Cov tshuaj BAGOMET - cov lus qhia, tshuaj xyuas, tus nqi thiab analogues

Bagomet txo cov piam thaj hauv cov ntshav qab zib hom 2 los ntawm kev tiv thaiv gluconeogenesis nyob rau hauv lub siab ua haujlwm, txo qis kev nqus ntawm cov piam thaj hauv txoj hnyuv thiab txhim kho nws nqus los ntawm cov leeg nqaij thiab cov nqaij rog.

Nws tsis txhawb cov hlwb hlwb los tsim cov tshuaj insulin, yog li ntawd nws tsis ua rau cov ntshav qis.

Los ntawm kev txo hyperinsulinemia, nws pab txo lub cev qhov hnyav hauv cov neeg mob rog rog ntshav qab zib. Nws muaj cov nyhuv lipolytic. Txo cov roj (cholesterol) tag nrho.

Bagomet sai thiab tag yaim hauv cov hnyuv. Nws yog sai faib tshaj cov ntaub so ntswg, tsis txuas nrog cov ntshav protein. Nws muaj peev xwm muab tso rau hauv cov ntshav liab. Nws yog tawm los ntawm lub raum, yuav luag yam tsis muaj metabolism. Nrog lub raum pathology, nws tuaj yeem tsim hauv cov nqaij hauv lub cev.

Yuav ua li cas coj BAGOMET

Cov koob tshuaj tau teeb tsa ib leeg zuj zus, coj mus rau hauv tus account glucoseemia. Thawj koob tshuaj Bagomet 500 mg yog 2-3 ntsiav tshuaj / hnub. Txhawm rau kom lub plab zom mov zoo dua, cov tshuaj txhua hnub yuav tsum tau muab faib ua 2-3 koob.

Tib qho kev muab tshuaj pib yog kho nyob rau hauv kev sib txuas nrog kev siv tshuaj insulin.

Yog tias tsim nyog, ua kom ntau dua cov tshuaj maj mam ntxiv, nrog lub sijhawm ntev txog 15 hnub. Qhov siab tshaj plaws yog 6 ntsiav tshuaj / hnub (3000 mg), muab faib ua peb koob.

Rau cov menyuam yaus txij li 10 xyoo, kev muab tshuaj thawj zaug yog 500 mg / hnub, noj thaum yav tsaus ntuj rau khoom noj. Qhov ntau tshaj kev noj tshuaj yog 2000 mg / hnub (muab faib ua 2-3 koob).

Qhov siab kawg ntawm lub caij nyoog ntev ntawm Bagomet 850 mg 3 ntsiav tshuaj / hnub, Bagomet 1000 mg 2 ntsiav tshuaj / hnub.

Ntshav Qab Zib Hom 2, nyuaj los ntawm kev rog, nrog qhov tsis muaj txiaj ntsig ntawm sulfonylurea kev npaj.

Cov Yuav Tsum Muaj

kev tiv thaiv tsis haum
lactic acidosis, ketoacidosis, precoma thiab coma
mob siab thiab mob raum tsis ua hauj lwm
kev kis mob hnyav
kev phais mob, kev raug mob (hauv qhov no insulin txoj kev kho yog qhia)
cawv intoxication
kev xeeb tub, kev pub niam mis
Kev ntsuas xoo hluav taws xob thiab xoo hluav taws xob nrog tus neeg sawv cev ntawm iodine
cov me nyuam qis dua 10 xyoo.

Cov lus piav qhia dav dav thiab cov lus qhia kom siv tshuaj Bagomet Plus

Qhov no yog cov neeg sawv cev tiag tiag ntawm cov neeg sawv cev hypoglycemic npaj rau kev tswj hwm qhov ncauj. Bagomet Plus muaj nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj zoo li lub pob, dawb nrog lub cev hauv nruab nrab. Cov khoom xyaw nquag yog metformin hydrochloride thiab glibenclamide. Nov yog lawv cov kev qhia luv luv thiab cov ntsiab cai ntawm kev nqis tes ua hauv lub cev uas raug cuam tshuam:

Thawj qhov khoom, yog koom nrog pab pawg pawg biguanide, txo qis ntshav qabzib, txo qis kev nqus ntawm carbohydrates nyob rau hauv cov zom zaub mov, cuam tshuam nrog gluconeogenesis hauv daim siab, thaum ua haujlwm rau theem ntawm tag nrho cov roj (cholesterol), LDL thiab triglycerides.
Qhov tseem ceeb thib ob yog koom nrog cov pab pawg ntawm sulfonylurea derivatives ntawm lub cim thib ob, thiab kev tswj hwm thiab kev txo qis hauv cov kua nplaum hauv cov ntshav ncig ntawm cov kab ke muab vim yog kev tsim tawm ntawm insulin secretion los ntawm pancreatic cells.

Bagomet Plus muaj cov txiaj ntsig ua rau lub cev ntawm cov kabmob ntshav qab zib, thaum nws pom tias muaj cov ntshav siab ntau ntawm cov adsorption hauv cov hnyuv. Cov tshuaj yeeb dej caw nquag dhau ntawm lawv cov siab tshaj plaws hauv cov ntshav tom qab 2-3 teev txij lub sijhawm ntawm lub qhov ncauj tswj hwm ntawm ib koob. Cov txheej txheem lwj ua rau pom lub siab, cov metabolites nquag muaj qee tawm ntawm lub raum nrog rau cov zis thiab cov kua tsib.

Kev Qhia thiab contraindications rau kev siv cov tshuaj Bagomet Plus

Cov neeg tuaj saib tam sim no ntawm cov neeg mob uas tuaj yeem kho nrog cov tshuaj Bagomet Plus yog cov neeg mob ntshav qab zib hom 2. Cov yam ntxwv ntawm tus yam ntxwv yog siv tshuaj feem ntau los ntawm kev laus, nws yog ib feem ntawm txoj kev sib koom ua ke mus rau qhov teeb meem kev noj qab haus huv lossis lwm txoj hauv kev xaiv tau nyob hauv txoj kev hloov ntshav qab zib mellitus.

Cov tshuaj Bagomet Plus muaj cov tshuaj kho mob, uas yuav tsum ua tib zoo nyeem thaum pib mus txog thaum kawg. Txwv tsis pub, cov piam thaj hauv ntshav tuaj yeem ncav cuag qhov kev txwv, thiab tus neeg mob yuav muaj mob ntshav qab zib tsis zoo thiab ntau dua. Ntawm cov kev txwv no, nws tsim nyog hais txog kev kuaj mob hauv qab no thiab kab mob ntawm lub cev:

ntshav qab zib hom 1
mob siab los yog mob raum,
qog ntshav,
porphyria
lactic acidosis,
haus cawv ntev,
mob ua ntej kev phais mob
rov mob rau theem kab mob
lub hnub nyoog so haujlwm
cev xeeb tub, lub sijhawm pub niam mis.

Tsis tas li ntawd, nws yog ib qho tseem ceeb kom nco ntsoov txog kev sib cuam tshuam yeeb tshuaj, piv txwv li, siv cov tshuaj miconazole uas muaj qhov tsis sib haum xeeb. Cov kev txwv no siv rau cov neeg mob uas lub siab tsis tshua zoo ntxiv rau cov khoom xyaw nquag hauv Bagomet Plus. Txwv tsis pub, muaj qhov ua xua tawm pob, ua xua, khaus, tawm pob ntawm daim tawv nqaij. Daim ntawv ntawm qhov hu ua "teebmeem tshwj xeeb" los ntawm kev kho mob tsis xaus rau ntawd.

Qhov tshwm sim thiab tshwm sim ntawm kev haus dej ntau dhau nrog Bagomet Plus

Tsis yog txhua tus neeg mob tsim nyog rau kev teem caij, qee leej yuav tsum yeem tsis lees txais kev kho mus ntxiv vim qhov tshwm sim. Ntau zaus nws yog xeev siab, ntuav, mob plab, smack "npib tooj liab" hauv qhov ncauj, erythema thiab ntshav liab. Kev kho ntawm cov tshuaj txhua hnub tsis ua rau muaj qhov hloov zoo, yog li ntawd, thaum cov kev mob tshwm sim, cov tshuaj tau qhia tias yuav hloov.

Nrog kev muaj txheej txheem ntawm kev tsis sib haum xeeb ntawm txhua hnub ntawm Bagomet Plus, lactate acidosis tshwm sim hauv tus neeg mob lub cev nrog ntshav qab zib mellitus, hemodialysis yog qhia txog kev tshem tawm. Qhov thib ob tsis muaj kev phom sij txaus ntshai ntau tshaj ntawm kev haus ib ce ntau dhau ntawm cov tshuaj yog qhov tsos ntawm cov tsos mob ntawm lub qog ntshav qab zib. Cov no yog kev mob taub hau thiab kev tshaib kev nqhis heev, tawm hws ntau dhau, lub plawv dhia tsis txaus, ntshai tsam ntshai, tswj tsis tau lub cev, pw tsis tsaug zog, tsis muaj zog, kiv taub hau, mob puas hlwb ib ntus, thiab tsis hnov rhiab. Rau kev kho mob kom vam meej, tus neeg mob tau qhia txog kev siv iv 40% kev daws teeb meem ntawm dextrose lossis glucagon iv, i / m, s / c.

Kev noj tshuaj txhua hnub, kev siv cov tshuaj Bagomet Plus

Cov ntsiav tshuaj yuav tsum tau noj ntawm qhov ncauj, thaum noj mov, thaum haus dej ntau. Cov koob tshuaj yog txiav txim siab ntawm tus kheej tom qab dhau ntau txoj kev kuaj sim, saib xyuas cov ntshav qab zib. Qhov nruab nrab koob tshuaj yog 1 ntsiav tshuaj ib hnub ib zaug, lub sijhawm siv tshuaj kho ntau dua yog 1-2 lub lis piam. Tom qab ntawd kho nrog Bagomet Plus txuas ntxiv, tab sis nrog tus neeg kho ntawm cov tshuaj txhua hnub. Qhov siab tshaj plaws tau tso cai rau txhua hnub koob ntawm Bagomet Plus yog 4 ntsiav tshuaj, thiab nws ntau dhau qhov teeb meem kev siv ntau tshaj.

Cov tshuaj ntawm cov tshuaj Bagomet Plus

Yog tias cov tshuaj tsis haum, lossis muaj kev sib cuam tshuam tshuaj, cov kws kho mob pom zoo kom hloov txoj cai hloov. Muaj kev sib piv, tab sis kev soj ntsuam tag nrho yog yuav tsum paub ua ntej kom paub meej cov kev siv tshuaj txhua hnub thiab txo qis kev pheej hmoo ntawm kev mob tshwm sim. Cov kws kho mob tshwj xeeb hauv txoj hauv kev taw qhia xav kom them sai sai rau cov tshuaj hauv qab no:

Kev txheeb xyuas txog Bagomet Plus

Cov neeg mob ntshav qab zib feem ntau hais txog cov tshuaj yam ntxwv ntawm kev sib tham hauv online kho mob. Lawv tshaj tawm tias Bagomet Plus tiv thaiv cov ntshav qab zib hom 2 yog cov tshuaj zoo uas tau pom qhov txawv los ntawm nws cov txiaj ntsig xaiv. Hauv qhov no, peb tab tom hais txog lub sijhawm ntawm kev hloov kho ntawm cov yam muaj sia nyob hauv lub cev. Yog tias muaj kev phiv thiab cov kev mob tshwm sim tsis tshwm sim tam sim ntawd, qhov tshwm sim ntawm kev kho mob yuav yog. Txwv tsis pub, tsis muaj teeb meem kev noj qab haus huv, thiab yuav tsum hloov chaw. Yog li kev tshuaj xyuas ntawm tus mob ntshav qab zib tau muab faib ua ob pawg: qee qhov cem cem Bagomet Plus, lwm tus qhuas.

Nws yog tsim nyog sau cia cais tias muaj kev pheej hmoo ntawm phiv los ntawm Bagomet Plus, thiab ntau tus neeg mob tau ntsib nrog qhov tsis sib xws. Lawv sau ntawv tias lawv hloov cov tshuaj sai, vim hais tias qhov xwm txheej zoo li qub tau zoo zuj zus lawm. Yog li Bagomet Plus yuav tsum tsis yog tshwm sim los ntawm kev noj tshuaj ntawm tus kheej, txwv tsis pub dhia hauv cov ntshav qab zib tau muab.

Lub ntsiab contraindications, phiv tshuaj tiv thaiv ntawm lub cev

Cov tshuaj tsis tuaj yeem raug sau rau hom 1 mob ntshav qab zib mellitus, kab mob ntshav qab zib poj koob yawm txwv, coma, mob ntshav qab zib ketoacidosis, mob raum thiab mob ntshav siab tsis txaus, lactic acidosis, mob ntshav qab zib kom qaug. Bagomet kuj tseem tsis pom zoo rau cov mob voos xwm txheej uas yuav tsum tau qhia txog cov tshuaj iodine uas muaj cov kab mob sib xyaw.

Cov kev daws yog contraindicated nyob rau hauv ntev thiab mob mob, uas nrog cov pa oxygen tshaib plab, uas yog: lub xeev poob siab, myocardial infarction, lub cev qhuav dej. Nws kuj tseem muaj kev txwv rau kev siv cov tshuaj rau porphyria, concomitant siv nrog Miconazole, cev xeeb tub, thiab pub niam mis.

Nws ua tau tias thaum kho tus neeg mob ntshav qab zib yuav muaj qhov tsis txaus lub cev: tawm tsam ntuav, xeev siab, mob plab, poob qab los noj mov, saj ntawm hlau hauv qhov ncauj, thiab erythema. Metformin nyob rau hauv cov tshuaj muaj pes tsawg leeg qee zaum provokes ib tug txo nyob rau hauv nqus, lactate acidosis.

Lwm qhov sib xyaw ntawm cov tshuaj Bagomet - Glibenclamide - muaj peev xwm ua rau muaj tej yam kev mob zoo li no:

tawv nqaij ua pob, khaus, urticaria,
ntuav, xeev siab, mob plab,
ntev li ntawm kev ua haujlwm ntawm hepatic transaminases,
leukopenia, mob ntshav qab zib hemolytic, thrombocytopenia.

Tej zaum muaj qhov nce ntawm urea hauv cov ntshav, pob txha pob txha aplasia, pancytopenia, hyponatremia, disulfiram-zoo li cov tshuaj tiv thaiv.

Pharmacological cov yam ntxwv ntawm Bagomet

Bagomet yog ib qho tshuaj hypoglycemic uas ua rau ob qho tib si sai ntawm cov piam thaj thiab qhov ua tau zoo tom qab noj mov. Cov tshuaj tsis cuam tshuam rau kev tsim ntawm cov tshuaj insulin. Ntawm cov kev mob tshwm sim ntawm cov neeg mob ntshav qab zib tsis yog kho. Kev muaj peev xwm kho tau tshwm sim tom qab inhibition ntawm glycogenolysis thiab gluconeogenesis, provoking inhibition of glycogen hauv daim siab.

Bagomet txhim kho qhov ua tau zoo ntawm cov enzyme uas ua kom nrawm dua ntawm cov khoom sib xyaw ntawm glycogen, ua rau muaj peev xwm thauj tau ntau dua ntawm cov khoom siv membrane ntawm cov kua nplaum. Cov tshuaj kho cov lipid metabolism - nrog hom 2 ntshav qab zib muaj txoj hmoo ua kom poob phaus.

Bagomet muab piv nrog lub peev xwm sib xyaw kom zoo thiab qhov kev zom sai.

Thaum noj, cov tshuaj tam sim ntawd nqus los ntawm lub plab zom mov, qhov siab tshaj plaws tau mus txog hauv ob thiab ib nrab teev. Ua rau kom qis li qhov ua tau ntawm cov tshuaj txuam thaum tau txais zaub mov. Bagomet cov kev ntsuas kev nyab xeeb yog mus txog 60% ntawm tag nrho cov tshuaj ntawm cov tshuaj xa mus rau cov kabmob.

Raws li cov txiaj ntsig ntawm kev tshawb fawb pharmacokinetic, peb tuaj yeem xaus tias cov tshuaj sai sai rau ntawm cov ntaub so ntswg, ua kom muaj hauv plasma. Cheebtsam ntawm cov tshuaj tsis khi rau cov protein, nws tuaj yeem nkag mus rau hauv cov ntshav liab, tab sis hauv cov ntshav lawv muaj tsawg dua piv rau ntshav.

Cov kev sim tau paub tseeb tias cov tshuaj tsis tau metabolized hauv lub cev - lub raum nws zoo nws nyob hauv nws lub xeev qub. Hauv qhov no, ib nrab-lub neej yog rau thiab ib nrab hnub teev. Bagomet tawm tawm yog qhov kev xav los ntawm kev ua haujlwm siab glomerular pom thiab lub raum plab tsis pom kev, yog li ntawd, txhua tus neeg mob nrog lub raum pathologies yog qhov muaj kev pheej hmoo.

Ib nrab-lub neej tau nce, uas txhais tau tias muaj kev pheej hmoo ntawm kev txuam nrog tshuaj.

Kev ntsuas qhov tseeb thiab txoj kev siv

Bagomet yog npaj rau kev kho mob rau cov neeg mob ntshav qab zib nrog insulin-ywj siab hom kab mob thiab kev rog (hauv qhov tsis muaj ketoacidosis thiab kev tsis txaus teb rau kev kho mob nrog sulfonylureas).

Cov tshuaj yog npaj rau kev siv sab hauv. Nqos cov ntsiav tshuaj kom tag nrho nrog dej. Qhov no feem ntau tshwm sim nrog cov zaub mov lossis tam sim ntawd tom qab nws. Kev muab tshuaj thawj zaug yog 500-100 mg / hnub, nyob ntawm qib glycemia. Koj tuaj yeem hloov kho tsuas yog tom qab ob lub lim tiam ntawm kev nquag thiab kev saib xyuas ntawm glycemic ntsuas.

Yog tias tus kws kho mob tsis tau txiav txim siab txog tus neeg mob txog tus neeg mob, tom qab ntawd tus qauv muab tshuaj kho tau yog li ntawm 1500 txog 2000 mg. Nws yog tsis yooj yim sua kom dhau qhov siab tshaj plaws kev coj ua. Yog tias cov tshuaj provokes kev quav ntawm cov quav, koj tuaj yeem tsoo qhov kev cai niaj hnub los ntawm 2-3 zaug.

Nrog cov kev kho mob nyuaj "Bagomet ntxiv rau cov tshuaj insulin npaj", cov qauv tshuaj yog 1500 mg / hnub. Rau cov ntsiav tshuaj nrog lub peev xwm ncua ntev, qhov qib siab zoo rau txhua hnub yog 850 mg -1000 mg. Nrog kev muaj peev xwm tiv taus ib txwm, lawv nres ntawm kev saib xyuas ntawm 1700 mg / hnub., Txwv - 2550 mg / hnub. Nrog txoj kev kho mob nyuaj nrog lwm cov tshuaj rau cov ntshav qab zib, ib ntsiav tshuaj (850 mg lossis 100 mg) yog tshuaj.

Hauv kev laus, Bagomet noj tsis ntau tshaj 1000 mg / hnub. Koj tuaj yeem muab tshuaj rau cov menyuam yaus hnub nyoog 10 xyoo. Cov menyuam yaus, nrog rau cov laus, yuav tsum pib ib chav kho mob nrog 500-850 mg / hnub. Hauv cov menyuam yaus, qhov tshuaj ntau tshaj txhua hnub yog 2000 mg.

Qhia Txog Tshuaj Yeeb

Bagomet's hypoglycemic muaj peev xwm txhim kho los ntawm sulfanilamides, insulin, acarbose, tshuaj tsis-steroidal anti-inflammatory tshuaj, ACE thiab MAO inhibitors, oxytetracycline, β-blockers.

Glucocorticosteroids, GOK, epinephrine, glucagon, cov tshuaj tiv thaiv qog tshuaj, cov tshuaj sympathomimetics, thiazide thiab "voj" diuretics, phenothiazine thiab nicotinic acid derivatives inhibit nws txoj haujlwm.

Qhov kev tshem tawm ntawm Bagomet los ntawm cov plab hnyuv siab raum yog tiv thaiv los ntawm cimetidine. Anticoagulant muaj peev xwm ntawm Coumarin derivatives inhibits Bagomet.

Qhov ua tau zoo tshaj plaws ntawm kev ntxuav lub cev ntawm co toxins yog hemodialysis. Raws li kev qhia, nws yog ntxiv los ntawm kev kho mob.

Tshaj tsos mob

Yog hais tias cov koob tshuaj ntawm Bagomet yog saum toj no cov kev tso cai ntau tshaj plaws, cov kab mob lactic acidosis nrog rau qhov tshwm sim loj tshaj plaws hauv daim ntawv ntawm kev tsis nco qab thiab txawm tuag taus yog ua tau. Cov txiaj ntsig zoo sib xws yog tshwm sim los ntawm kev nce siab ntawm cov tshuaj hauv lub cev muaj teeb meem nrog nws cov zis tawm los ntawm lub raum. Qhov teeb meem loj tuaj hauv ob peb teev thiab xa nrog cov yam ntxwv ntawm tus yam ntxwv:

Dyspeptic mob
Kev Ntshav Qab Zib,
Ua txhaum ntawm cov lus sib dhos ntawm lub plab hnyuv,
Mob hauv plab
Neej Hmoob
Plam kev sib koom tes
Tsaus muag thiab mob plab tso dag.

Yog tias tsawg kawg ib feem ntawm cov tsos mob tau tshwm sim, Bagomet yuav tsum tau kho kom sai, thiab tus neeg raug mob yuav tsum tau mus pw hauv tsev kho mob.

Tso tawm daim ntawv, muaj pes tsawg leeg, chaw cia khoom

Cov ntsiav tshuaj tuaj yeem muaj cov duab thiab xim sib txawv, nyob ntawm qhov ntau npaum li cas: dawb, puag ncig thiab convex - 500 mg txhua qhov, nyob rau hauv daim ntawv ntawm cov tshuaj ntsiav 850 mg bluish hauv xim thiab 1000 mg hauv dawb. Cov yav tas muaj lub zog ntev. Qhov tshwj xeeb ntawm daim ntawv tso tawm yog cov kab sib faib thiab cov chaw tsim khoom lub logo, embossed ntawm txhua cov ntsiav tshuaj.

Ib ntsiav tshuaj muaj los ntawm 500 txog 100 mg ntawm cov tshuaj ua kom nquag plias metformin hydrochloride ntxiv rau cov neeg tsis paub nyob rau hauv daim ntawv ntawm croscarmellose sodium, povidone, stearic acid, pob kws hmoov txhuv, lactose monohydrate.

Cov khoom siv xub ntiag nrog cov tshuaj yuav tsum tau muab tso rau hauv qhov chaw uas cov menyuam yaus nkag tsis tau, txog rau qhov kub txog 25 ° C. Khaws Bagomet tsis pub dhau ob xyoos.

Cov lus ua piv txwv thiab analogues tshuaj

Bagomet synonyms suav nrog cov tshuaj uas ob pawg (tshuaj tiv thaiv kab mob hauv qhov ncauj) thiab cov nquag ua ke (metformin) coincide.

Bagomet's analogs yog cov tshuaj nyob rau hauv uas tsawg kawg ib tus kab mob lossis kev mob sib txig sib luag hauv cov lus tim khawv, nyob rau hauv rooj plaub no hom 2 ntshav qab zib.

Av ‡ Q
Apidra
Baeta
Glemaz
Glidiab
Glucobay,
Ntujnrim,
Lymphomyozot,
Levemir Penfill,
Levemir Flekspen,
Multisorb,
Methamine
NovoFormin,
Pioglar
Txog rau cov,
Rau menyuam yaus.

Nrog cov kev kho mob nyuaj nrog lwm cov tshuaj ntawm cov txiaj ntsig zoo sib xws, nws yog ib qho tseem ceeb uas yuav tsum xav txog qhov muaj peev xwm txo tus mob ntshav qab zib tsawg.Cov tshuaj muaj peev xwm ua kom muaj kev cuam tshuam kev sib koom tes thiab txo cov tshuaj psychomotor qeeb, yog li thaum ua haujlwm nrog cov txheej txheem lossis thaum tsav tsheb, nws zoo dua rau qhov tsis kam noj tshuaj. Kev siv Bagomet koom nrog txoj cai yuav tsum tau ua raws nrog cov zaub mov muaj carb tsawg uas tswj kev noj cov carbohydrates hauv cov ntshav.

Kev txheeb xyuas txog Bagomet

Txog ntawm cov tshuaj Bagomet, kev tshuaj xyuas ntawm kws kho mob feem ntau yog qhov zoo. Raws li cov kws tshaj lij, kev noj tshuaj xws li cov tshuaj yeeb tshuaj no muaj peev xwm tswj cov ntshav qab zib nyob ntev li 12 teev. Cov sijhawm zoo no lav nws qee yam zoo: koj tuaj yeem txo qhov tsawg zaus ntawm kev noj tshuaj, txhim kho kev soj ntsuam ntawm cov txheej txheem hauv metabolic. Tib lub sijhawm, kev nqus ntawm cov khoom ua kom nquag plias los ntawm kev zom zaub mov tau zoo tuaj thiab txoj kev pheej hmoo ntawm kev tsim cov kev mob tshwm sim yog tsawg.

Cov lus piav qhia txog cov tshuaj tsis tuaj yeem ua ib daim ntawv qhia rau kev siv. Ua ntej yuav khoom, koj yuav tsum tau sab laj nrog cov kws kho mob endocrinologist, thiab ua ntej noj tshuaj Bagomet, nyeem cov lus qhia rau kev siv los ntawm cov khw. Cov ntaub ntawv hais txog Bagomet yog muab rau kev paub dav dav nrog nws lub peev xwm thiab tsis yog kev qhia rau kev kho tus kheej. Kev noj tshuaj zoo rau tus kab mob ntshav qab zib, suav txog qhov mob ntshav qab zib, mob ntshav qab zib thiab cov kab mob kev noj qab haus huv ntawm cov ntshav qab zib, tsuas yog tsim los ntawm tus kws tshwj xeeb.

Kev ntsuas rau siv

Tshuaj Bagomet Ntxiv siv rau ntshav qab zib hom 2 rau cov neeg laus:
- raws li cov tshuaj thib ob nrog kev ua tsis zoo ntawm kev kho kev noj haus, kev tawm dag zog thiab kev kho mob yav dhau los nrog metformin lossis glibencl amide,
- los hloov cov kev kho mob yav dhau los nrog ob yam tshuaj (metformin thiab glibenclamide) hauv cov neeg mob uas muaj lub qog thiab tswj tau zoo ntawm glycemia.

Txoj kev ntawm daim ntawv thov

Yog tias tsim nyog, txhua 1-2 lub lis piam tom qab pib kho, qhov tshuaj ntawm lub tshuaj kho raws li theem ntawm cov piam thaj hauv cov ntshav.
Thaum hloov cov kev sib xyaw ua ke dhau los nrog metformin thiab glybeklamide, 1-2 ntsiav tshuaj Bagomet Ntxiv 500 mg / 2.5 mg lossis 500 mg / 5 mg (nyob ntawm qhov koob tshuaj dhau los) raug xaj 2 zaug hauv ib hnub - sawv ntxov thiab yav tsaus ntuj.
Qhov siab tshaj plaws txhua hnub yog 4 ntsiav tshuaj ntawm cov tshuaj (500 mg / 2.5 mg lossis 500 mg / 5 mg, uas yog 2000 mg metformin / 20 mg glibenclamide) Cov ntsiav tshuaj yuav tsum tau noj nrog zaub mov noj.

Sab sij huam

Cov tshuaj Metformin-cuam tshuam: xeev siab, ntuav, mob plab, tsis qab los noj mov yog cov tsos mob tshwm sim thaum pib kho thiab feem ntau yuav ploj mus lawv tus kheej thiab tsis tas kho tshwj xeeb.
Txhawm rau tiv thaiv kev txhim kho ntawm cov tsos mob no, nws raug nquahu kom noj cov tshuaj nyob rau hauv 2 koob tshuaj, qhov nce qeeb ntawm lub koob tshuaj kuj tseem txhim kho nws txoj kev kam rau siab, "nws yog xim hlau" saj hauv lub qhov ncauj, erythema, megaloblastic anemia, lactic acidosis.
Vim lub ntsej muag glibenclamide: ua rau lub cev tsis muaj ntshav qab zib, mob ntshav qab zib tsis tsaug zog (yog hais tias lub koob tshuaj no tau ua txhaum thiab noj tsis txaus), daim tawv nqaij ua xua: urticaria, tawm pob, khaus, ua kom lub cev tsis haum, nyob rau qee kis, mob nyhav rau cov tawv nqaij ua pob, ua npaws, arthralrhea, tom qab ntawd ntuav, mob nyob rau hauv thaj chaw epigastric, muaj kev ua si ntau ntawm "daim siab" enzymes, cholestatic jaundice, leukopenia, thrombocytopenia, tsis tshua muaj - agranulocytosis, hemolytic anemia, pancytopenia, "antab cov nyhuv meej "thaum haus cawv.

Cev xeeb tub

Thaum kho nrog tshuaj Bagomet Ntxiv nws yog ib qho tsim nyog yuav tsum tau qhia rau tus kws kho mob txog qhov kev npaj cev xeeb tub thiab qhov pib ntawm kev xeeb tub. Thaum npaj kev xeeb tub, nrog rau kev muaj menyuam hauv plab thaum lub sijhawm noj Bagomet Plus, cov tshuaj yuav tsum tso tseg thiab tshuaj insulin kho mob.
Bagomet Plus yog sib kis hauv kev pub niam mis, vim tias tsis muaj ib qho pov thawj ntawm nws qhov peev xwm mus rau hauv niam cov kua mis.

Tso tawm daim ntawv, muaj pes tsawg leeg thiab ntim khoom

Cov tshuaj no muaj nyob hauv daim foos. Txhua chav nyob muaj biconvex, oval duab, nrog cov xeeb ceem ntawm "1000" ntawm ob sab. Nws yog them nrog lub plhaw glossy ntawm cov xim dawb. Cov tshuaj ua haujlwm nquag yog metformin hydrochloride hauv kev siv tshuaj ntau npaum li 500, 850 mg thiab 1 g. Magnesium stearate thiab povidone yog cov khoom siv ntxiv. Txuam cov cheebtsam - macrogol 8000 thiab 400, huv opadra.

INN cov chaw tsim khoom

Lub npe thoob ntiaj teb nonproprietary (INN) ntawm cov tshuaj yog metformin. Tus tsim kev lag luam tshwj xeeb yog tshuaj lag luam rau Fabkis Merck Sante. Tseem muaj ib daim ntawv teev cov yeeb yaj kiab txawv teb ntawm cov yeeb tshuaj, cov tshuaj sib txuam ntawm uas yog metformin: Bagomet (Argentina), Avandamet (Spain), Bagomet ntxiv (Argentina), Amaril M (Republic of Korea). Kev lag luam kws tshuaj hauv Lavxias kuj tsim cov khoom lag luam zoo sib xws. Cov no yog Metglib, Glimecomb, Metformin Richter, Gliformin Prolong thiab Gliformin.

Tus nqi ntim ntawm cov tshuaj qub hauv Lavxias yog nyob ntawm qhov ntau npaum li cas ntawm cov tshuaj nquag thiab tus naj npawb ntawm cov ntsiav tshuaj. Ib pob ntawm 1000 mg (30 pcs.) Qhov nruab nrab yog muag rau 350 rubles., 60 pcs. - 680 RUB. 30 units ntawm 850 mg yog kwv yees li 320 rubles. Ib pob ntawm 500 mg rau 30 pcs. raug nqi txog 270 rubles., rau 60 - 420 rubles. Tus nqi ntawm ib cov tshuaj yuav sib txawv raws li thaj av ntawd, nrog rau txoj cai them tus nqi ntawm cov khw muag tshuaj.

Cov Tshuaj Pharmacokinetics

Cov tshuaj ua kom yoog mus tag rau hauv lub lumen ntawm lub plab zom zaub mov. Thaum noj nrog zaub mov, txoj kev no maj mam poob. Lub bioavailability ntawm cov tshuaj yog hais txog 60%. Qhov siab tshaj plaws yog pom tom qab 2.5 teev

Qhov muaj feem tseem ceeb hauv lub sijhawm luv luv tau muab faib thoob plaws lub cev thiab xyaum tsis cuam tshuam nrog cov ntshav ntshav protein. Glucophage metabolism yog tsuas yog paub nyob rau hauv lub raum cov ntaub so ntswg. Ib nrab-lub neej yog 6,5 teev. Hauv cov neeg mob uas lub raum tsis ua haujlwm, qhov nruab nrab ntawm lub sijhawm no nce ntxiv ntawm 1.5-2 zaug. Hauv qhov no, ib qho kev xav ua ntej rau kev tsub zuj zuj ntawm cov tshuaj nquag hauv lub cev yog yuav zoo.

Qhov tseem ceeb yog insulin-foos daim foos, nrog rau kev rog nrog cov tsis muaj peev xwm ua lub cev thiab ua kom lub cev yuag. Raws li ib daim ntawv teev nqaim ntawm kev qhia rau cov kab mob glucophage, hauv qab no yog qhov txawv:

Kev kho kab mob ntshav qab zib hauv cov neeg mob hnub nyoog 10 xyoo. Qee qhov xwm txheej, yuav siv tau nrog kev siv tshuaj insulin.
Kev kho mob ntawm 2 daim ntawv ntawm pathology rau cov laus ua ke nrog cov tshuaj insulin lossis lwm tus neeg mob hypoglycemic. Tsawg tsawg zaus, cov tshuaj siv rau kev kho mob monotherapy.

Glucophage yog pom zoo rau kev tiv thaiv mob ntshav qab zib hom 2.

Cov lus qhia rau kev siv (ntau npaum)

Rau kev kho mob ntshav qab zib hauv cov neeg laus cov neeg mob ua ib feem ntawm mono - lossis kev sib xyaw ua ke, cov tshuaj siv tau raws li cov qauv hauv qab no:

kev siv tshuaj thawj zaug (850, 500 mg) yog 2-3 zaug hauv ib hnub, thaum lossis tom qab noj mov,
qhov hloov kho tau tsim nyob rau txhua txhua 2 lub lis piam raws li cov txiaj ntsig ntawm cov piam thaj hauv ntshav. Kev nce ntxiv hauv kev muaj tshuaj ntau ntau txo cov kev pheej hmoo ntawm cov tshuaj tiv thaiv tsis zoo ntawm txoj hnyuv plab,
Tus qauv kev tswj tus nqi yog 1,500-2,000 mg rau ib hnub. Txhawm rau kom txo qhov tsis xav ua rau lub plab zom mov, daim duab no tau muab faib rau 2-3 koob tshuaj. Qhov siab tshaj plaws tau tso cai rau noj txhua hnub tsis yog ntau dua 3000 mg,
cov neeg mob yuam kom noj txog 3000 mg ib hnub twg yuav tsum pauv mus rau metformin ntawm qhov ntau npaum ntawm 1000 mg,
Txhawm rau kom tau txais qhov siab tshaj plaws kho nyob rau hauv kev kho mob ntawm kev siv tshuaj insulin, kev sib xyaw ntawm cov tshuaj no thiab Glucofage siv. Qhov muab tshuaj thawj zaug yog 850 lossis 500 mg 2-3 zaug ib hnub. Hauv qhov no, cov tshuaj insulin raug xaiv ib tus zuj zus.

Hauv cov menyuam yaus hnub nyoog 10 xyoo thiab ntau dua, nws raug siv los ntawm kev sib xyaw lossis tshuaj pleev ib ce. Rau cov neeg mob uas yau dua, kev noj tshuaj thawj zaug yog 850 lossis 500 mg ib hnub ib zaug. Qhov pib txij li niaj hnub los kho cov me nyuam yog 2000 mg. Nws tau muab faib ua ob peb txoj hauv kev.

Cov neeg uas mob ntshav qab zib yog pom tias noj tshuaj ntau dua txhua hnub ntawm 1000 txog 1700 mg, uas tau pom zoo kom muab faib ua 2 koob tshuaj thiab noj nrog zaub mov. Rau cov neeg mob uas tau hais tias mob raum tsis ua haujlwm, Glucophage yog kho tsuas yog tsis muaj kev pheej hmoo ntawm mob lactic acidosis. Qhov pib ntsuas kev noj tshuaj txhua hnub hauv qhov no yog 1 g (1000 mg). Thaum kho, nws yog qhov yuav tsum tau saib xyuas lub raum ua haujlwm kom tsis tu ncua. Nrog ib qho kev txo qis ntawm creatinine tshem tawm mus rau 45 ml / min thiab qis dua, tswj hwm ntawm Glucofage yog txwv tsis pub.

Rau cov neeg laus, cov koob tshuaj yog xaiv ib tus zuj zus raws li ntsuas ntawm lub raum ua haujlwm.

Noj ntau dhau

Ib qho kev poob qis hauv kev saib xyuas ntawm cov piam thaj hauv cov ntshav tsis tau pom dua txawm tias muaj qhov nce ntxiv ntawm cov tshuaj txhua hnub los ntawm 42 zaug. Dua li ntawm qhov no, cov neeg mob uas siab tshaj qhov kev tso cai ntau tshaj plaws ua rau muaj kev pheej hmoo ntawm cov kab mob lactic acidosis. Nrog rau kev txhim kho tus mob no, nws raug nquahu kom tsum tsis txhob siv cov tshuaj metformin tam sim ntawd. Cov neeg mob zoo li no yuav tsum tau txais kev kho mob sai, ua raws li kev txiav txim siab txog kev saib xyuas ntawm lactate hauv cov ntshav. Txoj kev kho mob zoo tshaj plaws rau cov mob lactic acidosis yog hemodialysis.

Yeeb tshuaj sib cuam tshuam

Cov kws kho mob pom zoo kom ceev faj thaum siv cov tshuaj no hauv kev sib xyaw nrog cov tshuaj hauv qab no:

Kev tshuaj ntsuab. Tej zaum yuav ua rau kev loj hlob ntawm lub raum tsis ua haujlwm thiab lactic acidosis.
Glucocorticosteroids. Qhov ntxim nyiam ntawm ketosis.
Txhaj tshuaj beta-2-adrenergic agonists. Lawv muaj peev xwm nce cov piam thaj hauv ntshav plasma.

Nws tsis pom zoo rau kev sib xyaw ntawm kev siv Glucofage thiab ethyl cawv. Xws li qhov sib xyaw no yuav ua rau tsis yog mob lom, tab sis kuj tseem muaj qhov siab ntawm qhov tshwm sim rau kev txhim kho ntawm cov kab mob lactic acidosis. Kev siv txoom ib txhij ntawm metformin thiab iodine-based radiopaque tshuaj yog txwv tsis pub muaj. Hauv qhov no, qhov pheej hmoo ntawm cov kab mob lactic acidosis nce.

Cawv tau zoo

Muab lub hauv paus ntsiab lus ntawm kev ua ntawm cov tshuaj no, nws tuaj yeem sib cav tias nws cov kev sib xyaw ua ke nrog kev haus cawv nrog cov dej cawv tuaj yeem ua rau muaj kev haus dej cawv ntau ua rau qaug cawv thiab lactic acidosis. Qhov no yog qhov tseeb tshwj xeeb tshaj yog rau cov neeg mob uas raug mob los ntawm kev ua haujlwm tsis txaus siab, nrog rau cov neeg uas tau yuam kom cov zaub mov tsis muaj calorie tsawg. Thaum lub sijhawm kho nrog metformin kev npaj, nws yog ib qho tsim nyog yuav tsum tsis txhob siv txawm tias muaj cawv tsawg, nrog rau kev siv tshuaj yaj yeeb. Yog tias lawv tau noj tib lub sijhawm, ib tus neeg xav tau kev kho mob sai sai.

Cov lus qhia tshwj xeeb

Ua ntej pib kho mob ntshav qab zib rau cov hluas thiab menyuam yaus, nws yog ib qho tseem ceeb kom ntseeg tau tias muaj kev kuaj mob tsim nyog. Thaum kuaj mob hauv tsev kho mob, nws tau ua pov thawj tias kev siv cov piam thaj tsis muaj kev cuam tshuam ntawm kev pub dawb thiab kev loj hlob ntawm lub cev tag nrho. Cov neeg mob uas tau mob plawv tsis ua haujlwm, nws raug nquahu kom soj ntsuam qhov kev ua haujlwm hauv lub siab thaum kho nrog metformin. Tsis tas li ntawd, nws raug nquahu tias creatinine tshem tawm kev txheeb xyuas ua ntej pib kho nrog tshuaj. Yog tias tus neeg muaj kev npaj phais mob, ces qhov txais tos ntawm Glucophage nres 2 hnub ua ntej kev phais mob.

Siv rau thaum yau

Kev siv cov glucophage rau kev kho mob ntshav qab zib tsuas yog siv tau txij li 10 xyoo. Hauv cov neeg mob zoo li no, cov tshuaj siv ob qho tib si nrog kev siv tshuaj insulin thiab kev ywj siab ntawm nws tus kheej. Lub ntsiab lus tseem ceeb hauv kev kho mob ntawm cov menyuam yaus yog nruj rau kev haus ntau npaum li cas. Yog hais tias tus me nyuam nyias muaj nyias contraindications, ces tsuas yog muaj cov tshuaj insulin nkaus xwb. Thawj koob tshuaj txhua hnub rau kev kho mob ntawm cov neeg mob laus dua 10 xyoo yog 850 lossis 500 mg. Nyob rau hauv lub neej yav tom ntej, nws tau nce rau 2000 mg, noj ntau zaug hauv ib hnub.

Txais tos thaum laus

Kev siv cov tshuaj no rau kev kho mob ntshav qab zib hom 2 hauv cov neeg mob hnub nyoog ntau dua 60 xyoo yog qhov ua tsis tau. Cov kev txwv no cuam tshuam nrog qhov kev pheej hmoo siab ntawm kev mob raum tsis ua haujlwm nyob hauv cov neeg mob no. Yog tias nws tsis tuaj yeem txwv tsis pub noj tshuaj, nws txoj kev noj tshuaj raug pom zoo kom xaiv los xaiv tus kheej. Tsis tas li ntawd, cov neeg laus raug saib xyuas tsis tu ncua tau cov tshuaj muaj nuj nqi (tsawg kawg 3 zaug hauv ib xyoos). Nrog rau qhov txo qis hauv qhov ntsuas no, kev kho mob nrog Glucofage tau txiav tawm tam sim ntawd.

Cov lus thiab cov xwm txheej ntawm kev cia

Nws raug nquahu kom nyob hauv qhov chaw tsaus ntawm qhov kub tsis tshaj + 25º C, tsis suav menyuam yaus nkag mus rau nws. Lub txee lub neej ntawm cov ntsiav tshuaj hauv qhov ntau npaum ntawm 1000 mg tsis yog ntau dua 3 xyoos, 850 thiab 500 mg - 5 xyoos. Nws yog txwv tsis pub siv cov tshuaj tom qab lub sijhawm lav. Qhov no tuaj yeem ua rau lub cev tsis huv hauv lub cev thiab ua rau muaj ntau cov kev mob tshwm sim, mus txog thaum muaj xwm ceev.

Piv nrog tshuaj zoo sib xws

Kev lag luam kws tshuaj ua ntau cov qauv txheej txheem ntawm Glucophage, uas tsis tsuas yog muaj cov txiaj ntsig kho kom zoo sib xws, tab sis kuj tseem muaj tus lej ntawm cov yam ntxwv sib txawv. Daim ntawv teev cov npe nrov tshaj plaws muaj xws li:

Siofor. Metformin hauv ib qhov tau tshuaj ntau npaum 500 mg. Muaj cov ncauj lus ntau ntxiv ntawm cov ntu ntu pabcuam ntxiv. Lwm qhov tsis zoo yog lub sijhawm luv luv ntawm kev kho mob (txog li ib nrab ib teev). Yog tias peb piv rau Glucophage thiab Siofor, nws raug nquahu tias cov kev xaiv yuav tsum ua nyob rau hauv kev pom zoo ntawm thawj.
Metformin. Cov tshuaj ua haujlwm nquag yog metformin hydrochloride hauv ib npaum ntawm 1000, 800 thiab 500 mg. Piv nrog rau cov khoom qub, nws muaj cov lej loj ntawm cov khoom siv pabcuam, uas muaj qhov tsis zoo. Qhov kom zoo dua yog tus nqi tsawg.
Lawj xeeb. Tsis zoo li Glucofage, nws pab txhawm rau txo qis cov piam thaj hauv cov ntshav los ntawm kev txhawb lub zog ntawm cov tshuaj insulin. Kev siv tsis yog tas li xwb.
Reduxin. Cov tshuaj muaj pes tsawg leeg muaj cov khoom xyaw nquag xws li sibutramine hydrochloride monohydrate thiab metformin hauv qhov ntau npaum 850 mg. Nws raug nquahu kom noj yog tias mob ntshav qab zib hom 2 nrog cov rog dhau los. Cov neeg mob uas cev nyhav tau pom zoo kom muab kev nyiam rau Glucofage.
Maninil. Nws muaj lub zog txhawb rau the-hlwb ntawm tus txiav, ua kom lub zog ntawm cov tshuaj insulin ceev. Nws siv tau tuaj yeem pom zoo nyob rau hauv rooj plaub ntawm kev ua tsis tau ntawm kev noj ntshav qab zib.
Glucovans. Hauv qhov muaj pes tsawg leeg, glibenclamide ua ke nrog metformin. Hais txog kev nyab xeeb thiab kev ua tau zoo, ob qho tshuaj yeeb tshuaj yog tib theem.
Rau menyuam yaus. Qhov tsuas yog qhov sib txawv ntawm cov tshuaj thiab cov qub yog qhov muaj sodium nyob rau hauv kev sib xyaw ntawm croscarmellose, uas ua rau muaj kev pheej hmoo ntawm kev tsis haum tshuaj.
Gliformin. Lub hauv paus ntsiab lus kho yog ua raws li kev ua kom lub siab ntev ntawm cov ntaub so ntswg nyob rau qhov cuam tshuam ntawm insulin. Nws muaj tus nqi siab thiab ntau zaus siv. Nws tuaj yeem ua raws li lwm txoj rau glucophage.
Glibomet. Muaj cov tshuaj glibenclamide thiab metformin hauv ib qhov tau tshuaj ntau npaum li 400 mg. Nws cuam tshuam tus nqi ntawm cov tshuaj insulin hauv lub cev, yog li siv nws nrog kev ceev faj. Yog tias tsis kho ntau txoj kev kho tsis pom, qhov pib ntawm kev mob ntshav qab zib yog qhov yuav tshwm sim.
Galvus. Cov kev tivthaiv tseem ceeb yog vildagliptin (50 mg). Nws tuaj yeem raug siv los kho tus mob monotherapy thiab hauv kev sib xyaw nrog metformin.
Glucobay. Piv rau Glucofage, nws tsis yog tsuas yog txawv los ntawm nws cov nqi siab (txog 800 rubles rau ib pob), tab sis kuj los ntawm lub zog ntawm nws cov txiaj ntsig kho kom zoo.
Gluconil. Nws muaj cov txheej txheem zoo sib xws ntawm kev ua, cuam tshuam rau qhov lipid metabolism thiab txhim kho cov khoom fibrinolytic ntawm cov ntshav. Nws tuaj yeem raug siv ua qauv txheej txheem ntawm metformin.

Tsawg kawg 85% ntawm cov tib neeg noj glucophage rau kev kho mob thiab tiv thaiv hom 2 mob ntshav qab zib mellitus nco txog nws cov kev kho mob siab, uas tau hais tawm hauv kev txo qis hauv qab zib hauv cov ntshav.Txawm li cas los xij, nws tsis muaj kev cuam tshuam cov beta hlwb ntawm tus txiav thiab tsis leeb lub zog ntawm cov tshuaj insulin. Cov kev xav zoo sib xws tau qhia los ntawm cov kws kho mob tshwj xeeb hauv thaj chaw endocrinology, uas pom zoo rau Glucophage rau ntau tus neeg mob ua ib feem ntawm mono- thiab kev kho mob sib xyaw.

Yog tias lwm cov kev kho mob ntshav qab zib tsis pab koj, koj tuaj yeem tshem tus kab mob hauv 1 chav kawm nrog rau Dialux (Dialux).

Cov tshuaj ntsuab zoo li no yuav ua rau muaj suab thaj kom rov zoo li qub, ua kom lub hlwb ntawm cov “insulin” ua rau lub cev tiv thaiv tsis tau cov ntshav ntawm lub cev thiab ua kom lub cev muaj kuab lom. Saib Xyuas Khoom Muag →

Txog kev kho mob pob qij txha, peb cov neeg nyeem tau siv DiabeNot siv tau zoo. Pom qhov nrov ntawm cov khoom no, peb tau txiav txim siab muab nws rau koj kom txaus siab.

Kev cuam tshuam ntawm cov txiav ua rau cov kua dej tsis txaus tsim tawm thiab ua rau muaj kev tiv thaiv ntshav qab zib hom 2. Tus kab mob ntawm hom no yog feem ntau raug rau cov neeg muaj hnub nyoog 35-40 xyoo, kev txom nyem los ntawm kev hnyav dhau thiab cov neeg uas muaj mob ua ntej rau cov ntshav qab zib hauv tsev neeg.

Tswj lub cev ntshav qab zib kom nyob qis mus yuav txo tus neeg mob ntshav qab zib uas tuaj yeem tiv thaiv tus kab mob ntshav qab zib tau zoo uas tuaj yeem tiv thaiv tau zoo los ntawm kev noj cov tshuaj Russia tshiab Dialek. Nyeem ntxiv →

Ntshav qab zib mellitus yog ib qho mob hnyav ntawm tib neeg endocrine system, xav tau kev saib xyuas tas li thiab saib xyuas tus neeg mob.

Yuav kom tawm tsam ntshav qab zib, ntau pua hom tshuaj siv, ntawm uas DIANOT tau faib, uas nws qhov kev txiav txim siab yog ua raws li kev siv cov tshuaj tiv thaiv ntuj. Cov lus piav qhia ntawm cov nyob hauv →

Mob ntshav qab zib SugaNorm yog ib hom tshuaj tsis txawv hauv keeb kwm ntawm kws kho mob kev tshawb fawb. Nws muaj lub cev ntuj ua tiav, qhov kev txiav txim ntawm kev tsom mus rau kev kho kom rov qab sib npaug ntawm cov tshuaj thiab tshem tawm qhov tsis zoo tshwm sim hauv cov ntshav qab zib.

Cov tshuaj muaj peev xwm ua kom yeej cov kab mob, uas zam kev mob nyhav thiab tswj tus neeg mob lub zog. Cov Lus Qhia Ntxiv →

Mob ntshav qab zib mellitus yog qhov thib 3 ntawm cov kab mob hauv cov neeg tuag los ntawm cov teeb meem tom qab mob qog noj ntshav thiab mob plawv.

Tus mob ntshav qab zib tau raug yuam kom saib xyuas lawv tus mob txhua hnub, ua raws li kev noj haus kev noj qab haus huv thiab siv cov kev kho mob nyuaj los ntawm cov tshuaj ib txwm muaj thiab tsis siv tshuaj. Saib Xyuas Khoom Muag →

Ji Dao Suav Cov Mob Ntshav Qab Zib Adhesive yog kev sib cais sib txawv los kho tus mob tsis tu ncua. Kev ua los ntawm daim tawv nqaij ntawm qhov sib xyaw ntawm cov ntshav thiab kev ua haujlwm ntawm cov kabmob thiab cov kabmob ntawm lub cev, nws maj mam rov qab ua cov txheej txheem hauv metabolic. Cov ntsiab lus →

Kev kho mob thiab poob phaus mob ntshav qab zib nrog kev pab ntawm cov tshuaj Siofor 500

Siofor - cov tshuaj cuam tshuam nrog cov tshuaj tiv thaiv kab mob. Cov tshuaj ua haujlwm nquag ntawm cov tshuaj yog metformin. Lub siofor yog tsim los ntawm lub tuam txhab Berlin-Chemie, uas yog ib feem ntawm lub koom haum tshuaj Italian loj Menarini Group.

Kev tsim cov tshuaj hauv qab cov npe ua lag luam Siofor tau nqa tawm hauv Tebchaws Yelemees thiab Tebchaws Europe sab hnub tuaj. Cov tshuaj no yog tsim tawm raws li GMP tus qauv, yog li ntawd qhov zoo ntawm cov tshuaj yeej ib txwm nyob theem siab. Hauv tsoomfwv Lavxias, nws muaj nyob hauv cov tshuaj ntau npaum li cas - 500 mg, 850 mg, 1000 mg.

Mechanism ntawm kev ua

Siofor yog tus neeg sawv cev ntawm chav kawm biguanide. Cov tshuaj no ua rau cov ntshav qab zib tsis tsuas yog tom qab noj mov, tab sis kuj qab zib hauv qab. Metformin tsis ua rau lub cev ua rau pancreatic beta hlwb dhau mus tsim cov tshuaj insulin, uas txhais tau tias nws tsis ua rau cov ntshav qog ntshav qab zib. Cov tshuaj no tshem tawm cov hyperinsulinemia, uas nyob rau hauv cov ntshav qab zib yog qhov ua rau kom nce phaus thiab txhim kho cov mob plawv.

Cov txheej txheem ntawm kev txo qis qab zib thaum siv Siofor npaj yog ua kom lub peev xwm ntawm cov leeg hlwb los nqus cov piam thaj los ntawm cov ntshav, ntxiv rau ua kom muaj qhov rhiab siab ntawm insulin receptors rau ntawm cov cell.

Siofor-chav kawm tshuaj txo qis tus nqi ntawm cov khoom noj haus kom ntev li sai tau los ntawm cov khoom noj hauv lub plab thiab plab hnyuv, ua kom lub zog ntawm oxidation ntawm cov roj dawb, thiab ua kom anaerobic glycolysis. Cov tshuaj no rau ntshav qab zib thiab rog rog kev tshaib plab, uas ua rau kom poob phaus. Hauv cov neeg uas tsis muaj ntshav qab zib, cov tshuaj no tsis txo cov ntshav qabzib thiab tsis tag nrho cov haujlwm saum toj no.

Tus neeg mob ntshav qab zib uas noj cov tshuaj no thiab ua raws li cov zaub mov tshwj xeeb, thiab qee zaus yuag yuag poob. Qhov tseeb tsim lub hauv paus rau kev txheeb xyuas tias metformin yog txhais tau tias ua rau poob phaus. Tab sis, qhov no tsis yog tas li.

Tom qab txhua tus, poob phaus hauv ntshav qab zib yog lub hom phiaj ntawm ob leeg mob ntshav qab zib thiab kws kho mob. Yog tias tus siofor yeej ua rau poob phaus tiag tiag, tom qab ntawd nws yuav raug txiav txim siab rau txhua tus neeg mob ntshav qab zib, thiab lawv yuav ua rau yuag nrog rhinestones. Tab sis, hmoov tsis zoo, cov neeg mob ntshav qab zib noj Siofor rau xyoo nyob rau hauv ntau qhov sib txawv los ntawm tsawg kawg 500 mg lossis 850 mg rau ib hnub txog rau ntau txog 1000 mg 3 zaug hauv ib hnub tsis tshua pom ceeb thawj cov kev poob phaus.

Xaiv xaiv

Hauv qhov chaw muag tshuaj, koj tuaj yeem pom tsuas yog peb zaug tshuaj ntawm cov tshuaj - ntsiav tshuaj ntawm 500 mg, 850 mg thiab 1000 mg. Cov koob tshuaj ntawm cov tshuaj tsuas yog xaiv los ntawm tus kws kho mob. Feem ntau, metformin pib nrog qhov koob tshuaj me tshaj - 500 mg. Ntawm cov tshuaj no lawv nres yog tias tus neeg muaj mob ntshav qab zib. Siofor 500 kuj tseem tau lees paub los ntawm cov neeg nrhiav kom poob phaus.

Yog tias tom qab ib asthiv ntawm kev noj cov tshuaj metformin 500 rau tus mob ntshav qab zib tsis muaj kev mob tshwm sim, tom qab ntawd cov koob tshuaj tau nce ntxiv thiab pauv mus rau Siofor 850, lossis lwm ntsiav tshuaj 500 mg ntxiv 12 teev tom qab noj thawj 500 mg ntsiav tshuaj ntawm cov tshuaj no. Txhua 7 hnub, 500 mg ntawm metformin yog maj mam ntxiv rau qhov siab tshaj plaws tiv thaiv thiab ua kom zoo.

Nrog rau qhov nce ntawm cov tshuaj no, cov kev mob tshwm sim tuaj yeem tshwm sim, uas yuav tsum tau txhaj koob tshuaj rau cov khoom ntim ntawm yav dhau los. Ua haujlwm dhau sijhawm, koj yuav tsum rov sim ua kom qhov kev noj tshuaj ntau ntxiv rau qhov muaj txiaj ntsig zoo.

Cov ntsiav tshuaj Siofor yog zuaj tsis muaj kev zom thiab ntxuav nrog kom huv si nrog dej huv. Nws yog qhov zoo dua los ua qhov no tam sim ntawd tom qab noj mov lossis tam sim ntawd thaum noj mov. Yog tias cov tshuaj no tau sau tseg hauv 500 mg, nws tau noj ib zaug, thaum yav tsaus ntuj - qhov no txo qhov kev pheej hmoo ntawm kev phiv. Yog tias 1000 mg rau ib hnub twg tau sau tseg, tom qab ntawv no yuav tsum tau faib 2 koob tshuaj 500 mg rau ib zaug, tom qab 12 teev, thaum sawv ntxov thiab yav tsaus ntuj.

Tus kws kho mob tuaj yeem tshaj tawm txog 1000 mg 3 zaug hauv ib hnub, tab sis, raws li txoj cai, 1000 mg 2 zaug hauv ib hnub yog txaus rau kev kho mob ib txwm muaj ntshav qab zib thiab poob phaus. Nws yog qhov tseem ceeb heev uas thaum lub sijhawm ntawm txoj kev kho nrog Siofor-tshuaj siv tshuaj, ua ntu zus qee qhov kev sim uas muaj kev cuam tshuam ntawm kev ua haujlwm ntawm lub raum thiab mob siab. Namely, kev kuaj ntshav dav dav, ib qho kev kuaj ntshav biochemical (creatinine, daim siab ua haujlwm siab).

Thaum twg tsis xav coj

Yog tias, txawm hais tias tag nrho cov lus ceeb toom thiab tshuaj xyuas, koj tseem txiav txim siab kom yuag nrog cov tshuaj no. Nco ntsoov tias koj yuav tsum ua tib zoo nyeem thiab khaws cov lus qhia uas cov neeg tsim khoom lag luam tso rau hauv txhua lub thawv ntawm cov tshuaj no.

Nco ntsoov! Ib tus neeg noj Siofor, txawm tias qhov tsawg kawg yog 500 mg, yuav tsum tso tseg kev haus dej cawv. Kev sib xyaw ua ke ntawm cov tshuaj no thiab dej cawv ua rau muaj kev puas tsuaj rau lub siab.

Siofor tseem tseem contraindicated yog tias koj muaj:

ntshav qab zib hom 1
lub cev qhuav dej
mob raum lossis mob siab,
cev xeeb tub, lactation,
tej SARS, khaub thuas, mob ntsws, mob ntsws thiab lwm yam kev kis mob, lossis mob ntsws,
siab lub cev kub
phais mob los yog koj raug mob,
kev cuam tshuam ntawm cov hlab plawv system, myocardial infarction,
hlav hlav
haus cawv ntev,
kuaj cov ntshav qab zib lossis coma,
ketoacidosis.

Cov ntsiav tshuaj no tsis tau sau tseg rau cov menyuam yaus thiab txwv tsis pub siv rau hauv cov neeg laus dua 60 xyoo. Metformin yuav tsum tsis txhob ua yog tias koj nquag koom nrog kev ua kis las lossis ua haujlwm lub cev. Txwv tsis pub, qhov no yuav ua rau txoj kev txhim kho ntawm cov lus tshaj tawm hais tawm.

Zawv zawg thiab tshuaj xyuas

Tus nom cov lus qhia rau Siofor hais txog kev siv cov tshuaj noj haus no tsis hais dab tsi. Kev siv tshuaj rau nws tus kheej xws li cov tshuaj txhaum loj kuj tsis tsim nyog nws. Nws yog ib qho tsim nyog sab laj nrog tus kws kho mob thiab nug nws txog qhov ua tau los ntawm kev muab tshuaj rau cov tshuaj no rau qhov poob phaus. Tej zaum tus kws kho mob, hais txog nws kev paub dhau los, kev tshuaj xyuas tus neeg mob thiab cov txiaj ntsig ntawm koj txoj kev kuaj mob, yuav pom zoo rau koj cov tshuaj no rau qhov poob phaus tsawg kawg hauv 500 tsis ntau tshaj 3 lub hlis.

Kev txheeb xyuas ntawm kev poob phaus nrog siofor ua pov thawj tias tsuas yog cov neeg uas ua raws li cov zaub mov tsis muaj calorie tsawg thiab txwv tsis pub cov khoom noj zom tau yooj yim yuav ua kom yuag.

Qhov uas neeg to taub yuam kev heev

Tswvyim hais ua dabneeg 1. Pab kom poob ceeb thawj sib zog

Kev txheeb xyuas ntawm kev poob phaus kiag li tsis zoo rau zaj dab neeg no. Kev ua kom yuag zoo, kev noj zaub mov nrog kev txwv kev qab zib, hmoov, rog thiab kib yog xav tau. Ib qho siofor nrog cov phaus ntxiv tuaj yeem tiv tsis tau.

Tswvyim hais ua dabneeg 2. Tiv thaiv kev mob siab rau khoom qab zib

Siofor tsis cuam tshuam rau cov neeg nyiam saj thiab nyiam ntawm tus neeg. Qhov nrov ntawm cov tshuaj no rau cov kev poob phaus poob vim yog qhov ntau ntawm cov neeg tsis txaus siab tshuaj xyuas.

Tswvyim hais ua dabneeg 3. Cov yeeb tshuaj tsis haum xeeb

Kev soj ntsuam ntawm cov kws tshawb fawb tau nce hais tias siofor cuam tshuam txog cov metabolism hauv tus neeg noj qab haus huv. Vim tias muaj ntau qhov tshwm sim loj thaum siv cov tshuaj no. ntau thiab ntau tus kws kho mob tau pom zoo tsim cov tshuaj no rau hauv cov npe tshuaj.

Yog tias koj tuaj yeem poob phaus nrog metformin tsuas yog tias koj ua raws li kev noj zaub mov nruj, yog li vim li cas them nyiaj ntau dua thiab muaj kev phom sij rau koj tus kheej hauv daim ntawv ntawm kev phiv los ntawm cov tshuaj no? Hmoov tsis zoo, Siofor, zoo li lwm cov tshuaj noj tsis tau, tsis tuaj yeem dhau los ua ib qho txuj ci tseem ceeb uas yooj yim, yooj yim thiab tas mus li tshem tawm cov phaus ntxiv.

Kev cuam tshuam nrog lwm yam tshuaj

Cov tshuaj tiv thaiv ntawm cov nyhuv hypoglycemic ntawm cov tshuaj yog angiotensin hloov enzyme inhibitors (captopril, enalapril), H2-histamine receptor blockers (cimetidine), tshuaj tua kab mob (miconazole, fluconazole), tsis siv tshuaj tiv thaiv tsis haum tshuaj (NSAIDs), phenylbenzofenb ), tiv thaiv kab mob ntsws (ethionamide), salicylates, coumarin anticoagulants, anabolic steroids, beta-blockers, monoamine oxidase inhibitors, sulfonamides Kev nqis tes ua qab nthab hais, cyclophosphamide, biguanides, chloramphenicol, fenfluramine, acarbose, fluoxetine, guanethidine, pentoxifylline, tetracycline, theophylline, tubular secretion blockers, reserpine, bromocriptine, disopyramide, pyridoxine, insulin, allopurinol.
Barbiturates, glucocorticosteroids, adrenostimulants (epinephrine, clonidine), cov tshuaj antiepileptic (phenytoin), BMCC, carbonic anhydrase inhibitors (acetazolamide), thiazide diuretics, chlortalidone, furosemide, triazinazide, diamaz ainine aeneine aineisineineine. salbutamol, terbutaline, glucagon, rifampicin, cov thyroid hormones, cov roj ntsha lithium, cov koob tshuaj nicotinic ntau ntau, chlorpromazine, tshuaj muaj qhov ncauj thiab estrogens.
Zis acidifying tshuaj (ammonium chloride, calcium chloride, ascorbic acid nyob rau hauv cov koob tshuaj loj) txhim kho cov nyhuv los ntawm kev txo qis ntawm kev sib cais thiab nce kev rov kho dua ntawm glibenclamide.
Ethanol nce txoj kev pheej hmoo ntawm kev tsim cov mob lactic acidosis.
Furosemide nce lub siab ntau nyob rau hauv cov ntshav (Cmax) ntawm metformin los ntawm 22%.
Cov khoom noj Nifedipine nce ntxiv kev nqus, Cmax, ua rau qeeb ntawm kev txiav tawm ntawm metformin. Cov tshuaj Cationic (amiloride, digoxin, morphine, procainamide, quinidine, quinine, ranitidine, triamteren thiab vancomycin) zais cia rau hauv cov menyuam ua lag luam sib tw rau tubular thauj cov tshuab thiab, nrog kev kho mob ntev, tuaj yeem nce Cmax ntawm metformin los ntawm 60%.
Metformin txo Cmax thiab T½ ntawm furosemide los ntawm 31 thiab 42.3%, feem.