Lawj Xeeb MV

Lawj Xeeb MV (Mob ntshav qab zib MR): 2 tshuaj xyuas ntawm tus kws kho mob, 3 tshuaj xyuas cov neeg mob, cov lus qhia rau kev siv, analogues, infographics, 1 daim ntawv tso tawm.

Kev tshuaj xyuas ntawm cov kws khomob txog ntshav qab zib

Nrog rau decompensation ntawm cov ntshav qab zib, cov tshuaj compensates rau glycemia txig. Kev tso tawm hloov kho tiv thaiv kev mob ntshav qab zib, yog li ntawd, cov tshuaj yog tsim nyog rau cov neeg laus, nrog rau cov neeg mob ntawm cov kab mob ntawm cov hlab plawv.

Tsis tshua muaj, tab sis tuaj yeem ua rau ntshav qab zib tsawg.

Kuv siv cov tshuaj heev nyob rau hauv kuv xyaum. Tsim nyog tus nqi, zoo heev efficiency.

Cov tshuaj "Diabeton MV" tau siv ntau yam tshuaj ntawm 30 lossis 60 mg. Cov no yog hloov kho tawm ntsiav tshuaj. Cov tshuaj muaj ib tug heev zoo thiab txawm profile ntawm kev txiav txim. Tsis muaj kev mob tshwm sim, cov nyhuv ntawm cov tshuaj pib tom qab lub sijhawm sai. Tsim tsim los kho mob ntshav qab zib.

Tus Neeg Saib Xyuas Tus Mob Ntshav Qab Zib MV

Kuv tus txiv muaj siab qab zib. Tau ntau xyoo, lawv tau nrhiav tshuaj uas yuav txo qis nws qab zib thiab, qhov tseem ceeb tshaj plaws, ua rau nws qib tsis nyob zoo. Hauv kev sib tham tom ntej nrog tus kws kho mob uas tuaj koom, peb tau raug qhia cov tshuaj "Diabeton MV". Tom qab ib hlis txoj kev noj tshuaj, qab zib rov qab nyob rau qhov qub. Tam sim no kuv tus txiv muaj 8,2 hli. Qhov no, ntawm chav kawm, yog nce qib me ntsis. Tab sis nws zoo dua li 13-15 hli uas tau ua ntej.

Kws kho mob "Diabeton" noj tshuaj ntawm 60 mg rau ib hnub, tsis tshua zoo txo. Thaum sawv ntxov muaj qab zib 10-13. Tom qab ntawd tus kws kho mob tau nce qhov ntau dua rau 90 mg (1.5 tab). Tam sim no thaum sawv ntxov, thaum kuv ntsuas ntshav qab zib, nws yog txawm 6. Kuv yuav tsum hais tias ntau ntxiv nyob ntawm seb kuv nruj rau kev noj haus. Tsuas zoo tib yam 6 thaum ntawd thaum tseem tsis tau noj muaj teeb meem. Ntawm chav kawm, ntxiv rau me ntsis kev tawm dag zog.

Kuv tau noj nws rau ib xyoos, qhov ua tau zoo, qhov pom tau pom tseeb thiab nrawm. Cov kev mob tshwm sim tsis tshwm sim. Zoo tshuaj kho.

Kws Tshuaj

Tus neeg sawv cev ntawm tus mob ntshav qab zib ntau ntau, yog sulfonylurea derivative ntawm lub cim thib ob. Pab tsim lub cev kom zais cov kua ntshav los ntawm β-hlwb ntawm cov txiav. Tsub qhov rhiab heev ntawm peripheral cov ntaub so ntswg rau insulin. Thaj, nws pab txhawb kev ua si ntawm intracellular enzymes (hauv tshwj xeeb, nqaij glycogen synthetase). Txo lub sijhawm ua ntu zus los ntawm lub sijhawm noj mov kom pib lub insulin secretion. Rov kho lub sijhawm thaum ntxov ntawm insulin secretion, txo qis ncov tom qab ntawm hyperglycemia.

Glyclazide txo cov platelet adhesion thiab kev sib sau, maj mam txo qis kev txhim kho ntawm parietal thrombus, thiab nce vascular fibrinolytic kev ua si. Normalizes vascular permeability. Nws muaj cov khoom ua rau anti-atherogenic: nws txo qis cov roj (Ch) thiab LDL-C hauv cov ntshav, nce qhov nce ntawm HDL-C thiab kuj txo cov dawb radicals. Tiv thaiv kev txhim kho ntawm microthrombosis thiab atherosclerosis. Txhim kho microcirculation. Txo kom vascular rhiab heev rau adrenaline.

Nrog rau cov ntshav qab zib nephropathy nrog kev siv lub sijhawm ntev ntawm gliclazide, qhov tseem ceeb txo qis rau cov proteinuria tau sau tseg.

Cov Tshuaj Pharmacokinetics

Tom qab kev tswj hwm ntawm qhov ncauj, nws nrawm los ntawm lub plab zom mov. C_max hauv cov ntshav tau mus txog kwv yees li 4 teev tom qab noj ib koob ntawm 80 mg.

Plasma protein khi yog 94.2%. V_d - txog 25 l (0.35 l / kg lub cev hnyav).

Nws yog metabolized hauv lub siab nrog kev tsim ntawm 8 metabolites. Lub ntsiab metabolite tsis muaj qhov teebmeem hypoglycemic, tab sis muaj cov nyhuv ntawm microcirculation.

T_1/2 - 12 teev .Nws yog txau feem ntau los ntawm lub raum ua cov tshuaj metabolites, tsawg dua 1% yog tawm hauv cov zis tsis hloov pauv.

Daim ntawv tso tawm

Cov hloov kho-tso cov ntsiav tshuaj yog dawb, oblong, sau rau ntawm ob sab: ntawm ib tus yog lub logo ntawm tuam txhab, nyob rau lwm qhov - "DIA30".

Cov muaj mob: calcium calcium phosphate dihydrate, maltodextrin, hypromellose, magnesium stearate, anhydrous colloidal silicon dioxide.

30 pcs - hlwv (1) - pob khoom los ntawm cardboard.
30 pcs - hlwv (2) - pob khoom los ntawm cardboard.

Kev sib txuam

Cov nyhuv hypoglycemic ntawm gliclazide muaj zog nrog kev siv ib txhij nrog pyrazolone derivatives, salicylates, phenylbutazone, tshuaj tua kab mob sulfonamide, theophylline, caffeine, MAO inhibitors.

Kev siv tib lub sijhawm tsis xaiv cov beta-blockers ua rau kom muaj kev txhim kho hypoglycemia ntau ntxiv, thiab tseem tuaj yeem npog tachycardia thiab tes tshee, cov yam ntxwv ntawm hypoglycemia, thaum tawm hws yuav nce.

Nrog rau kev siv tib lub ntsej muag ntawm gliclazide thiab acarbose, ib qho kev tiv thaiv hypoglycemic ntxiv tau pom.

Cimetidine tsub kom ntau ntxiv ntawm gliclazide hauv ntshav, uas tuaj yeem ua rau mob ntshav qab zib tsawg (CNS kev nyuaj siab, qhov tsis hnov ​​qab).

Nrog rau kev siv ua ke nrog GCS (suav nrog cov ntawv rau kev siv rau sab nraud), diuretics, barbiturates, estrogens, progestins, ua ke cov tshuaj estrogen-progestogen, diphenin, rifampicin, cov nyhuv hypoglycemic ntawm glyclazide txo qis.

Sab sij huam

Los ntawm lub plab zom mov: tsis tshua muaj - tsis nco qab, ntuav, ntuav, raws plab, mob epigastric.

Los ntawm cov kab mob hemopoietic: nyob rau qee kis - thrombocytopenia, agranulocytosis lossis leukopenia, ntshav liab (feem ntau yog thim rov qab).

Los ntawm cov kab ke endocrine: nrog kev siv ntau dhau - hypoglycemia.

Ua xua: tawv nqaij ua pob, khaus.

Hom 2 mob ntshav qab zib mellitus nrog cov tsis muaj txiaj ntsig ntawm kev kho zaub mov noj, ua kom lub cev thiab yuag poob.

Kev tiv thaiv ntawm cov teeb meem ntawm hom 2 mob ntshav qab zib mellitus: txo kev pheej hmoo ntawm microvascular (nephropathy, retinopathy) thiab mob macrovascular (myocardial infarction, mob stroke).

Cov lus qhia tshwj xeeb

Gliclazide yog siv los kho cov ntshav qab zib tsis yog-insulin nyob rau hauv kev sib xyaw nrog kev noj zaub mov kom muaj calorie tsawg, noj cov zaub mov qis.

Thaum kho, koj yuav tsum tau soj qab xyuas kom cov qib ntawm cov piam thaj hauv cov ntshav ntawm lub plab thiab tom qab noj mov, kev hloov pauv txhua hnub nyob hauv qib qabzib.

Kev phais mob lossis kev decompensation ntawm ntshav qab zib mellitus, nws yog ib qho tsim nyog yuav tsum coj mus rau hauv tus account qhov tau los ntawm kev siv tshuaj insulin.

Nrog rau kev txhim kho cov ntshav qog ntshav qab zib, yog tias tus neeg mob nco qab, qabzib (lossis kua qab zib) yog tshuaj hauv. Yog tias tsis nco qab, tso ntshav qabzib lossis glucagon sc, intramuscularly lossis intravenously raug tswj hwm. Tom qab nws rov qab nco qab, nws yog ib qho tsim nyog yuav tsum tau muab cov neeg mob zaub mov nplua nuj nyob hauv cov carbohydrates kom tsis txhob rov qab txhim kho kev mob ntshav qab zib.

Nrog rau kev siv kev sib txuas ntawm gliclazide nrog verapamil, yuav tsum tau saib xyuas cov ntshav qabzib ntau ntxiv, nrog acarbose, ua tib zoo saib xyuas thiab kho cov tshuaj regimen ntawm hypoglycemic tus neeg sawv cev yog qhov yuav tsum tau ua.

Kev siv ua ke ntawm gliclazide thiab cimetidine tsis pom zoo.