Cov lus qhia rau kev siv tshuaj, tshuaj yeeb dawb, tshuaj xyuas
Nws siv los kho txhua hom mob ntshav qab zib. Muab rau cov poj niam cev xeeb tub, yog tias kev noj zaub mov noj tsis muaj txiaj ntsig, nrog rau tom qab yug menyuam tas. Recombinant tib neeg lub cev insulin kuj tseem muaj txiaj ntsig hauv kev khiav haujlwm, raug mob, kis kab mob, uas nrog kub cev.
Tsuas yog tus kws kho mob tuaj yeem sau ntawv qhov ntau npaum li cas thiab cov txheej txheem ntawm kev tswj hwm tshuaj, txij li txhua kis nws txhua tus nyob ntawm tus kheej qhov yam ntxwv ntawm chav kawm ntawm tus kab mob.
Feem ntau, ib qho kev txhaj tshuaj tau ua tiav subcutaneously, 15-30 feeb ua ntej noj mov. Koj tuaj yeem nkag rau hauv qhov quav thiab intramuscularly. Tus txheej txheem naj npawb ntawm kev txhaj tshuaj yog 3 zaug hauv ib hnub. Tam sim ua ntej txhaj, koj yuav tsum paub tseeb tias lub raj mis nrog cov tshuaj nyob ntawm qhov sov li chav nyob, thiab cov kua hauv nws yog dawb los ntawm impurities. Kev siv cov tshuaj nrog txhua yam ntawm opacities tsis tuaj yeem lees txais.
Qhov kev hloov kho ntawm cov kua dej ntawm cov kua dej yog ua tiav thaum muaj kev ua txhaum ntawm tib neeg lub cev, yog kuaj tau:
- kis kab mob
- cov thyroid teeb meem
- Addison's disease
- Kev Ua Siab Ncaj
- mob ntshav qab zib hauv cov neeg muaj hnub nyoog 65 xyoos.
Cov piam thaj hauv qab yuav poob qis rau cov laj thawj hauv qab no:
- hloov chaw txhaj tshuaj,
- noj tshuaj ntau dhau
- kev siv lub cev
- muaj teeb meem nrog txoj hnyuv plab hnyuv
- cov tshuaj tiv thaiv rau kev siv ua ke ntawm lwm yam tshuaj,
- thaum hloov pauv tus neeg mob mus rau tib neeg cov kua dej.
Rov qab rau cov lus txheej txheem
Kuv nyiam (los ntawm Latin cov lus - insulin hauv kev daws teeb meem) muaj npe lag luam sib txawv. Nws nyob ntawm lub sijhawm ntawm cov tshuaj thiab cov txheej txheem tsim khoom. Txais tib neeg cov tshuaj insulin tshwm sim artificially, siv kev tsim tshuaj engineering. Qhov zoo tshaj yuav txiav txim siab nws lub sijhawm. Kuj tseem muaj cov tshuaj yeeb tshuaj - ob-theem insulin, nrog lub sijhawm sib txawv ntawm kev ua kom pom. Cov tshuaj hauv qab no yog cais tshwj xeeb:
Ntev ntawm kis kab mob Ntsej muag ntawm qhov tshwm sim Txheem raug piv txwv ntawm cov tshuaj tiv thaiv luv luv Ua yeeb yaj kiab Cov tsos mob thawj zaug tshwm sim tom qab 30 feeb tom qab kev tswj hwm ntawm Humulin, Rinsulin, Gansulin Lub cev nquag pib pib hauv 2-3 teev, Insuran Bioinsulin Nruab Nrab Cov kev ua yeeb yam Cov cim tau pib ua ntej 1 teev, muaj kev tawm dag zog - tom qab 6-7 teev "Boisulin" "Protafan" Tom qab 12 teev, "Insuman" raug tshem tawm ntawm lub cev tag nrho. Muaj peev xwm hloov qhov kev ncua ntev ntawm lub cev ntawm "Gansulin" "Gensulin" Txais tos yog cuam tshuam ncaj qha rau kev siv khoom noj "Mikstard" Thov 2 zaug ib hnub, 30 feeb ua ntej noj mov Rov qab los rau saum lub rooj
Txo cov ntshav qabzib, txo lub cev tsis haum yog qhov tsuas yog contraindications rau kev siv cov tshuaj insulin. Cov kev mob tshwm sim yog kev ua xua, nyob rau hauv daim ntawv ntawm urticaria, hypoglycemia. Koj tuaj yeem soj ntsuam tau:
- hypoglycemic coma,
- kev cuam tshuam ntawm cov hlab ntsha hlab ntsha thiab hlab ntsha,
- muaj teeb meem nrog kev hais lus thiab lub zeem muag,
- tsis meej pem,
- hyperglycemia
- o ntawm thaj chaw txhaj tshuaj.
Rov qab rau cov lus txheej txheem
Tib neeg insulin (kev tshuaj ntsuam genetic engineering) tsis sib xws nrog lwm yam tshuaj. Sulfanilamide thiab tshuaj tua kab mob, nrog rau cov tshuaj tetracyclines, theophylline, quinidine, quinine, ethanol, txo cov concentration ntawm cov piam thaj hauv cov ntshav. Ntawm qhov tsis sib xws, nws cov ntsiab lus muaj ntau ntxiv: diuretics, cov thyroid hormones, tshuaj tiv thaiv kab mob, tshuaj maj, nicotine, epinephrine, qhov ncauj tiv thaiv.
Zaj dab neeg ntawm ib qho ntawm peb cov neeg nyeem, Inga Eremina:
Kuv qhov hnyav tau tshwj xeeb tshaj yog kev nyuab siab, Kuv hnyav ib yam li 3 tus lej wrestlers ua ke, uas yog 92kg.
Yuav ua li cas tshem tawm qhov hnyav tshaj kom tiav? Yuav daws cov tshuaj hormonal hloov thiab rog dhau li cas? Tab sis tsis muaj dab tsi yog li disfiguring lossis hluas rau ib tus neeg li nws daim duab.
Tab sis yuav ua li cas thiaj poob ceeb thawj? Laser liposuction phais? Kuv pom - tsawg kawg 5 txhiab daus las. Cov txheej txheem kho vajtse - LPG zaws, cavitation, RF nqa, myostimulation? Ib nyuag pheej yig dua - cov nqi kawm ntawm 80 txhiab rubles nrog kws tshaj lij kws paub txog khoom noj khoom haus. Koj muaj peev xwm tiv thaiv sim khiav ntawm lub cos, mus rau qhov tsis pom kev.
Thiab thaum twg kom nrhiav tau txhua lub sijhawm no? Yog thiab tseem kim heev. Tshwj xeeb tam sim no. Yog li ntawd, rau kuv tus kheej, Kuv xaiv txoj kev sib txawv.
Thaum noj tshuaj ntau dhau, tus neeg hnov yuav tshaib plab, mob taub hau, tshee tshee, ntshav ntog poob qis. Tus neeg mob yog zoo li yog nyob hauv lub xeev pw tsaug zog. Thaum pib theem pib ntawm tus mob, ib tug neeg tau tshem ntawm cov tsos mob no ntawm nws tus kheej. Nws yog txaus los noj cov zaub mov muaj piam thaj ntau, haus dej qab zib carbonated. Yog tias koj muaj cov tshuaj "Glucagon" rau ntawm txhais tes, muab ib qho kev txhaj tshuaj.
Kev sib cuam tshuam ntawm insulin soluble tib neeg hloov kho noob nrog lwm yam tshuaj
Nrog kev siv tshuaj yaj yeeb ntau dhau, hypoglycemia (hws txias, tsis muaj zog, pallor ntawm daim tawv nqaij, tshee hnyo, palpitations, poob siab, plab hnyuv hauv ob txhais ceg, tes, tus nplaig, daim di ncauj, tshaib plab, mob taub hau), cramps, hypoglycemic coma. Kev Kho Mob: tus neeg mob tuaj yeem tshem tawm qhov mob ntshav qab zib tsawg ntawm nws tus kheej los ntawm kev noj cov zaub mov uas muaj tshuaj carbohydrates lossis qab zib. Glucagon yog muab tshuaj subcutaneously, tso ntshav, tshuaj pleev ib ce, lossis tov tshuaj hypertonic dextrose yog muab tshuaj rau qhov mob ntshav qab zib, nrog qhov tsis nco qab, txog 20-40 ml (txog li 100 ml) ntawm 40% dextrose tov yog txhaj rau qhov mob kom txog thaum tus neeg mob tsis hnov qab.
Lub Npe Tsis Muaj Lwm Lub Npe (Lub Koom Tes Ua Haujlwm):
Txhaj tshuaj tov 3 ml - xim tsis muaj iav iav daim ntawv (5) - contour cell ntim (1) - ntim cov duab los qhia.
Cov tshuaj raug pom zoo rau kev siv nyob rau hauv cov xwm txheej hauv qab no:
- Tus mob ntshav qab zib insulin-tiv thaiv kab mob ntshav qab zib hom (hom 1),
- cov ntshav qab zib tsis-insulin-tiv thaiv ntshav qab zib mellitus (hom 2): theem ntawm kev tawm tsam cov tshuaj tiv thaiv kab mob hauv lub qhov ncauj, ib feem tawm tsam cov tshuaj no (thaum siv tshuaj kho mob), nrog cov kab mob sib kis, kev khiav haujlwm, thiab cev xeeb tub.
Cov chaw muag tshuaj
Kev ua tib neeg cov tshuaj lom neeg tsim tshuaj lom neeg insulin yog ib qho kev luv luv ua yeeb yam insulin. Cov tshuaj tiv thaiv nrog kev lees paub tshwj xeeb ntawm lub sab nraud ntawm lub hlwb, cov tshuaj tsim cov tshuaj insulin receptor. Los ntawm kev ua kom muaj cov cAMP ntau ntau (hauv cov qog hlwb thiab cov roj ntsha) los yog nkag mus rau hauv lub cell, qhov no ua rau cov txheej txheem hauv cov cell, nrog rau kev tsim qee cov enzymes tseem ceeb (pyruvate kinase, hexokinase, glycogen synthetase thiab lwm tus). Qhov kev txo qis hauv cov ntshav hauv lub cev yog vim muaj ntau ntxiv thiab nqus tau los ntawm cov ntaub so ntswg, nce ntxiv ntawm kev thauj mus los rau hauv intracellular, stimulation ntawm glycogenogenesis, lipogenesis, synthesis protein, txo tus nqi ntawm cov piam thaj los ntawm lub siab thiab lwm cov txheej txheem. Thaum muab tshuaj subcutaneously, cov nyhuv ntawm cov tshuaj tshwm sim tom qab kwv yees li 20 txog 30 feeb, dhau los ua qhov siab tshaj plaws tom qab 1 txog 3 teev thiab kav ntev txog 5 txog 8 teev (nyob ntawm koob tshuaj). Lub sijhawm ntawm cov tshuaj yog nyob ntawm qhov chaw thiab txoj kev ntawm kev tswj hwm, koob tshuaj thiab tau hais tawm tus tib neeg tus yam ntxwv. Kev ua tiav ntawm kev nqus ntawm cov tshuaj yog nyob ntawm lub koob tshuaj, thaj chaw txhaj tshuaj (ncej puab, plab, pob tw), txoj hauv kev ntawm cov thawj coj (subcutaneous, intramuscularly), qib ntawm insulin hauv tshuaj, thiab lwm yam. Hauv cov ntaub so ntswg, cov tshuaj tau faib tsis ncaj. Nws tsis nkag rau hauv niam mis thiab los ntawm qhov chaw tiv thaiv. Feem ntau nyob rau hauv ob lub raum thiab mob siab, nws yog rhuav tshem los ntawm insulinase. Kev tshem tawm ib nrab-lub neej ua los ntawm ob peb mus rau 10 feeb. 30 - 80% yog tawm los ntawm lub raum.
Hom 2 mob ntshav qab zib mellitus (theem ntawm kev tawm tsam ntawm qhov ncauj hypoglycemic, ib feem tawm tsam cov tshuaj tiv thaiv qog ntshav qab zib (kev kho mob sib xyaw)), hom ntshav qab zib hom 1, hyperosmolar thiab ketoacidotic coma, ntshav qab zib ketoacidosis, ntshav qab zib mellitus uas tau tsim thaum cev xeeb tub (yog tias kev noj zaub mov tsis zoo) rau kev siv sib quas ntus hauv cov neeg mob ntshav qab zib nrog cov mob kis nrog hyperthermia, nrog rau kev raug mob tom ntej, kev phais mob, kev yug menyuam, nrog cov teeb meem metabolic, ua ntej hloov mus rau kev kho mob nrog kev siv tshuaj insulin kom ntev.
Txoj kev rau kev siv cov tshuaj insulin soluble tib neeg kev tsim kho thiab koob tshuaj
Cov kab ke ntawm kev tswj hwm thiab cov tshuaj ntawm cov tshuaj tau tsim los ntawm tus kheej, nyob rau hauv txhua kis, raws li theem ntawm cov piam thaj hauv cov ntshav ua ntej thiab 1 mus rau 2 teev tom qab noj mov, thiab tseem nyob ntawm tus yam ntxwv ntawm cov kab mob pathology thiab qib ntawm glucosuria. Cov tshuaj tau muab 15-30 feeb ua ntej noj mov subcutaneously (qhov feem ntau txoj kev ntawm kev coj noj coj ua), ncau, intramuscularly. Nrog rau cov mob ntshav qab zib tsis xeev plab, ketoacidosis uas mob ntshav qab zib, thaum phais mob, mob leeg thiab intramuscularly. Qhov ntau zaus ntawm kev tswj hwm ntawm cov tshuaj thaum lub sij hawm monotherapy feem ntau yog 3 zaug hauv ib hnub (tej zaum txog li 5-6 zaug hauv ib hnub, yog tias tsim nyog). Yuav kom zam kev txhim kho ntawm lipodystrophy (hypertrophy lossis atrophy ntawm subcutaneous rog), qhov chaw txhaj tshuaj yuav tsum tau hloov txhua zaus. Qhov nruab nrab txhua hnub koob tshuaj yog 30 - 40 PIECES, rau cov menyuam yaus - 8 PIECES, tom qab ntawd qhov nruab nrab txhua hnub - 0.5-1 PIECES / kg lossis 30-40 PIECES 1-3 zaug hauv ib hnub, tej zaum txog li 5-6 zaug hauv ib hnub, yog tias tsim nyog. Yog tias qhov koob tshuaj txhua hnub ntau dua 0.6 U / kg, ces cov tshuaj insulin yuav tsum ua raws li 2 koob lossis ntau dua kev txhaj tshuaj hauv qhov sib txawv ntawm lub cev. Muaj peev xwm ua ke nrog insulins ntev-ua yeeb yam. Cov roj hmab stopper so nrog ethanol tom qab tshem lub hau txhuas yog punctured nrog rab koob koob txhaj koob tshuaj tivthaiv thiab cov tshuaj insulin yog sau los ntawm vial.
Nco ntsoov xyuas cov tshuaj rau pob tshab ua ntej noj tshuaj insulin los ntawm vial. Cov tshuaj tsis tuaj yeem siv rau clouding, cov tsos ntawm txawv teb chaws lub cev, nag lossis daus ntawm cov tshuaj nyob rau ntawm lub khob ntawm lub raj mis. Qhov kub ntawm cov tshuaj siv yuav tsum sib haum rau chav tsev kub. Hauv cov kab mob kis, ua rau cov thyroid tsis ua haujlwm, hypopituitarism, Addison's disease, mob ntshav qab zib mellitus rau cov neeg tshaj 65 thiab mob raum tsis ua haujlwm, nws yog qhov yuav tsum tau kho lub koob tshuaj insulin. Cov laj thawj rau kev txhim kho hypoglycemia tuaj yeem yog: hloov tshuaj, insulin noj ntau dhau, hla zaub mov, mob plab, ntuav, mob lub cev, hloov chaw txhaj tshuaj (mob plab, ncej puab, xub pwg), pathology uas txo cov kev xav tau ntawm insulin (kab mob siab heev ntawm lub siab thiab lub raum, thiab kuj hypofunction ntawm lub caj pas pituitary, adrenal cortex lossis lub qog caj pas), sib cuam tshuam nrog lwm yam tshuaj. Nws muaj peev xwm txo qis ntshav qabzib thaum hloov tus neeg mob los ntawm tsiaj insulin mus rau tib neeg insulin. Hloov chaw ntawm tus neeg mob rau tib neeg cov tshuaj insulin yuav tsum tau nqa tawm tsuas yog nyob ntawm kev saib xyuas ntawm tus kws kho mob thiab yuav tsum ua txoj kev kho kom zoo tas mus li. Kev coj mus rau hypoglycemia tuaj yeem cuam tshuam cov peev xwm ntawm cov neeg mob pabcuam kev siv tshuab thiab tshuab ua haujlwm, nrog rau kev koom nrog hauv kev tsheb ntau. Cov neeg mob ntshav qab zib muaj peev xwm tiv thaiv nws tus kheej qhov muaj ntshav qab zib tsawg tsawg xwb los ntawm kev noj cov piam thaj lossis zaub mov uas muaj cov carbohydrates ntau (nws zoo tshaj yog ib txwm muaj tsawg kawg 20 g suab thaj nrog koj). Txhawm rau daws qhov teeb meem ntawm kev kho mob kom haum, nws yog qhov yuav tsum tau ceeb toom rau tus kws kho mob uas tau mus kawm txog yam tshuaj tiv thaiv ntshav qab zib yav dhau los. Thaum siv cov insulin luv luv hauv qee qhov xwm txheej, qhov nce lossis qis dua ntawm cov khoom ntim ntawm adipose ntawm qhov chaw txhaj tshuaj yog ua tau. Los ntawm kev hloov pauv ntawm qhov chaw txhaj tshuaj, lipodystrophy tuaj yeem zam dhau los. Thaum cev xeeb tub, nws yog ib qho tsim nyog yuav tsum coj mus rau hauv tus lej txo qis (hauv 1 hlis thib ib) lossis nce ntxiv (hauv qib thib 2 thiab 3) ntawm cov tshuaj insulin. Qhov xav tau rau insulin tuaj yeem txo qis heev thaum yug menyuam thiab tam sim ntawd. Nrog kev lactation, kev soj ntsuam txhua hnub yog xav tau rau ob peb lub hlis (txog thaum qhov xav tau cov tshuaj insulin nyob ruaj khov). Cov neeg mob uas tau txais ntau dua 100 IU ntawm cov tshuaj insulin ib hnub yuav tsum tau pw hauv tsev kho mob thaum hloov cov tshuaj.
Kev phiv los ntawm insulin soluble tib neeg kev tsim kho tshuab
Kev ua xua rau kev tsis haum tshuaj (angioedema, urticaria, ua pa luv, ua npaws, txo cov ntshav siab),
mob ntshav qab zib (nce tawm hws, pallor ntawm daim tawv nqaij, tawm hws, tshee tshee, tshee tshee, tshaib plab, ntxhov siab, ntxhov siab, mob plab, hauv lub qhov ncauj, tsaug zog, mob taub hau, pw tsaug zog, nyuaj siab, ntshai, txob taus, tsis muaj zog txav, coj txawv txawv, qhov muag tsis pom kev thiab hais lus), hypoglycemic coma, lub cev tsis hnov qab (txog kev txhim kho ntawm lub cev tsis nco qab thiab precomatosis), mob ntshav qab zib acidosis thiab hyperglycemia (nrog rau kev tsis tuaj yeem, txhaj tshuaj qis, noj zaub mov tsis zoo, kis tus kab mob, thiab oradicum): kev nqhis dej, tsaug zog, hyperemia ntawm lub ntsej muag, tsis qab los noj mov, tsis pom kev tsis pom kev zoo (feem ntau thaum pib kho), khaus, hyperemia thiab lipodystrophy (hypertrophy lossis atrophy ntawm subcutaneous adipose nqaij) ntawm qhov chaw txhaj tshuaj, nce titer ntawm cov tshuaj tiv thaiv cov tshuaj tiv thaiv kab mob nrog rau kev nce ntxiv ntawm glycemia, txhaj tshuaj tiv thaiv kab mob nrog tib neeg cov tshuaj insulin, thaum pib kho - cuam tshuam tsis zoo thiab txhaws (lawv yog ib ntus thiab raug tshem tawm nrog kev kho txuas ntxiv).
Noj ntau dhau
Nrog kev siv tshuaj yaj yeeb ntau dhau, hypoglycemia (hws txias, tsis muaj zog, pallor ntawm daim tawv nqaij, tshee hnyo, palpitations, poob siab, plab hnyuv hauv ob txhais ceg, tes, tus nplaig, daim di ncauj, tshaib plab, mob taub hau), cramps, hypoglycemic coma. Kev Kho Mob: tus neeg mob tuaj yeem tshem tawm qhov mob ntshav qab zib tsawg ntawm nws tus kheej los ntawm kev noj cov zaub mov uas muaj tshuaj carbohydrates lossis qab zib. Glucagon yog muab tshuaj subcutaneously, tso ntshav, tshuaj pleev ib ce, lossis tov tshuaj hypertonic dextrose yog muab tshuaj rau qhov mob ntshav qab zib, nrog qhov tsis nco qab, txog 20-40 ml (txog li 100 ml) ntawm 40% dextrose tov yog txhaj rau qhov mob kom txog thaum tus neeg mob tsis hnov qab.
Kev cuam tshuam nrog lwm yam tshuaj
Cov ntaub ntawv ntawm nplooj ntawv tau txheeb xyuas qhov tseeb los ntawm kws kho mob Vasilieva E.I.
Yuav ua li cas xaiv txoj cai piv rau
Hauv khw muag tshuaj, tshuaj feem ntau muab faib ua cov lus ua kom sib piv thiab cov duab analogues. Cov txheej txheem ntawm cov lus txhais suav nrog ib los yog ntau qhov kev dhia tshuaj qub uas muaj kev kho lub cev. Los ntawm cov qauv piv txwv yog cov tshuaj uas muaj cov tshuaj sib txawv, tab sis npaj rau kev kho mob ntawm tib cov kab mob.
Qhov sib txawv ntawm cov kis thiab kab mob
Cov kab mob kis tau yog tshwm sim los ntawm cov kab mob, kab mob, hu ua fungi thiab protozoa. Cov chav kawm ntawm kab mob tshwm sim los ntawm cov kab mob thiab cov kab mob feem ntau zoo sib xws. Txawm li cas los xij, kom paub qhov txawv ntawm qhov ua rau tus mob txhais tau tias xaiv qhov kev kho mob uas yuav pab tau sai sai nrog qhov malaise thiab yuav tsis ua mob rau tus menyuam.
Kev ua xua yog qhov ua rau mob khaub thuas
Qee tus neeg tau paub txog qhov xwm txheej uas tus menyuam yaus nyob ntev thiab ntau lub sijhawm muaj tus mob khaub thuas. Cov niam txiv coj nws mus rau cov kws kho mob, ua cov kev xeem, siv tshuaj, thiab vim li ntawd, tus me nyuam twb sau npe nrog kws kho mob raws li feem ntau mob. Qhov tseeb uas ua rau mob ntsws ua pa heev tsis txheeb xyuas.
Txoj hlab zis: kho mob chlamydial urethritis
Chlamydial urethritis feem ntau pom muaj nyob ntawm txoj kev siv ntawm urologist. Nws tshwm sim los ntawm tus kab mob intracellular parasite Chlamidia trachomatis, uas muaj cov khoom ntawm ob hom kab mob thiab kab mob, uas feem ntau xav tau cov tshuaj tua kab mob ntev mus rau kev siv tshuaj tua kab mob. Nws muaj peev xwm ua rau tsis muaj qhov mob tshwj xeeb ntawm txoj hlab zis rau txiv neej thiab poj niam.
Soluble human genetic engineering insulin: cov lus qhia rau kev siv
Kev tsim kho tshuab insulin yog tsim los rau kev kho tshuaj insulin hauv:
- Hom I, ntshav qab zib hom II: thaum nws tsis tuaj yeem tswj hwm qhov ncauj hypoglycemic los yog lawv qhov ua tsis tau zoo
- Ntshav qab zib ketoacidosis
- Coma
- Mob ntshav qab zib thaum cev xeeb tub (yog tias kev noj zaub mov tsis pab)
- Rau kev siv sib quas ntus siv rau cov neeg mob ntshav qab zib tiv thaiv keeb kwm ntawm cov kab mob sib kis nrog cov kab mob sib xyaw ua ke, hauv kev npaj rau kev phais mob, raug mob, mob plab, lub cev tsis txaus siab, thiab tseem thaum hloov mus rau insulins ntev.
Qhov tshuaj lom neeg hauv tib neeg yog ib feem ntawm cov tshuaj los ntawm cov tuam txhab sib txawv, yog li cov koom haum pabcuam muaj qhov sib txawv ntawm ib leeg.
Nqe: 10 amp. 1 ml txhua - los ntawm 177 rub., Cartridges 5 pcs. 3 ml -
1 ml ntawm kev txhaj tshuaj muaj:
- Cov khoom siv nquag: 100 IU
- Cov khoom siv ntxiv: zinc chloride, glycerol, sodium hydroxide (lossis hydrochloric acid), dej.
Cov tshuaj nyob rau hauv daim ntawv ntawm cov ntshiab, tsis siv kua rau kev siv niam txiv. Ntim hauv ampoules, cwj mem-koob txhaj tshuaj, hwj.
Cov tshuaj yeeb yam luv luv rau siv nrog insulin-tiv thaiv hom 1 lossis ntshav qab zib hom 2. Tom qab nkag mus, nws reacts nrog tshwj xeeb receptors ntawm lub cell daim nyias nyias, uas ua rau kev tsim ntawm insulin-receptor complex, uas nyob rau hauv lem ua kom lub zog ntawm cov cAMP, cov ntws ntawm cov txheej txheem sab hauv hauv lub cell, suav nrog cov synthesis ntawm cov enzymes tseem ceeb.
Qhov qis hauv glycemia yog vim muaj kev thauj khoom ntau ntxiv, kev siv dag zog ntau dua, kev ua kom muaj protein ntau dua sai, thiab cov kua nplaum tsim tawm los ntawm lub siab.
Kev txhim kho ntawm cov nyhuv hypoglycemic tom qab kev txhaj tshuaj tau tshwm sim tom qab 15-30 feeb, nce mus txog qhov siab kawg qhov tseem ceeb tom qab 1-3 teev thiab kav ntev, nyob ntawm qhov loj me ntawm cov tshuaj muab rau. Lub sijhawm ntawm kev ua ntawm qhov kev tawm caj dab cov tshuaj tiv thaiv feem ntau yog txiav txim siab los ntawm qhov ntau npaum, qhov chaw thiab hom kev tswj hwm, thiab cov yam ntxwv ntawm tus neeg mob lub cev.
Cov tshuaj zom cov dej tsis sib haum ntawm cov ntaub so ntswg, tsis hla ntawm tus poj niam thiab mis. Nws tawg feem ntau yog nyob hauv daim siab, ob lub raum nyob rau hauv tus ntawm insulinase. Cov zis hauv cov ntshav tawm ntawm lub cev.
Kev tsim kho tib neeg cov tshuaj engineering insulin yog txhaj hauv qab daim tawv nqaij lossis nkag mus rau qhov lumen ntawm cov leeg. Tus tsuas tshuaj yog xaiv tau ib tus zuj zus raws li qib glycemic. Qhov nruab nrab txhua hnub xav tau rau cov tshuaj yog 0.3-1 IU. Hauv cov neeg mob uas muaj cov tshuaj insulin tsis kam, nws yuav siab dua, thiab hauv cov neeg uas tseem tso cov tshuaj tawm mus, nws yuav qis dua.
Qhov kev txhaj tshuaj yog ua rau ib nrab teev ua ntej noj mov lossis noj cov khoom uas muaj carbohydrate. Txog kev txhaj tshuaj subcutaneous, xaiv thaj chaw ntawm phab ntsa ua ntej ntawm lub plab, ntxiv rau hauv tus ncej sab sauv, pob tw los yog sab hauv cov leeg txha mos. Rau qhov xwm txheej ceev, thaum nws yog qhov tseem ceeb uas yuav tsum hloov pauv sai ntawm qib glycemia, nws zoo dua rau qhov ntsuas hauv plab, vim tias cov tshuaj insulin hauv cov kis no yuav nrawm dua.
Yog tias cov tshuaj tau qhia rau hauv daim tawv nqaij quav, tom qab ntawd qhov no qhov kev pheej hmoo mus rau hauv cov leeg yog qhov tsawg. Txhawm rau tiv thaiv cov tshuaj ntawm cov tshuaj, nws raug nquahu kom tsis rub tawm rab koob li 6-10 vib nas this. Rau kev txhaj tshuaj, koj yuav tsum siv thaj chaw tshiab txhua lub sijhawm kom tsis txhob muaj kev puas tsuaj rau cov txheej txheem dermis thiab subcutaneous.
Kev taw qhia rau hauv txoj leeg yuav tsum muaj kev paub tshwj xeeb thiab kev paub ntau, yog li ntawd, cov txheej txheem no tsuas yog tso cai rau cov kws kho mob muaj peev xwm nkaus xwb.
Ua ntej ntsuas qhov ntsuas ntawm cov tshuaj tiv thaiv kab mob tso tawm los ntawm cov vial lossis ampoule, koj yuav tsum ua kom pom tseeb tias cov pob tshab ntawm cov tshuaj txhaj. Yog tias muaj kev suav nrog hauv nws, ncua lossis ib lub thauv nrog cov tshuaj yuav raug khawb, tawg lossis hno, ces cov tshuaj yog suav tias tsis zoo rau kev tswj hwm. Nws yuav tsum muab pov tseg raws li cov kev cai lees txais.
Ua ntej txhaj tshuaj, koj yuav tsum tau muab cov tshuaj sov kom sov raws li kev nyiam ua kom nws qhov ntsuas kub sib npaug nrog chav sov.
Qhov ntau npaum li cas yuav tsum tau hloov pauv yog tias tus neeg mob ua rau muaj mob lossis cov thyroid tsis ua hauj lwm. Kev kho yuav tsum muaj nyob rau hauv cov ntaub ntawv ntawm Addison tus kab mob, laus lub hnub nyoog, pituitary tsis txaus, mob raum tsis ua haujlwm.
Hypoglycemia tsis tso cai. Nws txoj kev txhim kho yog ua ntej los ntawm kev qhia txog qhov tsis txaus los ntawm cov tshuaj insulin, kev hloov tshuaj tsis raug, tsis noj zaub mov noj, ntuav, raws plab, lub cev ntau dhau, dhau mus ua lub siab thiab / lossis lub raum pathologies, adrenal tsis txaus, ua ke nrog lwm yam tshuaj. Tsis tas li ntawd, theem ntawm glycemia tuaj yeem txo qis tom qab hloov thaj chaw txhaj tshuaj, hloov mus los ntawm tsiaj cov tshuaj insulin. Nyob rau hauv rooj plaub tom kawg, hloov mus rau tib neeg cov khoom yuav tsum tau nqa tawm rau kev kho mob. Nws yog txwv tsis pub hloov cov tshuaj ntawm nws tus kheej.
Isulin cov kua dej
KWV YEEM: pancreatic hormone npaj, nruab nrab ua yeeb yam insulins, tib neeg kev tsim kho tshuab
Rp.: Insulini isophani 5ml (100ME)
S .: 20 ME subcutaneously 2 zaug hauv ib hnub.
TSWV YIM: tsim cov insulin receptor complex rau ntawm daim nyias nyias, nce cAMP, txhawb kev sib txuas ntawm cov enzymes (hexokinase, thiab lwm yam). Kev txo qis hauv cov concentration ntawm cov piam thaj hauv cov ntshav vim muaj kev nce ntxiv hauv nws txoj kev thauj mus los hauv lub cev (nqus los ntawm cov ntaub so ntswg), kev txhawb nqa ntawm lipogenesis, glycogenogenesis, thiab txo qis ntawm cov piam thaj los ntawm daim siab (txo qis hauv kev puas tsuaj ntawm glycogen).
INDICATIONS: T1DM, T2DM: theem ntawm kev tawm tsam ntawm qhov ncauj, cuam tshuam, T2DM rau cov poj niam cev xeeb tub.
TXHEEJ TXHEEM: HS, ntshav qab zib tsawg.
KID:Ntxim rau U pauv: hypoglycemia (pallor ntawm daim tawv nqaij, nce hws, palpitations, tshee tshee, tshaib plab, ntxhov siab, mob plab hnyuv hauv qhov ncauj, gb, hypoglycemic coma).Kev tsis haum tshuaj: daim tawv nqaij ua pob, Quincke's edema. Lwm yam: o tuaj, cov teeb meem tig mus los uas tsis yooj yim. Cov tshuaj tiv thaiv hauv zos: hyperemia, o thiab khaus ntawm qhov chaw txhaj tshuaj, nrog rau siv sijhawm ntev - lipodystrophy ntawm thaj chaw txhaj tshuaj.
KWV YEEM: cov tshuaj tiv thaiv kab mob hauv lub qhov ncauj, cov tshuaj tiv thaiv kab mob tiv thaiv kab mob txo qis tus neeg sawv cev, biguanides
Rp .: Tab. Metformini 0.5
S .: 1 ntsiav tshuaj 2 (lossis 1) zaug ib hnub (yav tsaus ntuj) tom qab noj mov.
TSWV YIM: nce insulin rhiab heev, txhawb kev ntes ntawm qabzib los ntawm cov leeg pob txha, txhawb kev ua haujlwm rau lub cev glycolysis, txo cov ntshav qabzib hauv cov hnyuv thiab nws cov khoom lag luam hauv lub siab, txo qis glucagon hauv ntshav thiab LDL, roj cholesterol, thiab triglycerides, thiab txo qhov qab los noj mov thiab lub cev hnyav.
INDICATIONS: T2DM (tshwj xeeb tshaj yog rau cov rog dhau) nrog kev noj haus tsis ua haujlwm.
TXHEEJ TXHEEM: HF, lub raum / mob siab / ua pa / lub plawv tsis ua haujlwm, lub plawv nres, ntshav liab, lub cev qhuav dej, kab mob kis, haus dej cawv, metabolic acidosis, cev xeeb tub, lactation.
KID: GIT: thaum pib - tsis nco qab haus huv, zawv plab, xeev siab, ntuav, pom tus mob plab, mob plab, muaj xim nyob rau hauv lub qhov ncauj. CCC: megaloblastic anemia. Kev lom zem hauv lub cev: hypoglycemia, tsis tshua muaj cov kab mob mob ntsws loog (tsis muaj zog, tsaug zog, hypotension, tiv thaiv bradyarrhythmia, ua tsis taus pa, mob plab, mob plab, myalgia, hypothermia). Daim tawv nqaij: xoo pob, pob khaus.