Amoxiclav ntsiav tshuaj 625 cov lus qhia rau siv

Ntawm cov tshuaj tua kab mob ntawm cov tshuaj Amoxiclav 625, kev tshuaj xyuas cov neeg mob thiab cov kws tshaj lij feem ntau yog cov cim. Cov tshuaj yog suav tias yog cov tshuaj tua kab mob ntau tshaj plaws thiab yog li ntawd tau txais kev lees paub dav. Vim tias qhov kev pom dav dav ntawm kev nqis tes, kev nyab xeeb ntawm kev siv hauv cov menyuam yaus thiab cov pojniam muaj menyuam, cov Amoxicillin Clavulanate yuav luag tag nrho cov kev ua haujlwm ntawm kev kho mob ua pa rau mob ua pa thiab cov kab mob genitourinary.

Cov yam ntxwv ntawm kev tso tawm thiab analogues

Cov tshuaj "Amoxiclav 625" yog tsim los ntawm Slovenian lub tuam txhab Lek thiab tau muab tso rau qhov tshuaj uas nws cov tshuaj ua haujlwm yog aminopenicillin amoxicillin thiab clavulanic acid. Thawj ua lub luag haujlwm ntawm tshuaj tua kab mob, thiab cov kua qaub tiv thaiv cov kab mob beta-lactamases. Raws li ib feem ntawm cov tshuaj "Amoxiclav 625 mg" ntsiav tshuaj muaj 500 mg ntawm cov tshuaj tua kab mob, 125 mg ntawm clavulanate thiab tshem tawm.

Cov tshuaj mob nrog cov tshuaj nquag amoxicillin muaj nyob hauv ntau lub npe. Cov tiv thaiv cov tshuaj tiv thaiv ntau tshaj yog cov tiv thaiv aminopenicillins: Amoklav, Augmentin, Flemoklav, Amklav, Farmentin, Amoksikar Plus, Augmenta, Medoklav. Tseem muaj cov penicillins uas tsis muaj kev tiv thaiv, uas yog chav kawm analogues ntawm Amoxiclav: Amoxicillin, Amoxicar, Amosin, Hikontsil thiab lwm yam. Lawv qhov kev ua tau zoo suav hais tias yog kwv yees li qub.

Qhov tseeb ntawm cov tshuaj

Txog tshuaj "Amoxiclav 625" kev tshuaj xyuas ntawm cov kws tshaj lij yog qhov tsis muaj tseeb. Qhov no yog cov tshuaj zoo, yog ib qho ntawm ob peb qhov ncauj tshuaj tua kab mob uas muaj ob peb phiv. Vim li no, nws tau siv rau hauv txhua kis uas tsim nyog ntawm amoxicillin. Ntxiv mus, Amoxiclav yog tus sawv cev ntawm kev npaj ua ke. Nws muaj kev tiv thaiv los ntawm clavulanic acid los ntawm penicillinase, ib qho enzyme uas rhuav tshem lub nplhaib cov kabmob tiv thaiv lactam. Ua tsaug rau kev tiv thaiv, Amoxiclav tau dhau los ua kev sib raug zoo hauv kev sib txuas nrog microbial hlwb.

Cov lus qhia txuas nrog Amoxiclav 625 kev npaj muaj cov cim qhia txog kev kis kab mob hauv kev kho tshuaj uas cov tshuaj tiv thaiv kab mob tau tso cai siv. Cov no feem ntau txhim kho ua pa, mob plab hnyuv, thiab cov kab mob genitourinary ntawm mob sib khuav lossis mob hnyav. Hauv cov ntawv me, kev kho monotherapy nrog cov tshuaj yog qhov tsim nyog, thaum lub sij hawm nruab nrab thiab hnyav yuav tsum tau kho nyob rau hauv cov chaw ruaj ruaj nrog kev siv tshuaj tiv thaiv. Feem ntau, cov lus qhia piav qhia txog kev taw qhia rau kev siv tshuaj "Amoxiclav 625 mg" raws li hauv qab no:

• kis kab mob ntawm cov kab mob qaum ntawm cov kab mob ua pa (mob ntev thiab mob ua ke ntawm tonsillitis, pharyngitis, sinusitis, otitis media),
• cov kab mob sib kis ntawm cov pa hauv qis qis (mob thiab mob ntev ntawm mob ntsws, mob ntsws),
• cov kab mob genitourinary (pyelonephritis, urethritis, cystitis, salpingoophoritis, pelvioperitonitis, endometritis, kab mob gonorrhea thiab chancroid),
• osteomyelitis mob,
• kis kab mob ntawm cov tawv nqaij, muaj tsiaj kis kab mob, noob nyom nrog cov kab mob ua paug,
• mob thooj.

Rau tus neeg mob, cov ntaub ntawv tseem ceeb ntawm Amoxiclav yog cov lus qhia rau kev siv. 625 mg ntawm cov tshuaj, kws kho peb zaug rau ib tus neeg laus, tuaj yeem kho tau cov kab mob ntawm cov kab mob ntawm lub ntsws ua kom tshwm sim los ntawm cov paj ntoo zoo. Ntxiv mus, nrog mob ua pa nyuaj, ntev ntawm kev kho mob feem ntau 5-7 hnub.

Cov Yuav Tsum Muaj

Kev nyab xeeb ntawm cov tshuaj thiab cov ntaub ntawv teev tsis raug lom ntawm chav kawm penicillin tsis suav nrog qhov tsis pom muaj contraindications.

Lawv muaj me ntsis tshuaj. Lawv cuam tshuam nrog kev muaj cov kab mob concomitant, nrog kev tawm tsam tsis haum, lossis nrog lub cev muaj sia hauv lub cev. Cov tshuaj tiv thaiv yog raws li nram no:

• muaj cov cim qhia ntawm cholestatic jaundice, ib qho kev nce ntxiv ntawm kev ua haujlwm ntawm aminotransferases los yog kev txhim kho kab mob siab los ntawm kev siv Amoxiclav ua ntej, nws cov analogues lossis cov neeg sawv cev ntawm pawg penicillin,
• daim siab ua haujlwm, lymphocytic leukemia, mononucleosis vim yog qhov kev txom nyem ntawm tus lej thiab qhov mob ntawm cov kev mob tshwm sim,
• kev tsis haum tshuaj rau qhov tshuaj lossis cov khoom sib txuas,
• qhia txog qhov tshwm sim ntawm kev tsis haum ntawm lub cev tam sim ntawd thaum noj lwm yam beta-lactam antimicrobial tus neeg sawv cev,
• tus txheeb ze ib ntus contraindications: cev xeeb tub hauv 3 lub hlis, lactation.

Kev Phom Sij Phom Sij

Yog tias nyob hauv tus neeg mob lub keeb kwm muaj qhov qhia pom tias muaj kev fab tshuaj tsis haum hauv zej zog, ces Amoxiclav tsis raug sau tseg. Yog tias anaphylaxis lossis Quincke's edema tau tsim tawm hauv kev teb rau kev noj lwm yam beta-lactam antimicrobials, ces Amoxicillin Clavulanate kuj yuav tsum tsis txhob ua. Tom qab ntawd tus sawv cev ntawm ntau tus mob macrolides nrog cov chav kawm me lossis fluoroquinolone yog cov tshuaj ntawm kev xaiv.

Kev noj tshuaj ntxiv

Tus nqi ntawm Amoxiclav 625 mg, uas yuav tsum tau kho mob, nyob ntawm lub hnub nyoog thiab qhov hnyav ntawm tus neeg mob. Txog kab mob rau kev ua pa, nws yog ib qho muaj nqi txaus los sau txog li 2 gram rau cov neeg laus thiab 1,3 gram rau cov hluas. Nyob rau tib lub sijhawm, Amoxiclav nyob rau hauv ib koob tshuaj 625 mg tsuas yog cov hluas thiab cov tshuaj laus xwb. Rau cov menyuam hnub nyoog qis dua 12 xyoos, muaj cov tshuaj siv nrog koob tshuaj qis dua.

Tus qauv muab tshuaj rau ib tus neeg hnyav tshaj 40 kg thiab ntau dua 12 xyoos yog 625 mg ob zaug ib hnub. Cov neeg laus hnub nyoog tshaj 18 xyoo tau sau tseg 625 mg peb zaug ib hnub. Qhov no yog txaus los kho kev mob ntsws thiab mob ntsws, uas yog, mob tawm sab nraud ntawm daim tawv nqaij, ua pa, thiab cov kab mob genitourinary. Hauv kev kis mob hnyav, 1000 mg (875 mg ntawm amoxicillin thiab 125 clavulanate) raug xaj ob zaug ib hnub. Peb zaug siv 1000 mg.

Sab sij huam

Txawm hais tias qhov dav ntawm qhov ua tau zoo los kho, muaj qee yam tshwm sim. Lawv txuam nrog hauv zos ua tsis tiav ntawm txoj hnyuv thiab lub plab, thiab tseem vim yog qaug cawv ntawm lub cev los ntawm cov khoom noj tsis zoo ntawm cov kab mob, vim tias cov tshuaj tua kab mob ua rau cov kab mob bactericidal.

Feem ntau (1-10%) yog mob ntawm xeev siab, ntuav lossis raws plab uas tshwm sim tom qab siv tshuaj tua kab mob. Ntxiv mus, lawv tshwm sim tom qab 2-4 hnub ntawm kev txais neeg kawm. Tseem ceeb ntxiv rau kev muaj peev xwm ntawm dyspepsia, ib qho kev ua txhaum ntawm cov hnyuv thiab qee cov kab mob concomitant: pancreatitis nrog excretory tsis txaus, enteritis, tus mob tom qab rov mob plab lossis plab hnyuv, mob plab ntev.

Cov pab pawg ntawm cov kev mob tsis sib haum (0.001-0.0001%) suav nrog qhov tsis txaus siab hepatic: nce kev ua haujlwm ntawm aminotransferases thiab cov cim ntawm hepatocyte cytolysis, cholestasis thiab jaundice, leukopenia. Hauv qhov xwm txheej no, qhov zaus ntawm Quincke's edema, anaphylaxis thiab urticaria tseem tsis tau hais tawm. Qhov laj thawj rau qhov no yog maj mam nce ntxiv ntawm cov neeg tsis haum tshuaj vim qhov ua kom ntxov hnov ​​tau cov menyuam yaus.

Tom qab ntawd, qhov no yuav ua rau txo qis kev kho mob tseem ceeb ntawm Amoxiclav. Cov lus qhia rau kev siv 625 milligram ntsiav tshuaj tseem tsis tau txwv tsis pub siv cov niam laus. Txawm li cas los xij, qhov no yuav tshwm sim sai sai. Tom qab ntawd koj yuav tsum tau nrhiav qhov tshuaj tshiab los ntawm pawg aminopenicillins uas muaj cov txiaj ntsig zoo sib xws. Nws yog qhov tsim nyog tias cov tshuaj lom neeg tshiab tau tsim thiab raug sim, txawm li cas los xij, nws qhov kev qhia tseem tsis tau muaj kev lag luam, vim tias Amoxiclav ua tau raws li cov kws kho mob xav tau.

Cev xeeb tub thiab lactation

Raws li FDA, Amoxiclav tsis muaj teebmeem teratogenic.Qhov xaus lus no tau ua tom qab ua cov kev tshawb fawb tsiaj, vim tias tag nrho cov tsiaj piv txwv ntawm cov tshuaj no yog rau FDA qib B (Tebchaws USA). Txawm li cas los xij, vim tias muaj kev ntshai ua kom txaus ntshai ntawm exacerbating toxicosis, Amoxiclav 625 yuav luag tsis tas siv tshuaj thaum cev xeeb tub hauv thawj lub hlis. Hauv II thiab III trimesters, nws tuaj yeem tso cai.

Aminopenicillins nyob rau hauv cov kab nyiaj nkag mus rau hauv niam mis, nrog rau lawv hla mus rau txoj hnyuv ntawm tus menyuam mos. Txawm li cas los xij, nws tsis ua rau muaj kev cuam tshuam tseem ceeb hauv nws lub cev, uas yog vim li cas Amoxiclav 625 tsis tuaj yeem raug tshem tawm thaum lub sijhawm lactation. Muaj kev zam tshwj xeeb yog kev kis rau menyuam yaus kev ua xua lossis kev ua haujlwm tawv nqaij ntawm lub plab lossis lub plab zom mov uas tshwm sim nrog kev siv Amoxicillin. Tom qab ntawd nws yog ib qho tsim nyog yuav tsum tshem tawm leej niam txoj kev haus tshuaj tiv thaiv kab mob antimicrobial, lossis, rau candidiasis ntawm cov leeg mos, kom tsis txhob pub niam mis rau me nyuam noj.

Yeeb tshuaj profile

Amoxiclav 625 ntsiav tshuaj muaj qhov kho tau ntau yam, uas yuav pab kom tsis txhob muaj tshuaj lom. Nws kuj tsis muaj kev cuam tshuam hauv nruab nrab, uas tuaj yeem nqa los ntawm cov neeg mob tsav tsheb lossis lwm yam kev txav mus los. Nws tsis ua rau lub cev tsis nco qab, nco qab, saib xyuas lossis xav.

Txawm li cas los xij, muaj kev quav yeeb tshuaj overdose syndrome. Cov xwm txheej zoo li no tsis tshua muaj tshwm sim thiab muaj tshwm sim thaum tsis tsim nyog noj ib zaug txog 5 los yog ntau dua ntawm cov tshuaj. Cov tsos mob yog cov tsos mob li no: dyspeptic cuam tshuam nrog hnyav hauv plab, tsam plab, raws plab, xeev siab, thiab qee zaum ntuav.

Muaj qee tus neeg mob crystalluria txuam nrog kev noj amoxicillin, qee zaum ua rau kev txhim kho lub raum tsis ua haujlwm. Txawm li cas los xij, qhov tshwm sim no yuav tshwm sim thaum noj cov tshuaj hauv tshuaj kho. Txoj kev kho yog nephroprotection thiab lim ntshav, uas tshem tawm amoxicillin thiab clavulanic acid los ntawm cov ntshav.

Kev tiv thaiv kev nyab xeeb

Rau cov neeg mob lymphocytic leukemia los yog kis mononucleosis, cov tshuaj Amoxiclav 625, cov tshuaj tiv thaiv kab mob analogues thiab nws cov generics tsis qhia vim tias muaj qhov ua rau muaj pob khaus ntsej muag ntau dua. Thiab vim tias qhov txo qis hauv qhov ua tau zoo ntawm kev tiv thaiv qhov ncauj thaum lub sij hawm Amoxicillin txoj kev kho, nws yog ib qho tsim nyog yuav tsum tau muaj kev tiv thaiv tiv thaiv kev tiv thaiv tsis pub muaj menyuam nrog txoj kev thaiv (hnab looj).

Nrog rau kev txhim kho mob raws plab thaum lub sijhawm siv Amoxiclav, kev siv tshuaj tua kab mob tawm thiab kev kho mob ntawm colitis (hemorrhagic lossis pseudomembranous) yuav tsum muaj. Hauv qhov xwm txheej no, kev siv Loperamide tsis tuaj yeem lees txais. Tsis tas li ntawd, kev siv tshuaj Amoxiclav lub sijhawm ntev txhawb txoj kev loj hlob ntawm ntau lub nroog ntawm cov kab mob me me uas tiv thaiv cov tshuaj antimicrobial. Lawv tuaj yeem ua rau muaj kev phom sij ntawm cov kab mob tam sim no.

Paub txog kev sib txuam tshuaj

Cov tshuaj uricosostatic Allopurinol, thaum noj ua ke nrog Amoxiclav, ua rau muaj kev pheej hmoo ntawm tawv nqaij ua pob. Kev siv cov neeg sawv cev uricosuric Probenecid, Oxyfenbutazone, Phenylbutazone, Sulfinpyrazone lossis acetylsalicylic acid txo cov kev tso tawm ntawm aminopenicillin (tab sis tsis yog clavulanic acid), uas nce me ntsis cov tshuaj tua kab mob hauv cov ntshav thiab ntev nws cov kev cuam tshuam.

Kev sib xyaw ntawm cov tshuaj Amoxiclav 625 mg nrog bacteriostatic antimicrobial tus neeg sawv cev yog irrational vim muaj kev sib nrig sib ntawm lawv cov hauj lwm zoo. Lwm yam npaj muaj amoxicillin kuj yuav tsum tsis txhob xyaw nrog bacteriostats: chloramphenicol, macrolides, tetracyclines thiab sulfonamides. Kev sib xyaw nrog cov tshuaj tua kab mob ua rau muaj kev sib txuam ntawm cov tshuaj tua kab mob antimicrobial.

Nws yog irrational siv Amoxiclav thaum lub qhov ncauj tiv thaiv kev kho vim tias qhov kev pheej hmoo ntawm kev nce prothrombin lub sijhawm thiab kev loj hlob ntawm thrombosis. Hauv qhov no, qhov kev ua tau zoo ntawm kev tswj kom tsis txhob muaj me me raug txo.Lwm qhov kev siv tshuaj tua kab mob ntau-kuj-sib cuam tshuam ntawm kev txo qis kev ua haujlwm ntawm kev tiv thaiv qhov ncauj.

Kev siv cov Amoxiclav rau kev kho mob ntawm txoj kev kis mob tshwm sim los ntawm kev kho mob methotrexate ua rau muaj tshuaj lom ntau ntxiv rau tom kawg. Qhov no nce ntxiv ntawm kev muaj peev xwm ntawm thrombocytopenia, mob leukopenia, mob kiav txhab rau sab hauv, mob plab hnyuv thiab voos. Tom qab ntawd nws raug nquahu kom tso cov tshuaj aminopenicillins thiab siv macrolides, txuas ntxiv kev kho ntxiv nrog methotrexate.

Ib yam li tej tshuaj tua kab mob uas muaj ntau yam, Amoxiclav ua rau muaj kev cuam tshuam ntau ntxiv rau cov tshuaj tiv thaiv tsis tau. Kev kho nrog "Warfarin" vim los ntawm kev tawm tsam los ntawm cov kab mob antimicrobial ntawm cov haujlwm tseem ceeb ntawm cov kab mob synthesizing vitamin K ua rau txo qis hauv prothrombin Performance index thiab nce INR. Qhov tshwm sim yog qhov pheej hmoo siab los ntshav.

Txoj kev kho ntawm Antimicrobial Kev Kho Mob

Cov tshuaj "Amoxiclav 625", cov tshuaj analogues thiab nws cov generics muaj cov cuab yeej ntawm kev nce ntxiv ntawm txoj kev pheej hmoo ntawm kev tsim mob raws plab, yog tias siv nrog lwm cov tshuaj tua kab mob. Txhua chav kawm ntawm cov tshuaj tua kab mob ua ke nrog amoxicillin feem ntau muaj peev xwm ua rau mob plab zom mov, uas tsis tuaj yeem kho nrog cov tshuaj uas tiv thaiv peristalsis. Xws li cov tshuaj yog Loperamide thiab nws cov analogues, uas yog contraindicated rau hauv kev kis mob raws plab. Tib lub sijhawm, kev mob raws plab los ntawm kev siv Amoxiclav yuav tsum kho nrog tshuaj tua kab mob.

Dosage daim ntawv

375 mg thiab 625 mg zaj duab xis-ntsiav tshuaj

Ib ntsiav tshuaj muaj

yam tshuaj: amoxicillin li amoxicillin trihydrate 250 mg, clavulanic acid li potassium clavulanate 125 mg (rau ntau npaum 375 mg) lossis amoxicillin li amoxicillin trihydrate 500 mg, clavulanic acid li potassium clavulanate 125 mg (rau kev noj 625 mg),

zam txim: colloidal silicon dioxide, crospovidone, croscarmellose sodium, magnesium stearate, talc, microcrystalline cellulose,

zaj duab xis txheej zaj duab xis: hydroxypropyl cellulose, ethyl cellulose, polysorbate, triethyl citrate, titanium dioxide (E 171), talc.

Cov ntsiav tshuaj, coated nrog zaj duab xis plhaub ntawm dawb lossis yuav luag dawb, octagonal duab nrog lub ntsej muag biconvex, sau nrog "250/125" ntawm ib sab thiab "AMS" ntawm lwm sab (rau ntau npaum ntawm 250 mg + 125 mg).

Cov ntsiav tshuaj, zaj duab xis-coated, dawb lossis yuav luag dawb, oval nrog biconvex nto (rau ntau npaum li 500 mg + 125 mg).

Daim ntawv tso tawm

Muaj nyob hauv daim ntawv ntawm:

• txheej ntsiav tshuaj
• hmoov rau kev ncua,
• lyophilized hmoov rau kev txhaj tshuaj.

Ib qho 375 mg ntsiav tshuaj muaj 250 mg ntawm amoxicillin thiab 125 mg ntawm clavulanic acid.

Cov ntsiav tshuaj 625 mg muaj 500 mg ntawm amoxicillin, 125 mg ntawm clavulonic acid.

Cov muaj mob:

• silicon dioxide (colloid),
• croscarmellose (sodium ntsev),
• magnesium stearate,
• talcum hmoov
• hypromellose,
• ethyl cellulose,
• polysorbate,
• titanium dioxide
• triethyl citrate.

Cov ntsiav tshuaj yog ntim hauv vials, 15 daim txhua. Ib lub thawv ntim ib fwj tshuaj.

Cov tshuaj txhuam kev ncua yog muaj nyob hauv cov iav dub vials, ib lub thawv. Muaj yog ntsuas ntsuas. Cov sib xyaw ua ke ntawm qhov ib txwm siv ncua kev kawm ntawv suav nrog 125 thiab 31.25 mg ntawm cov tshuaj yeeb dej caw, feem. Thaum npaj qhov ncua kev kawm "Amoxiclav Forte", 5 ml ntawm nws muaj ob zaug kev ua si ntau - 250 thiab 62,5 mg, ntsig txog. Cov muaj mob:

• citric acid
• sodium citrate
• sodium benzoate
• carmellose sodium
• silica colloid,
• sodium saccharin
• mannitol
• strawberry thiab qus cherry flavors.

Cov chaw muag tshuaj

Cov Tshuaj Pharmacokinetics

Amoxicillin thiab clavulanic acid yog ua kom yaj tag hauv kev daws teeb meem ntawm pH ntawm lub cev. Ob qho khoom siv tau zoo nqus tom qab kev tswj hwm ntawm qhov ncauj.Nws yog qhov zoo dua rau noj amoxicillin / clavulanic acid lub sijhawm lossis thaum pib noj mov. Tom qab kev tswj hwm ntawm qhov ncauj, lub bioavailability ntawm amoxicillin thiab clavulanic acid yog kwv yees li 70%. Lub zog puab ntawm kev saib xyuas ntawm cov tshuaj nyob rau hauv lub plasma ntawm ob feem sib xyaw zoo ib yam nkaus. Qhov siab tshaj tawm cov dej siab tau mus txog 1 teev tom qab kev tswj hwm.

Qhov ntau ntawm amoxicillin thiab clavulanic acid nyob rau hauv cov ntshav ntshav thaum noj cov tshuaj amoxicillin / clavulanic acid ua ke yog zoo li cov tau pom nrog lub qhov ncauj cais cov tshuaj ntawm qhov sib npaug ntawm amoxicillin thiab clavulanic acid.

Txog 25% ntawm tag nrho cov nyiaj ntawm clavulanic acid thiab 18% ntawm amoxicillin khi rau cov ntshav protein. Qhov ntim ntawm kev faib tawm rau kev tswj hwm qhov ncauj ntawm cov tshuaj yog kwv yees 0.3-0.4 l / kg ntawm amoxicillin thiab 0.2 l / kg ntawm clavulanic acid.

Tom qab kev tswj hwm kev siv tshuaj, ob qho tib si amoxicillin thiab clavulanic acid tau pom nyob hauv lub zais zis, cov tawv nqaij ntawm lub plab hauv plab, tawv nqaij, rog, cov leeg nqaij, synovial thiab peritoneal kua, kua tsib thiab kua paug. Amoxicillin nkag mus rau hauv lub cev tsis zoo ua kua dej.

Amoxicillin thiab clavulanic acid hla qhov chaw tiv thaiv hniav. Ob seem puav leej sib kis mus rau niam mis.

Amoxicillin yog qee cov tso tawm hauv cov zis hauv daim ntawv ntawm tsis muaj zog penicillic acid nyob rau hauv ntau npaum li 10 - 25% ntawm thawj koob tshuaj. Clavulanic acid yog metabolized nyob rau hauv lub cev thiab nthuav tawm hauv cov zis thiab quav, ntxiv rau hauv cov qauv ntawm cov pa roj carbon dioxide nrog cov pa tawm ntawm huab cua.

Qhov nruab nrab kev tshem tawm ib nrab-lub neej ntawm amoxicillin / clavulanic acid yog li 1 teev, thiab qhov nruab nrab tag nrho kev sib tw yog kwv yees li 25 l / teev. Li ntawm 60-70% ntawm amoxicillin thiab 40-65% ntawm clavulanic acid raug tso tawm tsis hloov pauv hauv cov zis thaum thawj 6 teev tom qab noj ib qho tshuaj amoxicillin / clavulanic acid ntsiav tshuaj. Thaum lub sij hawm ntau cov kev tshawb fawb, nws tau pom tias 50-85% ntawm amoxicillin thiab 27-60% ntawm clavulanic acid tau tawm hauv cov zis hauv 24 teev. Qhov loj tshaj plaws ntawm clavulanic acid tau tawm hauv thawj 2 teev tom qab daim ntawv thov.

Kev siv ib txhij ntawm probenecid qeeb ua rau kev tso tawm ntawm amoxicillin, tab sis cov tshuaj no tsis cuam tshuam qhov cuam tshuam ntawm clavulanic acid los ntawm ob lub raum.

Ib nrab-lub neej ntawm amoxicillin zoo ib yam li cov menyuam yaus hnub nyoog 3 hlis txog 2 xyoos, tseem yog menyuam yaus thiab neeg laus. Thaum muab tshuaj rau cov menyuam yaus me (nrog rau cov menyuam mos thaum yug los) hauv thawj lub limtiam ntawm lub neej, cov tshuaj yuav tsum tsis txhob siv ntau dua ob zaug hauv ib hnub, uas cuam tshuam nrog kev hloov lub plawv tsis ua haujlwm ntawm cov menyuam yaus. Vim tias qhov tseeb tias cov neeg laus cov neeg mob feem ntau yuav mob lub raum, lub tshuaj yuav tsum tau txiav txim nrog kev ceev faj rau pawg neeg mob no, tab sis yog tias tsim nyog, kev tshuaj xyuas lub raum kev ua haujlwm yuav tsum tau nqa tawm.

Tag nrho kev tshem tawm ntawm amoxicillin / clavulanic acid nyob rau hauv cov ntshav txo qis hauv cov xaim ncaj qha rau ib qho kev txo qis hauv kev ua haujlwm. Qhov txo qis ntawm amoxicillin tshem tawm yog qhov tshaj tawm piv rau clavulanic acid, txij li ntau dua ntawm amoxicillin yog tawm dhau los ntawm lub raum. Yog li, thaum muab tshuaj rau cov neeg mob uas lub raum tsis ua haujlwm, yuav tsum tau txhaj tshuaj kho kom tsis txhob muaj cov tshuaj amoxicillin ntau ntau thiab tswj cov qib clavulanic acid yuav tsum tau ua.

Thaum muab tshuaj rau cov neeg mob uas lub siab tsis ua hauj lwm zoo, yuav tsum ceev faj thaum xaiv ib koob thiab soj ntsuam daim siab ua haujlwm tas li.

Cov Tshuaj Hauv Tshuaj

Amoxicillin yog tshuaj tua kab mob ib nrab los ntawm pawg neeg penicillin (beta-lactam tshuaj tua kab mob) uas tiv thaiv ib lossis ntau tshaj li cov enzymes (feem ntau hu ua penicillin-khi cov protein) koom nrog biosynthesis ntawm peptidoglycan, uas yog ib qho tseem ceeb qauv ntawm cov kab mob ntawm tes ua phab ntsa.Kev txwv tsis pub peptidoglycan hluavtaws ua rau kev ua haujlwm tsis zoo ntawm lub xovtooj ntawm phab ntsa, feem ntau ua raws li cov cell lysis thiab cell tuag.

Amoxicillin raug pov tseg los ntawm beta-lactamases uas ua los ntawm cov kab mob tiv taus, thiab yog li ntawd, kev ua si spectrum ntawm amoxicillin ib leeg tsis suav nrog cov kab mob me me uas tsim cov enzymes no.

Clavulanic acid yog beta-lactam kev txuam nrog penicillins. Nws inhibits qee qhov beta-lactamases, yog li tiv thaiv qhov ua tsis tiav ntawm amoxicillin thiab nthuav nws cov kev ua haujlwm spectrum. Clavulanic acid nws tus kheej tsis muaj qhov chaw mos ua rau muaj kev cuam tshuam loj heev rau kev kho mob.

Tshaj lub sijhawm dhau los ntawm qhov kev txwv qis tshaj plaws (T> IPC) yog suav tias yog qhov kev txiav txim siab tseem ceeb ntawm cov hauj lwm zoo ntawm amoxicillin.

Ob txoj haujlwm tseem ceeb ntawm kev ua rau amoxicillin thiab clavulanic acid yog:

inactivation los ntawm cov kab mob beta-lactamases uas tsis tau txhawm los ntawm clavulanic acid, suav nrog cov chav kawm B, C thiab D.

ib qho kev hloov pauv ntawm kev sib txuas ua ke ntawm penicillin, uas txo qis kev sib raug zoo ntawm cov tshuaj tua kab mob mus rau lub hom phiaj.

Lub zog tsis haum ntawm cov kab mob lossis cov txheej txheem ntawm lub efflux twj tso kua mis (thauj cov tshuab) tuaj yeem ua rau lossis tswj qhov tsis kam ntawm cov kab mob, tshwj xeeb tshaj yog cov kab mob gram-tsis zoo.

Ciaj ciam qhov tseem ceeb ntawm MIC rau amoxicillin / clavulanic acid yog cov tau txiav txim siab los ntawm European Pawg Neeg Saib Xyuas Kev Tiv Thaiv Antimicrobial Rhiab (EUCAST).

Amoxiclav ntsiav tshuaj thiab hmoov - cov lus qhia rau siv

Rau cov menyuam hnub nyoog qis dua 12 xyoos - 40 mg rau ib phaus ntawm qhov hnyav ib hnub.
Rau cov menyuam yaus uas lub cev hnyav dua 40 kg, cov tshuaj tau sau tseg ua tus laus.

Cov neeg laus tau tshuaj: 375 mg ntsiav tshuaj tau noj txhua 8 teev nyob rau ib hnub, 625 mg ntsiav tshuaj txhua 12 teev. Thaum kws kho mob muab tshuaj rau kho cov mob hnyav, cov koob tshuaj 625 mg txhua 8 teev, lossis 1000 mg txhua 12 teev, raug siv.

Nws yuav tsum raug sau tseg tias cov ntsiav tshuaj kuj yuav txawv ntawm qhov tsis muaj qhov sib piv ntawm cov tshuaj nquag. Yog li, koj tsis tuaj yeem hloov lub ntsiav tshuaj 625 mg (500 g ntawm amoxicillin thiab 125 g ntawm clavulanic acid) nrog ob 375 mg ntsiav tshuaj (250 g ntawm amoxicillin thiab 125 g ntawm clavulanic acid).

Cov qauv hauv qab no yog siv los kho tus kab mob odontogenic. 375 mg ntsiav tshuaj tau noj txhua 8 teev, puag ncig lub moos. 625 mg ntsiav tshuaj tom qab 12 teev.

Yog tias tsim nyog, kev siv tshuaj kho mob rau kev kho mob ntawm cov neeg mob raum yuav tsum coj mus rau hauv tus account creatinine nyob rau hauv cov zis. Cov neeg mob mob siab yuav tsum tau soj ntsuam tas li ntawm lawv txoj haujlwm.

Hmoov rau kev ncua rau cov menyuam mos thiab menyuam yaus txog li 3 hlisCov. Kev muab tshuaj yog nqa tawm siv cov raj ntsuas tshwj xeeb lossis rab diav. Tsuas tshuaj - 30 mg ntawm amoxicillin rau ib phaus ntawm qhov hnyav, ob zaug ib hnub.

Puas txhawj xeeb txog tus mob prostatitis? Txuag txuas

Rau cov menyuam yaus hnub nyoog ntau dua peb lub hlis rau kev kis mob me thiab mob nyhav - 20 mg / kg ntawm lub cev qhov hnyav, thiab rau kis hnyav - 40 mg / kg. Qhov tshuaj thib ob kuj tseem siv rau hauv kev kho mob ntawm kev sib sib zog nqus - mob rau hauv nruab nrab pob ntseg, mob pob txha, mob ntsws, mob ntsws. Ib qho kev qhia tau txuas rau cov tshuaj no, nyob rau hauv uas muaj cov ntxhuav tshwj xeeb uas tso cai rau koj kom laij cov tshuaj xav tau ntawm cov tshuaj rau cov menyuam yaus.

Qhov siab tshaj plaws tau tso cai noj tshuaj txhua hnub ntawm amoxicillin rau cov menyuam yaus yog 45 mg / kg ntawm qhov hnyav, rau cov laus - 6 grams. Clavulanic acid tuaj yeem noj nyob rau ib hnub tsis pub ntau tshaj 600 mg rau cov neeg laus thiab 10 mg / kg rau menyuam yaus.

Ib ntsis txog cov tshuaj

Lek yog lub tuam txhab kev lag luam nto moo tshaj plaws hauv ntiaj teb hauv Slovenia. Amoxiclav 625 tsim tawm ntawm no yog ua raws li kev paub ntawm tus qauv zoo uas yuav tsum muaj thoob plaws txhua theem ua haujlwm.

Txhua qhov kev pabcuam ntawm cov tshuaj muaj cov tshuaj sib xyaw ua ke uas muaj 500 mg ntawm cov tshuaj tua kab mob aminopenicillin amoxicillin thiab 125 mg ntawm clavulanic acid, uas tiv thaiv cov kab mob beta-lactamases, thaum ua kom ntseeg tau ua haujlwm ua haujlwm ntawm cov tshuaj tua kab mob los tiv thaiv cov neeg ua haujlwm sib kis. Excipients kuj tseem yog ib feem ntawm cov tshuaj.

Zaj duab xis txheej ntawm cov ntsiav tshuaj muab kev nplij siab siab tshaj plaws thaum siv.

Hauv koob ntawm aminopenicillins, lwm yam tshuaj ntawm cov tshuaj yog paub, piv txwv:

Cov lus piav qhia tawm ntawm cov foos tso tawm

Cov tshuaj no muaj hauv cov qauv hauv cov ntsiav tshuaj uas muaj xim dawb los yog beige-dawb.Cov ntsiav tshuaj muaj oval biconvex duab.

Ib qho 625 mg ntsiav tshuaj muaj 500 mg ntawm amoxicillin trihydrate nrog 125 mg ntawm clavulanic acid (potassium ntsev).

Cov ntsiav tshuaj tuaj yeem tsim rau hauv cov kaus poom yas (15 ntsiav tshuaj txhua) lossis hauv cov kua xaim txhuas ntawm 5 lossis 7 daim.

1000 mg ntsiav tshuaj kuj raug coated, muaj ib daim duab oblong nrog beveled sawv. Ntawm ib sab ntawm lawv yog cov luam tawm ntawm "AMS", nyob rau lwm yam - "875/125". Lawv suav nrog 875 mg ntawm cov tshuaj tua kab mob thiab 125 mg ntawm clavulanic acid.

Dab tsi kis tau siv

Feem ntau cov kws tshaj lij nqaim pom zoo tias cov kws kho mob qhov ncauj Amoxiclav 625 muaj cov tshuaj tua kab mob zoo thaum amoxicillin qhia. Qhov tsawg kawg nkaus ntawm cov kev mob tshwm sim ua rau cov tshuaj sib xyaw ua ke ua ib qho muaj txiaj ntsig zoo thiab muaj txiaj ntsig zoo nyob hauv kev tawm tsam cov kab mob microbes nrog kev txhim kho sai ntawm cov kab mob genitourinary lossis mob hnyuv ntawm cov mob sib khuav me / mob hnyav, mob ua pa ntawm lub sijhawm sib txawv ntawm lub xyoo. Penicillinase - ib qho enzyme uas zom cov lactam nplhaib ntawm cov tshuaj tua kab mob, yog qhov tsis muaj zog ua ntej raug rau clavulanic acid. Amoxiclav 625, raws li cov lus qhia rau kev siv, feem ntau siv rau hauv kev kho mob monotherapy, txawm li cas los xij, muaj rooj plaub thaum kev kho mob yog tsim nyog nrog cov txheej txheem ntawm cov tshuaj tua kab mob hauv cov chaw kho mob hauv qab tswj hwm nruj thiab nruj ntawm cov neeg kho mob.

Raws li tau qhia hauv cov lus qhia, siv cov tshuaj "Amoxiclav 625", koj tuaj yeem tiv thaiv zoo tag nrho nrog rau cov kab mob hauv qab no:

Kev siv ntau tshaj plaws yog Amoxiclav 625 hauv kev kho mob ua pa rau kab mob ua pa los ntawm aerobic gram-zoo cov kab mob me me. Lub sij hawm ntawm kev siv tshuaj triple niaj hnub los ntawm ib tus neeg laus hauv qhov no yuav tsis pub dhau 7 hnub.

Zam kev haus yog tias:

1. Muaj ib tus kab mob concomitant
2. Ua rau muaj kev fab tshuaj tsis haum,
3. Qhov mob ntawm lub cev tsis suav nrog kev siv tshuaj tua kab mob,
4. Muaj qhov pheej hmoo ntawm kev cholestatic daj ntseg,
5. Nyob rau hauv chav kawm ntawm kev txhim kho mob siab rau mob los ntawm kev siv ua ntej Amoxiclav 625,
6. Hepatic tsis ua haujlwm yuav tshwm sim,
7. Hauv lub xub ntiag ntawm mononucleosis lossis lymphocytic leukemia,
8. Puas yog koj cev xeeb tub los yog pub niam mis.

Yog tias qhov kev pheej hmoo ntawm kev ua xua ntawm ib hom hauv zos tau nce ntxiv, tus kws kho mob xaiv cov tshuaj los ntawm ntau tus macrolides lossis fluoroquinolone.

Kho koob tshuaj

Tus nqi ntawm cov tshuaj siv yuav tsum tau ua kom raug xam raws qhov muaj hnub nyoog thiab hnyav cov ntaub ntawv ntawm tus neeg mob. Rau cov kab mob ua pa, cov neeg mob cov laus yuav tsum tau siv txog 2 gram ntawm Amoxiclav 625 rau kev kho mob, thiab 1.3 grams rau cov hluas. Lwm cov tshuaj muaj koob tshuaj qis dua tuaj yeem kho rau cov menyuam yaus hnub nyoog qis dua 12 xyoos.

Txhawm rau ib txwm ua rau lub cev muaj sia ntawm ib tus neeg lub cev hnyav dua 40 kg thiab laus dua 12 xyoos, kev siv tshuaj txhua hnub yog 625 mg ob zaug. Cov neeg laus tshaj 18 xyoo muaj cai tau txais peb hnub tshuaj Amoxiclav 625 mg. Cov ntim uas tau hais tawm yuav tso cai rau koj kom ua tiav nrog cov mob hnyav thiab mob me ntawm daim tawv nqaij, genitourinary system thiab lub tshuab ua pa. Qhov pom ntawm cov mob hnyav tau hloov kho qhov ntau npaum: 1000 mg ib hnub twg ob zaug. Nws yog tsim nyog sau cia tias nyob rau qee qhov kev siv tshuaj triple ntawm cov tshuaj hauv qhov ntim ntawm 1000 mg yog qhov tso cai.

Teeb meem tshwm sim tuaj

Txawm hais tias txoj kev kho tau zoo tshaj plaws ntawm kev siv tshuaj Amoxiclav 625, nws tsim nyog nco txog cov kev mob tshwm sim tom qab ntawm kev noj:

Zawv plab - tuaj yeem tshwm sim tuaj ntawm kev noj cov tshuaj

Kev ua haujlwm ntawm cov hnyuv thiab lub plab vim qaug cawv ntawm lub cev los ntawm cov khoom lwj hauv cov kab mob hauv lub cev,

"Amoxiclav 625" hauv thawj peb lub hlis thaum cev xeeb tub tsis tau sau tseg, txawm li cas los xij, nyob hauv II thiab III trimesters, nws qhov kev txais tos raug tso cai.

Cov yam ntxwv ntawm cov tshuaj

Cov tshuaj "Amoxiclav 625" hauv cov ntsiav tshuaj muaj qhov tsis muaj txiaj ntsig kho tsis zoo thiab tshem tawm cov tshuaj lom tau.

Cov tshuaj tsis cuam tshuam rau kev ua haujlwm ntawm lub hauv nruab nrab cov hlab hlwb, yog li ntawd, nws tuaj yeem siv los ntawm cov neeg mob uas tsav tsheb lossis tshuab txav. Kev npaj tshuaj tsis ua rau muaj kev ntxhov siab hauv kev nco qab, nco, xav lossis xav.

Tus nqi ntawm cov tshuaj tua kab mob Amoxiclav 625 hauv cov ntsiav tshuaj nws txawv me ntsis hauv cov cheeb tsam ntawm peb lub teb chaws thiab yog qhov zoo rau kev siv nyiaj ntawm nruab nrab Lavxias

Anastasia, 28 xyoo: Lub caij nplooj zeeg, tag nrho tsev neeg, nyeg, pib ua khaub thuas. Xyoo no kuv qhib lub caij nyoog ntawm kab mob. (Cov tshuaj ntsuab pab tsis tau qhov tseeb txog kev kho mob, Kuv yuav tsum tau siv tshuaj tua kab mob, tab sis kuv tsis xav tau. Tab sis tom qab siv Amoksiklav kuv hloov siab, vim tias txij lub sijhawm kuv pib noj nws, ob peb hnub tom qab ntawd kuv tau paub meej txog txoj kev noj qab nyob zoo lawm. Kuv muaj peev xwm mus ua haujlwm tau ntxov dua thiab Kuv tsis muaj sijhawm los kis kuv tsev neeg, uas kuv zoo siab ua tsaug. Kuv tau coj Amoksiklav 625 los ua haujlwm). Yog tias kuv mob, tamsis no kuv paub yuav rov mob sai dua!

Nikolay, hnub nyoog 43 xyoo: Tsis ntev los no, mus txog lub tsheb loj uas muaj tsheb hauv tsev nres tsheb. Thaj txias heev. Los ntawm yav tsaus ntuj, xws li kev qaug zog tau npog nws lub taub hau. Qhov kub dhia ntawd, snot pib. Kuv tus poj niam qhia kuv kom sai li pib haus cov Amoxiclav ntsiav tshuaj, ntawm pob ntawv nws tau qhia - 625 mg. Kuv feem ntau rattle vodka nrog kua txob, nws tau yooj yim dua thaum sawv ntxov. Thiab tom qab ntawd kuv txiav txim siab los sim, qhov twg kuv tsav tom qab vodka? Thaum sawv ntxov kuv xav tias qhov muag me dua, tab sis thaum kawg, tom qab 5 hnub kuv twb txawb cov ntsiav tshuaj, tsis tas yuav tsum muaj. Tam sim no kuv qhia txhua tus: ob tus nqi yog qhov qub thiab kev txiav txim.

Cov tshuaj muaj pes tsawg leeg

clavulanic acid trihydrate thiab potassium ntsev, uas yog ib qho enzyme inhibitor. Nws zwm rau pab pawg pharmacological

Daim ntawv tso tawmMuaj nyob hauv daim ntawv ntawm:

• txheej ntsiav tshuaj
• hmoov rau kev ncua,
• lyophilized hmoov rau kev txhaj tshuaj.

Ib qho 375 mg ntsiav tshuaj muaj 250 mg ntawm amoxicillin thiab 125 mg ntawm clavulanic acid.

Cov ntsiav tshuaj 625 mg muaj 500 mg ntawm amoxicillin, 125 mg ntawm clavulonic acid.

Cov muaj mob:

• silicon dioxide (colloid),
• croscarmellose (sodium ntsev),
• magnesium stearate,
• talcum hmoov
• hypromellose,
• ethyl cellulose,
• polysorbate,
• titanium dioxide
• triethyl citrate.

Cov ntsiav tshuaj yog ntim hauv vials, 15 daim txhua. Ib lub thawv ntim ib fwj tshuaj.

Cov tshuaj txhuam kev ncua yog muaj nyob hauv cov iav dub vials, ib lub thawv. Muaj yog ntsuas ntsuas. Cov sib xyaw ua ke ntawm qhov ib txwm siv ncua kev kawm ntawv suav nrog 125 thiab 31.25 mg ntawm cov tshuaj yeeb dej caw, feem. Thaum npaj qhov ncua kev kawm "Amoxiclav Forte", 5 ml ntawm nws muaj ob zaug kev ua si ntau - 250 thiab 62,5 mg, ntsig txog. Cov muaj mob:

• citric acid
• sodium citrate
• sodium benzoate
• carmellose sodium
• silica colloid,
• sodium saccharin
• mannitol
• strawberry thiab qus cherry flavors.

Kev sib xyaw ntawm amoxicillin nrog clavulanic acid yog qhov tshwj xeeb ntawm nws txoj kev. Amoxicillin thiab lwm yam tshuaj tua kab mob ntawm cov pab pawg neeg penicillin ua rau cov kab mob tuag los ntawm khi los ntawm khi lawv cov chaw. Txawm li cas los feem ntau

Thaum lub sijhawm siv cov tshuaj no, lawv tau kawm rhuav tshem cov tshuaj tua kab mob no uas siv cov tshuaj beta-lactamase enzyme. Clavulanic acid txo qhov kev ua haujlwm ntawm qhov enzyme, yog li cov tshuaj no muaj qhov kev pom dav dav. Nws tua tau txawm tias hom kab mob tiv taus amoxicillin. Cov tshuaj muaj cov cim zoo bacteriostatic thiab bactericidal cuam tshuam rau txhua hom

(tshwj tsis yog mob methicillin-resistant hom)

Listeria.Cov kab mob Gram-negative kuj tseem nkag rau amoxiclav:

• Bordetella
• brucella
• vaj,
• Klebsiella
• moraxella
• salmonella
• Cuam Tshuam
• shigella
• clostridium thiab lwm tus.

Tsis hais txog ntawm kev sib xyaw nrog kev noj zaub mov, cov tshuaj tau zoo rau hauv lub cev, qhov siab tshaj plaws ntawm cov tshuaj tau mus txog hauv thawj teev tom qab nkag. Nws muaj kev kub ceev thiab ntim ntawm kev faib tawm hauv lub cev - hauv lub ntsws, pleural, kua tshuaj synovial, tonsils, caj pas prostate, cov leeg thiab adipose cov ntaub so ntswg, txhaws ntswg, pob ntseg hauv nruab nrab. Hauv cov ntaub so ntswg, qhov ntau tshaj ntawm amoxiclav yog pom ib teev tom qab qhov siab tshaj plaws hauv ntshav. Hauv cov khoom tsis tseem ceeb, dhau mus rau hauv niam cov kua mis. Amoxicillin yauv raug rhuav tshem ib feem hauv lub cev, thiab clavulanic acid yog metabolized heev. Nws yog tawm los ntawm lub raum. Tawm mus me me yog nqa tawm los ntawm lub ntsws thiab txoj hnyuv. Ib nrab-lub neej nrog ob lub raum zoo yog 1-1.5 teev. Nws yog me ntsis raug tshem tawm los ntawm cov ntshav thaum lim ntshav.
Cov Khoom Qhia

Kev siv cov tshuaj tua kab mob no tau sau rau kev kho mob ntawm ntau yam kabmob sib kis:

• Kab mob ua pa - sinusitis (mob siab los yog mob mus ntev), mob rau sab nruab nrab pob ntseg, pharyngeal abscess, mob ntsws, tonsilopharyngitis, mob ntsws thiab lwm yam.
• Cov kab mob ntawm cov mob txeeb zig - cystitis, pyelonephritis, mob nqaij mob hlwb thiab lwm tus.
• Cov kab mob gynecological, endometritis, septic rho menyuam, salpingitis, thiab lwm tus.
• Kev mob ntawm biliary huam (cholangitis, cholecystitis).
• Kev kis mob ntawm cov kab mob sib txuas thiab pob txha.
• Kev kis mob ntawm cov nqaij mos thiab tawv nqaij (yoov, phlegmon, mob txhab).
• Mob kis ntawm chaw mos (chancroid, mob ncauj lus).
• Cov kab mob Odontogenic uas tus kab mob nkag mus rau hauv lub cev los ntawm kev noj hniav hauv cov hniav.

Amoxiclav ntsiav tshuaj thiab hmoov - cov lus qhia rau siv

Amoxiclav raug tshuaj raws ntau txoj kev. Cov txheej txheem kev tswj hwm yog nyob ntawm lub hnub nyoog thiab qhov hnyav ntawm tus neeg mob, mob hnyav

raum mob thiab

Cov. Lub sijhawm zaum kawg ntawm kev siv tshuaj yeeb yog pib noj mov. Lub chav kawm ntawm cov tshuaj no kav ntev li 5 mus rau 14 hnub, koj siv tsis tau nws ntev dua.

Rau cov menyuam hnub nyoog qis dua 12 xyoos - 40 mg rau ib phaus ntawm qhov hnyav ib hnub.

Rau cov menyuam yaus uas lub cev hnyav dua 40 kg, cov tshuaj tau sau tseg ua tus laus.

Cov neeg laus tau tshuaj: 375 mg ntsiav tshuaj tau noj txhua 8 teev nyob rau ib hnub, 625 mg ntsiav tshuaj txhua 12 teev. Thaum kws kho mob muab tshuaj rau kho cov mob hnyav, cov koob tshuaj 625 mg txhua 8 teev, lossis 1000 mg txhua 12 teev, raug siv.

Nws yuav tsum raug sau tseg tias cov ntsiav tshuaj kuj yuav txawv ntawm qhov tsis muaj qhov sib piv ntawm cov tshuaj nquag. Yog li, koj tsis tuaj yeem hloov lub ntsiav tshuaj 625 mg (500 g ntawm amoxicillin thiab 125 g ntawm clavulanic acid) nrog ob 375 mg ntsiav tshuaj (250 g ntawm amoxicillin thiab 125 g ntawm clavulanic acid).

Cov qauv hauv qab no yog siv los kho tus kab mob odontogenic. 375 mg ntsiav tshuaj tau noj txhua 8 teev, puag ncig lub moos. 625 mg ntsiav tshuaj tom qab 12 teev.

Yog tias tsim nyog, kev siv tshuaj kho mob rau kev kho mob ntawm cov neeg mob raum yuav tsum coj mus rau hauv tus account creatinine nyob rau hauv cov zis. Cov neeg mob mob siab yuav tsum tau soj ntsuam tas li ntawm lawv txoj haujlwm.

Hmoov rau kev ncua rau cov menyuam mos thiab menyuam yaus txog li 3 hlisCov. Kev muab tshuaj yog nqa tawm siv cov raj ntsuas tshwj xeeb lossis rab diav. Tsuas tshuaj - 30 mg ntawm amoxicillin rau ib phaus ntawm qhov hnyav, ob zaug ib hnub.

Rau cov menyuam yaus hnub nyoog ntau dua peb lub hlis rau kev kis mob me thiab mob nyhav - 20 mg / kg ntawm lub cev qhov hnyav, thiab rau kis hnyav - 40 mg / kg. Qhov tshuaj thib ob kuj tseem siv rau hauv kev kho mob ntawm kev sib sib zog nqus - mob rau hauv nruab nrab pob ntseg, mob pob txha, mob ntsws, mob ntsws. Ib qho kev qhia tau txuas rau cov tshuaj no, nyob rau hauv uas muaj cov ntxhuav tshwj xeeb uas tso cai rau koj kom laij cov tshuaj xav tau ntawm cov tshuaj rau cov menyuam yaus.

Qhov siab tshaj plaws tau tso cai noj tshuaj txhua hnub ntawm amoxicillin rau cov menyuam yaus yog 45 mg / kg ntawm qhov hnyav, rau cov laus - 6 grams. Clavulanic acid tuaj yeem noj nyob rau ib hnub tsis pub ntau tshaj 600 mg rau cov neeg laus thiab 10 mg / kg rau menyuam yaus.

Cov lus piav qhia tawm ntawm cov foos tso tawm

Lub hmoov rau tshuaj hno qhov ncauj yog siv rau menyuam yaus. Tsib milliliters ntawm cov kev ua tiav tiav muaj 250 mg ntawm amoxicillin trihydrate thiab 62,5 mg ntawm clavulanic acid potassium ntsev. Los yog, 5 ml tej zaum yuav muaj 125 mg ntawm amoxicillin thiab 31,5 mg ntawm clavulanic acid. Txhawm rau muab qhov kev ncua ib qho qab ntxiag, nws muaj cov tshuaj qab zib thiab cov txiv qab. Hmoov rau kev ncua yog muab ntim rau hauv cov iav dub vials. Qhov ntim ntawm lub hwj yog 35, 50, 70 lossis 140 ml. Cov diav diav yog tso rau hauv lub thawv nrog lub hwj.

Cov tshuaj no muaj hauv cov qauv hauv cov ntsiav tshuaj uas muaj xim dawb los yog beige-dawb. Cov ntsiav tshuaj muaj oval biconvex duab.

Ib qho 625 mg ntsiav tshuaj muaj 500 mg ntawm amoxicillin trihydrate nrog 125 mg ntawm clavulanic acid (potassium ntsev).

Cov ntsiav tshuaj tuaj yeem tsim rau hauv cov kaus poom yas (15 ntsiav tshuaj txhua) lossis hauv cov kua xaim txhuas ntawm 5 lossis 7 daim.

1000 mg ntsiav tshuaj kuj raug coated, muaj ib daim duab oblong nrog beveled sawv. Ntawm ib sab ntawm lawv yog cov luam tawm ntawm "AMS", nyob rau lwm yam - "875/125". Lawv suav nrog 875 mg ntawm cov tshuaj tua kab mob thiab 125 mg ntawm clavulanic acid.

Qhov no yog lub npe ntawm cov hmoov rau kev ncua, muaj nyob hauv 5 ml ntawm 125 mg ntawm amoxicillin thiab 31,5 mg ntawm clavulanic acid. Muaj nyob hauv hwj ntawm 100 ml, hauv thawv ntawv thawv nrog rab diav. Qhov ntau npaum li cas yog qhia hauv seem "Amoxiclav - cov lus qhia rau kev siv."

Amoxiclav 250 ("Amoxiclav Forte")

Nws kuj tseem yog hmoov rau kev ncua, tab sis nws muaj ob koob tshuaj amoxicillin - 250 mg hauv 5 ml thiab 62,5 mg ntawm clavulanic acid. Qhov kev ncua yog hu ua Amoxiclav Forte vim tias qhov tshuaj tiv thaiv ntau ntxiv hauv nws cov tshuaj muaj pes tsawg leeg. Qhov ntau npaum li cas yog qhia hauv seem "Amoxiclav - cov lus qhia rau kev siv."

Cov no yog Amoxiclav ntsiav tshuaj - 625 mg, muaj 500 mg ntawm qhov tseeb tshuaj tua kab mob. Daim ntawv thov thiab koob tshuaj muaj qhia nyob rau hauv seem "Amoxiclav cov lus qhia rau kev siv", thiab cov lus sib xyaw thiab cov yam ntxwv tau teev nyob rau hauv seem "Amoxiclav ntsiav tshuaj".

Cov no yog Amoxiclav ntsiav tshuaj - 1000 mg, muaj 875 mg ntawm cov tshuaj tua kab mob tiag tiag, thiab 125 mg ntawm clavulanic acid. Cov ntawv thov thiab cov koob tshuaj tau qhia nyob rau hauv ntu ntawm cov txheej txheem ntawm kev siv tshuaj, thiab muaj pes tsawg leeg thiab cov khoom hauv cov ntu "Amoxiclav ntsiav tshuaj".

Cov ntsiav tshuaj muaj 500 mg ntawm amoxicillin thiab 125 mg ntawm clavulanic acid. Cov ntawv thov thiab cov koob tshuaj tau qhia nyob rau hauv ntu ntawm cov txheej txheem ntawm kev siv tshuaj, thiab muaj pes tsawg leeg thiab cov khoom hauv cov ntu "Amoxiclav ntsiav tshuaj".

Cov ntsiav tshuaj muaj 875 g ntawm amoxicillin thiab 125 mg ntawm clavulanic acid. Cov ntawv thov thiab cov koob tshuaj tau qhia nyob rau hauv ntu ntawm cov txheej txheem ntawm kev siv tshuaj, thiab muaj pes tsawg leeg thiab cov khoom hauv cov ntu "Amoxiclav ntsiav tshuaj".

Txiv hmab txiv ntoo-flavored instant ntsiav tshuaj muaj 500 mg ntawm amoxicillin thiab 125 mg ntawm clavulanic acid, lossis 875 mg ntawm amoxicillin thiab 125 mg ntawm clavulanic acid.

Thaum noj tshuaj, tej zaum yuav muaj kev ua txhaum ntawm daim siab thiab

(cholestatic), yog tias yav tas los siv cov tshuaj no twb tau siv thiab tus neeg mob tau muaj kev cuam tshuam ntau ntxiv rau cov tshuaj, lossis rau txhua tus penicillins.

Hauv cov neeg mob uas ua xua rau cephalosporins, lossis nyob rau hauv muaj pseudomembranous mob plab, daim siab ua haujlwm lossis lub raum ua haujlwm tsis zoo, cov tshuaj tau raug ua kom zoo.

Hauv cov neeg mob uas muaj mononucleosis lossis mob lymphocytic cov ntshav uas yav tas los tau hais qhia rau ampicillin, yuav pom pob khaus ntawm erythematous yam. Hauv qhov no, cov tshuaj tua kab mob yuav tsum txuas mus ntxiv.

Feem ntau yooj yim kom dhau thiab yooj yim zam los ntawm cov neeg mob. Cov kev mob tshwm sim feem ntau yuav tshwm sim hauv cov neeg laus, zoo li hauv cov neeg mob uas siv Amoxiclav ntev ntev. Feem ntau, cov kev mob tshwm sim thaum lub sijhawm lossis tom qab ua tiav kev kho mob, tab sis qee zaum lawv txoj kev txhim kho tshwm sim ntau lub lis piam tom qab ua tiav cov tshuaj.

Lub plab zom mov. Raws li txoj cai, qhov no yog raws plab, xeev siab, ntuav, nrog rau dyspepsia. Flatulence, stomatitis lossis gastritis, tshem tawm ntawm tus nplaig lossis glossitis, enterocolitis tsis tshua muaj. Lub sijhawm lossis tom qab ua tiav ntawm kev kho mob nrog cov tshuaj no, pseudomembranous colitis tuaj yeem tshwm sim - tus kab mob tshwm sim los ntawm ib qho ntawm cov kab mob ntawm cov kab mob clostridium genus.

Ntshav system. Kev mob ntshav qab zib (suav nrog hemolytic), eosinophilia, txo qis ntawm cov platelets thiab / lossis leukocytes, agranulocytosis kuj tseem tuaj yeem tshwm sim.

Kev tswj hwm leeg tej zaum yuav teb rau kev noj tshuaj nrog mob taub hau, kiv taub hau, ntxhov siab, pw tsaug zog, pom dab, coj tus cwj pwm tsis zoo los yog hyperactivity.

Lub siab. Qhov ntsuas cov neeg mob hepatic nce, nrog rau kev ua ntawm AsAT thiab / lossis AlAT, alkaline phosphatase thiab ntshiab bilirubin asymptomatically nce.

Daim tawv nqaij. Cov tawv nqaij tuaj yeem teb rau amoxiclav kev ua kom tsawg nrog ua pob ua xua, khaus khaus, angioedema, erythema multiforme, tshuaj lom mob epidermal necrolysis, exfoliative dermatitis, Stevens-Johnson syndrome.

Cov kab mob zis - muaj cov tsos ntawm cov ntshav hauv cov zis thiab interstitial nephritis.

Ntev nrog kev siv tshuaj, kub taub hau tuaj yeem tshwm sim,

cov kab noj hniav hauv qhov ncauj, zoo li txaus siab

Amoxiclav thaum cev xeeb tub

Amoxiclav thaum

Nws raug nquahu tsis txhob thov. Qhov kev zam tshwj tsis yog cov xwm txheej uas cov txiaj ntsig ntawm kev noj tshuaj ntau dua qhov muaj mob uas lawv ua Noj cov tshuaj no thaum cev xeeb tub nce qhov pheej hmoo ntawm necrotizing mob plab hauv

Amoxiclav rau menyuam yaus

Rau cov menyuam yaus, ncua hmoov ncua hmoov yog siv, xwm yeem thiab Amoxiclav Forte. Cov txheej txheem ntawm kev thov tau piav qhia hauv tshooj Amoxiclav - txheej txheem kev thov.

Amoxiclav nrog angina

Cov tshuaj tua kab mob rau angina tsuas yog kho mob tsuas yog mob pes nrab thiab theem siab. Amoxiclav, ua tshuaj tua kab mob ntawm cov tshuaj penicillin koob, feem ntau yog tshuaj rau tonsillitis. Nws siv yog qhia tsuas yog thaum cov kab mob hauv daim ntawv ntawm tus kab mob tau paub meej, thiab microflora pathogenic raug kuaj rau qhov rhiab heev rau cov tshuaj no. Hauv kev kho mob tonsillitis hauv menyuam yaus, kev ncua raug siv, cov neeg laus - ntsiav tshuaj. Hauv qhov xwm txheej loj, kev txhaj tshuaj ntawm cov tshuaj tau siv.

Nws yuav tsum nco ntsoov tias cov tshuaj tua kab mob yuav tsum tsis txhob siv rau lub sijhawm ntev, vim tias qhov no nce qhov tsis kam ntawm microflora cov kab mob rau lawv.

Ntau txog mob caj pas

Sib xyaw nrog lwm yam tshuaj

• Nws yog qhov tsis tsim nyog siv ib txhij Amoxiclav thiab kev npaj ntawm anticoagulants tsis ncaj. Qhov no tuaj yeem ua rau nce sijhawm hauv prothrombin lub sijhawm.
• Kev sib cuam tshuam ntawm Amoxiclav thiab allopurinol ua rau muaj kev pheej hmoo ntawm exanthema.
• Amoxiclav txhim kho kev puas tsuaj ntawm metatrexate.
• Koj siv tsis tau ob qho tib si amoxicillin thiab rifampicin - cov no yog cov antagonists, ua ke siv cov tshuaj tua kab mob ua kom tsis muaj zog ntawm ob qho tib si.
• Amoxiclav yuav tsum tsis txhob raug coj ua ke nrog tetracyclines lossis macrolides (cov no yog cov tshuaj tua kab mob bacteriostatic), nrog rau sulfonamides vim tias txo qis hauv cov txiaj ntsig ntawm cov tshuaj no.
• Kev noj cov Amoxiclav txo cov kev ua kom muaj txiaj ntsig zoo hauv cov ntsiav tshuaj.

Sib piv nrog lwm cov tshuaj Yuav ua li cas thiaj zoo dua li Amoxiclav? Kev xaiv ib qho tshuaj tua kab mob los kho ib qho kev kis mob, koj yuav tsum tau ua raws li cov txiaj ntsig los ntawm kev kuaj cov kab mob microflora rau kev hnov ​​mob nrog rau ib qho tshuaj tua kab mob tshwj xeeb. Nws ua rau tsis nkag siab siv ib yam tshuaj uas tsis tua cov kab mob - uas yog, nws tsis kho. Yog li, cov tshuaj tiv thaiv rau cov neeg mob microflora cov kab mob tseem ceeb yuav zoo dua.
Amoxiclav lossis amoxicillin?

Amoxiclav yog ib qho tshuaj zoo dua li amoxicillin, txij li ntau cov kab mob pathogenic tau tsim kev tiv thaiv kab mob rau cov tshuaj tua kab mob no thiab tau kawm los rhuav tshem nws, tiv thaiv nws los ntawm kev qhia nws cov nyhuv bactericidal. Qhov ntxiv ntawm clavulanic acid rau amoxicillin ua rau cov tshuaj tua kab mob no tau ua haujlwm ntau dua, nthuav dav nws cov kev ua haujlwm.

Amoxiclav lossis Augmentin?

Augmentin - ib qho tshuaj sib piv ntawm Amoxiclav, muaj tib yam tshuaj lom.

Xav paub ntxiv txog cov tshuaj Augmentin

Amoxiclav lossis Flemoxin? Flemoxin yog ib yam tshuaj uas muaj cov tshuaj amoxicillin nkaus xwb. Tsis muaj clavulonic acid, nws muaj qhov pom kev ua haujlwm me me, yog li ntawd nws tsuas yog siv yog tias cov kab mob microflora nkag siab cov tshuaj tua kab mob no.

Cov ntaub ntawv ntxiv txog Flemoxin

Amoxiclav lossis Sumamed? Cov sib xyaw ntawm Sumamed suav nrog cov tshuaj tua kab mob azithromycin, uas muaj kev ua haujlwm dav. Cov kev xaiv yuav tsum yog txiav txim siab los ntawm kev kuaj xyuas qhov rhiab ntawm microflora cov kab mob rau ob qho tshuaj tiv thaiv no. Cov kev mob tshwm sim los zoo ib yam.

Ntxiv rau ntawm Sumamed

Cawv Ua Rau Lub Cawv Cawv tsis pub haus cawv thaum lub sij hawm kho nrog Amoxiclav. Kev haus dej haus cawv ua rau txo cov nyhuv antibacterial ntawm cov tshuaj.

Txhais thiab analoguesTxhais:

• Amovikomb,
• Arlet
• Baktoklav,
• Clamosar
• Verklav,
• Medoclave
• Lyclav,
• Panclave
• Ranklav,
• Rapiclav
• Toromentin
• Flemoklav,
• Lub Ecoclave
• Amoxicillin + clavulanic acid (Faiser) thiab lwm yam.

Cov kws kho mob tshuaj xyuas

Anna Leonidovna, kws kho mob, Vitebsk. Amoxiclav muaj txiaj ntsig ntau dua hauv kev kho mob ntawm ntau yam kab mob ua pa tsis xws li nws cov tshuaj tiv thaiv kab mob, amoxicillin. Kuv sau ntawv rau kev kawm txog 5 hnub, tom qab ntawd nws yog qhov tsim nyog yuav tsum tau coj cov tshuaj uas rov qab los kho microflora.

Veronika Pavlovna, urologist. Yawg Kryvyi Rih. Cov tshuaj no muaj cov nyhuv zoo heev rau cov kab mob hauv lub cev ntawm qhov chaw mos. Nws tsis tshua muaj kev phiv tshuaj, tib lub sijhawm kuv muab tshuaj tua kab mob, tom qab noj probiotics los kho microflora ib txwm.

Andrei Evgenievich, tus kws kho mob ENT, Polotsk. Kev siv cov tshuaj no los ntawm kev txhaj tshuaj tso cai rau koj kom sai sai qhov cuam tshuam ntawm kev mob hnyav thiab mob hnyav ntawm ENT kabmob. Cov tshuaj kho cov mob nyob hauv nruab nrab pob ntseg zoo. Ib qho ntxiv, cov neeg mob noj lub txiv qab zib tawm zoo.

Kev Ntsuam Xyuas Rau Neeg Mob

Victoria, Dnipropetrovsk. Siv raws li kws kho mob sau tseg los kho tus mob tonsillitis. Pom 5 hnub. Cov tshuaj tua kab mob pib rau hnub thib 3 mob. Tus kab mob subsided los ntawm ib feem peb. Kuv caj pas nres nres. Yog

, dhau mus rau hauv ob hnub, tom qab nws pib siv cov tshuaj probiotics los kho cov microflora.

Alexandra, lub nroog Lugansk. Cov tshuaj no tau raug tshuaj los ntawm kws kho mob los kho tus mob pyelonephritis. Txoj kev kawm tau 7 hnub. Thawj 3 hnub hno - tom qab ntawd cov ntsiav tshuaj. Qhov hno no zoo dua. Txawm li cas los xij, kev txhim kho pib ncig hnub plaub. Tsis muaj kev mob tshwm sim. Puas yog qhov ncauj qhuav.

Tamara, lub nroog ntawm Boyarka. Lawv txhaj kuv cov tshuaj no rau kev kho mob kis mob rau poj niam. Nws mob heev, cov nqaij doog tseem nyob ntawm thaj chaw txhaj tshuaj. Txawm li cas los xij, tom qab ib lub lim tiam tsis muaj ib txoj kab tseem tshuav hauv lub luag nyav los ntawm cov kab mob tseem ceeb.

Amoxiclav rau menyuam yaus

Lilia Evgenievna, Saransk. Amoxiclav (tshem tawm) kho mob ntsws ntawm peb tus menyuam. Nws muaj hnub nyoog yog 3.5 xyoo. Txog hnub thib peb, kev mob plab hnyuv tau pib, tus kws kho mob tau txiav txim siab probiotics, uas lawv haus tom qab qhov kev kawm tiav rau lwm lub hlis. Kev mob ntsws ntawm txoj hlab ntsws tau swb sai sai - hnub 10, tus me nyuam twb tau zoo nyob. Raws li kuv nkag siab, txhua yam tshuaj tua kab mob yuav tsum tau ntxuav nrog cov kab mob npaj.

Yog tias cov tshuaj siv tau ntev, nws yog ib qho tsim nyog los saib xyuas lub siab ua haujlwm ntawm lub siab, cov ntshav cov ntshav thiab cov raum ntawm tus neeg mob. Yog hais tias tus neeg mob tau kho lub raum lub siab, nws yog qhov tsim nyog yuav tau kho lub koob tshuaj lossis nce ntxiv lub sijhawm ntawm cov koob tshuaj ntawm cov tshuaj. Nws yog qhov zoo dua rau kev noj tshuaj nrog zaub mov. Thaum kis superinfection (qhov pom ntawm microflora tsis raug rau cov tshuaj no), nws yog ib qho tsim nyog yuav tau hloov cov tshuaj. Vim tias qhov ua rau hla kev tsis haum nrog cephalosporins nyob rau hauv cov neeg mob rhiab rau penicillins, nws tsis tsim nyog siv cov tshuaj tua kab mob no ua ke.

Thaum noj tshuaj, koj yuav tsum haus kua ntau hauv cov kua thiaj li zam dhau qhov tsim ntawm amoxicillin muaju hauv cov zis.

Koj yuav tsum paub tias muaj cov koob tshuaj loj heev hauv cov tshuaj tua kab mob hauv lub cev tuaj yeem ua rau muaj qhov tsis zoo rau cov ntshav qabzib (yog Benedict reagent lossis Fleming tov tau siv los txiav txim rau nws). Cov txiaj ntsig zoo dua qub nyob rau hauv qhov no yuav muab kev siv cov tshuaj tiv thaiv enzymatic nrog glucosidase.

Txij li thaum cov kev mob tshwm sim los ntawm cov leeg muaj zog thaum siv yeeb tshuaj, nws yog qhov yuav tsum ua tib zoo tsav tsheb (tsheb) lossis koom nrog kev ua si uas yuav tsum muaj kev xav ntau, kev ceev nrawm thiab kev saib xyuas.

Nws yog tso rau ntawm lub hwj tshuaj.

Cov chaw cia khoom thiab txee lub neej Cia hauv qhov chaw qhuav rau cov menyuam yaus siv tsis tau. Cia kub - tsis tshaj 25 degrees. Txhawm rau siv cov tshuaj tom qab hnub tas sij hawm yog txwv tsis pub.

XAUS! Cov ntaub ntawv tso rau hauv peb lub vev xaib yog cov ntaub ntawv lossis nrov thiab yog muab rau cov neeg tuaj saib thoob plaws kev sib tham. Cov tshuaj ntawm cov tshuaj yuav tsum tau nqa tawm los ntawm tus kws tshaj lij xwb, raws li keeb kwm kev kho mob thiab kev kuaj mob.

Hauv tsab xov xwm no, koj tuaj yeem nyeem cov lus qhia rau kev siv tshuaj yaj yeeb AmoxiclavCov. Muab cov lus pom zoo los ntawm cov neeg tuaj saib rau ntawm thaj chaw - cov neeg tau txais kev pab ntawm cov tshuaj no, nrog rau kev xav ntawm cov kws paub txog kev kho mob txog kev siv Amoxiclav hauv lawv qhov kev coj ua. Qhov kev thov loj yog nquag ntxiv kev tshuaj xyuas koj ntawm cov tshuaj: cov tshuaj tau pab lossis tsis pab ua kom tshem tawm ntawm tus kabmob, muaj dab tsi tshwm sim thiab cov kev mob tshwm sim, tejzaum nws tsis tshaj tawm los ntawm tus tsim khoom hauv cov lus piav qhia. Cov kab ke ntawm Amoxiclav nyob rau hauv muaj cov qauv txheej txheem. Siv rau kev kho mob ntawm ntau yam mob sib kis hauv cov neeg laus, menyuam yaus, nrog rau lub sijhawm cev xeeb tub thiab lactation. Kev haus cawv thiab muaj peev xwm tshwm sim tom qab noj Amoxiclav.

Amoxiclav - yog kev sib xyaw ntawm amoxicillin - semisynthetic penicillin nrog rau kev pom dav ntawm cov tshuaj tiv thaiv kab mob thiab clavulanic acid - ib qho tsis paub tseeb beta-lactamase inhibitor. Clavulanic acid ua rau lub zog ua haujlwm ruaj khov nrog cov enzymes thiab ua kom cov tsis kam ntawm amoxicillin rau cov teebmeem ntawm beta-lactamases uas ua los ntawm cov kab mob me me.

Clavulanic acid, zoo sib xws hauv cov qauv tsim cov tshuaj tua kab mob beta-lactam, muaj qhov ua haujlwm tsis muaj zog tiv thaiv kab mob tua kab mob.

Amoxiclav muaj qhov ntau ntawm cov tshuaj tua kabmob.

Nws nquag ua haujlwm rau cov leeg tsis haum rau amoxicillin, suav nrog cov kab mob ua kom muaj cov beta-lactamases, incl. aerobic gram-cov kab mob zoo, cov kab mob aerobic gram-tsis zoo, cov kab mob anaerobic gram-cov kab mob zoo, cov kab mob gram-negative anaerobes.

Cov Tshuaj Pharmacokinetics

Lub ntsiab pharmacokinetic tseem ceeb ntawm amoxicillin thiab clavulanic acid yog qhov zoo sib xws. Ob qhov sib xyaw ua ke tau zoo tom qab noj cov tshuaj hauv, noj mov tsis cuam tshuam rau qib ntawm kev nqus. Ob qhov sib xyaw ua ke los ntawm cov ntim zoo hauv kev faib tawm hauv lub cev thiab cov nqaij (lub ntsws, nruab nrab pob ntseg, dej pleural thiab peritoneal, lub tsev me nyuam, zes qe menyuam, thiab lwm yam). Amoxicillin tseem nkag mus rau hauv cov kua ntshav synovial, mob siab, lub caj pas prostate, palatine tonsils, cov leeg nqaij, lub zais zis, lub zais ntawm cov ntshav, cov qaub ncaug, lub ntsej muag zais zis. Amoxicillin thiab clavulanic acid tsis nkag rau BBB nrog uninflamed meninges. Amoxicillin thiab clavulanic acid hla lub plab placental thiab nyob rau hauv cov nyiaj taug lw yog tawm hauv niam cov kua mis. Amoxicillin thiab clavulanic acid yog qhov cim los ntawm kev khi qis rau cov ntshav protein.Amoxicillin yog qee cov metabolized, clavulanic acid yog pom meej tias muaj cov metabolism hauv lub zog. Amoxicillin ua tawm los ntawm lub raum yuav luag tsis hloov pauv los ntawm tubular tso pa thiab glomerular pom. Clavulanic acid yog tawm los ntawm glomerular pom, ib feem nyob rau hauv daim ntawv ntawm metabolites.

Cov Khoom Qhia

Cov kab mob kis tau los ntawm cov kab mob raug taus ntawm cov kab mob me me:

• kis kab mob ntawm cov pa hauv siab thiab cov kabmob ENT (suav nrog rau mob siab thiab ntev, mob siab thiab ntev oitis media, pharyngeal abscess, tonsillitis, pharyngitis),
• kis kab mob ntawm cov pa hauv qis (nrog rau kev mob ntsws zoo nrog cov kab mob superinfection, mob ntsws txhaws ntev, mob ntsws),
• mob txeeb zig
• cov kab mob gynecological
• kis tau ntawm daim tawv nqaij thiab cov nqaij mos, nrog rau tsiaj thiab tib neeg tom,
• pob txha thiab mob pob txha mos,
• biliary huam mob (cholecystitis, cholangitis),
• odontogenic tau tus kab mob.

Tso Tawm Cov Ntawv

Hmoov rau kev npaj cov kev txhaj tshuaj rau cov tshuaj tua kabmob (4) 500 mg, 1000 mg.

Hmoov rau qhov kev npaj tawm ntawm kev ncua rau kev tswj hwm qhov ncauj ntawm 125 mg, 250 mg, 400 mg (daim ntawv yooj yim rau cov menyuam yaus).

Zaj duab xis-cov ntsiav tshuaj 250 mg, 500 mg, 875 mg.

Cov lus qhia rau kev siv thiab ntau npaum li cas

Cov neeg laus thiab cov menyuam hnub nyoog 12 xyoos (lossis ntau dua 40 kg ntawm lub cev qhov hnyav): cov koob tshuaj ib txwm rau kev sib kis me me mus rau mob hnyav yog 1 ntsiav tshuaj 250 + 125 mg txhua 8 teev lossis 1 ntsiav tshuaj 500 + 125 mg txhua 12 teev, nyob rau kis mob hnyav thiab mob ntsws ua pa - 1 ntsiav tshuaj 500 + 125 mg txhua 8 teev lossis 1 ntsiav tshuaj. 875 + 125 mg txhua 12 teev .Tej ntsiav tshuaj tsis yog rau cov menyuam hnub nyoog qis dua 12 xyoos (qis dua 40 kg ntawm lub cev qhov hnyav).

Qhov siab tshaj plaws txhua hnub koob tshuaj clavulanic acid (hauv daim ntawv ntawm cov ntsev ntsev) yog 600 mg rau cov neeg laus thiab 10 mg / kg ntawm lub cev hnyav rau cov menyuam yaus. Qhov koob tshuaj txhua hnub ntawm amoxicillin yog 6 g rau cov neeg laus, 45 mg / kg ntawm lub cev hnyav rau cov menyuam yaus.

Lub chav kawm ntawm kev kho mob yog 5-14 hnub. Lub sijhawm tiv thaiv ntawm kev kho mob yog txiav txim los ntawm tus kws khomob koom nrog. Txoj kev kho yuav tsum tsis pub ntev tshaj 14 hnub yam tsis muaj kev kuaj mob zaum ob.

Dosage rau odontogenic kis: 1 tab. 250 +125 mg txhua 8 teev lossis 1 ntsiav tshuaj 500 + 125 mg txhua 12 teev rau 5 hnub.

Muab koob tshuaj rau lub raum tsis ua haujlwm: rau cov neeg mob uas mob raum tsis txaus (Cl creatinine - 10-30 ml / min), cov koob tshuaj yog 1 rooj. 500 + 125 mg txhua 12 teev, rau cov neeg mob uas lub raum tsis ua haujlwm (creatinine Cl tsawg dua 10 ml / min), cov koob tshuaj yog 1 lub rooj. 500 + 125 mg txhua 24 teev

Sab sij huam

Cov kev mob tshwm sim rau feem ntau me me thiab ua ntu zus.

• tsis qab los noj mov
• xeev siab, ntuav,
• zawv plab
• mob plab
• pruritus, urticaria, erythematous pob,
• angioedema,
• anaphylactic kev poob siab,
• ua xua vasculitis,
• exfoliative dermatitis,
• Stevens-Johnson mob
• thim rov qab leukopenia (suav nrog neutropenia),
• thrombocytopenia
• hemolytic anemia,
• eosinophilia
• kiv tob hau, mob taub hau,
• mob nriaj (tej zaum yuav tshwm sim rau cov neeg mob uas lub raum lub raum tsis ua haujlwm thaum noj cov tshuaj loj),
• kev xav ntawm kev ntxhov siab
• insomnia
• interstitial nephritis,
• crystalluria
• kev loj hlob ntawm superinfection (suav nrog candidiasis).

Cov Yuav Tsum Muaj

• ua kom lub cev tsis haum rau ib qho twg ntawm cov tshuaj,
• cov tshuaj tiv thaiv tsis haum hauv keeb kwm rau penicillins, cephalosporins thiab lwm yam tshuaj tua kab mob beta-lactam,
• keeb kwm ua pov thawj ntawm cholestatic jaundice thiab / lossis lwm qhov ua kom lub siab ua tsis zoo los ntawm kev noj cov tshuaj amoxicillin / clavulanic acid,
• mob mononucleosis thiab mob lyukhocytic.

Cev xeeb tub thiab lactation

Amoxiclav tuaj yeem raug tshuaj thaum cev xeeb tub yog tias muaj cov cim qhia meej.

Amoxicillin thiab clavulanic acid hauv qee qhov me yog tawm hauv niam cov kua mis.

Cov lus qhia tshwj xeeb

Nrog rau txoj kev kho mob, cov haujlwm ntawm cov ntshav, daim siab thiab lub raum yuav tsum tau saib xyuas.

Hauv cov neeg mob uas lub raum tsis ua haujlwm uas tsis zoo, yuav tsum tau kho txoj kev noj tshuaj ntau dua lossis nce ntxiv nyob nruab nrab ntawm kev noj tshuaj yog xav tau.

Txhawm rau kom txo qis kev phom sij los ntawm kev mob tshwm sim ntawm txoj hnyuv plab, cov tshuaj yuav tsum tau noj nrog pluas noj.

Kev ntsuam xyuas hauv chaw kuaj: cov tshuaj amoxicillin ntau heev muab qhov tsis zoo tsis haum rau cov ntshav qabzib thaum siv Benedict's reagent lossis Felling's solution. Peb nquahu kom muaj Enzymatic tshua nrog glucosidase.

Nws yog txwv tsis pub siv Amoxiclav nrog rau kev siv cawv ib txhij hauv ib qho twg, vim tias qhov pheej hmoo ua rau lub siab noj thaum noj lawv tib lub sijhawm yog nce ntxiv.

Cuam tshuam rau kev muaj peev xwm tsav tsheb thiab tswj cov tshuab

Tsis muaj cov ntaub ntawv qhia txog qhov tshwm sim tsis zoo ntawm Amoxiclav nyob rau hauv koob tshuaj pom zoo kom muaj peev xwm tsav lub tsheb lossis ua haujlwm nrog cov qauv.

Yeeb tshuaj sib cuam tshuam

Nrog rau kev siv tshuaj ib txhij Amoxiclav nrog antacids, glucosamine, laxatives, aminoglycosides, kev nqus qis qis, nrog ascorbic acid - nce ntxiv.

Diuretics, allopurinol, phenylbutazone, NSAIDs thiab lwm yam tshuaj uas thaiv cov hlab zais pa zais ua rau muaj kev cia siab ntawm amoxicillin (clavulanic acid raug cais tawm tshwj xeeb los ntawm glomerular pom).

Nrog rau kev siv tib txhij ntawm Amoxiclav nce lub tshuaj lom ntawm methotrexate.

Nrog rau kev siv tib txhij ntawm Amoxiclav nrog allopurinol, qhov tshwm sim ntawm exanthema nce.

Muab kev tswj hwm nrog disulfiram yuav tsum raug zam.

Qee qhov xwm txheej, kev noj tshuaj tuaj yeem ua kom ntev dua prothrombin lub sijhawm, hauv qhov no, kev ceev faj yuav tsum tau siv thaum lub sij hawm sau tshuaj anticoagulants thiab cov tshuaj Amoxiclav.

Kev sib xyaw ntawm amoxicillin nrog rifampicin yog antagonistic (muaj kev sib txuam ntawm lub zog tiv thaiv kab mob).

Amoxiclav yuav tsum tsis txhob siv nrog cov tshuaj tua kab mob bacteriostatic (macrolides, tetracyclines), sulfonamides vim tias qhov txo qis hauv Amoxiclav cov neeg ua haujlwm tau zoo.

Probenecid txo qis kev zoo ntawm amoxicillin, ua rau muaj kev paub ntau ntxiv.

Cov tshuaj tua kab mob txo qhov ua tau zoo ntawm kev tiv thaiv qhov ncauj.

Cov tshuaj tiv thaiv ntawm cov tshuaj tua kab mob Amoxiclav

Cov qauv ntawm cov qauv ua haujlwm:

• Amovikomb,
• Amoxiclav Quicktab,
• Arlet
• Augmentin
• Baktoklav,
• Verklav,
• Clamosar
• Lyclav,
• Medoclave
• Panclave
• Ranklav,
• Rapiclav
• Taromentin
• Flemoklav Solutab,
• Lub Ecoclave.

Thaum tsis muaj cov tshuaj analogues ntawm cov tshuaj rau cov tshuaj yeeb dej caw, koj tuaj yeem ua raws cov txuas hauv qab no rau cov kab mob uas pab cuam rau cov tshuaj sib txuas thiab pom cov tshuaj muaj analogues rau kev kho mob nyhuv.

Sab sij huam

Feem ntau yooj yim kom dhau thiab yooj yim zam los ntawm cov neeg mob. Cov kev mob tshwm sim feem ntau yuav tshwm sim hauv cov neeg laus, zoo li hauv cov neeg mob uas siv Amoxiclav ntev ntev. Feem ntau, cov kev mob tshwm sim thaum lub sijhawm lossis tom qab ua tiav kev kho mob, tab sis qee zaum lawv txoj kev txhim kho tshwm sim ntau lub lis piam tom qab ua tiav cov tshuaj.

Lub plab zom mov. Raws li txoj cai, qhov no yog raws plab, xeev siab, ntuav, nrog rau dyspepsia. Flatulence, stomatitis lossis gastritis, tshem tawm ntawm tus nplaig lossis glossitis, enterocolitis tsis tshua muaj. Lub sijhawm lossis tom qab ua tiav ntawm kev kho mob nrog cov tshuaj no, pseudomembranous colitis tuaj yeem tshwm sim - tus kab mob tshwm sim los ntawm ib qho ntawm cov kab mob ntawm cov kab mob clostridium genus.

Ntshav system. Kev mob ntshav qab zib (suav nrog hemolytic), eosinophilia, txo qis ntawm cov platelets thiab / lossis leukocytes, agranulocytosis kuj tseem tuaj yeem tshwm sim.

Kev tswj hwm leeg tej zaum yuav teb rau kev noj tshuaj nrog mob taub hau, kiv taub hau, ntxhov siab, pw tsaug zog, pom dab, coj tus cwj pwm tsis zoo los yog hyperactivity.

Lub siab. Qhov ntsuas cov neeg mob hepatic nce, nrog rau kev ua ntawm AsAT thiab / lossis AlAT, alkaline phosphatase thiab ntshiab bilirubin asymptomatically nce.

Daim tawv nqaij. Cov tawv nqaij tuaj yeem teb rau amoxiclav kev ua kom tsawg nrog ua pob ua xua, khaus khaus, angioedema, erythema multiforme, tshuaj lom mob epidermal necrolysis, exfoliative dermatitis, Stevens-Johnson syndrome.

Cov kab mob zis - muaj cov tsos ntawm cov ntshav hauv cov zis thiab interstitial nephritis.
Nrog lub sijhawm ntev ntawm kev siv tshuaj, kub taub hau, mob plab ntawm lub qhov ncauj ntawm lub qhov ncauj, nrog rau cov neeg mob vwm ntawm lub qhov ncauj, yuav tshwm sim.

Sib xyaw nrog lwm yam tshuaj

• Nws yog qhov tsis tsim nyog siv ib txhij Amoxiclav thiab kev npaj ntawm anticoagulants tsis ncaj. Qhov no tuaj yeem ua rau nce sijhawm hauv prothrombin lub sijhawm.
• Kev sib cuam tshuam ntawm Amoxiclav thiab allopurinol ua rau muaj kev pheej hmoo ntawm exanthema.
• Amoxiclav txhim kho kev puas tsuaj ntawm metatrexate.
• Koj siv tsis tau ob qho tib si amoxicillin thiab rifampicin - cov no yog cov antagonists, ua ke siv cov tshuaj tua kab mob ua kom tsis muaj zog ntawm ob qho tib si.
• Amoxiclav yuav tsum tsis txhob raug coj ua ke nrog tetracyclines lossis macrolides (cov no yog cov tshuaj tua kab mob bacteriostatic), nrog rau sulfonamides vim tias txo qis hauv cov txiaj ntsig ntawm cov tshuaj no.
• Kev noj cov Amoxiclav txo cov kev ua kom muaj txiaj ntsig zoo hauv cov ntsiav tshuaj.

Cov Ntaub Ntawv Ntxiv

Yog tias cov tshuaj siv tau ntev, nws yog ib qho tsim nyog los saib xyuas lub siab ua haujlwm ntawm lub siab, cov ntshav cov ntshav thiab cov raum ntawm tus neeg mob. Yog hais tias tus neeg mob tau kho lub raum lub siab, nws yog qhov tsim nyog yuav tau kho lub koob tshuaj lossis nce ntxiv lub sijhawm ntawm cov koob tshuaj ntawm cov tshuaj. Nws yog qhov zoo dua rau kev noj tshuaj nrog zaub mov. Thaum kis superinfection (qhov pom ntawm microflora tsis raug rau cov tshuaj no), nws yog ib qho tsim nyog yuav tau hloov cov tshuaj. Vim tias qhov ua rau hla kev tsis haum nrog cephalosporins nyob rau hauv cov neeg mob rhiab rau penicillins, nws tsis tsim nyog siv cov tshuaj tua kab mob no ua ke.

Thaum noj tshuaj, koj yuav tsum haus kua ntau hauv cov kua thiaj li zam dhau qhov tsim ntawm amoxicillin muaju hauv cov zis.

Koj yuav tsum paub tias muaj cov koob tshuaj loj heev hauv cov tshuaj tua kab mob hauv lub cev tuaj yeem ua rau muaj qhov tsis zoo rau cov ntshav qabzib (yog Benedict reagent lossis Fleming tov tau siv los txiav txim rau nws). Cov txiaj ntsig zoo dua qub nyob rau hauv qhov no yuav muab kev siv cov tshuaj tiv thaiv enzymatic nrog glucosidase.

Txij li thaum cov kev mob tshwm sim los ntawm cov leeg muaj zog thaum siv yeeb tshuaj, nws yog qhov yuav tsum ua tib zoo tsav tsheb (tsheb) lossis koom nrog kev ua si uas yuav tsum muaj kev xav ntau, kev ceev nrawm thiab kev saib xyuas.

Amoxiclav 625 hais txog cov tshuaj tua kab mob nrog kev pom dav. Nws yog cov tshuaj sib txuam. Nws nyob ntawm pawg loj ntawm penicillins.

Tso cov ntaub ntawv thiab cov nyob ua ke

Tawm nyob rau hauv daim ntawv ntawm:

1. Zaj duab xis-coated ntsiav tshuaj. Cov tshuaj tseem ceeb: amoxicillin 250, 500 thiab 875 mg (muaj nyob hauv daim ntawv ntawm amoxicillin trihydrate) thiab clavulanic acid 125 mg. Cov nkauj muaj ntxiv: silicon dioxide, crospovidone, sodium croscarmellose, magnesium stearate, talc. Cov ntsiav tshuaj muaj nyob rau hauv blisters thiab lub khob ntawm cov iav dub. Ib pob ntawv ntawm cardboard muaj 1 lub raj mis lossis 1 lub hlwv (rau 15 ntsiav tshuaj) thiab cov lus qhia rau siv.
2. Hmoov rau qhov npaj cov ncua kev kawm ntawv rau qhov ncauj cov thawj coj thiab kev npaj ntawm kev daws rau kev txhaj tshuaj rau cov leeg.

Pharmacological kev txiav txim

Amoxiclav ntsiav tshuaj thiab hmoov - cov lus qhia rau siv

Rau cov menyuam hnub nyoog qis dua 12 xyoos - 40 mg rau ib phaus ntawm qhov hnyav ib hnub.
Rau cov menyuam yaus uas lub cev hnyav dua 40 kg, cov tshuaj tau sau tseg ua tus laus.

Cov neeg laus tau tshuaj: 375 mg ntsiav tshuaj tau noj txhua 8 teev nyob rau ib hnub, 625 mg ntsiav tshuaj txhua 12 teev.Thaum kws kho mob muab tshuaj rau kho cov mob hnyav, cov koob tshuaj 625 mg txhua 8 teev, lossis 1000 mg txhua 12 teev, raug siv.

Nws yuav tsum raug sau tseg tias cov ntsiav tshuaj kuj yuav txawv ntawm qhov tsis muaj qhov sib piv ntawm cov tshuaj nquag. Yog li, koj tsis tuaj yeem hloov lub ntsiav tshuaj 625 mg (500 g ntawm amoxicillin thiab 125 g ntawm clavulanic acid) nrog ob 375 mg ntsiav tshuaj (250 g ntawm amoxicillin thiab 125 g ntawm clavulanic acid).

Cov qauv hauv qab no yog siv los kho tus kab mob odontogenic. 375 mg ntsiav tshuaj tau noj txhua 8 teev, puag ncig lub moos. 625 mg ntsiav tshuaj tom qab 12 teev.

Yog tias tsim nyog, kev siv tshuaj kho mob rau kev kho mob ntawm cov neeg mob raum yuav tsum coj mus rau hauv tus account creatinine nyob rau hauv cov zis. Cov neeg mob mob siab yuav tsum tau soj ntsuam tas li ntawm lawv txoj haujlwm.

Hmoov rau kev ncua rau cov menyuam mos thiab menyuam yaus txog li 3 hlisCov. Kev muab tshuaj yog nqa tawm siv cov raj ntsuas tshwj xeeb lossis rab diav. Tsuas tshuaj - 30 mg ntawm amoxicillin rau ib phaus ntawm qhov hnyav, ob zaug ib hnub.

Puas txhawj xeeb txog tus mob prostatitis? Txuag txuas

Rau cov menyuam yaus hnub nyoog ntau dua peb lub hlis rau kev kis mob me thiab mob nyhav - 20 mg / kg ntawm lub cev qhov hnyav, thiab rau kis hnyav - 40 mg / kg. Qhov tshuaj thib ob kuj tseem siv rau hauv kev kho mob ntawm kev sib sib zog nqus - mob rau hauv nruab nrab pob ntseg, mob pob txha, mob ntsws, mob ntsws. Ib qho kev qhia tau txuas rau cov tshuaj no, nyob rau hauv uas muaj cov ntxhuav tshwj xeeb uas tso cai rau koj kom laij cov tshuaj xav tau ntawm cov tshuaj rau cov menyuam yaus.

Qhov siab tshaj plaws tau tso cai noj tshuaj txhua hnub ntawm amoxicillin rau cov menyuam yaus yog 45 mg / kg ntawm qhov hnyav, rau cov laus - 6 grams. Clavulanic acid tuaj yeem noj nyob rau ib hnub tsis pub ntau tshaj 600 mg rau cov neeg laus thiab 10 mg / kg rau menyuam yaus.

Cov lus piav qhia tawm ntawm cov foos tso tawm

Cov tshuaj no muaj hauv cov qauv hauv cov ntsiav tshuaj uas muaj xim dawb los yog beige-dawb. Cov ntsiav tshuaj muaj oval biconvex duab.

Ib qho 625 mg ntsiav tshuaj muaj 500 mg ntawm amoxicillin trihydrate nrog 125 mg ntawm clavulanic acid (potassium ntsev).

Cov ntsiav tshuaj tuaj yeem tsim rau hauv cov kaus poom yas (15 ntsiav tshuaj txhua) lossis hauv cov kua xaim txhuas ntawm 5 lossis 7 daim.

1000 mg ntsiav tshuaj kuj raug coated, muaj ib daim duab oblong nrog beveled sawv. Ntawm ib sab ntawm lawv yog cov luam tawm ntawm "AMS", nyob rau lwm yam - "875/125". Lawv suav nrog 875 mg ntawm cov tshuaj tua kab mob thiab 125 mg ntawm clavulanic acid.

Amoxiclav 125

Amoxiclav 250 ("Amoxiclav Forte")

Amoxiclav 500

Amoxiclav 875

Amoxiclav 625

Amoxiclav 1000

Amoxiclav Quicktab

Cov Yuav Tsum Muaj

Thaum noj cov tshuaj, tej zaum yuav muaj kev ua txhaum ntawm daim siab thiab jaundice (cholestatic), yog tias cov tshuaj no tau siv yav tas los thiab tus neeg mob tau muaj kev cuam tshuam ntau dua rau cov feem ntawm cov tshuaj, lossis rau txhua yam penicillins.

Hauv cov neeg mob uas ua xua rau cephalosporins, lossis nyob rau hauv muaj pseudomembranous mob plab, daim siab ua haujlwm lossis lub raum ua haujlwm tsis zoo, cov tshuaj tau raug ua kom zoo.

Hauv cov neeg mob uas muaj mononucleosis lossis mob lymphocytic cov ntshav uas yav tas los tau hais qhia rau ampicillin, yuav pom pob khaus ntawm erythematous yam. Hauv qhov no, cov tshuaj tua kab mob yuav tsum txuas mus ntxiv.

Sab sij huam

Feem ntau yooj yim kom dhau thiab yooj yim zam los ntawm cov neeg mob. Cov kev mob tshwm sim feem ntau yuav tshwm sim hauv cov neeg laus, zoo li hauv cov neeg mob uas siv Amoxiclav ntev ntev. Feem ntau, cov kev mob tshwm sim thaum lub sijhawm lossis tom qab ua tiav kev kho mob, tab sis qee zaum lawv txoj kev txhim kho tshwm sim ntau lub lis piam tom qab ua tiav cov tshuaj.

Lub plab zom mov. Raws li txoj cai, qhov no yog raws plab, xeev siab, ntuav, nrog rau dyspepsia. Flatulence, stomatitis lossis gastritis, tshem tawm ntawm tus nplaig lossis glossitis, enterocolitis tsis tshua muaj. Lub sijhawm lossis tom qab ua tiav ntawm kev kho mob nrog cov tshuaj no, pseudomembranous colitis tuaj yeem tshwm sim - tus kab mob tshwm sim los ntawm ib qho ntawm cov kab mob ntawm cov kab mob clostridium genus.

Ntshav system. Kev mob ntshav qab zib (suav nrog hemolytic), eosinophilia, txo qis ntawm cov platelets thiab / lossis leukocytes, agranulocytosis kuj tseem tuaj yeem tshwm sim.

Kev tswj hwm leeg tej zaum yuav teb rau kev noj tshuaj nrog mob taub hau, kiv taub hau, ntxhov siab, pw tsaug zog, pom dab, coj tus cwj pwm tsis zoo los yog hyperactivity.

Lub siab. Qhov ntsuas cov neeg mob hepatic nce, nrog rau kev ua ntawm AsAT thiab / lossis AlAT, alkaline phosphatase thiab ntshiab bilirubin asymptomatically nce.

Daim tawv nqaij. Cov tawv nqaij tuaj yeem teb rau amoxiclav kev ua kom tsawg nrog ua pob ua xua, khaus khaus, angioedema, erythema multiforme, tshuaj lom mob epidermal necrolysis, exfoliative dermatitis, Stevens-Johnson syndrome.

Cov kab mob zis - muaj cov tsos ntawm cov ntshav hauv cov zis thiab interstitial nephritis.
Nrog lub sijhawm ntev ntawm kev siv tshuaj, kub taub hau, mob plab ntawm lub qhov ncauj ntawm lub qhov ncauj, nrog rau cov neeg mob vwm ntawm lub qhov ncauj, yuav tshwm sim.

Amoxiclav thaum cev xeeb tub

Amoxiclav rau menyuam yaus

Amoxiclav nrog angina

Nws yuav tsum nco ntsoov tias cov tshuaj tua kab mob yuav tsum tsis txhob siv rau lub sijhawm ntev, vim tias qhov no nce qhov tsis kam ntawm microflora cov kab mob rau lawv.
Ntau txog mob caj pas

Sib xyaw nrog lwm yam tshuaj

• Nws yog qhov tsis tsim nyog siv ib txhij Amoxiclav thiab kev npaj ntawm anticoagulants tsis ncaj. Qhov no tuaj yeem ua rau nce sijhawm hauv prothrombin lub sijhawm.
• Kev sib cuam tshuam ntawm Amoxiclav thiab allopurinol ua rau muaj kev pheej hmoo ntawm exanthema.
• Amoxiclav txhim kho kev puas tsuaj ntawm metatrexate.
• Koj siv tsis tau ob qho tib si amoxicillin thiab rifampicin - cov no yog cov antagonists, ua ke siv cov tshuaj tua kab mob ua kom tsis muaj zog ntawm ob qho tib si.
• Amoxiclav yuav tsum tsis txhob raug coj ua ke nrog tetracyclines lossis macrolides (cov no yog cov tshuaj tua kab mob bacteriostatic), nrog rau sulfonamides vim tias txo qis hauv cov txiaj ntsig ntawm cov tshuaj no.
• Kev noj cov Amoxiclav txo cov kev ua kom muaj txiaj ntsig zoo hauv cov ntsiav tshuaj.

Sib piv nrog lwm cov tshuaj

Dab tsi yog qhov zoo dua li amoxiclav?

Amoxiclav lossis amoxicillin?

Amoxiclav lossis Augmentin?

Amoxiclav lossis Flemoxin?

Amoxiclav lossis Sumamed?

Cawv tau zoo

Txhais thiab analogues

Cov kws kho mob tshuaj xyuas

Anna Leonidovna, kws kho mob, Vitebsk. Amoxiclav muaj txiaj ntsig ntau dua hauv kev kho mob ntawm ntau yam kab mob ua pa tsis xws li nws cov tshuaj tiv thaiv kab mob, amoxicillin. Kuv sau ntawv rau kev kawm txog 5 hnub, tom qab ntawd nws yog qhov tsim nyog yuav tsum tau coj cov tshuaj uas rov qab los kho microflora.

Veronika Pavlovna, urologist. Yawg Kryvyi Rih. Cov tshuaj no muaj cov nyhuv zoo heev rau cov kab mob hauv lub cev ntawm qhov chaw mos. Nws tsis tshua muaj kev phiv tshuaj, tib lub sijhawm kuv muab tshuaj tua kab mob, tom qab noj probiotics los kho microflora ib txwm.

Andrei Evgenievich, tus kws kho mob ENT, Polotsk. Kev siv cov tshuaj no los ntawm kev txhaj tshuaj tso cai rau koj kom sai sai qhov cuam tshuam ntawm kev mob hnyav thiab mob hnyav ntawm ENT kabmob. Cov tshuaj kho cov mob nyob hauv nruab nrab pob ntseg zoo. Ib qho ntxiv, cov neeg mob noj lub txiv qab zib tawm zoo.

Kev Ntsuam Xyuas Rau Neeg Mob

Victoria, Dnipropetrovsk. Siv raws li kws kho mob sau tseg los kho tus mob tonsillitis. Pom 5 hnub. Cov tshuaj tua kab mob pib rau hnub thib 3 mob. Tus kab mob subsided los ntawm ib feem peb. Kuv caj pas nres nres. Muaj mob raws plab, dhau li ntawm ob hnub, tom qab nws kuv pib noj cov tshuaj probiotics los kho cov microflora.

Alexandra, lub nroog Lugansk. Cov tshuaj no tau raug tshuaj los ntawm kws kho mob los kho tus mob pyelonephritis. Txoj kev kawm tau 7 hnub. Thawj 3 hnub hno - tom qab ntawd cov ntsiav tshuaj. Qhov hno no zoo dua. Txawm li cas los xij, kev txhim kho pib ncig hnub plaub. Tsis muaj kev mob tshwm sim. Puas yog qhov ncauj qhuav.

Tamara, lub nroog ntawm Boyarka. Lawv txhaj kuv cov tshuaj no rau kev kho mob kis mob rau poj niam. Nws mob heev, cov nqaij doog tseem nyob ntawm thaj chaw txhaj tshuaj. Txawm li cas los xij, tom qab ib lub lim tiam tsis muaj ib txoj kab tseem tshuav hauv lub luag nyav los ntawm cov kab mob tseem ceeb.

Amoxiclav rau menyuam yaus

Cov Ntaub Ntawv Ntxiv

Yog tias cov tshuaj siv tau ntev, nws yog ib qho tsim nyog los saib xyuas lub siab ua haujlwm ntawm lub siab, cov ntshav cov ntshav thiab cov raum ntawm tus neeg mob.Yog hais tias tus neeg mob tau kho lub raum lub siab, nws yog qhov tsim nyog yuav tau kho lub koob tshuaj lossis nce ntxiv lub sijhawm ntawm cov koob tshuaj ntawm cov tshuaj. Nws yog qhov zoo dua rau kev noj tshuaj nrog zaub mov. Thaum kis superinfection (qhov pom ntawm microflora tsis raug rau cov tshuaj no), nws yog ib qho tsim nyog yuav tau hloov cov tshuaj. Vim tias qhov ua rau hla kev tsis haum nrog cephalosporins nyob rau hauv cov neeg mob rhiab rau penicillins, nws tsis tsim nyog siv cov tshuaj tua kab mob no ua ke.

Thaum noj tshuaj, koj yuav tsum haus kua ntau hauv cov kua thiaj li zam dhau qhov tsim ntawm amoxicillin muaju hauv cov zis.

Koj yuav tsum paub tias muaj cov koob tshuaj loj heev hauv cov tshuaj tua kab mob hauv lub cev tuaj yeem ua rau muaj qhov tsis zoo rau cov ntshav qabzib (yog Benedict reagent lossis Fleming tov tau siv los txiav txim rau nws). Cov txiaj ntsig zoo dua qub nyob rau hauv qhov no yuav muab kev siv cov tshuaj tiv thaiv enzymatic nrog glucosidase.

Txij li thaum cov kev mob tshwm sim los ntawm cov leeg muaj zog thaum siv yeeb tshuaj, nws yog qhov yuav tsum ua tib zoo tsav tsheb (tsheb) lossis koom nrog kev ua si uas yuav tsum muaj kev xav ntau, kev ceev nrawm thiab kev saib xyuas.

Amoxiclav 625 hais txog cov tshuaj tua kab mob nrog kev pom dav. Nws yog cov tshuaj sib txuam. Nws nyob ntawm pawg loj ntawm penicillins.

Npe

Lub npe ntawm cov tshuaj hauv Latin yog Amoksiklav.

Amoxiclav 625 hais txog cov tshuaj tua kab mob nrog kev pom dav.

Tso cov ntaub ntawv thiab cov nyob ua ke

Tawm nyob rau hauv daim ntawv ntawm:

1. Zaj duab xis-coated ntsiav tshuaj. Cov tshuaj tseem ceeb: amoxicillin 250, 500 thiab 875 mg (muaj nyob hauv daim ntawv ntawm amoxicillin trihydrate) thiab clavulanic acid 125 mg. Cov nkauj muaj ntxiv: silicon dioxide, crospovidone, sodium croscarmellose, magnesium stearate, talc. Cov ntsiav tshuaj muaj nyob rau hauv blisters thiab lub khob ntawm cov iav dub. Ib pob ntawv ntawm cardboard muaj 1 lub raj mis lossis 1 lub hlwv (rau 15 ntsiav tshuaj) thiab cov lus qhia rau siv.
2. Hmoov rau qhov npaj cov ncua kev kawm ntawv rau qhov ncauj cov thawj coj thiab kev npaj ntawm kev daws rau kev txhaj tshuaj rau cov leeg.

Pharmacological kev txiav txim

Amoxicillin cuam tshuam ntau yam gram-negative thiab gram-zoo pathogens uas nkag siab rau penicillins. Qhov kev txiav txim yog raws ntawm kev tsocai ntawm peptidoglycan hluavtaws. Nws yog lub hauv paus ntawm cov qauv ntawm cov phab ntsa ntawm cov kab mob. Nyob rau tib lub sijhawm, lub zog ntawm cov xovtooj ntawm tes txo qis, lysis sai thiab tuag ntawm txhua tus kabmob pathogenic tshwm sim.

Amoxiclav cuam tshuam ntau yam gram-tsis zoo thiab gram-zoo pathogens.

Vim hais tias Txij li thaum amoxicillin raug pov tseg hauv kev qaug ntawm qee yam beta-lactamases, cov spectrum ntawm kev ua ntawm cov tshuaj tsis siv rau cov kab mob uas coj los ua ke lactamases.

Clavulanic acid yog ib qho muaj zog heev beta-lactamase inhibitor. Hauv nws cov qauv, nws zoo ib yam li penicillins. Hauv kev hais txog qhov no, lub spectrum ntawm kev txiav txim ntawm cov tshuaj kuj txuas ntxiv rau cov kab mob me me uas sib txuas nrog nonchromosomal beta-lactamases.

Cov Tshuaj Pharmacokinetics

Cov tshuaj yeeb dej caw yog nqus tau zoo. Qhov nqus tau zoo tshaj yuav yog koj haus cov tshuaj ua ntej noj mov. Qhov siab tshaj plaws ntawm cov tshuaj yeeb dej caw hauv cov ntshav tau pom tom qab 2-3 teev. Cov khoom siv nquag tuaj yeem pom muaj nyob hauv ntau lub plab hnyuv siab raum thiab cov ntaub so ntswg, hauv cov kua dej thiab cov kua dej synovial.

Lub peev xwm los khi rau cov ntshav protein yog qhov tsawg. Kev mob plab zom mov tshwm sim hauv lub siab. Cov tshuaj siv tawm hauv raum. Ib nrab-lub neej lub sijhawm yog li ib teev.

Ntawm cov tshuaj tua kab mob ntawm cov tshuaj Amoxiclav 625, kev tshuaj xyuas cov neeg mob thiab cov kws tshaj lij feem ntau yog cov cim. Cov tshuaj yog suav tias yog cov tshuaj tua kab mob ntau tshaj plaws thiab yog li ntawd tau txais kev lees paub dav. Vim tias qhov kev pom dav dav ntawm kev nqis tes, kev nyab xeeb ntawm kev siv hauv cov menyuam yaus thiab cov pojniam muaj menyuam, cov Amoxicillin Clavulanate yuav luag tag nrho cov kev ua haujlwm ntawm kev kho mob ua pa rau mob ua pa thiab cov kab mob genitourinary.

Cov Cai Siv Tshuaj So

Nws yog tso rau ntawm lub hwj tshuaj.

Amoxiclav ntau npaum li cas? Tus nqi nruab nrab hauv cov khw muag tshuaj yog nyob ntawm daim ntawv tso tawm:

• Nqi Amoxiclav ntsiav tshuaj 250 mg + 125 mg qhov hnyav 230 rubles rau 15 pcs. Yuav cov tshuaj tiv thaiv 500 mg + 125 mg tuaj yeem them nqi ntawm 360 - 400 rubles rau 15 pcs. Npaum li cas yog cov ntsiav tshuaj 875 mg + 125 mgnyob ntawm qhov chaw muag khoom. Qhov nruab nrab, lawv cov nqi yog 420 - 470 rubles rau 14 pcs.
• Nqi Amoxiclav Quicktab 625 mg - los ntawm 420 rubles rau 14 pcs.
• Raug tshem tawm tus nqi Amoxiclav rau menyuam yaus - 290 rubles (100 ml).
• Nqi Amoxiclav 1000 mg nyob rau hauv Ukraine (Kiev, Kharkov, thiab lwm yam) - los ntawm 200 hryvnias rau 14 daim.

Cov nyhuv Pharmacological

Kev sib xyaw ntawm amoxicillin nrog clavulanic acid yog qhov tshwj xeeb ntawm nws txoj kev. Amoxicillin thiab lwm yam tshuaj tua kab mob ntawm cov pab pawg neeg penicillin ua rau cov kab mob tuag los ntawm khi los ntawm khi lawv cov chaw. Txawm li cas los xij, feem ntau cov kab mob tau kawm rhuav tshem cov tshuaj tua kab mob no nrog cov beta-lactamase enzyme thaum siv cov tshuaj.

Clavulanic acid txo qhov kev ua haujlwm ntawm qhov enzyme, yog li cov tshuaj no muaj qhov kev pom dav dav. Nws tua tau txawm tias hom kab mob tiv taus amoxicillin. Cov tshuaj muaj cov cim ntawm cov kab mob bacteriostatic thiab bactericidal ua rau txhua hom kab mob streptococci (tshwj tsis yog methicillin-resistant leeg), echinococcus, thiab listeria.

Cov kab mob Gram-negative kuj tseem nkag rau amoxiclav:

• Bordetella
• brucella
• vaj,
• Klebsiella
• moraxella
• salmonella
• Cuam Tshuam
• shigella
• clostridium thiab lwm tus.

Tsis hais txog ntawm kev sib xyaw nrog kev noj zaub mov, cov tshuaj tau zoo rau hauv lub cev, qhov siab tshaj plaws ntawm cov tshuaj tau mus txog hauv thawj teev tom qab nkag.

Kev ntsuas rau siv

Amoxiclav yog tshuaj rau kev kis mob los ntawm kab mob rhiab ntawm cov kab mob me me, uas yog nrog cov kab mob hauv qab no:

1. Kev kis mob ntawm biliary huam (cholangitis, cholecystitis).
2. Cov pob txha thiab cov nqaij mob sib kis.
3. Kev kis mob ntawm daim tawv nqaij thiab cov nqaij mos (impetigo, phlegmon, erysipelas, qog, kab mob thib ob yog dermatoses).
4. Osteomyelitis, mob hlwb, mob sepsis thiab mob endocarditis.
5. Kev kis mob ntawm cov kabmob ENT, qis thiab sab sauv ntawm txoj hlab pa (pharyngitis, tonsillitis, sinusitis thiab otitis media) nyob rau hauv cov mob loj thiab mob ntev, pharyngeal abscess, mob ntsws, mob ntsws txham nrog superinfection, mob ntsws ntev) yog cov mob ntawm txoj hlab ntaws thiab lub plab pelvic.

Kev siv cov Amoxiclav yog qhov muaj txiaj ntsig zoo rau kev tiv thaiv kev tiv thaiv kab mob hauv kev phais thiab kev kho mob ntawm kev mob tom qab.

Cev xeeb tub thiab lactation

Amoxiclav cev xeeb tub tuaj yeem siv tau yog tias cov nyhuv xav tau tshaj qhov tsim kev puas tsuaj rau tus menyuam hauv plab. Kev siv tshuaj Amoxiclav nyob rau thaum ntxov ntawm kev xeeb tub yog qhov tsis xav tau.

2 lub hlis thiab 3 peb hlis muaj ntau dua, tab sis txawm tias lub sijhawm no kev noj tshuaj ntawm Amoxiclav thaum cev xeeb tub yuav tsum pom tseeb meej heev. Amoxiclav pub niam mis tsis txhob sau ntawv tshuaj, txij li cov tshuaj ua kom nquag plias nkag mus rau niam mis.

Cov lus qhia rau siv Amoxiclav

Cov lus qhia rau kev siv qhia tias ntsiav tshuaj Amkosiklav cov laus thiab menyuam yaus hnub nyoog 12 xyoos (lossis nrog lub cev hnyav> 40 kg) ntawm mob sib khuav me lossis mob sib kis taw 1 tab. (250 mg + 125 mg) txhua 8 teev lossis 1 daim. (500 mg + 125 mg) txhua 12 teev, yog tias kev kis mob hnyav thiab mob ntsws - 1 tab. (500 mg + 125 mg) txhua 8 teev lossis 1 daim. (875 mg + 125 mg) txhua 12 teev