Biosynthetic insulin Humulin: tus nqi ntawm ntau hom kev tso tawm ntawm cov tshuaj thiab cov nuances ntawm lawv siv

Lub Npe Lag Luam: Humulin Tsis tu ncua

Lub Npe Tsis Pub Hauv Lub Npe: Soluble insulin (tib neeg kev tsim kho tshuab)

Daim ntawv noj tshuaj: txhaj tshuaj siv

Yam tshuaj muaj zog: insulin neutral soluble biosynthetic tib neeg

Pab pawg kws tshuaj: luv-ua neeg insulin

Kws tshuaj: Tib neeg siv tshuaj insulin DNA insulin. Nws yog lub sijhawm luv luv-insulin npaj. Lub txiaj ntsig tseem ceeb ntawm cov tshuaj yog kev tswj hwm ntawm cov metabolism hauv qab ntuj. Tsis tas li ntawd, nws muaj qhov ua kom anabolic. Hauv cov leeg nqaij thiab lwm cov nqaij (tshwj tsis yog lub hlwb), cov roj ntsha insulin ua rau thauj cov ntshav qabzib thiab amino acids nrawm nrawm, ua kom muaj protein ntau anabolism. Insulin txhawb kev hloov pauv ntawm cov piam thaj rau glycogen hauv lub siab, inhibits gluconeogenesis thiab txhawb kev hloov pauv ntawm cov piam thaj rau cov rog. Qhov pib ntawm kev ua ntawm cov tshuaj yog 30 feeb tom qab kev tswj hwm, qhov ua haujlwm siab tshaj plaws ntawm 1 thiab 3 teev, lub sijhawm ua haujlwm yog 5-7 teev.

Kev taw qhia rau kev siv:

Mob ntshav qab zib mellitus nrog kev taw qhia rau kev kho tshuaj insulin, ua ntej kuaj mob ntshav qab zib mellitus, cev xeeb tub nrog ntshav qab zib hom 2 mellitus (non-insulin-dependant).

Cov Tshuaj Tiv Thaiv:

Cov tshuaj tiv thaiv ntshav qab zib, kev tsis txaus siab rau cov tshuaj insulin lossis rau ib qho ntawm cov tshuaj.

Muab thiab kev coj:

Cov koob tshuaj yog txiav txim los ntawm tus kws kho mob ib leeg zuj zus, nyob ntawm seb muaj qib glycemia. Cov tshuaj yuav tsum tau muab tshuaj s / c, nyob rau hauv / hauv, tej zaum nyob rau hauv / m kev qhia. Cov tshuaj SC tau muab rau lub xub pwg, ncej puab, pob tw los yog plab. Qhov chaw txhaj tshuaj yuav tsum tau hloov chaw kom tib qhov chaw siv tsis ntau tshaj li 1 sijhawm / hli. Thaum s / mus rau kev taw qhia, yuav tsum tau saib xyuas kom tsis txhob nkag mus rau hauv cov hlab ntshav. Tom qab txhaj tshuaj, qhov chaw txhaj tshuaj yuav tsum tsis txhob zaws. Cov neeg mob yuav tsum tau kawm paub txog kev siv tshuaj insulin kom raug. Cartridges thiab vials ntawm Humulin Tsis tas yuav tsum tau rov ua haujlwm thiab tsuas yog siv tau yog tias lawv cov ntsiab lus yog qhov ntshiab, tsis muaj kob uas tsis muaj qhov pom. Daim cartridges thiab vials yuav tsum tau kuaj xyuas kom zoo. Koj yuav tsum tsis txhob siv cov tshuaj yog tias nws muaj plaub ya ri, yog tias cov khoom sib xyaw dawb dawb txuam rau hauv qab lossis phab ntsa ntawm lub raj mis, tsim cov nyhuv ntawm ib qho qauv khov. Cov cuab yeej ntawm cov cartridges tsis pub sib xyaw lawv cov ntsiab lus nrog lwm cov insulins ncaj qha hauv daim cartridge nws tus kheej. Cartridges tsis yog yuav tsum kom thim rov qab. Cov ntsiab lus ntawm lub vial yuav tsum tau sau mus rau hauv ib qho tshuaj insulin raws li lub zog ntawm cov tshuaj insulin muab rau, thiab cov koob tshuaj xav tau ntawm cov tshuaj insulin yuav tsum raug tswj hwm raws li kws kho mob hais. Thaum siv daim cartridges, ua raws cov khw muag cov lus qhia rau lub thawv ntim thiab muab cov koob tso rau. Cov tshuaj yuav tsum tau muab nyob rau hauv raws li cov chaw tsim tshuaj paus cov lus qhia rau cov xaum qhuav. Siv cov hau ntawm sab nraud ntawm rab koob, tam sim ntawd tom qab ntxig tawm, unscrew lub koob thiab xyuam xim pov tseg nws. Tshem tawm rab koob tam sim ntawd tom qab txhaj tshuaj tiv thaiv kab mob ua kom tsis muaj menyuam, tiv thaiv kev paim quav, huab cua huab cua thiab kis tau ntawm rab koob. Tom qab ntawv muab lub hau kaw. Koob yuav tsum tsis txhob siv cov khoom tshiab. Koob thiab rab koob uas yuav tsum tsis txhob siv los ntawm lwm tus neeg. Cartridges thiab vials yog siv kom txog thaum lawv khoob, tom qab uas lawv yuav tsum tau muab pov tseg. Kev Siv Humulin Muaj peev xwm muab tau ua ke nrog Humulin NPH. Rau qhov no, insulin luv yeeb yam yuav tsum tau kos rau hauv cov koob txhaj ua ntej kom tiv thaiv cov insulin ua yeeb yam ntev dua los ntawm nkag mus rau hauv lub thauv. Nws raug nquahu kom paub qhov kev npaj sib xyaw tom qab sib tov. Txhawm rau tswj hwm tus nqi npaum li cas ntawm txhua hom tshuaj insulin, koj tuaj yeem siv cov koob txhaj tshuaj cais rau Humulin Tsis tu ncua thiab Humulin NPH. Koj yuav tsum tau siv cov koob tshuaj insulin uas phim cov tshuaj insulin txhaj tshuaj.

Phiv los sis:

Kev phiv cuam tshuam nrog cov nyhuv tseem ceeb ntawm cov tshuaj: hypoglycemia. Kev mob ntshav qis heev tuaj yeem ua rau tsis nco qab thiab (tshwj tsis yog kis) tuag. Ua xua: muaj kev fab rau lub zos yog ua tau - hyperemia, o lossis khaus ntawm qhov chaw txhaj tshuaj (feem ntau tso tseg li ntawm ob peb hnub mus rau ntau lub lis piam), kev tiv thaiv kab mob tsis haum (tshwm sim tsawg dua, tab sis muaj dua) - ua pob khaus, ua tsis taus pa, ua pa luv , txo cov ntshav siab, ntshav nce siab, nce hws. Cov uas muaj mob hnyav raug neeg lub cev tuaj yeem tas sim neej. Lwm yam: qhov ntxim nyiam ntawm kev txhim kho lipodystrophy yog qhov tsawg heev.

Kev cuam tshuam nrog lwm cov tshuaj:

Cov nyhuv hypoglycemic ntawm Humulin Tsis tu ncua yog txo los ntawm kev tiv thaiv qhov ncauj, corticosteroids, thyroid hormone npaj, thiazide diuretics, diazoxide, tricyclic antidepressants. Hypoglycemic effect ntawm Humulin Tsis tu ncua yog txhim kho los ntawm qhov ncauj hypoglycemic tshuaj, salicylates (piv txwv li, acetylsalicylic acid), sulfonamides, MAO inhibitors, beta-blockers, ethanol thiab ethanol-uas muaj cov tshuaj. Beta-blockers, clonidine, reserpine tuaj yeem npog qhov tsos ntawm cov tsos mob ntawm qog ntshav qab zib. Kev sib txuam tshuaj: kev cuam tshuam los ntawm kev sib xyaw ntawm tib neeg cov tshuaj insulin nrog tsiaj insulin lossis tib neeg insulin tsim los ntawm lwm cov tuam ntxhab tsis tau kawm.

Hnub tas sij hawm: 2 xyoos

Cov mob uas faib tawm los ntawm cov khw muag tshuaj: los ntawm tshuaj

Chaw tsim tshuaj paus: Eli Lilly East S.A., Switzerland

Daim ntawv tso tawm

Nws yog ib qho tseem ceeb kom nco ntsoov tias cov tshuaj nquag hauv tshuaj yog tib neeg biosynthetic insulin. Cov tshuaj tau tso tawm hauv daim ntawv ntawm kev ncua rau kev txhaj tshuaj thiab cov tshuaj tshwj xeeb rau kev txhaj tshuaj. Cov hom no tuaj yeem muaj ob qho tib si rau hauv daim cartridges, thiab hauv hwj.

Tshuaj insulin Humulin N

Chaw tsim tshuaj paus

Ua ntej koj yuav tsum xyuas seb leej twg pom cov insulin? Txoj kev kho rau cov neeg uas muaj ob hom ntshav qab zib tsis tuaj yeem ua tiav yam tsis muaj tib neeg mob insulin. Nws yog qhov xav tau txhawm rau tswj tau cov concentration ntawm cov piam thaj hauv cov ntshav tsis pub dhau ib qho.

Ib qho tshuaj ntxiv yog siv los txhim kho cov mob ntawm tus neeg mob nrog tus mob no. Raws li rau kev tsim cov teb chaws, feem ntau muaj peb lossis plaub ntawm lawv. Txij li muaj ob peb hom tshuaj no, lawv txhua tus yog tsim nyob hauv ntau lub teb chaws.

Lub sijhawm no, cov tshuaj hauv qab no hauv nqe lus nug tau nthuav tawm hauv tsev muag tshuaj:

1. Humulin NPH (Tebchaws Asmeskas, Fabkis),
2. Humulin MZ (Fabkis),
3. Humulin L (Tebchaws Asmeskas),
4. Humulin Tsis Txaus (Fabkis),
5. Humulin M2 20/80 (Tebchaws Asmeskas).

Tag nrho cov saum toj no insulin npaj (pancreatic hormone) muaj lub zog hypoglycemic (hypoglycemic) zoo. Cov tshuaj tau tsim tawm los ntawm cov tib neeg cov tshuaj tua hluav taws xob engineering.

Kev ua haujlwm tseem ceeb ntawm Humulin yog txhawm rau txo qis dua ntawm cov piam thaj hauv ntshav cov ntshav. Yog li, cov tshuaj muab kev noj qab haus huv los ntawm cov piam thaj los ntawm cov ntaub so ntswg cov qauv thiab suav nrog nws hauv cov txheej txheem hauv kev zom zaub mov uas tshwm sim hauv cov keeb ntawm lub cev.

Ua raws li cov txheej txheem ntawm kev npaj thiab kev ua cov txheej txheem, txhua qhov insulin nws muaj nws tus kheej tshwj xeeb, uas tseem coj mus rau hauv qhov kev xaiv tsa ntawm kev kho tshwj xeeb. Ntxiv nrog rau qhov tseem ceeb tivthaiv (insulin, ntsuas hauv thoob ntiaj teb - ME), txhua yam tshuaj suav nrog cov khoom sib txuas ntxiv ntawm cov khoom neeg tsim.

Raws li txoj cai, cov khoom xyaw xws li protamine sulfate, phenol, zinc chloride, glycerin, metacresol, sodium hydrogen phosphate, sodium hydroxide, hydrochloric acid, dej rau kev txhaj tshuaj thiab lwm tus tuaj yeem suav nrog txhua hom Humulin.

Cov tshuaj no pabcuam kom ua tiav qhov tshwm sim zoo los ntawm kev kho. Qhov no yog vim nws muaj peev xwm los ua kom tiav lossis tsis muaj ib feem ntawm qhov cuam tshuam ntawm cov tshuaj insulin.

Nws yog ib qho tseem ceeb uas yuav tsum nco ntsoov tias cov tshuaj no yuav tsum yog kho los ntawm tus kws kho endocrinologist nkaus xwb. Tom qab, thaum qhov kev mob maj nrawm tshwm sim, tsuas yog tus kws kho mob yuav tsum cuam tshuam nrog cov tshuaj kom ntau.

Feem ntau qhov teem sij hawm ntawm insulin hu ua Humulin yog lub neej ntev. Xws li lub sijhawm ntev, nws tau sau tseg nyob rau hauv muaj cov mob ntshav qab zib hom 1 mellitus.

Hauv qee qhov xwm txheej (nrog cov kab mob concomitant tshwm sim nyob rau hauv ib qho kev mob lossis mob ntev, nrog rau muaj qhov tsis zoo ntawm cov mob ntshav qab zib uas muaj mob ntawm hom ob), nws raug nquahu kom siv cov chav kawm ntawm kev kho mob sib txawv.

Tsis txhob hnov ​​qab tias mob ntshav qab zib xav tau kev teem sijhawm ntawm cov tshuaj tua kabmob (pancreatic).

Yog vim li ntawd qhov kev tsis lees txais nws yuav ua rau muaj kev cuam tshuam tsis zoo rau tib neeg kev noj qab haus huv.

Tam sim no, qhov siv tau ntau hauv qhov no muaj xws li hom tshuaj xws li Humulin Tsis tu ncua thiab Humulin NPH.

Nyob ntawm ntau yam, cov tshuaj Humulin tuaj yeem muas tau hauv daim ntawv no:

1. NPHCov. Muaj raws li qhov muab ncua rau kev tswj hwm subcutaneous, 100 IU / ml. Nws yog ntim rau hauv 10 ml lub raj mis hauv lub khob nruab nrab. Txhua ntawm lawv tau ntim hauv thawv ntawv thawv. Daim ntawv ntawm cov tshuaj no tseem tau ntim rau hauv 3 ml cartridges ntawm cov iav zoo sib xws. Tsib ntawm cov no tau muab tso rau hauv lub hlwv. Txhua ntawm lawv haum hauv pob tshwj xeeb,
2. MHCov. Nws muaj nyob rau hauv cov ntawv tso tawm hauv qab no: kev ncua kev txhaj tshuaj (3 ml) hauv cov ntawv tshwj xeeb, muab ncua kev kawm (10 ml) hauv hwj, txhaj tshuaj tov (3 ml) hauv daim cartridges, tov (10 ml) hauv hwj,
3. LCov. Ncua rau kev txhaj tshuaj 40 IU / ml lossis 100 IU / ml hauv lub raj mis 10 ml, nws tau ntim rau hauv pob ntawv los ntawm cov thawv ntawv,
4. NtxawgCov. Ib yam li cov dhau los, nws tau ua hauv koob tshuaj, 1 ml ntawm cov muaj 40 PIECES lossis 100 PIECES,
5. M2 20/80Cov. Qhov kev txhaj tshuaj rho tawm muaj li ntawm 40 lossis 100 IU / ml recombinant tib neeg cov tshuaj insulin. Cov tshuaj muaj nyob hauv hwj thiab daim cartridges.

Ntshav qab zib yog ntshai ntawm cov tshuaj no, zoo li hluav taws!

Koj tsuas yog xav tau thov ...

Raws li rau tus nqi, txhua qhov txiav txim siab sib txawv ntawm cov tshuaj muaj nws tus nqi.

Yog tias nyob rau hauv ntau dua kom meej, ces tus nqi daim ntawv teev rau Humulin yog raws li nram no:

1. NPH - nyob ntawm qhov muab cov tshuaj, cov nqi nruab nrab yog 200 rubles,
2. MH - tus nqi kwv yees txawv ntawm 300 txog 600 rubles,
3. L - tsis pub dhau 400 rubles,
4. Ntxawg - txog 200 rubles,
5. M2 20/80 - los ntawm 170 rubles.

Txoj kev ntawm daim ntawv thov

Cov tshuaj Humulin feem ntau muab ua haujlwm xws li kev hla lub plab zom mov. Feem ntau yog txhaj tshuaj rau qhov ntswg lossis subcutaneous txhaj tshuaj.

Raws li cov kev cai uas twb muaj lawm, tus neeg mob endocrinologist tus neeg mob yuav tsum tau mus kawm kev qhia tshwj xeeb, piv txwv li, hauv "tsev kawm mob ntshav qab zib".

Ntau npaum li cas ntawm cov tshuaj no xav tau ib hnub, tsuas yog tus kws kho mob uas tuaj koom yuav tsum txiav txim siab. Cov tshuaj tau xaiv yuav sib txawv raws li hom kev tawm dag zog thiab lub cev. Nws yog ib qho tseem ceeb heev uas tus neeg mob ntawm endocrinologist ib txhij tswj theem ntawm glycemia.

Raws li txoj cai, insulin-based tshuaj yuav tsum noj tsis tu ncua. Cov tshuaj no zoo sib xws rau txiv neej thiab poj niam.

Cov kws kho mob hais tias Humulin tuaj yeem siv siv txawm yog menyuam yaus. Yog lawm, yog tias glycemia raug tswj thaum lub sijhawm siv. Cov neeg laus yuav tsum ua tib zoo saib xyuas cov haujlwm ntawm cov plab hnyuv siab rau ntawm qhov tso tawm ntawm lub cev. Raws li txoj cai, cov kws kho mob tau sau ntawv noj tshuaj tsawg dua rau cov neeg mob ntawd.

Thaum cev xeeb tub, cov tshuaj no kuj tseem siv tau. Ntau cov tshuaj raws li cov tshuaj insulin, zoo ib yam rau tib neeg, raug tso cai siv rau kev pub niam mis.

Sab sij huam

Humulin ntawm ntau hom muaj tib lub phiv, uas tau teev nyob rau hauv cov lus qhia rau nws.

Qhov feem ntau yuav yog qhov muaj kev hloov pauv rau tib neeg cov kua dej tuaj yeem ua rau lipodystrophy (hauv thaj chaw uas tau txhaj tshuaj).

Txawm hais tias nyob rau hauv cov neeg mob endocrinologist, tawm tsam keeb kwm ntawm kev siv cov tshuaj no, kev tiv thaiv insulin, kev ua xua, kev txo cov poov tshuaj hauv cov ntshav, thiab qhov muag pom kev tsis zoo yog sau tseg.

Kev ua xua tuaj yeem tshwm sim tsis yog los ntawm lub cev ntawm lub cev nqaij hlav, tab sis los ntawm cov tshuaj ntxiv, yog li, hloov nrog lwm cov tshuaj zoo ib yam li tau tso cai.

Cov Yuav Tsum Muaj

Cov tshuaj hauv cov nqe lus nug yog tsim rau insulin-tiv thaiv thiab tsis-insulin-tiv thaiv ntshav qab zib mellitus.

Nws yog ib qho tseem ceeb uas yuav tau ceev faj heev, tshwj xeeb yog tias muaj kev soj ntsuam ntshav qab zib tsawg (cov piam thaj hauv ntshav tsawg).

Lwm cov tshuaj yog txwv tsis pub siv nyob rau hauv lub xub ntiag ntawm ib tug neeg intolerance (txij li thaum lub tsos ntawm undesirable kev tsis haum yog yuav). Cov kws tshaj lij txwv tsis pub haus cawv thaum kho nrog hom tshuaj insulin no. Qhov no yog vim tias qhov hloov kho tau ntau hauv cov ntshav cov piam thaj tau tshwm sim.

Ua ntej siv, koj yuav tsum xyuam xim rau cov tshuaj uas koj noj lub caij tam sim no. Qee ntawm lawv tsis sib xws nrog Humulin.

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Tsab xov xwm no tshuaj xyuas qhov tshuaj hormones ntawm lub txiav los ntawm cov keeb kwm dag, uas zoo ib yam rau tib neeg insulin - Humulin. Nws yuav tsum tau noj tsuas yog tias nws tau sau tseg los ntawm tus kws kho mob raws kev soj ntsuam.

Kev siv ywj pheej ntawm cov tshuaj no raug cais tawm tag nrho, txij li kev tsis haum lub cev tsis tuaj yeem tshwm sim. Ntxiv rau, cov tshuaj no tsis raug faib hauv cov khw muag tshuaj yam tsis muaj tshuaj los ntawm kws kho mob ntawm tus kheej.

Pharmacodynamics thiab pharmacokinetics

Humulin NPH yog DNA recombinant tib neeg cov kua dej nrog lub sijhawm nruab nrab ntev ntawm kev sib kis, cov nyhuv tseem ceeb ntawm uas yog kev tswj hwm piam thaj metabolismCov. Cov tshuaj tseem qhia tau anabolic ua hauj lwm zoo.

Hauv cov ntaub so ntswg ntawm tib neeg lub cev (tshwj tsis yog lub cev ntawm lub hlwb), insulin Humulin NPH ua rau kev thauj khoom amino acids thiab piam thaj, thiab kuj ceev nrooj cov txheej txheem protein anabolismCov. Nyob rau hauv parallel nyob rau hauv daim siab, cov tshuaj txhawb txoj kev tsim ntawm glycogenlos ntawm piam thajtxhawb nqa qhov hloov pauv ntawm kev ua kom tshaj piam thajhauv roginhibits gluconeogenesis.

Qhov pib ntawm insulin kev ua yeeb yam Humulin NPH raug pom 60 feeb tom qab kev tswj hwm, nrog kev ua haujlwm ntau tshaj plaws hauv lub sijhawm txij li 2 mus rau 8 teev thiab ntev li ntawm kev ua hauv 18-20 teev.

Saib xyuas ib tug neeg sib txawv hauv qhov ua tau zoo tshuaj insulinnyob ntawm seb qhov kev xaiv ntawm koob tshuaj, chaw txhaj tshuaj, nrog rau qhov ua si lub cev ntawm tus neeg mob.

Kev ntsuas rau siv

Cov tshuaj Humulin NPH tau qhia rau kev siv nrog:

• thawj kuaj mob mob ntshav qab zib,
• mob ntshav qab zibnyob rau hauv cov ntaub ntawv ntawm kev qhia rau kev teem caij tshuaj insulin,
• cev xeeb tubnyob rau tom qab non-insulin-mob ntshav qab zib mellitus (hom 2).

Sab sij huam

Cov kev mob tshwm sim loj yog ntshav qog, uas qhov xwm txheej mob hnyav yuav ua rau tsis nco qab thiab txawm tuag (tsis tshua muaj).

Muaj kuj yog qhov tsawg tsawg ntawm kev tsim lipodystrophy.

Kev ua xua uas ua rau muaj txiaj ntsig:

Ua xua tshwm sim ntawm ib qho chaw nyob hauv nroog:

• o tuajlossis khaushauv thaj tsam ntawm kev txhaj tshuaj (feem ntau tso tseg li ntawm ob peb lub lis piam),
• kev hyperemia.

Cov lus qhia rau kev siv Humulin NPH

Qhov ntau npaum ntawm Humulin NPH raug xaiv ib tus zuj zus, raws li theem ntawm txhauvtus neeg mob.

Kev txhaj tshuaj rau ntshav ntawm Humulin NPH raug txwv!

Lub emulsion yuav tsum tau ua haujlwm sc, qee kis, IM kev tso cai raug tso cai. Kev tswj hwm tus neeg mob yog nqa hauv plab plab, xub pwg, pob tw lossis ncej puab. Qhov chaw txhaj tshuaj yuav tsum tau hloov chaw kom thiaj li 30 hnub tsis pub ntau tshaj ib qho kev txhaj tshuaj rau hauv ib qho chaw.

SC kev txhaj tshuaj yuav tsum muaj kev txawj ntse ntawm kev tswj hwm thiab kev ceev faj. Nws yog ib qho tsim nyog kom tsis txhob tau txais cov koob txhaj tshuaj rau hauv cov hlab ntshav, tsis txhob zaws mus rau qhov chaw txhaj tshuaj, thiab tseem tuaj yeem ua rau cov cuab yeej coj los tswj cov tshuaj kom raug.

Npaj thiab tswj hwm ntawm Humulin NPH

Nrog tus aim cov tshuaj insulin, ua ntej siv, lub vials thiab daim cartridges ntawm kev npaj Humulin NPH raug pom zoo kom muab cov ntawv no 10 npaug rau hauv koj xib teg ntawm koj txhais tes thiab co tib lub sijhawm qub (tig mus txog 180 °) kom txog rau thaum qhov kev npaj kis tau tus mob ntawm cov xim tsis huv uas nyob ze rau mis lossis kua homogeneous. Tuav cov tshuaj kom nruj yuav tsum tsis yog, vim tias ua npuas dej ua txoj hauv kev no tuaj yeem cuam tshuam txoj kev xaiv qhov tseeb.

Vials thiab cartridges yuav tsum tau kuaj nrog kev saib xyuas tshwj xeeb. Zam kev siv tshuaj insulinnrog txo cov nplaim ya los yog dawb hais kom haum rau cov phab ntsa lossis hauv qab ntawm lub hwj, ua rau pom kev xav ntawm tus qauv khov.

Qhov tsim ntawm daim cartridge tsis pub nws cov ntsiab lus sib xyaw nrog lwm tus tshuaj insulin, as Well as refilling cartridge nws tus kheej.

Thaum siv vials, lub emulsion sau rau hauv uas cov tshuaj insulin, uas nyob rau hauv ntim sib raug rau lub tswv yim tshuaj insulin(piv txwv li 100 IU / 1 ml tshuaj insulin= 1 ml syringe) thiab muab rau hauv raws li cov lus pom zoo ntawm tus kws kho mob.

Thaum siv daim cartridges, nws yog qhov yuav tsum tau ua raws li cov lus qhia ntawm cov chaw tsim tshuaj tiv thaiv rau kev txhim kho lawv, txuas lub koob, thiab tseem yuav siv cov tshuaj insulin, piv txwv li cov lus qhia rau Humulin NPH hauv cwj mem ceev txhaj tshuaj.

Tam sim tom qab txhaj tshuaj, siv lub hau sab nraud ntawm rab koob, tshem tawm rab koob nws tus kheej thiab rhuav nws kom zoo, tom qab ntawd kaw qhov kov nrog lub hau. Cov txheej txheem no muab cov tshuaj tiv thaiv kab mob ntxiv, tiv thaiv huab cua nkag, tiv thaiv cov tshuaj ntawm cov tshuaj thiab nws qhov txhaws.

Koob thiab rab koob yuav tsum tsis txhob rov siv los yog siv lwm tus neeg. Vials thiab cartridges siv ib zaug kom txog thaum cov tshuaj tiav, thiab tom qab ntawd muab pov tseg.

Tej zaum qhov qhia txog Humulin NPH hauv kev sib xyaw nrog Humulin Tsis tu ncuaCov. Vim li cas, txhawm rau tiv thaiv kev nkag mus rau hauv lub raj mis tshuaj insulinntev dua kev txiav txim, thawj tus hu mus rau hauv cov phwj tshuaj insulinkev txiav txim luv. Txoj kev sib xyaw no yog pom zoo kom hais qhia tam sim tom qab tov. Rau qhov tseeb qhov ntau npaum ntawm ob tshuaj insulintuaj yeem siv cov koob txhaj sib txawv.

Noj ntau dhau

Xws li, tsis muaj qhov tshwj xeeb tshaj plaws txog Humulin NPH. Cov tsos mob yog suav tias yog qhov tsos mob. ntshav qognrog nrog nce hwsnkees tachycardiamob taub hau pallor daim tawv nqaij integument tshee, tsis meej pemntuav.

Muaj qee kis, cov tsos mob tshwm sim ua ntej hypoglycemia (mob ntshav qab zib ntev lossis nws txoj kev tswj nruj) tuaj yeem hloov pauv.

Neej Neeg ntshav qogme me, feem ntau tso tseg los ntawm qhov ncauj tswj hwm qab ziblossis piam thaj(dextrose) Hauv lub neej yav tom ntej, koj yuav tau kho kho kev noj haus, tshuaj ntau ntau tshuaj insulinlossis kev tawm dag zog.

Kho kom haum ntshav qogmob hnyav no yog nqa los ntawm SC lossis hauv / m txhaj tshuaj glucagon, nrog kev tswj hwm qhov ncauj ntxiv carbohydrates.

Cov cim ntawm loj ntshav qogtuaj yeem coj nrog coma, cov leeg mob hlwb lossis spasmsuas yog localized los ntawm iv txhaj tshuaj nyob zoo cov piam thajs (dextrose) lossis s / c lossis hauv / m kev qhia glucagonCov. Yav tom ntej, txhawm rau tiv thaiv kom tsis txhob rov mob tshwm sim, cov zaub mov nplua nuj carbohydrates.

Kev sib txuam

Hypoglycemic hauj lwm zoo ntawm Humulin NPH txo qis dua nrog kev siv sib xyaw tshuaj tiv thaiv qhov ncaujcov thyroid hormones glucocorticoids, thiazide diureticstricyclic tshuaj tiv thaiv kab mob, Diazoxide.

Daim Ntawv Tso Npe Ua Ke ethanolcov tshuaj hypoglycemic (qhov ncauj), salicylatesMAO inhibitors sulfonamides, beta blockers txhim kho cov teebmeem hypoglycemic ntawm Humulin NPH.

Cov lus qhia tshwj xeeb

Txiav txim siab txog qhov xav tau hloov tus neeg mob rau lwm cov tshuaj lossis hom tshuaj insulin tsuas yog ua tau kws kho mob. Qhov kev hloov no yuav tsum muaj nyob rau hauv kev tswj hwm nruj ntawm tus neeg mob lub sijhawm.

Hom pauv cov tshuaj insulin(Ntxawg, M3lwm yam), nws cov hom koom tes (tib neeg, nqaij npuas, analog) lossis txujci ntau lawm (tsiajkeeb kwm los yog DNA recombinant) tej zaum yuav tau kho kom haum ntau dua, ob zaug thaum thawj zaug muab tshuaj thiab thaum kho, maj mam dhau ob peb vas thiv lossis hli

Cov tshuaj insulinqhov tos seb yuav txo nrog lub raum tsis ua hauj lwmpituitary caj pas cov qog adrenallub qog ua haujlwm mob siab.

Ntawm kev ntxhov siab thiab nrog qee cov pathologies, tej zaum yuav muaj qhov xav tau nce ntxiv tshuaj insulin.

Qee zaum cov tshuaj kho kom haum yog qhov tsim nyog thaum hloov cov pluas nojlossis nce kev siv lub cev.

Hauv qee cov neeg mob, yog tias siv tib neeg cov insulincov tsos mob ua ntej ntshav qogyuav txawv ntawm cov thaum siv tsiaj cov insulin lossis tsis tau hais tshaj.

Normalization ntawm ntshav piam thajvim mob siab heev tshuaj insulinua rau muaj kev ploj tag nrho los yog qee qhov kev qhia paub ntshav qogyam uas koj yuav tsum qhia rau tus neeg mob.

Cov tsos mob ntawm qhov pib ntshav qogtej zaum yuav smoothed los sis hloov thaum uas siv parallel beta blockers, uas mob ntshav qab zib neuropathylossis ntevmob ntshav qab zib mellitus.

Hauv qee kis, hauv zos ua xuakev nthuav qhia yuav tsim rau cov laj thawj tsis cuam tshuam nrog lub txiaj ntsig ntawm cov tshuaj (piv txwv li, daim tawv nqaij voos vim yog siv cov tshuaj ntxuav kab mob los yog txhaj tshuaj tsis raws cai).

Tsis tshua muaj, kev tsis sib thooj rau txoj kab ke tuaj yeem xav tau kev kho mob sai sai (kev coj ua desensitizationlossis insulin hloov).

Vim yog cov tsos mob tshwm sim ntshav qogtag nrho cov kev ceev faj yuav tsum tau ua thaum ua haujlwm tsis zoo thiab tsav tsheb.

• Insulin-Ferein xwm ceev,
• Monotard HM,
• Tshuaj insulin-Ferein ChSP,
• Monotard MC,
• Neej Neeg B,
• Pensulin SS.

• Vozulim-N,
• Biosulin N,
• Humulin M3,
• Gansulin N,
• Insuman Bazal GT,
• Gensulin N,
• Humulin Tsis tu ncua,
• Kev pov hwm NPH,
• Tshuaj yaug NPH,
• Protafan HM,
• Humodar B 100 Hav dej.

Cov sijhawm teem sijhawm ntawm kev tswj hwm, ntau npaum li cas thiab cov naj npawb ntawm cov kev txhaj tshuaj yog tus kheej tau txiav txim siab los ntawm tus kws kho mob uas koom nrog, ua raws li qee qhov xav tau tshwj xeeb ntawm tus neeg mob.

Hauv cev xeeb tub (thiab lactation)

Cov neeg mob nrog mob ntshav qab zibqhia koj tus kws kho mob txog kev npaj lossis tshwm sim cev xeeb tub, raws li ib txwm muaj, qhov xav tau tshuaj insulintxo qis hauv thawj peb lub hlis thiab nce ntxiv hauv qib thib ob thiab thib peb (kev teem sijhawm tuaj yeem tsim nyog tshuaj insulinnrog kev sib txuas ntxiv koob).

Tsis tas li, kev noj haus kev noj haus thiab / lossis kev muab tshuaj rau noj nyob rau lub sijhawm kev pub mis.

Thaum xaiv tshuaj insulintus kws kho mob yuav tsum ntsuas tus neeg mob lub mob ntawm txhua sab ntawv thiab xaiv cov tshuaj uas haum rau tus neeg mob tshwj xeeb no.

Hauv qhov no, cov tshuaj Humulin NPH qhia pom cov txiaj ntsig kho tau zoo thiab tuaj yeem siv rau lub sijhawm ntev.