Tus nqi thiab qhov sib txawv ntawm cov muaj pes tsawg leeg ntawm cov "Humalog", cov lus qhia rau kev siv, tshuaj xyuas thiab analogues ntawm cov tshuaj insulin
Yuav kom tau txais kev them nyiaj ncua ntev rau cov ntshav qab zib, ntau yam tshuaj tua kab mob insulin ntau yam. Insulin Lizpro yog qhov tseem niaj hnub thiab muaj kev tiv thaiv ultra-luv-yeeb tshuaj uas tswj cov metabolism hauv qabzib.
Cov cuab yeej no tuaj yeem qhia tau rau kev siv los ntawm cov ntshav qab zib ntawm cov hnub nyoog sib txawv. Insulin Lizpro tuaj yeem tsim kho rau cov menyuam yaus muaj ntshav qab zib.
Piv nrog luv luv ua yeeb yam insulin, Insulin Lizpro ua tau nrawm dua, vim nws qhov nqus tau siab.
Pharmacological kev ua thiab kev ntsuas
Lizpro biphasic insulin yog tsim los siv cov thev naus laus zis DNA thev naus laus zis. Muaj kev cuam tshuam nrog cov receptor ntawm cytoplasmic membrane ntawm cov hlwb, ib qho insulin-receptor complex yog tsim, uas tsim kho cov txheej txheem hauv cov hlwb, suav nrog cov synthesis ntawm cov enzymes tseem ceeb.
Qhov kev txo qis hauv cov ntsiab lus ntawm cov piam thaj hauv cov ntshav tau piav qhia los ntawm kev nce ntxiv hauv nws qhov kev ua haujlwm hauv intracellular, nrog rau kev nce ntxiv thiab nqus cov hlwb. Cov piam thaj tuaj yeem txo qis vim qhov qis dua ntawm nws tus kheej los ntawm daim siab los yog daim siab ntawm glycogenogenesis thiab lipogenesis.
Lyspro insulin yog cov DNA tso tawm cov khoom sib txawv ntawm qhov rov qab sib txuas ntawm lysine thiab proline amino acid seem ntawm 28 thiab 29 txoj haujlwm ntawm insulin B saw. Cov tshuaj muaj 75% cov tshuaj tiv thaiv kev ncua thiab 25% lyspro insulin.
Cov tshuaj muaj cov teebmeem anabolic thiab kev tswj ntawm cov metabolism hauv qabzib. Hauv cov ntaub so ntswg (tshwj tsis yog lub hlwb cov ntaub so ntswg), kev hloov pauv ntawm cov piam thaj thiab amino acids mus rau lub cell ceev, uas ua rau muaj kev tsim cov glycogen los ntawm cov piam thaj hauv lub siab.
Cov tshuaj no txawv ntawm cov tshuaj insulins hauv kev ua haujlwm sai ntawm lub cev thiab qhov tsawg kawg ntawm kev phiv.
Cov tshuaj pib ua yeeb yam tom qab 15 feeb, vim nws lub siab nqus. Yog li, nws tuaj yeem siv sijhawm li 10-15 feeb ua ntej noj mov. Cov tshuaj insulin tsis tu ncua yog muab rau hauv tsis pub tsawg tshaj ib nrab ib teev.
Tus nqi ntawm kev nqus tau cuam tshuam los ntawm qhov chaw txhaj tshuaj thiab lwm yam. Lub ncov ntawm kev nqis tes ua tau pom nyob hauv thaj tsam 0.5 - 2.5 teev. Cov tshuaj Insulin Lizpro ua rau plaub teev.
Lizpro insulin hloov yog qhia rau cov neeg muaj ntshav qab zib hom mob ntshav qab zib mellitus, tshwj xeeb tshaj yog hais tias tsis nkag rau lwm yam tshuaj insulin. Ntxiv rau qhov no, nws yog siv nyob rau hauv xws li:
- postprandial hyperglycemia,
- subcutaneous insulin kuj nyob rau hauv daim ntawv mob.
Cov tshuaj kuj tseem siv rau hom 2 mob ntshav qab zib mellitus nrog cov tshuaj tiv thaiv hypoglycemic qhov ncauj tshuaj.
Lizpro insulin tuaj yeem kho nyob rau hauv kev sib deev ib txwm muaj.
Insulin Apidra Solostar: cov lus qhia rau kev siv ntawm kev daws
Apidra Solostar yog cov tshuaj insulin ua luv luv, uas yog npaj rau kev tswj glycemic hauv insulin-tiv thaiv kev mob ntshav qab zib.
Nws yog tshuaj rau cov neeg laus thiab menyuam yaus txij thaum muaj rau xyoo los ntawm kev mob ntshav qab zib, yog tias tsim nyog, kev kho tshuaj insulin.
Kev Sau thiab tso cov foos
Hauv 1 milliliter ntawm Apidra Solostar tov tsuas muaj cov tshuaj ua kom nquag plias - insulin glulisin hauv ib koob tshuaj ntawm 100 daim duab PIECES. Tsis tas li, cov tshuaj muaj:
- Hydroskide thiab Sodium Chloride
- Npaj ua dej
- Metacresol
- Polysobat
- Trometamol
- Hydrochloric acid.
Cov tshuaj dej hauv cov kua dej yog cov dej ntshiab, tsis muaj kua, muaj nyob hauv 3 ml vials. Cov ntim muaj nrog 1 lossis 5 lub raj nrog ib xaum xaum xaum.
Kho thaj chaw
Cov tshuaj insulin glulisin muaj nyob hauv Apidra yog qhov tso tawm ua ntej ntawm cov tshuaj insulin ntuj tsim hauv tib neeg lub cev. Glulisin ua ntau nrawm dua thiab yog tus tsim lub sijhawm luv luv piv nrog cov tshuaj insulin.
Raws li kev ua haujlwm ntawm insulin glulisin, pom maj mam hloov ntawm cov metabolism hauv qabzib. Nrog rau qhov txo qis hauv cov piam thaj, qhov kev txhawb nqa ntawm nws txoj kev nqus ncaj qha los ntawm cov ntaub so ntswg peripheral, inhibition of glucose synthesis hauv daim siab hlwb raug kaw.
Cov tshuaj insulin inhibits cov txheej txheem lipolysis tshwm sim hauv adipocytes, nrog rau cov proteolysis. Nyob rau tib lub sijhawm, protein synthesis yog qhov nce.
Raws li kev tshawb fawb ntau nrog kev koom tes ntawm cov neeg mob ntshav qab zib, nrog rau cov neeg mob noj qab haus huv, cov txiaj ntsig hauv qab no tau txais: nrog subcutaneous kev tswj hwm ntawm Apidra, sai li sai tau ntawm insulin raug pom nrog lub sijhawm luv dua li cov kua dej ntuj.
Tom qab qhia txog ntawm glulisin hauv qab daim tawv nqaij, nws cov nyhuv tshwm sim tom qab 10-20 feeb. Tab sis thaum txhaj mus rau hauv cov hlab ntsha, cov ntshav qabzib qes yuav poob qis ib yam nkaus li tom qab kev qhia tawm ntawm insulin ntuj. 1 ntu ntawm insulin glulisin yog yam ntxwv yuav luag zoo li qub hauv qab zib-txo cov yam ntxwv raws li 1 chav ntawm ntuj insulin.
Hauv cov neeg mob nrog pathologies ntawm lub raum, qhov kev xav tau rau cov kua dej yog feem ntau txo qis.
Apidra Solostar: cov lus qhia rau kev siv
Kev tswj hwm ntawm Apidra yuav tsum tau nqa tawm ua ntej noj mov lossis tam sim ntawd.
Cov tshuaj insulin yuav tsum siv raws li cov tshuaj noj uas tiv thaiv kab mob ua ke nrog cov tshuaj insulin, uas pom los ntawm qhov nruab nrab lub sijhawm ntev los yog siv cov insulin ntev. Tej zaum muaj kev siv tshuaj nrog hypoglycemic rau kev tswj hwm qhov ncauj.
Kev xaiv ntawm cov tshuaj ntau npaum li cas yog nqa los ntawm endocrinologist.
Apidra Taw qhia
Cov lus qhia ntawm cov kua dej muaj cov kua tshuaj yog nqa tawm los ntawm kev txhaj tshuaj los yog infusion siv lub twj tso kua mis tshwj xeeb.
Kev txhaj tshuaj subcutaneous yog nqa tawm hauv plab phab ntsa (ncaj qha nws sab pem hauv ntej), hauv cheeb tsam femoral lossis xub pwg. Txoj kev lis ntshav ntawm cov tshuaj yog nqa tawm hauv plab phab ntsa. Cov chaw ntawm Txoj kev lis ntshav thiab txhaj tshuaj yuav tsum tau hloov tas li.
Kev siv tus cwj mem uas qhwv siv
Ua ntej kev qhia paub ntawm Apidra, koob txhaj tshuaj yuav tsum tau sov me ntsis ntawm chav sov (kwv yees li 1-2 teev).
Txoj kev hno koob tshiab txuas rau cov tshuaj insulin syringe cwj mem, tom qab ntawd koj yuav tsum ua qhov ntsuas kev nyab xeeb yooj yim. Tom qab ntawd, qhov ntsuas pom “0” yuav pom ntawm lub qhov rai ntim tshuaj ntawm lub ntsej muag xaum xim. Tom qab ntawd qhov tsim nyog koob tshuaj tau tsim muaj. Qhov tsawg kawg nkaus tus nqi ntawm cov tshuaj tso cai yog 1 chav tsev, thiab qhov siab tshaj plaws yog 80 units. Yog tias xav tias yuav tsum tau noj ntau dhau, ntau txoj kev txhaj tshuaj.
Thaum lub sijhawm txhaj, rab koob, uas ntsia rau ntawm rab koob txhaj tshuaj, yuav xav tau maj mam nkag hauv qab daim tawv nqaij. Lub khawm rau ntawm rab koob xaum yuav raug nias, nws yuav tsum nyob twj ywm rau hauv txoj haujlwm no tam sim ntawd kom txog thaum lub sijhawm ntawm rho tawm. Qhov no ua kom qhov kev taw qhia ntawm qhov xav tau ntau npaum li cas ntawm ib qho tshuaj insulin-muaj.
Tom qab txhaj koob, rab koob raug tshem tawm thiab pov tseg. Yog li, nws yuav muaj peev xwm tiv thaiv tus kab mob ntawm cov insulin koob txhaj. Yav tom ntej, kua cwj mem yuav tsum tau kaw nrog lub hau.
Cov tshuaj tuaj yeem raug teem tseg rau cov poj niam cev xeeb tub thiab lactating.
Cov Kev Tsis Txaus Ntseeg thiab Kev Ceev Faj
Nqe: txij li 421 txog 2532 rub.
Cov tshuaj insulin-muaj cov tshuaj Apidra Solostar tsis yog siv rau qhov tshwm sim ntawm kev mob ntshav qab zib thiab ua rau muaj kev cuam tshuam ntau ntxiv rau cov tshuaj ntawm cov tshuaj.
Thaum siv cov tshuaj insulin-tshuaj los ntawm lwm lub chaw tsim khoom, yuav tsum ua tib zoo tswj kev siv tshuaj tiv thaiv kab mob kev nkeeg los ntawm cov kws kho mob koom nrog, vim tias yuav tsum tau kho qhov kev noj tshuaj tsis tuaj yeem txiav tawm. Koj yuav tsum tau pauv pauv cov phiaj xwm ntawm kev kho hypoglycemic ntawm cov tshuaj rau kev tswj hwm qhov ncauj.
Kev ua tiav ntawm kev siv tshuaj tiv thaiv kab mob siab lossis siv cov tshuaj insulin ntau kawg, tshwj xeeb yog cov neeg mob ntshav qab zib, tuaj yeem ua rau ketoacidosis mob ntshav qab zib, ua rau mob ntshav qab zib tsawg, uas ua rau muaj kev phom sij rau lub neej.
Lub sijhawm nyob ntawm lub sijhawm rau qhov tshwm sim ntawm hypoglycemia yog ncaj qha ntsig txog tus nqi ntawm kev txhim kho ntawm cov tshuaj tiv thaiv hypoglycemic los ntawm cov tshuaj siv, nws tuaj yeem hloov nrog kev kho ntawm cov tshuaj tiv thaiv kab mob siab.
Qee yam ua tau tuaj yeem txo qhov hnyav ntawm cov ntshav qog ntshav qis, lawv suav nrog:
- Mob ntshav qab zib ntev
- Kev kho mob insulin ntau
- Kev txhim kho rau cov ntshav qab zib mob neuropathy
- Kev siv ntau ntawm cov tshuaj (piv txwv li, β-blockers).
Kev hloov pauv ntawm koob tshuaj insulin Apidra Solostar yog ua tiav nrog kev nce hauv lub cev lossis kev hloov pauv ntawm cov zaub mov noj txhua hnub.
Cov kev tawm dag zog lub cev tam sim ntawd tom qab noj mov, qhov yuav ua rau muaj ntshav qab zib tsawg zuj zus. Cov tshuaj tua kab mob luv luv ua haujlwm tuaj yeem ua rau qhov pib ntawm lub qog ntshav qab zib.
Qhov tsis pom txog hypo- thiab hypoglycemic cov tsos mob tshwm sim ua rau muaj qhov tshwm sim ntawm tus neeg mob ntshav qab zib ua pa, coma, lossis ua rau tuag.
Nrog rau kev hloov pauv ntawm lub siab lub ntsws, kev txhim kho ntawm qee yam kab mob, nws yuav tsim nyog kho qhov tshuaj noj ib koob tshuaj insulin.
Thaum ua haujlwm nrog cov txheej txheem meej, tsav tsheb, qhov kev pheej hmoo ntawm kev txhim kho hypo- thiab hyperglycemia nce, yog li kev saib xyuas tshwj xeeb yuav tsum tau ua.
Hla kev sib txuam yeeb tshuaj
Thaum noj qee cov tshuaj, ib qho cuam tshuam ntawm cov metabolism hauv qabzib yuav raug sau cia, hauv kev sib txuas nrog qhov no, yuav tsum kho cov tshuaj ntau ntau ntawm glulisin thiab tswj nruj kev coj ua ntawm cov tshuaj tiv thaiv kab mob siab.
Ntawm cov tshuaj uas ua rau cov hypoglycemic nyhuv ntawm glulisin suav nrog:
- Cov tshuaj tiv thaiv ntawm ib qho tshwj xeeb angiotensin-hloov pauv enzyme, monoamine oxidase
- Pentoxifylline
- Kuaj Tshuaj
- Txhais tau tias raws li cov tshuaj sulfonamide antimicrobial tus sawv cev
- Disopyramides
- Kev siv tshuaj hypoglycemic rau kev siv lub qhov ncauj
- Fluoxetine
- Cov ntsev
- Propoxyphene.
Ib tug xov tooj ntawm cov tshuaj raug faib uas txo qis hypoglycemic nyhuv ntawm ib qho tshuaj insulin-muaj:
- Isoniazid
- Somatropin
- Danazole
- Qee qhov sympathomimetics
- Estrogen-progestin tshuaj
- COC
- Diazoxide
- Protease inhibitors
- Cov thyroid hormones
- Cov tshuaj tiv thaiv kev puas hlwb
- GKS
- Phenothiazine Derivatives
- Cov tshuaj diuretic.
Nws yog tsim nyog sau cia tias β-adrenergic thaiv cov kab mob, cov tshuaj ethanol thiab muaj lithium uas muaj cov tshuaj, clonidine muaj peev xwm ua rau ob leeg nce thiab txo cov nyhuv hypoglycemic ntawm Apidra.
Thaum siv cov reserpine, β-adrenoblockers, clonidine, thiab guanethidine, cov cim ntawm hypoglycemia yuav tsis muaj zog lossis tsis tuaj.
Txij li tsis muaj cov ntaub ntawv hais txog kev siv tshuaj ntawm gluzilin, tsis txhob sib xyaw nws nrog lwm yam tshuaj, lub ntuj insulin isofan yog kev zam.
Kev siv lub tshuab nqus ntshav los tswj Apidra, sib xyaw cov kua dej muaj tshuaj nrog lwm cov tshuaj yuav tsum tsis txhob.
Phiv thiab haus tshaj
Feem ntau, cov neeg mob ntshav qab zib yuav pib mob txaus ntshai xws li hypoglycemia.
Muaj qee kis, pom tawm pob ntawm daim tawv thiab qhov pom ntawm lub ntsej muag o tuaj.
Kev tshwm sim ntawm lipodystrophy yog tias tsis ua raws li cov kev cai ntawm kev kho mob tshuaj tiv thaiv kab mob tsis zoo.
Lwm cov kev qhia ua xua:
- Dermatitis ntawm kev tsis haum genesis, tawm pob los ntawm hom urticaria, ua tsis taus pa
- Zoo nkaus ntawm cov hauv siab hauv siab (zoo li tsawg).
Nws tsim nyog sau cia tias cov tshuaj tiv thaiv los ntawm cov tshuaj tiv thaiv kab mob (kev tiv thaiv ua kom tsis haum) tuaj yeem theem nyob rau hnub tom qab txhaj tshuaj. Qee qhov xwm txheej, qhov tshwm sim tsis zoo yog los ntawm kev tsis raug insulin, tab sis los ntawm kev ua kom tawv nqaij ua ntej los ntawm kev kho mob ua ntej nrog cov tshuaj tiv thaiv kab mob lossis vim tias kev txhaj tshuaj tsis haum.
Thaum kuaj pom ib qho kev phiv tshuaj dav dav, qhov kev pheej hmoo yuav tuag yog qhov siab. Yog li, ntawm qhov tshwm sim me ntsis ntawm cov kev mob tshwm sim, koj yuav tsum tau sab laj ib tus kws kho mob.
Nrog kev qhia txog kev siv tshuaj ntau tshaj ntawm Apidra, kev mob ntshav qab zib tsawg tuaj yeem tsim ua ob hom me thiab hnyav. Hauv qhov no, nws yog qhov yuav tsum tau ua kev kho mob:
- Me - Cov zaub mov lossis dej qab zib uas muaj suab thaj
- Daim foos hnyav heev (tsis nco qab lawm lub xeev) - rau kev tso tseg, 1 ml ntawm cov tshuaj Glucagon tau txais kev tso cai hauv qab daim tawv nqaij los yog cov leeg nqaij, thaum tsis muaj kev tawm tsam rau Glucagon, cov tshuaj pleev ntshav qabzib yog ua tau.
Tom qab tus neeg mob rov qab nco qab, nws yuav tsim nyog los muab nws nrog cov pluas mov noj hauv carbohydrates. Tom qab, kev saib xyuas tus neeg mob kom zoo los ntawm tus kws kho mob tau pom zoo.
Ely Lilly thiab Tuam Txhab, Fab Kis
Nqi los ntawm 1602 txog 2195 rub.
Humalogue yog ib tus neeg sawv cev uas nthuav tawm lub suab hypoglycemic nyhuv. Cov tshuaj Humalog muaj cov tshuaj insulin lyspro. Raws li lub zog ntawm cov tshuaj, nws yuav muaj peev xwm los tswj cov metabolism hauv cov piam thaj thiab txhim kho cov protein ua ke. Cov tshuaj yeeb yaj kiab tau tsim tawm hauv kev sib tov thiab ncua kev kawm.
Pros:
- Kev Siv Tau
- Qhov pib ntawm kev cuam tshuam hypoglycemic sai
- Kev phiv loj heev tsis zoo li yuav loj hlob tuaj.
Cons:
- Tsis txhob siv yog tias xav tias hypoglycemia.
- Muaj nqi
- Tej zaum yuav ua rau tawm hws.
Humulin NPH
Eli Lilly East S.A., Switzerland
Nqi los ntawm 148 txog 1305 rub.
Humulin NPH - ib yam tshuaj nrog cov tshuaj insulin-isophan nquag, yog siv hauv cov ntshav qab zib kom tswj tau glycemia. Humulin NPH yog tsim nyob rau hauv daim ntawv ntawm kev daws hauv cov roj cartridges uas siv rau cov kua roj ntsha syringe.
Pros:
- Yuav tau raug muab rau xeeb tub
- Siv rau thawj kuaj mob ntshav qab zib
- Kev siv tshuaj tua kab mob ntev ntev yuav raug tso cai.
Cons:
- Tej zaum yuav ua rau khaus.
- Ntawm keeb kwm ntawm kev kho mob, lub plawv dhia tuaj yeem kuaj mob
- Nws yog tso tawm los ntawm cov tshuaj noj.
Novo Nordic, Denmark
Nqi los ntawm 344 txog 1116 rubles.
LS muaj cov tshuaj insulin luv luv. Nws yog tshuaj rau ntshav qab zib thaum tsis muaj glycemic tswj los ntawm lwm cov tshuaj. Nyob hauv txoj cai ntawm Actrapid, cov chav kawm raug tso tawm vim yog tshwj xeeb kev txhawb ntawm cAMP biosynthesis thiab kev nkag mus sai rau cov leeg nqaij. Cov tshuaj nquag yog solulin insulin. Cov tshuaj yeeb yaj kiab tau tsim tawm los ntawm kev sib tov.
Pros:
- Tus nqi qis
- Ceev ceev hauv cov ntshav qab zib
- Nws tuaj yeem siv nrog cov insulin ntev.
Cons:
- Qhov pom ntawm cov cim ntawm lipodystrophy tsis kav
- Quincke edema tuaj yeem tsim kho
- Nrog rau kev ua kom lub cev ntau ntxiv, yuav tsum muaj kev hloov kho koob tshuaj.
Kev siv cov insulin Humalog Lizpro
Lizpro insulin yog ib qho tshuaj ntawm tib neeg cov tshuaj insulin. Kev ua tseem ceeb ntawm cov cuab yeej no yog kev cai ntawm cov kua nplaum tsim thiab ua. Tib lub sijhawm, nws yog Lizpro insulin uas yog tus cwj pwm anabolic, uas yog, nws pab txhawb rau kev loj hlob ntawm cov leeg mob.
Hauv kev sib piv nrog luv luv ua yeeb yam npaj rau insulin, insulin Lizpro (Humalog) cov kws tshaj lij soj ntsuam qhov pib sai thiab ua tiav ntawm cov ua tiav.
Nws raug nquahu kom koj them sai sai rau yam dab tsi ntawm cov yam ntxwv ntawm kev tso tawm, siv cov cuab yeej no - txhua qhov no yuav pab cov neeg mob ntshav qab zib siv cov tshuaj muaj tseeb.
Cov lus sib xyaw thiab daim ntawv ntawm cov tshuaj
Cov tshuaj Insulin Lizpro yog cov tshuaj tsis huv thiab meej, uas yog tsim tshwj xeeb rau kev qhia txog ntawm ob leeg txoj leeg thiab subcutaneous. Nws yuav tsum tau yug los hauv lub siab tias Humalog suav nrog lub ntsiab insulin Lizpro hauv qhov nyiaj ntawm 100 IU. Ib qho ntxiv, peb yuav tsum tsis txhob hnov qab txog qee feem kev pabcuam, tshwj xeeb:
- glycerol (glycerin),
- zinc oxide
- metacresol
- sodium hydrogen phosphate heptahydrate,
- Cov kua 10% hydrochloric acid tov thiab / lossis 10% sodium hydroxide tov,
- dej.
Tshwj xeeb mloog tsim nyog ntim ntawm insulin Lizpro (Humalog). Peb tab tom tham txog tsib peb-ml roj cartridges hauv hlwv lossis tsib peb-ml roj cartridges hauv QuickPen koob txhaj tshuaj. Txhawm rau kom nkag siab zoo dua lub algorithm ntawm cov nyhuv ntawm cov tshuaj tiv thaiv hormonal, nws pom zoo kom them sai sai rau cov ntsiab cai ntawm nws cov nyhuv pharmacological.
Dab tsi koj yuav tsum paub txog qhov kev txiav txim ntawm pharmacological?
Lizpro muaj peev xwm muaj kev cuam tshuam loj rau cov kev cai ntawm cov piam thaj. Ntxiv rau, qhov tshuaj tiv thaiv hormonal no tus cwj pwm qee cov cim anabolic. Nws yog tus cwj pwm los ntawm kev muaj peev xwm ua kom nrawm nrawm ntawm kev hloov pauv ntawm cov piam thaj thiab amino acids mus rau kev sib xyaw ntawm tes.
Ntxiv rau, nws yog qhov kev tiv thaiv hormonal uas muaj txiaj ntsig tseem ceeb rau kev tsim cov glycogen los ntawm cov piam thaj hauv lub siab. Nws kuj ua rau nws muaj peev xwm txhawm rau gluconeogenesis thiab txhawb kev hloov pauv ntawm cov piam thaj ntau dhau mus ua rog.
Qhov tshuaj insulin no yog sib npaug rau tib neeg cov tshuaj insulin (muaj cov hniav sib kis tib yam).
Cov kws tshaj lij kos xim rau qhov tseeb tias qhov pib ntawm kev ua yog nrawm dua li lwm hom insulin ntawm tib neeg.
Tsis tas li ntawd, qhov muaj pes tsawg leeg yog tus cwj pwm los ntawm ib qho kev txhim kho ua ntej ntawm lub ncov ntawm kev sib kis thiab lub sijhawm luv luv lub sijhawm xav tau rau kev ua haujlwm hypoglycemic. Kev pib kis sai (15 feeb tom qab txhaj tshuaj) cuam tshuam nrog kev nqus sai.
Nws yog qhov no uas, vim li ntawd, ua rau nws muaj peev xwm qhia nws tam sim ntawd ua ntej noj zaub mov. Thaum tib neeg cov insulin pom zoo kom siv tsis pub ntau tshaj 30 feeb ua ntej noj mov.
Qhov chaw txhaj tshuaj muaj qhov tshwj xeeb tshaj plaws rau ntawm tus nqi ntawm kev nqus, nrog rau thaum pib ntawm nws cov nyhuv. Yog li ntawd koj yuav tsum ua tib zoo saib xyuas cov haujlwm thiab sab laj nrog tus kws tshaj lij. Ntawm lwm yam, ua ntej koj pib siv cov tshuaj insulin, Lizpro feem ntau yuav paub txog cov cim tseem ceeb rau kev siv. Cov cai tswjfwm kev siv tshuaj insulin Tresiba Kev hais txog cov cim tseem ceeb rau kev siv, nws yog thawj zaug ntawm txhua qhov kev pom zoo ua tib zoo mloog rau yam 1 mob ntshav qab zib mellitus. Ntxiv mus, qhov no yog qhov tsim nyog nyob rau hauv ib qho xwm txheej cuam tshuam nrog kev tsis txaus siab rau lwm hom kev tiv thaiv hormonal. Qhov qhia ntxiv tom ntej yog daim ntawv tom qab ntawm hyperglycemia uas tsis tuaj yeem kho los ntawm lwm hom tshuaj insulin. Lwm qhov ntsuas tseem ceeb yuav tsum tau txiav txim siab raws li hom 2 mob ntshav qab zib mellitus, uas yog thaum nws tsis tuaj yeem siv ib qho ncauj qab zib-txo cov tshuaj noj cov qauv. Tsis tas li ntawd, ib qho yuav tsum tsis txhob hnov qab tias Lizpro insulin yog qhov yuav tsum tau ua thaum lwm hom insulin tsis tuaj yeem raug nqus tau. Thiab thaum kawg, lwm qhov taw qhia yog lub sijhawm ua haujlwm thiab sib cuam tshuam (sib koom nrog kev sib koom tes) pathological kev mob hauv cov neeg mob ntshav qab zib. Tus nqi pes tsawg ntawm Lizpro insulin txhaj yog xav pom zoo raws li kev suav glycemic. Hais txog qhov no, nws raug nquahu kom xyuam xim rau qhov tseeb tias:Lub cim tseem ceeb rau kev siv
Tsuas tshuaj thiab tswj hwm
Cov neeg mob uas lub raum lossis hepatic tsis txaus yuav muaj qhov nce siab ntawm cov ntshav insulin, tab sis nrog kev xav txo.
Tag nrho cov no yuav xav tau tas mus li saib xyuas qhov piv ntawm glycemia, nrog rau kev kho lub sijhawm ntawm cov tshuaj ntawm cov tshuaj tiv thaiv hormonal.
Txhawm rau hauv lub siab peculiarities ntawm kev siv thiab ntau npaum li cas, ib qho yuav tsum tsis txhob hnov qab txog contraindications thiab qee qhov kev mob tshwm sim, uas yog qhov tseem ceeb heev rau txhua tus mob ntshav qab zib.
Cov kev thaiv tsis zoo thiab cov tshwm sim
Cov coj contraindications yuav tsum raug xam tias yog ib tus neeg tsis kam txais, muaj cov tshuaj insulinomas hauv tib neeg, zoo li ua rau ntshav qab zib.
Txawm li cas los xij, qhov no nyob deb ntawm tag nrho, vim tias nws yog qhov yuav tsum tau nco ntsoov txog kev nyiam ntawm qee cov kev mob tshwm sim. Tham txog qhov no, lawv tau them rau qee yam kev qhia ua xua. Cov no suav nrog urticaria, kev txhim kho ntawm cov mob angioedema, uas yog nrog ua npaws, ua tsis taus pa, txo ntshav siab.
Lwm yam tsis muaj qhov tshwm sim tsawg dua yog kev cuam tshuam ib ntus uas ua rau lub cev tsis muaj zog, kev txhim kho hypoglycemia lossis tseem mob ntshav qab zib, tsis zoo li ntxiv rau lipodystrophy. Hauv feem ntau ntawm cov teeb meem, qhov no yuav zam tau yog tias txhua qhov kev pom zoo ntawm cov kws tshaj lij tau ua raws, thiab tseem nco ntsoov yuav ua li cas siv cov tshuaj tiv thaiv hormonal.
Npaum li cas yog overdose ntawm cov tshuaj insulin?
Kev tshaj ntawm insulin Lizpro (Humalog) tau tshaj tawm cov kev qhia. Ua ntej tshaj plaws, peb tab tom tham txog kev tawm hws, hws tsis sib xws, tachycardia thiab tshee tshee. Peb yuav tsum tsis txhob hnov qab tias qhov pom ntawm kev xav ntawm kev tshaib plab, kev ntxhov siab yog qhov yuav tshwm sim.
Qee qhov xwm txheej, tus neeg muaj teeb meem cuam tshuam nrog kev pom thiab qee qhov kev sim kho lub cev ua haujlwm.
Muab qhov txaus ntshai ntawm tus mob no, nws raug nquahu kom saib xyuas yuav ua li cas tiv nrog cov cim ntawm kev haus ntshav qab zib ntau dhau.
Yog li, hais txog kev kho, nws yuav tsum nco ntsoov tias thaum tus neeg mob nyob rau hauv lub xeev ntawm kev nco qab, kev txhaj tshuaj ntawm Dextrose yuav tsum. Kuj tseem yuav muaj kev xav kom tswj cov kab mob glucagon los yog hypertonic dextrose.
Qhov tsim ntawm hypoglycemic coma nyob rau hauv tus neeg mob yuav cuam tshuam txog kev siv tshuaj lub dav hlau siv cov tshuaj Dextrose. Qhov no yuav tsum tau ua kom tiav ua ntej tus neeg mob tawm hauv lub xeev tsis xeev.
Txhawm rau kom nkag siab zoo dua seb cov tshuaj siv li cas, nws yog ib qho tsim nyog yuav tsum coj mus rau hauv nws qhov kev cuam tshuam nrog lwm cov tshuaj hormonal thiab tshuaj.
Sib xyaw nrog lwm cov kev txhais tau tias
Ceeb toom tag nrho cov nta thiab ntsuas ntawm kev sib raug zoo nrog lwm cov cuab yeej, cov kws tshaj lij pom zoo kom them sai sai rau cov nuances xws li:
- tsis muaj kev sib raug zoo nrog lwm cov kev tsim cov tshuaj,
- hypoglycemic algorithm ntawm cov tshuaj insulin yuav ua kom zoo dua los ntawm sulfonamides, MAO inhibitors, carbonic anhydrase. Ketoconazole, clofibrate thiab ntau lwm yam tshuaj kuj tseem yuav muaj cov nyhuv zoo sib xws.
- cov tebchaw xws li glucagon, tshuaj tiv thaiv sab hauv, estrogens, nicotine thiab lwm yam sib xyaw ua rau lub zog tsis muaj zog ntawm kev sib kis. Tias yog vim li cas nws yuav yog qhov tseem ceeb heev rau sab laj nrog tus kws tshaj lij ua ntej,
- hypoglycemic cov nyhuv ntawm cov tshuaj tiv thaiv hormonal tuaj yeem ua kom tsis muaj zog lossis ntxiv dag zog rau cov tebchaw xws li beta-blockers, reserpine, Pentamidine thiab txawm tias Octreotide.
Ntxiv mus, Kuv xav nco ntsoov qee cov lus qhia tshwj xeeb uas tau pom zoo kom xav txog ua ntej koj pib siv Lizpro insulin (Humalog).
Dab tsi yog cov lus qhia tshwj xeeb rau kev qhia cov qauv?
Yuav tsum ua raws li cov kev cai siv nruj heev. Thaum hloov cov ntshav qab zib rau insulin Lizpro nrog cov tshuaj tiv thaiv hormonal ntawm hom nrawm kis, kev hloov pauv ntau npaum.
Yog tias cov koob tshuaj hauv 24 teev rau tus neeg mob tau ntau dua 100 units, ces qhov hloov ntawm ib hom tshuaj tiv thaiv kab mob mus rau lwm qhov zoo dua yog nqa tawm hauv tsev kho mob.
Kev xav tau cov tshuaj insulin ntxiv nce nrog ntau yam kab mob sib kis, kev ntxhov siab, kev nce siab ntawm kev noj haus ntawm carbohydrates hauv kev noj zaub mov noj thiab lwm yam xwm txheej uas koj yuav tsum tau sab laj nrog kws kho mob.
Qhov xav tau rau qhov tshuaj tiv thaiv hormonal poob qis nrog lub raum lossis hepatic tsis txaus, ib qho kev txo qis ntawm qhov feem ntawm carbohydrates hauv kev noj zaub mov noj thiab cov cim kev nce ntawm kev ua si. Qhov ntxim nyiam ntawm kev tsim cov qog ntshav ntshav ua rau lub zog hnyav dua li feem ntau ntawm cov ntshav qab zib kom tsav tsheb, nrog rau kev tswj ntau yam.
Nws yog qhov tsim nyog uas cov neeg mob ntshav qab zib tuaj yeem tso tseg me ntsis ntawm cov ntshav qabzib vim lawv tus kheej kev siv zog, yog tias lawv noj qee qhov piam thaj lossis siv cov khoom noj uas muaj cov khoom noj tseem ceeb ntawm carbohydrates. Nws yog ib qho tseem ceeb tau hais qhia rau cov kws tshaj lij ntawm cov neeg tuaj hloov pauv hypoglycemia, uas yuav qhia yuav ua li cas cov koob tshuaj yuav tsum tau hloov.
Insulin Lantus: cov lus qhia, tus nqi, tshuaj xyuas cov neeg mob ntshav qab zib
Lantus yog ib qho ntawm thawj qhov tsis muaj kab zauv ntawm tib neeg cov tshuaj insulin. Tau los ntawm kev hloov cov amino acid asparagine nrog glycine ntawm txoj hauj lwm 21st ntawm txoj saw A thiab ntxiv ob lub arginine amino acids hauv cov saw B mus rau lub davhlau ya nyob twg amino acid.
Cov tshuaj no yog tsim los ntawm kev lag luam tshuaj Fabkis loj - Sanofi-Aventis. Hauv qhov kev tshawb fawb ntau, nws tau ua pov thawj tias insulin Lantus tsis tsuas yog txo cov kev mob ntshav qab zib tsawg dua piv nrog cov tshuaj NPH, tab sis tseem txhim kho cov metabolism hauv metabolism.
Hauv qab no yog cov lus qhia luv luv rau kev siv thiab tshuaj xyuas cov neeg mob ntshav qab zib.
Cov tshuaj nquag ntawm Lantus yog cov tshuaj insulin glargine. Nws kis tau los ntawm kev rov ua dua caj ces siv k-12 leeg kab ntawm cov kab mob Escherichia coli. Hauv qhov nruab nrab nruab nrab, nws yog me ntsis soluble, nyob rau hauv nruab nrab acidic nws yaj nrog kev tsim ntawm microprecipitate, uas tas li thiab maj mam tso cov kua dej. Vim tias qhov no, Lantus tau muaj ib cov profile ua haujlwm ntev txog 24 teev.
Lub ntsiab pharmacological lub zog:
- Qeeb qeeb adsorption thiab kev txiav txim siab tsis kawg hauv 24 teev.
- Kev txhawb nqa ntawm proteolysis thiab lipolysis hauv adipocytes.
- Cov nquag tivthaiv khi rau cov tshuaj insulin 5-8 zaug ntau dua.
- Cov kev cai ntawm cov piam thaj hauv cov ntshav, kev txwv tsis pub muaj cov kua nplaum tsim tawm hauv lub siab.
Hauv 1 ml Lantus Solostar muaj:
- 3.6378 mg ntawm insulin glargine (hauv 100 IU ntawm tib neeg cov tshuaj insulin),
- 85% glycerol
- dej rau kev txhaj tshuaj
- hydrochloric concentrated acid,
- m-cresol thiab sodium hydroxide.
Kev cuam tshuam nrog lwm yam tshuaj
Muaj cov tshuaj uas cuam tshuam rau cov metabolism hauv cov metabolism, thaum nce los yog txo qis yuav tsum muaj cov insulin.
Txo cov piam thaj: cov tshuaj tiv thaiv kab mob hauv lub cev, sulfonamides, ACE inhibitors, salicylates, angioprotectors, monoamine oxidase inhibitors, antiarrhythmic dysopyramides, narcotic analgesics.
Qab zib kom ntau: cov thyroid hormones, diuretics, sympathomimetics, tshuaj tiv thaiv qhov ncauj, phenothiazine derivatives, protease inhibitors.
Qee yam tshuaj muaj ob qho ua kom tsis pom kev thiab qhov ua tsis zoo. Cov no suav nrog:
- beta blockers thiab ntsev lithium,
- cawv
- clonidine (antihypertensive tshuaj).
Kev Hloov mus rau Lantus los ntawm lwm yam insulin
Yog hais tias tus mob ntshav qab zib tau siv cov tshuaj insulins-nruab nrab, tom qab ntawd thaum hloov mus rau Lantus, qhov ntau thiab kev hloov ntawm cov tshuaj tau hloov pauv. Kev hloov pauv cov kua dej yuav tsum tau nqa tawm hauv tsev kho mob nkaus xwb.
Yog tias NPH insulins (Protafan NM, Humulin, thiab lwm yam) tau siv 2 zaug hauv ib hnub, ces Lantus Solostar feem ntau yog siv 1 zaug.
Tib lub sijhawm, thiaj li yuav txo tau kev pheej hmoo ntawm hypoglycemia, thawj koob tshuaj insulin glargine yuav tsum tsawg dua 30% piv nrog NPH.
Hauv lub neej yav tom ntej, tus kws kho mob saib cov piam thaj, tus neeg mob lub neej, qhov hnyav thiab kho rau ntau pawg uas tau tswj hwm. Tom qab peb lub hlis, cov hauj lwm zoo ntawm cov tshuaj kho tau tuaj yeem tshawb xyuas los ntawm kev soj ntsuam ntawm glycated hemoglobin.
kev qhia:
Insulin Lantus thaum cev xeeb tub
Cov kev tshawb fawb soj ntsuam ntawm Lantus nrog cov poj niam cev xeeb tub tsis tau ua. Raws li cov ntaub ntawv tsis raug cai, cov tshuaj tsis cuam tshuam loj heev hauv chav kawm ntawm cev xeeb tub thiab tus menyuam nws tus kheej.
Cov kev sim tau nrhiav rau ntawm cov tsiaj, thaum lub sijhawm nws tau ua pov thawj tias insulin glargine tsis muaj qhov phiv rau ntawm kev ua me nyuam.
Cev xeeb tub Lantus Solostar tuaj yeem siv tshuaj yog tias tsis muaj zog tiv thaiv NPH. Cov niam yav tom ntej yuav tsum saib xyuas lawv cov suab thaj, vim tias nyob rau thawj peb lub hlis, xav tau cov tshuaj insulin tuaj yeem txo qis, thiab hauv lub hlis thib ob thiab peb lub hlis.
Tsis txhob ntshai tsam pub niam mis rau tus menyuam noj, cov lus qhia tsis muaj cov ntaub ntawv uas Lantus tuaj yeem nkag mus rau niam mis tau.
Khaws cia li cas
Lub txee lub neej ntawm Lantus yog 3 xyoos. Koj yuav tsum muab cia rau hauv qhov chaw tsaus tiv thaiv los ntawm tshav ntuj ntawm qhov kub ntawm 2 txog 8 degrees. Feem ntau qhov chaw zoo tshaj plaws yog tub yees. Hauv qhov no, nco ntsoov saib cov txheej txheem kub, vim tias qhov txias khov ntawm cov tshuaj insulin Lantus yog txwv!
Txij li thaum siv thawj zaug, cov tshuaj yuav khaws cia rau ib hlis nyob rau hauv qhov chaw tsaus ntawm qhov kub ntawm tsis ntau tshaj 25 degrees (tsis nyob hauv tub yees). Tsis txhob siv cov tshuaj insulin uas tas sij hawm.
Qhov twg yuav, nqe
Lantus Solostar yog tshuaj dawb los ntawm kev muab tshuaj los ntawm cov kws kho keeb endocrinologist. Tab sis nws kuj tshwm sim uas tus neeg mob ntshav qab zib yuav tsum yuav nws cov tshuaj no ntawm nws tus kheej ntawm lub tsev muag tshuaj. Tus nqi nruab nrab ntawm cov tshuaj insulin yog 3300 rubles. Hauv Ukraine, Lantus tuaj yeem yuav rau 1200 UAH.
Tus kws kho ntshav qab zib hais tias nws yog ib qho zoo heev insulin, hais tias lawv qab zib yog khaws cia nyob rau hauv ib txwm txwv. Ntawm no yog cov neeg yuav hais dab tsi txog Lantus:
Feem ntau sab laug tsuas yog cov tshuaj xyuas qhov zoo. Ob peb cov neeg hais tias Levemir lossis Tresiba zoo dua rau lawv.
Cov tshuaj insulin lispro - cov lus qhia, tus nqi, tshuaj xyuas thiab cov qauv ntawm cov tshuaj
Lizpro insulin yog ib qho tshuaj ntawm tib neeg cov tshuaj insulin. Lub txiaj ntsig tseem ceeb ntawm cov tshuaj yog kev tswj hwm ntawm cov metabolism hauv qab ntuj. Txawm li cas los xij, nws muaj cov khoom anabolic (txhawb cov leeg nce ntxiv). Piv nrog cov tshuaj insulin luv luv, Lizpro insulin muaj qhov pib sai dua thiab qhov kawg ntawm cov nyhuv.
Kev Sib Sau thiab daim ntawv ntawm kev tso tawm
Lyspro insulin - cov tshuaj tua kab mob tsis haum xeeb rau kev tswj hwm kev siv dej thiab lub cev, muaj: • Cov khoom siv tseem ceeb: insulin lispro - 100ME, • Cheebtsam pabcuam: glycerol (glycerin), zinc oxide, metacresol, sodium hydrogen phosphate heptahydrate, 10% hydrochloric acid tov thiab / lossis 10% sodium hydroxide daws, dej.
Ntim. Tsib 3ml cartridges hauv hlwv lossis tsib 3ml cartridges hauv QuickPen koob txhaj tshuaj. Cov lus qhia, pob khoom ntawm cardboard.
Pharmacological kev txiav txim
Lizpro insulin yog DNA tso tawm cov tshuaj ntawm cov tshuaj insulin. Nws txawv hauv kev rov ua dua ntawm lysine thiab proline amino acid seem ntawm txoj haujlwm 28 thiab 29 ntawm cov kab hluav taws xob insulin B. Nws muaj peev xwm los cuam tshuam rau cov kev cai ntawm cov metabolism hauv cov piam thaj, muaj cov khoom ua haujlwm anabolic.
Nws ua rau kev hloov pauv ntawm cov piam thaj thiab amino acids mus rau lub cell, txhawb kev tsim cov glycogen los ntawm cov piam thaj hauv daim siab, inhibits gluconeogenesis, txhawb kev hloov pauv ntawm cov piam thaj ntau tshaj rau cov rog. Neeg insulin yog equimolar.
Nws muaj qhov pib ntawm kev ua sai dua li ntawm lwm cov tib neeg insulins, qhov ua ntej tshaj tawm ntawm lub ncov ntawm kev nqis tes ua, lub sijhawm luv luv ntawm kev ua haujlwm hypoglycemic.
Kev pib sai ntawm kev nqis tes ua (15 feeb tom qab txhaj tshuaj) cuam tshuam nrog kev nqus sai, uas tso cai rau koj nkag mus rau nws tam sim ntawd ua ntej noj mov, thaum tib neeg cov tshuaj insulin yuav tsum muab tshuaj rau hauv 30 feeb. ua ntej noj mov. Qhov chaw txhaj tshuaj cuam tshuam rau tus nqi ntawm kev nqus, nrog rau qhov pib ntawm nws qhov kev txiav txim. Qhov kev ua haujlwm siab tshaj plaws yog 0.5 - 2.5 teev, lub sijhawm ua haujlwm yog li 4 teev.
Kev ntsuas rau siv
- Cov neeg laus thiab menyuam yaus txij li 2 xyoos muaj mob ntshav qab zib hom 1.
- Hom 2 mob ntshav qab zib mellitus (nyob rau hauv cov ntaub ntawv tsis muaj txiaj ntsig ntawm cov ntsiav tshuaj).
Kev cuam tshuam nrog lwm yam tshuaj
Muaj cov tshuaj uas cuam tshuam rau cov metabolism hauv cov metabolism, thaum nce los yog txo qis yuav tsum muaj cov insulin.
Txo cov piam thaj: cov tshuaj tiv thaiv kab mob hauv lub cev, sulfonamides, ACE inhibitors, salicylates, angioprotectors, monoamine oxidase inhibitors, antiarrhythmic dysopyramides, narcotic analgesics.
Qab zib kom ntau: cov thyroid hormones, diuretics, sympathomimetics, tshuaj tiv thaiv qhov ncauj, phenothiazine derivatives, protease inhibitors.
Qee yam tshuaj muaj ob qho ua kom tsis pom kev thiab qhov ua tsis zoo. Cov no suav nrog:
- beta blockers thiab ntsev lithium,
- cawv
- clonidine (antihypertensive tshuaj).
Cov Yuav Tsum Muaj
- Nws yog txwv tsis pub siv rau hauv cov neeg mob uas tsis nkag siab rau insulin glargine lossis ntu sib xyaw.
- Kev ntshav siab.
- Kev kho mob ntawm cov ntshav qab zib ketoacidosis.
- Cov me nyuam qis dua 2 xyoos.
Ua tau qhov tsis zoo tshwm sim tsawg tsawg, cov lus qhia tau hais tias tej zaum yuav muaj:
- lipoatrophy los yog lipohypertrophy,
- kev ua xua (Quincke's edema, kev tsis haum, tshuaj bronchospasm),
- mob nqaij thiab mob qeeb hauv lub cev ntawm sodium ions,
- mob plab thiab qhov muag tsis pom kev.
Kev Hloov mus rau Lantus los ntawm lwm yam insulin
Yog hais tias tus mob ntshav qab zib tau siv cov tshuaj insulins-nruab nrab, tom qab ntawd thaum hloov mus rau Lantus, qhov ntau thiab kev hloov ntawm cov tshuaj tau hloov pauv. Kev hloov pauv cov kua dej yuav tsum tau nqa tawm hauv tsev kho mob nkaus xwb.
Yog tias NPH insulins (Protafan NM, Humulin, thiab lwm yam) tau siv 2 zaug hauv ib hnub, ces Lantus Solostar feem ntau yog siv 1 zaug.
Tib lub sijhawm, thiaj li yuav txo tau kev pheej hmoo ntawm hypoglycemia, thawj koob tshuaj insulin glargine yuav tsum tsawg dua 30% piv nrog NPH.
Hauv lub neej yav tom ntej, tus kws kho mob saib cov piam thaj, tus neeg mob lub neej, qhov hnyav thiab kho rau ntau pawg uas tau tswj hwm. Tom qab peb lub hlis, cov hauj lwm zoo ntawm cov tshuaj kho tau tuaj yeem tshawb xyuas los ntawm kev soj ntsuam ntawm glycated hemoglobin.
kev qhia:
Insulin Lantus thaum cev xeeb tub
Cov kev tshawb fawb soj ntsuam ntawm Lantus nrog cov poj niam cev xeeb tub tsis tau ua. Raws li cov ntaub ntawv tsis raug cai, cov tshuaj tsis cuam tshuam loj heev hauv chav kawm ntawm cev xeeb tub thiab tus menyuam nws tus kheej.
Cov kev sim tau nrhiav rau ntawm cov tsiaj, thaum lub sijhawm nws tau ua pov thawj tias insulin glargine tsis muaj qhov phiv rau ntawm kev ua me nyuam.
Cev xeeb tub Lantus Solostar tuaj yeem siv tshuaj yog tias tsis muaj zog tiv thaiv NPH. Cov niam yav tom ntej yuav tsum saib xyuas lawv cov suab thaj, vim tias nyob rau thawj peb lub hlis, xav tau cov tshuaj insulin tuaj yeem txo qis, thiab hauv lub hlis thib ob thiab peb lub hlis.
Tsis txhob ntshai tsam pub niam mis rau tus menyuam noj, cov lus qhia tsis muaj cov ntaub ntawv uas Lantus tuaj yeem nkag mus rau niam mis tau.
Khaws cia li cas
Lub txee lub neej ntawm Lantus yog 3 xyoos. Koj yuav tsum muab cia rau hauv qhov chaw tsaus tiv thaiv los ntawm tshav ntuj ntawm qhov kub ntawm 2 txog 8 degrees. Feem ntau qhov chaw zoo tshaj plaws yog tub yees. Hauv qhov no, nco ntsoov saib cov txheej txheem kub, vim tias qhov txias khov ntawm cov tshuaj insulin Lantus yog txwv!
Txij li thaum siv thawj zaug, cov tshuaj yuav khaws cia rau ib hlis nyob rau hauv qhov chaw tsaus ntawm qhov kub ntawm tsis ntau tshaj 25 degrees (tsis nyob hauv tub yees). Tsis txhob siv cov tshuaj insulin uas tas sij hawm.
Qhov twg yuav, nqe
Lantus Solostar yog tshuaj dawb los ntawm kev muab tshuaj los ntawm cov kws kho keeb endocrinologist. Tab sis nws kuj tshwm sim uas tus neeg mob ntshav qab zib yuav tsum yuav nws cov tshuaj no ntawm nws tus kheej ntawm lub tsev muag tshuaj. Tus nqi nruab nrab ntawm cov tshuaj insulin yog 3300 rubles. Hauv Ukraine, Lantus tuaj yeem yuav rau 1200 UAH.
Tus kws kho ntshav qab zib hais tias nws yog ib qho zoo heev insulin, hais tias lawv qab zib yog khaws cia nyob rau hauv ib txwm txwv. Ntawm no yog cov neeg yuav hais dab tsi txog Lantus:
Feem ntau sab laug tsuas yog cov tshuaj xyuas qhov zoo. Ob peb cov neeg hais tias Levemir lossis Tresiba zoo dua rau lawv.
Cov tshuaj insulin lispro - cov lus qhia, tus nqi, tshuaj xyuas thiab cov qauv ntawm cov tshuaj
Lizpro insulin yog ib qho tshuaj ntawm tib neeg cov tshuaj insulin. Lub txiaj ntsig tseem ceeb ntawm cov tshuaj yog kev tswj hwm ntawm cov metabolism hauv qab ntuj. Txawm li cas los xij, nws muaj cov khoom anabolic (txhawb cov leeg nce ntxiv). Piv nrog cov tshuaj insulin luv luv, Lizpro insulin muaj qhov pib sai dua thiab qhov kawg ntawm cov nyhuv.
Kev Sib Sau thiab daim ntawv ntawm kev tso tawm
Lyspro insulin - cov tshuaj tua kab mob tsis haum xeeb rau kev tswj hwm kev siv dej thiab lub cev, muaj: • Cov khoom siv tseem ceeb: insulin lispro - 100ME, • Cheebtsam pabcuam: glycerol (glycerin), zinc oxide, metacresol, sodium hydrogen phosphate heptahydrate, 10% hydrochloric acid tov thiab / lossis 10% sodium hydroxide daws, dej.
Ntim. Tsib 3ml cartridges hauv hlwv lossis tsib 3ml cartridges hauv QuickPen koob txhaj tshuaj. Cov lus qhia, pob khoom ntawm cardboard.
Pharmacological kev txiav txim
Lizpro insulin yog DNA tso tawm cov tshuaj ntawm cov tshuaj insulin. Nws txawv hauv kev rov ua dua ntawm lysine thiab proline amino acid seem ntawm txoj haujlwm 28 thiab 29 ntawm cov kab hluav taws xob insulin B. Nws muaj peev xwm los cuam tshuam rau cov kev cai ntawm cov metabolism hauv cov piam thaj, muaj cov khoom ua haujlwm anabolic.
Nws ua rau kev hloov pauv ntawm cov piam thaj thiab amino acids mus rau lub cell, txhawb kev tsim cov glycogen los ntawm cov piam thaj hauv daim siab, inhibits gluconeogenesis, txhawb kev hloov pauv ntawm cov piam thaj ntau tshaj rau cov rog. Neeg insulin yog equimolar.
Nws muaj qhov pib ntawm kev ua sai dua li ntawm lwm cov tib neeg insulins, qhov ua ntej tshaj tawm ntawm lub ncov ntawm kev nqis tes ua, lub sijhawm luv luv ntawm kev ua haujlwm hypoglycemic.
Kev pib sai ntawm kev nqis tes ua (15 feeb tom qab txhaj tshuaj) cuam tshuam nrog kev nqus sai, uas tso cai rau koj nkag mus rau nws tam sim ntawd ua ntej noj mov, thaum tib neeg cov tshuaj insulin yuav tsum muab tshuaj rau hauv 30 feeb. ua ntej noj mov. Qhov chaw txhaj tshuaj cuam tshuam rau tus nqi ntawm kev nqus, nrog rau qhov pib ntawm nws qhov kev txiav txim. Qhov kev ua haujlwm siab tshaj plaws yog 0.5 - 2.5 teev, lub sijhawm ua haujlwm yog li 4 teev.
Kev ntsuas rau siv
• Hom 1 mob ntshav qab zib mellitus, thaum thev tsis taus rau lwm tus insulins,
• Postprandial hyperglycemia uas tsis tuaj yeem kho los ntawm lwm cov insulins, • Hom 2 mob ntshav qab zib uas tsis muaj peev xwm noj tshuaj hypoglycemic hauv qhov ncauj, • Tsis tuaj yeem nqus lwm cov tshuaj insulins,
• Kev khiav dej num thiab kab mob sib kis hauv cov ntshav qab zib.
Tsuas tshuaj thiab tswj hwm
Lyspro insulin dosage yuav tsum tau muab xam raws theem ntawm glycemia.
Yog tias tsim nyog, nws raug tswj nrog kev sib xyaw nrog insulins ntev lossis nrog tshuaj sulfonylureas.
Kev txhaj tshuaj yog tsim hauv qab daim tawv nqaij hauv lub xub pwg, lub duav, lub plab thiab pob tw. Qhov chaw txhaj tshuaj yog hloov chaw thiaj li tsis siv ntxiv ntau dua ib hlis ib zaug. Nco ntsoov ceev faj nrog kev sib ze ntawm cov hlab ntshav.
Cov neeg mob lub raum lossis mob hepatic tsis txaus yuav muaj qhov nce siab ntxiv ntawm lub cev ntshav, thiab qhov kev xav tau tsawg dua rau nws, uas yuav tsum tau soj ntsuam tas li ntawm cov qib glycemia, nrog rau cov tshuaj kho kom raws sijhawm.
Noj ntau dhau
Qhov tshwm sim: kev tawm hws, tawg hws, tachycardia, tshee tshee, tshaib plab, ntxhov siab, mob plab tawg ntawm lub qhov ncauj, pallor, mob taub hau, tshee tshee, tsaug zog, ntuav, pw tsaug zog, ntshai, txob taus, nyuaj siab, tsis muaj zog, tsis pom kev thiab hais lus, tsis meej pem , kev chua leeg, hypoglycemic coma.
Kev Kho Mob: thaum tus neeg mob nco qab, koj yuav tsum txhaj tshuaj dextrose los yog txhaj tshuaj glucagon lossis kho hypertonic ntawm dextrose. Kev txhim kho ntawm lub qog ua kom nyob tsis tsaug zog kom yuav tsum tau txhaj tshuaj dextrose tov kom txog thaum tus neeg mob tawm ntawm lub cev tsis xeev.
Cov tshuaj sib cuam tshuam
Tsis sib haum nrog lwm cov tshuaj daws teeb meem.
Hypoglycemic nyhuv ntawm insulin txhim khu sulfonamides, Mao inhibitors, carbonic anhydrase, ACE, anabolic steroids, narcotics yuav muab, androgens, bromocriptine, tetracyclines, ketoconazole, clofibrate, mebendazole, theophylline, fenfluramine, lithium npaj, cyclophosphamide, pyridoxine, quinine, chloroquine, quinidine, ethanol.
Weaken lub hypoglycemic effect: glucagon, somatropin, corticosteroids, txwv rau kev tswj hwm ntawm qhov ncauj, estrogens, thiazide thiab lub voj diuretics, BMKK, heparin, thyroid hormones, calcium calcium, tshuaj tiv thaiv calcium, calcium calcium, tshuaj tiv thaiv kab mob, calcium calcium, tshuaj tiv thaiv kab mob, calcium calcium, tshuaj tiv thaiv kab mob, calcium calcium, tshuaj tiv thaiv kab mob calcium, calcium calcium , nicotine, phenytoin, epinephrine.
Cov nyhuv hauv kev ua haujlwm hauv insulin yog muaj peev xwm ua kom tsis muaj zog thiab ntxiv dag zog beta-blockers, reserpine, pentamidine, octreotide.
Cov lus qhia tshwj xeeb
Yuav tsum ua raws li txoj kev tswj hwm nruj.
Thaum hloov chaw cov neeg mob rau lyspro insulin nrog kev siv tshuaj insulin sai sai ntawm tsiaj keeb kwm, kev hloov pauv koob tshuaj yog ua tau. Yog tias tus neeg mob qhov koob tshuaj txhua hnub dhau 100ED, hloov los ntawm ib hom tshuaj insulin mus rau lwm qhov yuav tsum tau nqa hauv tsev kho mob.
Qhov xav tau ntxiv cov tshuaj insulin nce ntxiv nrog cov kab mob sib kis, kev nyuaj siab ntxhov siab, nce ntawm cov khoom noj carbohydrates hauv cov zaub mov, thaum noj tshuaj nrog hyperglycemic kev ua si (cov thyroid hormones, GCS, qhov ncauj tiv thaiv kab mob, thiazide diuretics, thiab lwm yam).
Qhov xav tau rau cov insulin poob qis nrog lub raum lossis lub siab ua haujlwm, qhov qis ntawm cov khoom noj carbohydrates hauv zaub mov, nce kev tawm dag zog, thaum noj tshuaj nrog hypoglycemic kev ua si (tsis xaiv cov beta-blockers, MAO inhibitors, sulfonamides).
Txoj kev pheej hmoo ntawm hypoglycemia worsens lub peev xwm ntawm tus mob ntshav qab zib tsav lub tsheb, raws li tau zoo raws li kev kho tsheb.
Tus mob ntshav qab zib tuaj yeem nres ntshav qab zib tsawg mus ntawm lawv tus kheej los ntawm kev noj cov piam thaj lossis zaub mov uas muaj cov carbohydrates ntau. Nws yog ib qho tseem ceeb uas yuav tau qhia rau tus kws kho mob uas tau kawm txog qhov hloov pauv hypoglycemia, uas yog qhov tsim nyog rau tshuaj kho kom haum.
SAWV DAWS SAWV DAWS
«Cib Toom"- ib qho kev ua tau lub zog antioxidant hnyav uas muab lub neej tshiab zoo rau ob qho tib si metabolic syndrome thiab ntshav qab zib. Qhov ua tau zoo thiab kev nyab xeeb ntawm cov tshuaj yog qhov tseeb tau hais tawm. Cov tshuaj yog raug pom zoo rau kev siv los ntawm Lavxias Diabetes Association. Tshawb nrhiav ntxiv >>> |
Ob-theem insulin Lizpro (Humalog)
Cov neeg mob ntshav qab zib feem ntau yuav tsum siv cov tshuaj insulin-uas muaj.
Cov no suav nrog Lizpro insulin, uas yog siv dav dav siv los tswj ntshav qab zib.
Txhawm rau kom nkag siab cov ntsiab cai ntawm kev kho nrog nws cov kev pab, cov neeg mob yuav tsum paub lub ntsiab tseem ceeb ntawm cov tshuaj no.
Tus yam ntxwv dav
Lub npe lag luam rau cov tshuaj yog Humalog Mix. Nws yog nce raws li ib qho kab xev ntawm tib neeg cov kua dej. Cov tshuaj muaj cov nyhuv hypoglycemic, pab kom nrawm rau kev ua kom zoo ntawm cov piam thaj, thiab kuj tswj cov txheej txheem ntawm nws qhov kev tso tawm. Cov cuab yeej yog kev ua haujlwm ob-theem txhaj tshuaj.
Ntxiv rau cov tshuaj yeeb dej caw tseem ceeb, muaj pes tsawg leeg muaj cov khoom sib xyaw ua ke:
- metacresol
- glycerol
- sodium hydroxide nyob rau hauv daim ntawv ntawm tov (los yog hydrochloric acid),
- zinc oxide
- sodium heptahydrate hydrogen phosphate,
- dej.
Txhawm rau siv cov tshuaj no, koj xav tau kev teem caij ntsib kws kho mob nrog cov lus qhia meej. Nws tsis tuaj yeem yuav tsum kho qhov kev noj tshuaj lossis lub sijhawm siv rau ntawm koj tus kheej.
Cov lus qhia rau kev siv
Txhawm rau kom tsis txhob ua rau pom qhov tsis zoo los ntawm kev siv Lizpro insulin, koj yuav tsum ua raws nraim li cov lus qhia rau cov tshuaj no.
Qhov ntau npaum ntawm cov tshuaj nyob ntawm ntau cov nta. Qhov no cuam tshuam rau tus neeg mob lub hnub nyoog, daim ntawv ntawm tus kab mob thiab nws qhov mob hnyav, cov kab mob sib kis, thiab lwm yam Yog li ntawd, kev txiav txim qhov koob tshuaj yog qhov ua haujlwm ntawm tus kws kho mob koom.
Tab sis tus kws kho mob tshwj xeeb yuav yuam kev, yog li cov chav kawm ntawm kev kho mob yuav tsum tau saib xyuas tas li los soj ntsuam cov ntshav qab zib thiab kho cov txheej txheem kev kho mob. Tus neeg mob yuav tsum tau saib xyuas nws txoj kev noj qab haus huv zoo thiab qhia tus kws kho mob txog txhua yam kev tsis zoo ntawm lub cev mus rau yeeb tshuaj.
Tsim cov ntawv qhia chaw nyob li cas. Tab sis tsis zoo li feem ntau cov tshuaj zoo sib xws, kev txhaj tshuaj intramuscular tseem raug tso cai, ntxiv rau kev qhia cov tshuaj insulin rau hauv txoj hlab ntshav. Kev txhaj tshuaj rau hauv plab yuav tsum tau ua nrog kev koom tes ntawm tus kws kho mob.
Cov chaw zoo tshaj plaws rau kev txhaj tshuaj subcutaneous yog thaj chaw hauv ceg, lub xub pwg, lub pob tw, lub hauv pliaj xub thawj. Kev qhia ntawm cov tshuaj mus rau tib thaj chaw tsis raug tso cai, vim qhov no ua rau lipodystrophy. Yuav tsum muaj kev txav mus los hauv thaj chaw uas tau xaiv tseg.
Kev txhaj tshuaj yuav tsum tau ua nyob rau hauv ib lub sijhawm ntawm ib hnub. Qhov no yuav ua rau lub cev hloov kho thiab muab cov tshuaj insulin txuas ntxiv.
Nws yog ib qho tseem ceeb xav txog tus neeg mob tej teeb meem kev noj qab haus huv (tsis yog mob ntshav qab zib). Vim qee qhov ntawm lawv, cov nyhuv ntawm cov tshuaj no tuaj yeem ua rau txawv txav lossis qis dua. Hauv qhov no, koj yuav tsum tau rov qab suav lub koob tshuaj. Hauv kev sib txuas nrog lwm cov pathologies, tus kws kho mob feem ntau yuav txwv tsis pub siv cov Humalog.
Xiav mem nyeem:
Sab nraud thiab contraindications
Nws yog qhov nyuaj kom tuaj yeem lav qhov tsis muaj kev puas tsuaj los ntawm kev siv tshuaj, tab sis kev pheej hmoo tuaj yeem txo qis, muab cov kev sib kis uas twb muaj lawm. Lizpro tseem muaj lawv, thiab tus kws kho mob, taw nws, yuav tsum ua kom tus neeg mob tsis muaj lawv.
Lub ntsiab contraindications yog:
- kev nkag siab ib leeg rau cov tshuaj ntawm cov tshuaj,
- siab feem ntau rau hypoglycemia,
- muaj cov insulinomas.
Hauv cov xwm txheej zoo li no, Humalog yuav tsum tau hloov nrog lwm cov tshuaj uas muaj cov txiaj ntsig zoo sib xws, tab sis tsis muaj kev phom sij.
Tsis tas li, thaum kho nrog tshuaj insulin, nws yog ib qho tsim nyog yuav tsum coj mus rau hauv tus account qhov tshwm sim tshwm sim. Qhov tshwm sim ntawm qee qhov tsis ua rau muaj kev hem thawj, txij li lawv los ntawm qhov ua tsis tiav ntawm lub cev tsis haum rau cov tshuaj muaj yees.
Tom qab lub sijhawm luv luv, tus neeg tau txais siv mus txhaj, thiab cov kev phiv tshem tawm. Lwm pawg kev mob tshwm sim qhia tias muaj kev nkag tsis tau rau cov khoom no. Cov tsos mob no tsis ploj nrog lub sijhawm, tab sis tsuas yog kev nce qib, tsim kev phom sij tseem ceeb. Yog tias lawv tshwm sim, nws raug nquahu kom thim kev kho mob nrog ib tus neeg sawv cev tiv thaiv insulin.
Feem ntau feem ntau hu ua cov kev mob tshwm sim ntawm lub Humalog, raws li:
- Kev ntshav siabCov. Qhov no yog qhov cuam tshuam tshaj plaws, vim hais tias vim nws tus neeg mob tau hem nrog kev tuag lossis kev puas tsuaj loj hauv lub hlwb.
- LipodystrophyCov. Cov yam ntxwv no cuam tshuam kev ua txhaum ntawm kev nqus ntawm cov tshuaj. Nws ua tau kom txo qhov ntxim nyiam ntawm nws tshwm sim los ntawm kev hloov chaw rau kev txhaj tshuaj.
- Ua xua qhov tshwm simCov. Lawv tuaj yeem sib txawv ntau - los ntawm me me ntawm daim tawv nqaij liab mus rau qhov tsis txaus ntseeg tsis nco ceev.
- Pom kev tsis pom kevCov. Cov neeg mob tuaj yeem pib ua tus mob retinopathy, thiab qee zaum lawv lub zeem muag raug txo qis.
- Kev tiv thaiv hauv zosCov. Lawv zoo ib yam li ua xua, tab sis tsuas tshwm sim ntawm cov chaw txhaj tshuaj. Cov no suav nrog khaus, o, liab thiab lwm yam Feem ntau, cov xwm txheej zoo li ploj mus qee lub sijhawm tom qab pib kho.
Yog tias muaj qhov tshwm sim txawv txawv, tus neeg mob yuav tsum sab laj nrog kws kho mob kom paub tseeb tias tsis muaj kev phom sij.
Cov yam ntxwv ntawm kev cuam tshuam nrog lwm yam tshuaj
Ib qho tseem ceeb heev ntawm kev siv tshuaj yog nws qhov kev sib raug zoo nrog lwm yam tshuaj. Cov kws kho mob feem ntau yuav tsum tau kho ob peb pathologies tib lub sijhawm, vim tias nws yog qhov tsim nyog los ua ke rau kev txais tos ntawm cov tshuaj sib txawv.Nws yog ib qho tsim nyog los teeb tsa txoj kev kho kom cov tshuaj tsis thaiv ntawm txhua qhov kev ua.
Qee zaum muaj qhov xav tau ntawm kev siv tshuaj uas tuaj yeem cuam tshuam qhov kev ua ntawm insulin.
Nws lub zog yog nce ntxiv yog tias, ntxiv rau nws, tus neeg mob siv cov tshuaj hauv qab no:
- Clofibrate
- Ketoconazole,
- MAO inhibitors
- sulfonamides.
Yog tias koj tsis tuaj yeem tsis kam lees txais lawv, koj yuav tsum txo qhov koob tshuaj ntawm nplooj ntawv qhia Humalog.
Cov yeeb tshuaj hauv qab no thiab cov pab pawg ntawm cov neeg sawv cev tuaj yeem ua kom tsis muaj zog ntawm cov tshuaj hauv nqe lus nug:
- estrogens
- nicotine
- tshuaj hormonal rau kev tiv thaiv,
- Glucagon.
Vim tias cov tshuaj no, qhov ua haujlwm ntawm Lizpro yuav txo qis qis, yog li tus kws kho mob yuav tau pom zoo kom nce ntxiv hauv cov tshuaj.
Qee cov tshuaj muaj qee yam tshwm sim tsis tau. Lawv muaj peev xwm nce ntxiv thiab txo qis kev ua haujlwm ntawm cov tshuaj nquag. Cov no suav nrog Octreotide, Pentamidine, Reserpine, beta-blockers.
Cov nqi thiab cov qauv ntawm cov tshuaj
Kev kho mob nrog Insulin Lyspro nws kim heev. Tus nqi ntawm ib pob ntawm cov tshuaj zoo li txawv ntawm 1800 txog 200 rubles. Nws yog vim tias tus nqi siab uas tus neeg mob qee zaum thov tus kws kho mob kom hloov cov tshuaj no nrog nws cov tshuaj tiv thaiv nrog cov nqi pheej yig dua.
Muaj ntau ntau cov analogues ntawm cov tshuaj no. Lawv raug nthuav tawm los ntawm cov ntawv sib txawv ntawm cov ntawv tso tawm, yuav txawv hauv lawv muaj pes tsawg leeg.
Ntawm cov neeg tseem ceeb tuaj yeem hais:
Qhov kev xaiv ntawm cov tshuaj los hloov cov hom insulin no yuav tsum tau muab rau tus kws tshwj xeeb.
Daim ntawv tso tawm
Humalog muaj nyob rau subcutaneous thiab cov leeg tswj hwm ntawm 100 IU hauv 3 ml cartridges. Lub cartridge sib xyaw ua ke hauv cov cwj mem tshwj xeeb rau kev siv rov qab. Dosage tsis siv cov ntaub ntawv rau kev tswj hwm qhov ncauj.
Tus kws kho mob xaiv cov ntau npaum ntawm cov tshuaj ib tus zuj zus. Qhov kev txhaj tshuaj yog ua 5 txog 15 feeb ua ntej noj mov. Ib koob tshuaj ntawm 40 units, tshaj nws raug tso cai nyob rau hauv muaj xwm txheej hnyav. Thaum siv "Humalog" rau kev kho mob hlwb, nws siv tau txog 4-6 zaug hauv ib hnub. Yog hais tias cov kev kho mob ua ke, tom qab ntawd cov tshuaj ntxiv nrog cov tshuaj insulin ntev, muab 3 zaug hauv ib hnub.
Lwm hom tshuaj yog Humalog Mix insulin. Qhov tshuaj biphasic no yog ib nrab ntawm cov insulin lispro ua sai thiab ib nrab ntev ua rau muaj cov insulin lispro.
Pharmacodynamics thiab pharmacokinetics
Cov tshuaj Humalog muaj cov lus qhia hypoglycemic. Nws yog DNA hloov kho cov kab mob sib piv ntawm tib neeg cov kua dej. Qhov txawv loj yog qhov hloov ntawm qhov piv ntawm cov amino acids rau insulin B-saw.
Cov lus piav qhia tau hais tias cov tshuaj hloov cov piam thaj hauv ntshav qab zib, yog tus cwj pwm ntawm anabolic. Thaum nws nkag mus rau hauv cov leeg, cov concentration ntawm glycogen, glycerol, cov roj ntsha rog nce ntxiv, cov tshuaj synthesis tau nce ntxiv, thiab kev noj cov amino acids yuav nce ntxiv. Tib lub sijhawm, ketogenesis, glucogenesis, lipolysis, amino acid tso tawm cov txheej txheem thiab protein catabolism ib txhij txo.
Tus nqi ntawm kev nqus thiab feem pua, nrog rau tus nqi kuaj pom ntawm qhov tshwm sim nyob ntawm qhov chaw txhaj tshuaj - ncej, pob tw, plab. Tsis tas li ntawd, ntau npaum li cas, cov tshuaj insulin hauv 1 ml ntawm cov tshuaj cuam tshuam rau tus txheej txheem no.
Hauv cov ntaub so ntswg, cov tshuaj nquag tau faib tsis sib luag. Nws hla tsis dhau lub plab, tsis hla mus rau niam mis. Kev rhuav tshem ua rau cov insulinase feem ntau nyob hauv lub raum thiab lub siab. Kev zam los ntawm ob lub raum 30 - 80%.
Kev taw qhia thiab contraindications
Qhov tseem ceeb tshaj plaws rau kev siv ntawm cov tshuaj Humalog yog ntshav qab zib mellitus insulin-kev tiv thaiv lossis tsis siv tshuaj insulin nyob hauv tus menyuam lossis tus neeg laus, thaum nws tau tsim nyog los tswj cov tshuaj insulin hauv cov ntshav mus rau li qub. Kuj qhov taw qhia yog mob insulin.
Thaum cev xeeb tub, cov tshuaj tsis muaj kev cuam tshuam rau lub cev ntawm tus poj niam thiab tus menyuam hauv plab. Yog tias tus ntxhais xeeb tub, tom qab ntawd nws yuav tsis cuam tshuam nrog kev kho mob nrog cov tshuaj, tab sis nco ntsoov sab laj nrog endocrinologist rau kev hloov kho koob.
Contraindications suav nrog:
- hypoglycemia thiab ib tug nyiam rau nws tshwm sim,
- siab rhiab nyob rau hauv kev sib raug zoo rau cov tshuaj muaj pes tsawg leeg.
Tsuas tshuaj thiab tshaj
Cov tshuaj yog txhaj subcutaneously lossis siv rau lub sijhawm ntev subcutaneous infusions nrog lub tshuab nqus ntshav.
Koj xav tau ntau npaum li casdaws rau kev tswj hwm, tus kws kho mob teeb tsa raws li cov ntsiab lus qabzib hauv cov hlab ntshav. Lub hom kuj tseem xaiv tus kheej. Koj tuaj yeem muab kev txhaj tshuaj ua ntej noj mov lossis yuav luag tam sim ntawd tom qab noj mov. Nws yog ib qho tseem ceeb kom tswj tau chav sov ntawm cov tshuaj.
Nrog txoj kev loj hlob ntawm ketoacidosis, ntawm kev ua haujlwm lossis tom qab kev phais mob nyob rau theem rov qab, nrog txoj kev mob loj, nws muaj cai siv tshuaj los daws cov tshuaj. Subcutaneously, qhov no yog ua hauv lub xub pwg, pob tw, ncej puab lossis lub plab. Cov kem txhaj tshuaj hloov kho kom lwm qhov chaw tsis ntau tshaj 1 zaug hauv ib hlis.
Nws yog qhov tsim nyog yuav tsum ua haujlwm ntawm lub Humalog raws li txoj cai, nws yuav tsum tsis txhob mus rau hauv lub nkoj. Tom qab txhaj tshuaj, qhov chaw txhaj tshuaj tsis yog zaws. Tus kws kho mob yuav qhia tus neeg mob txog cov txheej txheem uas yog rau kev txhaj tshuaj nws tus kheej.
Txheej txheem cov txheej txheem
- Ntxuav tes kom huv nrog xab npum thiab dej.
- Kho thaj chaw txhaj tshuaj.
- Tshem tawm lub hau ntawm rab koob.
- Kho cov tawv nqaij, sib sau ua ke ntawm daim ntau quav, ntxig rab koob thiab ua kev txhaj tshuaj los ntawm nias lub khawm ntawm lub koob txhaj tshuaj.
- Ua tib zoo tshem tawm rab koob thiab nyem qhov chaw txhaj tshuaj nrog lub paj rwb qhwv, tuav ob peb feeb, txhuam tawv ncauj yog txwv tsis pub.
- Siv lub hau tiv thaiv, hle rab koob thiab pov tseg.
- Qee zaum ib qho tshuaj xav kom mus nrog dej qab ntsev. Cov kab mob tau tsim los ntawm tus kws tshaj lij.
Nyob rau hauv cov ntaub ntawv ntawm kev siv tshuaj ntau dhau, qhov kev soj ntsuam cov duab ntawm hypoglycemia loj hlob. Nws yog manifested los ntawm tej lub cim:
- qaug zog thiab cia,
- tawm hws,
- kev tshaib kev nqhis
- tshee hnyo
- lub plawv dhia,
- kiv tob hau thiab mob taub hau
- pom kev pom
- tsis meej pem pem
- ntuav
Lub teeb ua teeb meem ntawm hypoglycemia tuaj yeem nres tau yooj yim los ntawm kev noj ntshav qab zib lossis qab zib nrog zaub mov. Yog tias muaj mob hnyav ntxiv tshwm sim, nws yuav tsum qhia tus kws kho mob txog qhov no.
Cov ntshav qog ntshav ntshav qis me ntsis raug kho los ntawm kev txhaj tshuaj subcutaneous lossis intramuscular nrog glucagon. Tom qab ntawd, tom qab ruaj khov, koj yuav tsum noj zaub mov carbohydrate. Thaum tsis muaj qhov zoo ntawm qhov ua tau zoo tom qab glucagon, dextrose hauv kev daws tau muab tso ncaj ncees.
Xaus
Humalog yog thawj zaug ua kom zoo-ua yeeb yam insulin. Nws ua tom qab ib hlis plaub ntawm ib teev, vim tias cov suab thaj hauv cov ntshav xa mus rau cov ntaub so ntswg, txawm hais tias lub sijhawm luv luv-hyperglycemia tsis loj hlob. Piv rau nws cov analogues, Humalog muaj qhov kev txiav txim ntawm qhov ntau dua tau zoo. Hauv 22%, txhua hnub kev hloov ua kua nplaum tsis tshwm sim, glycemia normalizes, thiab cov kev pheej hmoo ntawm qeeb hypoglycemia yog txo qis. Qhov insulin no yog qhov nrawm tshaj plaws thiab ruaj khov.