Glimecomb - ob yam tshuaj rau hom ntshav qab zib hom 2

Muaj ib ntsiav tshuaj:

cov tshuaj nquag: metformin hydrochloride hais txog 100% tshuaj-500 mg, glycazide hais txog 100% tshuaj-40 mg,

tus zam: sorbitol, povidone, croscarmellose sodium, magnesium stearate.

Cov ntsiav tshuaj los ntawm dawb rau dawb nrog creamy lossis daj daj zas, tiaj tus-cylindrical, nrog bevel thiab muaj kev pheej hmoo. Lub xub ntiag ntawm "marbling" raug tso cai.

Pab pawg ntseeg PHARMACOTHERAPEUTIC:

ua ke cov tshuaj hypoglycemic rau kev siv hauv qhov ncauj (biguanide + sulfonylurea pawg npaj)

ATX CODE: A10BD02

PHARMACOLOGICAL COV NTAUB NTAWV Cov Chaw Muag Tshuaj Ua Lag Luam.

Glimecomb® yog kev sib txuam ruaj ruaj ntawm ob lub qhov ncauj hypoglycemic ntawm ntau yam pharmacological pawg: glyclazide thiab metformin. Nws muaj pancreatic thiab non-pancreatic teebmeem.

Gliclazide txhawb kev tawm tsam cov kua dej los ntawm cov kua txiav ntshav, nce rhiab ntawm cov ntaub so ntswg mus rau insulin. Tsim kho kev ua ub no ntawm intracellular enzymes - nqaij hlav glycogen synthetase. Nws rov kho lub sijhawm thaum kawg ntawm cov tshuaj insulin secretion, txo lub sijhawm ncua sijhawm ntawm lub sijhawm noj mov kom txog thaum pib lub cev insulin, thiab txo qis postprandial hyperglycemia. Ntxiv nrog rau cuam tshuam rau cov metabolism hauv kev ua haujlwm, nws cuam tshuam microcirculation, txo platelet adhesion thiab kev sib sau ua ke, qeeb kev txhim kho ntawm parietal thrombosis, normalizes vascular permeability thiab inhibits kev txhim kho ntawm microthrombosis thiab atherosclerosis, rov qab cov txheej txheem ntawm physiological parietal fibrinolysis, thiab tawm tsam cov tshuaj tiv thaiv muaj zog rau vascular adrenal. Txo cov kev loj hlob ntawm cov ntshav qab zib retinopathy nyob rau theem tsis-loj hlob, nrog rau cov ntshav qab zib uas muaj lub cev ntev nrog kev siv ntev, qhov tseem ceeb txo qis rau cov proteinuria tau sau tseg. Nws tsis ua rau muaj qhov nce hauv lub cev qhov hnyav, vim nws muaj lub luag haujlwm tseem ceeb ntawm cov tshuaj tiv thaiv thaum ntxov thiab tsis ua rau hyperinsulinemia, nws pab txo lub cev qhov hnyav hauv cov neeg mob rog, ua raws li kev noj zaub mov zoo.

Metformin belongs rau cov pab pawg ntawm cov loj loj. Nws txo cov concentration ntawm cov piam thaj hauv cov ntshav los ntawm inhibiting gluconeogenesis nyob rau hauv daim siab, txo qhov nqus ntawm cov piam thaj los ntawm kev mob plab thiab nce nws txoj kev siv hauv cov ntaub so ntswg. Txo cov kev xav hauv cov ntshav cov ntshav ntawm triglycerides, cov roj (cholesterol) thiab cov lipoproteins uas tsis muaj ntau (txiav txim ntawm lub plab) thiab tsis hloov lub siab ntawm lipoproteins ntawm lwm qhov uas muaj ntau yam. Pab ua kom ruaj khov lossis txo lub cev qhov hnyav. Thaum tsis muaj cov tshuaj insulin nyob rau hauv cov ntshav, kev kho mob tsis pom tseeb. Kev ua kom lub cev ntshav qis tsis tuaj yeem ua. Txhim kho cov khoom fibrinolytic ntawm cov ntshav vim los ntawm kev tsuj ntawm ib qho inhibitor ntawm activator profibrinolysin (plasminogen) cov ntaub so ntswg hom.

Gliclazide. Kev tshem tawm yog qhov siab. Tom qab qhov ncauj tswj hwm ntawm 40 mg, qhov siab tshaj plaws nyob rau hauv cov ntshav plasma tau mus txog tom qab 2-3 teev thiab ntau npaum li 2-3 μg / ml. Kev sib txuas lus nrog cov protein ntshav yog 85-97%. Qhov kev tshem tawm ib nrab-lub neej yog 8-20 teev.Nws yog metabolized hauv lub siab. Nws yog tawm hauv feem ntau hauv daim ntawv ntawm metabolites los ntawm ob lub raum - 70%, los ntawm txoj hnyuv - 12%. Hauv cov neeg laus, cov kab mob tseem ceeb hauv kev hloov pauv ntawm cov tshuaj pharmacokinetic tsis tau pom. Metformin. Kev Pom Zoo - 48-52%. Sai sai nqus nyob rau hauv lub gastrointestinal ib ntsuj av. Kev siv lub cev tsis txaus ntseeg (ntawm lub plab khoob) yog 50-60%, kev noj zaub mov nrog zaub mov txo qhov kev xav ntau los ntawm 40% thiab ua rau nws ua tiav tau los ntawm 35 feeb. Plasma concentration tau txog tom qab 1.81-2.69 teev thiab tsis ntau tshaj 1 μg / ml. Kev sib txuas lus nrog cov protein ntshav yog qhov tsis txaus ntseeg, nws tuaj yeem khaws hauv cov ntshav liab. Ib nrab-lub neej yog 6,2 teev .Nws yog tawm los ntawm lub raum, feem ntau tsis hloov pauv (glomerular filtration thiab tubular secretion) thiab los ntawm cov hnyuv (txog 30%).

INDICATIONS RAU SIV

• Hom 2 ntshav qab zib mellitus nrog qhov tsis muaj txiaj ntsig ntawm kev kho kev noj haus, kev tawm dag zog thiab kev kho yav dhau los nrog metformin lossis gliclazide.

• Hloov chaw ntawm kev kho mob yav dhau los nrog ob yam tshuaj (metformin thiab gliclazide) hauv cov neeg mob ntshav qab zib hom 2 uas muaj cov ntshav qabzib ruaj thiab tswj tau ntshav qabzib.

TSWJ SIB LWM

• muaj qhov tsis haum xeeb rau metformin, glyclazide lossis lwm yam sulfonylurea derivatives, thiab ntxiv rau cov tshuaj pab,

• hom ntshav qab zib 1

• ketoacidosis uas mob ntshav qab zib, mob ntshav qab zib precoma, mob ntshav qab zib coma

• mob raum,

• mob hnyav uas tuaj yeem ua rau lub raum pauv hloov: lub cev qhuav dej, ua mob hnyav, ceeb,

• mob hnyav los yog mob mus ntev nrog cov nqaij mos hypoxia: mob plawv lossis ua pa tsis ua haujlwm, tsis ntev los no myocardial infarction, poob siab,

• cev xeeb tub, lub sijhawm pub mis niam,

• ua hauj lwm ib txhij ntawm miconazole,

• cov kab mob kis, kev cuam tshuam loj ntawm kev phais mob, kev raug mob, kub hnyiab thiab lwm yam mob uas yuav tsum muaj kev kho mob,

• haus dej cawv tsis qaug cawv, qaug cawv kom qaug,

• lactic acidosis (suav nrog keeb kwm)

• siv tsawg kawg 48 teev ua ntej thiab nyob rau hauv 48 teev tom qab ua kev tshawb fawb radioisotope lossis xoo hluav taws xob nrog kev qhia ntawm iodine uas muaj qhov nruab nrab tsis sib thooj,

• ua raws cov khoom noj uas tsis muaj calories ntau (tsawg dua 1000 calories / hnub).

Nws tsis pom zoo kom siv cov tshuaj rau cov neeg laus dua 60 xyoo uas ua haujlwm lub cev hnyav, uas cuam tshuam nrog kev pheej hmoo ntawm kev tsim mob lactic acidosis hauv lawv.

Nrog saib xyuas

Cov tsos mob kub taub hau, adrenal tsis txaus, kev ua haujlwm ntawm lub raum pituitary anterior, cov thyroid mob nrog kev ua haujlwm tsis zoo.

DAIM NTAWV THOV KEV TXHAUM CAI LOSSIS QAB ZIB PW

Thaum cev xeeb tub, kev siv tshuaj Glimecomb® yog contraindicated. Thaum npaj kev cev xeeb tub, nrog rau muaj xwm txheej hauv cev xeeb tub thaum lub sijhawm noj cov tshuaj Glimecomb®, cov tshuaj yuav tsum tsis ua haujlwm ntxiv thiab kev kho mob insulin yuav tsum tau kho.

Glimecomb ® yog qhov sib txuam hauv kev pub niam mis, txij li thaum cov tshuaj muaj peev xwm nkag mus rau hauv niam mis. Hauv qhov no, koj yuav tsum hloov mus rau kev siv tshuaj insulin lossis txwv kev pub niam mis.

KHAWV KOOB THIAB KEV COB QHIA

Cov tshuaj yog siv qhov ncauj, thaum lub sijhawm lossis tom qab noj mov tas. Qhov ntau thiab tsawg ntawm cov tshuaj tau txiav txim los ntawm tus kws kho mob tshwj xeeb rau txhua tus neeg mob, nyob ntawm seb cov ntshav nyob ntawm seb ntau npaum li cas.

Feem ntau tso thawj zaug yog 1-3 ntsiav tshuaj hauv ib hnub nrog maj mam xaiv cov koob tshuaj kom txog thaum them nyiaj ruaj khov ntawm tus kabmob.

Feem ntau siv tshuaj ntawd noj 2 zaug hauv ib hnub (sawv ntxov thiab yav tsaus ntuj). Qhov siab tshaj plaws niaj hnub noj yog 5 ntsiav tshuaj.

Tej yam tsis zoo

Los ntawm sab hauv cov metabolism: nyob rau hauv kev ua txhaum ntawm txoj kev noj tshuaj kom zoo thiab noj zaub mov tsis zoo, ua rau lub cev tsis muaj ntshav qab zib (mob taub hau, zoo li nkees nkees, tshaib plab, tawm hws ntau, tsis muaj zog, txhaws ntswg, kiv taub hau, tsis muaj kev sib koom tes ntawm kev txav mus ib ntus, cov leeg mob hauv lub cev, nrog kev nce siab ntawm hypoglycemia, tus neeg mob yuav plam tus kheej thiab tswj tau. nco qab), nyob rau qee kis - lactic acidosis (tsis muaj zog, myalgia, ua pa nyuaj, qaug zog, mob plab, hypothermia, txo ntshav siab, reflex b radiarrhythmia).

Los ntawm lub plab zom mov: dyspepsia (xeev siab, zawv plab, zoo nkaus li qhov hnyav hauv qhov epigastrium, saj "xim hlau" hauv qhov ncauj), tsis qab los noj mov - muaj mob tsawg dua nrog cov tshuaj thaum noj mov, tsis tshua muaj - mob siab rau daim siab (mob siab, mob sib daj sib deev - yuav tsum tau tshem tawm yeeb tshuaj, nce kev ua haujlwm ntawm "mob siab" transaminases, alkaline phosphatase).

Los ntawm cov ntshav hemopoietic plab hnyuv siab raum: tsis tshua muaj - inhibition ntawm cov pob txha mob hematopoiesis (mob ntshav qab zib, thrombocytopenia, leukopenia).

Ua xua: khaus, urticaria, maculopapular pob.

Yog tias muaj kev mob tshwm sim, qhov tshuaj yuav tsum raug txo lossis cov tshuaj txuas mus ntxiv ib ntus.

Lwm yam: pom kev pom.

Cov kev mob tshwm sim ntawm sulfonylurea derivatives: erythropenia, agranulocytosis, hemolytic anemia, pancytopenia, kev tsis haum vasculitis, ua rau lub siab ua rau lub siab tsis ua haujlwm.

OVERDOSE

Kev noj tshuaj ntau dhau lossis muaj qhov ua rau muaj kev pheej hmoo tuaj yeem cuam tshuam kev txhim kho ntawm cov kab mob lactic acidosis, vim tias metformin yog ib feem ntawm cov tshuaj. Yog tias cov tsos mob ntawm tus kab mob lactic acid tshwm sim, tsum tsis txhob siv tshuaj. Lactic acidosis yog kev mob uas yuav tsum tau txais kev kho mob xwm txheej ceev, kev kho mob ntawm cov kab mob lactic acidosis yuav tsum tau ua nyob hauv tsev kho mob. Qhov kev kho mob uas zoo tshaj plaws yog hemodialysis. Ib qho kev noj qab haus huv kuj tseem tuaj yeem ua rau muaj kev txhim kho hypoglycemia vim muaj cov gliclazide hauv kev npaj. Nrog rau cov ntshav qog ntshav qab zib me lossis mob ntshav qab zib ntau, cov piam thaj (dextrose) los yog cov kua qab zib yog noj ntawm qhov ncauj. Thaum muaj mob ntshav qab zib tsawg (tsis nco qab lawm), ib qho 40% dextrose (qabzib) tshuaj lossis glucagon muab tso rau hauv qhov quav, ua kom sai, subcutaneously. Tom qab nws rov qab nco qab, tus neeg mob yuav tsum tau muab cov zaub mov nplua nuj nyob hauv cov khoom noj kom hnyav kom tsis txhob muaj kev rov qab txhim kho ntawm hypoglycemia.

INTERACTION NROG LWM COV MEDICINES

Cov tshuaj tiv thaiv ntawm cov nyhuv hypoglycemic ntawm cov tshuaj yog angiotensin hloov enzyme inhibitors (captopril, enalapril), H2-histamine receptor blockers (cimetidine), tshuaj tua kab mob (miconazole, fluconazole), tsis siv tshuaj tiv thaiv tsis haum tshuaj (NSAIDs), phenylbenzofenb ), tiv thaiv kab mob ntsws (ethionamide), salicylates, coumarin anticoagulants, anabolic steroids, beta-blockers, monoamine oxidase inhibitors, sulfonamides Kev nqis tes ua qab nthab hais, cyclophosphamide, chloramphenicol, fenfluramine, fluoxetine, guanethidine, pentoxifylline, tetracycline, theophylline, tubular secretion blockers, reserpine, bromocriptine, disopyramide, pyridoxine, lwm yam hypoglycemic tshuaj (acarbose, biguanides, insulin, etc.), allopurinol oxytetracycline.

Barbiturates, glucocorticosteroids, adrenergic agonists (epinephrine, clonidine), cov tshuaj tiv thaiv kab mob (phenytoin), qeeb calcium calcium blockers, carbonic anhydrase inhibitors (acetazolamide), thiazide diuretics, chlortalidone, trifenazole azeneazide, azinazolez, azinazolez , morphine, ritodrine, salbutamol, terbutaline, glucagon, rifampicin, cov thyroid hormones, cov roj ntsha lithium, cov koob tshuaj nicotinic acid ntau dua, chlorpromazine, tshuaj tiv thaiv muaj qhov ncauj thiab estrogens.

Ua rau muaj kev pheej hmoo ntawm kev tsim ventricular extrasystoles thiab thiab ntawm keeb kwm ntawm mob glycosides. Cov tshuaj noj uas ua kom cov leeg hlwb hematopoiesis ua rau muaj kev pheej hmoo ntawm myelosuppression.

Ethanol nce txoj kev pheej hmoo ntawm kev tsim cov mob lactic acidosis.

Metformin txo cov kev xav ntau hauv cov ntshav (C max) thiab T 1 / 4furosemide los ntawm 31 thiab 42.3%, feem. Furosemide nce C max metformin los ntawm 22%.

Nifedipine nce ntxiv kev nqus, C max, ua kom qis qis ntawm kev nthuav tawm ntawm metformin.

Cov tshuaj Cationic (amiloride, digoxin, morphine, procainamide, quinidine, quinine, ranitidine, triamteren thiab vancomycin) zais cia rau hauv cov tubules sib tw rau cov tub ntxhais thauj khoom thiab, nrog kev kho mob ntev, tuaj yeem nce C max metformin los ntawm 60%.

COV LUS QHIA TSHWJ XEEB

Kev kho mob nrog Glimecomb® tau tsuas yog ua ke nrog cov khoom noj uas tsis muaj calorie tsawg, carb qis. Nws yog ib qho tsim nyog yuav tsum tau soj ntsuam qib ntshav qabzib hauv cov ntshav ntawm lub plab khoob thiab tom qab noj mov, tshwj xeeb tshaj yog nyob rau thawj hnub ntawm kev kho mob nrog tshuaj.

Glimecomb ® tuaj yeem tsuas yog kho rau cov neeg mob tau txais kev noj mov tsis tu ncua, uas tsim nyog noj tshais, kom ntseeg tau tias muaj cov zaub mov carbohydrates kom txaus.

Thaum sau tshuaj, nws yuav tsum tau yug los rau hauv lub siab hais tias vim kev noj cov tshuaj sulfonylurea derivatives, hypoglycemia tuaj yeem txhim kho, thiab hauv qee kis muaj mob hnyav thiab ntev, yuav tsum tau pw hauv tsev kho mob thiab ntshav qabzib rau ob peb hnub. Kev mob ntshav qab zib feem ntau pib txhim kho nrog cov zaub mov tsis muaj calorie, tom qab ua haujlwm ntev lossis ua kom ib ce muaj zog, tom qab haus dej haus cawv, lossis thaum noj ntau yam tshuaj hypoglycemic nyob rau tib lub sijhawm.

Txhawm rau kom zam dhau kev txhim kho hypoglycemia, yuav tsum ceev faj thiab xaiv cov koob tshuaj yuav tsum tau, nrog rau kev muab cov neeg mob nrog cov ntaub ntawv tiav ntawm cov kev kho mob uas tau thov.

Nrog rau kev tawm dag zog ntawm lub cev thiab lub siab, thaum hloov kev noj zaub mov, yuav tsum tau txhaj tshuaj ntawm Glimecomb® tsim nyog koob tshuaj.

Tshwj xeeb tshaj yog nkag siab rau kev txiav txim ntawm cov tshuaj hypoglycemic: cov neeg laus, cov neeg mob uas tsis tau txais kev noj zaub mov zoo, nrog rau lub xeev tsis muaj zog txaus, cov neeg mob kev txom nyem los ntawm pituitary-adrenal tsis txaus. Beta-blockers, clonidine, reserpine, guanethidine tuaj yeem npog qhov chaw kho mob tshwm sim ntawm hypoglycemia.

Cov neeg mob yuav tsum ceeb toom qhia txog kev pheej hmoo yuav muaj ntshav qab zib tsawg nyob rau hauv muaj ethanol, NSAIDs, thiab tshaib plab.

Kev phais mob thiab kev raug mob loj, kev kub nyhiab, kev kis kab mob nrog febrile syndrome yuav tsum muaj kev tshem tawm ntawm qhov ncauj hypoglycemic tshuaj thiab kev teem sijhawm kho tshuaj insulin. Thaum kho, kev saib xyuas lub raum kev ua haujlwm yog qhov tsim nyog; kev txiav txim siab ntawm ntshav plasma lactate yuav tsum tau ua tsawg kawg 2 zaug hauv ib xyoos, nrog rau qhov pom ntawm myalgia. Kev tsim kho ntawm cov kab mob lactic acidosis yuav tsum tsis ua ntxiv mus ntawm kev kho mob.

48 teev ua ntej kev phais mob lossis kev tso dej ntawm lub cev iodine-muaj radiopaque tus neeg sawv cev, Glimecomb® yuav tsum tau txiav tawm, kev kho yog pom zoo kom rov ua dua tom qab 48 teev.

Tawm tsam keeb kwm ntawm kev kho nrog Glimecomb®, tus neeg mob yuav tsum tso tseg txoj kev haus cawv thiab / lossis cov tshuaj uas muaj cawv thiab tshuaj noj.

Thaum lub sijhawm kho mob, yuav tsum tau saib xyuas thaum tsav tsheb thiab koom nrog lwm yam kev phom sij uas yuav tsum muaj kev mloog zoo thiab ceev ntawm cov kev tiv thaiv psychomotor.

Cov lus qhia rau kev teem caij

Sulfonylurea derivatives (PSM) yog cov tshuaj ntau tshaj 2 rau cov neeg mob ntshav qab zib tom qab metformin. Kev sib xyaw ntawm PSM thiab metformin yog qhov yuav tsum tau ua rau cov neeg mob uas tsis pub noj cov zaub mov tsis zoo, kev ua kis las, thiab metformin tsis muab qhov xav txo qis qab zib. Cov tshuaj no ua rau cov kab mob tseem ceeb ntawm kev sib txuas ntawm cov ntshav qab zib tsim hom 2: tiv thaiv insulin siab thiab insulin tsis txaus, yog li lawv muab cov txiaj ntsig zoo tshaj plaws rau kev sib xyaw. Glyclazide, ib qho tshuaj ntawm Glimecomb, yog PSM ntawm 2 tiam thiab suav hais tias yog ib qho kev nyab xeeb tshaj plaws hauv nws pawg.

Glimecomb ntsiav tshuaj tuaj yeem muab tshuaj:

1. Thaum cov kev kho mob tas los tsis tseg muab cov nyiaj zoo rau cov ntshav qab zib.
2. Tam sim ntawd tom qab kuaj mob ntshav qab zib, yog tias qib ntawm glycemia yog siab heev.
3. Yog hais tias tus mob ntshav qab zib tsis zam metformin ntau hauv qhov ntau.
4. Txhawm rau txo cov ntsiav tshuaj ntau hauv cov neeg mob noj gliclazide thiab metformin.
5. Tus mob ntshav qab zib nyob rau hauv leej twg glibenclamide (Maninil thiab analogues) lossis nws cov tshuaj ua ke nrog metformin (Glibomet thiab lwm tus) ua rau muaj ntshav ntau heev los yog tsis paub txog tias muaj ntshav qab zib tsawg.
6. Cov neeg mob uas lub raum tsis ua haujlwm rau leej twg glibenclamide raug txwv.
7. Ntshav qab zib uas nyuaj los ntawm kab mob plawv. Gliclazide tsis tau pom muaj qhov tsis zoo ntawm myocardium.

Raws li kev tshawb nrhiav, twb tau ib hlis ntawm kev kho mob nrog Glimecomb, yoo cov piam thaj txo qis los ntawm qhov nruab nrab ntawm 1.8 mmol / L.Nrog txuas ntxiv siv cov tshuaj, nws cov nyhuv ua rau muaj zog, tom qab 3 lub hlis txo yog twb 2.9. Peb lub hlis kho cov dej qab zib ib txwm nyob hauv ib nrab ntawm cov neeg mob uas mob ntshav qab zib mellitus, thaum koob tsis ntau tshaj 4 ntsiav tshuaj ib hnub. Qhov hnyav nce thiab mob ntshav qab zib heev, uas yuav tsum tau mus pw hauv tsev kho mob, tsis tau sau nrog cov tshuaj no.

Cov Tshuaj Kho Mob Glimecomb

Kev sib xyaw ntawm PSM thiab metformin yog suav tias yog tshuaj lom neeg. Txawm hais tias muaj qhov tshwm sim ntawm cov kab mob ntshav qab zib tshiab, lub koom haum koom tes mob ntshav qab zib thoob ntiaj teb thiab Ministry of Health ntawm Lavxias tseem txuas ntxiv pom zoo rau kev sib xyaw ua ke no uas yog qhov muaj peev xwm tshaj plaws. Glimecomb yog qhov yooj yim rau kev siv thiab pheej yig. Nws cov khoom siv ob qho tib si nkaus thiab muaj kev nyab xeeb.

Glyclazide nrog cov ntshav qab zib hom 2 txhawb kev tsim tawm ntawm nws tus kheej insulin, thiab pib ua haujlwm hauv thawj theem ntawm nws qhov kev tso tawm, thaum suab thaj nyuam qhuav nkag mus rau hauv cov hlab ntshav. Qhov kev ua no tso cai rau koj kom sai glycemia tom qab noj mov, xa cov piam thaj rau cov ntaub so ntswg. Glyclazide tiv thaiv kev txhim kho angiopathy: tiv thaiv thrombosis, txhim kho microcirculation thiab lub xeev ntawm cov phab ntsa ntawm cov hlab ntsha. Qhov ua tau zoo ntawm gliclazide ntawm chav kawm ntawm retinopathy thiab nephropathy tau ua pov thawj. Siv tshuaj ntsiav kab mob Glimecomb tsis ua rau muaj cov tshuaj insulin ntxiv rau hauv cov ntshav, yog li lawv tsis ua kom yuag. Cov lus qhia kuj tau sau tseg lub peev xwm ntawm gliclazide los txhim kho insulin rhiab heev, tab sis qhov no nws tseem nyob deb ntawm metformin, ib tus thawj coj lees paub hauv kev tawm tsam insulin tsis kam.

Metformin yog ib yam tshuaj nkaus xwb pom zoo rau txhua tus mob ntshav qab zib hom 2 yam tsis suav daws. Nws stimulates kev hloov ntawm cov piam thaj los ntawm cov hlab ntshav mus rau cov hlwb, inhibits kev tsim cov piam thaj los ntawm lub siab, ncua nws qhov kev nqus ntawm cov hnyuv. Cov tshuaj ua tiav rau cov lipid metabolism tsis zoo, uas yog tus yam ntxwv rau hom 2 ntawm tus kabmob. Vim muaj ntau cov kev soj ntsuam zoo ntawm cov ntshav qab zib, metformin yog siv rau cov neeg poob phaus. Nws tsis ua rau kev mob ntshav qab zib, thaum siv raws li cov lus qhia ua haujlwm tag. Qhov tsis zoo ntawm qhov kev tivthaiv ntawm Glimecomb no yog qhov muaj ntau ntawm qhov tsis xav tau ntawm lub plab zom mov.

Pharmacokinetics ntawm cov tshuaj tiv thaiv:

2 teev thaum thov rau ntawm lub plab tas

2.5 teev yog tias koj noj tshuaj tib lub sijhawm nrog zaub mov, raws li cov lus qhia.

Cov tshuaj Glimecomb muaj ib qho kev xaiv tshuaj ntau npaum li cas - 40 + 500, hauv ib ntsiav tshuaj 40 mg ntawm glyclazide, 500 mg ntawm metformin. Txhawm rau kom tau txais ib nrab koob, cov ntsiav tshuaj tuaj yeem faib, muaj kev pheej hmoo ntawm nws.

Yog tias cov ntshav qab zib tsis tau noj cov tshuaj metformin ua ntej, 1 ntsiav tshuaj yog suav tias yog pib siv tshuaj. Tom ntej 2 lub lis piam nws tsis tsim nyog ua kom nws nce ntxiv, yog li koj tuaj yeem txo qhov kev pheej hmoo ntawm qhov tsis xis nyob hauv cov hnyuv. Cov neeg mob uas tau paub txog cov tshuaj metformin thiab tiv thaiv nws zoo yuav tuaj yeem kho tam sim ntawd txog 3 Glimecomb ntsiav tshuaj. Cov koob tshuaj ntau yam tau txiav txim siab los ntawm tus kws kho mob, coj mus rau hauv tus neeg mob qib glycemia thiab lwm yam tshuaj uas nws noj.

Yog hais tias qhov pib noj tshuaj tsis muab cov nyhuv yam xav tau, nws yog maj mam nce ntxiv. Txhawm rau txhawm rau tiv thaiv hypoglycemia, lub sijhawm nruab nrab ntawm kev hloov kho tshuaj yuav tsum yog tsawg kawg ib lub lim tiam. Qhov siab pub ntau tshaj yog 5 ntsiav tshuaj. Yog tias nyob ntawm qhov tshuaj no, Glimecomb tsis them nyiaj rau cov ntshav qab zib mellitus, lwm qhov kev txiav txim siab rau cov ntshav qab zib tau raug txiav txim rau tus neeg mob.

Yog tias tus neeg mob tau txais tshuaj tiv thaiv kab mob siab tshaj plaws, Glimecomb hauv ntshav qab zib tuaj yeem yuav haus cawv nrog metformin. Tus naj npawb ntawm cov ntsiav tshuaj nyob rau hauv cov ntaub ntawv no tau suav kom meej tag nrho cov koob tshuaj metformin tsis pub dhau 3000 mg.

Cov kev cai rau noj cov tshuaj Glimecomb

Txhawm rau txhim kho kev zam ntawm metformin thiab tiv thaiv kom tsis txhob muaj cov piam thaj hauv qab zib, Glimecomb ntsiav tshuaj tau qaug cawv ib txhij nrog zaub mov lossis tam sim ntawd. Cov zaub mov yuav tsum ua kom zoo thiab yuav tsum muaj cov carbohydrates, dua li nyuaj rau kev zom. Kev txiav txim los ntawm kev txheeb xyuas, nce txog 15% ntawm cov neeg mob ntshav qab zib ntseeg tau hais tias kev noj Glimecomb thiab lwm yam tshuaj txaws txo kev noj qab haus huv ua rau lawv qhov kev xav tau ua raws li kev noj zaub mov noj. Raws li qhov tshwm sim, lawv noj ntau dua cov tshuaj ntau dua, uas ua rau lawv cov kev mob tshwm sim ntau dua thiab cov nqi kho mob, yws txog cov piam thaj ntawm cov piam thaj, thiab ua rau lub ntsej muag mob ntshav qab zib ua ntej.

Tam sim no tsis yog ib hom tshuaj kho mob ntshav qab zib rau ntshav qab zib tuaj yeem hloov cov zaub mov noj. Nrog rau hom kab mob 2, khoom noj khoom haus yog pom tias tsis muaj cov carbohydrates ceev, nrog kev txwv ntawm cov carbohydrates qeeb, thiab feem ntau nrog cov zaub mov tsis muaj calorie tsawg - cov khoom noj rau cov ntshav qab zib hom 2. Cov kev kho mob yuav suav nrog qhov hnyav li qub thiab hnyav ntxiv.

Txhawm rau kom paub tseeb tias kev coj ua ntawm Glimecomb thaum nruab hnub, noj ntau npaum li cas tau muab faib ua 2 koob tshuaj - thaum sawv ntxov thiab yav tsaus ntuj. Raws li kev tshuaj xyuas, cov txiaj ntsig kho tau zoo tshaj plaws raug pom nyob hauv cov neeg mob uas noj tshuaj peb zaug (tom qab noj mov tas), txawm hais tias cov lus qhia rau kev siv tsis muaj rau qhov kev xaiv ntawd.

Tus kws kho mob ntawm Kev Tshawb Fawb Kev Kho Mob, Lub Taub Hau ntawm lub koom haum ntawm Diabetology - Tatyana Yakovleva

Kuv tau kawm mob ntshav qab zib tau ntau xyoo. Nws yog txaus ntshai thaum muaj coob tus neeg tuag, thiab haj yam ua rau neeg xiam vim ntshav qab zib.

Kuv maj nrawm los qhia txoj xov zoo - Endocrinological qhov chaw tshawb fawb ntawm Lavxias Academy ntawm Medical Science tau tswj hwm los tsim cov tshuaj uas kho cov mob ntshav qab zib mellitus kom zoo. Thaum lub sijhawm, cov hauj lwm zoo ntawm cov tshuaj no tau nce mus txog 98%.

Lwm qhov xov xwm zoo: Lub Tsev Haujlwm Saib Xyuas Kev Noj Qab Haus Huv tau txais kev nyab xeeb qhov kev saws me nyuam ntawm cov haujlwm tshwj xeeb uas them rau cov nqi tshuaj ntau. Hauv Lavxias, neeg mob ntshav qab zib kom txog thaum lub Tsib Hlis 18 (suav nrog) tuaj yeem tau txais nws - Tsuas yog 147 rubles!

Sab sij huam

Feem ntau ntawm cov kev mob tshwm sim tuaj yeem ua kom tsis muaj zog yog tias koj ua raws li txoj cai rau kev noj thiab nce qhov koob tshuaj los ntawm cov lus qhia. Kev tshem tawm ntawm Glimecomb vim qhov tsis zwm rau yog tsis tshua muaj.

Cov Yuav Tsum Muaj

Thaum koj tsis tuaj yeem haus dej haus Glimecomb:

• ntshav qab zib hom 1
• ntshav qog. Cov tshuaj tsis tuaj yeem quav kom txog thaum cov ntshav qab zib nce siab kom ib txwm,
• mob ntshav qab zib tsis txaus, mob hnyav thiab raug mob uas yuav tsum tau kho tshuaj insulin. Ib kis ntawm lactic acidosis yav dhau los,
• muaj menyuam hauv plab, pub niam mis,
• Xoo hluav taws xob nrog iodine-muaj cov neeg sawv cev sib piv
• intolerance rau ib qho ntawm cov tshuaj ntawm cov tshuaj,
• lub raum, lub siab ua haujlwm, hypoxia, thiab cov kab mob uas yuav ua rau muaj kev cuam tshuam,
• kev haus dej cawv, haus cawv ntau zaug.

Hauv cov neeg mob uas muaj cov kabmob hormonal, cov laus ntshav qab zib nrog lub zog ntev dhau los, qhov kev pheej hmoo ntawm kev phiv yog nce, yog li thaum noj Glimecomb, lawv yuav tsum tau ceev faj tshwj xeeb txog lawv kev noj qab haus huv.

Sib xyaw nrog lwm yam tshuaj

Qhov cuam tshuam ntawm glimecomb tej zaum yuav ntxiv dag zog lossis qaug zog thaum noj nrog lwm cov tshuaj. Cov npe ntawm kev sib txuam nrog tshuaj yog qhov loj heev, tab sis feem ntau qhov kev hloov pauv ntawm qhov tsis muaj txiaj ntsig tsis yog qhov tseem ceeb thiab tuaj yeem hloov kho tau yooj yim los ntawm kev hloov ntau npaum li cas.

Dab tsi analogues los hloov

Glimecomb tsis muaj tag nrho cov analogues tso npe ntawm Lavxias Federation. Yog tias cov tshuaj tsis nyob hauv tsev muag tshuaj, ob lub tshuaj nrog tib lub tshuaj muaj peev xwm hloov nws:

1. Metformin muaj nyob hauv thawj Glucofage tsim nyob rau hauv Fabkis, German Siofor, Lavxias Metformin, Merifatin, Gliformin. Txhua tus muaj tshuaj ntau npaum 500 mg. Rau cov neeg mob ntshav qab zib nrog kev tsis txaus siab ntawm metformin, ib daim ntawv hloov pauv ntawm cov tshuaj yog qhov zoo dua, uas ua kom ntseeg tau tias kev nkag mus ntawm cov tshuaj mus rau hauv cov ntshav thiab txo qhov kev pheej hmoo ntawm phiv. Cov no yog cov tshuaj Metformin Ntev Canon, Metformin MV, Formin Ntev thiab lwm yam.
2. Gliclazide kuj tseem yog cov hypoglycemic heev. Cov tshuaj yog ib feem ntawm Lavxias Glidiab thiab Diabefarm. Modic Gliclazide tam sim no tau txiav txim siab daim ntawv nyiam. Nws siv tau tuaj yeem txo cov zaus thiab mob hnyav ntawm cov qog ntshav qab zib. Modic gliclazide muaj nyob hauv kev npaj Diabefarm MV, Diabeton MV, Gliclazide MV, Diabetalong, etc. Thaum muas, koj yuav tsum them sai sai rau qhov tshuaj, koj yuav tsum faib cov ntsiav tshuaj ib nrab.

Muaj ntau ntau pab pawg analogues ntawm Glimecomb ntawm kev ua lag luam Lavxias. Feem ntau ntawm lawv yog kev sib xyaw ntawm metformin nrog glibenclamide. Cov tshuaj no tsis muaj kev nyab xeeb dua li glimecomb, vim tias lawv feem ntau ua rau lub cev tsis muaj ntshav qab zib. Ib qho kev hloov zoo rau Glimecomb yog Amaryl (metformin + glimepiride). Tam sim no, nws yog qhov ua tau zoo tshaj plaws ob qho tshuaj yeeb nrog PSM.

Tus nqi ntawm ib pob ntawm 60 ntsiav tshuaj ntawm Glimecomb yog los ntawm 459 txog 543 rubles. Gliclazide thiab metformin los ntawm tib lub tuam txhab tsim tawm yuav raug nqi 187 rubles. rau tib lub koob tshuaj (60 ntsiav tshuaj ntawm Glidiab 80 mg nqi 130 rubles, 60 ntsiav tshuaj. Gliformin 500 mg - 122 rubles). Tus nqi ntawm kev sib koom ua ke ntawm qhov kev npaj qub ntawm gliclazide thiab metformin (Glucofage + Diabeton) yog kwv yees li 750 rubles, ob qho tib si nyob rau hauv daim ntawv hloov kho.

ISSUE FORM

Ntsiav tshuaj 40 mg + 500 mg. Txog 30, 60 lossis 120 ntsiav tshuaj hauv lub raj mis rau tshuaj ua los ntawm cov yas. On 10 lossis 20 ntsiav tshuaj nyob rau hauv lub blister sawb ntim. Ib lub raj mis los yog 6 blister pob ntawm 10 ntsiav tshuaj, lossis 5 blister pob ntawm 20 ntsiav tshuaj txhua nrog rau cov lus qhia rau kev siv hauv cov ntawv ntim ntawm cardboard.

Cov ntaub ntawv dav dav

Glimecomb yog kev sib koom ua ke rau kev kho mob ntshav qab zib hom 2. Nws ob lub ntsiab lus tseem ceeb yog metformin thiab gliclazide. Thawj cov tshuaj cuam tshuam nrog biguanides, qhov thib ob yog sulfonylurea derivative.

Nws qhov txawv ua ke ntawm kev sib txuas ntawm ob qhov nrov tshaj plaws thiab muaj txiaj ntsig. Qhov tseem ceeb tau txais txiaj ntsig dua lwm cov tshuaj sib xyaw ua ke yog qhov tsawg kawg nkaus ntawm kev txo qis ntshav qab zib. Nws yog tsim los ntawm cov tuam txhab tshuaj Lavxias teb sab Akrikhin.

Kev ntsuas rau siv

Cov tshuaj yog npaj rau cov neeg mob ntshav qab zib hom 2. Ua ntej, cov kws kho mob hais qhia kev noj zaub mov noj, nrog rau ib ce ntawm lub cev niaj hnub. Yog tias, tom qab qee lub sijhawm, cov kev ntsuas no tsis coj ua tiav qhov kev cia siab, qhov kev kho mob ntxiv nrog rau tshuaj. Yuav pib nrog, tus neeg mob tau sau tshuaj ib qho tshuaj sib tshooj raws li metformin. Yog hais tias kho qhov mob tshwm sim tsis tshwm sim, kev sib txuas ua ke yog qhia.

Daim ntawv tso tawm

“Glimecomb” yog ib cov tshuaj qab zib-dawb uas muaj lub cim zoo, zoo li tiaj. Qauv Marble tso cai. Muaj ib qho kev pheej hmoo diametrical. Cov ntsiav tshuaj tau ntim rau hauv thawv ntawm 30 lossis 60 daim.

Tus nqi kwv yees ntawm pob 30 pcs ntawm “Glimecomba” hauv cov khw muag tshuaj Lavxias yog los ntawm 276 rubles.

Kwv yees tus nqi hauv kev ntim 60 pcs - los ntawm 524 rubles.

Txhua ntsiav tshuaj muaj 500 mg ntawm metformin thiab 40 g ntawm gliclazide. Cov no yog ob qho khoom xyaw tseem ceeb. Nws yog cov cim no uas txiav txim siab nws cov kev ua haujlwm siab, nrog rau cov "mos" ntawm kev nqis tes ua.

Kev tsim kho hauv ntshav qab zib - tsuas yog haus txhua txhua hnub.

Ntawm cov pawg neeg tseem ceeb: sorbitol, povidone, magnesium stearate, croscarmellose sodium.

Vim tias tsis muaj lactose, cov tshuaj tau tso cai siv rau hauv cov neeg nrog nws tsis nkag siab.

Cov lus qhia rau kev siv

Glimecomb ntsiav tshuaj yog npaj rau qhov ncauj siv lub sijhawm los yog tom qab noj mov tas. Nws nyob ntawm qhov loj npaum li cas ntawm cov koob tshuaj thiab qhov mob ntawm lub plab zom mov ntawm tus neeg mob. Thaum txoj kev kho, nws yog ib qho tsim nyog yuav tsum ua raws nraim li cov cai ntawm kev noj zaub mov kom tsawg. Raws li cov cai no, tsis muaj ib yam dab tsi yuav tsum koj hla pluas tshais.

Lub cev nqaij daim tawv ntawm tus neeg mob, nrog rau nws lub hlwb-kev xav hauv lub xeev, tau muaj qhov cuam tshuam zoo ntawm kev muab tshuaj. Kev tshaib kev nqhis, txawm hais tias luv luv, thiab tshwj xeeb tshaj yog haus dej cawv, tsis pub.

Kev ntim khoom yuav tsum muab khaws cia rau hauv qhov chaw tsaus thaum kub txog 25 ° C. Ua ntej yuav khoom, nws yog qhov zoo dua rau kev them nqi rau hnub ua khoom noj thiab hnub tas sij hawm. Cov tshuaj uas muaj hnub tas sij hawm uas tau nyob ze qhov kawg nws zoo dua tsis tas yuav khoom.

Daim ntawv thov nta

Vim tias qhov kev pheej hmoo siab ntawm kev tsim mob lactic acidosis, Glimecomb tsis pom zoo rau cov neeg laus dua 60 xyoo, thiab rau cov neeg mob ua lub cev hnyav.

Cev xeeb tub yog ib qho tseeb contraindication rau nws siv. Yog li ntawd, thaum lub sijhawm nqa tus menyuam, nrog rau lub sijhawm npaj rau kev xeeb tub, nws yuav tsum tau hloov nrog lwm cov tshuaj.

Mis niam tsis sib haum nrog Glimecomb. Hauv qhov no, tus niam laus muaj ib qho kev xaiv: yog kev ua tiav lactation thiab hloov mus rau kev pub mis, lossis hloov cov tshuaj nws tus kheej.

Siv nrog ceev faj yog ua tau rau cov neeg mob ntawm cov kab mob ntawm endocrine system.

Peb muab cov luv nqi rau cov nyeem ntawm peb lub xaib!

Glimecomb txoj kev kho yog pub rau cov neeg mob ntshav qab zib uas ua raws li txhua qhov xav tau ntawm kev noj zaub mov kom tsawg. Noj mov yuav tsum ua ntu zus. Qhov khoob loj ntawm cov zaub mov tuaj yeem ua rau cov ntshav qabzib poob ntau dua. Tsis tas li ntawd, kev mob ntshav nce siab sai sai tuaj yeem ua rau kom haus dej haus cawv txawm tias muaj tsawg, nrog rau cov tshuaj tsis muaj tshuaj tiv thaiv kev tsis haum tshuaj.

Kev cuam tshuam nrog lwm yam tshuaj

Cov txiaj ntsig kho ntawm Glimecomb tuaj yeem ua kom muaj zog thiab ua kom tsis muaj zog los ntawm lwm cov tshuaj. Feem ntau, cov nyhuv no tsis cuam tshuam thiab yog tshem tawm los ntawm kev kho me me rau kev kho me me.

Tshuaj uas txo qhov hypoglycemic muaj peev xwm ntawm Glimecomb:

• steroidal tshuaj tiv thaiv,
• tej tshuaj hormonal, suav nrog kev txwv tsis pub,
• tshuaj kho mob
• tshuaj muaj nicotinic acid,
• tshuaj tiv thaiv kab mob.

Cov tshuaj uas txhim kho glycemic muaj peev xwm:

• antimicrobials
• Vitamin B6
• tshuaj non-tshuaj los tiv thaiv kev tiv thaiv,
• lwm yam tshuaj uas txo cov ntshav qab zib, suav nrog cov tshuaj insulin.

Txawm li cas los xij, tsuas yog tus kws kho mob koom nrog tuaj yeem kho qhov koob tshuaj ntawm Glimecomb. Tus neeg mob tsuas yog yuav tsum tau ceeb toom nws kom raws sij hawm txog cov tshuaj uas nws noj lossis npaj yuav noj.

Sab sij huam

Glimecomb muaj cov npe loj ntawm cov kev mob tshwm sim. Txhawm rau kom txo lawv cov txiaj ntsig ntawm lub cev, nws yog ib qho tsim nyog yuav tsum ua raws nruj kev cai txais tos cov kev cai teev rau hauv cov lus qhia.

Glimecomb tau zoo zam txim. Nws txoj kev tshem tawm vim kev nkag tsis tau yog qhov tsis tshua muaj.

Pharmacokinetics ntawm cov khoom siv tshuaj ntsuab

Cov tshuaj no yog cim los ntawm muaj cov txiav txim siab thiab ntxiv cov nyhuv ntxiv.

Gliclazide stimulates kev tsim cov tshuaj insulin los ntawm beta hlwb ntawm cov txiav thiab pab ntxiv qhov rhiab ntawm insulin-ua rau cov nqaij mos ua kom lub cev tsim cov tshuaj insulin. Tsis tas li ntawd, qhov sib txuas ua ke pab tsim kho qhov mob rau cov leeg nqaij - leeg mob glycogen synthetase. Kev siv cov gliclazide pab kom rov ua tiav thaum kawg ntawm cov tshuaj tiv thaiv insulin thiab txo qis postpradial hyperglycemia.

Ntxiv rau qhov muaj feem cuam tshuam rau cov txheej txheem ntawm cov pluas mov carbohydrate, kev siv ntawm qhov kev sib xyaw no cuam tshuam rau cov ntshav microcirculation, txo cov qib ntawm kev nplaum thiab kev sib sau ua ke ntawm cov platelets, ua rau qeeb ntawm kev hloov kho ntawm parietal thrombosis, rov qab lub cev permeability ntawm cov vascular phab ntsa, txo cov lus teb ntawm cov leeg ntshav phab ntsa rau adrenaline thaum microangiopathy.

Kev siv cov gliclazide pab ua rau qeeb kev loj hlob ntawm cov ntshav qabzib retinopathy; tsis tas li ntawd, nyob rau hauv muaj nephropathy, tau pom tias muaj proteinuria tsawg dua.

Metformin yog qhov sib xyaw tshuaj lom neeg koom nrog cov pab pawg biguanide. Cov compound no pab txo cov piam thaj hauv cov ntshav ntshav. Qhov ua tau tiav los ntawm kev ua kom cov txheej txheem ntawm gluconeogenesis nyob rau hauv lub siab ua haujlwm, nrog rau kev txo qis ntawm kev nqus ntawm cov piam thaj los ntawm qhov lumen ntawm lub plab hnyuv, kuj los ntawm kev txhim kho kev nqus ntawm cov piam thaj los ntawm cov kab mob ntawm lub cev. Kev siv cov metformin pab txo qis cov roj triglycerides, cov roj (cholesterol) thiab cov lipoproteins uas tsis muaj ntau. Cov lus qhia ntawm metformin rau hauv lub cev muab qhov txo qis thiab ua kom lub cev nyhav.

Kev siv cov metformin thaum tsis txaus siv cov tshuaj insulin hauv cov ntshav tsis ua rau qhov tshwm sim ntawm kev kho mob thiab qhov tshwm sim ntawm hypoglycemic tshua tsis pom. Kev siv cov metformin kho txhim kho cov khoom fibrinolytic ntawm cov ntshav.

Qhov no yog ua tiav los ntawm kev ua kom tsis pub ib lub cev-hom activator inhibitor.

Kev taw qhia thiab contraindications rau kev siv ntawm cov tshuaj

Cov ntsiab lus rau kev siv Glimecomb yog hom 2 mob ntshav qab zib mellitus thaum tsis muaj kev ua tau zoo ntawm kev siv kev noj haus thiab kev siv lub cev, nrog rau thaum tsis muaj kev cuam tshuam ntawm kev kho mob yav dhau los nrog metaformine thiab glycazide.

Glimecomb yog siv los hloov cov kev kho ua dhau los ua txoj kev kho nrog ob Metformin thiab Glycoside npaj, muab tias cov ntshav qab zib cov ntshav nyob ruaj khov thiab tswj tau zoo.

Glimecomb muaj tag nrho ntau yam kev cuam tshuam rau kev siv tshuaj.

Lub ntsiab ntawm cov contraindications yog cov hauv qab no:

1. Kev ua haujlwm tsis txaus ntseeg ntawm tus neeg mob lub cev rau qhov tshwm sim ntawm metformin, gliclazide lossis lwm yam sulfonylureas. Ntxiv rau, cov tshuaj yuav tsum tsis txhob siv nyob rau hauv lub xub ntiag ntawm hypersensitivity rau lub cheeb tsam ntxiv ntawm cov tshuaj.
2. Muaj cov ntshav qab zib hom 1.
3. Lub xub ntiag ntawm cov kab mob ntshav qab zib ketoacidosis, mob ntshav qab zib precoma thiab coma hypoglycemic txheej xwm.
4. Kev tsim kho ntawm lub raum ua rau mob tsis zoo.
5. Kev tsim cov mob uas tuaj yeem ua rau hloov pauv ntawm lub raum kev ua haujlwm, kev txhim kho lub cev qhuav dej, ua mob hnyav thiab poob siab.
6. Kev txhim kho ntawm cov mob ntsws thiab mob ntev, nrog los ntawm tshwm sim ntawm cov nqaij mos hypoxia.
7. Qhov tshwm sim ntawm raum tsis ua haujlwm.
8. Porphyria.
9. Lub caij nyoog ntawm kev xeeb tub thiab lub sijhawm pub mis.
10. Ib txhij tswj hwm ntawm miconazole.
11. Cov kab mob sib kis thiab kev phais mob, kev kub nyhiab thiab qhov kev raug mob loj, uas thaum lub sijhawm kawm kho yuav tsum siv tshuaj insulin.
12. Lub xub ntiag ntawm cov kev quav dej cawv mus ntev thiab mob qaug cawv kom qaug cawv.
13. Kev tsim cov kab mob lactic acidosis.
14. Ua raws li cov zaub mov noj muaj carb tsawg.

Ntxiv rau cov rooj plaub no, cov tshuaj txwv tsis pub siv thaum siv rau kev tshuaj xyuas lub cev iodine-muaj qhov zoo sib xws.

Tsis txhob siv cov tshuaj rau kev kho mob ntshav qab zib rau cov neeg mob uas tau mus txog hnub nyoog 60 xyoo, uas tau ntsib kev mob lub cev ntau dhau. Qhov no yog vim muaj qhov tshwm sim siab ntawm kev txhim kho cov mob lactic acidosis hauv cov neeg mob ntawd.

Tshwj xeeb yuav tsum ceev faj thaum noj tshuaj yog tias tus neeg mob tau ua cim febrile, tsis txaus ntseeg kev ua haujlwm ntawm lub qog adrenal, qhov ntau ntawm qhov tsis ua haujlwm ntawm lub caj pas anterior pituitary, lub qog mob, uas ua rau muaj kev ua txhaum ntawm nws txoj haujlwm.

Kev siv yeeb tshuaj

Cov lus qhia rau kev siv Glimecomba tswj hwm thiab piav qhia txhua yam nyob rau hauv uas nws pom zoo kom noj cov tshuaj thiab thaum siv cov tshuaj txwv tsis pub. Cov lus qhia tau hais txog txhua yam kev phiv uas tshwm sim thaum siv cov khoom lag luam thiab cov tshuaj pom zoo rau siv.

Cov tshuaj yog siv qhov ncauj thaum noj mov lossis tom qab kiag. Cov koob tshuaj uas tsim nyog rau kev nkag mus yog txiav txim los ntawm tus kws kho mob mus kawm raws li cov txiaj ntsig ntawm kev tshuaj ntsuam thiab tus yam ntxwv ntawm tus neeg mob lub cev. Cov koob tshuaj ntawm cov tshuaj tau txiav txim siab raws li theem ntawm cov piam thaj hauv cov neeg mob lub cev.

Feem ntau, kev txhaj tshuaj thawj zaug pom zoo los ntawm tus kws kho mob rau tus neeg mob yog 1-3 ntsiav tshuaj ib hnub nrog kev maj mam xaiv cov tshuaj txhawm rau muab cov tshuaj tiv thaiv ntshav qab zib kom ruaj khov. Yog tias koj tsis ua raws li cov lus pom zoo, tom qab ntawd ua rau cov ntshav qab zib muaj zog yuav tshwm sim.

Feem ntau, cov tshuaj yuav tsum noj ib hnub ob zaug thaum sawv ntxov thiab yav tsaus ntuj. Thiab kev noj tshuaj ntau tshaj plaws tuaj yeem yog 5 ntsiav tshuaj.

Muaj cov lus qhia tshwj xeeb uas yuav tsum tau ua thaum coj ua Kev Kho Mob Glimecomb:

• kev kho yuav tsum tau nqa tawm tsuas yog ua ke nrog kev noj zaub mov kom tsis txhob muaj calorie tsawg tsawg uas muaj cov carbohydrates,
• cov neeg mob yuav tsum tau txais cov zaub mov tsis muaj txiaj ntsig, uas yuav tsum tau muaj xws li noj tshais,
• Yuav kom zam tau txoj kev txhim kho cov tsos mob ntawm tus mob ntshav qab zib tsawg, yuav tsum xaiv cov tshuaj ntau npaum li cas,
• thaum kev ua haujlwm ntawm lub cev thiab kev ntxhov siab ntau dhau ntawm lub cev, kev hloov kho tshuaj yuav tsum tau noj, yuav tsum tau kho.

Thaum coj kev kho mob nrog cov tshuaj xws li Glimecomb, koj yuav tsum tsis kam lees haus dej haus cawv thiab cov khoom noj uas muaj cov tshuaj cawv hauv lawv cov qauv.

Tshwj xeeb yuav tsum ceev faj thaum siv cov tshuaj thaum koom nrog cov kev ua haujlwm uas yuav tsum muaj kev kub siab ntawm kev saib xyuas thiab ceev ntawm cov tshuaj tiv thaiv.

Muaj kev phiv ntau

Thaum noj cov tshuaj, tus neeg mob yuav ntsib teeb meem ntau yam tshwm sim.

Hauv cov txheej txheem hauv lub cev hauv lub cev, qhov ua txhaum ntawm kev noj ntau npaum li cas lossis thaum siv cov khoom noj tsis zoo, kev tsis haum xeeb tuaj yeem txhim kho uas ua rau lub cev tsis muaj ntshav qab zib. Qhov xwm txheej ntawm lub cev no yog nrog mob taub hau, qhov tshwm sim zoo li qaug zog, lub zog muaj kev xav ua kom muaj kev tshaib plab, lub plawv dhia, qhov tsos ntawm kiv taub hau, thiab ua tsis tau zoo ntawm kev txav.

Tsis tas li ntawd, yog tias kev noj tshuaj ntau dua nyob rau hauv tus neeg mob, lub xeev ntawm cov kab mob lactic acidosis yuav tshwm sim, tshwm sim los ntawm qhov tsis muaj zog myalgia, tsaug zog ntxiv, mob plab thiab txo ntshav siab.

Cov kev tsis zoo hauv qab no tuaj yeem tshwm sim hauv lub plab zom mov:

1. zoo nkaus li xeev siab
2. kev txhim kho mob raws plab,
3. cov tsos ntawm kev xav ntawm hnyav nyob rau hauv lub epigastrium,
4. cov tsos ntawm saj ntawm cov hlau hauv lub qhov ncauj,
5. tsis qab los
6. Hauv qee qhov tsis tshua muaj tshwm sim, daim siab puas xws li mob siab, mob cholestatic jaundice thiab qee yam ntxiv tshwm sim.

Yog tias muaj kev txawv txav hauv lub siab, cov tshuaj yuav tsum nres tam sim ntawd.

Nyob rau hauv kev ua txhaum ntawm kev tsuas tshuaj thiab cov ntsiab cai ntawm kev kho, kev txhim kho ntawm kev tiv thaiv ntawm hematopoietic kev ua haujlwm tau muaj.

Raws li kev phiv, tus neeg mob tuaj yeem tsim kev phiv tshuaj, tshwm sim los ntawm qhov khaus, urticaria thiab maculopapular pob.

Yog hais tias tus neeg mob tsim muaj kev mob tshwm sim los ntawm kev noj tshuaj, koj yuav tsum txo qhov ntau npaum li cas tam sim ntawd lossis txiav kev siv tshuaj.