Diabeton MV 30 - kev qhia ua qauv rau kev siv
Ib qho ntawm cov xwm txheej tseem ceeb tshaj plaws rau kev kho cov ntshav qab zib kom ua tau zoo yog kev ua kom lub cev nyob ntev. Yog li no, thaum yuav ib tus neeg sawv cev hypoglycemic Diabeton MV 30 mg, cov lus qhia rau kev siv yuav tsum tau ua tib zoo kawm kom thiaj li tiv thaiv tau tus mob.
Raws li cov pab pawg sulfonylurea thib ob, cov tshuaj txo cov ntshav qabzib thiab tshem tawm cov tsos mob ntawm cov ntshav qab zib tsis yog-insulin.
Cov ntaub ntawv tsis txaus siab qhia tias qhov xwm txheej ntawm tus kab mob no tau nce txhua xyoo. Ntau yam ua rau muaj qhov no, tab sis ntawm lawv, cov noob caj noob ces thiab txoj kev ua neej sedentary tsim nyog tshwj xeeb.
Cov tshuaj Diabeton MV 30 mg tsis tsuas yog ua rau theem ntawm glycemia, tab sis kuj tiv thaiv kev txhim kho ntawm ntau yam mob ntshav qab zib, piv txwv li, retinopathy, nephropathy, neuropathy thiab lwm tus. Qhov loj tshaj plaws yog kom paub tias yuav ua li cas kom haus cov tshuaj kom raug, uas yuav sib tham hauv cov ntawv no.
Cov ntaub ntawv siv tshuaj dav dav
Ntshav qab zib MV 30 yog qhov nrov hloov tso tawm hypoglycemic tshuaj thoob ntiaj teb. Nws yog tsim los ntawm lub tuam txhab Fabkis pharmacological Les Laboratoires Servier Іndustrie.
Tus neeg sawv cev hypoglycemic yog siv rau cov ntshav qab zib tsis muaj tshuaj tiv thaiv kab mob ntshav qab zib, thaum kev tawm dag zog lub cev thiab kev noj zaub mov zoo tsis tuaj yeem txo cov ntshav qab zib. Tsis tas li ntawd, ib qho ntawm cov cim qhia rau kev siv tshuaj yog kev tiv thaiv kev mob tshwm sim xws li microvascular (retinopathy thiab / lossis nephropathy) thiab mob macrovascular (mob stroke lossis myocardial infarction).
Lub ntsiab ua haujlwm tseem ceeb ntawm cov tshuaj yog gliclazide - ib sulfonylurea derivative. Tom qab qhov ncauj tswj hwm, qhov feem cuam no yog ua kom xau tag nrho hauv cov hnyuv. Nws cov ntsiab lus nce nce zuj zus, thiab qib siab tau mus txog hauv 6-12 teev. Nws tsim nyog sau cia tias kev noj mov tsis cuam tshuam rau cov tshuaj.
Qhov ua haujlwm ntawm gliclazide yog tsom rau lub zog tsim cov tshuaj insulin los ntawm cov qe hlwb ntawm cov txiav. Tsis tas li ntawd, cov tshuaj muaj cov nyhuv hemovascular, uas yog, nws txo qhov ntxim nyiam ntawm thrombosis hauv cov hlab ntsha me. Gliclazide yog yuav luag tag nrho cov zaub mov hauv lub siab.
Kev zam ntawm cov quav tshwm sim nrog kev pab los ntawm ob lub raum.
Cov lus qhia rau kev siv tshuaj
Cov chaw tsim khoom tsim cov tshuaj hauv daim ntawv ntawm cov ntsiav tshuaj ntawm cov tshuaj sib txawv (30 thiab 60 mg), ntxiv rau, tsuas yog cov neeg mob laus tuaj yeem noj xwb.
Mob ntshav qab zib MV 30 mg tuaj yeem yuav tau hauv lub tsev muag tshuaj nkaus xwb nrog kws kho mob sau ntawv yuav tshuaj. Yog li, tus kws kho mob txiav txim siab qhov ua tau ntawm kev siv cov tshuaj no, muab qib ntawm glycemia thiab lub xeev dav ntawm kev noj qab haus huv ntawm tus neeg mob.
Nws raug nquahu kom noj cov tshuaj ib hnub ib zaug thaum noj mov thaum sawv ntxov. Txhawm rau ua qhov no, lub ntsiav tshuaj yuav tsum nqos thiab ntxuav nrog dej yam tsis muaj kev ntxo. Yog tias tus neeg mob tsis nco qab haus lub ncoo kom ncav sijhawm, muab ob npaug rau koob tshuaj.
Kev muab tshuaj thawj zaug ntawm hypoglycemic yog 30 mg rau ib hnub (1 ntsiav tshuaj). Hauv kev tsis saib xyuas ntshav qab zib, tus txheej txheem no tuaj yeem muab kev tswj kom zoo li cov suab thaj. Txwv tsis pub, tus kws kho mob tus kheej nce qhov ntau ntxiv ntawm cov tshuaj rau tus neeg mob, tab sis tsis ntxov dua tom qab 30 hnub ntawm kev noj thawj zaug. Tus neeg laus pub rau haus ntau li ntau tau hauv ib hnub Diabeton MV 30 txog 120 mg.
Muaj qee cov lus ceeb toom hais txog kev siv cov tshuaj hauv cov neeg muaj hnub nyoog 60 xyoo, nrog rau cov neeg mob kev haus cawv, lub raum lossis lub siab tsis ua haujlwm, piam thaj-6-phosphate dehydrogenase tsis txaus, pituitary lossis adrenal tsis txaus, hlab plawv pathologies thiab hypothyroidism. Hauv cov xwm txheej zoo li no, tus kws tshwj xeeb ua tib zoo xaiv cov tshuaj ntau npaum li cas.
Cov lus qhia txuas nrog hais tias cov tshuaj yuav tsum khaws cia kom txog 30 ° C tsis txhob ncav cuag ntawm cov menyuam yaus. Txee lub neej yuav tsum tau qhia ntawm ntim.
Tom qab lub sijhawm no, kev txwv tsis pub noj tshuaj.
Cov txheej txheem sib tsoo thiab cov phom sij uas yuav muaj
Mob ntshav qab zib MV 30 mg yog contraindicated rau cov neeg mob hnub nyoog qis dua 18 xyoo. Qhov kev txwv no vim yog tsis muaj cov ntaub ntawv qhia txog kev nyab xeeb ntawm cov nyiaj rau menyuam yaus thiab tub ntxhais hluas.
Kuj tseem tsis tau muaj kev siv tus neeg sawv cev hypoglycemic thaum cev xeeb tub thiab lactation. Thaum lub sijhawm nws xeeb tub, qhov kev xaiv zoo tshaj plaws rau kev tswj glycemia yog kev kho tshuaj insulin. Yog tias kev npaj xeeb tub, koj yuav tsum tsum tsis txhob siv cov tshuaj muaj suab thaj thiab hloov mus rau kev txhaj tshuaj hormone.
Ntxiv nrog rau cov lus sau sab saum toj no, phau ntawv qhia kev qhia muaj ntau yam kab mob thiab cov xwm txheej uas Diabeton MV 30 txwv tsis pub siv. Cov no suav nrog:
- mob ntshav qab zib-insulin
- siv cov miconazole kom nruj,
- mob ketoacidosis,
- lub cev sib xyaw rau cov khoom tseem ceeb lossis ntu sib xyaw,
- mob ntshav qab zib coma thiab precoma,
- hepatic thiab / lossis lub raum tsis ua haujlwm (hauv daim ntawv loj).
Raws li qhov tshwm sim ntawm kev siv tsis raug lossis kev siv ntau tshaj, qhov kev xav tsis haum yuav tshwm sim. Yog tias lawv tshwm sim, koj yuav tsum tsis txhob noj cov tshuaj thiab sai nrhiav kev pab ntawm kws kho mob. Koj yuav tsum tsum tsis siv nws yog tias tus neeg mob qhov tsis txaus siab cuam tshuam nrog:
- Nrog ib qho kev poob qis hauv qab zib ntau ntau.
- Nrog rau qhov kev xav ntawm kev tshaib kev nqhis thiab cov rog ntau dua.
- Nrog tsis meej pem thiab tsaus muag.
- Nrog rau kem plab, xeev siab thiab ntuav.
- Nrog mob taub hau thiab kiv taub hau.
- Nrog lub cev tsis muaj zog ntawm kev saib xyuas.
- Nrog ua pa nyuaj.
- Nrog lub qhov muag tsis pom kev thiab hais lus.
- Nrog kev ntxhov siab, txob taus thiab kev poob siab.
- Nrog tshwm sim cov leeg nqaij leeg.
- Nrog ntshav siab.
- Nrog bradycardia, tachycardia, angina pectoris.
- Nrog kev kho mob ntawm daim tawv nqaij (khaus, tawm pob, erythema, urticaria, Quincke edema).
- Nrog kev thab plaub ua heev.
- Nrog nce hws.
Cov paib tseem ceeb ntawm kev noj ntau dua yog qhov ua rau ntshav qab zib, uas tuaj yeem raug tshem tawm nrog cov zaub mov muaj txiaj ntsig ntawm kev zom cov zaub mov muaj txiaj ntsig (qab zib, chocolate, txiv hmab txiv ntoo qab zib). Hauv daim ntawv foos hnyav dua, thaum tus neeg mob yuav poob siab lossis poob rov qab, nws yuav tsum tau maj nrawm rau hauv tsev kho mob. Ib txoj kev ua haujlwm rau cov ntshav qab zib yog los ntawm kev tswj cov piam thaj. Yog tias tsim nyog, kev kho mob cov tsos mob yog nqa tawm.
Kev sib xyaw nrog lwm txoj kev
Thaum muaj cov kab mob sib kis, nws yog ib qho tseem ceeb rau tus neeg mob kom qhia qhov no rau nws tus kws kho mob tshwj xeeb. Kev tuav tseg cov ntaub ntawv tseem ceeb no tuaj yeem cuam tshuam rau txoj kev cuam tshuam ntawm cov tshuaj Diabeton MV 30 nws tus kheej.
Raws li koj paub, muaj ib tug xov tooj ntawm cov tshuaj uas tuaj yeem txhim kho lossis, hloov pauv, tsis muaj zog cov txiaj ntsig ntawm ib tus neeg sawv cev hypoglycemic. Qee qhov ntawm lawv tuaj yeem ua rau lwm yam tsis xav tau yam tsis xav tau.
Cov tshuaj thiab cov cheeb tsam uas ua rau muaj qhov txo qis ntau dua:
- Miconazole
- Phenylbutazone
- Ethanol
- Sulfonamides.
- Thiazolidinidones.
- Acarbose.
- Cov tshuaj insulin ultrasonic.
- Cov tshuaj nonsteroidal anti-inflammatory.
- Clarithromycin
- Metformin.
- GPP-1 agonists.
- MAO inhibitors.
- Dipeptidyl peptidase-4 inhibitors.
- Beta blockers.
- ACE inhibitors.
- Fluconazole
- H2-histamine receptor blockers.
Cov tshuaj thiab cov cheeb tsam uas ua rau muaj kev pheej hmoo ntawm hyperglycemia:
- Danazole
- Chlorpromazine
- Glucocorticosteroids,
- Tetracosactide,
- Salbutamol,
- Ritodrin
- Terbutaline.
Nws yuav tsum raug sau tseg tias kev tswj hwm tib lub sij hawm ntawm sulfonylurea derivatives thiab anticoagulants tuaj yeem txhim kho cov nyhuv tom kawg. Yog li ntawd, qee kis, nws yog qhov tsim nyog yuav tau kho lawv cov ntau npaum li cas.
Txhawm rau kom tsis txhob muaj qhov tshwm sim tsis zoo, tus neeg mob yuav tsum tau mus cuag tus kws tshaj lij uas tuaj yeem ntsuas tau qhov sib cuam tshuam ntawm cov tshuaj.
Qhov tseeb cuam tshuam rau qhov ua tau zoo ntawm cov tshuaj
Tsis tsuas yog noj tshuaj los yog noj tshuaj ntau dhau tuaj yeem cuam tshuam rau cov txiaj ntsig ntawm cov ntshav qab zib hypoglycemic tus neeg sawv cev MV 30. Muaj ntau ntau yam cuam tshuam uas cuam tshuam rau kev noj qab haus huv ntawm cov ntshav qab zib.
Qhov thib ib thiab qhov laj thawj feem ntau rau kev kho mob tsis txaus ntseeg yog qhov tsis kam los yog tsis muaj peev xwm ntawm cov neeg mob (tshwj xeeb yog cov neeg laus) tswj hwm lawv kev noj qab haus huv thiab ua raws txhua cov lus pom zoo ntawm tus kws kho mob.
Qhov thib ob, qhov tseem ceeb zoo ib yam yog kev noj haus tsis xwm yeem lossis kev noj zaub mov tsis xwm yeem. Tsis tas li ntawd, qhov kev ua tau zoo ntawm cov tshuaj cuam tshuam los ntawm kev tshaib plab, qhov tsis txaus nyob hauv kev nkag thiab hloov pauv kev noj haus ib txwm.
Tsis tas li ntawd, rau kev kho mob kom tiav, tus neeg mob yuav tsum tswj hwm cov nyiaj uas tau los ntawm carbohydrates noj thiab kev siv lub cev. Txhua yam kev hloov pauv tsis zoo cuam tshuam rau cov ntshav qab zib thiab kev noj qab haus huv.
Yog lawm, cov kab mob concomitant ua lub luag haujlwm tseem ceeb. Ua ntej tshaj plaws, cov no yog cov kab mob endocrine cuam tshuam nrog cov thyroid caj pas thiab cov qog pituitary, nrog rau mob raum thiab mob rau lub siab.
Yog li, thiaj li ua tiav qhov ntsuas lub ntsej muag muaj txiaj ntsig thiab tshem tawm cov tsos mob ntshav qab zib, tus neeg mob thiab nws tus kws kho mob tshwj xeeb yuav tsum kov yeej lossis tsawg kawg yog ua kom yam ntxwv ntawm cov yam ntxwv saum toj no.
Nqi, tshuaj xyuas thiab analogues
Cov tshuaj Diabeton MV 30 mg tuaj yeem yuav ntawm txhua lub tsev muag tshuaj lossis xaj online ntawm lub vev xaib ntawm tus neeg muag khoom. Tus nqi ntawm cov tshuaj yog nyob ntawm tus naj npawb ntawm cov ntsiav tshuaj hauv pob. Yog li, tus nqi ntawm ib pob uas muaj 30 ntsiav tshuaj ntawm 30 mg rau txhua thaj tsam ntawm 255 txog 288 rubles, thiab tus nqi ntawm ib pob muaj 60 ntsiav tshuaj ntawm 30 mg rau ib qho twg los ntawm 300 txog 340 rubles.
Raws li koj tuaj yeem pom, cov tshuaj muaj rau tus neeg mob nrog txhua qib nyiaj tau los, uas, tau kawg, yog ib qho loj ntxiv. Tom qab kuaj xyuas qhov kev soj ntsuam zoo ntawm tus mob ntshav qab zib, peb tuaj yeem kos qee qhov kev txiav txim siab txog cov tshuaj no:
- Yooj yim ntawm kev siv nrog rau cov tshuaj insulin.
- Tsis tshua muaj mob tshwm sim tsis zoo.
- Kev ruaj khov ntawm glycemia.
Txawm li cas los xij, nyob rau qee qhov xwm txheej, tau muaj kev poob qis hauv cov piam thaj kom sai, uas tau raug tshem tawm los ntawm kev noj zaub mov carbohydrates. Feem ntau, txoj kev xav ntawm cov kws kho mob thiab cov neeg mob txog cov tshuaj muaj qhov zoo. Nrog rau kev siv txoj cai ntawm cov ntsiav tshuaj thiab ua raws txhua tus kws kho mob cov lus qhia, koj tuaj yeem ua tiav cov piam thaj li qub thiab zam kev phiv. Nws yuav tsum nco ntsoov tias tsuas yog cov neeg mob uas:
- ua raws li kev noj haus zoo,
- ncaws pob ncaws pob
- ua kom muaj kev sib npaug ntawm kev so thiab kev ua haujlwm,
- tswj qabzib
- sim ua kom tsis txhob muaj kev npau taws thiab kev ntxhov siab.
Qee tus neeg siv cov tshuaj hauv kev tawm dag zog kom nce cov leeg nqaij. Txawm li cas los xij, cov kws kho mob ceeb toom siv cov tshuaj rau lwm lub hom phiaj.
Nrog rau kev txhim kho ntawm kev tsis zoo los yog hauv kev sib txuas nrog contraindications, tus kws kho mob muaj teeb meem nrog kev xaiv ntawm lwm cov tshuaj uas yuav muaj cov kev kho mob zoo sib xws. Diabeton MV muaj ntau yam. Piv txwv li, ntawm cov tshuaj uas muaj cov nquag tiv thaiv gliclazide, nrov tshaj plaws yog:
- Glidiab MV (140 rubles),
- Glyclazide MV (130 rubles),
- Diabetalong (105 rubles),
- Diabefarm MV (125 rubles).
Ntawm cov kev npaj muaj lwm yam tshuaj, tab sis muaj tib lub txiaj ntsig hypoglycemic, ib qho tuaj yeem paub qhov txawv Glemaz, Amaril, Gliclada, Glimepirid, Glyurenorm, Diamerid thiab lwm tus.
Nws yog tsim nyog sau cia tias thaum xaiv cov tshuaj, tus neeg mob them nqi tsis yog rau nws cov txiaj ntsig, tab sis kuj nws tus nqi. Coob tus naj npawb ntawm cov analogues ua rau nws tuaj yeem xaiv qhov kev xaiv zoo tshaj plaws rau cov lus piv ntawm cov nqi thiab zoo.
Diabeton MV 30 mg - ib qho cuab yeej siv hauv kev kho mob ntshav qab zib hom 2. Thaum siv kom raug, cov tshuaj yuav pab txo cov ntshav qab zib thiab tsis nco qab txog cov cim ntawm "tus kab mob qab zib" ntev ntev. Qhov loj tshaj plaws yog tsis txhob hnov qab txog tus kws kho mob cov lus qhia thiab ua lub neej noj qab haus huv.
Tus kws tshaj lij los ntawm daim vis dis aus hauv tsab xov xwm no yuav tham txog cov ntsiab lus ntawm tus kws kho mob ntshav qab zib.
Daim ntawv noj tshuaj:
Muaj pes tsawg leeg:
Muaj ib ntsiav tshuaj:
Yam tshuaj muaj sia: gliclazide - 30.0 mg.
Cov muaj tswv yim: calcium hydrogen phosphate dihydrate 83.64 mg, hypromellose 100 cP 18.0 mg, hypromellose 4000 cP 16.0 mg, magnesium stearate 0.8 mg, maltodextrin 11.24 mg, anhydrous colloidal silicon dioxide 0.32 mg.
Kev piav qhia
Dawb, biconvex oval ntsiav tshuaj sau nrog "DIA 30" ntawm ib sab thiab tuam txhab logo ntawm lwm.
Pab pawg kws tshuaj:
PHARMACOLOGICAL COV CAI
Cov Tshuaj Hauv Tshuaj
Glyclazide yog sulfonylurea derivative, hypoglycemic tshuaj rau qhov ncauj tswj hwm, uas sib txawv los ntawm cov tshuaj zoo sib xws los ntawm qhov muaj tus N - muaj cov ntiv nplhaib heterocyclic nrog kev sib khi endocyclic.
Glyclazide txo qis kev xav ntawm cov ntshav qabzib, txhawb kev tso pa tawm ntawm insulin los ntawm b-cell ntawm islets ntawm Langerhans. Kev nce siab ntawm cov tshuaj tom qab tawm insulin thiab C-peptide mob tsawv tom qab 2 xyoos dhau los ntawm kev kho.
Ntxiv nrog rau cov nyhuv ntawm cov metabolism hauv cov metabolism, gliclazide muaj cov teebmeem hemovascular.
Ntxim rau insulin secretion
Hauv hom 2 mob ntshav qab zib mellitus, cov tshuaj rov qab ua rau lub sijhawm thaum kawg ntawm cov kua dej hauv cov kua dej hauv cov lus teb rau cov piam thaj thiab ua rau qib thib ob ntawm insulin secretion. Ib qho tseem ceeb nce ntxiv ntawm insulin secretion tau pom nyob rau hauv teb rau kev tsa ua vim kev noj zaub mov ntau dua lossis cov tshuaj tswj cov piam thaj.
Hemovascular cov teebmeem
Glyclazide txo txoj kev pheej hmoo ntawm cov ntshav me me kom tsis muaj teeb meem, muaj feem cuam tshuam rau cov txheej txheem uas tuaj yeem ua rau muaj kev txhim kho ntawm kev mob ntshav qab zib mellitus: ib feem ntawm kev ua kom tsis muaj platelet thiab kev ua kom tiav thiab ib qho kev txo qis ntawm kev ua kom cov platelet ua kom muaj lwm yam (beta-thromboglobulin, thromboxane B2), nrog rau kev rov qab ua haujlwm ntawm fibrinolytic vascular nce kev ua si ntawm cov nqaij mos plasminogen activator.
Kev siv tshuaj tiv thaiv zoo glycemic raws li kev siv Diabeton® MV (HbA1c Lub tswv yim ntawm kev siv tshuaj tiv thaiv zoo glycemic suav nrog kev teem sijhawm rau tshuaj Diabeton® MV thiab nce nws qhov kev siv tshuaj tiv thaiv cov keeb kwm yav dhau los ntawm (lossis hloov) kev kho mob ua ntej ntxiv rau nws lwm cov tshuaj hypoglycemic (piv txwv li, metformin, ib qho alpha-glucosidase inhibitor) , qhov tsim tawm ntawm thiazolidinedione lossis tshuaj insulin.) Qhov nruab nrab txhua hnub ntawm cov tshuaj Diabeton® MV hauv cov neeg mob hauv cov pab pawg tswj hwm tau yog 103 mg, qhov siab tshaj plaws txhua hnub koob tshuaj yog 120 mg.
Tawm tsam cov keeb kwm yav dhau los ntawm kev siv tshuaj yeeb tshuaj Diabeton ® MV nyob rau hauv kev tswj hwm glycemic tswj (kev soj qab taug qab lub sijhawm 4.8 xyoo, nruab nrab HbA1c qib 6.5%) piv nrog pawg tswj hwm (nruab nrab HbA1c qib 7.3%), qhov txo qis 10% yog pom cov kev pheej hmoo sib piv ntawm cov kev sib xyaw ua ke ntawm macro- thiab cov teeb meem microvascular
Qhov kom zoo dua tau ua tiav los ntawm kev txo tus mob sib piv: loj microvascular teeb meem los ntawm 14%, qhov pib thiab kev loj hlob ntawm nephropathy los ntawm 21%, qhov tshwm sim ntawm microalbuminuria los ntawm 9%, macroalbuminuria los ntawm 30% thiab kev txhim kho lub raum mob ntxiv los ntawm 11%.
Cov txiaj ntsig ntawm kev tswj hwm glycemic thaum noj Diabeton® MV tsis vam khom rau cov txiaj ntsig tau ua tiav nrog kev kho mob.
Cov Tshuaj Pharmacokinetics
Tom qab lub qhov ncauj tswj hwm, gliclazide yog kiag li kev nqus. Qhov kub siab ntawm gliclazide hauv plasma nce ntau zuj zus, mus txog toj siab tom qab 6-12 teev. Cov tib neeg txawv txav yog tsawg.
Kev noj mov tsis cuam tshuam rau qib ntawm kev nqus ntawm cov tshuaj. Cov kev sib raug zoo ntawm cov koob tshuaj tiv thaiv (txog 120 mg) thiab thaj chaw hauv qab qhov nkhaus pharmacokinetic "concentration-sijhawm" yog kab. Kwv yees li 95% ntawm cov tshuaj khi rau cov ntshav plasma. Glyclazide yog metabolized feem ntau hauv lub siab thiab raug tso tawm feem ntau los ntawm lub raum: kev nthuav tawm yog nqa tawm hauv daim ntawv ntawm cov tshuaj metabolites, tsawg dua 1% yog tawm los ntawm lub raum tsis hloov. Tsis muaj cov metabolites hauv lub plasma ntshav.
Ib nrab-lub neej ntawm gliclazide yog nruab nrab li ntawm 12 txog 20 teev. Qhov ntim ntawm kev xa tawm yog li 30 litres.
Hauv cov neeg laus, tsis muaj kev hloov pauv ntau hauv cov qauv pharmacokinetic.
Kev noj cov tshuaj Diabeton ® MV hauv ib koob tshuaj 30 mg ib hnub ib zaug ua rau muaj kev saib xyuas ntawm kev ua hauj lwm zoo ntawm gliclazide hauv cov ntshav ntshav rau ntau dua 24 teev.
INDICATIONS RAU SIV
Hom 2 mob ntshav qab zib mellitus nrog cov tsis muaj txiaj ntsig ntawm kev kho zaub mov noj, ua kom lub cev thiab yuag poob.
Kev tiv thaiv ntawm cov teeb meem mob ntshav qab zib mellitus: txo kev pheej hmoo ntawm microvascular (nephropathy, retinopathy) thiab macrovascular muaj teeb meem (myocardial infarction, mob stroke) hauv cov neeg mob hom 2 mob ntshav qab zib mellitus los ntawm kev tswj hwm zoo glycemic.
- cov tshuaj tiv thaiv kab mob rau gliclazide, lwm yam sulfonylurea derivatives, sulfonamides lossis rau cov neeg raug tshem tawm uas yog ib feem ntawm cov tshuaj,
- ntshav qab zib hom 1
- ketoacidosis, mob ntshav qab zib precoma, mob ntshav qab zib coma,
- mob raum lossis lub siab ua haujlwm tsis zoo (hauv cov teeb meem no, nws raug nquahu kom siv cov insulin)
- concomitant kev kho mob nrog miconazole (saib ntu "Kev cuam tshuam nrog lwm cov tshuaj"),
- cev xeeb tub thiab lub sijhawm lactation (saib ntu "Cev xeeb tub thiab lub sijhawm lactation"),
- hnub nyoog txog 18 xyoo.
Nws tsis pom zoo kom siv los ua ke nrog phenylbutazone thiab danazole (saib ntu "Kev cuam tshuam nrog lwm cov tshuaj").
Nrog saib xyuas:
Cov neeg laus, tsis xwm yeem thiab / lossis tsis noj zaub mov tsis zoo, qabzib-6-phosphate dehydrogenase tsis txaus, cov kab mob hnyav ntawm cov hlab plawv, hypothyroidism, adrenal lossis pituitary tsis txaus, lub raum thiab / lossis daim siab tsis ua haujlwm, ntev kho nrog glucocorticosteroids (GCS), kev quav dej cawv.
PREGNANCY THIAB BREAST-FEEDING PERIOD
Cev xeeb tub
Tsis muaj kev paub nrog gliclazide thaum cev xeeb tub. Cov ntaub ntawv hais txog kev siv lwm cov sulfonylurea derivatives thaum cev xeeb tub muaj tsawg.
Hauv kev kawm txog cov tsiaj hauv chaw sim, teratogenic cov teebmeem ntawm gliclazide tsis tau txheeb xyuas.
Txhawm rau kom txo cov kev pheej hmoo ntawm lub cev tsis xwm yeem, kev tswj hwm qib siab (kev kho kom haum) ntawm ntshav qab zib mellitus yog qhov tsim nyog.
Qhov ncauj hypoglycemic qhov ncauj thaum cev xeeb tub tsis siv.
Cov tshuaj Insulin yog cov tshuaj xaiv rau kev kho mob ntshav qab zib hauv cov poj niam cev xeeb tub.
Nws raug nquahu kom hloov qhov kev noj tshuaj ntawm qhov ncauj hypoglycemic nrog insulin txoj kev kho ob leeg nyob rau hauv rooj plaub ntawm kev npaj cev xeeb tub, thiab yog tias cev xeeb tub tau tshwm sim thaum noj cov tshuaj.
Lactation
Ua tib zoo xav txog qhov tsis muaj cov ntaub ntawv hais txog kev noj cov gliclazide hauv cov kua mis thiab kev pheej hmoo los ntawm kev mob ntshav qab zib hauv menyuam txoj kev pub mis, kev pub mis rau tus menyuam yog contraindicated thaum kho nrog cov tshuaj no.
KHAWV KOOB THIAB KEV COB QHIA
DAIM AV RAU QHOV KEV SIV RAU XWB RAU KEV TIV THAIV NEEG.
Qhov pom zoo koob tshuaj (1-4 ntsiav tshuaj, 30-120 mg) yuav tsum noj qhov ncauj, 1 zaug nyob rau ib hnub, nyiam dua thaum noj tshais.
Nws raug nquahu kom cov ntsiav tshuaj nqos tag nrho yam tsis muaj ntxo lossis ntxau.
Yog tias koj plam ib lossis ntau dua ntawm cov tshuaj, koj tsis tuaj yeem siv ntau dua koob tshuaj ntxiv, koob tshuaj uas ploj lawm yuav tsum noj nyob rau hnub tom ntej.
Ib yam li lwm cov tshuaj ntshav hypoglycemic, cov koob tshuaj hauv txhua kis yuav tsum tau xaiv ib tus zuj zus, nyob ntawm kev saib xyuas cov ntshav qabzib thiab glycosylated hemoglobin (HbA1c).
Thawj koob tshuaj
Thawj koob tshuaj pom zoo (suav nrog rau cov neeg mob laus, ≥ 65 xyoo) yog 30 mg rau ib hnub.
Thaum muaj kev tswjhwm txaus, cov tshuaj hauv qhov tshuaj no tuaj yeem siv rau kev kho kho. Nrog kev tswj tsis tau glycemic txaus, koob tshuaj txhua hnub tuaj yeem raug nce ntxiv mus rau 60, 90 lossis 120 mg.
Qhov koob tshuaj nce siab yog ua tau tsis tau ntxov dua tom qab 1 lub hlis ntawm kev siv tshuaj kho nyob rau ntawm lub koob tshuaj uas tau qhia dhau los. Qhov tshwj tsis yog cov neeg mob uas cov ntshav qabzib concentration tsis tau txo tom qab 2 lub lis piam ntawm kev kho. Nyob rau hauv cov xwm txheej zoo li no, cov koob tshuaj yuav raug nce 2 lub lis piam tom qab pib ua haujlwm.
Qhov siab tshaj plaws uas pom zoo hauv kev siv tshuaj txhua hnub yog 120 mg.
Hloov los ntawm tus kab mob ntshav qab zib ® 80 mg ntsiav tshuaj rau ib hom tshuaj ntshav qab zib ® 30 mg hloov-tso tawm ntsiav tshuaj
1 ntsiav tshuaj ntawm cov tshuaj Diabeton ® 80 mg tuaj yeem hloov los ntawm 1 ntsiav tshuaj nrog hloov kho tso tawm Diabeton ® MV 30 mg. Thaum hloov mus rau cov neeg mob ntshav qab zib ® 80 mg rau Diabeton D MV, ceev faj kev tswj glycemic yog pom zoo.
Hloov los ntawm lwm cov tshuaj hypoglycemic rau Diabeton ® 30 mg hloov-tso tawm ntsiav tshuaj
Cov tshuaj Diabeton ® MV cov ntsiav tshuaj nrog hloov pauv ntawm 30 mg tuaj yeem siv hloov lwm lub tshuaj hypoglycemic rau kev tswj hwm qhov ncauj. Thaum hloov mus rau cov neeg mob tau txais lwm cov tshuaj hypoglycemic rau kev tswj hwm qhov ncauj rau Diabeton ® MV, lawv cov koob tshuaj thiab ib nrab ntawm lub neej yuav tsum raug coj los txiav txim. Raws li txoj cai, lub sijhawm hloov pauv tsis tas yuav tsum muaj.
Qhov muab tshuaj thawj zaug yuav tsum yog 30 mg thiab tom qab ntawv ua raws li lub siab ntawm cov ntshav qabzib.
Thaum Tus Mob Ntshav Qab Zib ® MV hloov pauv nrog sulfonylurea derivatives nrog ib nrab lub neej ntev kom tsis txhob mob ntshav qab zib vim tshwm sim los ntawm cov nyhuv ntxiv ntawm ob tus kab mob hypoglycemic, koj tuaj yeem nres noj lawv rau ob peb hnub. Qhov pib txhaj tshuaj Diabeton ® MV tib lub sijhawm kuj yog 30 mg thiab, yog tias tsim nyog, tuaj yeem nce ntxiv yav tom ntej, raws li tau piav qhia saum toj no.
Ua ke siv nrog lwm cov tshuaj hypoglycemic
Tus mob ntshav qab zib ® MB tuaj yeem siv nrog kev sib xyaw nrog loj loj, alpha-glucosidase inhibitors lossis insulin.
Nrog kev tswj tsis tau glycemic tsis txaus, kev kho tshuaj insulin ntxiv yuav tsum tau txiav txim siab nrog kev saib xyuas mob siab.
Cov neeg laus cov neeg mob
Kev txhaj tshuaj rau cov neeg mob uas laus dua 65 xyoos tsis tas yuav tsum tau ua.
Cov neeg mob raum tsis ua haujlwm Cov txiaj ntsig ntawm kev tshawb fawb pom tau hais tias kev kho kom haum rau hauv cov neeg mob uas tsis tshua mob mus rau lub raum tsis ua haujlwm. Pom zoo kev saib xyuas kev mob nkeeg.
Cov neeg mob Yuav Muaj Kev Phom Sij Hypoglycemia
Hauv cov neeg mob uas muaj kev pheej hmoo txhim kho hypoglycemia (noj tsis txaus lossis tsis noj zaub mov noj tsis txaus, mob hnyav lossis nyiaj tsis txaus ntawm cov kabmob endocrine - pituitary thiab adrenal tsis txaus, hypothyroidism, tshem tawm cov glucocorticosteroids (GCS) tom qab siv sijhawm ntev thiab / lossis kev tswj hwm hauv siab, mob ntshav siab ntau vascular system - muaj kev mob plawv mob ntshav siab, mob hnyav carotid arteriosclerosis, mob atherosclerosis zoo tshaj plaws, nws raug nquahu kom siv tshuaj tsawg kawg (30 mg) ntawm kev npaj ua ntej ata Diabeton ® MV.
Tiv thaiv tus mob ntshav qab zib muaj teeb meem
Txhawm rau kom muaj kev sib deev ntau ntxiv glycemic tswj, koj tuaj yeem maj mam nce qhov ntau ntawm cov tshuaj Diabeton ® MV rau 120 mg / hnub ntxiv rau kev noj haus thiab kev tawm dag zog kom ua tiav cov hom phiaj ntawm HbA1c. Nco ntsoov cov kev pheej hmoo ntawm kev txhim kho hypoglycemia. Tsis tas li ntawd, lwm cov tshuaj hypoglycemic, piv txwv li, metformin, ib qho alpha glucosidase nigibitor, thiazolidinedione derivative lossis insulin, tuaj yeem raug ntxiv rau kev kho mob.
Cov menyuam yaus thiab cov tub ntxhais hluas hnub nyoog qis dua 18 xyoo.
Cov ntaub ntawv hais txog kev ua haujlwm zoo thiab muaj kev nyab xeeb rau cov tshuaj hauv cov menyuam yaus thiab cov hluas hnub nyoog qis dua 18 xyoo tsis muaj.
Tej yam tsis zoo
Muab cov kev paub dhau los nrog gliclazide thiab lwm yam sulfonylurea derivatives, cov kev mob tshwm sim hauv qab no yuav tsum raug txiav txim siab.
Kev ntshav siab
Zoo li lwm yam tshuaj ntawm sulfonylurea pab pawg, Diabeton ® MV tuaj yeem ua rau tus mob ntshav qab zib tsawg yog tias zaub mov tsis haum thiab tshwj xeeb yog tias qhov khoom noj tsis txaus. Cov tsos mob tshwm sim ntawm tus mob ntshav qab zib: mob taub hau, tshaib plab, xeev siab, ntuav, ntau zog, pw tsaug zog, chim siab, ntxhov siab, tsis tshua mloog siab, ncua tshuaj tiv thaiv, kev nyuaj siab, tsis meej pem, tsis pom kev thiab hais lus, tsis meej pem, tshee, paresis, tsis hnov qab , kiv taub hau, tsis muaj zog, hnov dab tsi, khuam plhaw, ua kom zoo nkauj, ua pa tsis ua hauj lwm, poob tsaug zog, tsis nco qab nrog txoj kev txhim kho mob tsis nco qab, mus txog hnub tuag.
Cov tshuaj tiv thaiv Andrenergic tseem tuaj yeem sau tseg: nce hws, "tawv nqaij" tawv nqaij, ntxhov siab, tachycardia, nce ntshav siab, palpitations, arrhythmia, thiab angina pectoris.
Raws li txoj cai, cov tsos mob hypoglycemia tau nres los ntawm kev noj cov khoom noj carbohydrates (qab zib).
Noj cov khoom qab zib yog qhov ua tsis tau txiaj ntsig. Tawm tsam keeb kwm ntawm lwm cov sulfonylurea derivatives, rov qab kho cov ntshav qog ntshav tau sau tseg tom qab nws tau txais txiaj ntsig zoo.
Thaum mob ntshav qab zib tsawg los yog lub caij ntev, kev kho mob xwm txheej ceev tau qhia, tejzaum nws yuav tsum tau pw hauv tsev kho mob, txawm hais tias muaj qhov cuam tshuam los ntawm kev noj cov zaubmov nyiaj.
Lwm yam phiv
- Los ntawm lub plab zom mov: mob plab, xeev siab, ntuav, raws plab, cem quav. Kev noj cov tshuaj thaum noj tshais zam cov tsos mob no lossis txo qis.
Cov kev mob tshwm sim nram qab no tsis tshua pom:
- Ntawm ib feem ntawm daim tawv nqaij thiab cov nqaij mos subcutaneous: pob khaus, khaus, urticaria, erythema, maculopapullous pob, ua pob ua pob.
- Los ntawm cov ntshav ncig thiab cov qog ua ntshav: hematological mob (ntshav liab, leukopenia, thrombocytopenia, granulocytopenia) muaj tsawg. Raws li txoj cai, cov xwm txheej no thim rov qab yog tias kev kho tsis ua hauj lwm.
- Ntawm ib feem ntawm daim siab thiab nplooj siab txoj hnyuv: nce kev ua haujlwm ntawm "daim siab" enzymes (aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase), kab mob siab (mob cais tawm). Yog tias muaj tus mob daj ntseg cholestatic tshwm sim, kev kho yuav tsum tsis ua mus ntxiv.
Cov kev mob tshwm sim nram qab no feem ntau yuav thim rov qab yog tias kev kho tsis ua hauj lwm.
- Los ntawm ob sab ntawm cov khoom hauv nruab nrog ntawm lub zeem muag: thaj tsam cuam tshuam txog lub ntsej muag yuav tshwm sim vim yog qhov hloov pauv ntawm cov concentration ntawm cov ntshav qab zib, tshwj xeeb tshaj yog thaum pib kho.
- Cov kev mob tshwm sim los ntawm sulfonylurea derivatives: thaum noj lwm yam sulfonylurea derivatives, cov kev mob tshwm sim hauv qab no tau sau tseg: erythrocytopenia, agranulocytosis, hemolytic anemia, pancytopenia, kev tsis haum vasculitis thiab hyponatremia. Muaj kev nce ntxiv hauv cov kev ua haujlwm ntawm "daim siab" ua rau lub siab ua haujlwm tsis zoo, piv txwv li, nrog kev loj hlob ntawm cholestasis thiab jaundice thiab mob siab, tshwm sim tsawg dua lub sijhawm tom qab kev noj qab haus huv ntawm sulfonylurea kev npaj, tab sis qee kis tau ua rau lub siab ua rau lub siab tsis ua haujlwm.
Sab kev tshwm sim muaj nyob rau hauv kev soj ntsuam kuaj mob
Hauv qhov kev tshawb nrhiav ADVANCE, muaj qhov sib txawv me me hauv qhov nquag ntawm ntau qhov xwm txheej tsis zoo ntawm ob pawg ntawm cov neeg mob. Tsis muaj cov ntaub ntawv kev nyab xeeb tshiab tau txais. Tsawg tsawg tus neeg mob tau muaj ntshav qab zib ntau ntau, tab sis qhov xwm txheej ntawm tag nrho cov neeg mob ntshav qab zib tsawg tsawg. Qhov tshwm sim ntawm cov ntshav qog nqaij hlav hauv ntshav siab glycemic tswj pab pawg tau siab dua nyob hauv pawg glycemic tswj pawg. Feem ntau qhov tshwm sim ntawm hypoglycemia nyob rau hauv kev tswj hwm glycemic tau tsom kwm tawm tsam keeb kwm ntawm cov tshuaj insulin kho.
OVERDOSE
Yog tias muaj kev noj tshuaj ntau dhau ntawm sulfonylurea derivatives, hypoglycemia yuav loj hlob tuaj.
Yog tias koj muaj cov tsos mob me me ntawm lub cev tsis muaj ntshav tsis muaj qhov tsis nco qab los yog cov tsos mob ntawm lub paj hlwb, koj yuav tsum nce cov khoom noj carbohydrates nrog cov zaub mov, txo qhov ntau ntawm cov tshuaj thiab / lossis hloov cov zaub mov noj. Kaw kev tshuaj xyuas mob ntawm tus neeg mob yuav tsum tau txuas ntxiv mus kom txog thaum muaj kev ntseeg siab tias tsis muaj dab tsi ua rau nws noj qab haus huv.
Tej zaum qhov kev txhim kho ntawm cov kev mob hypoglycemic hnyav, nrog kev tsis nco qab, ntog lossis lwm yam mob puas siab ntsws. Yog tias cov tsos mob no tshwm sim, yuav tsum tau txais kev kho mob ceev ceev thiab tau mus pw hauv tsev kho mob sai.
Yog tias qhov mob ntshav qab zib tsis tsaug zog lossis yog xav tias tsam tus neeg mob txhaj tshuaj rau 50 ml ntawm 20-30% dextrose (kua nplaum) tov. Tom qab ntawv, ib qho 10% dextrose kev daws teeb meem yog muab tshuaj txo qis kom tswj tau cov ntshav qabzib siab siab tshaj 1 g / L. Kev saib zoo ntawm cov ntshav qabzib concentration thiab tshuaj xyuas ntawm tus neeg mob yuav tsum tau nqa tawm tsawg kawg 48 teev tom qab.
Tom qab lub sijhawm no, nyob ntawm tus neeg mob lub sijhawm, tus kws kho mob txiav txim siab txog qhov xav tau kev tshuaj xyuas ntxiv. Kev lim ntshav tsis muaj txiaj ntsig vim yog qhov tseeb khi ntawm gliclazide ntxiv rau cov ntshav protein.
INTERACTION NROG LWM COV MEDICINES
1) Cov tshuaj uas ua rau muaj kev phom sij ntawm hypoglycemia:
(txhim kho cov nyhuv ntawm gliclazide)
Contraindicated kev sib txuas ua ke
- Miconazole (nrog kev tswj hwm kev ua haujlwm zoo thiab thaum siv lub ntsej muag rau ntawm lub qhov ncauj mucosa): ua kom lub ntsej muag hypoglycemic ntawm gliclazide (hypoglycemia yuav dhau mus txog thaum tsis nco qab).
Tsis pom zoo kev sib txuas ua ke
- Phenylbutazone (kev tswj hwm kev tswj hwm): txhim kho cov nyhuv hypoglycemic ntawm sulfonylurea derivatives (tshem tawm lawv los ntawm kev sib txuas lus nrog plasma protein thiab / lossis ua rau qeeb kev txiav tawm ntawm lub cev).
Nws zoo dua yog siv lwm cov tshuaj tiv thaiv kev tiv thaiv. Yog tias phenylbutazone tsim nyog, tus neeg mob yuav tsum ceeb toom txog qhov xav tau kev tswj hwm glycemic. Yog tias tsim nyog, cov koob tshuaj ntawm cov tshuaj Diabeton ® MV yuav tsum tau kho thaum noj phenylbutazone thiab tom qab nws.
- Ethanol: txhim kho cov ntshav qog ntshav qab zib, kev tiv thaiv tiv thaiv kev ua txhaum, tuaj yeem pab txhawb kev txhim kho hypoglycemic coma. Nws yog ib qho tsim nyog kom tsis kam noj tshuaj, uas suav nrog kev haus cawv thiab haus cawv.
Ceev faj
Gliclazide ua ke nrog qee yam tshuaj (piv txwv li, lwm yam kab mob hypoglycemic - insulin, alpha glucosidase inhibitor, biguanides, beta-blockers, fluconazole, angiotensin-hloov mus rau enzyme inhibitors - captopril, enalapril, H2S-histamine inhibitors, non-histamine inhibitors) anti-inflammatory tshuaj) yog nrog los ntawm kev nce hauv cov nyhuv hypoglycemic thiab kev pheej hmoo ntawm hypoglycemia.
2) Cov tshuaj uas ua rau cov ntshav ntxiv ntshav:
(cov nyhuv tsis muaj zog ntawm gliclazide)
Tsis pom zoo kev sib txuas ua ke
- Danazole: muaj ib tug mob ntshav qab zib ua hauj lwm. Nyob rau hauv kev tshwm sim uas kev siv cov tshuaj no yog qhov tsim nyog, tus neeg mob raug pom zoo saib xyuas glycemic. Yog tias tsim nyog, kev sib koom tes ua ke ntawm cov tshuaj, nws raug nquahu tias koob tshuaj hypoglycemic tus neeg sawv cev yuav tsum tau xaiv ob qho tib si thaum tswj hwm ntawm danazol thiab tom qab nws tshem tawm.
Ceev faj
- Chlorpromazine (antipsychotic): hauv kev txhaj tshuaj ntau (ntau tshaj 100 mg rau ib hnub) ua rau muaj qhov nce ntxiv ntawm cov piam thaj hauv cov ntshav, txo qis cov tshuaj insulin.
Ua tib zoo glycemic tswj hwm yog pom zoo. Yog tias tsim nyog, kev sib koom tes tswj hwm tshuaj, nws raug pom zoo tias yuav tsum tau xaiv cov koob tshuaj hypoglycemic, ob qho tib si thaum tswj hwm kev tawm tsam thiab tom qab tshem tawm.
- GKS (kev kaw lus hauv ib cheeb tsam thiab daim ntawv thov hauv ib cheeb tsam: thaj tsam ntawm daim tawv nqaij, tawv nqaij, lub qhov quav): ua rau kom cov ntshav qabzib ntau ntxiv nrog kev txhim kho ketoacidosis (txo qis hauv kam rau ua carbohydrates). Saib xyuas glycemic tswj hwm yog pom zoo, tshwj xeeb tshaj yog thaum pib kho. Yog tias nws yuav tsum tau noj tshuaj ua ke, kev hloov kho tshuaj ntawm ib tus neeg sawv cev hypoglycemic yuav tsum tau ob qho tib si thaum tswj hwm GCS thiab tom qab lawv tshem tawm.
- Ritodrin, salbutamol, terbutaline (kev tswj hwm hauv lub cev): beta-2 adrenergic agonists nce ntshav qabzib concentration.
Kev saib xyuas tshwj xeeb yuav tsum tau them rau qhov tseem ceeb ntawm kev tswj hwm tus kheej-glycemic. Yog tias tsim nyog, nws raug nquahu kom hloov tus neeg mob mus rau kev kho mob insulin.
3) Kev sib xyaw ua ke yuav tsum tau muab los suav
- Anticoagulants (Xws li warfarin)
Cov peev txheej ntawm sulfonylureas tuaj yeem txhim kho cov nyhuv ntawm anticoagulants thaum noj ua ke. Cov tshuaj tiv thaiv Anticoagulant yuav tsum tau kho kom haum.
COV LUS QHIA TSHWJ XEEB
Kev ntshav siab
Thaum noj sulfonylurea derivatives, suav nrog gliclazide, mob ntshav qab zib tsawg tuaj yeem tsim muaj, qee qhov mob ntawm kev mob hnyav thiab mob ntev, yuav tsum tau pw hauv tsev kho mob thiab tso dej num ntawm cov tshuaj kho kom zoo rau ob peb hnub (saib ntu "Phiv").
Cov tshuaj tuaj yeem tsuas yog kho rau cov neeg mob uas lawv noj mov tsis tu ncua thiab suav nrog pluas tshais. Nws yog ib qho tseem ceeb heev kom muaj kev noj haus nrog cov carbohydrates nrog zaub mov, txij li kev pheej hmoo ntawm kev txhim kho hypoglycemia nce nrog cov zaub mov tsis xwm yeem lossis tsis txaus, zoo li thaum noj cov zaub mov tsis zoo rau hauv carbohydrates.
Kev mob ntshav qab zib feem ntau pib txhim kho nrog cov zaub mov tsis muaj calorie ntau, tom qab ua haujlwm ntev lossis ua kom ib ce muaj zog, tom qab noj cov tshuaj ethanol uas muaj cov tshuaj pleev tshuaj, lossis thaum noj ntau yam tshuaj hypoglycemic nyob rau tib lub sijhawm.
Feem ntau, cov tsos mob ntawm hypoglycemia ploj tom qab noj mov uas muaj nplua nuj hauv carbohydrates (xws li qab zib). Nws yuav tsum tau yug hauv siab tias kev noj cov khoom qab zib tsis pab tshem tawm cov tsos mob hypoglycemic. Cov kev paub ntawm kev siv lwm cov sulfonylurea derivatives qhia tau hais tias hypoglycemia tuaj yeem rov tshwm sim dua txawm tias pib kho tus mob no. Thaum muaj cov tsos mob hypoglycemic tshaj tawm los yog lub sijhawm ntev, txawm tias muaj kev txhim kho ib ntus tom qab noj zaub mov nplua nuj hauv carbohydrates, kev kho mob xwm txheej ceev yog tsim nyog, mus txog tsev kho mob.
Txhawm rau kom zam dhau kev txhim kho hypoglycemia, kev ceev faj xaiv cov tshuaj thiab kev noj tshuaj yog qhov tsim nyog, nrog rau kev muab tus neeg mob nrog cov ntaub ntawv tiav ntawm kev kho mob.
Ib qho kev pheej hmoo ntawm hypoglycemia ntau tuaj yeem tshwm sim hauv cov xwm txheej hauv qab no:
- kev tsis kam lossis tsis muaj peev xwm ntawm tus neeg mob (tshwj xeeb yog cov neeg laus) kom ua raws li kws kho mob tau sau tseg thiab saib xyuas nws tus mob,
- Kev noj zaub mov tsis txaus thiab tsis xwm yeem, hla zaub mov noj, yoo mov thiab hloov pauv kev noj zaub mov,
- tsis txaus ntawm kev qoj ib ce thiab tus nqi ntawm carbohydrates coj,
- lub raum tsis ua hauj lwm
- daim siab ua hauj lwm hnyav
- noj tshuaj muaj yees Diabeton D MV,
- qee cov mob endocrine: mob qog, pituitary thiab adrenal tsis txaus,
- kev siv qee cov tshuaj (saib Ntu "Kev cuam tshuam nrog lwm cov tshuaj"). Cov chaw txhaj tshuaj tiv thaiv kev mob ntshav qab zib siab tuaj yeem ua npog ntsej muag thaum noj beta-blockers, clonidine, reserpine, guanethidine.
Plaws thiab lub siab ua haujlwm
Hauv cov neeg mob uas muaj mob hepatic thiab / lossis lub raum tsis ua haujlwm, cov chaw muag tshuaj thiab / lossis cov chaw muag tshuaj muaj zog ntawm gliclazide yuav hloov pauv.
Lub xeev ntawm hypoglycemia uas tsim kho hauv cov neeg mob no tuaj yeem yog lub sijhawm ntev heev, nyob rau hauv cov xwm txheej zoo li no, kev kho kom sai tsim nyog yog tsim nyog.
Tus Neeg Mob Cov Ntaub Ntawv
Nws yog ib qho tsim nyog yuav tau qhia rau tus neeg mob, nrog rau nws tsev neeg, txog qhov kev pheej hmoo ntawm kev mob ntshav qab zib, nws cov tsos mob thiab cov xwm txheej zoo rau nws txoj kev txhim kho. Yuav tsum qhia rau tus neeg mob txog cov kev pheej hmoo thiab cov txiaj ntsig zoo ntawm txoj kev kho mob uas tau thov.
Tus neeg mob xav tau qhia meej txog qhov tseem ceeb ntawm kev noj haus, kev xav kom ib ce muaj zog thiab soj ntsuam cov ntshav qabzib ntau.
Tsis muaj ntshav tswj ntshav qab zib kom tsis txaus
Glycemic tswj nyob rau hauv cov neeg mob tau txais kev kho nrog hypoglycemic cov neeg sawv cev tuaj yeem ua kom tsis muaj zog ntawm cov mob hauv qab no: kev phais mob loj thiab kev raug mob, kub hnyiab ntev, kis kab mob nrog febrile syndrome. Nrog rau cov mob no, nws kuj yuav tsim nyog los txiav kev kho mob nrog rau cov tshuaj Diabeton ® MV thiab sau tshuaj tawm kho insulin.
Hauv qee tus neeg mob, cov txiaj ntsig ntawm qhov ncauj hypoglycemic tus neeg sawv cev, suav nrog gliclazide, nyhav poob qis tom qab lub sijhawm ntev los kho. Cov nyhuv no tuaj yeem yog vim ob qho kev hloov zuj zus ntawm tus kabmob thiab txo qis hauv kev kho rau cov tshuaj. Cov nyhuv no paub tias yog kev tiv thaiv tshuaj thib ob, uas yuav tsum tau txawv ntawm thawj qhov, uas cov tshuaj tsis muab qhov xav pom kev kho mob uas twb tau muaj thaum thawj zaug teem tseg. Ua ntej kuaj pom tus neeg mob nrog cov tshuaj tiv thaiv kab mob thib ob, nws yog qhov yuav tsum tau soj ntsuam qhov tsis txaus ntawm kev xaiv koob tshuaj thiab kev ua raws li tus neeg mob lub cev noj haus.
Kev kuaj sim
Yuav kom ntsuas ntsuas glycemic tswj hwm, kev txiav txim siab tsis tu ncua ntawm cov ntshav ceev piam thaj thiab glycated hemoglobin HbA1c qib pom zoo. Ib qho ntxiv, nws raug nquahu kom ua qhov kev soj ntsuam tus kheej hauv cov ntshav cov ntshav qabzib ntau.
Sulfonylurea derivatives tuaj yeem ua rau hemolytic anemia nyob rau hauv cov neeg mob uas muaj piam thaj-6-phosphate dehydrogenase tsis txaus. Txij li thaum gliclazide yog sulfonylurea derivative, kev saib xyuas yuav tsum tau ua thaum muab tshuaj rau nws rau cov neeg mob uas muaj glucose-6-phosphate dehydrogenase tsis txaus.
Lub peev xwm ntawm kev muab tshuaj hypoglycemic ntawm lwm pab pawg yuav tsum raug txheeb xyuas.
PAUB TXOG KEV TSIS TXAUS SIAB TSAV TSHEB TSAV TSHEB THIAB LUB ROOJ SIB HAIS TXOG KEV UA HAUJ LWM YUAV TSUM TAU KEV TXAUS SIAB TSHAJ PLAWS
Cov neeg mob yuav tsum paub txog cov tsos mob ntawm lub qog ntshav qab zib thiab yuav tsum ceev faj thaum tsav tsheb lossis ua haujlwm uas yuav tsum muaj qhov siab ntawm lub cev thiab lub hlwb, tshwj xeeb tshaj yog thaum pib kho.
ISSUE FORM
30 mg hloov kho cov ntsiav tshuaj
30 ntsiav tshuaj rau ib lub hlwv (PVC / Al), 1 lossis 2 lub hlwv nrog cov lus qhia rau kev siv tshuaj kho mob hauv lub thawv ntawv thawv.
Thaum ntim khoom (ntim ntawv) ntawm Lavxias lub tuam txhab LLC Serdix: 30 ntsiav tshuaj rau ib lub ntsej muag (PVC / Al), 2 lub hlwv nrog cov lus qhia rau kev siv rau hauv thawv ntawv thawv.
COV NTAUB NTAWV CIA
Cov mob tshwj xeeb tsis tas yuav tsum muaj.
Khaws tsis ncav cuag ntawm cov menyuam yaus.
Sau B.
TXIV NEEJ LUB NEEJ
3 xyoos Tsis txhob siv tom qab hnub tas sij hawm qhia ntawm pob.
LUS NCO
Los ntawm tshuaj.
Kev tso npe rau daim ntawv pov thawj pom zoo los ntawm Servier Laboratories, Fabkis
Tsim los ntawm Servier Kev Lag Luam (Lab), Fabkis
"Lub chaw soj nstuam Servier Kev Lag Luam":
905, Txoj kev loj Saran, 45520 Gidey, Fab Kis
905, txoj kev de Saran, 45520 Gidy, Fab Kis
Txog txhua cov lus nug, tiv toj rau Lub Chaw Sawv Cev ntawm JSC "Servier Laboratory".
Sawv cev ntawm JSC "Kuaj Xyuas Ntsuas":
115054, Moscow, Paveletskaya pl. d.2, p. 3
Serdix LLC:
142150, Russia, Moscow Cheeb Tsam,
Podolsky koog tsev kawm, lub zos ntawm Sof'ino, p. 1/1
Kev tso npe rau daim ntawv pov thawj pom zoo los ntawm Servier Laboratories, Fabkis
Tsim los ntawm: Serdix LLC, Russia
Serdix LLC:
142150, Russia, Moscow Cheeb Tsam,
Podolsky koog tsev kawm, lub zos ntawm Sof'ino, p. 1/1
Txog txhua cov lus nug, tiv toj rau Lub Chaw Sawv Cev ntawm JSC "Servier Laboratory".
Sawv cev ntawm JSC "Kuaj Xyuas Ntsuas":
115054, Moscow, Paveletskaya pl. d.2, p. 3