rau sc tswj hwm yog pob tshab, xim tsis muaj xim lossis yuav luag tsis muaj xim.

Cov zam: metacresol (m-cresol) - 2.7 mg, zinc chloride - 0.0626 mg (sib xyaw rau 30 μg zinc), glycerol (85%) - 20 mg, sodium hydroxide - txog pH 4.0, hydrochloric acid - txog pH 4.0, dej d / thiab - txog li 1 ml.

3 ml - daim cartridges los ntawm pob tshab, tsis muaj kob (iav I), teeb tsa hauv SoloStar cov ntawv txhaj tshuaj (5) - pob ntawm cov duab los qhia nrog daim npav.

Pharmacological kev txiav txim

Cov tshuaj insulin glargine yog ib qho piv txwv ntawm tib neeg cov tshuaj insulin tau los ntawm kev rov tso cov kab mob DNA ntawm hom Escherichia coli (hom K12) thiab tus cwj pwm los ntawm qis qis solubility hauv ib puag ncig tsis zoo.

Raws li ib feem ntawm cov tshuaj Lantus SoloStar, insulin glargine yog soluble kiag li, uas yog ua los ntawm cov tshuaj tiv thaiv acid ntawm kev daws rau kev txhaj tshuaj (pH 4). Tom qab kev qhia txog cov roj ntsha subcutaneous, cov tshuaj tiv thaiv acidic ntawm cov tshuaj yog neutralized, uas ua rau tsim cov microprecipitate, los ntawm cov tshuaj insulin glargine tso tawm tas li, muab qhov du (tsis muaj peaks) profile ntawm qhov siab-lub sijhawm nkhaus, nrog rau lub sijhawm ntev ntawm cov tshuaj.

Cov tshuaj insulin glargine yog metabolized rau ob lub cev nquag, M1 thiab M2.

Kev sib txuas lus nrog insulin receptors: kev sib txuas lus ntawm kev sib khi rau cov kab mob insulin tshwj xeeb hauv insulin glargine thiab nws cov metabolites M1 thiab M2 yog qhov zoo sib xws rau tib neeg hauv insulin, thiab yog li ntawd insulin glargine muaj peev xwm nqa cov roj ntsha zoo ib yam li cov insulin endogenous.

Qhov kev txiav txim tseem ceeb tshaj plaws ntawm insulin thiab nws cov yeeb yaj kiab, suav nrog thiab insulin glargine, yog kev cai ntawm cov metabolism hauv cov piam thaj. Cov tshuaj Insulin thiab nws cov tshuaj noj kuj txo cov ntsiab lus ntawm cov piam thaj hauv cov ntshav, txhawb kev nqus ntawm cov piam thaj los ntawm cov ntaub so ntswg (tshwj xeeb tshaj yog cov nqaij pob txha thiab cov nqaij adipose) thiab txwv tsis pub muaj cov kua nplaum hauv lub siab. Cov tshuaj insulin inhibits lipolysis hauv adipocytes thiab inhibits proteolysis, thaum nce cov synthesis protein.

Lub sijhawm ntev ua ntawm insulin glargine yog ncaj qha ntsig txog qhov txo tus nqi ntawm nws qhov nqus, uas tso cai rau cov tshuaj no siv 1 sijhawm / hnub. Tom qab kev tswj hwm sc, qhov pib ntawm nws cov kev ua tshwm sim, nyob rau nruab nrab, tom qab 1 teev. Lub sijhawm nruab nrab ntawm kev ua yog 24 teev, qhov siab tshaj plaws yog 29 teev. Lub sijhawm ntawm kev ua ntawm insulin thiab nws cov analogues, xws li insulin glargine, tuaj yeem sib txawv hauv cov neeg mob sib txawv lossis hauv ib tib tug neeg mob.

Qhov ua tau zoo ntawm cov tshuaj Lantus SoloStar hauv cov menyuam yaus hnub nyoog tshaj li 2 xyoos nrog tus mob ntshav qab zib hom 1 tau pom. Hauv cov menyuam yaus hnub nyoog ntawm 2-6 xyoo, qhov tshwm sim ntawm kev mob ntshav qab zib nrog kev soj ntsuam thaum siv insulin glargine tau tsawg dua rau ob leeg nruab hnub thiab hmo ntuj piv rau kev siv tshuaj insulin-isofan (feem ntau, ntawm qhov nruab nrab 25,5 ntu piv rau 33 ntu ntu hauv ib tug neeg mob rau ib xyoos).

Lub sijhawm tsib xyoo rov qab ua tiav ntawm cov neeg mob uas muaj hom 2 mob ntshav qab zib mellitus, tsis muaj qhov sib txawv hauv kev nce qib ntawm tus mob ntshav qab zib retinopathy nrog insulin glargine piv nrog insulin-isophan.

Kev sib raug zoo nrog cov receptors ntawm insulin-zoo li kev loj hlob 1 (IGF-1): kev sib raug zoo ntawm insulin glargine rau IGF-1 receptor yog kwv yees li 5-8 npaug siab tshaj li ntawm tib neeg ntawm insulin (tab sis kwv yees li 70-80 lub sijhawm qis dua IGF-1), tib lub sijhawm, hauv kev sib piv nrog tib neeg cov tshuaj insulin, cov metabolism hauv cov tshuaj insulin glargine M1 thiab M2 kev sib raug zoo rau IGF-1 receptor muaj tsawg dua.

Tag nrho cov tshuaj tua kab mob ntawm cov tshuaj insulin (insulin glargine thiab nws cov metabolites), txiav txim siab hauv cov neeg mob ntshav qab zib hom ntshav qab zib mellitus, tau qis dua qhov kev xav tau tsawg tshaj li ib nrab-qhov siab tshaj plaws rau IGF-1 receptors thiab tom qab ua kom muaj cov kab mob rau txoj kev loj hlob los ntawm IGF-1 receptors. Kev ua kom lub zog ntawm endogenous IGF-1 tuaj yeem ua kom cov teebmeem ntawm txoj kev loj hlob ntawm txoj kev loj hlob, txawm li cas los xij, cov tshuaj tua kab mob insulin ntau qhov kev txiav txim siab thaum lub sij hawm kho mob insulin, suav nrog kev kho mob nrog Lantus SoloStar, yog qhov qis dua qhov kev siv tshuaj uas yuav tsum tau ua kom muaj kev tiv thaiv txoj kev loj hlob.

Kev tshawb nrhiav ORIGIN (Qhov tshwm sim txo qis nrog Kev Pib Pab Rau Lub Pob Glargine INtervention) yog thoob ntiaj teb, ntau tus neeg ua haujlwm, kev tshawb nrhiav kev tshawb fawb hauv 12,537 cov neeg mob uas muaj kev pheej hmoo loj ntawm kev mob plawv thiab tsis hnov ​​qab cov ntshav qabzib (NGN), tsis hnov ​​qab ntawm cov ntshav qabzib (NTG) lossis thaum ntxov ntshav qab zib hom 2. Cov neeg tuaj koom kev tshawb nrhiav tau tsim kho rau hauv pawg (1: 1): ib pawg ntawm cov neeg mob tau txais insulin glargine (n = 6264), uas tau sau npe ua ntej mus txog qhov tsis muaj ntshav qabzib hauv siab (GKN) ≤5.3 mmol, thiab ib pawg ntawm cov neeg mob tau txais kev kho mob (n = 6273 )

Thawj qhov kawg ntawm txoj kev tshawb no yog lub sijhawm ua ntej txoj kev txhim kho kev mob plawv tuag, thawj txoj kev loj hlob ntawm cov mob ntshav tsis txaus myocardial infarction lossis tsis mob ntshav siab, thiab qhov kawg ntawm qhov kawg yog lub sijhawm ua ntej cov kev tsis txaus ntseeg ntawm ib qho twg ntawm cov saum toj no lossis ua ntej cov txheej txheem ntawm revascularization (mob hlab ntsha, carotid lossis peripheral hlab ntsha) , lossis ua ntej pw tsev kho mob rau kev txhim kho lub plawv tsis ua haujlwm.

Cov kab mob tsis kawg yog txoj kev tuag nyob rau ib qho laj thawj thiab kev ntsuas ua ke ntawm cov txiaj ntsig microvascular.

Kev tshawb fawb ORIGIN tau qhia tias kev kho mob insulin glargine piv rau kev kho tus mob hypoglycemic tsis hloov txoj kev pheej hmoo ntawm cov mob plawv los yog mob plawv tuag, tsis muaj qhov sib txawv ntawm cov nqi ntawm ib feem twg los ua cov ntsiab lus xaus, kev tuag ntawm txhua qhov ua ke, kev ntsuas ua ke ntawm cov txiaj ntsig microvascular. Cov.

Thaum pib ntawm kev kawm, qhov nruab nrab Hb A1c qhov tseem ceeb yog 6.4%. Qhov nruab nrab Hb A1c qhov tseem ceeb thaum kho yog nyob rau ntawm 5.9-6.4% hauv pawg insulin glargine thiab 6.2-6.6% hauv pawg kho mob thoob plaws lub sijhawm tshuaj xyuas.

Hauv pawg ntawm cov neeg mob tau txais insulin glargine, qhov tshwm sim ntawm kev mob ntshav qab zib ntau yog 1.05 ntu kev mob ib zaug rau 100 tus neeg mob lub xyoo ntawm kev kho, thiab hauv cov pab pawg ntawm cov neeg mob uas tau txais kev kho tus mob hypoglycemic 0.3 ntu kev tshwm sim rau 100 tus neeg mob-xyoo ntawm kev kho. Qhov tshwm sim ntawm kev mob ntshav qab zib tsawg yog 7,71 ntu kev tshwm sim rau 100 tus neeg mob lub xyoo ntawm kev kho mob hauv pawg ntawm cov neeg mob tau txais insulin glargine, thiab 2.44 ntu kev tshwm sim rau 100 tus neeg mob-xyoo ntawm kev kho nyob rau hauv pab pawg ntawm cov neeg mob tau txais kev mob ntshav qab zib tsawg. Hauv kev tshawb fawb 6-xyoo, 42% ntawm cov neeg mob hauv cov pab pawg insulin glargine tsis tau pom tias muaj cov ntshav qog ntshav qab zib tsawg.

Qhov nruab nrab ntawm qhov hloov ntawm lub cev qhov hnyav piv nrog cov txiaj ntsig ntawm kev mus ntsib zaum kawg yog 2.2 kg siab dua ntawm cov tshuaj insulin glargine pab pawg dua li pawg kho mob.

Dosage daim ntawv

Kev daws rau kev txhaj tshuaj 100 IU / ml

1 ml ntawm cov tshuaj muaj:

cov tshuaj nquag: insulin glargine NOE 901 - 3.6378 mg (100 PIECES).

kev zam: metacresol, zinc chloride, glycerin (85%), sodium hydroxide, concentrated hydrochloric acid, dej rau kev txhaj tshuaj.

Transparent tsis muaj kob lossis yuav luag tsis muaj cov kua.

Cov chaw muag tshuaj

Piv rau tib neeg NPH-insulin, ntshav dej insulin ntau hauv cov ntsiab lus noj qab haus huv thiab cov neeg mob ntshav qab zib tom qab kev saib xyuas ntawm insulin glargine qhia tau qeeb dua thiab ua rau lub siab ntev dua, nrog rau qhov tsis muaj lub siab tshaj. Yog li, qhov ntau ntau tau ua raws li cov qauv ntawm ntu ntawm cov chaw muag khoom ua haujlwm ntawm insulin glargine. Daim duab 1 qhia txog cov haujlwm kev ua ntawm insulin glargine thiab NPH-insulin tiv thaiv lub sijhawm. Nrog cov lus qhia ntawm ib zaug ib hnub, qhov sib luag ntawm cov tshuaj insulin glargine nyob rau hauv cov ntshav tau tiav 2-4 hnub tom qab txhaj thawj zaug. Nrog kev tswj hwm intravenous, ib nrab-lub neej ntawm insulin glargine thiab insulin tib neeg tau sib piv.

Tom qab subcutaneous txhaj ntawm Lantus hauv cov neeg mob ntshav qab zib mellitus, insulin glargine yog sai metabolized thaum kawg ntawm polypeptide beta saw los ua ob lub cev siv tshuaj tiv thaiv M1 (21A-Gly-insulin) thiab M2 (21A-Gly-des-30B-Thr insulin). Hauv ntshav, cov kab mob loj ntawm lub voj voog yog cov tshuaj metabolite M1. Qhov kev tshwj xeeb ntawm cov metabolite M1 nce ntxiv raws li qhov tau hais tseg ntawm Lantus.

Pharmacokinetic thiab pharmacodynamic cov txiaj ntsig tau qhia tias cov nyhuv ntawm subcutaneous txhaj ntawm Lantus feem ntau yog ua raws li kev rho tawm ntawm metabolite M1. Insulin glargine thiab metabolite M2 tsis pom nyob rau hauv cov neeg mob feem ntau, thaum lawv nrhiav tau, lawv qhov kev tsom xam yog ywj siab ntawm cov tshuaj Lantus.

Hauv kev sim kho mob, kev soj ntsuam ntawm pawg neeg tau tsim los ntawm lub hnub nyoog thiab poj niam txiv neej tsis qhia txog qhov txawv ntawm qhov ua tau zoo thiab kev nyab xeeb ntawm cov neeg mob kho nrog insulin glargine thiab tag nrho cov pej xeem tau kawm.

Pharmacokinetics rau cov menyuam yaus hnub nyoog 2 txog 6 xyoo uas muaj ntshav qab zib hom 1 tau raug soj ntsuam hauv ib qhov kev tshawb fawb soj ntsuam (saib "Pharmacodynamics"). Qhov "ntshav" qis kawg ntawm cov ntshav ntawm insulin glargine thiab nws lub ntsiab metabolites M1 thiab M2 tau ntsuas rau cov menyuam yaus raug kho nrog insulin glargine, thiab nws tau pom tias plasma ntau ntau zoo ib yam li cov qauv hauv cov neeg laus, cov pov thawj txhawb kev tsub zuj zuj ntawm insulin glargine lossis nws cov metabolites. nrog rau kev tswj hwm ncua ntev yog tsis tuaj.

Insulin glargine yog ib qho piv txwv ntawm tib neeg cov kua dej, tsim kom muaj cov solubility qis ntawm pH nruab nrab. Nws yog kiag li soluble ntawm acidic pH ntawm Lantus® Txhaj Tshuaj (pH 4). Tom qab kev tswj hwm subcutaneous, cov tshuaj acidic yog nruab nrab, ua rau muaj kev tsim cov microprecipitate, los ntawm cov tshuaj insulin glargine txuas ntxiv tso tawm me me, muab ib qho tseem ceeb, tsis pub dawb, kom paub tseeb txog lub sijhawm / lub sijhawm nrog kev ua haujlwm ntev.

Kev khi rau cov tshuaj insulin: hauv kev tshawb fawb hauv vitro qhia tau tias qhov sib thooj ntawm insulin glargine thiab nws cov metabolites M1 thiab M2 rau tib neeg cov tshuaj insulin yog tib yam rau tib neeg cov insulin.

IGF-1 receptor khi: qhov sib thooj ntawm insulin glargine rau tib neeg IGF-1 receptor yog kwv yees li 5-8 npaug ntau dua li ntawm tib neeg ntawm insulin (tab sis kwv yees li 70-80 npaug qis dua IGF-1), thaum M1 metabolites. thiab M2 khi rau IGF-1 receptor nrog kev sib txuam me ntsis piv rau tib neeg cov insulin.

Tag nrho cov tshuaj tua kab mob ntawm cov tshuaj insulin (insulin glargine thiab nws cov metabolites), txiav txim siab hauv cov neeg mob ntshav qab zib hom ntshav qab zib, tsawg tshaj li qhov yuav tsum tau ua rau ib nrab cov lus teb tshaj plaws los ntawm kev ntes ntawm IGF-1 receptor thiab tom qab ua kom muaj cov kab mob rau txoj kev ua kom cov kab mob ua rau muaj IGF-1 receptor. Cov. Kev tawm dag zog lub zog ntawm endogenous IGF-1 tuaj yeem ua kom cov kab mob ntawm txoj kev loj hlob ntawm txoj kev loj hlob, txawm li cas los xij, kev kho mob ntau yam tau txiav txim siab thaum lub sij hawm kho mob insulin, suav nrog kev kho Lantus, nws qis dua qhov kev siv tshuaj pharmacological xav tau kom ua IGF-1 txoj kev.

Kev ua haujlwm thawj zaug ntawm insulin, suav nrog insulin glargine, yog tswj kev metabolism hauv qabzib. Cov tshuaj insulin thiab nws cov kab mob sib txig txo cov ntshav qabzib ntau ntau ntxiv los ntawm kev nce ntxiv cov piam thaj hauv cov ntaub so ntswg, tshwj xeeb tshaj yog cov leeg pob txha thiab adipose cov nqaij, zoo li los ntawm kev tsim cov piam thaj hauv siab. Cov tshuaj Insulin muab cov lipolysis hauv adipocytes, inhibits proteolysis thiab txhim kho cov protein synthesis. Cov kev tshawb fawb soj ntsuam thiab pharmacological tau qhia tias kev muab cov tshuaj insulin glargine thiab tib neeg cov tshuaj insulin yog qhov sib npaug thaum muab rau tib zaug. Ib yam li txhua yam insulins, kev tawm dag zog thiab lwm yam tuaj yeem cuam tshuam lub sijhawm ntawm kev ua ntawm insulin glargine.

Daim ntawv tso tawm

Cov tshuaj insulin muaj nyob rau hauv cov phwj ntoo. Qhov no yog daim foos yooj yim rau cov neeg mob ntshav qab zib, txij li kev txhaj tshuaj tuaj yeem nqa tsis tau hauv tsev nkaus xwb, tab sis kuj siv sab nraum lub tsev. Nrog kev pab los ntawm ib tug cwj mem, nws yog qhov yooj yim kom muaj peev xwm tiv thaiv qhov ntau npaum li cas, yog li overdose mob tsis tshua muaj neeg mob. Cov pob muaj 5 cartridges ntawm 3 ml. Cov tshuaj tau ntim rau hauv lub thawv ntawv, nws kuj muaj cov lus qhia rau kev siv nrog cov ncauj lus qhia ntxaws ntawm kev siv cov khoom no. Lub chaw tsim tshuaj yog Frankfurt am Main Tebchaws Yelemees, kev tsim cov tshuaj ntawm Lavxias yog ZAO Sanofi-Aventis Vostok, Oryol Oblast.

Pharmacodynamics thiab pharmacokinetics

Cov tshuaj yog tsim nyob rau hauv xws li txoj kev uas nws muaj solubility tsawg nyob rau hauv nruab nrab acidic ib puag ncig. Hauv kev txhaj tshuaj dej nws yaj tau zoo thiab kom huv. Tom qab txhaj tshuaj subcutaneous, qhov nruab nrab acidic ua rau nruab nrab, thiab cov tshuaj khom tawm hauv daim ntawv ntawm microcrystals, uas maj mam nkag mus rau cov ntshav. Qhov no piav qhia txog nws qhov kev txiav txim siab ntev. Insulin garling txhim kho cov piam thaj tuaj yeem los ntawm cov ntaub so ntswg, tshwj xeeb tshaj yog cov nqaij pob txha thiab cov nqaij rog, thiab txo cov piam thaj hauv siab. Yog li, txo qis hauv cov ntshav qab zib tshwm sim. Yog tias peb piv cov kev ua ntawm isophane thiab harling, thib ob ua ntau dua maj mam, yam tsis muaj qhov siab. Kev nqus qis ntawm cov tshuaj ua rau nws tuaj yeem siv nws ib hnub ib zaug.

Raws li qib kev khi rau insulin receptors, harling thiab tib neeg cov insulin yog qhov zoo heev, yog li ntawd, txhaj tshuaj ntawm cov tshuaj tau zoo rau cov neeg mob thiab muab qhov tshwm sim xav tau. Qhov kev ruaj khov ruaj khov ntawm cov tshuaj yog pom tom qab 2-4 hnub los ntawm thawj qhov txhaj tshuaj nrog kev tswj hwm niaj hnub. Cov neeg mob pom tau tias pib kho mob nyhuv 60 feeb tom qab txhaj tshuaj, qhov siv tshuaj siv tau ntev li 24-29 teev. Thaum nkag mus rau hauv lub cev, Lantus, zoo li txhua yam insulins, muaj kev puas tsuaj thiab yog tawm hauv cov zis thiab cov kua tsib.

Tseem Ceeb! Siv tus xwj xem hluav taws xob raws li qhov teev tseg. Nws yog ib qho tsim nyog yuav tsum txhaj tshuaj insulin subcutaneously mus rau hauv plab plab, sab ceg (ncej puab), xub pwg.

Kev taw qhia thiab contraindications

Cov tshuaj insulin koom nrog hauv cov txheej txheem ntawm cov piam thaj ua rau tawg, thiab nws lub cev tsis txaus ua rau kev tsub zuj zus ntawm cov piam thaj hauv cov ntshav, ua rau koj tsis zoo siab. Solostar yog siv los kho cov tshuaj insulin-tiv thaiv kev mob uas muaj cov tshuaj lom lawm. Xws li tus kab mob kev tsim tawm vim qhov tsis txaus cov leeg phais vim muaj kabmob los yog tsim ua. Solotar muaj qhov sib xyaw nrog lwm cov tshuaj insulin. Hauv qhov no, nws yog qhov yuav tsum tau los laij cov tshuaj sib txawv, xaiv nws coj mus rau hauv tus lej qhov sib txawv hauv lub sijhawm ua. Kev sib xyaw ua ke yog siv los kho hom 2 ntshav qab zib.

Qhov kom ua tiav ntawm kev siv Harling yog:

• kev tsis haum tshuaj rau cov tshuaj thiab cov tshuaj nquag,
• mob raum tsis ua haujlwm,
• tus me nyuam qis dua 2 xyoos.

Tus txheeb ze tsis sib haum yog xeeb tub. Cov pojniam xeebtub yuav tsum tau txhaj tshuaj insulin nyob rau hauv kev tswj cov ntshav qab zib kom nyob mus ib txhis. Thoob plaws hauv lub cev xeeb tub, yuav tsum tau txhaj tshuaj 2-3 zaug kev kho mob, yog li, kev kho tshuaj insulin yuav tsum tau saib xyuas los ntawm kws kho mob.

Sab sij huam

Ua raws li cov tshuaj pom zoo, tsis txaus ntseeg lub cev tsis tshua muaj tshwm sim. Tab sis kev siv insulin ntev ntev tuaj yeem ua rau "phiv".Feem ntau cov feem ntau, qhov no yog qhov txo qis hauv qab zib qib, uas ua rau nws tus kheej:

• tsis muaj zog
• qhov muag plooj
• ua txhaum ntawm lub hauv nruab nrab lub paj hlwb,
• tsaus muag
• tshee ntawm nqua,
• hypehydrosis,
• lub plawv dhia muaj zog.

Nrog ib qho kev tso tawm zuj zus hauv qabzib hauv qab theem, qhov ua kom lub ntsej muag tsis tsaug zog tuaj yeem txhim kho, uas yog qhov mob tseem ceeb uas yuav tsum tau kho mob sai. Ntxiv rau, tus kab mob ntshav qab zib yuav muaj qhov chaw ua si ntawm thaj chaw uas nquag mus txhaj, yog li thaj chaw txhaj tshuaj yuav tsum tau hloov. Yog tias tsis ua raws li kev nyiam huv, qhov chaw txhaj tshuaj yuav kis tau tus mob, ua rau kom ua paug, khaus thiab yaug. Cov neeg mob uas ua xua lossis muaj keeb kwm ntawm kev poob siab mob hlwb los soj ntsuam cov tshuaj ua kom tsis taus insulin. Rau qhov no, kev txhaj tshuaj intradermal yog tsim thiab cov tshuaj tiv thaiv ntawm lub cev raug saib xyuas. Yog tias tsis muaj qhov tshwm sim tsis zoo, txuas ntxiv cov tshuaj insulin.

Tsuas tshuaj thiab tshaj

Lantus yog qhia txog kev kho mob ntshav qab zib rau cov laus, cov hluas thiab cov menyuam yaus txij li 2 xyoos. Yog tias tshuaj insulin xav tau rau tus menyuam hnub nyoog qis dua ob xyoos, ces qhov koob tshuaj tau txiav txim siab ncaj qha rau nws tus kheej thiab muab xam rau ntawm lub cev qhov hnyav ntawm tus menyuam. Cov chaw tsim tshuaj ntawm cov tshuaj hauv cov lus qhia kom meej meej qhia yuav ua li cas thiab nyob qhov twg los tswj cov tshuaj. Cov tshuaj insulin raug txhaj rau cov neeg laus thiab menyuam yaus subcutaneously ib hnub ib zaug, tsis hais lub sijhawm nruab hnub, tab sis tib lub sijhawm. Qhov ntau thiab tsawg ntawm cov tshuaj yuav tsum tau xam ib tus zuj zus.

Nrog hom 2 mob ntshav qab zib mellitus, Solostar ua yeeb tshuaj ib leeg, nrog rau kev sib koom tes nrog pab pawg. Koj yuav tsum tau hloov kho qhov ntau ntawm cov tshuaj thaum hloov los ntawm ib hom tshuaj insulin mus rau lwm tus, nrog rau qhov nce hauv lub cev, hloov sij hawm ntawm kev txhaj tshuaj. Cov xwm txheej no ua rau cov nyhuv ntawm tshuaj, yog li ntawd, xav tau cov lej tshiab. Ua ntej siv cov cwj mem-xaum, kws kho mob piav qhia rau tus neeg mob yuav ua li cas txhaj, ntxig ib rab koob, thiab xaiv qhov chaw haum rau kev txhaj tshuaj. Qhov kev siv dag siv tsis tas yuav muaj kev txawj ntse tshwj xeeb, vim tias cov koob txhaj tshuaj tsis muaj lub ntsej muag thiab lub koob txhaj tshuaj tsis muaj dag zog. Muaj ib qho tsis txaus ntseeg nyob rau hauv tus txheej txheem - tus mob ntshav qab zib yuav tsum kawm kom paub kev ntsuas tus kheej ntawm qhov ntsuas qhov ntsuas qhov tsim nyog rau kev tswj hwm.

Tseem Ceeb! Txhawm rau tshem tawm kev sib kis ntawm qhov chaw txhaj tshuaj, siv koob ib zaug. Tom qab txhaj tshuaj thawj zaug, tus cwj mem xaum cia rau hauv qhov chaw tsaus ntawm chav sov thiab siv tsis tshaj 1 hlis.

Yog hais tias tus neeg mob laus lossis muaj mob ntawm qhov txo qis hauv qhov muaj peev xwm ntawm lub raum, zoo li thaum hloov los ntawm nruab nrab lossis yooj yim insulin rau Solestar, qhov me me ntawm garglin yog kho. Tsuas yog kws kho mob tuaj yeem suav qhov no. Feem ntau, "Lantus" tau sau tseg hauv 40-60% ntawm cov koob tshuaj uas tau siv yav dhau los. Kev siv tshuaj tsawg yog tawm rau cov neeg mob noj cov tshuaj uas muaj cov nyhuv hypoglycemic.

Overdose ntawm cov tshuaj tshwm sim raws li ib qho tshwm sim ntawm:

• yuam kev tswj hwm ntawm nce koob tshuaj,
• muab xam tsis yog,
• hloov chaw txhaj tshuaj,
• siv lwm hom tshuaj insulin.

Hauv qhov no, tus neeg mob txhim kho hypoglycemia nrog cov duab sib piv hauv chaw kuaj mob. Txoj kev kho mob yog xwm txheej ceev, tshwm sim.

Kev sib txuam

Nrog rau kev tswj hwm ntawm Lantus thiab cov tshuaj los ntawm lwm pawg pharmacological, kev hloov lub sijhawm ntawm insulin ua yog pom. Qee cov tshuaj tuaj yeem txhim kho qhov kev ua haujlwm ntawm insulin, thaum lwm tus tuaj yeem txo cov nyhuv kho. Ib qho kev nce hauv cov nyhuv hypoglycemic yog pom nrog kev sib cuam tshuam ntawm harling nrog:

• ACE inhibitors, MAO,
• salicylic acid npaj
• sulfnilamide tus neeg sawv cev
• cov tshuaj tiv thaiv qhov ncauj hypoglycemic.

Kev txo qis cov tshuaj insulin yog tshwm sim los ntawm:

• cawv
• noj tshuaj uas muaj cov thyroid hormones,
• tshuaj kho mob
• tshuaj kho mob
• tshuaj psychotropic.

Thaum sau ntawv ntawm insulin harling, koj yuav tsum xyuas seb puas muaj lwm yam tshuaj uas tus neeg mob tau noj txhawm rau txhawm rau txhawm rau ntsuas qhov tseeb koob tshuaj.

Hloov maj mam los yog cov lus zoo sib xws rau Lantus Solostar muaj cov nyhuv zoo sib xws, tab sis txawv ntawm cov txheej txheej pabcuam.

Lub rooj muab ib daim ntawv teev cov analogues ntawm cov tshuaj.

Qhov hloov tshiab ntawm Lub Cev Lantus yog Tujeo Solostar Nws tsis tshua muaj qhov ua rau "tshwm sim", thiab kom ua tiav cov txiaj ntsig kho qhov mob uas xav tau, yuav tsum muaj 3 zaug me dua li Lantus. Cov tshuaj tawm rau hauv tus cwj mem syringe. Nyob rau ntawm thawj muaj cov ntawv sau 300ED ntawm cov keeb kwm yav dhau zib-kub. Yees duab:

Qhov twg ntawm cov analogues yuav tsim nyog rau tus neeg mob, tus kws kho mob txiav txim siab, coj mus rau hauv tus kws kho mob hauv chav kho mob thiab tus neeg mob lub mob.

Cov neeg mob, nrog rau cov kws kho mob, tawm lawv cov kev tawm tswv yim hauv Is Taws Nem txog cov tshuaj no.

Angelina, 37 xyoo, endocrinologist. Lantus thiab Tugiero muaj cov khoom xyaw ua ke, tab sis hauv kev npaj lawv muaj kev mloog zoo. Tujeo muaj ntau dua qhov xav tau ntawm tus mob ntshav qab zib, vim tias yuav tsum tau noj tshuaj ntau dua yog xav kom qab zib li qub.

Anna, 32 xyoo. Siv Lantus, ces hloov mus rau Tujeo. Kuv nyiam nws ntau dua, tsis muaj "phiv", qab zib yog qhov qub.

Vladislav, 46 xyoo. Kuv tau muaj mob ntshav qab zib tau 10 xyoo. Ua ntej, nws txhaj tshuaj Basis Insulin, tom qab ntawd Lantus. Tam sim no hloov mus rau Tujeo. Kuv hnov ​​zoo, tsis muaj kev phiv tshuaj, tab sis kuv tsis hnov ​​qab txog kev noj haus.

Tus nqi ntawm "Lantus" hauv cov khw muag tshuaj hauv tebchaws Russia txawv ntawm 2900 txog 3200 rubles rau ib pob.