Metfogamma 1000: cov lus qhia rau kev siv, nqe, qab zib ntsiav tshuaj analogues
Metfogamma 1000 (ntsiav tshuaj) Ntsuam xyuas: 8
Chaw tsim tshuaj paus: Vörwag Pharma GmbH & Co. KG (Lub Teb Chaws Yelemees)
Cov Ntawv Tso Tawm:
- Ntsiav tshuaj 1000 mg, 30 pcs., Nqe los ntawm 176 rubles
Cov lus qhia rau kev siv
Lwm cov tshuaj rau ntshav qab zib hauv cov ntsiav tshuaj tso tawm. Muag hauv cov thawv muag khoom ntawm 30 ntsiav tshuaj uas muaj metformin hydrochloride ua cov khoom xyaw ua zaub mov. Contraindicated thaum cev xeeb tub thiab pub niam mis.
Nqe thiab txoj ntsiab cai ntawm kev txiav txim ntawm cov tshuaj
Tus tshuaj ntau npaum li cas? Tus nqi nyob ntawm tus nqi ntawm metformin hauv cov tshuaj. Rau Metfogamma 1000 tus nqi yog 580-640 rubles. Metfogamma 500 mg nqi txog 380-450 rubles. Ntawm Metfogamma 850 tus nqi pib los ntawm 500 rubles. Nws yog tsim nyog sau cia tias cov tshuaj tau muab faib tawm tsuas yog los ntawm cov tshuaj noj.
Lawv ua tshuaj nyob hauv tebchaws Ntsaws Mes Nis. Cov nom sawv cev hauv chaw lis haujlwm sawv cev hauv nroog Moscow. Xyoo 2000, kev tsim khoom siv tshuaj kho mob tau tsim nyob hauv lub nroog Sofia (Bulgaria).
Lub hauv paus ntsiab lus ntawm kev ua yeeb tshuaj raws li yog dab tsi? Metformin (cov tshuaj tiv thaiv tseem cuam tshuam) txo cov ntsiab lus ntawm cov piam thaj hauv cov ntshav. Qhov no yog ua tiav los ntawm kev tswj hwm gluconeogenesis nyob rau hauv daim siab. Metformin kuj tseem txhim kho kev siv cov piam thaj hauv cov nqaij thiab txo qhov kev nqus ntawm qab zib los ntawm kev mob plab.
Nws yog qhov tsim nyog tias thaum siv cov tshuaj, cov theem ntawm cov cholesterol thiab LDL hauv cov ntshav cov ntshav yog txo qis. Tab sis Metformin tsis hloov pauv qhov lipoproteins. Thaum siv cov tshuaj koj tuaj yeem poob ceeb thawj. Feem ntau, 500, 850, thiab 100 mg metogram yog siv thaum kev noj haus tsis pab txo lub cev qhov hnyav.
Metformin tsis tsuas yog txo qis cov ntshav qab zib, tab sis kuj tseem txhim kho cov khoom fibrinolytic ntawm cov ntshav.
Qhov no ua tiav los ntawm kev ua kom cov nqaij mos-plasminogen inhibitor.
Cov lus qhia rau kev siv tshuaj
Qhov xwm txheej twg yog kev siv cov tshuaj Metfogamma 500 siv tau dawb? Cov lus qhia rau kev siv hais tias cov tshuaj yuav tsum tau siv rau hauv kev kho mob ntawm cov tshuaj tsis muaj tshuaj tua kabmob ntshav qab zib hom 2. Tab sis Metfogamma 1000, 500 thiab 800 mg yuav tsum tau siv rau hauv kev kho mob ntawm cov neeg mob uas tsis nquag ketoacidosis.
Yuav noj cov tshuaj li cas? Cov koob tshuaj yog xaiv raws qib uas cov piam thaj hauv cov ntshav. Feem ntau, cov tshuaj pib yog 500-850 mg. Yog tias cov tshuaj raug siv los tswj cov dej qab zib ib txwm, ces cov tshuaj txhua hnub yuav nce ntxiv rau 850-1700 mg.
Koj yuav tsum tau noj cov tshuaj hauv 2 qhov faib ua ob zaug. Kuv yuav tau noj tshuaj ntev npaum li cas? Txog Metfogamma 850, cov kev qhia tsis tswj cov sijhawm kho. Lub sijhawm rau kev kho mob yog xaiv tau ntawm tus kheej thiab nyob ntawm ntau yam.
Hauv Metfogamma 1000, cov lus qhia rau kev siv tswj cov kab mob sib kis rau kev siv:
- Ntshav qab zib ketoacidosis.
- Ua txhaum ntawm ob lub raum.
- Lub plawv tsis ua hauj lwm.
- Cerebrovascular kev huam yuaj.
- Kev haus cawv mus ntev
- Lub cev qhuav dej.
- Cov theem mob myocardial infarction.
- Daim siab ua hauj lwm.
- Haus dej cawv.
- Cov kab mob lactic acidosis
- Cev xeeb tub
- Lub sijhawm lactation.
- Kev fab tshuaj rau metformin thiab ntu sib txuam ntawm cov tshuaj.
Kev tshuaj xyuas ntawm cov kws kho mob tau taw qhia tias cov tshuaj yuav tsum tsis txhob siv thaum noj zaub mov muaj calorie tsawg, uas yuav tsum noj tsawg dua 1000 calories ib hnub. Txwv tsis pub, cov tshuaj Metfogamma 1000 tuaj yeem ua rau mob hnyav ntxiv, nce txog kev mob ntshav qab zib tsis nco qab lawm.
Cov tshuaj yog feem ntau ua tau zoo los ntawm cov neeg mob. Tab sis nrog kev siv lub caij nyoog ntev ntawm kev siv tshuaj, qhov ntxim nyiam ntawm cov kev mob tshwm sim xws li:
- Megaloblastic anemia.
- Kev ua txhaum nyob rau hauv kev ua haujlwm ntawm txoj hnyuv. Metfogamma 1000 tuaj yeem ua rau kev txhim kho ntawm cov tsos mob dyspeptic, xeev siab, ntuav thiab raws plab. Tsis tas li thaum kho kev kho mob, nws yog xim hlau uas yuav tshwm hauv qhov ncauj.
- Kev ntshav siab.
- Cov kab mob lactic acidosis.
- Kev ua xua tsis haum.
Kev tsim kho ntawm cov kab mob lactic acidosis qhia tau tias nws zoo dua los cuam tshuam txoj kev kho mob.
Yog tias qhov tshwm sim no tshwm sim, kev kho mob cov tsos mob yuav tsum tau txais tam sim ntawd.
Tshuaj thiab Yeeb Tshuaj Sib Pauv
Tshuaj metfogamma 1000 cuam tshuam nrog lwm cov tshuaj li cas? Cov lus qhia tau hais tias kev noj tshuaj muaj peev xwm txo qis kev ua haujlwm ntawm kev kho mob nrog kev siv tshuaj anticoagulants.
Nws tsis pom zoo siv tshuaj kho mob ntshav qab zib nrog rau MAO inhibitors, ACE inhibitors, clofibrate derivatives, cyclophosphamides lossis beta-blockers. Nrog rau kev sib cuam tshuam ntawm metformin nrog rau cov tshuaj saum toj no, qhov kev pheej hmoo ntawm nce hypoglycemic kawg nce.
Dab tsi yog qhov piv tau zoo tshaj plaws ntawm Metfogamma 1000? Raws li kws kho mob, qhov zoo tshaj plaws yog:
- Glucophage (220-400 rubles). Cov tshuaj no zoo ib yam li Metfogamma. Cov tshuaj tiv thaiv nquag siv tshuaj yog metformin. Cov tshuaj pab txo qis cov ntshav qab zib thiab ua rau kom nkag siab zoo ntawm cov tshuaj insulin peripheral.
- Glibomet (320-480 rubles). Cov tshuaj inhibits lipolysis nyob rau hauv cov nqaij mos adipose, txhawb kev kub ntxhov ntawm cov ntaub so ntswg mus rau kev ua ntawm insulin thiab txo cov ntshav qab zib.
- Siofor (380-500 rubles). Cov tshuaj inhibits qhov nqus ntawm cov piam thaj hauv txoj hnyuv, txhim kho kev siv suab thaj hauv cov nqaij ntshiv thiab txo qis tsim cov piam thaj hauv daim siab.
Cov tshuaj saum toj no raug pom zoo rau siv nrog tsis muaj tshuaj insulin-hom ntshav qab zib hom 2. Thaum xaiv cov tshuaj analogue, koj yuav tsum sab laj nrog koj tus kws kho mob, vim tias tshuaj kom txo cov piam thaj tuaj yeem ua rau mob lactic acidosis. Cov yeeb yaj kiab hauv tsab xov xwm no txuas ntxiv lub ntsiab lus ntawm kev siv Metformin rau cov ntshav qab zib.
Cov tshuaj ntawm cov tshuaj Metfogamma 1000
Cov analogue yog pheej yig dua los ntawm 66 rubles.
Chaw tsim tshuaj paus: Merck Sante SAA.S. (Fab Kis)
Cov Ntawv Tso Tawm:
- Ntsiav tshuaj 500 mg, 30 pcs., Nqe los ntawm 110 rubles
- Ntsiav tshuaj 1000 mg, 30 pcs., Nqe los ntawm 185 rubles
Cov lus qhia rau kev siv
Fab kis tshuaj kho tus mob ntshav qab zib hom 2. Muag hauv cov ntsiav tshuaj muaj txog 500 txog 1000 mg ntawm metformin ua cov tshuaj tiv thaiv kab mob ib leeg. Muaj contraindications, yog li ntawd, ua ntej noj Glucofage, nws yog qhov yuav tsum tau sab laj nrog tus kws tshaj lij.
Cov analogue yog pheej yig dua los ntawm 67 rubles.
Chaw tsim tshuaj paus: Akrikhin (Russia)
Cov Ntawv Tso Tawm:
- Ntsiav tshuaj 500 mg, 60 pcs., Nqe los ntawm 109 rubles
- Ntsiav tshuaj 850 mg, 60 pcs., Nqe los ntawm 190 rubles
Cov lus qhia rau kev siv
Gliformin yog tshuaj siv hauv tsev rau kev kho mob ntshav qab zib hom 2. Muag rau hauv cov qauv ntawm cov ntsiav tshuaj nrog metformin ua tus tsuas ua hauj lwm (noj ntau npaum li 250 lossis 500 mg yog ua tau). Gliformin muaj cov npe loj tshaj plaws ntawm contraindications, yog li ua ntej pib kev kho mob, nco ntsoov nyeem cov lus qhia ntawm kev ua haujlwm rau kev siv.
Cov analogue yog pheej yig dua los ntawm 119 rubles.
Chaw tsim tshuaj paus: Cov Tshuaj Zoo Li Qub-Leksredstva (Russia)
Cov Ntawv Tso Tawm:
- Tab. 50 mg, 30 pcs., Nqe txij li 57 rubles
- Tab. 50 mg, 60 pcs., Nqe ntawm 99 rubles
Cov lus qhia rau kev siv
Formmetin yog qhov hloov pheej yig rau Glucofage, tsim los txo cov ntshav qabzib. Muaj nyob rau hauv cov ntsiav tshuaj muaj 0.5, 0.85 lossis 1 g ntawm metformin. Nws tuaj yeem ua rau lub cev ua rau lub plab tsis zoo, ua pob rau ntawm daim tawv nqaij, thiab yog tias muaj kev noj ntau dhau - lub qog ntshav thiab cov kab mob lactic acidosis tuaj yeem ua rau tuag taus.
Ib qho hluav taws xob tsis kim dua los ntawm 2 rubles.
Chaw tsim tshuaj paus: Hemofarm A.D. (Serbia)
Cov Ntawv Tso Tawm:
- Tab. 500 mg, 60 pcs., Nqe txij li 178 rubles
- Tab. 50 mg, 60 pcs., Nqe ntawm 99 rubles
Cov lus qhia rau kev siv
Metformin yog ib qho tshuaj Serbian hypoglycemic rau kev siv sab hauv. Cov tshuaj muaj pes tsawg leeg ntawm cov ntsiav tshuaj muaj cov khoom xyaw nquag ntawm tib lub npe hauv tshuaj ntau npaum 500 lossis 850 mg. Nws yog tshuaj rau kev kho mob ntshav qab zib hom 2 (hauv cov neeg laus), tshwj xeeb yog cov muaj rog.
Cov analogue kim dua los ntawm 209 rubles.
Chaw tsim tshuaj paus: Kimika Montpellier S.A. (Argentina)
Cov Ntawv Tso Tawm:
- Ntsiav tshuaj 1000 mg, 60 pcs., Nqe los ntawm 385 rubles
- Tab. 50 mg, 60 pcs., Nqe ntawm 99 rubles
Cov lus qhia rau kev siv
Argentinean ntsiav tshuaj tshuaj los kho mob ntshav qab zib. Bagometres ua raws li kev siv cov tshuaj metformin hydrochloride ntau npaum li 500 mg rau ib ntsiav tshuaj. Nws yog tshuaj rau ntshav qab zib hom 2.
Analogs hauv kev muaj pes tsawg leeg thiab qhia txog kev siv
| Npe | Nqe hauv Lavxias | Nqe hauv Ukraine |
|---|---|---|
| Bagomet Metformin | -- | 30 UAH |
| Glucofage metformin | 12 RUB | 15 UAH |
| Globophage xr metformin | -- | 50 UAH |
| Reduxin Met Metformin, Sibutramine | 20 RUB | -- |
| Dianormet | -- | 19 UAH |
| Diaformin metformin | -- | 5 UAH |
| Metformin metformin | 13 RUB | 12 UAH |
| Tshuaj Metformin sandoz metformin | -- | 13 UAH |
| Siofor | 208 rub | 27 UAH |
| Formin metformin hydrochloride | -- | -- |
| Emnorm EP Metformin | -- | -- |
| Megifort Metformin | -- | 15 UAH |
| Tshuaj hlau Metformin | -- | 20 UAH |
| Tshuaj Metamin SR Metformin | -- | 20 UAH |
| Tefor metformin | -- | -- |
| Glycometer | -- | -- |
| Glycomet SR | -- | -- |
| Tshuaj nyob | 37 RUB | -- |
| Metformin Canon metformin, ovidone K 90, pob kws hmoov txhuv, crospovidone, magnesium stearate, talc | 26 RUB | -- |
| Insuffor metformin hydrochloride | -- | 25 UAH |
| Metformin-teva metformin | 43 txhuam | 22 UAH |
| Diaformin SR metformin | -- | 18 UAH |
| Mepharmil Metformin | -- | 13 UAH |
| Metformin Ua liaj ua teb Metformin | -- | -- |
Cov npe saum toj no ntawm cov yeeb tshuaj analogues, uas qhia metfogamma hloov chaw, yog qhov tsim nyog tshaj plaws vim tias lawv muaj tib cov tshuaj sib luag thiab sib luag ua ke raws li kev taw qhia rau kev siv
Sib txawv muaj pes tsawg leeg, tuaj yeem ua ke nyob rau hauv kev taw qhia thiab cov qauv ntawm daim ntawv thov
| Npe | Nqe hauv Lavxias | Nqe hauv Ukraine |
|---|---|---|
| Avantomed rosiglitazone, metformin hydrochloride | -- | -- |
| Glibenclamide Glibenclamide | 30 RUB | 7 UAH |
| Maninyl Glibenclamide | 54 rub | 37 UAH |
| Glibenclamide-Health Glibenclamide | -- | 12 UAH |
| Glyurenorm glycidone | 94 rub | 43 UAH |
| Bisogamma Glyclazide | 91 rub | 182 UAH |
| Glidiab Glyclazide | 100 tshiav | 170 UAH |
| Lawj Xeeb MR | -- | 92 UAH |
| Kev kuaj mob mr Gliclazide | -- | 15 UAH |
| Glidia MV Gliclazide | -- | -- |
| Glykinorm Gliclazide | -- | -- |
| Gliclazide Gliclazide | 231 rub | 44 UAH |
| Glyclazide 30 MV-Indar Glyclazide | -- | -- |
| Glyclazide-Kev Noj Qab Haus Huv Gliclazide | -- | 36 UAH |
| Glioral Glyclazide | -- | -- |
| Kev kuaj mob Gliclazide | -- | 14 UAH |
| Diazide MV Gliclazide | -- | 46 UAH |
| Osliklid Gliclazide | -- | 68 UAH |
| Diadeon gliclazide | -- | -- |
| Glyclazide MV Gliclazide | 4 RUB | -- |
| Amaril | 27 RUB | 4 UAH |
| Glemaz glimepiride | -- | -- |
| Glian glimepiride | -- | 77 UAH |
| Glimepiride Glyride | -- | 149 UAH |
| Glimepiride diapiride | -- | 23 UAH |
| Thaj neeb | -- | 12 UAH |
| Glimax glimepiride | -- | 35 UAH |
| Glimepiride-Lugal glimepiride | -- | 69 UAH |
| Av nplaum glimepiride | -- | 66 UAH |
| Diabrex glimepiride | -- | 142 UAH |
| Meglimide glimepiride | -- | -- |
| Melpamide Glimepiride | -- | 84 UAH |
| Perinel glimepiride | -- | -- |
| Glempid | -- | -- |
| Raug Tsim | -- | -- |
| Glimepiride glimepiride | 27 RUB | 42 UAH |
| Glimepiride-Teva glimepiride | -- | 57 UAH |
| Glimepiride Canon glimepiride | 50 RUB | -- |
| Glimepiride Pharmstandard glimepiride | -- | -- |
| Dimaril glimepiride | -- | 21 UAH |
| Glamepiride diamerid | 2 RUB | -- |
| Amaryl M Limepiride Micronized, Metformin Hydrochloride | 856 rub | 40 UAH |
| Glibomet glibenclamide, metformin | 257 rub | 101 UAH |
| Glucovans glibenclamide, metformin | 34 RUB | 8 UAH |
| Dianorm-m Glyclazide, Metformin | -- | 115 UAH |
| Dibizid-m glipizide, metformin | -- | 30 UAH |
| Douglimax glimepiride, metformin | -- | 44 UAH |
| Duotrol glibenclamide, metformin | -- | -- |
| Gluconorm | 45 rub | -- |
| Glibofor metformin hydrochloride, glibenclamide | -- | 16 UAH |
| Avandamet | -- | -- |
| Avandaglim | -- | -- |
| Janumet metformin, sitagliptin | 9 RUB | 1 UAH |
| Velmetia metformin, sitagliptin | 6026 rub | -- |
| Galvus Met vildagliptin, metformin | 259 RUB | 1195 UAH |
| Tripride glimepiride, metformin, pioglitazone | -- | 83 UAH |
| Comboglize XR metformin, saxagliptin | -- | 424 UAH |
| Comboglyz Prolong metformin, saxagliptin | 130 rub | -- |
| Gentadueto linagliptin, metformin | -- | -- |
| Vipdomet metformin, alogliptin | 55 RUB | 1750 UAH |
| Sinjardi empagliflozin, metformin hydrochloride | 240 rub | -- |
| Voglibose Oxide | -- | 21 UAH |
| Glutazone pioglitazone | -- | 66 UAH |
| Dropia Sanovel pioglitazone | -- | -- |
| Januvia sitagliptin | 1369 rub | 277 UAH |
| Galvus vildagliptin | 245 RUB | 895 UAH |
| Onglisa saxagliptin | 1472 RUB | 48 UAH |
| Nesina alogliptin | -- | -- |
| Vipidia alogliptin | 350 rub | 1250 UAH |
| Trazhenta linagliptin | 89 rub | 1434 UAH |
| Lixumia lixisenatide | -- | 2498 UAH |
| Guarem Guar cob | 9950 rub | 24 UAH |
| Insvada repaglinide | -- | -- |
| Novonorm Repaglinide | 30 RUB | 90 UAH |
| Cov Chaw Tshaj Tawm Repaglinide | -- | -- |
| Baeta Exenatide | 150 rub | 4600 UAH |
| Baeta Ntev Exenatide | 10248 rub | -- |
| Viktoza liraglutide | 8823 rub | 2900 UAH |
| Saxenda liraglutide | 1374 rub | 13773 UAH |
| Forksiga Dapagliflozin | -- | 18 UAH |
| Forsiga Dapagliflozin | 12 RUB | 3200 UAH |
| Invocana canagliflozin | 13 RUB | 3200 UAH |
| Jardins Empagliflozin | 222 RUB | 566 UAH |
| Trulicity Dulaglutide | 115 RUB | -- |
Yuav ua li cas thiaj nrhiav tau qhov pheej yig tshuaj ntawm cov tshuaj kim?
Txhawm rau kom pom qhov pheej yig cov khoom sib piv rau cov tshuaj, cov dav dav lossis cov lus sau, ua ntej txhua yam peb pom zoo kom them sai sai rau qhov muaj pes tsawg leeg, uas yog rau tib cov tshuaj nquag thiab qhia tau rau kev siv. Cov tshuaj sib xyaw zoo ib yam ntawm cov tshuaj yuav qhia tau tias cov tshuaj cuam tshuam nrog cov tshuaj, kws tshuaj sib npaug lossis chaw muag tshuaj. Txawm li cas los xij, tsis txhob hnov qab txog qhov ua tsis muaj zog ntawm cov tshuaj uas zoo sib xws, uas tuaj yeem cuam tshuam kev nyab xeeb thiab ua haujlwm. Tsis txhob hnov qab txog cov lus qhia ntawm cov kws kho mob, kev noj tshuaj rau nws tus kheej tuaj yeem tsim kev puas tsuaj rau koj kev noj qab haus huv, yog li nco ntsoov sab laj nrog koj tus kws kho mob ua ntej siv cov tshuaj.
Cov lus qhia Metfogamma
METFOGAMMA® (METFOGAMMA) metformin Cov Sawv Cev: WERVAG FARMA GmbH thiab Co.KG 10 pcs. - hlwv (12) - pob khoom los ntawm cardboard.
Tshuaj, zaj duab xis-txheej dawb, oblong, nrog ib kab ntawm pob txha lov.
1 tab metformin hydrochloride 850 mg
Cov neeg siv: methylhydroxypropyl cellulose, povidone, magnesium stearate, titanium dioxide (E171), macrogol 6000.
10 Pcs - blister packs (3) - pob ntawv ntawm cardboard. 10 Pcs - hlwv pob (12) - pob khoom los ntawm cardboard.
TSO CAI №№:
- tab. zaj duab xis txheej, 850 mg: 30 lossis 120 pcs. - P No. 013816 / 01-2002, 03/12/02
- tab. zaj duab xis txheej, 500 mg: 30 lossis 120 pcs. - P No. 014463 / 01-2002, 10.16.02
Qhov ncauj tshuaj hypoglycemic los ntawm cov pab pawg biguanide. Nws inhibits gluconeogenesis nyob rau hauv daim siab, txo qhov nqus ntawm cov piam thaj los ntawm txoj hnyuv, txhim kho kev siv ntawm cov kua nplaum ntev, thiab tseem ua rau kev nkag siab ntawm cov ntaub so ntswg mus rau insulin. Nws tsis cuam tshuam qhov zais cia ntawm insulin los ntawm β-hlwb ntawm tus txiav.
Lowers triglycerides, LDL.
Stabilizes lossis txo qhov hnyav lub cev.
Nws muaj cov nyhuv fibrinolytic vim yog kev tsuj tawm ntawm cov nqaij plasminogen activator inhibitor.
Tom qab lub qhov ncauj tswj hwm, metformin yog nqus los ntawm cov hnyuv. Bioavailability tom qab noj cov qauv tshuaj yog 50-60%. Cmax tom qab kev tswj hwm ntawm qhov ncauj tau tiav tom qab 2 teev.
Nws xyaum tsis khi rau cov plasma protein. Nws accumulates nyob rau hauv salivary qog, nqaij, mob siab, thiab ob lub raum.
Nws tawm hauv cov zis tsis hloov pauv. T1 / 2 yog 1.5-4.5 teev.
Pharmacokinetics hauv cov chaw kuaj mob tshwj xeeb
Nrog kev ua haujlwm tsis zoo hauv lub raum, tsub zuj zuj ntawm cov tshuaj yog ua tau.
- hom 2 mob ntshav qab zib mellitus (non-insulin-dependant) yam tsis muaj ketoacidosis (tshwj xeeb tshaj yog rau cov neeg mob rog rog) nrog rau kev kho mob tsis muaj txiaj ntsig.
CEEV HOM
Teeb ntawm tus kheej, noj mus rau hauv tus account theem ntawm cov piam thaj hauv cov ntshav.
Thawj koob tshuaj txhua hnub feem ntau yog 0.5-1 g (Metfogamma 500) lossis 850 mg (Metfogamma 850). Ib qho kev nce zuj zus ntxiv hauv koob tshuaj yog muaj peev xwm ua raws li cov txiaj ntsig ntawm kev kho mob. Kev saib xyuas qhov tshuaj txhua hnub ua rau 1-2 g (Metfogamma 500) lossis 0.85-1.7 g (Metfogamma 850). Qhov siab tshaj plaws txhua hnub yog 3 g (Metfogamma 500) lossis 1.7 g (Metfogamma 850). Lub hom phiaj ntawm cov tshuaj nyob rau hauv cov koob tshuaj ntau dua tsis ua rau cov nyhuv ntawm txoj kev kho.
Qhov koob tshuaj txhua hnub ntau dua 850 mg yog pom zoo nyob rau hauv ob lub tshuaj (thaum sawv ntxov thiab yav tsaus ntuj).
Hauv cov neeg mob laus, cov koob tshuaj pom zoo yuav tsum tsis pub tshaj 850 mg / hnub.
Cov ntsiav tshuaj yuav tsum tau noj nrog zaub mov ua ke, ntxhua nrog ib qho me me ntawm cov kua (ib khob dej).
Cov tshuaj yog npaj rau kev siv sijhawm ntev.
Tej yam tsis zoo
Los ntawm lub plab zom mov: xeev siab, ntuav, mob plab, raws plab, tsis qab los noj mov, tsis qab los noj mov, yog xim hlau hauv lub qhov ncauj (raws li txoj cai, kev txiav tsis kho yuav tsis tas, thiab cov tsos mob ploj mus lawv tus kheej tsis tas hloov cov tshuaj ntawm cov tshuaj). Qhov zaus thiab qhov mob ntawm cov kev mob tshwm sim tuaj yeem txo nrog qhov nce zuj zus ntawm qhov koob tshuaj metformin.
Los ntawm cov kab ke endocrine: hypoglycemia (thaum siv tsis tas).
Los ntawm ib sab ntawm cov metabolism: hauv qee qhov tsawg - lactic acidosis (yuav tsum tsis ua haujlwm ntawm kev kho mob), nrog kev siv ntev - B12 hypovitaminosis (malabsorption).
Los ntawm cov kab mob hemopoietic: qee kis - megaloblastic anemia.
Kev ua xua rau: xoo pob khaus.
TSWJ SIB LWM
- uas ketoacidosis, mob ntshav qab zib precoma, coma,
- Mob raum tsis zoo,
- lub plawv thiab ua pa tsis ua haujlwm,
- mob theem ntawm myocardial infarction,
- mob kev sib tsoo cerebrovascular,
- kev haus cawv ntev ntev thiab lwm yam mob uas yuav ua rau kev txhim kho cov mob tuag tes tuag taw,
- lactic acidosis thiab keeb kwm ntawm nws,
- lactation (pub niam mis),
- Hypersensitivity rau cov tshuaj.
Cev xeeb tub thiab lactation
Cov tshuaj yog contraindicated rau kev siv thaum cev xeeb tub thiab thaum lactation (pub niam mis).
COV LUS QHIA TSHWJ XEEB
Kev siv cov tshuaj tsis raug pom zoo rau cov mob sib kis mob hnyav, ua kom dhau los ntawm cov kab mob sib kis thiab mob ntawm tus mob, raug mob, mob phais mob hnyav, thaum insulin kho yog qhia.
Cov tshuaj tsis tau noj ua ntej kev phais mob thiab hauv 2 hnub tom qab lawv tau ua.
Kev siv Metfogamma tsis pom zoo tsawg kawg 2 hnub ua ntej thiab 2 hnub tom qab xoo hluav taws xob los yog xoo hluav taws xob los ntawm kev siv tshuaj tiv thaiv.
Kev siv cov tshuaj tsis pom zoo rau cov neeg mob rau kev noj zaub mov noj nrog kev txwv hauv caloric kom tsawg (tsawg dua 1000 kcal / hnub).
Nws tsis pom zoo kom siv cov tshuaj rau cov neeg laus dua 60 xyoo uas ua haujlwm lub cev hnyav (vim tias qhov no cuam tshuam nrog kev pheej hmoo ntawm cov kab mob lactic acidosis).
Thaum lub sijhawm siv cov tshuaj, cov ntsuas raum kev ua haujlwm yuav tsum raug saib xyuas. Tsawg kawg 2 zaug hauv ib xyoos, nrog rau qhov pom ntawm myalgia, lub lactate cov ntsiab lus hauv cov ntshav yuav tsum txiav txim siab.
Metfogamma tuaj yeem siv ua ke nrog sulfonylurea derivatives los yog insulin, thiab tshwj xeeb tshaj yog saib xyuas cov ntshav qabzib ntau yuav tsum muaj.
OVERDOSE
Cov tsos mob: tuag taus lactic acidosis yuav tsim. Qhov ua rau kev txhim kho ntawm cov kab mob lactic acid tuaj yeem tseem yog kev ruaj khov ntawm cov tshuaj vim tias lub cev ua haujlwm tsis zoo. Cov tsos mob ua ntej tshaj plaws ntawm tus kab mob lactic acidosis yog xeev siab, ntuav, raws plab, txo qis lub cev kub, mob plab, mob nqaij, yav tom ntej yuav muaj kev ua pa ntxiv, kiv taub hau, tsis meej pem thiab tsis nco qab.
Kev Kho Mob: yog tias muaj cov cim ntawm cov kab mob lactic acidosis, kev kho mob nrog Metfogamma yuav tsum tau nres tam sim ntawd, tus neeg mob yuav tsum tau mus pw hauv tsev kho mob sai thiab, tau txiav txim siab qhov concentration ntawm lactate, paub meej tias txoj kev kuaj mob. Hemodialysis siv tau zoo tshaj plaws rau kev tshem tawm lactate thiab metformin tawm hauv lub cev. Yog tias tsim nyog, nqa tawm cov kev kho mob. Nrog cov kev kho ua ke nrog sulfonylureas, cov ntshav qog ntshav qab zib yuav ua mob.
KEV TXHAWB
Nrog rau kev siv tib lub sijhawm nrog sulfonylurea derivatives, acarbose, insulin, NSAIDs, MAO inhibitors, oxytetracycline, ACE inhibitors, clofibrate, cyclophosphamide, beta-blockers, nws muaj peev xwm nce hypoglycemic nyhuv ntawm metformin.
Nrog rau kev siv tib lub sijhawm nrog GCS, tshuaj tiv thaiv qhov ncauj, epinephrine (adrenaline), sympathomimetics, glucagon, cov thyroid hormones, thiazide thiab loopback diuretics, phenothiazine derivatives, nicotinic acid derivatives, txo qis hauv cov nyhuv hypoglycemic ntawm metformin yog ua tau.
Cimetidine qeeb kev tshem tawm ntawm metformin, uas ua rau muaj kev pheej hmoo ntawm lactic acidosis.
Metformin tej zaum yuav ua rau cov tshuaj anticoagulants tsis muaj zog (coumarin derivatives).
Nrog rau kev tswj hwm ua ke nrog ethanol, txoj kev txhim kho ntawm cov kab mob lactic acidosis yog ua tau.
