Cov lus qhia Vazotens rau kev siv, contraindications, phiv, tshuaj xyuas

Qhov kev paub tseeb angiotensin II receptor antagonist (subtype AT1)
Npaj: VAZOTENZ®

Cov tshuaj nquag ntawm cov tshuaj: losartan
Kev saib xyuas ATX: C09CA01
KFG: Angiotensin II receptor antagonist
Cov naj npawb rau npe: LS-002340
Hnub sau npe: 12/08/06
Tswv reg reg. acc .: ACTAVIS hf.

Vazotens tso tawm daim ntawv, ntim tshuaj thiab muaj pes tsawg leeg.

Cov ntsiav tshuaj dawb yog cov puag ncig, biconvex, cim “3L” ntawm ib sab, muaj kev pheej hmoo ntawm ob sab thiab sab txaus ntshai. 1 tab losartan poov tshuaj 50 mg
Cov muaj mob: mannitol, microcrystalline cellulose, croscarmellose sodium, povidone K-30, magnesium stearate, hypromellose 6, titanium dioxide (E171), talc, propylene glycol.
7 Pcs - hlwv (2) - pob khoom los ntawm cardboard.
Cov ntsiav tshuaj dawb yog oval, biconvex, nrog tus qauv hais tias “4L” ntawm ib sab. 1 tab losartan poov tshuaj 100 mg
Cov muaj mob: mannitol, microcrystalline cellulose, croscarmellose sodium, povidone K-30, magnesium stearate, hypromellose 6, titanium dioxide (E171), talc, propylene glycol.
7 Pcs - hlwv (2) - pob khoom los ntawm cardboard.

Cov lus piav qhia ntawm cov tshuaj yog ua raws cov lus qhia raug pom zoo rau kev siv.

Kev Sib Sau thiab daim ntawv ntawm tso tawm

Coated ntsiav tshuaj	1 tab.
losartan poov tshuaj	50 mg
100 mg
tus zam: mannitol, MCC, croscarmellose sodium, povidone K-30, magnesium stearate, hypromellose 6, titanium dioxide (E171), magnesium hydrosilicate (talc), propylene glycol

hauv qhov ncauj tawm 7 pcs., hauv ib pob khoom ntawm cardboard 2 blisters.

Tso tawm daim ntawv thiab muaj pes tsawg leeg

Dosage daim ntawv - coated ntsiav tshuaj:

12.5 mg: puag ncig, convex ntawm ob sab, dawb, cim "1L" rau ntawm ib sab,
25 mg: puag ncig, nkhaus rau ob sab, dawb, cim "2L" rau ntawm ib sab,
50 mg: puag ncig, convex ntawm ob sab, dawb, nrog cov phom sij tom ntej thiab cov kev pheej hmoo ntawm ob sab, cim nrog "3" thiab "L" ntawm ob qho kev pheej hmoo,
100 mg: oval, convex ntawm ob sab, dawb, nrog nqis siab rau ntawm ib sab thiab "4L" cim rau lwm tus, muaj kev pheej hmoo tom qab.

Ntim ntawm cov ntsiav tshuaj: 7 pcs. nyob rau hauv cov hlwv qhwv, nyob hauv pob ntawv qhwv ntawm 2 lossis 4 hlwv, 10 pcs. nyob rau hauv cov hlwv qhwv, nyob hauv pob ntawv qhwv ntawm 1 lossis 3 hlwv, 14 pcs. hauv lub blister, hauv duab los qhia ib pob ntawm 1 lossis 2 hlwv. Txhua pob ntawv kuj muaj cov lus qhia rau kev siv vazotenza.

Cov khoom siv nquag: losartan potassium, hauv 1 ntsiav tshuaj - 12.5 mg, 25 mg, 50 mg lossis 100 mg.

Ntu cov khoom siv: microcrystalline cellulose, hypromellose 6, povidone K-30, croscarmellose sodium, mannitol, magnesium stearate, propylene glycol, talc, titanium dioxide (E171).

Kev piav qhia ntawm daim ntawv tshuaj

50 mg ntsiav tshuaj: puag ncig biconvex ntsiav tshuaj, dawb, coated, nrog tsim qauv ntawm ib sab "3L", nrog kev pheej hmoo ntawm ob sab thiab sab txaus ntshai.

100 mg ntsiav tshuaj: oval biconvex ntsiav tshuaj dawb, dawb, coated, nrog tsim qauv ntawm ib sab "4L".

Cov Tshuaj Hauv Tshuaj

Losartan yog qhov tshwj xeeb kev thaiv ntawm angiotensin II receptors, belongs rau AT pawg₁Cov. Kinase II (qhov muaj roj ntsha tsis sib thooj) tsis inhibit.

Lub ntsiab los ntawm losartan:

txo nyob rau hauv tag nrho peripheral vascular tsis kam, concentration ntawm aldosterone thiab adrenaline nyob rau hauv cov ntshav, ntshav siab, siab nyob rau hauv lub ntsws pulmonary,
tom qab txo nqi
diuretic nyhuv
tiv thaiv kev txhim kho ntawm myocardial hypertrophy,
ua kom ib ce muaj zog thev ntxiv thaum lub siab tsis ua hauj lwm.

Vasotens muaj kev cuam tshuam hypotensive tom qab ib koob nkaus xwb (manifested raws li txo qis systolic thiab diastolic siab), nce mus txog qhov siab kawg tom qab 6 teev, tom qab ntawd cov nyhuv txo qis dua 24 teev.

Qhov siab tshaj plaws hypotensive nyhuv ntawm vasotenza kev loj hlob 3-6 lub lis piam tom qab pib ntawm kev coj.

Cov Tshuaj Pharmacokinetics

Losartan nrawm nrawm los ntawm lub plab zom mov. Bioavailability yog kwv yees li 33%. T_max (lub sijhawm kom ncav cuag qhov siab tshaj plaws ntawm cov quav) - 60 feeb.

Losartan yauv lub txiaj ntsig ntawm thawj kev nkag mus rau ntawm daim siab, cov metabolism hauv lub cev tshwm sim los ntawm carboxylation nrog kev koom tes ntawm CYP2C9 isoenzyme, thiab ib qho metabolite nquag tau tsim. T_max nquag metabolite - 3-4 teev, qhov degree ntawm nws khi rau cov ntshav plasma protein - 99%.

T_1/2 (ib nrab-lub neej) ntawm ib yam khoom uas yog nyob rau hauv thaj tsam li ntawm 1.5 mus rau 2 teev, nws lub cev qhov tseem ceeb yog 6-9 teev. Txog 35% ntawm qhov koob tshuaj raug tawm hauv cov zis, los ntawm txoj hnyuv - kwv yees li 60%.

Nrog rau mob ntsws ua rau lub siab, cov ntshav plasma concentration ntawm losartan nce ntau.

Vazotens, cov lus qhia rau kev siv: txoj kev thiab ntau npaum li cas

Cov ntsiav tshuaj vazotens yuav tsum noj qhov ncauj 1 zaug nyob rau ib hnub (tsis hais qhov siv tshuaj npaum li cas). Lub sijhawm noj mov tsis muaj teeb meem.

Txoj cai muab tshuaj rau vasotenza:

arterial hypertension: qhov nruab nrab kho tshuaj yog 50 mg, kom ua tiav cov txiaj ntsig zoo dua, nws muaj peev xwm nce qhov koob ntau dua 100 mg, yog tias tsim nyog, koob tshuaj txhua hnub tuaj yeem faib ua 2 koob. Thawj koob tshuaj rau cov neeg mob uas tau txais kev tso tshuaj siab ntawm diuretics yog 25 mg.
lub plawv tsis ua hauj lwm: thawj koob tshuaj yog 12,5 mg, tom qab ntawd nws tau nce ntawm ncua sijhawm 1 lub lis piam, thawj zaug txog 25 mg, tom qab ntawd nce txog 50 mg. Qhov nruab nrab ntawm cov tshuaj txij nkawm yog 50 mg.

Ntawm cov koob tshuaj qis dua, vasotens yog kho rau cov neeg mob uas lub siab ua haujlwm tsis txaus siab, suav nrog mob qog.

Sab sij huam

Feem ntau, cov vasotens tau pom zoo zoo, muaj kev phiv tshuaj yog hloov mus rau qhov xwm txheej thiab tsis tas yuav tsum tsis ua haujlwm ntxiv rau kev kho.

Cov tshuaj phiv:

los ntawm cov hlab plawv system: orthostatic hypotension (koob tshuaj-tiv thaiv), palpitations, arrhythmias, bradycardia, tachycardia, angina pectoris,
los ntawm cov leeg hlwb: feem ntau (≥ 1%) - kiv taub hau, qaug zog, asthenia, pw tsaug zog, mob taub hau, tsis tshua muaj (

Cev xeeb tub thiab lactation

Tsis muaj ntaub ntawv qhia txog kev siv losartan thaum cev xeeb tub. Txawm li cas los xij, nws paub tias cov tshuaj uas cuam tshuam ncaj qha rau renin-angiotensin system, thaum siv nyob rau zaum ob thiab thib peb lub cev xeeb tub, tuaj yeem ua rau muaj kev txhim kho lossis kev tuag ntawm kev loj hlob ntawm tus me nyuam hauv plab. Yog li, yog tias muaj menyuam hauv plab, Vazotenza ® yuav tsum tsis ua mus ntxiv tam sim ntawd.

Thaum lub sijhawm muab tshuaj rau lactation, ib qho kev txiav txim siab yuav tsum raug txiav txim siab kom tsis pub niam mis lossis kom tsis txhob muaj kev kho mob nrog Vazotens ®.

Kev sib txuam

Yuav tau muab tshuaj nrog lwm cov tshuaj tiv thaiv antihypertensive.

Tsis muaj qhov sib cuam tshuam hauv chaw kho mob nrog hydrochlorothiazide, digoxin, cov tshuaj tiv thaiv tsis tseem ceeb, cimetidine, phenobarbital tau sau tseg.

Hauv cov neeg mob lub cev qhuav dej (ua ntej kho nrog ntau cov tshuaj diuretics), qhov txo qis hauv ntshav siab tuaj yeem tshwm sim.

Txhim kho (ob leeg) cov nyhuv ntawm lwm cov tshuaj tiv thaiv kabmob (diuretics, beta-blockers, sympatholytics).

Nce kev pheej hmoo ntawm hyperkalemia thaum siv ua ke nrog potassium-sparing diuretics thiab poov tshuaj npaj.

Tsuas tshuaj thiab tswj hwm

Sab hauv tsis hais txog ntawm cov noj mov. Tshaj tawm ntawm kev pub nkag - 1 zaug nyob rau ib hnub.

Nrog rau cov hlab ntsha o, qhov nruab nrab txhua hnub koob yog 50 mg. Qee qhov xwm txheej, kom ua tiav cov txiaj ntsig ntau dua, cov koob tshuaj tau nce mus txog 100 mg hauv 2 koob tshuaj lossis 1 zaug ib hnub.

Thawj koob tshuaj rau cov neeg mob plawv yog 12,5 mg ib hnub ib zaug. Raws li txoj cai, koob tshuaj tau nce nrog lub sijhawm ib asthiv (i.e. 12.5, 25 thiab 50 mg / hnub) mus rau kev tswj hwm ib nrab ntawm 50 mg ib hnub ib zaug, nyob ntawm tus neeg mob lub siab ntev rau cov tshuaj.

Thaum muab tshuaj rau cov neeg mob uas tau txais cov tshuaj diuretics hauv kev txhaj tshuaj siab, thawj zaug koob tshuaj Vazotens ® yuav tsum txo kom tsawg dua 25 mg ib hnub ib zaug.

Cov neeg mob lub siab ua haujlwm tsis zoo yuav tsum tau txhaj tshuaj Vazotenza qis dua.

Hauv cov neeg laus uas muaj mob, thiab rau cov neeg mob uas lub raum tsis zoo, suav nrog cov neeg mob lim ntshav, tsis tas yuav kho qhov pib noj tshuaj.

Kev siv kho cov menyuam yaus

Kev nyab xeeb thiab kev ua tau zoo ntawm cov tshuaj hauv cov menyuam yaus tseem tsis tau tsim.

Cov lus qhia tshwj xeeb

Nws yog ib qho tsim nyog yuav tau kho lub cev qhuav dej ua ntej sau ntawv yuav siv cov tshuaj Vazotens ® lossis pib kho nrog kev siv tshuaj nyob rau hauv qis dua.

Cov tshuaj uas cuam tshuam rau renin-angiotensin system tuaj yeem nce cov ntshav urea thiab cov ntshav creatinine hauv cov neeg mob uas muaj ob leeg lub raum mob stenosis lossis stenosis ntawm ib lub raum leeg.

Thaum lub sijhawm kev kho mob, cov concentration ntawm cov poov tshuaj nyob rau hauv cov ntshav yuav tsum tau saib xyuas tsis tu ncua, tshwj xeeb tshaj yog nyob rau cov neeg laus, nrog lub raum tsis ua haujlwm.

Txee lub neej ntawm tshuaj Vazotens ®

co ntsiav tshuaj 12,5 mg - 3 xyoos.

co ntsiav tshuaj 25 mg - 3 xyoos.

co ntsiav tshuaj 50 mg - 3 xyoos.

co ntsiav tshuaj 100 mg - 3 xyoos.

Tsis txhob siv tom qab hnub tas sij hawm qhia ntawm pob.

Pharmacological kev txiav txim siab ntawm vasotens

Tshwj xeeb angiotensin II receptor antagonist (subtype AT1). Nws inhibits kinase II, ib qho enzyme uas rhuav tshem bradykinin. Txo OPSS, cov ntsiab lus hauv cov ntshav adrenaline thiab aldosterone, cov ntshav siab, ntshav siab hauv cov ntsws ntsig. Txo cov khoom tom qab, muaj cov nyhuv diuretic. Tiv thaiv kev txhim kho ntawm myocardial hypertrophy, nce kev qoj ib ce ua siab ntev rau cov neeg mob plawv tsis ua haujlwm.
Tom qab siv ib zaug xwb, qhov ua rau hypotensive (systolic thiab diastolic ntshav siab) nce mus txog qhov siab kawg tom qab 6 teev, tom qab ntawd maj mam txo qis hauv 24 teev.
Qhov siab tshaj plaws ntawm kev ua haujlwm yog tau tiav 3-6 lub lis piam tom qab pib tshuaj.

Vazotens: tus nqi hauv cov khw muag tshuaj online

Vazotens 12,5 mg coated ntsiav tshuaj 30 pcs.

Vazotens 50 mg zaj duab xis-coated ntsiav tshuaj 30 pcs.

VAZOTENZ 50mg 30 Pcs. txheej ntsiav tshuaj

Vazotens tab. PO 50mg n30

Vazotens tab. PO 100mg n30

Vazotens 100 mg zaj duab xis-coated ntsiav tshuaj 30 pcs.

VAZOTENZ 100mg 30 Pcs. txheej ntsiav tshuaj

VAZOTENZ N 100mg + 25mg 30 Pcs. zaj duab xis-ntsiav tshuaj ntsiav tshuaj

Kev Kawm: Rostov State Medical University, tshwj xeeb "General Tshuaj".

Cov ntaub ntawv hais txog cov tshuaj raug muab dav dav, muab rau kev qhia tawm thiab tsis hloov chaw cov lus qhia. Kev siv tshuaj rau tus kheej yog qhov txaus ntshai rau kev noj qab haus huv!

Txhawm rau hais txawm tias cov lus luv thiab yooj yim, peb siv 72 leeg leeg.

Cov tib neeg uas tau noj tshais ua ntu zus feem ntau yog cov muaj rog.

Tus neeg muaj kev kawm paub tsis yooj yim rau cov kab mob hlwb. Cov kev txawj ntse ua haujlwm koom nrog kev tsim cov ntaub so ntswg ntxiv los txhawb rau cov neeg mob.

Cov kws kho hniav tau tshwm sim tsis ntev los no. Rov qab rau hauv lub xyoo pua puv 19, nws yog lub luag haujlwm ntawm tus kws tu plaub hau kom rub tawm cov hniav mob.

Yog tias koj lub siab ua haujlwm, kev tuag yuav tshwm sim hauv ib hnub.

Raws li ntau tus kws tshawb fawb, cov vitamins complex yog qhov tsis muaj txiaj ntsig rau tib neeg.

Thaum lub neej, tus neeg nruab nrab tsim tawm tsis tsawg tshaj li ob lub pas dej loj uas muaj qaub ncaug.

Raws li kev txheeb cais, nyob rau hnub Monday, kev pheej hmoo ntawm nraub qaum nce ntxiv li 25%, thiab kev pheej hmoo ntawm mob plawv - los ntawm 33%. Kom ceev faj.

Raws li kev tshawb fawb los ntawm WHO, kev sib tham ib nrab hnub nyob rau ntawm lub xov tooj ntawm tes tau qhov feem ntau ntawm kev txhim kho lub hlwb lub hlwb los ntawm 40%.

Yog tias koj luag nyav tsuas yog ob zaug ib hnub, koj tuaj yeem txo cov ntshav siab thiab txo qhov kev pheej hmoo ntawm lub plawv thiab mob nkees.

Qhov nruab nrab lub neej ntawm cov laug yog tsawg dua ntawm txoj cai.

Muaj ntau cov kev kho mob nthuav tawm heev, xws li kev siv khoom tsis nco qab ntawm cov khoom. Hauv plab ntawm ib tus neeg mob uas tau mob los ntawm tus txiv neej no, 2500 cov khoom txawv teb chaws tau pom.

Plaub qho ntawm chocolate tsaus muaj txog ob puas calories. Yog li yog tias koj tsis xav tau zoo dua, nws zoo dua tsis txhob noj ntau tshaj li ob lobules ib hnub.

Kev ua haujlwm uas ib tus neeg tsis nyiam yuav muaj kev phom sij rau nws lub siab ntau dua li qhov uas tsis muaj haujlwm hlo li.

Tib neeg cov pob txha yog plaub zaug muaj zog dua li cov pob zeb.

Thawj nthwv dej ntawm paj los txog rau qhov kawg, tab sis cov ntoo tawg paj yuav hloov los ntawm cov nyom los pib thaum lub Rau Hli, uas yuav cuam tshuam rau cov neeg tsis haum tshuaj.

Dosage thiab txoj hauv kev ntawm kev tswj hwm tshuaj.

Cov tshuaj yog noj ntawm qhov ncauj, tsis hais txog ntawm cov pluas noj, qhov ntau zaus ntawm kev tswj hwm - 1 zaug / hnub.
Nrog rau cov hlab ntsha o, qhov nruab nrab txhua hnub koob yog 50 mg. Qee qhov xwm txheej, kom ua tiav cov txiaj ntsig ntau dua, cov koob tshuaj tau nce mus txog 100 mg hauv 2 koob lossis 1 teev / hnub.
Thaum muab tshuaj rau cov neeg mob uas tau txais cov tshuaj diuretics hauv kev txhaj tshuaj siab, thawj zaug koob tshuaj Vazotens yuav tsum raug txo mus rau 25 mg 1 zaug / hnub.
Thawj koob tshuaj rau cov neeg mob plawv yog 12,5 mg 1 zaug / hnub. Raws li txoj cai, koob tshuaj nce nrog lub lis piam sib piv (i.e. 12,5 mg / hnub, 25 mg / hnub thiab 50 mg / hnub) rau ib qho nruab nrab tswj kev kho mob ntawm 50 mg 1 zaug / hnub, nyob ntawm tus neeg mob lub siab ntev rau cov tshuaj.
Cov neeg mob uas muaj lub siab ua haujlwm tsis zoo (nrog rau mob qog ntshav) yuav tsum yog vasotenz qis dua.
Hauv cov neeg mob laus, thiab rau cov neeg mob uas lub raum tsis zoo, suav nrog cov neeg mob lim ntshav, tsis tas yuav hloov kho qhov mob thaum xub thawj.