Gentamicin tshuaj pleev 0, 1%

Antimicrobial, tua cov kab mob antibacterial. Daim ntawv thov: kub hnyiab, qhov txhab, mob voos, ntxau.

Tus nqi kwv yees (thaum lub sijhawm luam tawm ntawm tsab xov xwm) los ntawm 33 rubles.

Hnub no peb yuav hais txog cov tshuaj pleev gentamicin. Cov tshuaj zoo li cas? Dab tsi pab? Yuav siv nws li cas thiab ua li cas cov tshuaj noj? Kuv puas tuaj yeem siv nws thaum cev xeeb tub, lactation thiab hauv menyuam yaus?

Yam tshuaj twg zoo

Ib qho tshuaj tua kab mob rau sab muaj zog.

Nws muaj cov antimicrobial zoo hauv kev kho mob ntawm daim tawv nqaij. Muaj nyob hauv pawg aminoglycoside, zoo rau qhov kev yeej ntawm daim tawv nqaij los ntawm cov kab mob gram-negative.

Cov nyhuv qis dua pom rau cov kab mob gram-zoo.

Tshuaj tua kab mob los kho tus mob thiab kis kab mob. Qhov muaj thiab qhov zoo ntawm cov tshuaj yog paub tseeb los ntawm kev tshuaj xyuas zoo.

Tso tawm daim ntawv thiab muaj pes tsawg leeg

Daim ntawv koob tshuaj - tshuaj pleev rau kev siv sab nrauv 0.1%: los ntawm daj mus rau xim dawb (hauv ib lub raj txhuas 15 g, hauv ib daim ntawv thawv 1 lub raj).

Txheej Txheem 1 g tshuaj pleev:

• cov tshuaj nquag yog gentamicin (nyob rau hauv daim ntawv ntawm gentamicin sulfate) - 0.001 g,
• kev nthuav dav: khoom roj av roj av paraffin, muag dawb paraffin.

Tso tawm daim ntawv, muaj pes tsawg leeg, ntim khoom

Nthuav ua daim ntawv ntau npaum ntawm 0.1% qab zib rau kev siv sab nraud. Lwm cov ntaub ntawv ntau ntawm gentamicin:

• qhov muag tee
• kev daws rau cov thawj coj intravenous,
• tshuaj txhaj tshuaj intramuscular,
• hmoov rau qhov kev npaj ntawm txhaj tshuaj tov.

Cov tshuaj nquag ntawm cov tshuaj pleev yog gentamicin sulfate nrog ntau npaum ntawm 0.001 g. Hygroscopic ntxeem tau hmoov ntau.

Txhawb nqa cov protein synthesized los ntawm cov kab mob, yog cov tshuaj tua kab mob hauv kev kho mob ntawm ntau yam kab mob.

Ntu cov khoom siv: cov roj ntsha tawv thiab muag muag.

Cov Tshuaj Hauv Tshuaj

Nws yog rau cov cim tshiab ntawm aminoglycosides.

Ua kom puas ntawm daim nyias nyias phab ntsa ntawm cov kab mob ua rau nws txoj kev tuag, tsis hais txog theem ntawm mitosis (faib).

Nws muaj peev xwm los ua ib qho kev sib xyaw nrog tRNA thiab mRNA, tiv thaiv kev tsim cov kab mob hauv cov kab mob ribosomal.

Tus rhuav tshem cytoplasm ntawm lub cell, vim qhov tshwm sim ntawm kev tshwm sim rau gentamicin sulfate, tso tseg tsis ua ke cov kab mob protein.

Zoo heev tiv thaiv cov kab mob gram-tsis zoo:

• salmonella
• shigella
• Escherichia coli,
• Cuam Tshuam
• pseudomonium
• enterobacteria.

Pathogens yog cov kab mob aerobic.

Hais txog qhov zoo ntawm cov kab mob gram ntawm kev kis tus kab mob, cov tshuaj pleev gentamicin tsis zoo:

• mob staph,
• kab mob streptococcal (qee yam kab mob).

Haum rau penicillin tsis kam ntawm lub cev, tab sis tsis muaj peev xwm rhuav tshem lub xovtooj ntawm phab ntsa ntawm microbes xws li neisseria, treponema thiab feem ntau anaerobes.

Cov Tshuaj Pharmacokinetics

Thaum muaj kev puas tsuaj rau cheeb tsam loj dua, siv rau saum npoo yog nqus sai sai.

Kev thov lub qab zib ntawm cov nqaij mos granulation ua rau kev nqus sai ntawm cov tshuaj. Gentamicin yuav luag tsis nqus los ntawm daim tawv nqaij sib txawv.

Nws yog tawm kom dhau los ntawm lub raum.

Cov lus qhia rau kev siv sab nraud gentamicin tshuaj pleev yog conventionally muab faib ua thawj cov laj thawj thiab rov mob lossis ntxiv:

• thawj cov kab mob ntawm daim tawv nqaij: furunculosis, sab nraud folliculitis, ib daim ntawv mob ntawm daim tawv nqaij qhib, mob pyoderma (suav nrog rau kev ua paug), paronychia,
• kev kis mob thib ob: cov kab mob ntawm daim tawv nqaij tawv tawv, cov tawv nqaij ua paug daj, mob nqaij daim tawv nqaij, ua rau lub cev nqaij tawv, ua kom mob rau cov tawv nqaij,
• kub lug txiav
• nto abrasions,
• daim tawv nqaij abscesses
• hlwv rau ntawm daim tawv nqaij,
• sib sib zog kho cov tawv nqaij mob,
• inflamed postoperative nti,
• kub hnyiab ntawm kuv thiab II degree,
• kab tom.

Gentamicin Tshuaj pleev pleev:

Nws muaj peev xwm los kho cov ntswg qhov ntswg nrog mob staph ntxiv.

Yuav thov li cas

Cov khoom lag luam yog thov superficially, thov ib txheej nyias nyias rau lub qhov txhab uas yav tas los ntxuav ntawm cov nplawm thiab necrotic pawg. Kev nyuag tsis pom zoo.

Thov 2-3 zaug ib hnub. Cov txheej yuav tsum yog nyias. Txog kev hlawv, siv txog li 3 zaug hauv ib asthiv nyob rau hauv daim ntawv ntawm zaws los ntawm cov khoom.

Qhov siab tshaj plaws niaj hnub noj rau cov qhov txhab dav dav yuav tsum tsis pub ntau tshaj 200 mg. Lub chav kawm ntawm kev kho mob yog 14 hnub.

Kev pom zoo rau kev siv

• nyob rau hauv cov ntaub ntawv ntawm daim tawv nqaij mob (pob txuv, ntxau, ntxau), thov taw tes 2 zaug hauv ib hnub,
• boils yog them nrog ib txheej nyias nyias, tawm kom txog thaum nqus tau,
• gentamicin yog thov rau cov tawv nqaij qhuav, yog li ntawd, nrog exudative
• Cov qhov txhab zais zis ntxuav nrog cov tshuaj chlorhexidine, furatsilina lossis hydrogen peroxide. Kev kub nyhiab tsis tuaj yeem ntxuav nrog peroxide!

Sab sij huam

Tuaj yeem nrog cov kev tawm tsam hauv zos. Cov kev mob tshwm sim suav nrog: khaus, hlawv, hyperemia, edema.

Hauv cov teeb meem loj: angioedema.

Ntawm ib feem ntawm cov ntshav tsim - nce ntau ntawm eosinophils thiab leukocytosis.

Nrog kev kho mob ntev ntev ntawm qhov chaw hlawv ntev tshaj plaws, cov nyhuv nephrotic lossis ototoxic yuav tshwm sim.

Kev kho mob ntawm kev tsis haum tshuaj tiv thaiv yog ua nrog antihistamines qhov ncauj tshuaj.

Cov Yuav Tsum Tau Ua

• hypersensitivity rau aminoglycosides,
• ib tug neeg intolerance,
• hnub nyoog siab heev
• cov me nyuam qis dua 3 xyoos,
• lub raum tsis ua hauj lwm zoo,

Cov kab mob ntawm cov kab mob parkinsonism, myasthenia gravis, kab mob botulism, thiab hnov ​​pob ntseg ntawm cov leeg tsis muaj zog yuav tsum siv tshuaj kom zoo.

Thaum cev xeeb tub

Txwv tsis pub nyob rau thawj thawj lub hlis thaum cev xeeb tub. Hauv II thiab III tsuas yog siv lus pom zoo los ntawm kws kho mob.

Gentamicin sulfate tuaj yeem muaj cov tshuaj lom rau hauv lub cev hauv plab, thaum nws hla ntawm hematoplacental teeb meem.

Yeeb tshuaj sib cuam tshuam

Kev kho nrog gentamicin ointment yuav tsum tsis txhob nrog cov tshuaj tua kab mob nrog streptomycin thiab florimycin. Poov tshuaj, sodium, magnesium, calcium txo cov kev ua ntawm cov tshuaj.

Tsis sib haum nrog heparin thiab acid tsis khov.

Siv nrog corticosteroids ua rau kom kho ntau ntxiv ntawm ob cov tshuaj.

Tus nqi nruab nrab ntawm cov tshuaj pleev gentamicin hauv ib lub tsev muag tshuaj yog 50-70 rubles. Nws tsis muaj qhov pheej yig tsis zoo, tab sis los ntawm cov kim:

• Gentamicin - Akos - 100-120 rubles - muaj tib yam khoom ua haujlwm nquag,
• Raws li cov lus pov thawj thiab kev siv: Supirocin - 360-770 rubles, Baneocin - txog 390 rubles, Syntomycin - txog 800 rubles,
• Cov tshuaj hormonal ua ke nrog gentamicin yog Belogent.

Tsis txhob txhuam

Tsis txhob siv rau cov menyuam yaus hnub nyoog qis dua 3 xyoos.

Nws yog txwv tsis pub hauv 1 hlis ntawm kev xeeb tub thiab thaum pub niam mis

Kev ntsuas rau siv

• thawj cov kab mob kis rau ntawm daim tawv nqaij thiab (lossis) cov nqaij mos ua rau muaj mob microflora: ua rau mob cov nqaij hauv lub cev, nqaij mos (nrog rau cov leeg tsis muaj zog), furunculosis, paronychia, sycosis, mob pob txuv,
• kev kis mob rau cov tawv nqaij thib ob: cov mob ua kom mob tawv nqaij (nrog rau seborrheic, tiv tauj thiab eczematous), cov kab mob kis tau rau lub cev muaj kab mob thiab kis ua mob rau daim tawv,
• muaj mob rau daim tawv nqaij ntawm ntau txoj kev ua haujlwm: mob (nrog rau sagging, phais), txiav, kub hnyiab (tsis yooj yim, II - IIIA degrees), mob kiav txhab (suav nrog varicose), kab tom,
• mob daim tawv nqaij ua qog thiab lub pob (tom qab qhib thiab hnoos tawm).

Cov lus qhia rau kev siv tshuaj pleev cov tshuaj pleev Gentamicin 0.1%: cov qauv thiab ntau npaum li cas

Gentamicin tshuaj pleev 0.1% yog siv rau sab nraud. Cov tshuaj siv rau hauv ib txheej txheej nyias mus rau thaj tsam ntawm daim tawv nqaij tom qab tshem tawm purulent thiab necrotic masses 2-3 zaug hauv ib hnub. Nrog cov qhov txhab txuas ntxiv ntawm daim tawv nqaij, qhov siab tshaj plaws txhua hnub koob tshuaj gentamicin yuav tsum tsis pub tshaj 200 mg, uas sib haum rau 200 g ntawm tshuaj pleev. Lub sijhawm tiv thaiv yog txiav txim los ntawm tus kws kho mob.

Noj ntau dhau

Txij li cov tshuaj muaj cov tshuab nqus qis, nws txoj kev siv ntau dhau tsis zoo.

Thaum muaj kev siv ntev ntev ntawm Gentamicin Ointment 0.1% hauv kev txhawb nqa ntau ntxiv, nrog rau cov qhov txhab ntawm daim tawv nqaij ntau dua, nephrotic (suav nrog rau azotemia, proteinuria) thiab ototoxic (kiv taub hau, tsis tshua muaj, hnov ​​lus tsis zoo), muaj kev ua haujlwm ntawm hepatic transaminases, hyperbilirubinemia, hloov cov roj ntsha sib xyaw hauv cov ntshav nruab nrog cev.

Cov lus qhia tshwj xeeb

Gentamicin tshuaj pleev 0.1% tsis yog siv rau daim ntawv thov rau cov leeg mos, nrog rau hauv qhov muag.

Nrog lub sijhawm ntev ntawm kev siv tshuaj pleev gentamicin, kev txhim kho ntawm kev ua tiav yog ua tau.

Thaum kho nrog cov tshuaj, Nws raug nquahu kom siv cov tshuaj tua kab mob, vim tias siv tshuaj pleev gentamicin tuaj yeem ua rau txoj kev loj hlob ntawm cov kab mob tiv thaiv kab mob rau cov tshuaj tua kab mob, suav nrog cov kab mob fungal. Hauv qhov no, xws li thaum mob tawv nqaij, rov qab ua xua, lossis rov kis tus kab mob dua, kev kho nrog tshuaj pleev gentamicin yuav tsum tsis ua ntxiv thiab kev kho tsim nyog yuav tsum tau nqa tawm.

Cov tshuaj tsis pom zoo rau siv nrog kev sib txig ib qho kev tswj hwm ntawm aminoglycoside tshuaj tua kab mob vim tias muaj kev pheej hmoo ntawm kev phiv tshuaj lom.

Yog tias tom qab 1 lub lis piam ntawm kev thov tshuaj pleev, kev kho mob tsis tuaj, nws yog qhov yuav tsum tau sab laj nrog cov kws tshaj lij.

Thaum muaj kev kho mob rau thaj chaw loj ntawm daim tawv nqaij, tshwj xeeb tshaj yog ncua sijhawm ntev, nrog rau yog tias nws yuav tsum tau thov rau ntawm cov tawv nqaij uas puas, kev ua kom lub cev muaj zog ntawm cov tshuaj tua kab mob muaj peev xwm nce ntxiv. Hauv cov xwm txheej no, tshwj xeeb tshaj yog nyob rau menyuam yaus, kev ceev faj yuav tsum ua kom tawm dag zog, vim tias qhov kev pheej hmoo ntawm cov kab mob thoob ntiaj teb muaj ntau ntxiv.

Thaum siv cov tshuaj nyob hauv thaj chaw mos, nws yog ib qho tsim nyog yuav tsum tau coj mus rau hauv tus account tias tshuaj pleev tuaj yeem ua rau txo qis ntawm lub zog ntawm cov hnab looj latex vim yog qhov muag dawb paraffin uas muaj nyob hauv nws, yog li txo cov txiaj ntsig.

Cev xeeb tub thiab lactation

Hauv thawj peb lub hlis thaum cev xeeb tub, 0.1% gentamicin ointment tsis pom zoo. Hauv kev txiav thib ob thiab thib peb, kev siv tshuaj pleev yog ua tau nyob rau hauv rooj plaub thaum kev cia siab rau cov poj niam muaj peev xwm dhau qhov kev pheej hmoo rau tus me nyuam hauv plab.

Hauv ib qho me me, gentamicin kis mus rau hauv niam cov kua mis. Vim tias tsis muaj qhov nqus ntawm cov tshuaj hauv txoj hnyuv, kev txhim kho cov kev mob tshwm sim thaum lub sijhawm pub niam mis tau muaj tsawg.

Tus nqi ntawm cov tshuaj pleev Gentamicin 0.1% hauv cov chaw muag tshuaj

Tus nqi kwv yees 0.1% Gentamicin tshuaj pleev yog kwv yees li 70 rubles rau ib lub raj ntawm 15 g.

Kev Kawm: Rostov State Medical University, tshwj xeeb "General Tshuaj".

Cov ntaub ntawv hais txog cov tshuaj raug muab dav dav, muab rau kev qhia tawm thiab tsis hloov chaw cov lus qhia. Kev siv tshuaj rau tus kheej yog qhov txaus ntshai rau kev noj qab haus huv!

Raws li kev tshawb fawb, cov poj niam uas haus ob peb khob npias lossis cawv txiv hmab ib lim tiam muaj feem ntau yuav muaj mob khees xaws mis.

Cov tib neeg uas tau noj tshais ua ntu zus feem ntau yog cov muaj rog.

Muaj 74 xyoo nyob hauv tebchaws Australian yawg James Harrison tau los ua neeg muab ntshav li 1,000 zaus. Nws muaj ib hom ntshav uas tsis tshua muaj, cov tshuaj tiv thaiv uas pab cov menyuam mos liab uas muaj ntshav tsawg txaus kom ciaj sia taus. Yog li, Australian thiaj cawm tau ntau txog ob lab tus menyuam.

Cov poj niam feem ntau muaj peev xwm tau txais kev lom zem ntau dua los ntawm kev xav txog lawv lub cev zoo nkauj hauv daim iav dua li ntawm kev sib deev. Yog li, cov poj niam, siv zog ua kom muaj kev sib haum xeeb.

Ntau lab tus kab mob tau yug, ciaj thiab tuag hauv peb lub plab. Lawv tuaj yeem pom tsuas yog txhawb nqa siab, tab sis yog tias lawv tuaj ua ke, lawv yuav haum rau hauv lub khob kas fes.

Nws tau siv los ua yawning enriches lub cev nrog oxygen. Txawm li cas los xij, qhov kev pom no tau nthuav dav. Cov kws tshawb fawb tau ua pov thawj tias yawning, ib tus neeg ua kom lub hlwb txias thiab txhim kho kev ua haujlwm.

Cov tshuaj hnoos "Terpincode" yog ib tus thawj coj hauv kev muag, tsis muaj vim tias nws muaj tshuaj.

Hauv tebchaws Askiv, muaj txoj cai lij choj raws li uas tus kws phais neeg tuaj yeem tsis kam ua haujlwm rau tus neeg mob yog tias nws haus luam yeeb lossis rog dhau. Ib tus neeg yuav tsum tso tawm tus cwj pwm tsis zoo, thiab tom qab ntawd, tej zaum, nws yuav tsis xav tau kev phais mob.

Tib neeg cov ntshav "khiav" los ntawm cov hlab ntsha hauv qab qhov siab, thiab yog tias nws txoj kev ncaj ncees tau ua txhaum, nws tuaj yeem tua txog 10 meters.

Lub siab yog qhov ua haujlwm hnyav tshaj plaws hauv peb lub cev. Nws qhov hnyav nruab nrab yog 1.5 kg.

Muaj ntau cov kev kho mob nthuav tawm heev, xws li kev siv khoom tsis nco qab ntawm cov khoom. Hauv plab ntawm ib tus neeg mob uas tau mob los ntawm tus txiv neej no, 2500 cov khoom txawv teb chaws tau pom.

Ntau cov tshuaj tau xub pib ua lag luam li tshuaj. Piv txwv li yeeb dawb, tau pib ua lag luam ua tshuaj hnoos. Thiab cocaine tau pom zoo los ntawm cov kws kho mob ua tshuaj loog thiab yog lub zog ntawm kev ua kom lub siab ntev.

Tus neeg noj tshuaj tiv thaiv kab mob feem ntau yuav rov qab muaj kev nyuaj siab. Yog tias ib tug neeg mob nrog kev nyuaj siab ntawm nws tus kheej, nws muaj txhua lub sijhawm tsis nco qab txog lub xeev no tas mus li.

Cov kws kho hniav tau tshwm sim tsis ntev los no. Rov qab rau hauv lub xyoo pua puv 19, nws yog lub luag haujlwm ntawm tus kws tu plaub hau kom rub tawm cov hniav mob.

Tus neeg muaj kev kawm paub tsis yooj yim rau cov kab mob hlwb. Cov kev txawj ntse ua haujlwm koom nrog kev tsim cov ntaub so ntswg ntxiv los txhawb rau cov neeg mob.

Raws li kev txheeb cais, kwv yees li 80% ntawm cov poj niam hauv Lavxias txom nyem mob los ntawm kab mob vaginosis. Raws li txoj cai, tus kab mob tsis kaj siab no tau nrog los ntawm dawb los yog txho outflows.

Cov chaw muag tshuaj ntawm cov tshuaj: yuav ua li cas cov tshuaj ua haujlwm, nws tsis tuaj yeem ua dab tsi?

Ua ntej koj kawm txog cov tshuaj tua kab mob hu ua "Gentamicin-Akos" (rau cov tshuaj pleev no yog tshuaj), tsim nyog kom nws paub nws zoo dua. Cov tshuaj yog xim daj-pob tshab, uas suav nrog cov khoom ntawm tib lub npe. Qhov gentamicin tivthaiv yog hais txog cov tshuaj tua kabmob aminoglycoside.

Cov tshuaj yog muaj peev xwm ua kom muaj cov kab mob bactericidal thiab tshem tawm cov kab mob microbial. Cov tshuaj muaj qhov pom dav ntawm qhov kev txiav txim. Nws sai sai rau cov kab mob hauv daim nyias nyias phab ntsa, tiv thaiv nws kev sib tov. Cuam ntau cov kab mob gram-zoo, thiab ntxiv rau yuav luag txhua yam gram-tsis zoo. Txawm hais tias nws ua tau zoo, Gentamicin-Akos tsis muaj peev xwm tshem tawm tus mob meningococcal, treponema, thiab qee yam kab mob staphylococcus. Anaerobic cov kab mob me me kuj tiv taus cov tshuaj no.

Cov lus qhia rau kev siv hais li cas: kev ntsuas thiab contraindications

Yog tias koj npaj siab siv tshuaj pleev pleev cov tshuaj pleev Gentamicin-Akos, cov lus qhia rau kev siv yuav qhia koj txog qhov kev xav tau no. Cov lej nchav sau cov tshuaj pab nrog. Ntawm cov ntsuas:

• cov kab mob ntawm daim tawv nqaij
• kev ua neeg lom zem pyoderma,
• furunculosis thiab sab nraum folliculitis,
• paronychia, sycosis,
• seborrheic dermatitis (mob),
• pob txuv
• mob voos voos uas ua tawm los ntawm cov leeg ntshav.

Tsis txhob siv cov tshuaj pleev nrog kev ua kom lub siab tsis zoo rau cov tshuaj nquag, neuritis ntawm cov khoom hnov. Mob raum tsis zoo, mob rwj, lactation thiab cev xeeb tub tseem ua mob tsis muaj mob.

Eczematous dermatitis: kev siv tshuaj pleev tua kabmob

Feem ntau cov neeg uas hu rau kws kho qhov muag nrog xoom xoo ntawm pob khaus hnov ​​cov kev kuaj mob no. Eczematous dermatitis yog kev tsis haum tshuaj, tshwm sim los ntawm daim tawv nqaij liab, txau thiab tsim cov hlwv me me. Yog hais tias tus kab mob tsis tau pib, ces txoj kev kho feem ntau tsis tas yuav siv tshuaj tua kab mob. Antihistamines, kho tshuaj pleev yog kho rau tus neeg mob.

Tab sis nws tseem tshwm sim tias cov npuas ua rau pib tawg lossis qhib los ntawm tus neeg mob nws tus kheej. Hauv qhov no, kev sib kis theem nrab tau tshwm sim. Hauv cov xwm txheej no, cov tshuaj "Gentamicin-Akos" yog tsim nyog kho.Vim li cas cov tshuaj pleev siv rau hauv cov kis zoo li no? Cov tshuaj muaj peev xwm tshem tawm cov kab mob sib xyaw nrog. Qhov kev txiav txim no yuav ceev kho. Siv cov tshuaj no rau sab nraud, ob zaug ib hnub. Yog tias siv tshuaj pleev ntxiv, tom qab ntawd koj yuav tsum mus so nruab nrab ntawm lawv.

Yuav Gentamicin-Akos pab nrog tus mob hu ua paronychia?

Kev kho cov kab mob periungual inflamed infering feem ntau yog nrog tshuaj tua kab mob. Qhov ua kom muaj tus kab mob tuaj yeem yog qhov sib txawv: kev kis kab mob los yog pwm, kev xwm txheej, hluav taws xob, kev ua tsis tau zoo, thiab lwm yam. Yog tias suppuration pib, uas ua rau paronychia, kev kho mob yuav tsum tsim nyog los ntawm kev siv tshuaj tua kab mob.

"Gentamicin-Akos" yog thov rau thaj tsam inflamed nyob rau hauv daim ntawv ntawm cov compress. Kev npaj ua ntej tuaj yeem qhib qhov rooj. Tab sis nws yog tsis yooj yim sua kom ntawm nws tus kheej nqa tawm li kev ntxias. Txhawm rau kom tsis txhob ua rau koj tus kheej tsis zoo, koj yuav tsum sab laj tus kws phais neeg. Tom qab cov txheej txheem, thov siv cov tshuaj nrog ib txheej nyias ntawm cov tawv nqaij ntawm cov tawv nqaij, txais ib feem ntawm daim tawv nqaij noj qab haus huv. Tso cev khaub ncaws uas tsis tsw lwj thiab muab cev ntiv tes tso. Qhov kev tsim no tsis tuaj yeem ntub. Koj yuav tsum hloov daim ntaub qhwv 3-4 zaug ib hnub.

Kev txheeb xyuas ntawm uas nws yuav nthuav kom paub cov neeg siv khoom

Cov neeg mob feem ntau nug lawv tus kheej: vim li cas tus kws kho mob tau sau tshuaj rau Gentamicin-Akos, vim li cas? Cov tshuaj pleev, thaum nws tig mus, tuaj yeem tiv thaiv ntau yam kab mob ntawm cov tawv nqaij. Raws li kev txheeb xyuas, feem ntau cov neeg siv khoom siv tshuaj tau los tua cov rwj thiab txawm tias mob ntxau ntawm lawv lub ntsej muag. Yog hais tias qhov mob tshwm sim los ntawm cov kab mob meej, ces cov tshuaj yuav pab koj. Cov tswv yim zoo yog tsim txog nws. Txog qee leej neeg, tshuaj tiv thaiv kab mob tau pab kho tus kab mob rhinitis (nrog rau siv cov ntswg).

Tab sis, zoo ib yam li lwm yam kev kho mob, muaj tshuaj tua kab mob thiab tsis zoo tshuaj xyuas. Qee cov neeg siv khoom tsis txaus siab ntawm cov tshuaj. Lawv tau hais tias cov roj pleev tsis tau pab lawv daws qhov teebmeem nkaus xwb, tabsis tseem ntxiv tau ntau lwm yam kev mob tsis zoo tas mus li. Feem ntau peb tab tom tham txog kev ua xua. Qhov no yog ib qho ntawm cov kev mob tshwm sim ntawm cov tshuaj. Yog tias nws tshwm sim, koj yuav tsum tau sab laj ib tus kws kho mob kom pab tswv yim.

Hloov ib txoj kev xaus

Los ntawm tsab xov xwm koj tau kawm txog dab tsi Gentamicin-Akos tshuaj pleev pab kho mob. Cov tshuaj muaj txiaj ntsig zoo rau kev tua cov kab mob ntawm daim tawv nqaij, suppurations, hlawv roj. Cov cuab yeej tseem siv los kho cov kab mob ocular. Txawm hais tias muaj tus yam ntxwv zoo thiab tau txais txiaj ntsig zoo ntawm cov tshuaj, tsis txhob ua phem rau nws.

Tsis txhob siv cov tshuaj pleev pleev yam tsis muaj kws kho mob sau. Nco ntsoov tias qhov tsis txaus siab ntawm kev kho tsis raug. Yog hais tias tus mob yog tshwm sim los ntawm ib tus kab mob fungal los yog tus kab mob, ces cov tshuaj yuav tsis pab koj. Ntxiv mus, nws yuav tua cov kab mob hauv ntuj, tsim kom muaj kev tiv thaiv zoo tshaj plaws rau kev ua tiav cov kab mob. Kho tau kom raug!

Puas txhawj xeeb txog tus mob prostatitis? Txuag txuas

Hauv kev sib txuas nrog qhov tshwm sim ntau dua ntawm cov kab mob ntawm daim tawv nqaij, kev xaiv cov tshuaj muaj ntau zuj zus tuaj, cov nyhuv ntawm kev tsom mus rau kev sib txuas ntawm ntau cov kab mob me. Ntawm cov tshuaj zoo heev, ib hom tshuaj xws li Gentamicin Ointment tau tshwm sim.

Cov tshuaj no tau txais txiaj ntsig hauv ntau tus neeg mob vim tias nws tus nqi kho mob loj, ua kom muaj zog. Peb yuav xav txog cov lus qhia niaj hnub no rau kev siv tshuaj pleev gentamicin rau menyuam yaus thiab cov neeg laus, nws cov analogues, cov nqi thiab tshuaj xyuas txog nws.

Cov yam ntxwv ntawm cov tshuaj

• Cov tshuaj nyob rau hauv kev txiav txim siab nrog kev siv sijhawm ntev yuav ua rau kev txhim kho ntawm cov kabmob ntawm cov kab mob pathogenic rau nws.
• Yog tias cov neeg mob mob raum tsis zoo siv cov tshuaj los kho thaj chaw loj ntawm daim tawv nqaij, cov nyhuv resorptive ua tau.
• Cov tshuaj tuaj yeem muab qee qhov nqus mus rau hauv cov ntshav, thiab tom qab ntawd qhia nws qhov kev ua kom kho.
• Yog tias tom qab siv cov tshuaj rau ib lub sijhawm ntev ntev uas kho cov nyhuv tsis pom, nws yog qhov yuav tsum tau txiav nws txoj kev siv, sab laj tus kws tshaj lij.

Cia peb xav txog ntxiv qhov muaj pes tsawg leeg gentamicin ointment.

Cov tshuaj pleev Gentamicin los ntawm Actavis (duab)

Lub raj xa dej muaj 25 mg gentamicin sulfate. Cov tshuaj no yog cov tshuaj nquag ntawm cov tshuaj no.

Ntawm cov tshuaj pab tam sim no:

• paraffin nyuaj (52 - 54),
• kua paraffin
• cov roj dawb dawb.

Tom ntej no, koj yuav pom tias cov tshuaj pleev pleev gentamicin muaj ntau npaum li cas.

Dosage Cov Ntawv

Cov tshuaj muaj nyob rau hauv daim ntawv pleev tshuaj, npaj rau kev siv sab nraud. Sab hauv lub raj muaj 15 lossis 25 mg. tshuaj ntsuab tshuaj. Tus nqi ntawm gentamicin tshuaj pleev nyob rau hauv Russia pib los ntawm 57 rubles, nws nyob ntawm ntau npaum li cas ntawm cov tshuaj.

Tsis tas li ntawd, "Gentamicin" yog tsim cov hmoov, tov rau kev txhaj tshuaj.

Kev cuam tshuam nrog lwm yam tshuaj

Kev siv tib lub sij hawm gentamicin nrog cov tshuaj tua kab mob uas ua rau pom oto-, cov nyhuv nephrotic yog contraindicated:

Kev siv tib lub sij hawm ntawm gentamicin nrog Furosemide kuj yog contraindicated.

Siv cov tshuaj pleev "Gentamicin" nws pom zoo kom tsis txhob noj cov tshuaj uas muaj K +, Mg ++, Na +, Ca ++ ions, anions (nitrates, phosphates, sulfates).

Kev tsis sib haum ntawm gentamicin nrog rau cov tshuaj hauv qab no tau sau tseg: heparin, tshuaj uas pom tias tsis ruaj khov ntawm acidic pH, zoo li nrog cov kev daws teeb meem uas muaj alkaline pH.

• Hais txog Gentamicin Ointment, cov neeg mob tawm hauv kev tawm tswv yim zoo, txhua tus nyiam nws txoj kev tua kab mob, ua haujlwm antimicrobial zoo.
• Nyob rau tib lub sijhawm, tus nqi ntawm cov tshuaj yog pheej yig.
• Ntawm tus nqi qis, zoo tseem nyob siab.

Nco ntsoov cov lus qhia hauv qab no:

• "Gentamicin sulfate."
• Tayzomed.
• "Streptomycin sulfate."
• "Tobrex 2x."
• Kanamycin.
• Isofra.

Daim vis dis aus no qhia txog kev siv gentamicin hauv kev kis mob ntawm pob ntseg hauv tus menyuam:

Cov tshuaj tua kab mob tau ntev ntev los ruaj rau hauv tib neeg lub neej. Tam sim no koj tuaj yeem nrhiav cov tshuaj antimicrobial, tshuaj tua kab mob antibacterial, bactericidal gel los sis cov ntaub so, thiab lwm yam. Tab sis koj yuav tsum siv txhua txoj kev ua tib zoo saib. Tshwj xeeb tshaj yog thaum nws los txog rau cov tshuaj. Cov ntawv xov xwm hnub no yuav qhia koj tias Gentamicin-Akos yog dab tsi. Rau dab tsi siv tshuaj pleev no, thiab nyob rau hauv rooj plaub twg nws yog qhov zoo dua uas tsis lees nws, koj yuav kawm tau ntxiv.

Kev cuam tshuam rau kev muaj peev xwm tsav tsheb thiab cov txheej txheem nyuaj

Txij li thaum ototoxic cov kev tsis zoo muaj peev xwm ua tau thaum kho nrog gentamicin ointment, yuav tsum ceev faj thaum tsav tsheb thiab ua cov haujlwm uas yuav tsum muaj kev mloog ntxiv.

Cev xeeb tub thiab lactation

Hauv thawj peb lub hlis thaum cev xeeb tub, 0.1% gentamicin ointment tsis pom zoo. Hauv kev txiav thib ob thiab thib peb, kev siv tshuaj pleev yog ua tau nyob rau hauv rooj plaub thaum kev cia siab rau cov poj niam muaj peev xwm dhau qhov kev pheej hmoo rau tus me nyuam hauv plab.

Hauv ib qho me me, gentamicin kis mus rau hauv niam cov kua mis. Vim tias tsis muaj qhov nqus ntawm cov tshuaj hauv txoj hnyuv, kev txhim kho cov kev mob tshwm sim thaum lub sijhawm pub niam mis tau muaj tsawg.

Siv rau thaum yau

Raws li cov lus qhia, tshuaj pleev rau Gentamicin 0.1% yog sib kis rau cov menyuam yaus hnub nyoog qis dua 3 xyoos.

Nrog lub raum tsis ua haujlwm

Cov neeg mob uas muaj lub raum tsis ua hauj lwm zoo yuav tsum tau txiav txim siab nrog ceev faj.

Siv rau lub sijhawm qub

Kev siv cov tshuaj pleev gentamicin hauv cov neeg laus yuav tsum ceeb toom thiab kev saib xyuas lub sijhawm ua haujlwm rau lub raum.

Vim tias cov neeg nqus qis qis qis, qhov sib cuam tshuam hauv chaw khomob yog qhov tseem ceeb ntawm gentamicin nrog lwm cov tshuaj tsis zoo li. Muaj peev xwm tshwm sim tau los ntawm kev siv tshuaj pleev gentamicin nrog rau qee yam tshuaj:

• anions (nitrates, phosphates, sulfates, thiab lwm yam), sodium, potassium, calcium, magnesium ions: txo qis hauv kev ua ntawm gentamicin,
• streptomycin, monomycin, florimycin, ristamycin thiab lwm yam tshuaj tua kab mob nrog cov nyhuv nephrotoxic thiab ototoxic, nrog rau cov furosemide: sib koom tes nrog gentamicin tsis pom zoo,
• dioxidine: nce ntxim ntawm gentamicin vim yog kev sib txuam synergistic,
• penicillins thiab cephalosporins: inactivation ntawm gentamicin,
• heparin, kev daws teeb meem nrog alkaline pH, tsis khov ntawm acidic pH tshuaj: tsis sib xws nrog gentamicin,
• corticosteroids: ua ke siv nrog gentamicin.

Cov tshuaj pleev Gentamicin 0.1% tshuaj tiv thaiv cov tshuaj yog Gentamicin thiab Gentamicin-AKOS.

Cov lus thiab cov xwm txheej ntawm kev cia

Khaws ntawm qhov kub thiab txias tsis tshaj 20 ° C. Khaws tsis ncav cuag ntawm cov menyuam yaus.

Txee lub neej yog 3 xyoos.

Cov Cai Siv Tshuaj So

Tso tawm los ntawm kev kho mob.

Kev tshuaj xyuas txog Gentamicin Ointment 0.1%

Hauv kev txheeb xyuas cov tshuaj pleev Gentamicin 0.1%, cov neeg siv pom tau tias cov tshuaj pab kho cov qhov txhab ntiav thiab kub hnyiab, ua haujlwm sai thiab muaj txiaj ntsig. Tsis tas li ntawd, tshuaj pleev kuj muaj tus nqi qis.

Tus nqi ntawm cov tshuaj pleev Gentamicin 0.1% hauv cov chaw muag tshuaj

Tus nqi kwv yees 0.1% Gentamicin tshuaj pleev yog kwv yees li 70 rubles rau ib lub raj ntawm 15 g.

Hauv tsab xov xwm no, koj tuaj yeem nyeem cov lus qhia rau kev siv tshuaj yaj yeeb GentamicinCov. Muab cov lus pom zoo los ntawm cov neeg tuaj saib rau ntawm thaj chaw - cov neeg tau txais kev pab ntawm cov tshuaj no, nrog rau kev xav ntawm cov kws paub txog kev kho mob txog kev siv cov tshuaj tua kab mob Gentamicin hauv lawv cov kev coj ua. Qhov kev thov loj yog nquag ntxiv kev tshuaj xyuas koj ntawm cov tshuaj: cov tshuaj tau pab lossis tsis pab ua kom tshem tawm ntawm tus kabmob, muaj dab tsi tshwm sim thiab cov kev mob tshwm sim, tejzaum nws tsis tshaj tawm los ntawm tus tsim khoom hauv cov lus piav qhia. Gentamicin analogues nyob rau hauv muaj cov qauv txheej txheem qauv. Siv rau kev kho mob kis mob rau cov neeg laus, menyuam yaus, nrog rau lub sijhawm cev xeeb tub thiab lactation.

Gentamicin - Ib qho tshuaj tua kab mob ntau ntawm cov tshuaj aminoglycoside. Nws muaj cov nyhuv bactericidal. Nkag mus rau hauv cov kab mob ntawm cov cell ua kom zoo, inhibits cov synthesis ntawm cov protein pathogen.

Ua tau zoo tiv thaiv cov kab mob aerobic gram-tsis zoo: Escherichia coli, Shigella spp., Salmonella spp., Enterobacter spp., Klebsiella spp., Serratia spp., Proteus spp., Pseudomonas aeruginosa, Acinetobacter spp.

Kuj tseem nquag tawm tsam aerobic gram-zoo cocci: Staphylococcus spp. (suav nrog kev tawm tsam ntawm penicillins thiab lwm yam tshuaj tua kab mob), qee cov kab mob ntawm Streptococcus spp.

Neisseria meningitidis, Treponema pallidum, qee yam ntawm Kab mob Streptococcus spp., Cov kab mob Anaerobic tiv taus gentamicin.

Dexamethasone yog hluavtaws glucocorticosteroid (GCS), kev tiv thaiv kev tiv thaiv thiab kev ua xua uas yog 25 npaug ntau dua qhov kev txiav txim ntawm cortisol, uas yog GCS endogenous. Kev nkag mus ntawm dexamethasone los ntawm lub pob zeb nrog rau qhov tseem ceeb epithelium mus rau hauv lub ya raws ntawm chav sab nraud ntawm lub qhov muag yog qhov ua tau, txawm li cas los xij, nyob rau hauv tus txheej txheem mob los yog kev puas tsuaj rau epithelium, tus nqi nkag ntawm dexamethasone los ntawm lub qhov muag tseem ceeb nce.

Muaj pes tsawg leeg

Gentamicin (hauv daim ntawv ntawm sulfate) + kev tshem tawm.

Dexamethasone sodium phosphate + Gentamicin sulfate + kev tshem tawm (Dex tee thiab qhov muag pleev).

Cov Tshuaj Pharmacokinetics

Tom qab kev tswj hwm intramuscular, nws tau ceev ceev los ntawm qhov chaw txhaj tshuaj. Plasma protein khi yog tsawg (0-10%). Nws tau faib tawm hauv cov kua dej ntxiv hauv txhua lub cev nqaij. Cais tau los ntawm qhov tsis muaj teeb meem. Tsis yog metabolized. 70-95% yog tawm hauv cov zis, ib qho me me nrog bile.

Cov Khoom Qhia

• kis mob thiab kis mob los ntawm cov kab mob me me nkag siab rau gentamicin,
• rau kev siv tshuaj kho mob: mob cholecystitis, cholangitis, pyelonephritis, cystitis, mob ntsws, mob ntsws pleural empyema, peritonitis, sepsis, ventriculitis, purulent kab mob ntawm daim tawv nqaij thiab cov nqaij mos, ua mob viav vias, hlawv kab mob, kis kab mob ntawm cov pob txha thiab pob qij txha,
• siv rau sab nraud: pyoderma (incl.mob pob txha), mob ua paug rau cov leeg ntshav, mob txhab, mob sycosis, paronychia, mob ua paug rau cov tawv nqaij, mob ua paug, mob ua paug rau cov tawv nqaij, kis mob rau daim tawv nqaij ntawm ntau tus kab mob (kub hnyiab, qhov txhab, tsis yooj yim los kho qhov mob, kab tom). ,
• rau kev siv hauv zos: blepharitis, blepharoconjunctivitis, dacryocystitis, conjunctivitis, keratitis, keratoconjunctivitis, meibomite.

Tso Tawm Cov Ntawv

Cov tshuaj pleev Gentamicin 0.1%

Qhov muag poob qis 0.3% (Dex).

Kev daws rau kev ua haujlwm ntawm kev tso ntshav thiab tshuaj intramuscular (hno hauv ampoules rau kev txhaj tshuaj).

Lwm hom, txawm tias nws yog ntsiav tshuaj lossis qab zib, tsis muaj nyob.

Cov lus qhia rau kev siv thiab ntau npaum li cas

Teeb tus kheej, coj mus rau hauv tus account qhov hnyav thiab thaj tsam ze ntawm tus kab mob, qhov rhiab ntawm cov kab mob.

Nrog kev tso ntshav lossis tshuaj intramuscular rau cov laus, ib koob tshuaj yog 1-1.7 mg / kg, koob tshuaj txhua hnub 3-5 mg / kg, ntau zaus ntawm 2-4 zaug hauv ib hnub. Lub chav kawm ntawm kev kho mob yog 7-10 hnub. Raws li cov lus etiology ntawm tus kab mob, nws yog ib qho ua tau los siv koob tshuaj ntawm 120-160 mg ib hnub ib zaug rau 7-10 hnub lossis 240-280 mg ib zaug. IV Txoj kev lis ntshav yog nqa tawm rau 1-2 teev.

Rau cov menyuam yaus hnub nyoog ntau dua 2 xyoos, koob tshuaj gentamicin txhua hnub yog 3-5 mg / kg, qhov ntau zaus ntawm kev tswj hwm yog 3 zaug hauv ib hnub. Cov menyuam yug ua ntej thiab cov menyuam yug tshiab tau muab rau noj 2-5 mg / kg ib hnub twg, kev noj tshuaj ntau npaum li 2 zaug hauv ib hnub, cov menyuam hnub nyoog qis dua 2 xyoos raug samfwm kom noj ib zaug ntawm cov thawj coj 3 zaug hauv ib hnub.

Cov neeg mob uas ua tsis taus lub raum rov ua hauj lwm tas li yuav tsum tau kho cov koob tshuaj ntau npaum li cas nyob ntawm QC cov nqi.

Thaum ua ntawv thov saum toj siab, gentamicin yog instilled 1-2 tee hauv qis qis hauv hnab ua ke ntawm lub qhov muag cuam tshuam txhua 1-4 teev.

Rau kev siv sab nraud, thov siv 3-4 zaug hauv ib hnub.

Qhov siab noj ntau tshaj plaws txhua hnub: rau cov neeg laus thiab cov menyuam yaus nrog iv lossis tshuaj intramuscular - 5 mg / kg.

Sab sij huam

• xeev siab, ntuav,
• anemia, leukopenia, granulocytopenia, thrombocytopenia,
• oliguria
• proteinuria
• tsom kwm,
• lub raum tsis ua hauj lwm
• mob taub hau
• tsaug zog
• hnov lus
• tsis paub kev lag ntseg
• daim tawv nqaij ua pob
• khaus
• urticaria
• npaws
• Quincke's edema.

Cov Yuav Tsum Tau Ua

• muaj tshuaj tiv thaiv rau gentamicin thiab lwm yam tshuaj tua kab mob ntawm pawg aminoglycoside,
• hnov ntawm lub paj hlwb neuritis,
• mob raum tsis zoo,
• uremia
• cev xeeb tub
• lactation (noj niam mis).

Cev xeeb tub thiab lactation

Gentamicin yog sib kis thaum cev xeeb tub. Yog tias tsim nyog, siv thaum lactation yuav tsum tsis txhob pub mis niam.

Siv rau menyuam yaus

Kev thov yuav siv tau raws li kev haus tshuaj noj.

Cov lus qhia tshwj xeeb

Gentamicin tau siv nrog ceev faj hauv parkinsonism, myasthenia gravis, thiab ua rau lub raum tsis ua haujlwm. Thaum siv gentamicin, cov haujlwm ntawm lub raum, tshuaj xyuas thiab cov khoom siv vestibular yuav tsum tau saib xyuas.

Nrog rau kev siv sab nraud ntawm gentamicin ntev ntev rau ntawm thaj chaw loj ntawm daim tawv nqaij, nws yog qhov yuav tsum tau coj mus rau hauv tus account qhov ua tau rau qhov kev tshem tawm, tshwj xeeb tshaj yog rau cov neeg mob uas mob raum tsis ua haujlwm.

Yeeb tshuaj sib cuam tshuam

Nrog rau kev siv tib lub sijhawm nrog aminoglycosides, vancomycin, cephalosporins, ethacrylic acid, nce ntxiv ntawm oto- thiab cov teebmeem nephrotoxic yog qhov ua tau.

Nrog rau kev siv ua ke nrog indomethacin, muaj ib qho txo ​​qis hauv kev txiav tawm ntawm gentamicin, kev nce ntxiv hauv nws cov concentration hauv cov ntshav ntshav, thaum qhov kev pheej hmoo ntawm kev tsim cov tshuaj lom tsis muaj zog.

Nrog rau kev siv tib lub sijhawm nrog cov nyiaj rau inhalation anesthesia, opioid analgesics, txoj kev pheej hmoo ntawm kev tsim neuromuscular blockade nce, mus txog rau kev txhim kho apnea.

Nrog rau kev siv gentamicin thiab "voj" diuretics (furosemide, ethacrylic acid), cov tshuaj lom nyob rau hauv cov ntshav ntawm gentamicin ntau ntxiv, thiab yog li qhov kev pheej hmoo ntawm kev tsim cov tshuaj lom cov tshuaj tiv thaiv muaj ntau ntxiv.

Analogs ntawm cov tshuaj Gentamicin

Cov qauv ntawm cov qauv ua haujlwm:

• Garamycin,
• Gentamicin Akos,
• Gentamicin K,
• Gentamicin Ferein,
• Gentamicin sulfate,
• Gentamicin sulfate txhaj 4%,
• Cov tshuaj pleev Gentamicin.

Thaum tsis muaj cov tshuaj analogues ntawm cov tshuaj rau cov tshuaj yeeb dej caw, koj tuaj yeem ua raws cov txuas hauv qab no rau cov kab mob uas pab cuam rau cov tshuaj sib txuas thiab pom cov tshuaj muaj analogues rau kev kho mob nyhuv.

Hauv kev sib txuas nrog qhov tshwm sim ntau dua ntawm cov kab mob ntawm daim tawv nqaij, kev xaiv cov tshuaj muaj ntau zuj zus tuaj, cov nyhuv ntawm kev tsom mus rau kev sib txuas ntawm ntau cov kab mob me. Ntawm cov tshuaj zoo heev, ib hom tshuaj xws li Gentamicin Ointment tau tshwm sim.

Cov tshuaj no tau txais txiaj ntsig hauv ntau tus neeg mob vim tias nws tus nqi kho mob loj, ua kom muaj zog. Peb yuav xav txog cov lus qhia niaj hnub no rau kev siv tshuaj pleev gentamicin rau menyuam yaus thiab cov neeg laus, nws cov analogues, cov nqi thiab tshuaj xyuas txog nws.

Pharmacological kev txiav txim

Cov tshuaj hauv cov lus nug feem ntau muaj nyob hauv pawg aminoglycosides, cov neeg sawv cev ophthalmic. Gentamicin paub tias yog ib tus kab mob ua rau pom dav dav-ntau.

Cov Tshuaj Hauv Tshuaj

Gentamicin nquag tawm tsam ntau yam kab mob me. Nws ua rau ntau hom kev tawm tsam, nrog rau cov kab mob hauv qab no:

• Serratia spp.,.
• Pseudomonas aeruginosa,
• Salmonella spp.,
• Escherichia coli,
• Shigella spp.,.
• Dab Tsi Staphylococcus spp.,
• Proteus spp.

"Cov tshuaj pleev Gentamicin" tsis cuam tshuam rau cov kab mob anaerobic, hu ua fungi, viruses. Cov tshuaj no muaj cov kab mob bactericidal. Nws nkag mus rau cov xias ntawm cov kab mob me. Tom qab ntawd, tom qab kev khi ntawm gentamicin nrog 30S subunits ntawm ribosomes, protein synthesis yog inhibited hauv pathogenic microorganisms.

Cov Tshuaj Pharmacokinetics

• Cov tshuaj hauv nqe lus nug nkag mus los ntawm daim tawv nqaij tsis muaj zog. Thaum ua ntawv thov rau thaj chaw ntawm thaj tsam epidermis, tsuas yog 0.1% ntawm cov tshuaj yog nqus tau.
• Yog tias cov tshuaj no tau siv rau thaj tsam raug mob ntawm epidermis, nws yuav nqus tau yooj yim dua. Nrog rau kev puas tsuaj, hlawv thaj chaw ntawm daim tawv nqaij (1 cm2), kev nqus ntawm cov tshuaj nce ntxiv (nce mus txog 1.5 μg).
• Tom qab ib daim ntawv thov ntawm cov tshuaj mus rau epidermis, nws cov nyhuv raug sau tseg rau 8 txog 12 teev. Gentamicin ua rau mob tawm lub raum los ntawm lub cev. Nws tawm dhau los tsis hloov pauv vim kev pom kev glomerular.

Nyeem txog yuav ua li cas gentamicin tshuaj pleev siv nyob rau hauv kev kho mob poj niam, rau kev kho qhov muag, pob txuv thiab dab tsi tshuaj xyuas nws tau txais hauv cov neeg mob, nyeem rau.

Cov lus qhia rau kev siv tshuaj pleev gentamicin

Cov tshuaj yog sau tseg los tawm tsam kev kis mob thiab kis mob, tshwm sim ntawm qhov uas tau tshwm sim los ntawm cov kab mob me me rau lub cev gentamicin. Cov tshuaj yog siv los kho:

• thawj cov mob ntawm tus mob epidermis (furunculosis, mob voos, mob pob qij txha, ua paug rau hauv lub cev),
• kev kis mob thib ob ntawm cov kab mob epidermis (kab mob sib kis mob, mob dermatitis, ua paug rau cov leeg ntshav, muaj cov kab mob kis, ua mob rau daim tawv nqaij, ua rau mob ua paug, ua rau mob ua paug, ua mob ua pob ua si rau lub cev).
• ntxiv rau hauv kev kho rau kev kho mob rau cov mob txhab uas muaj tus kab mob sib kis, mob ua paug rau daim tawv nqaij, mob ua paug me, kub hnyiab ntawm daim tawv nqaij nrog tus mob kis (qib 3, 3A), txiav, tawv nqaij tom qab kev kuaj mob.

Gentamicin yog rau cov kev siv:

Gentamecin kuj tseem siv nyob rau hauv muaj qhov muag ntawm optic neuritis, cov kev kho mob nyuaj ntawm otitis media hauv cov neeg laus, suav nrog otitis externa, ua ib qho kev pab nyob rau hauv muaj prostate adenoma rau cov txiv neej.

Cov lus qhia phau ntawv

Qhov ntau npaum li cas rau txhua tus neeg mob yog xam ib qho zuj zus los ntawm nws tus kws kho mob. Yuav kom suav qhov ntau npaum li cas, tus kws kho mob yuav siv mus rau hauv tus txheej txheem thaj tsam ntawm qhov chaw txhab, mob hnyav ntawm tus kab mob, qhov ntsuas ntawm rhiab ntawm lub pathogen.

• Rau kev siv sab nraud ntawm cov tshuaj, nws raug nquahu kom ua 3 rau 4 kev kho mob ib hnub. Siv tshuaj pleev "Gentamicin" rau thaj tsam teeb meem ntawm daim tawv nqaij muaj txheej nyias nyias. Yog tias kua paug, cov nqaij hlav necrotic muaj nyob rau thaj tsam cuam tshuam ntawm thaj tsam epidermis, lawv yuav tsum tau muab tshem tawm, tom qab ntawd pleev yuav tsum tau siv. Yog tias qhov kev puas tsuaj rau ntawm tus mob epidermis yog qhov tseem ceeb, nws raug nquahu kom siv tshuaj txhua hnub nyob hauv thaj tsam 200 g ntawm tshuaj pleev.
• Hauv kev kho mob ntawm qhov muag puas tsuaj, cov tshuaj yeeb yaj kiab yog siv nyob rau hauv daim ntawv ntawm dauv. Koj xav tau 1 - 2 ncos, uas muaj nyob rau hauv hnab looj tes ua ke (qis dua).
• Yog tias cov tshuaj raug muab rau tshuaj intramuscularly, tom qab ntawd ib koob tshuaj yog 1 txog 1.7 mg / kg. Hauv qhov no, qhov seem txhua hnub yog 3 txog 5 mg / kg.

Gentamicin yog contraindicated thaum cev xeeb tub. Qhov no yog vim muaj qhov tshwj xeeb tias cov tshuaj muaj peev xwm nkag mus rau hauv hematoplacental barrier, yog li ncav cuag tus me nyuam hauv nws tus kheej, nws cov ntaub so ntswg. Raws li kev tshawb nrhiav los ntawm cov kws tshawb fawb tsiaj, gentamicin nthuav qhia kev muaj tshuaj lom tsiaj txhu.

Nws yog txwv tsis pub siv cov tshuaj pleev "Gentamicin" hauv thawj peb lub hlis thaum cev xeeb tub. Yog hais tias lub hom phiaj tau txais txiaj ntsig rau leej niam ho muaj ntau tshaj qhov muaj feem yuav ua rau tus me nyuam hauv plab, cov tshuaj tau tso cai siv hauv II, III trimesters.

Yog tias tus poj niam tabtom pub mis niam, nws yuav tsum tsum tsis pub mis niam thaum kho. Qhov kev ceeb toom no yog qhov tsim nyog vim tias gentamicin kis mus rau hauv niam cov kua mis. Thaum tsis muaj kev nqus ntawm cov tshuaj los ntawm cov hnyuv zom, cov kev mob tshwm sim tsis tshwm sim.

Gentamicin tseem tuaj yeem siv rau kev mob prostatitis, raws li cov yeeb yaj kiab no hais txog:

Cov Yuav Tsum Tau Ua

Ntawm cov contraindications, peb nco ntsoov cov hauv qab no:

1. Lub xub ntiag ntawm kev tiv thaiv tsis haum hauv tus neeg mob mus rau cov khoom tseem ceeb, uas yog gentamicin.
2. Lub xub ntiag ntawm nce raug rhiab rau cov ntu ntu.
3. Lub xub ntiag tsis ua haujlwm.
4. Lub hnub nyoog qis dua 3 xyoos.
5. Kev qhia ntawm aminoglycosides.
6. Nrog neuritis ntawm auditory cov hlab ntsha, nws yog qhov yuav tsum siv cov tshuaj nrog kev ceev faj los kho thaj chaw loj ntawm cov kabmob epidermis.

Sab sij huam

Kev siv cov tshuaj hauv cov lus nug tuaj yeem ua rau cov kev mob tshwm sim hauv qab no:

1. Hauv qhov system hematopoietic: granulocytopenia, ua haujlwm ntshav, leukopenia, thrombocytopenia.
2. Hauv lub plab zom mov: hyperbilirubinemia, ntuav, xeev siab, nce transaminase kev ua haujlwm hauv lub siab.
3. Hauv cov hlab zis: microhematuria, proteinuria, lub raum tsis ua haujlwm, oliguria.
4. Hauv cov hlab ntsha hlwb (CNS, peripheral NS): qaug zog, tsis tuaj yeem tsis hnov ​​lus, mob taub hau, cuam tshuam ntawm kev ua haujlwm ntawm lub tshuab vestibular, pob ntseg tsis hnov, ua kom cov leeg tsis ua haujlwm.

Ntxiv rau cov kev mob tshwm sim saum toj no, cov neeg mob kuj tuaj yeem ua xua nyob rau hauv daim ntawv ntawm daim tawv nqaij ua pob khaus, khaus, urticaria, tsis tshua muaj tshwm sim hauv Quincke's edema. Tsis tas li, thaum noj gentamicin, paroxysmal qhov chaw kiv taub hau yuav tshwm sim.

Cov lus qhia tshwj xeeb

• Cov tshuaj yuav tsum tau siv kom zoo zoo nyob rau hauv muaj cov kab mob xws li myasthenia gravis, parkinsonism, lub raum tsis ua haujlwm.
• Siv "Gentamicin tshuaj pleev" rau kev siv tshuaj ntsuab rau thaj chaw muaj ntau ntawm epithelium, tsis txhob hnov ​​qab txog cov nyhuv resorptive ntawm cov tshuaj. Hauv tshwj xeeb, qhov no siv rau cov uas muaj kev mob raum (mob raum).
• Kev siv hauv zos tuaj yeem pab txhawb qhov kev nce siab ntawm ntau cov kab mob. Thaum tsis muaj tshuaj kho kom pom kev ceeb toom, tus neeg mob yuav xav tau kev pab tswv yim tshwj xeeb.
• Qhov ntau zaus ntawm kev tawm tsam tsis haum nce mus txog 1.4%. Feem ntau ntawm cov neeg mob rhiab heev dua thaum siv tshuaj pleev rau lub sijhawm tseem ceeb. Cov kev mob tshwm sim ntau dua thiab pom meej dua tshwm sim tom qab kev kho mob nrog cov tshuaj ntawm thaj chaw loj ntawm epidermis.

Kev cuam tshuam nrog lwm yam tshuaj

Kev siv tib lub sij hawm gentamicin nrog cov tshuaj tua kab mob uas ua rau pom oto-, cov nyhuv nephrotic yog contraindicated:

Kev siv tib lub sij hawm ntawm gentamicin nrog Furosemide kuj yog contraindicated.

Siv cov tshuaj pleev "Gentamicin" nws pom zoo kom tsis txhob noj cov tshuaj uas muaj K +, Mg ++, Na +, Ca ++ ions, anions (nitrates, phosphates, sulfates).

Kev tsis sib haum ntawm gentamicin nrog rau cov tshuaj hauv qab no tau sau tseg: heparin, tshuaj uas pom tias tsis ruaj khov ntawm acidic pH, zoo li nrog cov kev daws teeb meem uas muaj alkaline pH.

• Hais txog Gentamicin Ointment, cov neeg mob tawm hauv kev tawm tswv yim zoo, txhua tus nyiam nws txoj kev tua kab mob, ua haujlwm antimicrobial zoo.
• Nyob rau tib lub sijhawm, tus nqi ntawm cov tshuaj yog pheej yig.
• Ntawm tus nqi qis, zoo tseem nyob siab.

Nco ntsoov cov lus qhia hauv qab no:

• "Gentamicin sulfate."
• Tayzomed.
• "Streptomycin sulfate."
• "Tobrex 2x."
• Kanamycin.
• Isofra.

Daim vis dis aus no qhia txog kev siv gentamicin hauv kev kis mob ntawm pob ntseg hauv tus menyuam:

Cov tshuaj tua kab mob tau ntev ntev los ruaj rau hauv tib neeg lub neej. Tam sim no koj tuaj yeem nrhiav cov tshuaj antimicrobial, tshuaj tua kab mob antibacterial, bactericidal gel los sis cov ntaub so, thiab lwm yam. Tab sis koj yuav tsum siv txhua txoj kev ua tib zoo saib. Tshwj xeeb tshaj yog thaum nws los txog rau cov tshuaj. Cov ntawv xov xwm hnub no yuav qhia koj tias Gentamicin-Akos yog dab tsi. Rau dab tsi siv tshuaj pleev no, thiab nyob rau hauv rooj plaub twg nws yog qhov zoo dua uas tsis lees nws, koj yuav kawm tau ntxiv.

Cov chaw muag tshuaj ntawm cov tshuaj: yuav ua li cas cov tshuaj ua haujlwm, nws tsis tuaj yeem ua dab tsi?

Ua ntej koj kawm txog cov tshuaj tua kab mob hu ua "Gentamicin-Akos" (rau cov tshuaj pleev no yog tshuaj), tsim nyog kom nws paub nws zoo dua. Cov tshuaj yog xim daj-pob tshab, uas suav nrog cov khoom ntawm tib lub npe. Qhov gentamicin tivthaiv yog hais txog cov tshuaj tua kabmob aminoglycoside.

Cov tshuaj yog muaj peev xwm ua kom muaj cov kab mob bactericidal thiab tshem tawm cov kab mob microbial. Cov tshuaj muaj qhov pom dav ntawm qhov kev txiav txim. Nws sai sai rau cov kab mob hauv daim nyias nyias phab ntsa, tiv thaiv nws kev sib tov. Cuam ntau cov kab mob gram-zoo, thiab ntxiv rau yuav luag txhua yam gram-tsis zoo. Txawm hais tias nws ua tau zoo, Gentamicin-Akos tsis muaj peev xwm tshem tawm tus mob meningococcal, treponema, thiab qee yam kab mob staphylococcus. Anaerobic cov kab mob me me kuj tiv taus cov tshuaj no.

Cov lus qhia rau kev siv hais li cas: kev ntsuas thiab contraindications

Yog tias koj npaj siab siv tshuaj pleev pleev cov tshuaj pleev Gentamicin-Akos, cov lus qhia rau kev siv yuav qhia koj txog qhov kev xav tau no. Cov lej nchav sau cov tshuaj pab nrog. Ntawm cov ntsuas:

• cov kab mob ntawm daim tawv nqaij
• kev ua neeg lom zem pyoderma,
• furunculosis thiab sab nraum folliculitis,
• paronychia, sycosis,
• seborrheic dermatitis (mob),
• pob txuv
• mob voos voos uas ua tawm los ntawm cov leeg ntshav.

Tsis txhob siv cov tshuaj pleev nrog kev ua kom lub siab tsis zoo rau cov tshuaj nquag, neuritis ntawm cov khoom hnov. Mob raum tsis zoo, mob rwj, lactation thiab cev xeeb tub tseem ua mob tsis muaj mob.

Eczematous dermatitis: kev siv tshuaj pleev tua kabmob

Feem ntau cov neeg uas hu rau kws kho qhov muag nrog xoom xoo ntawm pob khaus hnov ​​cov kev kuaj mob no. Eczematous dermatitis yog kev tsis haum tshuaj, tshwm sim los ntawm daim tawv nqaij liab, txau thiab tsim cov hlwv me me. Yog hais tias tus kab mob tsis tau pib, ces txoj kev kho feem ntau tsis tas yuav siv tshuaj tua kab mob. Antihistamines, kho tshuaj pleev yog kho rau tus neeg mob.

Tab sis nws tseem tshwm sim tias cov npuas ua rau pib tawg lossis qhib los ntawm tus neeg mob nws tus kheej. Hauv qhov no, kev sib kis theem nrab tau tshwm sim. Hauv cov xwm txheej no, cov tshuaj "Gentamicin-Akos" yog tsim nyog kho. Vim li cas cov tshuaj pleev siv rau hauv cov kis zoo li no? Cov tshuaj muaj peev xwm tshem tawm cov kab mob sib xyaw nrog. Qhov kev txiav txim no yuav ceev kho. Siv cov tshuaj no rau sab nraud, ob zaug ib hnub. Yog tias siv tshuaj pleev ntxiv, tom qab ntawd koj yuav tsum mus so nruab nrab ntawm lawv.

Yuav Gentamicin-Akos pab nrog tus mob hu ua paronychia?

Kev kho cov kab mob periungual inflamed infering feem ntau yog nrog tshuaj tua kab mob.Qhov ua kom muaj tus kab mob tuaj yeem yog qhov sib txawv: kev kis kab mob los yog pwm, kev xwm txheej, hluav taws xob, kev ua tsis tau zoo, thiab lwm yam. Yog tias suppuration pib, uas ua rau paronychia, kev kho mob yuav tsum tsim nyog los ntawm kev siv tshuaj tua kab mob.

"Gentamicin-Akos" yog thov rau thaj tsam inflamed nyob rau hauv daim ntawv ntawm cov compress. Kev npaj ua ntej tuaj yeem qhib qhov rooj. Tab sis nws yog tsis yooj yim sua kom ntawm nws tus kheej nqa tawm li kev ntxias. Txhawm rau kom tsis txhob ua rau koj tus kheej tsis zoo, koj yuav tsum sab laj tus kws phais neeg. Tom qab cov txheej txheem, thov siv cov tshuaj nrog ib txheej nyias ntawm cov tawv nqaij ntawm cov tawv nqaij, txais ib feem ntawm daim tawv nqaij noj qab haus huv. Tso cev khaub ncaws uas tsis tsw lwj thiab muab cev ntiv tes tso. Qhov kev tsim no tsis tuaj yeem ntub. Koj yuav tsum hloov daim ntaub qhwv 3-4 zaug ib hnub.

Kev txheeb xyuas ntawm uas nws yuav nthuav kom paub cov neeg siv khoom

Cov neeg mob feem ntau nug lawv tus kheej: vim li cas tus kws kho mob tau sau tshuaj rau Gentamicin-Akos, vim li cas? Cov tshuaj pleev, thaum nws tig mus, tuaj yeem tiv thaiv ntau yam kab mob ntawm cov tawv nqaij. Raws li kev txheeb xyuas, feem ntau cov neeg siv khoom siv tshuaj tau los tua cov rwj thiab txawm tias mob ntxau ntawm lawv lub ntsej muag. Yog hais tias qhov mob tshwm sim los ntawm cov kab mob meej, ces cov tshuaj yuav pab koj. Cov tswv yim zoo yog tsim txog nws. Txog qee leej neeg, tshuaj tiv thaiv kab mob tau pab kho tus kab mob rhinitis (nrog rau siv cov ntswg).

Tab sis, zoo ib yam li lwm yam kev kho mob, muaj tshuaj tua kab mob thiab tsis zoo tshuaj xyuas. Qee cov neeg siv khoom tsis txaus siab ntawm cov tshuaj. Lawv tau hais tias cov roj pleev tsis tau pab lawv daws qhov teebmeem nkaus xwb, tabsis tseem ntxiv tau ntau lwm yam kev mob tsis zoo tas mus li. Feem ntau peb tab tom tham txog kev ua xua. Qhov no yog ib qho ntawm cov kev mob tshwm sim ntawm cov tshuaj. Yog tias nws tshwm sim, koj yuav tsum tau sab laj ib tus kws kho mob kom pab tswv yim.

Hloov ib txoj kev xaus

Los ntawm tsab xov xwm koj tau kawm txog dab tsi Gentamicin-Akos tshuaj pleev pab kho mob. Cov tshuaj muaj txiaj ntsig zoo rau kev tua cov kab mob ntawm daim tawv nqaij, suppurations, hlawv roj. Cov cuab yeej tseem siv los kho cov kab mob ocular. Txawm hais tias muaj tus yam ntxwv zoo thiab tau txais txiaj ntsig zoo ntawm cov tshuaj, tsis txhob ua phem rau nws.

Tsis txhob siv cov tshuaj pleev pleev yam tsis muaj kws kho mob sau. Nco ntsoov tias qhov tsis txaus siab ntawm kev kho tsis raug. Yog hais tias tus mob yog tshwm sim los ntawm ib tus kab mob fungal los yog tus kab mob, ces cov tshuaj yuav tsis pab koj. Ntxiv mus, nws yuav tua cov kab mob hauv ntuj, tsim kom muaj kev tiv thaiv zoo tshaj plaws rau kev ua tiav cov kab mob. Kho tau kom raug!

Gentamicin tshuaj pleev 0.1% yog tshuaj tua kab mob nrog cov nyhuv bactericidal rau kev siv sab nraud.

Tso tawm daim ntawv thiab muaj pes tsawg leeg

Daim ntawv koob tshuaj - tshuaj pleev rau kev siv sab nrauv 0.1%: los ntawm daj mus rau xim dawb (hauv ib lub raj txhuas 15 g, hauv ib daim ntawv thawv 1 lub raj).

Txheej Txheem 1 g tshuaj pleev:

• cov tshuaj nquag yog gentamicin (nyob rau hauv daim ntawv ntawm gentamicin sulfate) - 0.001 g,
• kev nthuav dav: khoom roj av roj av paraffin, muag dawb paraffin.

Cov Tshuaj Hauv Tshuaj

Gentamicin, ib hom tshuaj tua kab mob ntau yam-nyob rau hauv pawg, aminoglycosides ntawm lub cim thib ob. Tsis zoo li cov tshuaj tua kab mob bacteriostatic, aminoglycosides ncaj qha ua rau kev tuag ntawm cov kab mob me me rhiab rau lawv, tsis hais txog theem ntawm lawv cov kev ua me nyuam. Cov kab mob bactericidal ntawm gentamicin yog nquag nkag mus ntawm cov kab mob los ntawm cov cell membrane, qhov tsis muaj kev cuam tshuam ntawm cov kab mob ribosomes mus rau 30S subunits, thiab kev tsim ntawm ib txoj hauv kev thauj ribonucleic acid (tRNA) thiab matrix ribonucleic acid (mRNA). Yog li, gentamicin cuam tshuam cov kev thaiv txoj haujlwm ntawm cytoplasmic membranes ntawm microorganisms thiab inhibits cov synthesis ntawm pathogen protein.

Gentamicin sulfate nquag tiv thaiv cov kab mob aerobic gram-tsis zoo xws li: salmonella spp., Shigella spp., Escherichia coli, Serratia spp., Klebsiella spp., Enterobacter spp., Acinetobacter spp., Pseudomonas aeruginosa, Proteus spp. (indolegative thiab indolpositive).

Cov tshuaj tua kab mob tseem ua haujlwm los tiv thaiv cov kab mob aerobic gram-zoo xws li Staphylococcus spp. (suav nrog hom kab mob penicillin-thiab methicillin-tiv taus kab mob), qee cov kab mob ntawm Streptococcus spp.

Kev tawm tsam gentamicin yog qhia los ntawm Treponema pallidum, Neisseria meningitidis, kab mob anaerobic, qee cov kab mob ntawm Streptococcus spp.

Cov Tshuaj Pharmacokinetics

Rau kev siv sab nraud, gentamicin yog xyaum tsis tau nqus los ntawm daim tawv nqaij du nto. Thaum ua ntawv thov rau thaj chaw loj ntawm daim tawv nqaij, zoo li ua rau puas los yog npog nrog cov nqaij mos granulation, daim tawv nqaij tau nqus yooj yim thiab sai txaus. Kev nqus dej ntawm lub cev nrog 1 cm2 ntawm tshuaj pleev rau ntawm lub qhov txhab lossis qhov txhab tuaj yeem ncav cuag 1.5 μg ntawm gentamicin. Cov tshuaj tsis ua haujlwm tsis txawv txav los ntawm lub raum, feem ntau yog vim muaj cov glomerular pom.

Kev ntsuas rau siv

• thawj cov kab mob kis rau ntawm daim tawv nqaij thiab (lossis) cov nqaij mos ua rau muaj mob microflora: ua rau mob cov nqaij hauv lub cev, nqaij mos (nrog rau cov leeg tsis muaj zog), furunculosis, paronychia, sycosis, mob pob txuv,
• kev kis mob rau cov tawv nqaij thib ob: cov mob ua kom mob tawv nqaij (nrog rau seborrheic, tiv tauj thiab eczematous), cov kab mob kis tau rau lub cev muaj kab mob thiab kis ua mob rau daim tawv,
• muaj mob rau daim tawv nqaij ntawm ntau txoj kev ua haujlwm: mob (nrog rau sagging, phais), txiav, kub hnyiab (tsis yooj yim, II - IIIA degrees), mob kiav txhab (suav nrog varicose), kab tom,
• mob daim tawv nqaij ua qog thiab lub pob (tom qab qhib thiab hnoos tawm).

• concomitant systemic kev tswj hwm ntawm aminoglycosides,
• thawj peb hlis ntawm cev xeeb tub
• hnub nyoog txog li 3 xyoos
• ntxiv rau ib tus neeg rhiab rau gentamicin lossis lwm yam aminoglycosides.

• mob raum tsis ua hauj lwm
• lub hlis thib ob thiab zaum thib peb ntawm cev xeeb tub, lactation,
• hnub nyoog siab heev.

Gentamicin ointment 0.1% yuav tsum siv nrog kev ceev faj yog tias nws yuav tsum tau siv nws rau thaj chaw loj ntawm daim tawv nqaij hauv cov neeg mob uas hnov ​​mob neuritis, parkinsonism, myasthenia, botulism.

Cov lus qhia rau kev siv tshuaj pleev cov tshuaj pleev Gentamicin 0.1%: cov qauv thiab ntau npaum li cas

Gentamicin tshuaj pleev 0.1% yog siv rau sab nraud. Cov tshuaj siv rau hauv ib txheej txheej nyias mus rau thaj tsam ntawm daim tawv nqaij tom qab tshem tawm purulent thiab necrotic masses 2-3 zaug hauv ib hnub. Nrog cov qhov txhab txuas ntxiv ntawm daim tawv nqaij, qhov siab tshaj plaws txhua hnub koob tshuaj gentamicin yuav tsum tsis pub tshaj 200 mg, uas sib haum rau 200 g ntawm tshuaj pleev. Lub sijhawm tiv thaiv yog txiav txim los ntawm tus kws kho mob.

Thaum lub sijhawm siv cov tshuaj pleev Gentamicin 0.1%, cov kev qhia hauv zos ntawm qhov kev ua haujlwm tsis zoo (kub hnov, khaus, liab), muaj kev fab tshuaj (urticaria, tawv nqaij ua pob, khaus, ua npaws, eosinophilia, angioedema) yog ua tau. Yog tias kev ua xua tshwm sim, cov tshuaj raug muab tso tseg thiab kho txoj kev kho kom noj tshuaj yog raug kho.

Thaum thov cov tshuaj pleev gentamicin ntev ntev rau thaj chaw loj ntawm daim tawv nqaij, qhov tshwm sim tsis zoo muaj peev xwm ua tau, tshwj xeeb tshaj yog rau cov neeg mob uas mob raum tsis zoo.

Tom qab siv cov tshuaj hla thaj chaw loj ntawm lub qhov txhab lossis hlawv cov nplaim taws, tshwj xeeb tshaj yog siv sijhawm ntev, nephrotic, ototoxic, thiab vestibular cov teebmeem yuav tshwm sim.

Txij li cov tshuaj muaj cov tshuab nqus qis, nws txoj kev siv ntau dhau tsis zoo.

Thaum muaj kev siv ntev ntev ntawm Gentamicin Ointment 0.1% hauv kev txhawb nqa ntau ntxiv, nrog rau cov qhov txhab ntawm daim tawv nqaij ntau dua, nephrotic (suav nrog rau azotemia, proteinuria) thiab ototoxic (kiv taub hau, tsis tshua muaj, hnov ​​lus tsis zoo), muaj kev ua haujlwm ntawm hepatic transaminases, hyperbilirubinemia, hloov cov roj ntsha sib xyaw hauv cov ntshav nruab nrog cev.

Gentamicin tshuaj pleev 0.1% tsis yog siv rau daim ntawv thov rau cov leeg mos, nrog rau hauv qhov muag.

Nrog lub sijhawm ntev ntawm kev siv tshuaj pleev gentamicin, kev txhim kho ntawm kev ua tiav yog ua tau.

Thaum kho nrog cov tshuaj, Nws raug nquahu kom siv cov tshuaj tua kab mob, vim tias siv tshuaj pleev gentamicin tuaj yeem ua rau txoj kev loj hlob ntawm cov kab mob tiv thaiv kab mob rau cov tshuaj tua kab mob, suav nrog cov kab mob fungal. Hauv qhov no, xws li thaum mob tawv nqaij, rov qab ua xua, lossis rov kis tus kab mob dua, kev kho nrog tshuaj pleev gentamicin yuav tsum tsis ua ntxiv thiab kev kho tsim nyog yuav tsum tau nqa tawm.

Cov tshuaj tsis pom zoo rau siv nrog kev sib txig ib qho kev tswj hwm ntawm aminoglycoside tshuaj tua kab mob vim tias muaj kev pheej hmoo ntawm kev phiv tshuaj lom.

Yog tias tom qab 1 lub lis piam ntawm kev thov tshuaj pleev, kev kho mob tsis tuaj, nws yog qhov yuav tsum tau sab laj nrog cov kws tshaj lij.

Thaum muaj kev kho mob rau thaj chaw loj ntawm daim tawv nqaij, tshwj xeeb tshaj yog ncua sijhawm ntev, nrog rau yog tias nws yuav tsum tau thov rau ntawm cov tawv nqaij uas puas, kev ua kom lub cev muaj zog ntawm cov tshuaj tua kab mob muaj peev xwm nce ntxiv. Hauv cov xwm txheej no, tshwj xeeb tshaj yog nyob rau menyuam yaus, kev ceev faj yuav tsum ua kom tawm dag zog, vim tias qhov kev pheej hmoo ntawm cov kab mob thoob ntiaj teb muaj ntau ntxiv.

Thaum siv cov tshuaj nyob hauv thaj chaw mos, nws yog ib qho tsim nyog yuav tsum tau coj mus rau hauv tus account tias tshuaj pleev tuaj yeem ua rau txo qis ntawm lub zog ntawm cov hnab looj latex vim yog qhov muag dawb paraffin uas muaj nyob hauv nws, yog li txo cov txiaj ntsig.

Kev cuam tshuam rau kev muaj peev xwm tsav tsheb thiab cov txheej txheem nyuaj

Txij li thaum ototoxic cov kev tsis zoo muaj peev xwm ua tau thaum kho nrog gentamicin ointment, yuav tsum ceev faj thaum tsav tsheb thiab ua cov haujlwm uas yuav tsum muaj kev mloog ntxiv.

Cev xeeb tub thiab lactation

Hauv thawj peb lub hlis thaum cev xeeb tub, 0.1% gentamicin ointment tsis pom zoo. Hauv kev txiav thib ob thiab thib peb, kev siv tshuaj pleev yog ua tau nyob rau hauv rooj plaub thaum kev cia siab rau cov poj niam muaj peev xwm dhau qhov kev pheej hmoo rau tus me nyuam hauv plab.

Hauv ib qho me me, gentamicin kis mus rau hauv niam cov kua mis. Vim tias tsis muaj qhov nqus ntawm cov tshuaj hauv txoj hnyuv, kev txhim kho cov kev mob tshwm sim thaum lub sijhawm pub niam mis tau muaj tsawg.

Siv rau thaum yau

Raws li cov lus qhia, tshuaj pleev rau Gentamicin 0.1% yog sib kis rau cov menyuam yaus hnub nyoog qis dua 3 xyoos.

Nrog lub raum tsis ua haujlwm

Cov neeg mob uas muaj lub raum tsis ua hauj lwm zoo yuav tsum tau txiav txim siab nrog ceev faj.

Siv rau lub sijhawm qub

Kev siv cov tshuaj pleev gentamicin hauv cov neeg laus yuav tsum ceeb toom thiab kev saib xyuas lub sijhawm ua haujlwm rau lub raum.

Vim tias cov neeg nqus qis qis qis, qhov sib cuam tshuam hauv chaw khomob yog qhov tseem ceeb ntawm gentamicin nrog lwm cov tshuaj tsis zoo li. Muaj peev xwm tshwm sim tau los ntawm kev siv tshuaj pleev gentamicin nrog rau qee yam tshuaj:

• anions (nitrates, phosphates, sulfates, thiab lwm yam), sodium, potassium, calcium, magnesium ions: txo qis hauv kev ua ntawm gentamicin,
• streptomycin, monomycin, florimycin, ristamycin thiab lwm yam tshuaj tua kab mob nrog cov nyhuv nephrotoxic thiab ototoxic, nrog rau cov furosemide: sib koom tes nrog gentamicin tsis pom zoo,
• dioxidine: nce ntxim ntawm gentamicin vim yog kev sib txuam synergistic,
• penicillins thiab cephalosporins: inactivation ntawm gentamicin,
• heparin, kev daws teeb meem nrog alkaline pH, tsis khov ntawm acidic pH tshuaj: tsis sib xws nrog gentamicin,
• corticosteroids: ua ke siv nrog gentamicin.

Cov tshuaj pleev Gentamicin 0.1% tshuaj tiv thaiv cov tshuaj yog Gentamicin thiab Gentamicin-AKOS.

Cov lus thiab cov xwm txheej ntawm kev cia

Khaws ntawm qhov kub thiab txias tsis tshaj 20 ° C. Khaws tsis ncav cuag ntawm cov menyuam yaus.

Txee lub neej yog 3 xyoos.

Cov Cai Siv Tshuaj So

Tso tawm los ntawm kev kho mob.

Kev tshuaj xyuas txog Gentamicin Ointment 0.1%

Hauv kev txheeb xyuas cov tshuaj pleev Gentamicin 0.1%, cov neeg siv pom tau tias cov tshuaj pab kho cov qhov txhab ntiav thiab kub hnyiab, ua haujlwm sai thiab muaj txiaj ntsig. Tsis tas li ntawd, tshuaj pleev kuj muaj tus nqi qis.

Tus nqi ntawm cov tshuaj pleev Gentamicin 0.1% hauv cov chaw muag tshuaj

Tus nqi kwv yees 0.1% Gentamicin tshuaj pleev yog kwv yees li 70 rubles rau ib lub raj ntawm 15 g.

Hauv tsab xov xwm no, koj tuaj yeem nyeem cov lus qhia rau kev siv tshuaj yaj yeeb GentamicinCov. Muab cov lus pom zoo los ntawm cov neeg tuaj saib rau ntawm thaj chaw - cov neeg tau txais kev pab ntawm cov tshuaj no, nrog rau kev xav ntawm cov kws paub txog kev kho mob txog kev siv cov tshuaj tua kab mob Gentamicin hauv lawv cov kev coj ua. Qhov kev thov loj yog nquag ntxiv kev tshuaj xyuas koj ntawm cov tshuaj: cov tshuaj tau pab lossis tsis pab ua kom tshem tawm ntawm tus kabmob, muaj dab tsi tshwm sim thiab cov kev mob tshwm sim, tejzaum nws tsis tshaj tawm los ntawm tus tsim khoom hauv cov lus piav qhia. Gentamicin analogues nyob rau hauv muaj cov qauv txheej txheem qauv. Siv rau kev kho mob kis mob rau cov neeg laus, menyuam yaus, nrog rau lub sijhawm cev xeeb tub thiab lactation.

Gentamicin - Ib qho tshuaj tua kab mob ntau ntawm cov tshuaj aminoglycoside. Nws muaj cov nyhuv bactericidal. Nkag mus rau hauv cov kab mob ntawm cov cell ua kom zoo, inhibits cov synthesis ntawm cov protein pathogen.

Ua tau zoo tiv thaiv cov kab mob aerobic gram-tsis zoo: Escherichia coli, Shigella spp., Salmonella spp., Enterobacter spp., Klebsiella spp., Serratia spp., Proteus spp., Pseudomonas aeruginosa, Acinetobacter spp.

Kuj tseem nquag tawm tsam aerobic gram-zoo cocci: Staphylococcus spp. (suav nrog kev tawm tsam ntawm penicillins thiab lwm yam tshuaj tua kab mob), qee cov kab mob ntawm Streptococcus spp.

Neisseria meningitidis, Treponema pallidum, qee yam ntawm Kab mob Streptococcus spp., Cov kab mob Anaerobic tiv taus gentamicin.

Dexamethasone yog hluavtaws glucocorticosteroid (GCS), kev tiv thaiv kev tiv thaiv thiab kev ua xua uas yog 25 npaug ntau dua qhov kev txiav txim ntawm cortisol, uas yog GCS endogenous. Kev nkag mus ntawm dexamethasone los ntawm lub pob zeb nrog rau qhov tseem ceeb epithelium mus rau hauv lub ya raws ntawm chav sab nraud ntawm lub qhov muag yog qhov ua tau, txawm li cas los xij, nyob rau hauv tus txheej txheem mob los yog kev puas tsuaj rau epithelium, tus nqi nkag ntawm dexamethasone los ntawm lub qhov muag tseem ceeb nce.

Muaj pes tsawg leeg

Gentamicin (hauv daim ntawv ntawm sulfate) + kev tshem tawm.

Dexamethasone sodium phosphate + Gentamicin sulfate + kev tshem tawm (Dex tee thiab qhov muag pleev).

Cov Tshuaj Pharmacokinetics

Tom qab kev tswj hwm intramuscular, nws tau ceev ceev los ntawm qhov chaw txhaj tshuaj. Plasma protein khi yog tsawg (0-10%). Nws tau faib tawm hauv cov kua dej ntxiv hauv txhua lub cev nqaij. Cais tau los ntawm qhov tsis muaj teeb meem. Tsis yog metabolized. 70-95% yog tawm hauv cov zis, ib qho me me nrog bile.

Cov Khoom Qhia

• kis mob thiab kis mob los ntawm cov kab mob me me nkag siab rau gentamicin,
• rau kev siv tshuaj kho mob: mob cholecystitis, cholangitis, pyelonephritis, cystitis, mob ntsws, mob ntsws pleural empyema, peritonitis, sepsis, ventriculitis, purulent kab mob ntawm daim tawv nqaij thiab cov nqaij mos, ua mob viav vias, hlawv kab mob, kis kab mob ntawm cov pob txha thiab pob qij txha,
• rau kev siv sab nraud: pyoderma (suav nrog kev ua mob ua paug), ua rau cov leeg ntshav, mob txhab, mob sycosis, paronychia, mob nqaij hlav tawv nqaij, mob ntxau, kab mob kis kab mob thib ob nrog cov kab mob fungal thiab kis ntawm daim tawv nqaij, kis mob ntawm daim tawv nqaij ntawm ntau yam etiologies (kub hnyiab, mob, mob hnyav kho qhov mob txhab, kab tom), mob pob khaus,
• rau kev siv hauv zos: blepharitis, blepharoconjunctivitis, dacryocystitis, conjunctivitis, keratitis, keratoconjunctivitis, meibomite.

Tso Tawm Cov Ntawv

Cov tshuaj pleev Gentamicin 0.1%

Qhov muag poob qis 0.3% (Dex).

Kev daws rau kev ua haujlwm ntawm kev tso ntshav thiab tshuaj intramuscular (hno hauv ampoules rau kev txhaj tshuaj).

Lwm hom, txawm tias nws yog ntsiav tshuaj lossis qab zib, tsis muaj nyob.

Cov lus qhia rau kev siv thiab ntau npaum li cas

Teeb tus kheej, coj mus rau hauv tus account qhov hnyav thiab thaj tsam ze ntawm tus kab mob, qhov rhiab ntawm cov kab mob.

Nrog kev tso ntshav lossis tshuaj intramuscular rau cov laus, ib koob tshuaj yog 1-1.7 mg / kg, koob tshuaj txhua hnub 3-5 mg / kg, ntau zaus ntawm 2-4 zaug hauv ib hnub. Lub chav kawm ntawm kev kho mob yog 7-10 hnub. Raws li cov lus etiology ntawm tus kab mob, nws yog ib qho ua tau los siv koob tshuaj ntawm 120-160 mg ib hnub ib zaug rau 7-10 hnub lossis 240-280 mg ib zaug. IV Txoj kev lis ntshav yog nqa tawm rau 1-2 teev.

Rau cov menyuam yaus hnub nyoog ntau dua 2 xyoos, koob tshuaj gentamicin txhua hnub yog 3-5 mg / kg, qhov ntau zaus ntawm kev tswj hwm yog 3 zaug hauv ib hnub.Cov menyuam yug ua ntej thiab cov menyuam yug tshiab tau muab rau noj 2-5 mg / kg ib hnub twg, kev noj tshuaj ntau npaum li 2 zaug hauv ib hnub, cov menyuam hnub nyoog qis dua 2 xyoos raug samfwm kom noj ib zaug ntawm cov thawj coj 3 zaug hauv ib hnub.

Cov neeg mob uas ua tsis taus lub raum rov ua hauj lwm tas li yuav tsum tau kho cov koob tshuaj ntau npaum li cas nyob ntawm QC cov nqi.

Thaum ua ntawv thov saum toj siab, gentamicin yog instilled 1-2 tee hauv qis qis hauv hnab ua ke ntawm lub qhov muag cuam tshuam txhua 1-4 teev.

Rau kev siv sab nraud, thov siv 3-4 zaug hauv ib hnub.

Qhov siab noj ntau tshaj plaws txhua hnub: rau cov neeg laus thiab cov menyuam yaus nrog iv lossis tshuaj intramuscular - 5 mg / kg.

Sab sij huam

• xeev siab, ntuav,
• anemia, leukopenia, granulocytopenia, thrombocytopenia,
• oliguria
• proteinuria
• tsom kwm,
• lub raum tsis ua hauj lwm
• mob taub hau
• tsaug zog
• hnov lus
• tsis paub kev lag ntseg
• daim tawv nqaij ua pob
• khaus
• urticaria
• npaws
• Quincke's edema.

Cov Yuav Tsum Tau Ua

• muaj tshuaj tiv thaiv rau gentamicin thiab lwm yam tshuaj tua kab mob ntawm pawg aminoglycoside,
• hnov ntawm lub paj hlwb neuritis,
• mob raum tsis zoo,
• uremia
• cev xeeb tub
• lactation (noj niam mis).

Cev xeeb tub thiab lactation

Gentamicin yog sib kis thaum cev xeeb tub. Yog tias tsim nyog, siv thaum lactation yuav tsum tsis txhob pub mis niam.

Siv rau menyuam yaus

Kev thov yuav siv tau raws li kev haus tshuaj noj.

Cov lus qhia tshwj xeeb

Gentamicin tau siv nrog ceev faj hauv parkinsonism, myasthenia gravis, thiab ua rau lub raum tsis ua haujlwm. Thaum siv gentamicin, cov haujlwm ntawm lub raum, tshuaj xyuas thiab cov khoom siv vestibular yuav tsum tau saib xyuas.

Nrog rau kev siv sab nraud ntawm gentamicin ntev ntev rau ntawm thaj chaw loj ntawm daim tawv nqaij, nws yog qhov yuav tsum tau coj mus rau hauv tus account qhov ua tau rau qhov kev tshem tawm, tshwj xeeb tshaj yog rau cov neeg mob uas mob raum tsis ua haujlwm.

Yeeb tshuaj sib cuam tshuam

Nrog rau kev siv tib lub sijhawm nrog aminoglycosides, vancomycin, cephalosporins, ethacrylic acid, nce ntxiv ntawm oto- thiab cov teebmeem nephrotoxic yog qhov ua tau.

Nrog rau kev siv ua ke nrog indomethacin, muaj ib qho txo ​​qis hauv kev txiav tawm ntawm gentamicin, kev nce ntxiv hauv nws cov concentration hauv cov ntshav ntshav, thaum qhov kev pheej hmoo ntawm kev tsim cov tshuaj lom tsis muaj zog.

Nrog rau kev siv tib lub sijhawm nrog cov nyiaj rau inhalation anesthesia, opioid analgesics, txoj kev pheej hmoo ntawm kev tsim neuromuscular blockade nce, mus txog rau kev txhim kho apnea.

Nrog rau kev siv gentamicin thiab "voj" diuretics (furosemide, ethacrylic acid), cov tshuaj lom nyob rau hauv cov ntshav ntawm gentamicin ntau ntxiv, thiab yog li qhov kev pheej hmoo ntawm kev tsim cov tshuaj lom cov tshuaj tiv thaiv muaj ntau ntxiv.

Analogs ntawm cov tshuaj Gentamicin

Cov qauv ntawm cov qauv ua haujlwm:

• Garamycin,
• Gentamicin Akos,
• Gentamicin K,
• Gentamicin Ferein,
• Gentamicin sulfate,
• Gentamicin sulfate txhaj 4%,
• Cov tshuaj pleev Gentamicin.

Thaum tsis muaj cov tshuaj analogues ntawm cov tshuaj rau cov tshuaj yeeb dej caw, koj tuaj yeem ua raws cov txuas hauv qab no rau cov kab mob uas pab cuam rau cov tshuaj sib txuas thiab pom cov tshuaj muaj analogues rau kev kho mob nyhuv.

Hauv kev sib txuas nrog qhov tshwm sim ntau dua ntawm cov kab mob ntawm daim tawv nqaij, kev xaiv cov tshuaj muaj ntau zuj zus tuaj, cov nyhuv ntawm kev tsom mus rau kev sib txuas ntawm ntau cov kab mob me. Ntawm cov tshuaj zoo heev, ib hom tshuaj xws li Gentamicin Ointment tau tshwm sim.

Cov tshuaj no tau txais txiaj ntsig hauv ntau tus neeg mob vim tias nws tus nqi kho mob loj, ua kom muaj zog. Peb yuav xav txog cov lus qhia niaj hnub no rau kev siv tshuaj pleev gentamicin rau menyuam yaus thiab cov neeg laus, nws cov analogues, cov nqi thiab tshuaj xyuas txog nws.

Cov yam ntxwv ntawm cov tshuaj

• Cov tshuaj nyob rau hauv kev txiav txim siab nrog kev siv sijhawm ntev yuav ua rau kev txhim kho ntawm cov kabmob ntawm cov kab mob pathogenic rau nws.
• Yog tias cov neeg mob mob raum tsis zoo siv cov tshuaj los kho thaj chaw loj ntawm daim tawv nqaij, cov nyhuv resorptive ua tau.
• Cov tshuaj tuaj yeem muab qee qhov nqus mus rau hauv cov ntshav, thiab tom qab ntawd qhia nws qhov kev ua kom kho.
• Yog tias tom qab siv cov tshuaj rau ib lub sijhawm ntev ntev uas kho cov nyhuv tsis pom, nws yog qhov yuav tsum tau txiav nws txoj kev siv, sab laj tus kws tshaj lij.

Cia peb xav txog ntxiv qhov muaj pes tsawg leeg gentamicin ointment.

Cov tshuaj pleev Gentamicin los ntawm Actavis (duab)

Lub raj xa dej muaj 25 mg gentamicin sulfate. Cov tshuaj no yog cov tshuaj nquag ntawm cov tshuaj no.

Ntawm cov tshuaj pab tam sim no:

• paraffin nyuaj (52 - 54),
• kua paraffin
• cov roj dawb dawb.

Tom ntej no, koj yuav pom tias cov tshuaj pleev pleev gentamicin muaj ntau npaum li cas.

Dosage Cov Ntawv

Cov tshuaj muaj nyob rau hauv daim ntawv pleev tshuaj, npaj rau kev siv sab nraud. Sab hauv lub raj muaj 15 lossis 25 mg. tshuaj ntsuab tshuaj. Tus nqi ntawm gentamicin tshuaj pleev nyob rau hauv Russia pib los ntawm 57 rubles, nws nyob ntawm ntau npaum li cas ntawm cov tshuaj.

Tsis tas li ntawd, "Gentamicin" yog tsim cov hmoov, tov rau kev txhaj tshuaj.

Pharmacological kev txiav txim

Cov tshuaj hauv cov lus nug feem ntau muaj nyob hauv pawg aminoglycosides, cov neeg sawv cev ophthalmic. Gentamicin paub tias yog ib tus kab mob ua rau pom dav dav-ntau.

Cov Tshuaj Hauv Tshuaj

Gentamicin nquag tawm tsam ntau yam kab mob me. Nws ua rau ntau hom kev tawm tsam, nrog rau cov kab mob hauv qab no:

• Serratia spp.,.
• Pseudomonas aeruginosa,
• Salmonella spp.,
• Escherichia coli,
• Shigella spp.,.
• Dab Tsi Staphylococcus spp.,
• Proteus spp.

"Cov tshuaj pleev Gentamicin" tsis cuam tshuam rau cov kab mob anaerobic, hu ua fungi, viruses. Cov tshuaj no muaj cov kab mob bactericidal. Nws nkag mus rau cov xias ntawm cov kab mob me. Tom qab ntawd, tom qab kev khi ntawm gentamicin nrog 30S subunits ntawm ribosomes, protein synthesis yog inhibited hauv pathogenic microorganisms.

Cov Tshuaj Pharmacokinetics

• Cov tshuaj hauv nqe lus nug nkag mus los ntawm daim tawv nqaij tsis muaj zog. Thaum ua ntawv thov rau thaj chaw ntawm thaj tsam epidermis, tsuas yog 0.1% ntawm cov tshuaj yog nqus tau.
• Yog tias cov tshuaj no tau siv rau thaj tsam raug mob ntawm epidermis, nws yuav nqus tau yooj yim dua. Nrog rau kev puas tsuaj, hlawv thaj chaw ntawm daim tawv nqaij (1 cm2), kev nqus ntawm cov tshuaj nce ntxiv (nce mus txog 1.5 μg).
• Tom qab ib daim ntawv thov ntawm cov tshuaj mus rau epidermis, nws cov nyhuv raug sau tseg rau 8 txog 12 teev. Gentamicin ua rau mob tawm lub raum los ntawm lub cev. Nws tawm dhau los tsis hloov pauv vim kev pom kev glomerular.

Nyeem txog yuav ua li cas gentamicin tshuaj pleev siv nyob rau hauv kev kho mob poj niam, rau kev kho qhov muag, pob txuv thiab dab tsi tshuaj xyuas nws tau txais hauv cov neeg mob, nyeem rau.

Cov lus qhia rau kev siv tshuaj pleev gentamicin

Cov tshuaj yog sau tseg los tawm tsam kev kis mob thiab kis mob, tshwm sim ntawm qhov uas tau tshwm sim los ntawm cov kab mob me me rau lub cev gentamicin. Cov tshuaj yog siv los kho:

• thawj cov mob ntawm tus mob epidermis (furunculosis, mob voos, mob pob qij txha, ua paug rau hauv lub cev),
• kev kis mob thib ob ntawm cov kab mob epidermis (kab mob sib kis mob, mob dermatitis, ua paug rau cov leeg ntshav, muaj cov kab mob kis, ua mob rau daim tawv nqaij, ua rau mob ua paug, ua rau mob ua paug, ua mob ua pob ua si rau lub cev).
• ntxiv rau hauv kev kho rau kev kho mob rau cov mob txhab uas muaj tus kab mob sib kis, mob ua paug rau daim tawv nqaij, mob ua paug me, kub hnyiab ntawm daim tawv nqaij nrog tus mob kis (qib 3, 3A), txiav, tawv nqaij tom qab kev kuaj mob.

Gentamicin yog rau cov kev siv:

• Hauv zosCov. Nws pab hauv kev kho cov kabmob xws li: dacryocystitis, blepharitis, meibomite, conjunctivitis, blepharoconjunctivitis, keratoconjunctivitis, keratitis.
• Niam txivCov. Nws pab txhawb rau kev kho mob ntawm cholangitis, ventriculitis, mob cholecystitis, mob ntsws, mob txhab, sepsis, pleural empyema, kis mob ntawm pob txha / pob qij txha, txhaws kab mob sib kis los ntawm tus mob epidermis, pyelonephritis, peritonitis, purulent kab mob ntawm cov nqaij mos, hlawv mob.
• Sab nraum zoovCov. Nws pab nyob rau hauv kev sib ntaus cov tiv thaiv kev kis mob, ua pob txuv ua paug, kab mob kis kab mob theem ob, kab mob sycosis, furunculosis, pyoderma, mob rau daim tawv nqaij ua mob, mob rau daim tawv nqaij ntawm ntau yam kev sib kis (kab tom, hlawv, nyuaj kho cov mob txhab, mob).

Gentamecin kuj tseem siv nyob rau hauv muaj qhov muag ntawm optic neuritis, cov kev kho mob nyuaj ntawm otitis media hauv cov neeg laus, suav nrog otitis externa, ua ib qho kev pab nyob rau hauv muaj prostate adenoma rau cov txiv neej.

Cov lus qhia phau ntawv

Qhov ntau npaum li cas rau txhua tus neeg mob yog xam ib qho zuj zus los ntawm nws tus kws kho mob. Yuav kom suav qhov ntau npaum li cas, tus kws kho mob yuav siv mus rau hauv tus txheej txheem thaj tsam ntawm qhov chaw txhab, mob hnyav ntawm tus kab mob, qhov ntsuas ntawm rhiab ntawm lub pathogen.

• Rau kev siv sab nraud ntawm cov tshuaj, nws raug nquahu kom ua 3 rau 4 kev kho mob ib hnub. Siv tshuaj pleev "Gentamicin" rau thaj tsam teeb meem ntawm daim tawv nqaij muaj txheej nyias nyias. Yog tias kua paug, cov nqaij hlav necrotic muaj nyob rau thaj tsam cuam tshuam ntawm thaj tsam epidermis, lawv yuav tsum tau muab tshem tawm, tom qab ntawd pleev yuav tsum tau siv. Yog tias qhov kev puas tsuaj rau ntawm tus mob epidermis yog qhov tseem ceeb, nws raug nquahu kom siv tshuaj txhua hnub nyob hauv thaj tsam 200 g ntawm tshuaj pleev.
• Hauv kev kho mob ntawm qhov muag puas tsuaj, cov tshuaj yeeb yaj kiab yog siv nyob rau hauv daim ntawv ntawm dauv. Koj xav tau 1 - 2 ncos, uas muaj nyob rau hauv hnab looj tes ua ke (qis dua).
• Yog tias cov tshuaj raug muab rau tshuaj intramuscularly, tom qab ntawd ib koob tshuaj yog 1 txog 1.7 mg / kg. Hauv qhov no, qhov seem txhua hnub yog 3 txog 5 mg / kg.

Gentamicin yog contraindicated thaum cev xeeb tub. Qhov no yog vim muaj qhov tshwj xeeb tias cov tshuaj muaj peev xwm nkag mus rau hauv hematoplacental barrier, yog li ncav cuag tus me nyuam hauv nws tus kheej, nws cov ntaub so ntswg. Raws li kev tshawb nrhiav los ntawm cov kws tshawb fawb tsiaj, gentamicin nthuav qhia kev muaj tshuaj lom tsiaj txhu.

Yog tias tus poj niam tabtom pub mis niam, nws yuav tsum tsum tsis pub mis niam thaum kho. Qhov kev ceeb toom no yog qhov tsim nyog vim tias gentamicin kis mus rau hauv niam cov kua mis. Thaum tsis muaj kev nqus ntawm cov tshuaj los ntawm cov hnyuv zom, cov kev mob tshwm sim tsis tshwm sim.

Gentamicin tseem tuaj yeem siv rau kev mob prostatitis, raws li cov yeeb yaj kiab no hais txog:

Cov Yuav Tsum Tau Ua

Ntawm cov contraindications, peb nco ntsoov cov hauv qab no:

1. Lub xub ntiag ntawm kev tiv thaiv tsis haum hauv tus neeg mob mus rau cov khoom tseem ceeb, uas yog gentamicin.
2. Lub xub ntiag ntawm nce raug rhiab rau cov ntu ntu.
3. Lub xub ntiag tsis ua haujlwm.
4. Lub hnub nyoog qis dua 3 xyoos.
5. Kev qhia ntawm aminoglycosides.
6. Nrog neuritis ntawm auditory cov hlab ntsha, nws yog qhov yuav tsum siv cov tshuaj nrog kev ceev faj los kho thaj chaw loj ntawm cov kabmob epidermis.

Sab sij huam

Kev siv cov tshuaj hauv cov lus nug tuaj yeem ua rau cov kev mob tshwm sim hauv qab no:

1. Hauv qhov system hematopoietic: granulocytopenia, ua haujlwm ntshav, leukopenia, thrombocytopenia.
2. Hauv lub plab zom mov: hyperbilirubinemia, ntuav, xeev siab, nce transaminase kev ua haujlwm hauv lub siab.
3. Hauv cov hlab zis: microhematuria, proteinuria, lub raum tsis ua haujlwm, oliguria.
4. Hauv cov hlab ntsha hlwb (CNS, peripheral NS):qaug zog, tsis tuaj yeem tsis hnov ​​lus, mob taub hau, cuam tshuam ntawm kev ua haujlwm ntawm lub tshuab vestibular, pob ntseg tsis hnov, ua kom cov leeg tsis ua haujlwm.

Ntxiv rau cov kev mob tshwm sim saum toj no, cov neeg mob kuj tuaj yeem ua xua nyob rau hauv daim ntawv ntawm daim tawv nqaij ua pob khaus, khaus, urticaria, tsis tshua muaj tshwm sim hauv Quincke's edema. Tsis tas li, thaum noj gentamicin, paroxysmal qhov chaw kiv taub hau yuav tshwm sim.

Cov lus qhia tshwj xeeb

• Cov tshuaj yuav tsum tau siv kom zoo zoo nyob rau hauv muaj cov kab mob xws li myasthenia gravis, parkinsonism, lub raum tsis ua haujlwm.
• Siv "Gentamicin tshuaj pleev" rau kev siv tshuaj ntsuab rau thaj chaw muaj ntau ntawm epithelium, tsis txhob hnov ​​qab txog cov nyhuv resorptive ntawm cov tshuaj. Hauv tshwj xeeb, qhov no siv rau cov uas muaj kev mob raum (mob raum).
• Kev siv hauv zos tuaj yeem pab txhawb qhov kev nce siab ntawm ntau cov kab mob.Thaum tsis muaj tshuaj kho kom pom kev ceeb toom, tus neeg mob yuav xav tau kev pab tswv yim tshwj xeeb.
• Qhov ntau zaus ntawm kev tawm tsam tsis haum nce mus txog 1.4%. Feem ntau ntawm cov neeg mob rhiab heev dua thaum siv tshuaj pleev rau lub sijhawm tseem ceeb. Cov kev mob tshwm sim ntau dua thiab pom meej dua tshwm sim tom qab kev kho mob nrog cov tshuaj ntawm thaj chaw loj ntawm epidermis.

Kev cuam tshuam nrog lwm yam tshuaj

Kev siv tib lub sij hawm gentamicin nrog cov tshuaj tua kab mob uas ua rau pom oto-, cov nyhuv nephrotic yog contraindicated:

Kev siv tib lub sij hawm ntawm gentamicin nrog Furosemide kuj yog contraindicated.

Kev tsis sib haum ntawm gentamicin nrog rau cov tshuaj hauv qab no tau sau tseg: heparin, tshuaj uas pom tias tsis ruaj khov ntawm acidic pH, zoo li nrog cov kev daws teeb meem uas muaj alkaline pH.

• Hais txog Gentamicin Ointment, cov neeg mob tawm hauv kev tawm tswv yim zoo, txhua tus nyiam nws txoj kev tua kab mob, ua haujlwm antimicrobial zoo.
• Nyob rau tib lub sijhawm, tus nqi ntawm cov tshuaj yog pheej yig.
• Ntawm tus nqi qis, zoo tseem nyob siab.

Nco ntsoov cov lus qhia hauv qab no:

• "Gentamicin sulfate."
• Tayzomed.
• "Streptomycin sulfate."
• "Tobrex 2x."
• Kanamycin.
• Isofra.

Daim vis dis aus no qhia txog kev siv gentamicin hauv kev kis mob ntawm pob ntseg hauv tus menyuam:

cov tshuaj heev - gentamicin (nyob rau hauv daim ntawv ntawm gentamicin sulfate) - 25 mg,

tus zam - lub cev paraffin 52-54, kua paraffin, mos paraffin, dawb.

Pharmacological kev txiav txim

Gentamicin yog tus cwj pwm tau los ntawm kev pom tseeb hauv kev ua haujlwm ntawm antimicrobial. Nws nquag ua rau cov kab mob feem ntau gram-negative thiab gram-zoo: Pseudomonas aeruginosa, Escherichia coli, Proteus spp., Klebsiella spp., Serratia spp., Salmonella spp., Shigella spp., Staphylococcus spp. Cov tshuaj tsis cuam tshuam rau tus kab mob anaerobic, fungi, viruses. Nws muaj cov nyhuv bactericidal. Nquag nkag mus rau lub cell cell ntawm cov kab mob, khi rau 30S subunit ntawm cov kab mob ribosomes thiab inhibits cov synthesis ntawm pathogen protein.

Cev xeeb tub thiab lactation

Gentamicin hla cov nyom hematoplacental thaiv thiab mus txog cov ntaub so ntswg hauv plab. Cov kev tshawb fawb tsiaj tau pom tias muaj kev ua me nyuam toxicity ntawm gentamicin.

Gentamicin tshuaj pleev yuav tsum tsis txhob siv thawj lub hlis hauv plab thaum cev xeeb tub. Hauv II-III trimesters, kev siv tshuaj pleev gentamicin yog ua tau thaum muaj txiaj ntsig xav tau rau leej niam outweighs qhov kev pheej hmoo rau tus me nyuam hauv plab.

Gentamicin tawm hauv cov kua me nrog niam cov kua mis. Vim tias tsis muaj qhov nqus ntawm cov tshuaj los ntawm txoj hnyuv, qhov tshwm sim ntawm kev mob tshwm sim thaum pub niam mis yog tsis zoo li.

Tsuas tshuaj thiab tswj hwm

Gentamicin tshuaj pleev yog pleev rau sab nraud kom qhuav tawv nqaij.

Cov tshuaj no tau thov rau thaj tsam cuam tshuam ntawm daim tawv nqaij tom qab tshem tawm cov kua paug thiab necrotic loj, nrog ib txheej nyias 2-3 zaug ib hnub, nrog hlawv - 2-3 zaug hauv ib lub lis piam. Nrog rau kev raug mob hlawv ntau, qhov tshuaj txhua hnub ntawm tshuaj pleev yuav tsum tsis pub tshaj 200 g (200 mg ntawm cov tshuaj tua kab mob). Lub sijhawm kho yog nyob ntawm tus qauv thiab qhov mob hnyav thiab yog 7-14 hnub.

Hauv kev kho cov kab mob ua kom mob dermatological, cov tshuaj siv rau hauv txheej nyias nyias rau thaj tsam muaj 2-3 zaug hauv ib hnub, lossis siv rau daim ntaub qhwv cov ntaub nplaum nrog rau daim ntawv thov tom qab rau thaj tsam ntawm daim tawv nqaij. Lub sijhawm tiv thaiv yog 7-14 hnub.

Nyob rau hauv muaj qhov txhab exudate thiab yaig, ua ntej ntxuav nrog kev daws ntawm furatsilina (1: 5000), hydrogen peroxide (3%).

Sab sij huam

Thaum thov cov tshuaj pleev gentamicin, mob ua paug hauv zos (liab, khaus, khaus), ua xua (tawv nqaij ua pob khaus, khaus, urticaria, ua npaws, angioedema, eosinophilia) yog qhov ua tau. Yog tias muaj qhov ua xua tshwm sim, cov tshuaj raug muab tso tseg thiab kho txoj kev kho kom raug pov tseg.

Nrog rau kev siv sab nraud ntawm gentamicin ntev ntev rau ntawm thaj chaw loj ntawm daim tawv nqaij, nws yog qhov yuav tsum tau coj mus rau hauv tus account qhov ua tau rau qhov kev tshem tawm, tshwj xeeb tshaj yog rau cov neeg mob uas mob raum tsis ua haujlwm.

Tom qab pleev cov tshuaj pleev gentamicin, tshwj xeeb nrog kev siv tshuaj pleev ntev rau ntawm qhov mob ntawm qhov chaw loj, ototoxic, vestibular thiab nephrotic muaj peev xwm ua tau.

Kev cuam tshuam nrog lwm yam tshuaj

Nws yuav tsum tsis txhob siv ib txhij nrog lwm cov tshuaj tua kab mob uas muaj cov mob oto- thiab nephrotoxic (streptomycin, kanamycin, florimycin, monomycin, ristamycin), nrog furosemide. Cov kev ua si Gentamicin tsawg zuj zus nyob ntawm qhov pom ntawm Na +, K +, Ca ++, Mg ++ ions, nrog rau ntau tus anions (sulfates, phosphates, nitrates, thiab lwm yam). Muaj cov pov thawj ntawm kev sib koom ua ke ntawm gentamicin nrog dioxidine. Tej zaum siv ua ke nrog corticosteroids.

Hauv cov tshuaj vitro, aminoglycosides tsis ua hauj lwm los ntawm penicillins thiab cephalosporins vim muaj kev sib cuam tshuam nrog ring-lactam nplhaib. Gentamicin yog tsis sib xws nrog heparin, kev daws teeb meem nrog alkaline pH thiab nrog tshuaj uas tsis ruaj khov ntawm acidic pH.

Kev tiv thaiv kev nyab xeeb

Gentamicin sulfate yog ib hom kab mob tsis zoo rau kev kis kab mob lossis tawv nqaij mob.

Kev kho yog ua tiav los ntawm kev tswj hwm ntawm cov tshuaj tua kab mob, vim tias siv tshuaj tua kab mob, nrog rau gentamicin, tuaj yeem ua rau kev loj hlob ntawm cov kab mob tsis txaus, suav nrog rau cov hu ua fungi. Hauv qhov no, ntxiv rau thaum muaj tawv nqaij ua xua, kev ua xua lossis superinfection, kev kho nrog gentamicin yuav tsum muaj kev cuam tshuam thiab kev kho tsim nyog yuav tsum tau nqa tawm.

Yog tias nyob hauv 1 lub lis piam tsis muaj kev kho mob kom zoo, koj yuav tsum sab laj nrog koj tus kws kho mob.

Gentamicin tshuaj pleev tsis pom zoo rau kev siv nrog concomitant systemic kev tswj hwm ntawm aminoglycosides, zoo li hauv cov neeg mob raum tsis ua haujlwm, vim qhov kev pheej hmoo ntawm cov tshuaj lom aminoglycosides nce ntxiv.

Kev siv tshuaj pleev gentamicin hauv kev kho mob ntawm daim tawv nqaij yog cuam tshuam nrog kev pheej hmoo ntawm kev fab tshuaj tsis haum, qhov ntau zaus uas yog li ntawm 1.4%. Txoj kev pheej hmoo ntawm kev rhiab siab ntau zuj zus nrog lub sijhawm siv sijhawm ntev dua. Pawg qhov tseeb raug pom zoo hauv gentamicin thiab lwm yam aminoglycosides, xws li neomycin thiab kanamycin.

Thaum kho thaj chaw loj ntawm daim tawv nqaij, tshwj xeeb tshaj yog rau lub sijhawm ntev lossis nyob ntawm qhov chaw ntawm tawv nqaij, qhov dej noo gentamicin yuav ua rau muaj zog ntxiv. Raws li cov xwm txheej no, tshwj xeeb tshaj yog nyob hauv menyuam yaus, kev ceev faj yuav tsum ua kom tawm dag zog, vim tias qhov kev pheej hmoo ntawm cov kab ke ntawm gentamicin nce ntxiv.

Vim tias muaj qhov thaiv cov hlab hlwb neuromuscular nyob rau hauv aminoglycosides thaum lub cev raug mob, yuav tsum ceev faj rau cov neeg mob myasthenia, Parkinson tus kab mob thiab lwm yam kab mob nrog los ntawm cov leeg tsis muaj zog, nrog rau kev siv lwm cov tshuaj nrog cov nyhuv neuromuscular thaiv tsis tau.

Vim tias muaj cov roj nplaum dawb thiab cov kua roj ua kua, cov roj pleev gentamicin tuaj yeem ua rau txo qis ntawm lub zog ntawm cov hnab looj latex, thiaj li txo qis kev nyab xeeb ntawm kev siv lawv. Qhov no yuav tsum tau txiav txim siab thaum siv tshuaj pleev gentamicin hauv qhov chaw mos lossis qhov quav.

Siv rau cov neeg mob laus yuav tsum tau ceev faj thiab kev tshuaj ntsuam lub raum kev ua haujlwm kom raws sij hawm.

Cuam tshuam rau lub peev xwm tsav tsheb thiab lwm yam uas muaj peev xwm txaus ntshai. Vim tias yuav tshwm sim tsim kev tsis haum thaum siv tshuaj, kev saib xyuas yuav tsum tau saib xyuas thaum tsav tsheb thiab thaum koom nrog kev ua haujlwm uas yuav tsum muaj kev saib xyuas ntau ntxiv.