Formin lossis metformin
Muaj ntau cov generics ntawm cov tshuaj Glucofage. Hauv Lavxias, ib qho piv txwv yog Formetin thiab Metformin. Los ntawm txoj kev txiav txim ntawm lub zog lawv yog tib yam.
Cov tshuaj no yog rau cov neeg mob ntshav qab zib. Lawv muaj cov sib sau ua ke zoo sib xws thiab muaj feem ntsig txog hom tshuaj txo suab thaj. Lawv tuaj yeem tau yuav nrog cov kws kho mob xaj. Qhov twg zoo dua ntawm cov tshuaj, cov kws kho mob txiav txim siab, tsom mus rau qhov xwm txheej, tshuaj ntsuam thiab tshuaj ntsuam.
Muaj cov ntsiav tshuaj daim ntawv tso tawm. Cov tshuaj lom neeg tseem ceeb hauv qhov muaj pes tsawg leeg yog qhov sib xyaw ntawm tib lub npe. Muaj nyob hauv cov tshuaj ntau npaum 500 thiab 850 mg.
Metformin muaj cov tshuaj tseem ceeb ntawm tib lub npe.
Cov tshuaj yog nyob rau qeb ntawm biguanides. Cov tshuaj muaj txiaj ntsig ntawm cov tshuaj tau tshwm sim los ntawm kev txwv tsis pub muaj cov piam thaj nyob rau hauv daim siab thiab txo nws txoj kev nqus hauv cov hnyuv. Cov tshuaj tsis cuam tshuam rau cov txheej txheem ntawm cov tshuaj insulin ntau lawm hauv cov txiav, yog li tsis muaj kev pheej hmoo ntawm kev tiv thaiv hypoglycemic.
Cov tshuaj muaj cov txiaj ntsig zoo ntawm lub plawv hlab plawv, tiv thaiv kev txhim kho angiopathy mob ntshav qab zib.
Nrog rau kev tswj hwm qhov ncauj ntawm cov tshuaj, qhov siab tshaj plaws ntawm lub ntsiab tseem ceeb hauv cov ntshav tshwm sim tom qab 2.5 teev. Qhov nqus tau ntawm cov khoom txuas nres 6 teev tom qab noj tshuaj ntsiav. Kev tshem tawm ib nrab-lub neej ntawm cov khoom yog li 7 teev. Bioavailability muaj txog li 60%. Nws tawm hauv cov zis.
Kev ntsuas rau siv Metformin - ntshav qab zib mellitus ntawm hom thawj thiab thib ob. Cov tshuaj yog kws kho ua ib qhov txuas rau kev kho tshuaj insulin thiab kev siv lwm yam tshuaj, vim tias kev sib txuam tshuaj tau pom tias muaj txiaj ntsig zoo. Metformin kuj tseem yog qhov khoom siv tseem ceeb thaum kho mob.
Cov tshuaj yog siv rau kev rog, yog tias koj xav tswj cov qib ntawm cov piam thaj hauv cov ntshav, qhia tias kev noj zaub mov tsis muaj txiaj ntsig zoo. Lwm txoj kev kho mob tuaj yeem kho rau kev kuaj mob polycystic ovary, tab sis hauv qhov no, cov tshuaj tsuas yog siv nyob rau hauv kev saib xyuas ntawm tus kws kho mob.
Cov tshuaj muaj nyob rau hauv daim ntawv ntawm oval dawb ntsiav tshuaj. Lub hauv paus tseem ceeb ua ke yog metformin.
1 ntsiav tshuaj muaj 500, 850 thiab 1000 mg ntawm qhov tshuaj. Cov tshuaj yog npaj rau kev siv qhov ncauj.
Cov tshuaj tau tawm rau cov neeg uas muaj ntshav qab zib hom 2 thaum kev noj zaub mov tsis pab. Cov tshuaj siv kuj yog siv rau qhov poob phaus. Kev sib xyaw ua ke nrog kev kho mob insulin.
Dab tsi yog qhov sib txawv
Qhov sib txawv ntawm Metformin thiab Formmetin tsuas yog nyob rau ntawm excipients nyob rau hauv qhov muaj pes tsawg leeg ntawm cov ntsiav tshuaj. Ob qho khoom lag luam muaj povidone, magnesium stearate, croscarmellose sodium, dej. Tab sis Metformin tseem muaj cov tshuaj pleev cov kua roj gelatinized thiab microcrystalline cellulose.
Cov ntsiav tshuaj muaj cov plhaub ntim zaj duab xis, uas muaj talc, sodium fumarate, dyes.
Thaum muas tshuaj, nws yog ib qho tsim nyog yuav tsum them sai sai rau cov ntsiab lus ntawm cov tshuaj tiv thaiv pabcuam: qhov tsawg dua lawv yuav yog, zoo dua.
Uas yog pheej yig dua
Rau ob qho tshuaj, cov tuam ntxhab yog cov tuam txhab xws li Canon, Richter, Teva, thiab Ozone.
Kev noj tshuaj ntawm cov tshuaj nquag hauv ib ntsiav tshuaj yog 500, 850 thiab 1000 mg txhua. Ntawm tus nqi, ob Metformin thiab Formmetin nyob rau yuav luag tib qeb: thawj tuaj yeem yuav hauv Lavxias ntawm tus nqi kwv yees li 105 rubles rau pob khoom ntawm 60 ntsiav tshuaj, thiab rau qhov thib ob, tus nqi yuav yog li 95 rubles.
Dab tsi yog qhov zoo dua metformin lossis formin
Hauv ob qho tshuaj, cov tshuaj ua haujlwm tseem ceeb yog tib yam khoom - metformin. Hauv qhov no, cov nyhuv ntawm tshuaj yog tib yam. Ntxiv mus, cov nyiaj no yog sib pauv hloov tau.
Tsuas yog cov kws kho mob koom nrog tuaj yeem txiav txim siab cov tshuaj twg zoo rau txhua tus neeg mob, nyob ntawm qhov xwm txheej.
Hauv qhov xwm txheej no, hnub nyoog, tus yam ntxwv ntawm lub cev, qhov xwm txheej dav dav ntawm tus neeg mob, daim ntawv thiab qhov mob hnyav ntawm cov kab mob pathology raug coj los txiav txim siab.
Nrog ntshav qab zib
Ntawm cov ntshav qab zib ntawm thawj hom, thaum muaj kev ua tiav lossis ib feem ntawm kev ua txhaum kev tsim kho ntawm cov tshuaj insulin, Metformin thiab Formmetin tau siv los txo cov tshuaj ntau npaum li cas tom qab, ntxiv kev kho tshuaj hormones, hloov mus rau cov qauv tshiab ntawm insulin (kom muaj kev nyab xeeb nyob rau lub sijhawm no), thiab tseem tiv thaiv kev rog.
Ntawm ntshav qab zib ntawm yam thib ob, cov tshuaj yuav tsum tau noj ntau dua. Lawv txhim kho cov kev mob thoob plaws ntawm tus neeg mob nrog cov nqaij tsis zoo uas muaj peev xwm ua rau cov tshuaj insulin. Ua tsaug rau cov kev txhais tau no, qhov ntxim nyiam ntawm kev muaj teeb meem ntawm ntshav qab zib yog txo.
Kev Ntsuam Xyuas Rau Neeg Mob
Sergey, 38 xyoo, Moscow: “Ntsuas ntshav qab zib hom 2 tau kuaj pom. Kuv tau noj cov tshuaj Metformin txuas nrog cov tshuaj insulin rau ib xyoos. Cov cuab yeej pabcuam pab txhawm rau txo cov ntshav qab zib. Kuv txaus siab txog cov tshuaj, tsis muaj kev phiv tshuaj. "
Irina, hnub nyoog 40 xyoo, Kaluga: “Cov tshuaj muaj tau raws li kws kho mob hais. Qab zib yog qhov qub, tab sis muaj qhov teeb meem nrog kev rog dhau los. Nyob rau hauv tib, Kuv hloov mus rau ib tug qis-carb kev noj haus. Txij thaum pib ntawm txoj kev kho kom zoo li ntawd twb tau tswj kom yuag dhau ntawm 11 kg. Cov tawv nqaij mob tau zoo tuaj lawm. ”
Ntawm ntshav qab zib hom 2, cov tshuaj uas nug txog yuav tsum tau noj ntau dua.
Kev tshuaj xyuas ntawm cov kws kho mob txog Metformin thiab Formmetin
Maxim, tus kws kho mob endocrinologist, 38 xyoo, St. Petersburg: “Kuv xav txog Metformin yog ib qho tshuaj zoo rau kev kho mob ntawm pathologies ntawm endocrine system (ntshav qab zib mellitus, kev cuam tshuam ntawm cov metabolism metabolism.). Tab sis tib lub sijhawm, Kuv ib txwm ceeb toom kuv cov neeg mob txog kev phiv los sis uas muaj. Cov tshuaj no siv tau ob leeg ntawm nws tus kheej thiab hauv kev sib xyaw ua ke. "
Metformin thiab formin - lus piav qhia thiab nqis tes ua
Cov Tshuaj Tshuaj Metformin thiab Formmetin yog qhov ncauj tshuaj hypoglycemic (hypoglycemic), yog los ntawm biguanides. Ob qho tshuaj noj tshuaj uas tsim hauv tebchaws Russia thiab feem ntau muab tshuaj rau cov neeg mob ntshav qab zib.
Cov tshuaj muaj tshuaj nyob hauv cov tshuaj nquag - metformin (metformin hydrochloride).
Tus nqi ntawm cov tshuaj kuj tseem nyob rau hauv tib nqe nqi - Formmetin tus nqi 95 rubles / 60 ntsiav tshuaj, tus nqi ntawm Metformin yog 105 rubles rau tib lub pob. Cov kws tshaj lij pom zoo kom them sai sai rau cov neeg tsis paub qab hau - qhov tsawg dua lawv, qhov zoo dua yuav, qhov tsawg dua ntawm cov kev mob tshwm sim. Qhov uas ib txwm muaj rau ob daim ntawv yog:
- magnesium stearate,
- povidone
- dej
- croscarmellose sodium.
Metformin ntxiv rau muaj microcrystalline cellulose, pregelatinized hmoov txhuv nplej siab. Kev ua lag luam tshuaj ntawm ntau lub tuam txhab tau tsim cov tshuaj pleev xim raws li cov dyes, talc, sodium stearyl fumarate. Cov nyiaj ob leeg tau muab los ntawm cov tuam txhab xws li Teva, Richter, Canon, Ozone thiab lwm yam. Dosages - 0.5, 0.85, 1 g.
Vim tias tib cov nyhuv, cov tshuaj sib hloov pauv tau. Kev lees paub ua rau inhibition of gluconeogenesis nyob rau hauv lub siab hlwb, uas ua rau ib qho kev poob qis hauv cov ntshav qabzib. Tsis tas li, kev nqus ntawm cov suab thaj los ntawm kev mob plab hnyuv poob qis, kev siv ntawm cov piam thaj tiav hauv cov nqaij sib txawv nce ntxiv. Cov tshuaj muaj yuav luag tsis muaj kev cuam tshuam rau qhov nce hauv insulin rhiab heev hauv adipose nqaij, tab sis nws pab txhim kho qhov ntsuas no hauv cov leeg nqaij.
Kev ntsuas rau nkag
Txheeb xaiv qhov twg yog qhov zoo dua - Formmetin lossis Metformin - raws li cov cim taw qhia tsis pom zoo. Ob qho tshuaj yeeb tshuaj muaj tib lub hom phiaj thiab coj hauv cov tshuaj zoo sib xws. Hauv hom ntshav qab zib hom 1, uas tshwm sim nrog kev ua tiav lossis ib feem ntawm kev tsim cov tshuaj insulin, lawv xav tau rau cov hom phiaj no:
- insulin koob txo qis
- tshuaj insulin pab,
- lub sijhawm ntawm kev hloov mus rau cov ntaub ntawv tshiab ntawm insulin (rau kev nyab xeeb vim li cas),
- Kev tiv thaiv hnyav.
Ntawm hom ntshav qab zib hom 2, metformin thiab formin yuav tsum txhaj ntau dua. Txij li qhov rhiab heev ntawm cov hlwb rau cov tshuaj insulin yog qhov muaj peev xwm ua rau muaj hom mob no, cov tshuaj yuav txhim kho nws kom zoo. Raws li qhov tshwm sim, qhov ntxim nyiam yuav muaj teeb meem tsawg dua. Cov tshuaj kho yog muab rau kev noj haus tsis txaus, ntxiv rau kev noj haus, rau qhov poob phaus. Tshuaj yog qhia tshwj xeeb rau cov rog loj.
Tshuaj nyob rau hauv parallel txo txo qis ntawm triglycerides thiab roj nyob rau hauv cov ntshav.
Ntxiv nrog rau qhov tshwm sim zoo rau lipid metabolism, metformin tseem tuaj yeem tiv thaiv cov ntshav txhaws ntawm kev ua haujlwm. Nws suppresses tshwj xeeb cov protein uas txhim kho coagulation ntshav. Qhov no pab txo qis kev pheej hmoo ntawm mob stroke, lub plawv nres.
Cov lus qhia txog tshuaj
Haus cov ntsiav tshuaj yam tsis yog txhawm, zom kom huv, nrog dej (kom txaus). Kev txais tos yog tom qab noj mov, lossis thaum noj zaub mov. Tus naj npawb ntawm cov koob tshuaj tau nce nyob rau qhov mob hnyav ntawm cov ntshav qab zib. Koj tuaj yeem siv cov tshuaj kho mob monotherapy, hauv kev sib txuas ua ke nrog lwm cov tshuaj ntawm tib lub sawv.
Cov lus pom zoo rau cov tshuaj ntau npaum li cas hauv qab no:
- thaum pib kho - 1-1.5 g / hnub, faib los ntawm cov naj npawb xav tau ntawm cov koob tshuaj (feem ntau 3),
- tom qab ib lub lis piam lossis ob lub lis piam, koj tuaj yeem nce cov nyiaj tshwj xeeb raws li qhov xav tau ntawm cov piam thaj hauv qab,
- yog tias koj nce lub koob tshuaj rau qeeb, nws yuav txhim kho kev kam rau ua, ua rau muaj teeb meem tsawg dua ntawm txoj hnyuv,
Cov tshuaj yuav tuaj yeem ua qaug dej nrog cov tshuaj insulin. Hauv qhov xwm txheej no, qhov kev pib muab tshuaj qis dua - 500-850 mg / hnub, muab faib ua 3 koob. Qhov ntau npaum li cas ntawm cov tshuaj insulin yog xaiv los ntawm tus kws kho mob tshwj xeeb raws li kev kuaj ntshav. Ob qhov tshuaj no tuaj yeem muab rau cov menyuam yaus txij thaum 10 xyoo. Thawj qhov tshuaj yog 0.5 g / hnub ib zaug thaum yav tsaus ntuj, nrog zaub mov. Tom qab 2 lub lis piam, qhov tshuaj tau muab kho kho kom raug, qhov nyiaj ntau tshaj / hnub yog 2 g.
Cov kev thaiv tsis zoo thiab cov tshwm sim
Muaj ntau ntau yam contraindications rau cov tshuaj no, ntawm lawv muaj intolerance, kev tsis haum tshuaj, raws li zoo raws li ib tug xov tooj ntawm cov mob nyob rau hauv ib tug mob ntshav qab zib:
- ketoacidosis
- ua ntej coma
- mob raum tsis ua hauj lwm,
- lub cev tsis muaj dej txaus,
- mob hnyav
- poob siab mob
Cov yeeb tshuaj txwv tsis pub haus dej tom qab raug mob, hauv lub sijhawm tom qab kev ua haujlwm ntau. Hauv qhov no, nrog ib hom ntshav qab zib, lawv hloov mus rau insulin. Cov tshuaj tsis raug tshuaj nyob rau lub sijhawm cev xeeb tub, ua ntej thiab tom qab ua tiav cov kev tshawb fawb radiopaque (2 hnub).
Lawv raug kho nrog ceev faj hauv menyuam yaus txij li 10 xyoo, hauv cov neeg mob uas muaj hnub nyoog tshaj 65 xyoos, thaum lactation.
Kev siv tshuaj ntev nrog metformin yam tsis muaj kev cuam tshuam yuav cuam tshuam kev nqus ntawm cov vitamins B. Ntawm cov kev mob tshwm sim yog saj tsis meej, mob plab, xeev siab, ntuav, thiab zawv plab.
Qab los noj mov tuaj yeem yuav txo qis. Feem ntau, tag nrho cov kev cuam tshuam no ploj tom qab 14 hnub ntawm kev kho mob. Yog mob lub plab zom mov tshwm sim, cov ntsiav tshuaj yuav tsum noj nrog zaub mov. Hauv cov xwm txheej cais, kab mob siab (thim rov qab), kev tawm tsam ntawm daim tawv nqaij hloov pauv.
Analogs thiab dab tsi ntxiv koj yuav tsum paub?
Ntawm cov analogues muaj ib tug xov tooj ntawm cov tshuaj - txawv teb thiab domestic, uas nyob rau hauv cov muaj pes tsawg leeg muaj metformin los yog lwm cov tshuaj nquag nrog cov nyhuv hypoglycemic. Qee cov tshuaj yog cov tshuaj hormonal (piv txwv, raws li gliclazide):
Tshuaj | Muaj pes tsawg leeg | Nqe, rubles |
Siofor | Metformin | 280 |
Maninil | Glibenclamide | 170 |
Dibikor | Taurine | 340 |
Lawj xeeb | Gliclazide | 340 |
Glucophage Ntev | Metformin | 350 |
Glyformin | Metformin | 260 |
Galvus | Vildagliptin | 860 |
Thaum kho, nws yog ib qho tseem ceeb uas yuav tau nquag kuaj zis thiab ntshav kom ntsuas tau lub raum kev ua haujlwm. Txij li thaum lactic acidosis tsim nyob rau hauv ntau tus neeg mob thaum noj tshuaj, nws tseem yog qhov yuav tsum tau kuaj xyuas qhov muaj lactate hauv cov ntshav 1-2 zaug / xyoo (tib yam yuav tsum tau ua rau mob leeg). Nrog rau kev sib koom tes ntawm cov tshuaj insulin, kev tswj cov ntshav qab zib yog qhov tseem ceeb heev, nws yuav tsum ua txhua hnub. Txais tos nrog lwm tus neeg cov ntshav nrog yog qhov txaus ntshai tuaj yeem ua rau muaj piam thaj hauv qab zib. Yog tias qhov tsis muaj zog, tshee hnyo, tsaus muag, thiab lwm cov tsos mob ntawm tus mob ntshav qab zib tsawg tshwm sim, koj yuav tsum ua ntsuas sai sai tom tsev lossis sab laj nrog kws kho mob.