Liptonorm: tus nqi ntawm cov tshuaj hauv cov khw muag tshuaj, cim thiab tshuaj xyuas

Qhov lipid-txo cov tshuaj no yog koom nrog pawg statinsCov. Nws cov tshuab ntawm kev ua yog raws li kev txwv tsis pub ua haujlwm ntawm 3-hydroxy-3-methylglutarylcoenzyme A lossis HMG-CoA, zoo li reductase, enzymeuas catalyzes txheej txheem kev hloov pauv mus ua lwm yam mevalonic acidCov. Xws li kev hloov pauv tshwm sim nyob rau theem pib ntawm synthesis. rojCov. Kev siv cov tshuaj tiv thaiv kev tsim cov roj cholesterol thiab txo nws cov ntsiab lus hauv qhov muaj pes tsawg leeg ntshav.

Cov kev ua rau lub ntsej muag antisclerotic ntawm Liptonorm cuam tshuam nrog nws cov nyhuv ntawm phab ntsa ntawm cov hlab ntsha thiab cov ntshav sib xyaw. Nyob rau tib lub sijhawm, kev tsim cov isoprenoids, kev loj hlob ntawm tes ntawm sab hauv vascular membrane, yog suppressed. Cov kev kho kuj tseem txhim kho endothelium - cov tub rog nyob ntawm lub xeev cov roj ntsha, txo cov roj cholesterol, triglycerides, qis lipoproteins thiab apolipoprotein B. Ib qho nce ntawm HDL cov cholesterol thiab apolipoprotein A tau sau tseg.

Cov tshuaj yog tus cwj pwm los ntawm kev nqus siab. Qhov siab tshaj plaws ntawm cov tshuaj pom pom tom qab 1-2 teev thiab yuav ua raws tus tub los ntxhais, muaj cov kab mob ntev, noj, sij hawm ntawm ib hnub, thiab lwm yam.

Liptonorm muaj qhov ua qis qis ntawm bioavailability vim yog lub zog presystemic metabolism hauv nyob rau hauv lub plab zom mov thaum lub sij hawm hla los ntawm lub siab. Hauv lub cev, cov tshuaj tau hloov mus ua ntau yam metabolites, kev tshem tawm ntawm uas thiab ib feem ntawm cov tsis hloov pauv tshwm sim nrog cov kua tsib thiab tso zis.

Kev taw qhia rau kev siv Liptonorm

Cov tshuaj yog kws kho nyob rau hauv kev kho mob ntawm:

thawj hypercholesterolemia,
sib xyaw hyperlipidemia,
heterozygous thiab homozygous tsev neeg hypercholesterolemia, raws li kev txuas rau cov khoom noj muaj txiaj ntsig.

Cov Yuav Tsum Muaj

Kev siv cov tshuaj yog contraindicated nyob rau hauv:

rhiab rau nws lub Cheebtsam,
mob siab thiab mob raum,
lactation, cev xeeb tub,
Cov neeg mob muaj hnub nyoog qis dua 18 xyoos.

Kev ceev faj yog yuav tsum muaj rau cov kab mob siab, ntshav tsis txaus, qee qhov endocrine thiab metabolism tsis ua hauj lwm, haus dej cawv, mob hnyav, mob ntshav tawm, tswj tsis tau tus mob, ua rau muaj mob loj thiab khiav haujlwm.

Sab sij huam

Thaum kho nrog Liptonorm, cov kev mob tshwm sim tuaj yeem tsim kho uas tuaj yeem cuam tshuam cov kev ua haujlwm ntawm cov hlab ntsha hlwb, hlab plawv, ua pa, hematopoietic, cov kab mob genitourinary, kev paub ntawm lub plab, thiab cov leeg ua haujlwm.

Cov kev tsis sib xws muaj peev xwm nthuav qhia lawv tus kheej nrog cov tsos mob: insomnia, kiv taub hau, mob taub hau, asthenic mob ntsws, cov lus hais dav dav, mob tsis txaus ntseeg, suab nrov hauv lub pob ntseg, lub cev qhuav ntawm lub qhov muag, cov ntshav tawm ntawm qhov muag, lag ntseg, mob ntswsmob hauv siab mob ntsws, rhinitis.

Qee zaum cov neeg mob tshwm sim phiv ntawm daim tawv nqaij ua raws li: alopecia, xerodermance tawm hws,eczema, seborrhea.

Ua xua tuaj yeem tshwm sim. khaus tawvxoo pob, chwv dermatitis, urticaria thiab lwm yam kev ua txhaum.

Thaum lub sijhawm kuaj ntshav kuaj mob, nws muaj peev xwm txiav txim siab hyperglycemia, ntshav qab zib tsawg, ua kom muaj cov ntshiab si creatine phosphokinase, albuminuria.

Lwm qhov kev ua tsis tau zoo yog: nce phaus, mastodynia, gynecomastia thiab aggravation mob gout.

Liptonorm, cov lus qhia rau kev siv (Txoj kev thiab ntau npaum li cas)

Ua ntej pib siv cov tshuaj no, tus neeg mob yuav tsum pauv mus rau kev noj haus, uas yuav muab qhov txo qis hauv cov ntsiab lus ntawm lipids hauv cov ntshav. Yuav tsum ua raws li cov kev cai noj haus zoo rau txhua lub sijhawm ntawm txoj kev kho.

Raws li cov lus qhia, Liptonorm ntsiav tshuaj noj ntawm qhov ncauj, tsis hais txog kev noj zaub mov thiab lub sijhawm ntawm hnub, tab sis thaum teev.

Nws raug nquahu kom pib kho nrog kev siv tshuaj txhua hnub ntawm 10 mg yuav tsum noj ib zaug ib hnub. Tom qab qee lub sijhawm, xaiv cov koob tshuaj yog nqa tawm ntawm tus kheej, coj mus rau hauv tus account lub yam ntxwv ntawm tus neeg mob lub cev thiab cov ntsiab lus roj. Hloov cov koob tshuaj yog ua tau tsis pub ntau tshaj 1 zaug hauv ib hlis. Qhov siab tshaj plaws tau tso cai rau noj txhua hnub yog 80 mg.

Noj ntau dhau

Yog hais tias noj ntau dhau, cov tsos mob cuam tshuam nrog phiv tuaj yeem loj hlob, tab sis nrog muaj mob hnyav dua.

Tshwj xeeb tshuaj tiv thaiv kab mob rau cov tshuaj no tsis muaj nyob, yog li cov kev kho mob tshwm sim, kev ntsuas yog tsim los txhawb txoj haujlwm ntawm cov haujlwm tseem ceeb ntawm cov kabmob thiab tiv thaiv kev nqus ntxiv ntawm cov tshuaj, piv txwv li, lub plab zom mov, sivtshuab txais carbonCov. Nyob rau tib lub sijhawm hemodialysis tsis qhia kev ua hauj lwm zoo.

Kev sib txuam

Yog tias muab thooj txhij ua ke nrog cov tshuaj no Cyclosporine, Fibrates, Erythromycin, Clarithromycin,NicotinamideTxij li thaum siv cov tshuaj tiv thaiv kab mob thiab tshuaj tiv thaiv kab mob yog azoles, qhov kev nce siab ntawm nws cov tshuaj nquag yuav xav tau - atorvastatinnyob rau hauv muaj pes tsawg leeg ntshav ntshav.

Kev sib xyaw ntawm atorvastatin thiab antacids, protease inhibitors, uas yog, tshuaj tiv thaiv ntawm cytochrome P450 CYP3A4, tuaj yeem ua rau nce qhov tshuaj ntawm cov tshuaj hauv ntshav ntshav.

Kev siv tshuaj nrog Digoxin nce nws cov kev xav hauv lub cev, nrog rau kev txwv tsis pub muaj qhov ncauj, uas suav nrog norethindronethiab ethinyl estradiol.

Kauj ruam nce lipid-txo cov nyhuv, thiab Warfarin tuaj yeem txo lub sijhawm prothrombin thaum pib ntawm kev kho, uas yuav tsum muaj kev soj ntsuam txhua lub sijhawm ntawm qhov ntsuas no.

Kev siv cov kua txiv kab ntxwv tuaj yeem ua rau muaj zog ntau dua ntawm atorvastatin thaum kho mob, yog li koj yuav tsum tsis lees txais nws.

Tso tawm daim ntawv thiab muaj pes tsawg leeg

Daim ntawv noj tshuaj - cov ntsiav tshuaj muaj xim: puag ncig, convex ntawm ob sab, dawb, ntawm qhov tawg - yuav luag dawb lossis dawb (14 pcs. Hauv ib lub hlwv, 2 lub hlwv hauv ib lub thawv ntawv).

Cov tshuaj nquag: atorvastatin (nyob rau hauv daim ntawv ntawm calcium ntsev), nws cov ntsiab lus hauv 1 ntsiav tshuaj yog 10 lossis 20 mg.

Ntu cov khoom siv: kaum ob 80, lactose, hydroxypropyl cellulose, microcrystalline cellulose, croscarmellose, calcium carbonate, magnesium stearate, polyethylene glycol, titanium dioxide, hydroxypropyl methyl cellulose.

Cov lus qhia rau kev siv Liptonorm: txoj kev thiab ntau npaum li cas

Ua ntej yuav sau cov tshuaj, tus neeg mob hloov mus rau cov khoom noj kom tsim nyog, uas ua kom cov ntshav lipids (nws yuav tsum pom thaum lub sijhawm kho tag nrho).

Raws li cov lus qhia, Liptonorm yuav tsum tau noj qhov ncauj 1 zaug nyob rau ib hnub, tsis hais txog kev noj zaub mov, tab sis tib lub sijhawm txhua hnub.

Thawj koob tshuaj feem ntau yog 10 mg. Hauv lub neej tom ntej, cov qib siab zoo tshaj plaws tau xaiv ib tus zuj zus, raws li cov ntsiab lus ntawm cov roj lipoprotein tsawg, qhov hnyav ntawm cov kab mob thiab cov txiaj ntsig ntawm kev kho. Cov koob tshuaj yuav tsum tau hloov tsawg kawg yog 4 lub lis piam sib nrug.

Qhov tshuaj tso cai siab tshaj plaws txhua hnub yog 80 mg hauv 1 koob tshuaj.

Sab sij huam

Zaus ntawm cov kev mob tshwm sim: feem ntau - hauv ntau dua 2% ntawm tus neeg mob, tsis tshua muaj - hauv tsawg dua 2% ntawm cov neeg mob.

Lub hauv nruab nrab hauv lub paj hlwb: feem ntau kiv taub hau thiab pw tsaug zog, tsis tshua tsaug zog, npau suav phem, asthenic syndrome, lub siab lub ntsws ua haujlwm, hyperkinesis, paresthesia, malaise, tsis nco qab, mob taub hau, poob siab, amnesia, ataxia, hyperesthesia, ntsej muag txhawm chim, peripheral neuropathy
Cov kabmob hauv lub cev: muaj kev tsis txaus siab ntawm kev pab, kev hloov pauv ntawm saj, tsis hnov tsw, parosmia (poob ntawm tsis hnov tsw), tinnitus, lag ntseg, amblyopia, qhuav conjunctiva, ntsej muag daj, mob ntshav hauv lub qhov muag,
Cov hlab plawv: feem ntau - mob hauv siab, tsis tshua muaj - mob taub hau, nce ntshav siab, vasodilation, arrhythmia, postural hypotension, angina pectoris, palpitations, phlebitis,
Kab mob ntsws: feem ntau - rhinitis thiab mob ntsws, tsis tshua muaj - ua tsis taus pa, tso zis rau txoj hlab ntshav, mob ntsws asthma, mob ntsws,
Cov kab mob hauv lub plab: feem ntau - cheilitis, stomatitis, lub qhov ncauj qhuav, cov pos hniav los ntshav, ua paug thiab mob txhab ntawm lub qhov ncauj ntawm qhov ncauj, txhaws, mob plab, mob plab, mob plab, mob lub siab, mob duav, xeev siab, cem quav lossis zawv plab, tsis nco qab lossis nce siab, mob plab, melena, ntuav, dysphagia, gastroenteritis, esophagitis, tenesmus, pancreatitis, mob duodenal, mob rau daim tawv nqaij, ua rau lub siab ua haujlwm tsis zoo, mob siab, cholestatic daj ntseg, lub qhov ncauj tawm los,
Musculoskeletal system: feem ntau mob caj dab, tsis tshua muaj tus kab mob bursitis, mob leeg ntawm lub cev, mob myopathy, myositis, mob caj dab, mob caj dab, mob sib khuav, leeg mob caj dab, leeg mob leeg rau leeg, mob ntshav qab zib, mob leeg ntshav, mob rwj
Hematopoietic system: lymphadenopathy, ua haujlwm tsis txaus, thrombocytopenia,
Cov kab mob genitourinary: feem ntau - peripheral edema, urogenital mob, tsis tshua muaj - dysuria (suav nrog tso zis los yog tso zis tsis nco qab lawm, mob leeg, tso zis tseem ceeb, pollakiuria), nephrourolithiasis, hematuria, nephritis, epididymitis, metrorrhagia, ua txhaum ntawm chaw mos los ntshav ejaculation, tsawg libido, impotence,
Dermatological tshua: feem ntau - nce tawm hws, xeroderma, eczema, ecchymosis, seborrhea, petechiae, alopecia,
Kev tsis haum tshuaj: feem ntau - sib chwv dermatitis, tawv nqaij ua pob khaus thiab khaus, tsis tshua muaj - ntsej muag o, anaphylaxis, angioedema, urticaria, photosensitivity, Stevens-Johnson syndrome, erythema multiforme, tshuaj lom neeg mob lom hauv lub cev,
Kev ntsuas qhov ntsuas: tsis tshua muaj - albuminuria, hypoglycemia, hyperglycemia, nce kev ua si ntawm alkaline phosphatase, serum creatine phosphokinase, alanine aminotransferase (ALT) thiab aspartate aminotransferase (AST),
Lwm yam: tsis tshua muaj - hnyav nce, exacerbation ntawm gout, mastodynia, gynecomastia.

Vim li cas Liptonorm raug muab tshuaj rau cov leeg ntshav?

Cov neeg feem ntau raug kev txom nyem los ntawm vascular pathologies. Txhawm rau tshem tawm lawv, kho cov txheej txheem nyuaj yog muaj, uas suav nrog kev noj tshuaj. Tswj cov txiaj ntsig tau txais thaum kho nrog tshwm sim nrog kev siv Liptonorm.

Kev siv Liptonorm yuav pab txhawb qhov txiaj ntsig tau txais hauv kev kho mob vascular pathologies.

Pharmacological kev txiav txim ntawm Liptonorm

Cov tshuaj yog coj los txo qhov kev kub siab ntawm cov lipoproteins uas tsis muaj ntau.

Qhov siab tshaj plaws ntawm cov tshuaj Liptonorm hauv cov ntshav pom nyob rau 1-2 teev tom qab noj tshuaj.

Vim tias lawv, muaj kev ua txhaum ntawm cov ntshav ncig thiab nqaim ntawm cov lumen ntawm cov hlab ntsha, tshwm sim los ntawm cov kev ua haujlwm nquag ntawm cov rog ntawm cov phab ntsa. Cov tshuaj txo qis lipid cov ntsiab lus hauv cov ntshav plasma, yog li ntawd, nws pab kom tsis txhob muaj kev loj hlob ntawm cov hlab ntsha tawg, myocardial infarction thiab lwm yam teeb meem.

Kev noj tshuaj yuav pab ua kom lub cev sib luag ntawm cov ntshav thiab txhim kho kev mob ntawm cov phab ntsa ntawm cov hlab ntsha los ntawm sab hauv.

Cov cuab yeej muaj cov tshuaj tiv thaiv kev ua qaj thiab ua kom lub zog. Nws cov txiaj ntsig zoo nyob hauv nws lub peev xwm los cuam tshuam cov cholesterol hauv cov neeg mob uas raug kev txom nyem los ntawm caj ces pathologies.

Qhov nqus ntawm cov tshuaj tshwm sim dhau los ntawm cov phab ntsa ntawm cov plab hnyuv siab rau lub plab zom mov. Qhov siab tshaj plaws ntawm cov kev ua kom nquag plias hauv cov ntshav tau pom tias 1-2 teev tom qab noj tshuaj. Qhov tshwm sim ntawm kev kho mob kav rau 20-30 teev. Feem ntau ntawm cov tshuaj tawm hauv cov kua tsib, ib qhov nqi - nrog tso zis.

Feem ntau ntawm cov tshuaj tawm hauv cov kua tsib, qee qhov nyiaj - nrog tso zis.

Thov

Ua ntej pib kev kho mob, tus neeg mob yuav tsum hloov mus rau kev noj zaub mov kom zoo, vim tias qib cov lipids hauv cov ntshav ntshav yuav tsawg. Qhov kev noj haus yuav tsum tau pom thoob plaws tag nrho lub sijhawm noj cov tshuaj. Tus neeg mob yuav tsum siv cov tshuaj txhua txhua hnub rau 1 ntsiav tshuaj tib lub sijhawm, tsis hais txog kev noj zaub mov. Thawj qhov tshuaj yog 10 mg.

Nws tuaj yeem hloov pauv raws tus neeg tus yam ntxwv ntawm tus neeg mob, qhov mob hnyav ntawm cov kab mob thiab hloov pauv ntawm cov concentration ntawm cov rog. Cov koob tshuaj tau tso cai hloov pauv 1 zaug hauv 4 lub lis piam. Qhov ntau npaum li cas ntawm cov tshuaj ib hnub yuav tsum tsis pub ntau dua 80 mg.

Ua ntej pib kho Liptonorm, tus neeg mob yuav tsum hloov mus rau kev noj haus uas pab txo qis plasma lipids.

Cov lus qhia tshwj xeeb

Cov ntaub ntawv hais txog cov nyhuv ntawm lipid-txo qis tshuaj ntawm kev tswj hwm thauj tsis muaj. Thaum kho, koj yuav tsum tau ntsuas tsis tu ncua thiab kuaj xyuas lub cev ua haujlwm.

Thaum muaj teeb meem tshwm sim, txoj kev kho yog tso tseg.

Kev siv dej cawv thiab tshuaj ib txhij ua rau lub txim tsis zoo.

Kev siv dej cawv thiab Liptonorm tib lub sijhawm tuaj yeem ua rau lub txim tsis zoo.

Yeeb tshuaj sib cuam tshuam

Kev nce ntxiv ntawm atorvastatin ntshav ntau ntxiv tshwm sim vim nws ib txhij tswj hwm nrog cov tshuaj tiv thaiv kab mob, cyclosporins, tshuaj tua kab mob, erythromycin, clarithromycin, thiab protease inhibitors.

Kev nce ntxiv hauv cov ntsiab lus ntawm Liptonorm hauv cov ntshav plasma tshwm sim vim nws qhov kev tswj hwm ib txhij nrog Erythromycin.

Kev kho kom zoo dua qub yog tias koj siv cov tshuaj nrog Colestipol ua ke. Cov tshuaj ua kom nquag muaj zog ua rau cov tshuaj digoxin ntau ntxiv thaum noj tib lub sijhawm.

Cov Cai Siv Tshuaj So

Cov tshuaj muaj peev xwm yuav tau ntawm txhua lub tsev muag tshuaj yog tias muaj ntawv sau los ntawm cov kws khomob tshwjxeeb.

Tus nqi ntawm lub cuab yeej yog nyob ntawm txoj cai nqe ntawm lub tsev muag tshuaj thiab qhov nruab nrab yog 238 rubles.

Yog tias tsim nyog, cov tshuaj raug hloov nrog cov tshuaj zoo sib xws:

Lipoford
Atom
Vazator,
Thorvakard
Atorvastatin,
Tub los ntxhais,
Atocord.

Tus kws kho mob xaiv cov nyiaj. Txhawm rau tsis txhob ua rau lub xeev ntawm kev noj qab haus huv, nws tsis pom zoo kom hloov nws tus kheej ntawm txoj kev kho mob.

Mikhail, 35 xyoo, Stavropol: “Kuv tau siv Liptonorm thaum qhov kev kuaj pom pom tias muaj cov roj (cholesterol) hauv cov ntshav ntau txaus. Tsis muaj cov kev mob tshwm sim, nrog rau cov txiaj ntsig ntawm kev kho mob. Tus kws kho mob khaws tau ib qho analog uas tig tau los ua kom zoo dua. Kuv tau siv nyiaj tas li, yog li kuv tsis qhia nej kom siv nyiaj. "

Angelina, hnub nyoog 47 xyoo, Moscow: “Kuv tau tawm tsam ntau txoj leeg ntshav tau ntev. Cov tshuaj tau tawm los kho tus kab mob. Thawj thawj hnub ntawd tsis hnov qab, tab sis tom qab ntawd nws txhua yam ploj mus. Kuv tau tshem ntawm cov tsos mob tsis zoo, thiab qhov hnyav hauv kuv txhais ceg. Tus nqi yog tau rau kuv. Tsis muaj kev mob tshwm sim. Kuv pom zoo kom txhua leej txhua tus, vim tias txoj kev daws tau zoo. "

Varvara, 33 xyoo, Krasnoyarsk: “Cev xeeb tub tau dhau los ua qhov hnyav tshaj thiab ua rau leeg ntshav tsis huv. Tus kws kho mob tau sau cov tshuaj no, tab sis ua ntej ntawd, rau ib hlis kuv ua raws li kev noj haus uas tshwj xeeb tuaj tos. Nkees, kev nyuaj siab, thiab ceg mob zoo tom qab 2 lub lis piam tom qab thawj koob tshuaj. Tsis pom qhov ua tsis zoo ntawm lub cev. Lub cuab yeej siv tau zoo, txawm tias qhov txiaj ntsig xav tau tos. "

Stanislav, 53 xyoo, Yaroslavl: “Qhov teeb meem nrog cov hlab plawv plawv ua rau xav tau kev kho mob nyuaj. Lub sijhawm tiv thaiv yog kwv yees li ib hlis. Muaj ntau yam tshwm sim, tab sis kuv tsis xav ntawm kuv tus kheej. Cov tshuaj yog pheej yig, thiab nws cov hauj lwm zoo tuaj yeem pom tom qab ob peb hnub ntawm kev txais neeg mob. "

Liptonorm - ib qho tshuaj lipid-txo cov tshuaj zoo

Liptonorm yog ib qho ntawm lipid-txo cov tshuaj ntawm statin pawg. Lub hauv paus ua haujlwm tseem ceeb yog atorvastatin tivthaiv, cov nyhuv ntawm uas yog los inhibit qhov kev ua ntawm reductase.

Qhov tshuaj tiv thaiv no tau txheeb rau theem pib ntawm cov roj ntsha ua kom sib haum hauv lub cev, thiab Liptonorm inhibits cov txheej txheem no, vim qhov ntawd ua rau cov qib roj cholesterol hauv cov ntshav qis.

Xuas

Thaum siv sab hauv, qhov nqus ntawm Liptonorm yog qhov ntau. Qhov siab tshaj plaws nyob rau hauv cov ntshav yog tom qab 2 teev. Noj ib nyuag txo qhov ntev thiab qhov nrawm ntawm kev nqus ntawm cov khoom tseem ceeb - atorvastatin (los ntawm 25% mus rau 9%).

Txoj kab sib txuas ntawm qhov ntau npaum ntawm cov tshuaj thiab qhov degree ntawm nqus tau sau tseg.

Kev zom zaub mov

Kev noj zaubmov hauv lub siab yog ua rau lub siab ua haujlwm ntau nrog isoenzymes nrog kev tsim cov khoom noj ntawm lub cev.

Cov nyhuv inhibitory ntawm cov tshuaj Liptonorm yog kwv yees li 65-75% txiav txim los ntawm kev ua haujlwm ntawm cov cev hloov pauv thiab tuaj yeem ntev txog 30 teev.

Ib nrab-lub neej yog 15 teev. Nws yog tawm tom qab cov kab mob hepatic nrog bile, thiab tsawg dua 2% ntawm qhov kev lees txais yog txiav txim siab hauv zis.

Atorvastatin tsis tuaj yeem raug tshem tawm thaum lub sijhawm mob hemodialysis.

5. Txoj kev ntawm kev tswj hwm thiab kev noj tshuaj ntau npaum li cas

Ua ntej pib Liptonorm txoj kev kho, tus neeg mob raug pom zoo kom hloov mus rau cov khoom noj tshwj xeeb, uas ua kom cov ntshav lipids tsawg dua.

Cov tshuaj yuav tsum tau noj qhov ncauj ib hnub ib zaug, qhov yuav tsum tau ua yog siv rau tib lub sijhawm. Kev noj tsis cuam tshuam rau kev noj tshuaj.

Thawj koob tshuaj pom zoo ntawm kev kho mob yog 10 mg, tom ntej no cov tshuaj no raug xaiv nyob ntawm seb cov ntshav cov roj nyob hauv cov ntshav siab ntawm txhua tus neeg mob.

Vim tias kev tshem tawm qeeb ntawm atorvastatin los ntawm lub cev, Liptonorm yuav tsum siv kom zoo rau cov neeg mob uas lub siab tsis ua haujlwm.

Cov lus qhia rau kev siv Liptonorm, analogues thiab tshuaj xyuas

Txhawm rau tiv thaiv kev nce hauv cov roj (cholesterol), koj yuav tsum ua lub neej noj qab haus huv. Rau cov uas rau leej twg tiv thaiv yog tsis txaus, cov kws kho mob tsim cov tshuaj Liptonorm.

Nws yog ib feem ntawm pab pawg neeg ntawm statins uas ua rau muaj kev tsis haum tshuaj biochemical los ntawm kev ua kom tsis txhob muaj cov kab mob siab rau daim siab. Qhov no ua rau muaj kev txo qis hauv cov roj (cholesterol) hauv intracellular concentration thiab ua kom LDL receptors. Raws li qhov tshwm sim, qhov tawg ntawm "phem" cov roj (cholesterol) nrawm nrawm dua, tab sis tsis yog cuam tshuam rau "zoo".

Cov tshuaj raug muag los ntawm cov tshuaj, tus nqi ntawm Liptonorm sib txawv hauv qhov ntau ntawm 180-350 rubles. rau kev ntim khoom.

Liptonorm yog siv los kho:

Thawj hypercholesterolemia,
Hetero- thiab homozygous cov kab mob hypercholesterolemia (ua ke nrog kev noj haus)
Mixed hyperlipidemia.

Daim ntawv thov ua haujlwm

Cov lus qhia rau kev siv Liptonorm qhia tias ua ntej koj yuav tsum hloov mus rau kev noj zaub mov kom zoo. Nws lub hom phiaj yog los txo cov qib ntawm cov lipids hauv cov ntshav mus rau ib qib. Cov khoom noj yuav tsum tswj kom txog thaum ua tiav chav kho.

Cov tshuaj yuav tsum quag ib hnub ib zaug ntawm ib lub sijhawm, tsis hais noj zaub mov. Cov tshuaj rau lub caij pib yog 10 mg (noj ib zaug). Tom qab ntawd, yog tias tsim nyog, tus kws kho mob hloov kho qhov tshuaj txhua hnub, ntsuas LDL cov ntsiab lus hauv cov ntshav, tab sis qhov no tuaj yeem ua tsis pub dhau 1 zaug hauv 4 lub lis piam. Qhov siab tshaj plaws pub rau ib hnub twg yog 80 mg.

Cov lus qhia rau Liptonorm tseem qhia tau tias nrog lub siab ua haujlwm tsis zoo, ua rau cov tshuaj tsis tuaj yeem ua rau qis, yog li tus kws kho mob yuav tsum soj ntsuam cov kev ua haujlwm hauv lub nruab nrog cev.

Yog tias pom muaj cov kab mob hloov pauv hloov loj, qhov kev noj tshuaj yog txo sai lossis kev kho mob nres.

Kev Sib Sau thiab daim ntawv ntawm kev tso tawm

Liptonorm yog ib ntsiav tshuaj nrog lub khauj khaus ntawm 10 thiab 20 mg. Nyob rau hauv tsos lawv yog dawb, puag ncig thiab convex ntawm txhua sab.
Cov tshuaj muaj nqis yog atorvastatin. Ntu khoom siv yog calcium carbonate, Tween 80, hydroxypropyl cellulose, cellulose microcrystals, magnesium stearate, lactose, croscarmellose, titanium dioxide thiab polyethylene glycol.

Sab sij huam

Liptonorm cov chaw tsim tshuaj ntsuab ceeb toom tias qhov tsis txaus siab tsis zoo tuaj yeem cuam tshuam cov kabmob thiab cov tshuab sib txawv.

Cov nyom tiv thaiv cuam tshuam nrog cov khoom nruab nrog cev:

Pob ntseg hauv pob ntseg
Hemorrhage nyob rau hauv lub qhov muag,
Hloov pauv hauv saj (nce txog poob)
Mob caj pas
Mob taub hau
Qhov cuam tshuam ntawm kev pab,
Parosmia,
Qhuav ntawm lub qhov muag.

Kev phiv tshuaj los ntawm lub hauv nruab nrab hauv lub paj hlwb tsis tau txiav txim. Ntawm lawv yog:

Insomnia
Kev nkees nkees
Kev nco ploj
Paresthesia
Kev xav kev nyob tsis tus thiab kev nyuaj siab,
Ntxoov Huaj
Mob paj hlwb peripheral,
Lub ntsej muag tuag tes tuag taw
Hyperkinesis
Npau suav phem
Ataxia
Tsaus muag.

Qee cov neeg mob ntsib teeb meem ntawm lub siab thiab cov hlab ntsha. Lawv muaj cov tsos mob xws li:

Mob qab lub pob tw
Lub plawv dhia
Siab lossis qis siab,
Vasodilation
Phlebitis
Lus Aaskiv
Angina pectoris,
Arrhythmia.

Nws muaj kev pheej hmoo ntawm qhov tsis tuaj yeem tsim cov ntshav, uas ua rau:

Cov teeb meem hauv plab ua tau:

Xeev siab ntuav nrog ntuav
Cem quav lossis raws plab
Hepatic colic,
Mob plab thiab tsam plab
Tsis hnov qab
Glossitis
Cov pos hniav los ntshav
Lub Siab Mob Siab
Mob taub hau jaundice,
Stomatitis
Ntxoov ntxoo,
Kub siab thiab caws pliav
Lub cev qhuav, yaig, thiab qhov ncauj mob,
Kab mob siab
Mob plab zom mov
Duodenal mob rwj,
Kev mob caj dab
Dysphagia
Rectal los ntshav.

Qee zaus cov lus tsis zoo tshwm sim los ntawm tus kheej genitourinary kheej yog qee zaum pom:

Sab Nraud Nruab Nruab,
Jade
Mob Urogenital
Dysuria (suav nrog kev ceev thiab zis tsis ua),
Vaginal los ntshav
Tsis deev tsav,
Ejaculation ntshawv siab
Cuam meem txom.

Muaj peev xwm ua rau dermatological:

Dandruff thiab do hau,
Tawm hws
Eczema
Xeroderma,
Ecchymoses,
Petechiae.

Muaj kev phiv los sis cov leeg ua ke:

Mob caj dab
Rhabdomyolysis,
Myositis
Cramps
Neej Hmoob
Nqaij hypertonicity,
Myopathy
Tenosynovitis
Bursitis
Kev cog lus sib cog lus.

Muaj kev yws yws txog kev tsis haum tshuaj:

Cov tawv nqaij khaus
Cov tawv nqaij ua pob
Hu rau dermatitis,
Lub ntsej muag o
Urticaria
Quincke's edema thiab anaphylactic poob siab,
Photosensitization,
Lyell thiab Stevens-Johnson Syndromes
Exudative erythema multiforme.

Cov kev xav tsis zoo los cuam tshuam nrog lub ntsws ua pa:

Rhinitis
Mob ntsws ntsws
Bronchial hawb pob,
Mob ntsws o
Kab Ntsig
Dyspnoea

Muaj qhov ntxim nyiam ntawm kev tsim mastodynia, gynecomastia, exacerbation ntawm gout thiab hnyav ntxiv.

Tsawg dua 2% ntawm cov neeg mob, kuaj ntsuas hloov thiab raug kaw:

Alkaline phosphatase
Kom muaj ntshiab ALT thiab creatine phosphokinase,
Qib- thiab cov ntshav qog ntshav qab zib,
Albuminuria

Liptonorm: cov lus qhia rau kev siv, analogues, lus ceeb toom, tshuaj xyuas

Liptonorm yog cov tshuaj uas tau noj tshuaj rau cov ntshav siab ntau. Ua kom cov cholesterol ua rau ntau qhov tsis txaus siab, yog ib qho txaus ntshai tshaj plaws ntawm yog atherosclerosis.

Cov tshuaj yog rau statins, yog li cov kws kho mob tau sau ntawv nrog nws ceev faj heev. Ua ntej noj Liptonorm, tus neeg mob yuav tsum kawm cov lus qhia rau kev siv, nqi, kev txheeb xyuas.

(!) Cov tshuaj yuav tsum tsis meej pem nrog kev noj haus ntxiv Kablia VwjCov. Cov tshuaj noj thiab tshuaj noj ntxiv muaj ob qho sib txawv, tsis cuam tshuam lub ntsiab lus.

Muaj pes tsawg leeg thiab noj ntau npaum

Lub hauv paus tseem ceeb ntawm Liptonorm yog Atorvastatin calcium trihydrate rau hauv daim ntawv ntawm calcium ntsev. Ntawm nws cov ntu muaj xws li:

calcium carbonate
Ntxaib 80,
MCC
cov khoom noj khoom haus ntxiv E463 thiab E572,
croscarmellose sodium,
lactose
lim dej.

Liptonorm yog ua hauv ntsiav tshuaj daim ntawv. Coated ntsiav tshuaj ntawm 10 mg lossis 20 mg yog muaj nyob hauv qhov ntau ntawm 7, 10, 14, 20, 28 lossis 30 pcs.

Siv thaum cev xeeb tub

Cov yeeb tshuaj tseem ceeb yog txwv rau cov neeg mob thaum cev xeeb tub thiab thaum cev xeeb tub (pub niam mis) vim muaj qhov tsis zoo rau lub cev ntawm tus menyuam yug tshiab. Yog hais tias tus neeg mob tau npaj lub cev xeeb tub, nws zoo dua los tso nws rau ob peb lub hlis. Cov poj niam thaum kho mob Liptonorm yuav tsum tsis txhob saib tsis taus me nyuam.

Lwm txoj kev siv sib txuam nrog rau thaum yau thiab thaum tiav hluas. Cov ntaub ntawv hais txog kev kho mob ntawm cov menyuam yaus nrog rau cov tshuaj rau tam sim no tsis muaj.

Tus nqi tshuaj

Tus nqi ntawm cov tshuaj Liptonorm yog txiav txim siab los ntawm ntau cov qauv - tus naj npawb ntawm cov hlwv hauv pob, ntau npaum li cas, thiab lwm yam. Qhov nruab nrab, 10 ntsiav tshuaj mg tuaj yeem yuav hauv chaw muag tshuaj rau 200-250 rubles. Tus nqi ntawm ib pob ntawm 28 pcs. 20 mg txhua yog 400-500 rubles.

Hauv Ukraine, tus nqi ntawm ib cov tshuaj hauv qhov ntau npaum ntawm 20 mg yog 250-400 UAH.

Cov Lus Cim Liptonorm

Txawm hais tias Liptonorm yog ib hom tshuaj uas ua tau zoo heev, nws yuav tsis haum rau txhua tus neeg mob. Hypersensitivity rau ib qho kev sib xyaw ntawm cov tshuaj thiab overpriced yog ob qho laj thawj rau kev hloov nws nrog cov roj hmab pheej yig dua.

Cov tshuaj hauv qab no yog nyob ntawm cov analogues ntawm Liptonorm:

Atorvastatin
Atorvastatin-Teva,
Torvacard
Liprimar
Atoris
Vazator.

Kev Siv Tshuaj Xyuas

Kev tshuaj xyuas ntawm nws txoj kev siv qhia tau hais tias cov kws kho mob feem ntau muab tshuaj rau tus neeg mob yam tsis muaj cov ntsiab lus piav qhia txog cov yam ntxwv ntawm nws txoj kev tswj hwm thiab cov kev mob tshwm sim.

Tamara, Moscow: “Thawj thawj hnub tom qab noj tshuaj, Kuv pib mob hauv kuv lub plab, tom qab ntawd tso rau hauv kuv lub plab, thiab ob peb hnub tom qab - xeev siab thiab ntuav. Kuv tsis nyob rau hauv txhua txoj kev koom cov kev ua no nrog kev noj Liptonorm.

Txij li thaum kuv tau raug kev txom nyem los ntawm kev mob ntawm txoj hnyuv txij li thaum yau nrog kev hloov me me hauv kuv cov zaub mov, Kuv tam sim tig mus rau tus kws kho mob plab. Ua tsaug rau tus kws kho mob, Kuv pom tau hais tias dab tsi ua rau muaj kev tsis xis nyob hauv plab, tab sis kuv tseem mob siab txog cov lus nug.

Vim li cas kuv cov neeg noj zaub mov tsis ceeb toom kuv txog qhov yuav tshwm sim? ”

Ekaterina, Novosibirsk: "Kuv lub cev hnyav dhau los nrog kuv txij thaum kuv tus tub ntxhais hluas lub xyoo, tab sis tsuas yog thaum muaj hnub nyoog 30 xyoo kuv txiav txim siab saib xyuas kuv tus kheej thiab pom qhov ua rau kuv qhov teeb meem. Kev tshawb nrhiav hauv tsev sim pom tau hais tias qhov ua rau yog muaj cov roj (cholesterol) thiab cov kws qhia zaub mov noj kom kuv Liptonorm.

Thawj hnub, kuv cov ntshav siab tau nce mus rau 150. Hnub tom qab thaum sawv ntxov lub siab yog qhov tsis raug, tab sis tom qab noj su nws dhia ntxiv rau 160. Tom qab ntawd kuv txiav txim siab rov nyeem cov lus qhia thiab thaum kawg kuv nkag siab tias muaj xwm txheej dab tsi. Kuv cov ntshav siab yog qhov tshwm sim ntawm cov tshuaj.

Lub siab nres cia li nce tsuas yog 5 hnub tom qab pib kev kho mob. "

Kev nthuav qhia tag nrho cov kev txheeb xyuas saum toj no txog kev siv Liptonorm ntsiav tshuaj, nws yuav tsum txiav txim siab tias nws yog qhov yuav tsum tau sab laj tus kws kho mob ua ntej siv.

Firstly, qhov no yog vim qhov tseeb hais tias cov tshuaj muaj npe rau cov pab pawg ntawm cov statins uas tuaj yeem tiv thaiv qhov nce hauv cov cholesterol.

Raws li koj paub, kev teem sijhawm lossis tshem tawm qee tus neeg sawv cev cev xeeb tub tsuas tuaj yeem nqa los ntawm tus kws tshaj lij xwb.

Thib ob, cov tshuaj muaj ntau yam kev tiv thaiv thiab kev phiv los ntawm txoj hnyuv hauv plab, lub hauv plab mob hlwb, lub plawv thiab lwm cov kab ke tseem ceeb. Tus kws kho mob tshwj xeeb yuav tsum sau daim ntawv tshuaj noj, piav qhia txhua yam hauv daim ntawv thov, thiab qhia tus neeg mob txog kev muaj teeb meem.

Liptonorm: tus nqi ntawm cov tshuaj hauv cov khw muag tshuaj, cim thiab tshuaj xyuas

Liptonorm (liptonorm) - cov tshuaj los ntawm pab pawg ntawm statins, nws yog siv los txo cov roj hauv cov ntshav. Cov tshuaj ua haujlwm tsis huv ntawm cov tshuaj inhibit zus tau cov isoprenoids, pab txhawb kev nthuav cov hlab ntsha tuaj.

Cov tshuaj txo qis triglycerides, cov roj-tsawg cov roj cholesterol, nce cov ntsiab lus ntawm cov roj-zoo li cov roj ntsha, polypoprotein A. Feem ntau, cov kab mob ntshav qab zib yuav hnov cov nyhuv ntawm cov tshuaj 14 hnub tom qab pib kho, 4 lub lis piam yuav tsum dhau rau cov txiaj ntsig siab tshaj plaws.

Cov tshuaj tsis raug rau daim siab hnyav thiab mob plab hnyuv, ua kom tawm hauv lub cev nrog rau cov kua tsib. Ib nrab-lub neej yog 14 teev. Vim tias lub cev ua kom nquag plias ntawm lub cev ua haujlwm, cov nyhuv inhibitory kav ntev li 20 mus rau 30 teev. Thaum mob hemodialysis, cov tshuaj tsis txhaws tawm, tsawg dua 2% ntawm qhov tshuaj tau lees yog kuaj pom hauv cov zis.

Cov lus qhia rau kev siv yog sib xyaw hyperlipidemia, thawj hypercholesterolemia, heterozygous thiab homozygous tsev neeg hypercholesterolemia.

Tus nqi ntawm cov tshuaj Liptonorm hauv cov khw muag tshuaj yog 190 rubles, koj tuaj yeem yuav nws yam tsis muaj daim ntawv qhia los ntawm kws kho mob.

Cov lus qhia rau kev siv tshuaj

Ua ntej sau ntawv yuav tshuaj, nws raug nquahu kom hloov mus rau qhov kev noj zaub mov kom tsim nyog uas muab cov roj cholesterol hauv cov ntshav qis. Cov pluas noj yuas ua kom tag nrho lub sijhawm ntawm kev kho mob.

Daim ntawv thov kev qhia pom zoo kom haus 1 lub tshuaj ntawm cov tshuaj ib hnub, lub sijhawm noj mov tsis ua lub luag haujlwm, tab sis cov tshuaj yuav tsum tau noj nyob rau tib lub sijhawm. Kev muab tshuaj rau tus mob ntshav qab zib yog 10 mg ntawm cov tshuaj, yav tom ntej noj cov tshuaj zoo yog xaiv ib tus zuj zus.

Qhov ntau npaum ntawm qhov ntau npaum li cas yog nyob ntawm qib uas cov roj (cholesterol) tsawg dua, qhov hnyav ntawm cov txheej txheem pathological, qhov kev ua tau zoo ntawm kev kho mob feem ntau. Koob tshuaj hloov tau yog tsawg kawg 4 lub lis piam tom qab.

Qhov siab tshaj plaws ntawm 80 mg ntawm cov tshuaj tuaj yeem noj ib hnub.

Analogues ntawm cov tshuaj

Yog tias Liptonorm tsis haum rau ib qho laj thawj, tus kws kho mob tau sau tshuaj analogues. Cov neeg nyiam tshaj plaws los ua: Aterocardium, Lipona, Torvakard, Atorvastatin, Anvistat, Atomaks, Liprimar.

Tus nqi ntawm cov tshuaj nyob ntawm qhov chaw tsim tshuaj paus, rau Liptonorm ntsiav tshuaj tus nqi yog pheej yig heev.

Cov ntaub ntawv hais txog statins yog muab hauv video hauv tsab xov xwm no.

Qhia koj qab zib lossis xaiv tus tub los ntxhais rau cov lus pom zoo. Nrhiav tsis pom. Nrhiav. Nrhiav tsis pom. Pom. Nrhiav tsis pom.

Kev tshuaj xyuas ntawm cov kws kho mob hais txog liponorm

Ntsuam xyuas 2.9 / 5

Txij nkawm

Nqe / zoo

Sab sij huam

Cov tshuaj "Liptonorm" sawv ntawm caj npab zoo los ntawm cov kws kho mob ntawm neurologist thiab gastroenterologist.

Tus nqi kuj tuaj yeem qis dua. Ib qho tshuaj zoo yuav tsum tsim nyog pheej yig dua.

Raws li txoj cai, nws yog tshuaj rau cov neeg mob uas muaj cov roj cholesterol siab hauv kev tshuaj ntsuam. Saib xyuas thiab kho ntxiv cov tshuaj no. Nws qhia tau nws tus kheej zoo hauv kev siv tshuaj.

Nrog lub siab ua haujlwm tsis zoo

Cov tshuaj yog sau ntawv nrog ceev faj nyob rau hauv lub xub ntiag ntawm keeb kwm ntawm kab mob siab.

Liptonorm yog contraindicated nyob rau hauv cov mob hauv qab no:

nquag ua haujlwm ntawm daim siab mob (piv txwv li, nrog kev muaj mob rau daim siab ntev, mob siab voos mob ntshav siab),
nce kev ua si ntawm hepatic transaminases (tshaj li qhov txwv sab sauv ntawm qhov nruab nrab los ntawm tsawg kawg 3 zaug piv nrog VGN) ntawm kev tsis paub txog tus mob,
cirrhosis ntawm daim siab ntawm ntau yam etiologies,
daim siab ua rau lub siab (Cov Me Nyuam-Pugh chav A thiab B).

Tus nqi ntawm Liptonorm hauv chaw muag tshuaj

Tus nqi ntim ntawm Liptonorm 10 mg ntawm 28 ntsiav tshuaj yog kwv yees li 200 rubles, qhov ntim khoom ntawm 28 ntsiav tshuaj Liptonorm 20 mg yog kwv yees li 390 rubles.

Kev Kawm Ntawv: Thawj Moscow State Medical University muaj npe tom qab I.M. Sechenov, tshwj xeeb "Tshuaj General".

Cov ntaub ntawv hais txog cov tshuaj raug muab dav dav, muab rau kev qhia tawm thiab tsis hloov chaw cov lus qhia. Kev siv tshuaj rau tus kheej yog qhov txaus ntshai rau kev noj qab haus huv!

Yog tias koj lub siab ua haujlwm, kev tuag yuav tshwm sim hauv ib hnub.

Cov poj niam feem ntau muaj peev xwm tau txais kev lom zem ntau dua los ntawm kev xav txog lawv lub cev zoo nkauj hauv daim iav dua li ntawm kev sib deev. Yog li, cov poj niam, siv zog ua kom muaj kev sib haum xeeb.

Thaum lub sijhawm ua haujlwm, peb lub hlwb siv ntau npaum li cas ntawm lub zog sib npaug rau 10-watt lub teeb lub teeb. Yog li cov duab ntawm lub teeb txawb saum koj lub taub hau thaum lub sijhawm pom ntawm qhov kev xav zoo nkauj tsis yog deb ntawm qhov tseeb.

Raws li kev tshawb fawb, cov poj niam uas haus ob peb khob npias lossis cawv txiv hmab ib lim tiam muaj feem ntau yuav muaj mob khees xaws mis.

Tus neeg noj tshuaj tiv thaiv kab mob feem ntau yuav rov qab muaj kev nyuaj siab. Yog tias ib tug neeg mob nrog kev nyuaj siab ntawm nws tus kheej, nws muaj txhua lub sijhawm tsis nco qab txog lub xeev no tas mus li.

Qhov kub siab tshaj plaws ntawm lub cev tau sau cia ntawm Willie Jones (USA), uas tau nkag rau hauv tsev kho mob nrog qhov kub txog 46,5 ° C.

Yog tias koj luag nyav tsuas yog ob zaug ib hnub, koj tuaj yeem txo cov ntshav siab thiab txo qhov kev pheej hmoo ntawm lub plawv thiab mob nkees.

Nrog kev mus saib xyuas lub txaj tanning, txoj kev pheej hmoo ntawm kev mob qog tawv nqaij yuav nce 60%.

Cov tib neeg uas tau noj tshais ua ntu zus feem ntau yog cov muaj rog.

Tib neeg lub plab ua haujlwm tau zoo nrog cov khoom txawv teb chaws thiab tsis muaj kev cuam tshuam kho mob. Gastric kua txiv yog paub tias yuav yaj txawm npib.

Lub siab yog qhov ua haujlwm hnyav tshaj plaws hauv peb lub cev. Nws qhov hnyav nruab nrab yog 1.5 kg.

Qhov hnyav ntawm tib neeg lub hlwb yog li 2% ntawm tag nrho lub cev qhov hnyav, tab sis nws noj txog 20% ntawm cov pa mus rau hauv cov ntshav. Qhov tseeb no ua rau tib neeg lub hlwb muaj kev tiv thaiv rau kev puas tsuaj los ntawm cov pa oxygen.

Qhov ua kom pom kev vibrator ua ntej nyob rau xyoo 19th. Nws ua haujlwm ntawm lub tshuab tso hluav taws xob thiab nws tau npaj kho qhov mob poj niam.

Qhov nruab nrab lub neej ntawm cov laug yog tsawg dua ntawm txoj cai.

Ntau cov tshuaj tau xub pib ua lag luam li tshuaj. Piv txwv li yeeb dawb, tau pib ua lag luam ua tshuaj hnoos. Thiab cocaine tau pom zoo los ntawm cov kws kho mob ua tshuaj loog thiab yog lub zog ntawm kev ua kom lub siab ntev.

Txhua tus tuaj yeem ntsib cov xwm txheej uas nws plam hniav. Nov yog txheej txheem ib txwm ua los ntawm kws kho hniav, los yog ua rau raug mob. Hauv txhua thiab.

Kev txheeb xyuas ntawm cov neeg mob txog mob liponorm

Nrog rau hyperlipidemia sib xyaw, tus kws kho mob tau sau ntawv rau kuv cov tshuaj "Liptonorm." Nws hais tias muaj cov kev tshuaj xyuas zoo ntawm Liptonorm cov tshuaj los ntawm cov kws kho mob thiab cov neeg mob. Zoo, Kuv tsis xav, yog tias tsuas yog nws yuav pab. Kuv noj "Liptonorm" raws li cov lus qhia, ib ntsiav tshuaj ib hnub. Kom txog rau thaum cov koob tau nce siab, qhov no yuav tsum txaus.

Kuv pheej raug kev sim siab kom ntshav siab thiab mob hauv kuv lub siab. Kuv tig mus rau tus kws kho mob hlwb, nws yog tsev neeg nrog peb, thiab kuv niam tseem raug kho los ntawm tus kws kho mob no. Tus kws kho mob tau qhia tias yuav tsum mus kuaj mob thiab dhau ntawm txhua qhov kev xeem. Nws tau muab tawm hauv kuv cov ntshav feem pua ntawm cov roj (cholesterol) tau nce thiab kuv tau maj nrawm xav txo nws. Nws yog lub sijhawm no tus kws kho mob tau sau ntawv rau kuv Liptonorm. Kuv coj nws ib hnub ib zaug ntawm 10 mg. Noj "Liptonorm" koj yuav tsum ua raws li kev noj haus. Tsis txhob noj cov roj thiab kib, tsis meej tso tseg butter thiab cov nqaij npuas roj tsev. Tom qab ob lub lim tiam, cov cholesterol pib poob qis zuj zus, thiab tom qab lwm peb lub lis piam nws rov qab los nyob li qub. Tam sim no kuv mloog zoo li qub, tab sis kuv ua raws li kuv kev noj haus.

Kuv txiv tau raug tsim tawm ib zaug liptonorm tiv thaiv cov roj cholesterol siab. Raws li kev soj ntsuam, Kuv nco ntsoov tias tsawg kawg peb zaug hauv ib hnub coj nws, rau ib chav kawm tag nrho nws tsis muaj dab tsi tsis muaj kev noj haus tshwj xeeb. Nws kuj yog qhov zoo rau tag nrho cov cawv nrog rau thaum haus cawv ntawm liponorm, uas yog, txawm tias nyob rau hnub so, tsis txhob cia koj tus kheej tso dej cawv (thiab ua kom cov txiaj ntsig, tsis kam mus ib txhis), txwv tsis pub yuav muaj teeb meem rau lub plawv, raum, kab mob ntsws. Feem ntau, kuv yuav tsis hais tias qhov no yog cov tshuaj zoo heev: leej twg muaj roj cholesterol yob dua, nws zoo dua tsis noj tshuaj, tab sis kev txhaj tshuaj nrog lub zog zoo.

Cov lus qhia luv luv

Liptonorm (cov tshuaj nquag yog atorvastatin) yog ib qho tshuaj lipid-txo cov tshuaj uas yog pawg ntawm HMG-CoA reductase inhibitors (hauv lwm yam lus, rau statins). Kev txhawb nqa ntawm cov kev ua ntawm cov neeg tau hais tseg tuaj yeem ua rau cov kev hloov pauv biochemical ua tiav, qhov txiaj ntsig ntawm qhov no yog qhov kev txo qis ntawm cov concentration ntawm cov roj (cholesterol) hauv cov hlwb thiab kev ua haujlwm ntawm LDL receptors, uas ua rau muaj kev cuam tshuam ntawm kev rhuav tshem cov roj "phem" (LDL). Cov nyhuv hypolipidemic ntawm liptonorm yog vim qhov txo qis hauv cov roj (cholesterol) tag nrho, tab sis tshwj xeeb vim yog LDL thiab tsis ua rau cov roj "zoo" (HDL). Qhov "kev nruab nrab" ntawm LDL yog qhov koob tshuaj-siv, uas yog, ntau dua qhov nws yog, qhov ntau dua koob tshuaj liponorm (ib txwm muaj, nyob rau hauv txoj haujlwm kho). Nws yuav tsum raug sau tseg tias 70% ntawm lipid-txo cov nyhuv yog muab los ntawm cov nquag metabolites ntawm cov tshuaj. Cov nyhuv ntawm statins rau qib triglyceride tsis yog qhov txiav txim siab, vim hais tias cov tshuaj no tsis hloov pauv kev ua haujlwm ntawm lipoprotein thiab hepatic lipases, tsis ua lub luag haujlwm ntawm kev txiav txim siab lipogenesis thiab catabolism ntawm cov roj ntsha dawb. Txawm li cas los xij, txo qis hauv qib ntawm LDL nyob rau hauv cov tshuaj, ib txoj kev los sis lwm qhov, cuam tshuam triglycerides. Liptonorm muaj txiaj ntsig tsis yog rau nws cov txiaj ntsig hypolipidemic: zoo li lwm yam statins, nws muaj txiaj ntsig zoo ntawm endothelium, inhibiting kev txhim kho ntawm endothelial kawg (lub forerunner ntawm atherosclerosis), ntawm phab ntsa ntawm cov hlab ntshav, txhim kho rheology, thiab muaj cov antioxidant thiab antiproliferative effect. Cov tshuaj cuam tshuam sai sai los ntawm txoj hnyuv hauv lub plab. Nws muaj lub cev nqus tau qis qis, uas yog vim muaj lub zog presystemic hauv lub siab. Ib nrab-lub neej ntawm liporm yog qhov nruab nrab li ntawm 14 teev. Cov tshuaj tau tawm hauv lub cev nrog rau cov kua tsib. Liptonorm muaj nyob hauv daim ntawv foos. Pharmacotherapy yog ua tiav los ntawm keeb kwm ntawm kev coj noj coj ua "antihypercholesterolemic" nyob rau hauv cov xwm txheej zoo li no. Cov koob tshuaj tau teeb tsa ib tus kheej hauv txhua kis thiab nyob ntawm thawj theem ntawm cov roj (cholesterol). Qhov "pib" koob tshuaj ntawm cov tshuaj raws li cov lus pom zoo dav dav yog 10 mg 1 zaug nyob rau ib hnub.

Cov txiaj ntsig kho tau tshwm sim nyob rau lub lim tiam thib peb txij li kev pib ua haujlwm, thiab lub siab tshaj plaws ntawm kev ua ntawm liptonorm yog pom tom qab ib hlis ntawm cov tshuaj pharmacological tsis tu ncua. Yog tias qhov xwm txheej xav tau nws, qhov koob tshuaj yuav raug maj mam nce mus rau qhov ntau tshaj plaws txhua hnub ntawm 80 mg, thaum lub sijhawm nruab nrab ntawm qhov nce ntxiv yuav tsum yog tsawg kawg 4 lub lis piam. Ua ntej thiab thaum kho, nws yog ib qhov tsim nyog los saib xyuas txhua tus tseem ceeb tshaj plaws ntawm daim siab ua haujlwm - lub npe "Kev kuaj mob siab." Kev nce qib ntawm aminotransferases tawm tsis muaj kev xaiv tab sis yuav soj ntsuam qhov kev ua haujlwm ntawm cov enzymes kom txog rau thaum ua tiav rov qab mus rau qub. Thaum tswj hwm kom muaj peb zaug kev ua haujlwm ntawm AST lossis ALT, kev hloov kho koob tshuaj liponorm lossis tshem tawm tag nrho cov tshuaj pom zoo. Cov tsos ntawm cov cim ntawm myopathy thaum kho mob qhia tau hais tias yuav tsum txiav txim siab qhov kev ua ntawm creatine phosphokinase. Thaum tswj hwm qhov theem nce siab ntawm qhov enzyme no, qhov kev txo qis ntawm cov tshuaj liponorm lossis kev txiav tawm ntawm chav kawm tshuaj tau qhia. Txoj kev pheej hmoo ntawm myopathy thaum noj liptonorm nce nrog kev sib txuam ntawm cov tom kawg nrog antifungal azoles, niacin, erythromycin, cyclosporine. Lub sijhawm nyob hauv tus neeg mob cov keeb kwm ntawm kev haus cawv ntev ua rau lub luag haujlwm ntxiv rau tus kws kho mob, zoo li Hauv qhov no, kev kho mob nrog liptonorm yuav tsum tau ua nrog ceev faj heev.

Hauv kev xaus, xav paub cov ntaub ntawv yuav tsum tau muab uas yuav tsum txaus siab tag nrho cov neeg nyeem. Cov kws tshawb fawb hauv Lavxias tau ua qhov kev sib piv ntawm kev ua tau zoo thiab kev nyab xeeb ntawm liptonorm nrog thawj cov tshuaj atorvastatin - lyprimar los ntawm lub tuam txhab tshuaj Pfizer. Qhov tseeb yog tias kev sib cav mus ib txhis ntawm cov generics thiab cov tshuaj qub tau pib txij li lub sijhawm immemorial, tsiv cov kws tshawb fawb mus rau ntau dua thiab cov kev tshawb fawb tshiab hauv thaj chaw no. Hauv qhov teeb meem tshwj xeeb no, liptonorm qhia nws tus kheej los ntawm sab heev, qhia kev ua haujlwm hypocholesterolemic piv rau lypimar thiab tsuas yog me ntsis yielding rau nws nyob rau hauv cov nqe lus ntawm kev nyab xeeb.

Kws Tshuaj

Hypolipidemic tus neeg sawv cev los ntawm pawg statins. Raws li lub hauv paus ntsiab lus ntawm kev sib tw kev sib tua, cov qauv hluav taws xob (statin molecule) khi rau qhov ntawd ntawm coenzyme A receptor qhov twg HMG-CoA reductase txuas nrog. Lwm feem ntawm statin lwg me me tiv thaiv kev hloov pauv ntawm hydroxymethylglutarate rau mevalonate, ib qho nruab nrab hauv cov hluavtaws sib xyaw ua ke ntawm cov roj (molecules) roj. Kev txwv tsis pub muaj kev ua haujlwm ntawm HMG-CoA reductase ua rau muaj cov kev hloov tshwm sim ntxiv, ua rau muaj qhov txo qis ntawm cov roj uas txhaws txaus thiab muaj kev cuam tshuam hauv kev ua haujlwm ntawm LDL receptors thiab, raws li, kev nrawm catabolism ntawm LDL cov roj (Xc).

Cov nyhuv hypolipidemic ntawm statins yog txuam nrog qhov kev txo qis ntawm tag nrho cov cholesterol vim LDL cov cholesterol. Qhov txo qis hauv LDL yog koob tshuaj-siv thiab tsis yog linear, tab sis exponential. Cov nyhuv inhibitory ntawm atorvastatin tiv thaiv HMG-CoA reductase yog kwv yees li 70% txiav txim los ntawm qhov kev ua haujlwm ntawm nws cov circulating metabolites.

Statins tsis cuam tshuam rau kev ua haujlwm ntawm lipoprotein thiab hepatic lipases, tsis txhob cuam tshuam loj heev ntawm kev sib txuas thiab catabolism ntawm cov roj ntsha dawb, yog li ntawd, lawv cov txiaj ntsig ntawm theem TG yog theem nrab thiab tsis ncaj los ntawm lawv cov kev cuam tshuam tseem ceeb los txo qis LDL-C. Kev poob qis hauv theem ntawm TG thaum kho nrog statins pom meej cuam tshuam nrog kev qhia ntawm cov seem (apo E) receptors nyob rau saum npoo ntawm hepatocytes koom nrog catabolism ntawm STD, uas muaj li 30% TG. Piv nrog rau lwm cov statins (tshwj tsis yog rosuvastatin), atorvastatin ua rau muaj ntau dua qhov tseeb hauv qib TG.

Ntxiv rau qhov teebmeem lipid-txo qis, statins muaj cov txiaj ntsig zoo ntawm endothelial kawg (preclinical kos npe ntawm thaum ntxov atherosclerosis), nyob rau ntawm phab ntsa vascular, atheroma lub xeev, txhim kho rheological ntshav, muaj antioxidant, antiproliferative zog.

Atorvastatin txo qis cov roj cholesterol hauv cov neeg mob homozygous tsev neeg hypercholesterolemia, uas feem ntau tsis teb rau kev kho nrog lipid-txo tshuaj.

Cov Tshuaj Pharmacokinetics

Atorvastatin txau siab heev los ntawm kev mob hnyuv. Kev tsis txaus ntseeg lub cev muaj peev xwm qis qis - txog 12%, uas yog vim yog lub teeb meem (presystemic clearance) hauv lub plab zom mov thiab / lossis vim "thawj hla" los ntawm lub siab, feem ntau nyob ntawm thaj chaw ua.

Atorvastatin yog metabolized nrog kev koom tes ntawm CYP3A4 isoenzyme nrog kev tsim ntawm ntau cov tshuaj uas yog cov tshuaj tiv thaiv ntawm HMG-CoA reductase.

T_1/2 los ntawm ntshav ntshav yog li 14 teev, txawm hais tias T_1/2 qhov inhibitor ntawm kev ua haujlwm ntawm HMG-CoA reductase yog kwv yees li 20-30 teev, uas yog vim muaj kev koom tes ntawm cov metabolites nquag.

Plasma protein khi yog 98%.

Atorvastatin raug tawm hauv daim ntawv ntawm metabolites feem ntau nrog cov kua tsib.

Cev xeeb tub thiab lactation

Cov tshuaj yog contraindicated nyob rau hauv cev xeeb tub thiab lactation (pub niam mis).

Kev siv Liptonorm tsis pom zoo hauv poj niam kev yug menyuam lub hnub nyoogtsis siv txoj hauv kev tiv thaiv kom muaj txiaj ntsig. Liptonorm yuav tsum tau tsum tsis ua hauj lwm ib hlis ib zaug ua ntej kev xeeb tub.

Cov lus thiab cov xwm txheej ntawm kev cia

Liptonorm tuaj yeem siv 24 lub hlis txij li hnub ntawm kev tsim khoom, raug rau kev ua haujlwm cia. Txhawm rau ua qhov no, nws tau muab tso rau hauv qhov chaw tsaus, qhuav thiab siv tsis tau rau cov menyuam yaus uas muaj qhov kub thiab txias tsis pub dhau 25 ° C.

Tus nqi ntawm lub cuab yeej yog nyob ntawm txoj cai nqe ntawm lub tsev muag tshuaj thiab qhov nruab nrab yog 238 rubles.

Yog tias tsim nyog, cov tshuaj raug hloov nrog cov tshuaj zoo sib xws:

Lipoford
Atom
Vazator,
Thorvakard
Atorvastatin,
Tub los ntxhais,
Atocord.

Tus kws kho mob xaiv cov nyiaj. Txhawm rau tsis txhob ua rau lub xeev ntawm kev noj qab haus huv, nws tsis pom zoo kom hloov nws tus kheej ntawm txoj kev kho mob.

Stanislav, 53 xyoo, Yaroslavl: “Qhov teeb meem nrog cov hlab plawv plawv ua rau xav tau kev kho mob nyuaj. Lub sijhawm tiv thaiv yog kwv yees li ib hlis. Muaj ntau yam tshwm sim, tab sis kuv tsis xav ntawm kuv tus kheej. Cov tshuaj yog pheej yig, thiab nws cov hauj lwm zoo tuaj yeem pom tom qab ob peb hnub ntawm kev txais neeg mob. "

Liptonorm - ib qho tshuaj lipid-txo cov tshuaj zoo

Zhuravlev Nikolay Yuryevich

Liptonorm yog ib qho ntawm lipid-txo cov tshuaj ntawm statin pawg. Lub hauv paus ua haujlwm tseem ceeb yog atorvastatin tivthaiv, cov nyhuv ntawm uas yog los inhibit qhov kev ua ntawm reductase.