Rinsulin R - cov lus qhia ntawm kev siv > Kev khomob thiab kev tiv thaiv

Cov Tshuaj Hauv Tshuaj

Rinsulin P yog tib neeg cov kua dej tau txais los siv siv thev naus laus zis DNA thev naus laus zis. Luv luv insulin. Nws cuam tshuam nrog kev lees paub tshwj xeeb rau sab nraud cytoplasmic membrane ntawm cov hlwb thiab tsim cov txheej txheem insulin-receptor complex uas txhawb cov txheej txheem intracellular, suav nrog cov synthesis ntawm ntau cov enzymes tseem ceeb (hexokinase, pyruvate kinase, glycogen synthase, thiab lwm yam). Txo cov ntshav qabzib yog tshwm sim los ntawm kev nce ntxiv hauv nws txoj kev thauj mus los hauv lub cev, qhov ntau dua nqus thiab assimilation ntawm cov ntaub so ntswg, txhawb kev lipogenesis, glycogenogenesis, txo tus nqi ntawm cov piam thaj los ntawm lub siab, thiab lwm yam.
Lub sijhawm ntawm cov kev ua ntawm insulin npaj feem ntau vim yog tus nqi ntawm kev nqus, uas nyob ntawm ntau yam (piv txwv li, ntawm koob tshuaj, txoj kev thiab qhov chaw ntawm cov thawj coj), thiab yog li cov ntaub ntawv ntawm kev ua ntawm insulin yog raug rau qhov txawv txav, ob leeg hauv cov neeg sib txawv thiab tib tus neeg. Qhov nruab nrab, tom qab kev tswjfwm subcutaneous, Rinsulin P pib ua tom qab 30 feeb, qhov ua haujlwm siab tshaj plaws tsim tawm ntawm 1 mus rau 3 teev, qhov ua haujlwm ntev yog 8 teev.

Cov Tshuaj Pharmacokinetics
Kev ua tiav ntawm kev nqus thiab pib ntawm cov nyhuv ntawm cov tshuaj insulin nyob ntawm txoj hauv kev ntawm kev tswj hwm (subcutaneously, intramuscularly, mob siab), qhov chaw tswj hwm (mob plab, ncej puab, pob tw), koob tshuaj (ntim ntawm txhaj tshuaj insulin), cov tshuaj insulin nyob rau hauv cov tshuaj, thiab lwm yam Nws raug faib tsis ncaj thoob plaws cov ntaub so ntswg, tsis nkag mus los ntawm placental barrier thiab ua kua mis. Nws yog rhuav tshem los ntawm insulinase feem ntau hauv daim siab thiab lub raum. Qhov kev tshem tawm ib nrab-lub neej ua rau ob peb feeb. Nws yog tawm los ntawm lub raum (30-80%).

Kev ntsuas rau siv

Yam 1 ntshav qab zib
Hom 2 mob ntshav qab zib mellitus: theem ntawm kev tawm tsam ntawm qhov ncauj hypoglycemic, ib nrab tsis kam rau cov tshuaj no (thaum kho sib xyaw), cov kab mob sib kis
Hom Ntshav Qab Zib 2 hauv cov poj niam cev xeeb tub
Kev mob xwm txheej ceev hauv cov neeg mob ntshav qab zib mellitus nrog kev decompensation ntawm carbohydrate metabolism

Tsuas tshuaj thiab tswj hwm

Dosage regimen and route ntawm cov thawj coj

Cov tshuaj yog npaj rau subcutaneous, intramuscular thiab leeg tswj kev siv tshuaj.
Qhov koob tshuaj thiab txoj hauv kev ntawm kev tswj hwm tshuaj yog txiav txim los ntawm tus kws kho mob ib leeg zuj zus hauv txhua kis raws li cov concentration ntawm cov piam thaj hauv cov ntshav.
Qhov nruab nrab, cov tshuaj txhua hnub ntawm cov tshuaj yog li 0.5 mus rau 1 IU / kg lub cev qhov hnyav (nyob ntawm tus neeg qhov yam ntxwv ntawm tus neeg mob thiab qhov siab ntawm cov ntshav qab zib).
Cov tshuaj tau muab noj 30 feeb ua ntej noj mov lossis noj khoom txom ncauj uas muaj cov carbohydrates.
Qhov kub ntawm cov tshuaj insulin yuav tsum nyob ntawm chav sov. Nrog rau cov tshuaj monotherapy nrog rau cov tshuaj, ntau zaus ntawm kev tswj hwm yog 3 zaug hauv ib hnub (yog tias tsim nyog, txog li 5-6 zaug hauv ib hnub). Hauv kev noj tshuaj txhua hnub ntau dua 0.6 IU / kg, cov tshuaj yuav tsum tau muab nyob rau hauv daim ntawv ntawm 2 lossis ntau dua kev txhaj tshuaj nyob rau ntau qhov chaw ntawm lub cev. Cov tshuaj feem ntau yog hno subcutaneously rau hauv ntu pem hauv ntej phab ntsa. Qhov hno tuaj yeem tuaj yeem ua tau nyob hauv tus ncej, pob tw lossis xub pwg hauv qhov projection ntawm cov leeg deltoid.
Nws yog ib qho tsim nyog yuav tsum hloov chaw txhaj tshuaj nyob rau thaj tsam anatomical thiaj li tiv thaiv kev txhim kho ntawm lipo-dystrophy. Nrog kev tswj hwm ntawm cov ntshav dej, yuav tsum tau saib xyuas kom tsis txhob nkag rau cov ntshav thaum lub sijhawm txhaj. Tom qab txhaj tshuaj, qhov chaw txhaj tshuaj yuav tsum tsis txhob zaws. Cov neeg mob yuav tsum tau kawm paub txog kev siv tshuaj insulin kom zoo.
Intramuscularly thiab intravenously, cov tshuaj tuaj yeem raug tswj hwm tsuas yog nyob hauv kev saib xyuas ntawm kws kho mob.
Vials tsuas yog siv tau yog tias lawv cov ntsiab lus yog ntshiab, tsis muaj kua uas tsis muaj qhov pom pom. Koj tuaj yeem siv tsis tau cov tshuaj yog tias muaj qee qhov tshwm sim hauv kev daws teeb meem. Rinsulin ® P yog cov tshuaj insulin luv luv thiab feem ntau yog siv ua ke nrog cov kua dej nruab nrab (Rinsulin ® NPH).
Nws yog ib qho ua tau khaws cov tshuaj rau hauv kev siv ntawm chav sov (ntawm 15 txog 25 ° C) tsis pub dhau 28 hnub.

Sab sij huam

Vim tias muaj qhov tshwm sim ntawm cov metabolism hauv carbohydrate: Cov ntshav qog ntshav siab (pallor ntawm daim tawv nqaij, nce tawm hws, palpitations, tshee tshee, tshee, tshaib plab, ntxhov siab, teeb tsa ntawm lub qhov ncauj qhov ntswg, tsis muaj zog, mob taub hau, kiv taub hau, tsis pom kev zoo nkauj). Kev mob ntshav qog ntshav qis tuaj yeem ua rau txhim kho kev mob hypoglycemic coma.
Kev ua xua tsis haum: daim tawv nqaij ua pob, Quincke's edema, tshuaj tiv thaiv anaphylactic.
Kev tiv thaiv hauv zos: hyperemia, o thiab khaus ntawm qhov chaw txhaj tshuaj, nrog rau siv sijhawm ntev - lipodystrophy ntawm thaj chaw txhaj tshuaj.
Lwm yam: edema, kev ua haujlwm txo qis hauv qhov pom tseeb (feem ntau thaum pib kho).
Yog hais tias tus neeg mob tau sau tseg kev txhim kho hypoglycemia lossis tau hnov mob tsis nco qab, nws yuav tsum qhia rau tus kws kho mob sai.
Yog tias muaj lwm cov kev mob tshwm sim uas tsis tau piav los saum no tau txheeb xyuas, tus neeg mob koj kuj yuav tsum sab laj ib tus kws kho mob.

Cov lus qhia tshwj xeeb

Cov kev ceev faj rau kev siv

Tawm tsam tom qab ntawm cov tshuaj insulin, kev tshuaj xyuas cov ntshav qabzib hauv siab yog qhov tsim nyog.
Cov laj thawj ntawm cov ntshav qog ntshav ntshav ntxiv rau kev noj tshuaj insulin ntau tshaj tuaj yeem yog: hloov tshuaj, hla zaub mov, ntuav, raws plab, ua kom lub cev muaj zog ntau ntxiv, cov kab mob uas txo qis qhov xav tau rau insulin (kev mob siab rau lub siab thiab lub raum kev ua haujlwm, kev ua haujlwm ntawm adrenal cortex, pituitary lossis thyroid caj pas), hloov chaw txhaj tshuaj, ntxiv rau kev cuam tshuam nrog rau lwm cov tshuaj.
Kev noj tshuaj tsis yog lossis cuam tshuam rau hauv cov tshuaj insulin, tshwj xeeb tshaj yog nyob rau cov neeg mob ntshav qab zib hom 1, tuaj yeem ua rau mob hyperglycemia. Feem ntau thawj cov tsos mob ntawm hyperglycemia pib maj mam dhau ob peb teev lossis hnub. Cov no suav nrog kev nqhis dej, ntxiv tso zis, xeev ntuav, ntuav, kiv taub hau, liab thiab ntawm daim tawv nqaij, qhov ncauj qhuav, tsis qab los, tsis hnov ntxhiab ntawm cov acetone hauv cov pa tawm. Yog tias tsis kho, hyperglycemia hauv ntshav qab zib hom 1 tuaj yeem ua rau muaj kev tiv thaiv cov mob ntshav qab zib ketoacidosis.
Cov koob tshuaj insulin yuav tsum raug kho rau kev ua haujlwm ntawm cov thyroid tsis zoo, Addison's disease, hypopituitarism, ua rau lub siab thiab lub raum tsis ua haujlwm thiab mob ntshav qab zib hauv cov neeg muaj hnub nyoog 65 xyoos.
Kev kho tshuaj ntawm cov tshuaj insulin kuj tseem xav tau yog tias tus neeg mob nce ntxiv ntawm kev ua haujlwm lub cev lossis hloov cov zaub mov li qub.
Cov kab mob sib xyaw tshwj xeeb, tshwj xeeb tshaj yog kis mob thiab cov kab mob nrog kub taub hau, nce ntxiv qhov xav tau ntawm insulin.
Kev hloov chaw ntawm tus neeg mob mus rau ib hom tshiab ntawm insulin lossis kev tsim tshuaj insulin ntawm lwm qhov chaw tsim khoom yuav tsum tau ua nyob ntawm kev saib xyuas ntawm kws kho mob.
Vim tias muaj qhov ua rau nag lossis daus hauv qee qhov ntsuas, kev siv yeeb tshuaj hauv cov tshuaj insulin tsis pom zoo.

Muaj feem xyuam rau kev muaj peev xwm tsav tsheb thiab cov txheej txheem

Hauv kev sib txuas nrog lub hom phiaj tseem ceeb ntawm insulin, qhov kev hloov pauv ntawm nws hom, lossis nyob rau ntawm lub cev lossis lub cev kev ntxhov siab tseem ceeb, nws yuav ua rau lub peev xwm tsav lub tsheb lossis ntau cov txav mus los, nrog rau kev koom tes rau lwm yam kev phom sij uas xav tau nce siab thiab ceev.

Chaw tsim tshuaj paus

Chaw nyob ntawm cov chaw ntau lawm:

142279, cheeb tsam Moscow, Serpukhov koog tsev kawm ntawv, r.p. Obolensk, lub tsev 82, p. 4.
142279, cheeb tsam Moscow, Serpukhov koog tsev kawm ntawv, pos. Obolensk, lub tsev 83, lit. AAN.

Cov koom haum lees txais:

GEROPHARM-Bio OJSC
142279, cheeb tsam Moscow, Serpukhov koog tsev kawm ntawv, r.p. Obolensk, lub tsev 82, p. 4

Cov lus qhia yuav muab rau tus neeg mob

Koj tuaj yeem siv tsis tau cov tshuaj yog tias muaj qee qhov tshwm sim hauv kev daws teeb meem.
Cov txheej txheem txhaj tshuaj rau insulin hauv vials

Yog tias tus neeg mob siv tsuas yog ib hom tshuaj insulin

Sanitize roj hmab daim nyias nyias ntawm lub vial
Kos cov cua hauv lub koob txhaj tshuaj hauv lub ntim uas yuav haum rau qhov xav tau ntawm cov tshuaj insulin. Tshaj tawm huab cua rau hauv lub vial ntawm insulin.
Tig lub khob nrog lub taub hau ntxeev tiaj thiab kos cov koob xav tau ntawm cov tshuaj insulin rau hauv cov phwj. Tshem tawm cov koob txhaj tshuaj ntawm lub khob thiab tshem tawm cov cua los ntawm kab mob. Kuaj seb qhov tshuaj insulin puas raug.
Hno tam sim.

Yog tias tus neeg mob xav tau ob hom tshuaj insulin sib xyaw

Txom nyem qhov roj hmab nyias nyias ntawm lub vials.
Tam sim ntawv ua ntej hu, yob ib qho viav vias insulin ntev ntev ("huab") nruab nrab ntawm koj xib teg kom txog thaum cov tshuaj insulin zuj zus thiab dawb.
Sau cov cua mus rau hauv cov phwj hauv qhov ntim coj los ntsuas rau ntawm cov tshuaj huab insulin. Ntxig huab cua rau hauv cov vias insulin vial thiab tshem tawm cov koob ntawm lub vial.
Kos cua rau hauv lub qhov ntswg hauv qhov ntau npaum li cas ntawm cov koob tshuaj insulin luv luv ("pob tshab"). Tshaj tawm cov huab cua mus rau hauv lub raj mis kom paub meej ntawm insulin. Tig lub raj mis nrog cov koob txhaj tshuaj ib sab hauv qab thiab hu lub koob xav tau ntawm "ntshiab" insulin. Tshem tawm cov koob tawm thiab tshem tawm cov cua ntawm lub koob txhaj tshuaj. Kuaj qhov tseeb.
Ntxig lub koob rau hauv lub khob uas siv cov insulin “pos huab”, tig lub khob nrog lub koob txhaj tshuaj kaws sab hauv thiab ntaus lub koob xav kom tau. Tshem tawm cov cua hauv lub koob txhaj tshuaj thiab xyuas seb qhov koob tshuaj muaj tseeb li cas. ចាក់ cov tshuaj insulin sib tov tam sim ntawd.
Txhua zaus yuav tsum siv tshuaj insulin hauv tib theem zuj zus raws li tau piav qhia saum toj no.

Cov txheej txheem kev txhaj tshuaj

Nws yog ib qho tsim nyog yuav tsum tau ntxuav lub thaj tsam ntawm daim tawv nqaij uas qhov tshuaj insulin yuav raug.
Nrog rau ob tug ntiv tes, sau cov kab ntawm daim tawv nqaij, ntxig rab koob rau hauv lub hauv paus ntawm quav ntawm kaum ntawm 45 degrees, thiab txhaj tshuaj insulin hauv qab daim tawv nqaij.
Tom qab txhaj, koob yuav tsum nyob twj ywm hauv qab daim tawv nqaij tsawg kawg 6 vib nas this, txhawm rau xyuas kom meej tias cov insulin nkag.
Yog tias cov ntshav pom ntawm qhov chaw txhaj tshuaj tom qab tshem tawm rab koob, maj mam nyem qhov chaw txhaj tshuaj nrog qhov qhwv nrog qhov ntub dej uas muaj tshuaj tua kab mob (xws li dej cawv).
Nws yog ib qho tsim nyog yuav tsum hloov chaw txhaj tshuaj.

Cov ntaub ntawv dav dav

Cov tshuaj yog npaj los txo cov concentration ntawm qab zib. Nws lub ntsiab tivthaiv yog tib neeg cov kua dej.

Ntxiv rau nws, cov tshuaj muaj pes tsawg leeg suav nrog:

Rosinsulin yog muaj raws li kev txhaj tshuaj. Nws tsis muaj xim thiab ntxhiab tsw.

Cov tshuaj muaj ob peb ntau yam:

P - nws yog tus cwj pwm los ntawm lub nrawm ntawm kis tau.
C - nws qhov kev txiav txim ntawm lub sijhawm nruab nrab.
M - lwm lub npe - Rosinsulin sib tov 30-70. Nws muab sib xyaw ua ke ob qho: soluble insulin (30%) thiab isophan insulin (70%).

Hauv qhov no, cov tshuaj tau teev tseg muaj qee qhov sib txawv, txawm tias feem ntau cov ntsiab cai ntawm lawv qhov kev txiav txim yog qhov zoo ib yam.

Cov tshuaj yuav tsum tsuas yog siv raws li kws kho mob tau hais, tsuas yog los ntawm nws koj tuaj yeem tau txais cov lus qhia kom raug. Yog tsis muaj nws, cov tshuaj no tuaj yeem tsim kev phom sij txawm tias cov neeg mob uas nws tau qhia.

Tso tawm daim ntawv thiab muaj pes tsawg leeg

“Rosinsulin” hais txog cov tshuaj hypoglycemic. Nyob ntawm qhov nrawm ntawm kev kis tau tshuaj thiab lub sijhawm, muaj:

"Rosinsulin S" yog hais txog cov tshuaj nruab nrab,
"Rosinsulin R" - luv luv,
Rosinsulin M yog kev sib koom ua ke.

Ib yam tshuaj yog insulin, tau txais tshwj xeeb los ntawm tib neeg lub cev los ntawm kev hloov DNA. Raws li tau hais hauv cov lus qhia rau kev siv Rosinsulin C, lub hauv paus ntsiab lus ntawm kev ua yog raws li kev sib cuam tshuam ntawm cov tshuaj tseem ceeb ntawm cov tshuaj nrog cov hlwb. Raws li qhov tshwm sim ntawm qhov no, insulin complex tsim.

Cov tshuaj yog ncua kev kawm ntawv lub hom phiaj rau subcutaneous thawj coj. Nws cov nyhuv yog qhov tseem ceeb vim yog cov ntsiab lus ntawm insulin-isophan hauv cov lus muaj. Nov yog tshuaj dawb nrog qhov zas daj. Yog tias nws tsis shaken, ces nws muab faib rau cov kua roj ntshiab thiab cov kua muag. Tias yog vim li cas raws li cov lus qhia, ua ntej qhia cov tshuaj koj xav tau co me ntsis.

Cov tshuaj no muaj tus nqi zoo nkauj. Cov lus qhia rau kev siv "Rosinsulin R" qhia tias cov cuab yeej no yog soluble luv-ua yeeb yam insulin. Nws cuam tshuam tau yooj yim heev nrog lub tshwj xeeb txais ntawm lub ntsej muag cell, thaum tsim cov insulin receptor complex.

Thaum lub sij hawm kho nrog cov tshuaj no, cov suab thaj nyob hauv cov roj ntsha thiab lub siab ua haujlwm ntau ntxiv. Lub ntsiab tseem ceeb nkag mus rau cov leeg hlwb, txhawb nqa cov haujlwm ntawm cov txheej txheem intracellular.

Vim tias muaj cov protein ua ke ua ke ntau zog, cov concentration ntawm cov piam thaj hauv cov ntshav thiab tawg ntawm glycogen yog txo qis. Tom qab txhaj, cov nyhuv kho pib rau hauv 30 feeb. Lub sijhawm ua haujlwm ntawm ib koob tshuaj yog kwv yees li 8 teev. Tus nqi feem ntau nyob ntawm qhov ntau npaum li cas, txoj kev thiab thaj chaw ntawm kev coj.

Cov tshuaj "Rosinsulin C" yog nthuav tawm hauv daim ntawv ntawm isophane nrog lub sijhawm nruab nrab ntawm kev nqis tes ua. Cov tshuaj pab txo qis cov ntshav qabzib hauv cov ntshav, ua rau nws nqus los ntawm cov nqaij mos. Qhov no txo cov nqi ntawm cov piam thaj los ntawm lub siab. Tom qab qhia txog ntawm cov tshuaj, kho muaj pes tsawg leeg pib ua yeeb yam hauv 2 teev. Qhov siab tshaj plaws tau tiav tom qab 12 teev. Kev kho ua kom ntev li ib hnub.

Leej twg raug tsa

Ua ntej pib kev kho mob, cov lus qhia rau kev siv thiab cov lus piav qhia ntawm "Rosinsulin S" yuav tsum tau kawm kom paub meej tias cov tshuaj tau sau tseg rau yam twg thiab yuav siv nws li cas. Nco ntsoov sab laj tus kws kho mob, nws yog qhov tsim nyog los txiav txim siab qhov tsim nyog ntawm nws txoj kev siv. Nws yog txwv tsis pub ywj siab rau yuav thiab siv tshuaj, vim tias muaj qhov tshwm sim tsis zoo. Cov kws kho mob pom zoo kom noj cov tshuaj nyob rau hauv cov kev kuaj pom xws li:

ntshav qab zib hom 1 thiab hom 2
mob ntshav qab zib thaum cev xeeb tub
nyob rau lub sijhawm tom qab lossis sijhawm ua haujlwm tas.

Tsis tas li ntawd, qhov kev hais daws no tau raug sau tseg thaum tsis muaj txiaj ntsig los ntawm kev noj lwm yam tshuaj hypoglycemic, zoo li ntxiv rau kev kho mob tseem ceeb.

Cov tshuaj noj

Raws li cov lus qhia rau kev siv, "Rosinsulin C" yog hais txog kev npaj rau kev tswj hwm hauv qab daim tawv nqaij. Cov koob tshuaj yog xaiv rau hauv kev txiav txim siab kuaj mob thiab theem ntawm cov piam thaj hauv cov ntshav. Ua ntej pib kev kho mob, koj yuav tsum tau mus ntsib kws kho mob los laij ib txoj kev kho mob. Qhov nruab nrab cov tshuaj pom zoo ntau nyob ntawm daim ntawv ntawm cov tshuaj. 1 ml ntawm kev tshem tawm muaj txog li 100 IU.

Raws li cov lus qhia rau kev siv, Rosinsulin M raug siv tshuaj hauv 0.5-1 IU ib kg ntawm tus neeg mob lub cev. Tom qab, cov yam ntxwv ntawm cov muaj pes tsawg leeg cov ntshav thiab ntshav qabzib tau kawm, thiab txoj kev xaiv kev noj haus tau raug xaiv.

Raws li tau hais hauv cov lus qhia rau kev siv, "Rosinsulin R" yog tshaj tawm ntawm 40 ib hnub. Cov txheej txheem kev tswj hwm yog nyob ntawm kev suav cov ntshav ua ntej thiab tom qab noj mov. Muab tshuaj rau noj:

subcutaneously
intramuscularly
tso leeg ntshav.

Feem ntau cov feem ntau, Rosinsulin R yog muab tshuaj subcutaneously. Yog tias qhov kuaj ntshav qab zib tau kuaj pom lossis phais tau qhia, cov tshuaj tau muab tshuaj intramuscularly lossis intravenously. Nrog rau cov tshuaj monotherapy, cov tshuaj no siv 3 zaug hauv ib hnub. Hauv qee kis, qhov ntau zaus ntawm kev tswj hwm ntawm cov tshuaj yog txog li rau lub sijhawm hauv ib hnub. Txhawm rau kom tsis txhob lipodystrophy thiab atrophy, qhov chaw txhaj tshuaj yuav tsum tau hloov txhua zaus.

Raws li cov lus qhia rau kev siv, Rosinsulin S yog tus kws kho mob muab tshuaj rau kom tsis pub ntau tshaj 24 IU. Cov tshuaj yog muab tshuaj 1-2 zaug ib hnub subcutaneously. Cov khw tsim kev pom zoo hloov cov chaw txhaj tshuaj txhua lub sijhawm. Cov tshuaj no tau noj 30 feeb ua ntej noj tshais. Qee qhov xwm txheej, tus neeg mob raug samfwm kom txhaj tshuaj, thiab tso tshuaj rau thawj zaug yog txwv.

Ua ntej siv cov tshuaj, koj yuav tsum tau sov nws rau chav kub.Koj kuj yuav tsum tau co lub raj mis kom tau txais kev faib ntau dua ntawm cov tshuaj. Qhov chaw tswj hwm yog txiav txim los ntawm kws kho mob. Qhov no feem ntau yog lub plab phab ntsa, ncej puab, xub pwg lossis pob tw.

Hauv cov xwm txheej txheem, raws li cov lus qhia rau kev siv, Rosinsulin N raug tshuaj rau 8-24 IU ib hnub ib zaug. Yog hais tias tus neeg mob muaj lub siab rhiab rau insulin, tom qab ntawd cov tshuaj tau sau hauv qhov tsawg kawg nkaus, thiab nrog txo tus mob siab, qhov koob tshuaj yog ntau dua 24 IU ib hnub.

Cev xeeb tub

Raws li tau hais hauv cov lus qhia rau kev siv, Rosinsulin C thaum cev xeeb tub thiab kev pub niam mis tuaj yeem siv rau kev kho mob, vim tias cov khoom xyaw nquag tsis nkag rau hauv lub plab.

Ua ntej npaj kev xeeb tub, nws raug nquahu kom kuaj ntshav ntawm cov ntshav qab zib. Yog tias muaj cov cim qhia tau ntau ntxiv, tus kws kho mob tau sau ntawv rau Rosinsulin. Thaum pub niam mis, nws muaj cai siv cov tshuaj no, vim tias tsis muaj ntaub ntawv hais txog nws nkag mus rau hauv niam mis.

Siv rau lub sijhawm menyuam yaus thiab hnub nyoog laus

"Rosinsulin" tuaj yeem siv los kho menyuam yaus, txawm li cas los xij, koj yuav tsum kho cov tshuaj ntau npaum li cas. Nws tseem yog qhov tseem ceeb los saib xyuas kev noj qab haus huv thiab lus pov thawj.

Ib hom tshuaj tau tso cai rau kho cov neeg laus, tab sis nws yuav tsum siv kom zoo, vim tias lawv muaj kev pheej hmoo siab los ntawm kev mob ntshav qab zib thiab exacerbation ntawm lwm cov kab mob concomitant.

Cov Yuav Tsum Muaj

Ua ntej siv cov tshuaj, nws yog ib qho tsim nyog yuav tsum kawm cov lus qhia rau kev siv "Rosinsulin C". Tus nqi ntawm cov tshuaj thaj tsam 926 rubles. Nws yog txwv tsis pub siv nws yam tsis tau sab laj nrog kws kho mob. Qhov no yog vim tias ib qho ua rau hauv qabzib poob rau qhov tseem ceeb.

Txhawm rau tiv thaiv kev txhim kho ntawm cov teeb meem, koj yuav tsum ua kom meej meej cov lus qhia, thiab tseem coj contraindications. Nws yog nruj me ntsis txwv tsis pub siv cov cuab yeej no thaum muaj qhov ntsuas siab nyob rau hauv cov tshuaj, zoo li ua rau ntshav qab zib tsawg.

Sab sij huam

Kev siv tsis zoo ntawm "Rosinsulin" entails cov kev phiv tsis zoo rau lub cev. Txhawm rau ua qhov no, nws raug nquahu kom koj ua raws li cov kws kho mob sau tseg kom meej meej, tsis txhob hloov pauv rau kev kho koj tus kheej Cov kev mob tshwm sim muaj xws li:

lub siab ua ntxhov,
daim tawv nqaij ua pob,
pallor
mob taub hau
o thiab hlawv ntawm qhov chaw txhaj tshuaj,
txog hlab ntshav puv.

Yog tias muaj qhov tshwm sim tsis zoo, koj yuav tsum sab laj tus kws kho mob txhawm rau kho qhov kev kho mob.

Yeeb tshuaj sib cuam tshuam

Cov tshuaj "Rosinsulin" yog qhov tsim nyog rau kev kho mob nyuaj nrog rau lwm cov tshuaj. Ua ntej pib txoj kev kho ua ke, koj yuav tsum sab laj nrog tus kws kho mob. Nws yuav ua lub sijhawm teem sijhawm, nrog rau suav kev xam qhov ntau npaum li cas, suav rau hauv kev sib cuam tshuam ntawm cov khoom siv nquag.

Nrog kev ceev faj, koj yuav tsum noj "Rosinsulin" nrog rau lwm txoj hauv kev los ua kom cov ntshav qabzib ntau ntau. Kev ua kom tsis muaj zog ntawm qhov xav tau yog pom nrog kev tswj hwm tib lub sij hawm nrog diuretics, tshuaj ntxiv, tshuaj tua kab mob.

Analogues ntawm cov tshuaj

Ua ntej yuav cov tshuaj, koj yuav tsum kawm cov lus qhia rau kev siv thiab tshuaj xyuas "Rosinsulin" Tus nqi ntawm cov tshuaj muaj li 100 rubles. Nws muaj ib tug xov tooj ntawm cov tshuaj zoo sib xws uas tau sau tseg yog muaj contraindications. Ntawm cov analogues, nws yog ib qho tsim nyog los ua kom pom xws li:

Cov tshuaj "Novomix" yog insulin uas muaj ob-ntu. Nws yog qhov txawv los ntawm nws txoj kev nrawm thiab ua haujlwm zoo. Nws tsis raug sau tseg rau cov menyuam yaus hnub nyoog qis dua 6 xyoo. Feem ntau ntawm qhov chaw txhaj tshuaj, kev fab tshuaj muaj tshwm sim.

Cov tshuaj "Insuman" 3 hom kev txiav txim. Nws yog siv rau kev kho mob menyuam yaus thiab cov laus. Qhov cuab yeej no tsis tshua muaj kev cuam tshuam cov kev mob tshwm sim.

Cov tshuaj "Protafan" tau muab tshuaj tsuas yog subcutaneously, nws yog siv los kho cov neeg mob ntawm txhua lub hnub nyoog. Nws tuaj yeem siv los ntawm cov poj niam cev xeeb tub thiab thaum lactation.

Cov kws kho mob cov lus ntuas

Cov kws kho mob hais tias thaum lub sijhawm nws yug menyuam thiab tom qab yug menyuam, xav tau cov tshuaj insulin tsawg dua. Hauv qhov no, tus pojniam yuav tsum nyob hauv kev saib xyuas ntawm cov kws kho mob. Cov kws kho mob tau hais tias cov tshuaj no tau tshwm sim zoo nrog kev siv tas li.

Lawv tau sib cav hais tias cov tshuaj no tsis muaj qhov sib txuam thiab muaj kev phiv yog tias siv raug.

Kev Ntsuam Xyuas Rau Neeg Mob

Kev txheeb xyuas cov neeg mob ntshav qab zib nrog kev paub txog cov tshuaj no feem ntau zoo. Lawv sau tseg yooj yim ntawm kev siv, muaj peev xwm los ua ke ntawm ntau hom tshuaj insulin. Txawm li cas los xij, muaj cov tib neeg rau nws uas yog qhov tsis tsim nyog kiag li.

Coob tus hais tias qhov no yog cov khoom lag luam hauv tsev, tab sis hauv kev ua tau zoo nws yog tiag tsis qis tshaj rau ib tus neeg txawv teb chaws. Tab sis qee kis, nws provokes hypoglycemia heev.

Yuav siv li cas: noj ntau thiab hom tshuaj kho

Qhov koob tshuaj thiab txoj hauv kev ntawm kev tswj hwm tshuaj yog txiav txim siab ntawm txhua tus neeg nyob rau hauv lub hauv paus ntawm cov piam thaj hauv cov ntshav ua ntej noj mov thiab 1-2 teev tom qab noj mov, thiab tseem nyob ntawm qhov ntsuas ntawm glucosuria thiab cov yam ntxwv ntawm chav kawm ntawm tus kabmob.

Cov tshuaj yog muab s / c, hauv / m, hauv / hauv, 15-30 feeb ua ntej noj mov. Txoj kev sib txawv ntawm kev tswj hwm yog sc. Nrog cov ketoacidosis uas mob ntshav qab zib, mob ntshav qab zib tsis xeev, thaum phais mob kev cuam tshuam - hauv / thiab / m.

Nrog kev kho mob monotherapy, qhov ntau zaus ntawm kev tswj hwm feem ntau yog 3 zaug hauv ib hnub (yog tias tsim nyog, txog li 5-6 zaug hauv ib hnub), qhov chaw txhaj tshuaj tau hloov pauv txhua lub sijhawm kom tsis txhob muaj kev txhim kho ntawm lipodystrophy (atrophy lossis hypertrophy ntawm subcutaneous rog).

Qhov nruab nrab txhua hnub koob tshuaj yog 30-40 PIECES, hauv cov menyuam yaus - 8 PIECES, tom qab ntawd qhov nruab nrab txhua hnub - 0.5-1 PIECES / kg lossis 30-40 PIECES 1-3 zaug hauv ib hnub, yog tias tsim nyog - 5-6 zaug ib hnub. Hauv kev noj tshuaj ib hnub dhau ntawm 0.6 U / kg, tshuaj insulin yuav tsum tau txhaj rau 2 lossis ntau dua kev txhaj tshuaj hauv ntau qhov chaw ntawm lub cev.

Nws yog qhov ua tau los ua ke nrog insulins ntev-coj.

Cov kua tshuaj insulin yog sau los ntawm lub vial los ntawm kev hno nrog rab koob syringe koob lub roj hmab nres uas tau so tom qab hle lub hau txhuas nrog ethanol.

Pharmacological kev txiav txim

Luv luv ua yeeb yam insulin npaj. Sib cuam tshuam nrog ib qhov tshwj xeeb receptor rau ntawm sab nraud ntawm lub hlwb, tsim cov txheej txheem insulin. Los ntawm nce cov synthesis ntawm cAMP (hauv cov roj ntsha thiab lub siab hlwb) lossis nkag ncaj qha rau hauv lub cell (leeg), insulin receptor complex stimulates intracellular processes, suav nrog synthesis ntawm tus lej ntawm cov enzym tseem ceeb (hexokinase, pyruvate kinase, glycogen synthase, thiab lwm yam). Kev txo qis hauv cov concentration ntawm cov piam thaj hauv cov ntshav yog vim muaj kev nce ntxiv hauv nws txoj kev thauj mus los, kev nqus thiab kev pov tseg ntawm cov nqaij mos, qhov kev txhawb nqa ntawm lipogenesis, glycogenogenesis, synthesis protein, txo tus nqi ntawm cov piam thaj los ntawm lub siab (txo qis ntawm kev puas tsuaj ntawm glycogen), thiab lwm yam.

Tom qab sc txhaj tshuaj, cov nyhuv tshwm sim li ntawm 20-30 feeb, nce mus txog qhov siab tshaj plaws tom qab 1-3 teev thiab kav ntev, nyob ntawm qhov koob tshuaj, 5-8 teev. Lub sijhawm ntawm cov tshuaj nyob ntawm qhov ntau npaum li cas, txoj kev, qhov chaw tswj hwm thiab muaj tus yam ntxwv tseem ceeb ntawm tus kheej Cov.

Sab sij huam

Kev tsis haum tshuaj (urticaria, angioedema - ua npaws, ua tsis taus pa, ua pa tsis txaus),

hypoglycemia (pallor ntawm daim tawv nqaij, nce tawm hws, tawm hws, palpitations, tshee tshee, tshaib plab, ntxhov siab, ntxhov siab, mob plab hauv lub qhov ncauj, mob taub hau, tsaug zog, pw tsaug zog, ntshai, poob siab, chim siab, coj tus cwj pwm txawv, tsis muaj zog, hais lus thiab hais lus tsis meej thiab qhov pom kev), hypoglycemic coma,

hyperglycemia thiab ntshav qab zib acidosis (thaum qis koob, hla kev txhaj tshuaj, noj zaub mov tsis zoo, tiv thaiv keeb kwm ntawm kub ib ce thiab kis kab mob): tsaug zog, nqhis dej, tsis qab los noj mov, ntsej muag tawm ntsej muag),

hnov tsis nco qab (txog rau kev txhim kho ntawm precomatose thiab coma),

pom kev tsis pom kev tsis zoo (feem ntau thaum pib kho mob),

txhaj tshuaj tiv thaiv kab mob hla nrog tib neeg cov tshuaj insulin, nce ntxiv ntawm lub titer ntawm cov tshuaj tiv thaiv insulin, tom qab los ntawm kev nce glycemia,

hyperemia, khaus thiab lipodystrophy (mob atrophy lossis hypertrophy ntawm subcutaneous rog) ntawm qhov chaw txhaj tshuaj.

Thaum pib ntawm kev kho mob - o thiab tsis hnov mob zoo (yog ib ntus thiab ploj nrog kev kho txuas ntxiv).

Kev sib txuam

Cov tshuaj tsis sib haum nrog kev daws teeb meem ntawm lwm cov tshuaj.

Cov nyhuv hypoglycemic yog txhim kho los ntawm sulfonamides (suav nrog qhov ncauj tshuaj hypoglycemic, sulfonamides), MAO inhibitors (suav nrog furazolidone, procarbazine, selegiline), carbonic anhydrase inhibitors, ACE inhibitors, NSAIDs (suav nrog salicylates), anabolic (suav nrog stanozolol, oxandrolone, methanedienone), androgens, bromocriptine, tetracyclines, clofibrate, ketoconazole, mebendazole, theophylline, cyclophosphamide, phenfluramine, Li + kev npaj, pyridoxine, quinidine, quinine, chloroneinine.

Hypoglycemic los ntawm lus glucagon, kev loj hlob lawm, corticosteroids, qhov ncauj contraceptives, estrogens, thiazide thiab "voj" diuretics, BCCI, thyroid hormones, heparin, sulfinpyrazone, sympathomimetics, danazol, tricyclics, clonidine, BCCI, diazoxide, morphine, tshuaj maj, nicotine, phenytoin , epinephrine, H1-histamine receptor blockers.

Beta-blockers, reserpine, octreotide, pentamidine tuaj yeem txhim kho ob qho tib si thiab ua kom cov nyhuv tsis muaj zog hypoglycemic ntawm insulin.

Rinsulin P - cov lus qhia rau kev siv

Rinsulin P yog suav tias yog tshuaj lom neeg rau tib neeg. Nws tau txais vim siv cov thev naus laus zis siv DNA thev naus laus zis. Soluble insulin yog xim ua kua, ntshiab kua. Cov tshuaj yog npaj rau kev txhaj tshuaj rau cov leeg ntshav, intramuscularly thiab subcutaneously. Tus neeg sawv cev hypoglycemic yog tsom rau cov neeg uas cov ntshav qab zib kom poob mus rau theem tseem ceeb.

Kev Sib Sau thiab daim ntawv ntawm kev tso tawm

Kev daws rau kev txhaj tshuaj

Tib neeg cov tshuaj insulin

Excipients muaj nyob hauv qhov npaj: glycerol (glycerin) - 16 mg, metacresol - 3 mg, dej d / i - txog 1 ml. Qhov ntim ntawm lub raj mis yog 10 ml. Muab tso rau hauv lub thawv ntawv thawv, blister sawb ntim tau 5 cartridges. Ib lub iav vial tau muab ntim rau hauv cov chaw pov tseg ntau cov koob txhaj tshuaj, tsim rau kev hno rov qab, tuav 3 ml.

Pharmacodynamics thiab pharmacokinetics

Lub sijhawm ntawm cov tshuaj yog txiav txim siab los ntawm tus nqi ntawm kev nqus ntawm insulin hauv cov ntshav thiab nyob ntawm plaub yam:

los ntawm cov koob tshuaj ntawm cov tshuaj (tus nqi ntawm cov tshuaj insulin txhaj),
los ntawm kev mloog ntawm cov kua dej hauv cov tshuaj,
qhov chaw txhaj tshuaj (ncej, pob tw, plab),
txoj kev ntawm kev tswj hwm (intramuscularly, intravenously, subcutaneously).

Qhov nruab nrab, tom qab kev tswj hwm, insulin pib ua hauv 20-30 feeb, qhov ua tiav siab tshaj plaws tau tiav ntawm 1-3 teev. Cov nyhuv ntawm cov tshuaj, nyob ntawm lub koob tshuaj, kav ib tug nruab nrab ntawm 8 teev. Qhov tsis zoo ntawm cov tshuaj yog tias cov tshuaj daws tau faib tsis xwm yeem thoob plaws cov leeg nqaij. Insulin molecules puas tsuaj los ntawm insulinase hauv daim siab thiab lub raum. Rinsulin yog tawm, raws li txoj cai, los ntawm ob lub raum.

Tsuas tshuaj thiab tswj hwm

Qhov koob tshuaj thiab txoj hauv kev ntawm kev tswj hwm tshuaj yuav tsum txiav txim los ntawm tus kws kho mob.

Subcutaneous kev tswj hwm yog txoj kev siv ntau tshaj. Tso ncaj thiab intramuscularly, cov tshuaj tau raug tswj hwm hauv kev mob hnyav, piv txwv li, nrog kev phais tom ntej lossis mob ntshav qab zib tsis nco qab.

Cov tshuaj insulin muab rau noj 20-30 feeb ua ntej ib pluas noj uas muaj cov carbohydrates. Kev daws yuav tsum nyob ntawm chav sov.

Cov tshuaj yog txhaj rau hauv pem hauv ntej lub plab phab ntsa, qhov chaw siab tshaj plaws tau ua tiav. Koj tuaj yeem nkaug rau tus ncej, pob tw, lossis deltoid thaj tsam ntawm lub xwb pwg. Thaum tswj cov insulin subcutaneously, nws yog qhov tseem ceeb kom tsis txhob ua mob rau cov hlab ntshav. Koj tuaj yeem tsis prick nyob hauv tib qho chaw ob peb zaug ua ke, muaj kev pheej hmoo ntawm lipodystrophy.

Thaum muaj kev kho mob monotherapy, cov tshuaj yuav tsum qhia rau hauv lub cev 3 zaug hauv ib hnub (rau qee tus neeg mob - 5-6 zaug). Ua raws li cov concentration ntawm cov piam thaj hauv cov ntshav, cov tshuaj txhua hnub yog los ntawm 0.3 mus rau 1 IU / kg ntawm lub cev hnyav.

Kev siv daim cartridge tsis tuaj yeem lees paub yog tias kev daws teeb meem tau khov lossis ib qho nag lossis daus tau tshwm sim hauv nws. Lub taub hau thiab rab koob yuav siv tau ib zaug.

Kev siv cov koob txhaj tshuaj yuav tsum tshwm sim nruj me ntsis raws li cov khw muag cov lus qhia. Ua ntej nqa tawm cov txheej txheem, koj yuav tsum tshem ib tus xaum xoos xaum tawm hauv lub tub yees thiab tos kom txog thaum cov tshuaj insulin tau mus txog rau qhov chaw sov, tom qab ntawd siv rab koob koj tuaj yeem nkag mus siv tshuaj. Tom qab txhaj koob, rab koob yuav tsum tau unscrewed nrog lub hau thiab tam sim ntawd tshem tawm kom muaj kev nyab xeeb.

Cov Lus Cim Rinsulin P

Muaj cov naj npawb txaus ntawm cov yeeb yaj kiab ntawm cov tshuaj, ob qho tib si Lavxias thiab txawv teb chaws.

Actrapid NM (Novo Nordisk, Denmark),
Biosulin (Pharmstandard-UfaVITA, Russia),
Gensulin R ("Bioton S. A.", Poland),
Vosulim-R (Wokhard Ltd, Is Nrias teb),
Insuran R (Lub Koom Haum ntawm Bioorganic Chemistry RAS, Russia),
Rosinsulin R (Honey Synthesis, Russia),
Monoinsulin CR (Belmedpreparaty, Belarus),
Humodar R 100 Hav dej (Indar, Ukraine),
Humulin Tsis Txaus (Lilly Fabkis, Fabkis).

Rinsulin R yog cov tshuaj uas tsim los ntawm GEROPHARM-Bio. Cov nqi sib piv rau cov tshuaj hauv cov khw muag tshuaj hauv Moscow:

Cov nquag ua haujlwm ntawm cov pawg P thiab C

Rosinsulin P raug txiav txim siab luv-acting soluble insulinCov. Nws yooj yim cuam tshuam nrog cov tshwj xeeb receptor rau ntawm daim nyias nyias ntawm cov hlwb, ua rau cov insulin receptor complex. Tawm tsam keeb kwm ntawm kev kho, cAMP hluavtaws hauv lub siab thiab cov roj ua haujlwm nce. Lub zog ua ke ntawm cov tshuaj kuj nkag mus rau cov leeg hlwb, txhawb kev ua si ntawm hexokinase thiab lwm cov txheej txheem dej num.

Vim tias muaj cov protein ua ke ua ke ntau zog, cov concentration ntawm cov piam thaj hauv cov ntshav thiab tawg ntawm glycogen yog txo qis. Tom qab txhaj tshuaj, raug saib xyuas rau 30 feeb. Lub sijhawm ua haujlwm ntawm ib koob tau txog 8 teev. Tus nqi ntawm qhov ntsuas no nyob ntawm qhov ntau npaum li cas, txoj kev thiab thaj chaw tswj hwm.

Rosinsulin C yog nthuav tawm li insulin-isophan nrog qhov txiaj ntsig zoo nruab nrab. Cov tshuaj txo cov tshuaj nyob rau hauv cov ntshav ntawm cov ntshav, ua rau nws nqus tau los ntawm cov ntaub so ntswg, txhim kho lipogenesis. Qhov no txo cov nqi ntawm cov piam thaj los ntawm lub siab.

Tom qab txhaj tshuaj, qhov muaj pes tsawg leeg pib ua tom qab 2 teev. Kev ua hauj lwm siab tshaj plaws tau tiav tom qab 12 teev. Kev kho mob nyhuv ntev txog li ib hnub. Tus nqi ntawm qhov ntsuas no cuam tshuam ncaj qha los ntawm cov koob tshuaj thiab cov qauv ntawm cov tshuaj noj.

Kev taw qhia thiab contraindications

Cov lus qhia rau kev teem caij siv cov tshuaj no muaj ntau yam.

Cov no suav nrog:

hom 1 thiab hom 2 mob ntshav qab zib mellitus (hauv qhov tsis muaj tshwm sim los ntawm kev kho mob nrog lub qhov ncauj hypoglycemic los yog tsis muaj txiaj ntsig tsis txaus),
mob ntshav qab zib uas tau tshwm sim thaum lub sijhawm xeeb tub,
ketoacidosis
ketoacidotic coma,
npaj ntev ua yeeb yam kho insulin,
cov kab mob sib kis hauv cov ntshav qab zib.

Cov nta no xav tau kev kho mob nrog cov tshuaj insulin, tab sis lawv qhov tsis tau txhais tau tias kev kho mob ntawd yuav tsum pib tam sim ntawd. Ua ntej tshaj, nco ntsoov tias tsis muaj kev sib txuam sib kis. Vim tias ntawm lawv, koj feem ntau yuav tsum tso tseg kev siv Rosinsulin.

Lub ntsiab contraindications hu ua:

Kev tshawb pom ntawm cov yam ntxwv no yuav tsum tau xaiv lwm txoj kev, txij li siv Rosinsulin tuaj yeem ua rau tsis zoo.

Cov lus qhia rau kev siv

Yuav kom tau txais txiaj ntsig, txhua yam tshuaj yuav tsum tau siv raws li cov lus qhia. Qhov ua kom paub daws teeb rau Rosinsulin tsis pab ntau, vim txhua tus neeg mob yuav muaj cov yam ntxwv uas yuav tsum tau kho ntawm lub sijhawm thiab koob tshuaj. Yog li no, cov lus qhia meej los ntawm kws kho mob yog xav tau.

Cov tshuaj no yog siv los ua qhov koob txhaj, uas tau muab tshuaj subcutaneously. Qee lub sijhawm tso tshuaj lossis tso ntshav mus tso cai, tab sis nws yog nqa los ntawm tus kws tshaj lij xwb.

Cov zaus ntawm kev txhaj tshuaj thiab cov koob tshuaj ntawm cov tshuaj tau suav ib tus zuj zus raws li cov yam ntxwv ntawm cov duab hauv chaw kuaj mob.Yog tias tsis muaj cov yam ntxwv ntxiv, 0.5-1 IU / kg ntawm qhov hnyav yog siv rau ib hnub. Nyob rau yav tom ntej, kev hloov pauv hauv cov ntshav hauv lub ntsej muag tau kawm thiab cov koob tshuaj tau hloov kho yog tias tsim nyog.

Qee zaum Rosinsulin qee lub sijhawm siv nrog kev sib tw ntev ntawm cov kua dej. Hauv qhov no, cov koob tshuaj yuav tsum tau hloov pauv.

Kev txhaj tshuaj yuav tsum tau txhaj ua ntej noj mov (rau 20-30 feeb). Hauv tsev, cov tshuaj yog muab tshuaj subcutaneously hauv tus ncej puab, xub pwg, lossis sab hauv plab phab ntsa. Yog tias cov koob tshuaj uas tus kws kho mob tau tshaj li 0.6 IU / kg, nws yuav tsum tau muab faib ua ntau ntu. Qhov chaw txhaj tshuaj yuav tsum tau hloov chaw kom tsis muaj teeb meem ntawm daim tawv nqaij.

Cov lus qhia ua yeeb yaj kiab rau kev qhia txog cov tshuaj insulin nrog cov xaum xaum:

Cov Neeg Mob Tshwj Xeeb thiab Cov Lus Qhia

Qee tus neeg mob xav tau kev tiv thaiv tshwj xeeb. Qhov no yog vim muaj cov yam ntxwv ntawm lawv lub cev, vim qhov ntawd Rosinsulin tuaj yeem cuam tshuam lawv nyob rau hauv kev coj txawv txawv.

Cov neeg mob no suav nrog:

Cov menyuam. Hauv thaum yau, kev kho mob insulin tsis txwv, tab sis yuav tsum tau saib xyuas ntau dua los ntawm kws kho mob. Cov koob tshuaj ntawm cov tshuaj yog teem rau lawv me ntsis qis dua li cov neeg laus ntshav qab zib.
Cev xeeb tub Cov tshuaj no tsis ua mob rau cov poj niam thaum ua menyuam, yog li nws tau siv los nruab nrab rau cov tsos mob ntshav qab zib. Tab sis thaum cev xeeb tub, qhov xav tau ntawm insulin tuaj yeem sib txawv raws li lub sijhawm, yog li koj yuav tsum tau saib xyuas cov kua nplaum nyeem thiab kho qhov seem ntawm cov tshuaj.
Saib xyuas niam cov txiv. Lawv kuj tsis raug txwv los ntawm kev kho insulin. Cov tshuaj ua ke los ntawm cov tshuaj tuaj yeem hla mus rau niam mis, tab sis lawv tsis muaj qhov tsis zoo rau tus menyuam. Cov tshuaj insulin yog cov protein ua kom cov menyuam lub cev sib kis tau yooj yim. Tab sis thaum siv Rosinsulin, cov poj niam uas xyaum noj cov zaub mov ntuj yuav tsum ua raws li kev noj haus.
Qub neeg. Hais txog qhov lawv xav tau ceev faj yog vim muaj kev hloov pauv ntawm lub hnub nyoog. Cov kev hloov no tuaj yeem cuam tshuam txog ntau yam kabmob, nrog rau daim siab thiab lub raum. Nyob rau hauv qhov kev ua txhaum ntawm kev ua haujlwm ntawm cov plab hnyuv siab raum, insulin excretion qeeb qeeb. Yog li, cov neeg mob hnub nyoog tshaj 65 xyoos tau sau tseg kom txo qis ntawm cov tshuaj.

Koj kuj yuav tsum tau ua tib zoo kho kev kho mob ntawm cov neeg uas muaj ntau lub pathologies. Qee ntawm lawv cuam tshuam qhov kev txiav txim ntawm Rosinsulin.

Ntawm lawv yog hu ua:

Kev tsis sib haum xeeb hauv kev ua haujlwm ntawm lub raum. Vim hais tias ntawm lawv, qhov kev nthuav tawm ntawm cov tshuaj nquag ua rau qeeb, uas tuaj yeem ua rau lawv cov tsub zuj zuj thiab tshwm sim ntawm cov ntshav qog ntshav qab zib. Yog li, cov neeg zoo li no yuav tsum tau ua tib zoo suav ntsuas cov tshuaj noj.
Pathology ntawm lub siab. Nyob rau hauv kev cuam tshuam ntawm insulin, daim siab ua rau qis qis ntawm cov piam thaj. Yog tias muaj teeb meem hauv nws txoj haujlwm, cov piam thaj tuaj yeem tsim tawm ntau dua, uas ua rau nws lub cev tsis txaus. Qhov no txhais tau hais tias yog muaj kev ua txhaum cai nyob rau hauv cov kev ua haujlwm ntawm lub cev no, cov koob tshuaj yuav tsum raug txo kom tsawg.

Cov tshuaj Rosinsulin ib leeg tsis ua rau muaj kev hloov pauv hauv kev muaj peev xwm mloog zoo thiab tsis qeeb tus tshuaj tiv thaiv. Lawv tuaj yeem ua rau npau taws los ntawm kev mob ntshav qab zib los ntawm qhov siv tsis tau ntawm tus neeg sawv cev no. Hauv qhov no, kev tsav tsheb thiab cov haujlwm phom sij thaum siv cov tshuaj no yog qhov tsis xav tau.

Kev Kho Mob

Cov tshuaj ntawm pawg C yog tau txais 1-2 zaug hauv ib hnub. Cov chaw tsim khoom lag luam tawm tswv yim txhua zaus tom ntej kom hloov thaj chaw txhaj tshuaj. Cov tshuaj no tau noj 30 feeb ua ntej noj tshais. Tsis tshua muaj, txhaj tshuaj intramuscular nrog Rosinsulin C raug kho rau tus neeg mob. Kev tswj hwm ntshav yog txwv.

Dosage yog xaiv ib tus zuj zus. Nws nyob ntawm cov piam thaj hauv cov zis thiab ntshav, cov yam ntxwv ntawm chav kawm ntawm tus kabmob. Hauv cov xwm txheej txheem, nws txaus los nkag 8-24 IU ib hnub ib zaug. Yog hais tias tus neeg mob muaj lub siab rhiab rau insulin, cov tshuaj tau sau tseg hauv qhov tsawg kawg nkaus, thiab nrog txo qhov mob siab - hauv ib koob ntau dua 24 IU ib hnub. Yog tias nyob rau yav tav su cov tshuaj ntau dua 0.6, ob qhov kev txhaj tshuaj tau raug tswj hwm nyob hauv ntau qhov chaw. Cov neeg mob uas tau txais ntau dua 100 IU ib hnub yog mus pw hauv tsev kho mob nrog kev hloov pauv tshuaj insulin.

Kev kho mob nrog Rosinsulin P yog tus kheej. Tsuas tshuaj thiab cov tswv yim txheej txheem nyob ntawm cov ntshav suav ua ntej thiab tom qab noj mov, qhov qib ntawm glycosuria. Cov hau kev kev tswj hwm:

Ntau zaus Rosinsulin P yog muab tshuaj subcutaneously. Yog tias mob ntshav qab zib tsis nco qab tau paub tseeb lossis phais mob tau qhia, qhov muaj pes tsawg leeg yog tswj hwm intramuscularly lossis leeg ntshav. Nrog rau cov tshuaj monotherapy, cov tshuaj no tau thov peb zaug ib hnub. Tsis tshua muaj qee zaus, zaus ntawm kev tswj hwm ncav cuag 6 zaug hauv ib hnub. Txhawm rau kom tsis txhob mob atrophy, lipodystrophy, qhov chaw txhaj tshuaj hloov txhua zaus tom qab.

Qhov muab cov tshuaj txhua hnub rau qhov nruab nrab yuav tsum tsis pub ntau tshaj 40 units. Cov menyuam raug xaj nyob rau ntawm 8 koob. Yog tias ntau tshaj 0.6 units hauv 1 kg ntawm qhov hnyav uas tau hais tawm, cov tshuaj insulin raug tswj hwm ob zaug thiab hauv ntau qhov chaw ntawm lub cev. Yog tias tsim nyog, Rosinsulin C sib xyaw ua ke nrog insulin ntev ntev.

Kev phiv tshuaj

Cov tshuaj ntawm ib pab pawg hauv cov lus nug tuaj yeem ua rau ua xua nyob rau hauv daim ntawv ntawm urticaria. Dyspnea zoo li tsawg zaus, siab poob qis. Lwm cov tsos mob tsis zoo ntawm Rosinsulin P thiab C:

insomnia
mob taub hau
tsis qab los noj mov
nco qab teeb meem
nce titer ntawm cov tshuaj tiv thaiv insulin.

Nyob rau theem pib ntawm kev kho, cov neeg mob feem ntau yws ntawm edema thiab tsis hnov lus zoo. Cov tsos mob ploj sai li sai tau. Kev saib xyuas tshwj xeeb yog them rau qhov xwm txheej ntawm lub raj mis. Ua ntej tswj hwm, txoj kev daws teeb meem raug kuaj xyuas rau pob tshab. Yog tias muaj lub cev txawv teb chaws hauv cov kua dej, Rosinsulin tsis siv.

Qhov ntau npaum ntawm cov tshuaj muaj kho rau kev kis mob, cov thyroid tsis ua hauj lwm, Addison syndrome. Hypoglycemia feem ntau loj hlob ua ib qho tsos mob ntawm kev haus ib ce tshaj. Cov tsos mob zoo sib xws yog pom thaum hloov Rosinsulin C thiab P nrog lwm tus neeg sawv cev. Lwm cov tsos mob ntawm overdose:

ntuav
zawv plab
txo qis hauv kev ua haujlwm ntawm lub zog.

Yog tias lub chaw kho mob saum toj saud tshwm sim, nws raug nquahu kom ceeb toom rau tus kws kho mob uas koom nrog. Ntau zaus cov neeg mob tau qhia kom mus rau tsev kho mob. Cov txheej txheem hauv qab no yog xaiv tom qab kev soj ntsuam tag nrho ntawm tus neeg mob.

Yog tias tus neeg mob muaj kab mob siab thiab lub raum, qhov xav tau tshuaj tsawg. Cov kua nplaum ntawm lub ntsej muag tuaj yeem pauv thaum tus neeg mob hloov mus los ntawm tsiaj mus rau tib neeg los ntawm insulin. Xws li hloov mus yuav tsum kho kom raug. Nws yog nqa hauv kev saib xyuas ntawm cov kws kho mob.

Cov lus qhia kho mob

Tus mob ntshav qab zib nres nres qhov tsis hnov mob ntshav qab zib tsawg los ntawm kev noj qab zib. Thaum tus mob hnyav zuj zus, kev kho kho kom haum. Yog tias tus neeg mob lub cev xeeb tub, Cov hauv qab no yog coj mus rau hauv tus account:

Hauv 1 hlis twg, cov tshuaj tau txo kom tsawg.
Hauv kev txiav thib 2 thiab 3, kev xav tau Rosinsulin ntau ntxiv.

Thaum lub sijhawm thiab tom qab yug menyuam, xav tau cov tshuaj tsawg dua. Nrog kev pub mis, tus poj niam nyob hauv kev saib xyuas txhua hnub ntawm cov kws kho mob.

Los ntawm cov kws tshuaj pom, Rosinsulin P thiab C tsis sib xws nrog kev daws ntawm lwm yam tshuaj. Hypoglycemic nyhuv yog txhim kho los ntawm kev nqus ntawm sulfonamides, monoamine oxidase inhibitors thiab angiotensin-hloov pauv enzyme. Cov txiaj ntsig kho tau tsis muaj zog los ntawm glucagon, glucocorticoids, qhov ncauj tawm tsam, Danazole. Beta-blockers txhim kho thiab ua kom tsis muaj zog ntawm Rosinsulin.