Dab tsi yog qhov zoo dua Omez lossis Pariet nrog pancreatitis?

Thiab ntawm no yog kuv txoj kev xav txog cov tshuaj no. Tag nrho cov PPIs tshem tawm 100% acid yog 40 mg noj. Thiab yog li xaiv lawv. Thiab tsis tshua muaj nyob hauv ib nrab koob. Tab sis txawm tias nyob hauv ib nrab koob tshuaj, lawv tsuas yog sai thiab tas mus li txo acidity, tsuas yog qee lub sijhawm. Thiab vim li cas kuv ntshai tias nws tau txaus ntshai los siv yeeb tshuaj zoo li no thiab, nws zoo li rau kuv, nws nchuav, yog tias muaj kev xav tau sai, koj tuaj yeem tso cov kua zaub muaj kab mob rau ntawm lub cev. Yog li ntawd, Kuv coj cov tshuaj muaj zog tsawg dua: famotidine, ranitidine. Lawv txaus ntshai rau TM, tias muaj kev rov tshwm sim thaum lub sijhawm tshem tawm, tab sis ntawm no ... nws yeej yog, thiab PPI tau hais tias nws tsis yog. Txawm yog li, tab sis tsis yog los ntawm rab phom loj ntawm tus po. Ib qho hauv kev kub ntxhov lossis chav kawm luv. Thiab yog tias kev tswj hwm acid feem ntau tsim nyog vim tias acidity ntau ntxiv?

Zoo, muaj txoj cai lij choj rau cov kws kho mob. Cov tshuaj yog xav tau, ceev ceev thiab chaw tsim tshuaj paus .. raws li nws tau .. khoom plig .. qhov no yog kuv lub tswv yim, nws yuav yuam kev. Tab sis kuv tsis xav tau lub zog ntawm cov kua qaub no, hos cov tshuaj tsis muaj zog pab tau.

Cov chaw muag tshuaj

Cov tshuaj muaj pes tsawg leeg ntawm Omez suav nrog cov tshuaj nquag omeprazole, uas txo cov kev tsim ntawm hydrochloric acid hauv plab thiab cuam tshuam tsis zoo rau Helicobacter, uas yog ib hom kab mob uas ua rau mob rwj plab. Cov tshuaj muaj txiaj ntsig thaum nruab hnub, nws cov bioavailability (degree ntawm assimilation) nrog ib zaug tsis siab tshaj 40%.
Cov tshuaj nquag nyob hauv Pariet yog rabeprazole. Nws kuj txwv tsis pub cov kua qaub tsim tawm los ntawm cov roj ntsha ntawm lub puab sab hauv ntawm lub plab, tab sis tsis cuam tshuam rau Helicobacter. Lub sijhawm sijhawm ntawm cov kev kho mob ntawm rabeprazole tuaj yeem ncav cuag li 2 hnub, thiab kev siv ua kom nyab xeeb yog 52%.

muaj qhov txhab thiab voos ntawm lub plab lossis duodenum, tsis hais lawv keeb kwm,
gastroesophageal reflux disease - GERD (kev puas tsuaj rau phab ntsa txoj hlab pas vim qhov cov kua qaub ua rau lub cev rov qab los ntawm lub plab),
Zollinger-Ellison syndrome - pancreatic neoplasm uas tso cov enzymes, uas tig tau tsim cov kua qaub,
kev mob plab hauv lub plab (gastritis), ua rau los ntawm pH tsawg qhov tseem ceeb ntawm lub plab zom mov,
kev tiv thaiv ntawm acid hlawv los ntawm lub plab ntawm lub ntsws ua pa (Mendelssohn syndrome),
cov tsos mob ntawm kev ua txhaum ntawm lub pais plab theem ntawm kev zom zaub mov - xeev siab, kub siab, khaus, mob.

mob pob txuv thiab mob ua rau lub plab ntawm lub plab lossis duodenum, suav nrog cov uas tshwm sim los ntawm helicobacter - ib yam kab mob uas ua rau mob siab kho,
mob rwj hauv plab ua hauj lwm,
GERD,
Zollinger-Ellison syndrome.

Cov Yuav Tsum Muaj

tus neeg tsis qaug rau yeeb tshuaj,
tib lub sij hawm siv ib tug naj npawb ntawm cov tshuaj npaj rau kev kho qog, fungal thiab kis mob,
cov menyuam yaus hnub nyoog qis dua 2 xyoos.

muaj lub cev tsis haum rau lub tshuaj,
lub sijhawm uas xeeb tub thiab pub niam mis,
cov me nyuam qis dua 12 xyoos.

Sab sij huam

ua xua
ntxhov siab thiab kev nyuaj siab, pw tsaug zog tsis meej,
tsis pom kev, hnov lus thiab saj zoo,
kiv tob hau, mob taub hau,
lus txhais
ua kom poob qis hauv kev mloog zoo ntawm txhua cov qe ntshav,
cuam tshuam ntawm daim siab,
dryness thiab mob hloov hauv lub qhov ncauj kab noj hniav,
mob plab, tso mob plab, ua pob,
xeev siab, ntuav,
mob hauv cov leeg thiab pob qij txha.

cov tsos mob ua xua
raws plab thiab quav tawv,
kom qhuav tawm ntawm lub qhov ncauj kab noj hniav,
dajntoo
mob plab, mob plab heev,
mob taub hau, kiv taub hau,
kev tsim cov ntshav cell ntau lawm,
o mis rau cov txiv neej,
mob hauv cov pob qij txha thiab cov leeg.

Tso daim ntawv thiab tus nqi

10 mg tsiav tshuaj, 10 pcs. - 77 rubles.,
lub kaus mom. 20 mg, 30 pcs. - 148 rub.,
lub kaus mom. 40 mg, 40 pcs. - 275 rub.,
soluble lyophilisate 40 mg, 1 lub raj mis - 164 rubles.,
Omez Insta, hmoov, 20 mg, 5 sachets - 80 rub.,
Omez DSR, lub kaus mom. 30 + 20 mg, 30 pcs. - 408 rub.,
Omez D, kaus mom. 10 + 10 mg, 30 pcs. - 322 rub.

10 mg ntsiav tshuaj, 14 pcs. - 1079 tshiav.,
tab. 10 mg, 7 pcs. - 986 rub.,
tab. 20 mg, 14 pcs. - 2049 rub.,
tab. 20 mg, 28 pcs. - 4047 rub.

Kev ntsuas rau siv

Pariet siv los kho:

reflux esophagitis,
benign plab mob,
duodenal mob rau sab hauv,
Zollinger-Ellison syndrome cuam tshuam nrog lub qog ntawm lub islet apparatus ntawm lub caj pas (txiav) zais zais ib qho kev hloov kho ntawm hydrochloric acid - gastrin,
mob caj dab ntev.

Ua ke nrog cov tshuaj tua kab mob, Pariet yog siv rau hauv kev tua kab mob (tua) los ntawm Helicobacter Pylori. Cov twj yog qhov tsim nyog rau kev kho mus sij hawm ntev hauv plab hnyuv plab zom mov.

Tsuas tshuaj thiab tswj hwm

Pariet tau tshuaj rau cov neeg laus nyob ntawm lawv lub cev kev mob ntawm lub cev. Cov chav kawm thiab ntau npaum li cas qhia hauv cov khw muag cov lus qhia muaj raws li hauv qab no:

Duodenal mob rwj thiab mob rwj hauv qhov nquag: 20 mg ib hnub ib zaug, thaum sawv ntxov. Lub chav kawm yog los ntawm 2 lub lis piam mus rau ib hlis.
Reflux esophagitis: 20 mg ib hnub ib zaug. Lub chav kawm yog 1-2 hlis.
Kev tshem tawm (kev tshem tawm) ntawm H. pylori: 20 mg ib hnub ob zaug rau ib lub limtiam nrog Clarithromycin thiab Amoxicillin.
Nrog rau daim ntawv muaj mob ntawm kev mob nqaij hlav ntawm tus txiav, Pariet (20 mg) tau sau tseg rau thaum sawv ntxov 30 feeb ua ntej noj tshais. Qhov kev kawm yog 4 lub lis piam. Tus kws kho mob tuaj yeem kho qhov ntau npaum li cas thiab lub sijhawm.

Noj tag nrho cov ntsiav tshuaj, tsis tas yuav zom, nrog rau cov dej huv txaus.

Pariet muaj cov khoom alkaline me ntsis. Hauv cov koob tshuaj raws cai, nws tau nrawm nrawm thiab pib ua hauv ib teev, khaws cia hauv parietal hlwb.

Sab sij huam

Cov kev mob tshwm sim thaum lub sijhawm tshawb fawb tau siv sijhawm luv luv thiab tau hais tawm raws li:

Hais txog 2% ntawm qhov xwm txheej ntawd yog mob: rhinitis, plob tsis ntxwm, mob pharyngitis, ntuav, mob nraub qaum, mob taub hau, cem quav, cem quav thiab pw tsis tsaug zog. Tsawg dua li 1% ntawm cov neeg mob noj Pariet yws yws ntawm myalgia, mob sib koom tes, qhov ncauj qhuav, tsaug zog, dyspepsia, txob taus, thiab lwm yam.

Muab qhov tsis zoo ntawm cov kev pom no, nws tau sau tseg tias Pariet tsis cuam tshuam rau kev tsav tsheb. Txawm li cas los xij, nrog kev qaug zog (ib qho tshwm sim), koj yuav tsum tsis txhob tsav tsheb thiab ua haujlwm nrog cov txheej txheem nyuaj.

Kev cuam tshuam nrog lwm yam tshuaj

Qhov kev tshuaj ntsuam kev sib xyaw ntawm rabeprazole sodium nrog Warfarin, Phenytoin, Theophylline, Diazepam tsis pom muaj kev sib cuam tshuam hauv chaw kho mob. Cov ntaub ntawv soj ntsuam cov ntaub ntawv qhia txog kev sib nrig sib rau ntawm Pariet thiab antacid npaj.

Tab sis nws txoj kev nqus tau cuam tshuam rau kev nqus ntawm vitamin B12, txo nws txoj kev nqus. Kev sib xyaw ntawm cov tshuaj nrog Ketoconazole lossis Itraconazole ua rau lawv cov ntsiab lus tsawg dua hauv cov ntshav plasma, thiab kev cuam tshuam nrog Digoxin, ntawm qhov tsis sib thooj, nce nws ntau hauv nws. Kev lees txais cov tshuaj no nrog Pariet yuav tsum tau ua nyob rau hauv kev saib xyuas ntawm tus kws kho mob tuaj koom.

Cov kws kho mob ceeb toom txog cov kev pheej hmoo ntawm kev siv tshuaj nrog cawv thiab haus cawv, vim tias qhov sib txuam nrog cawv ntawm rabeprazole sodium tsis tau kawm zoo.

Kev Sib Sau thiab daim ntawv ntawm kev tso tawm

Pariet pab txhawm rau ua kom lub zog ntawm cov enzyme (proton twj tso kua mis) ntawm ATPase H + / K +, ua cov kua roj hydrochloric acid.

Cov tshuaj muaj zog ntawm Pariet yog rabeprazole sodium, benzimidazole derivative nyob rau hauv qeb ntawm proton twj tso kua mis inhibitors. 10 lossis 20 mg ntsiav tshuaj tseem muaj: mannitol, magnesium oxide, hydroxypropylcellulose, magnesium stearate, ethylcellulose, talc, titanium dioxide, hlau oxide daj, hlau oxide liab thiab carnauba ciab.

Pariet yog tsim nyob rau hauv daim ntawv ntawm enteric-coated ntsiav tshuaj nyob rau hauv blisters ntawm 7 los yog 14 pcs .:

10 mg - liab dawb, biconvex, pleev xim, ntawm ib sab dub npav "E241",
20 mg - daj ntseg daj, biconvex, coated, nrog liab liab cim "E243".

Cov hlwv me me tau ntim rau hauv cov thawv ntawv thawv me me.

Cev xeeb tub thiab lactation

Clinically txhim khu kev qha cov ntaub ntawv ntawm kev nyab xeeb ntawm kev sau ntawv tshuaj thaum lub caij cev xeeb tub. Yog li ntawd, thaum cev xeeb tub, Pariet yog contraindicated.

Qhov cuam tshuam ntawm kev nkag mus ntawm rabeprazole sodium rau hauv cov mis ntawm tus poj niam tu neeg mob kuj tseem tsis tau kawm. Cov kws kho mob pom tias nws tsis tuaj yeem siv cov tshuaj rau kev pub niam mis.

Cov Cai Siv Tshuaj So

Tus kws kho mob daim ntawv yuav tsum tau yuav cov tshuaj no. Hauv ntau cov chaw muag tshuaj, nws tsuas yog xav tau thaum yuav Parieta hauv ib qhov tshuaj ntawm 20 mg.

Omeprazole rau pancreatitis: cov lus qhia rau kev siv
Pancreatitis Nolpase ntsiav tshuaj
Yuav noj Nexium li cas rau tus mob pancreatitis?
Mexidol rau kev mob qaij noj

Cov kws kho mob nrog exacerbation ntawm pancreatitis cwj pwm kho qhov mob ceev nrawm, enzymes thiab tshuaj pleev xim. Pariete yog thawj lub hlis dhau los, thaum kev mob tsuas yog tsim txom. Kuv tsis xav tias qhov tshuaj yuav pab tshem lawv sai. Nws tsuas yog ua txoj haujlwm sib txawv - txo cov kev zais cia thiab txo qhov txo qis ntawm txoj kev nqus ntawm pancreatic ducts. Thiab qhov nce hauv siab yog qhov ua rau kuv mob.

Nws yog ib qho nyuaj uas xav qhia rau lwm tus txog qhov koj lees paub. Omeprazole Paub Txog pab acid acid burping, kub siab thiab mob. Tab sis Pariet nyiam nrawm thiab qhov tsawg kawg ntawm kev phiv, txawm tias tus nqi siab. Kuv haus nws raws li kws kho mob sau tseg rau 2 lub lis piam txhua rau lub hlis. Kuv ntseeg hais tias kev xaiv yuav tsum tau ua nyob rau hauv kev pom zoo ntawm kev ua haujlwm, tsis pheej yig.

Tus xaib no siv Akismet los tua spam. Tshawb nrhiav seb koj cov ntaub ntawv tawm lus raug txheeb xyuas ua tiav.

Yuav siv cov pariet li cas?

Lub ntsiab tseem ceeb yog txo cov acidity ntawm lub plab, uas pab rov qab. Qhov kev ua kom loog pab kom hnov zoo nyob rau ob peb feeb.

Txawm hais tias qhov ua tau zoo ntawm cov tshuaj, tib neeg muaj ntau zaus nrhiav rau analogues, vim hais tias tus nqi ntawm cov tshuaj hauv Lavxias yog los ntawm 780 rubles.

Daim foos tso tawm - cov ntsiav tshuaj puag ncig hauv lub plhaub. Nws qhov kev tshwm sim tshwm sim nrawm dua li ntawm Omez.

Soaring yuav pab tau ntau yam los ntawm kev mob siab. Cov tshuaj yog sib txuam nrog qee cov tshuaj tua kab mob uas tau hais txog tshem tawm txoj kev mob hauv txoj hnyuv plab. Tsis tas li ntawd, qhov yuav luag tsis muaj kev mob tshwm sim ua rau nws ua tus thawj coj ntawm cov tshuaj zoo sib xws.

Cov txheej txheem tsis haum rau kev siv tuaj yeem ua raws li hauv qab no:

Kev txwv tsis pub noj cov tshuaj rau cov menyuam yaus hnub nyoog qis dua 12 xyoos.
Mob raum tsis ua rau noj tshuaj ua tsis tau.
Nws yog txwv tsis pub xaiv thiab nce qhov ntau npaum koj tus kheej.
Tsis lees txais los ntawm lub cev ntawm qee qhov sib xyaw ntawm cov tshuaj.
Cev xeeb tub thiab lactation yog lub sijhawm uas tsis tuaj yeem coj Pariet.

Qhov tsis zoo ntawm taw tes kawg tsis tau pom tseeb, tab sis nws paub tias cov tshuaj ntawm cov tshuaj yaj tau hla niam mis mus rau tus menyuam.

Lub tswv yim ntawm cov kws paub txog Pariet tsuas yog qhov zoo, vim nws tau ua pov thawj tias muaj peev xwm tshem cov khoom hauv lub cev kom ua rau cov metabolism hauv qeeb. Nyob rau hauv cov ntaub ntawv ntawm overdose, ib qho kev xav tau ceev yaug lub plab. Nws tsis muaj cov teebmeem muaj zog, yog li nws yooj yim thev los ntawm lub cev.

Nws tsis muaj kev cuam tshuam ntawm txhua lub cev. Thaum siv cov ntsiav tshuaj, lawv yuav tsum tsis txhob zom. Nws tau noj thaum sawv ntxov ua ntej noj mov.

Feem ntau, cov tshuaj tau tso cai thaum twg los tau, tab sis thaum sawv ntxov cov nyhuv yuav muaj zog dua. Txawm hais tias tus yam ntxwv zoo, nws muaj ob peb phiv. Yog tias koj nce qhov ntau npaum ntawm cov ntsiav tshuaj koj tus kheej, tom qab ntawd calcium raug tshem tawm ntawm lub cev, uas ua rau muaj kev pheej hmoo ntxiv ntawm pob txha pob txha. Yog li ntawd, kev siv tus kheej nrog lub cuab yeej no yog txwv tsis pub muaj. Cov tshuaj muaj ntau dua qhov kev tshuaj xyuas kom zoo, txawm hais tias tus nqi siab.

Thaum siv, tus neeg mob yuav ntsib kev phiv.

Cov no suav nrog:

zawv plab
cem quav
tsis muaj zog
xeev siab
qhov ncauj qhuav
daim tawv nqaij ua pob.

Pariet tsis tau noj nrog ntsiav tshuaj uas txo cov acidity ntawm lub plab.

Thawj pab rau qhov mob plab

Hauv thawj feeb ntawm cov tsos ntawm mob hauv plab, nws yog ib qho tseem ceeb kom nres qhov tsis hnov zoo. Rau qhov no, tshuaj pleev xim siv. Tsis tas li ntawd, nws yog qhov zoo dua rau kev tso cov zaub mov rau thawj zaug, es tsis txhob haus cov dej haus ntau los yog cov kua zaub uas tsis muaj roj ntau. Hauv ntau qhov xwm txheej, lwm qhov kev qhia yuav pab tau, piv txwv li:

Nrog exacerbation ntawm gastritis, cov kws kho mob pom zoo kom nyob hauv txoj hauj lwm supine ntawm sab nrog koj lub hauv caug nruj. Kev ua tau zoo dua, koj tuaj yeem tso lub txias txias rau ntawm koj lub plab lossis ua ib lub teeb taw ntawm lub plab. Thaum muaj teeb meem, nws yog ib qhov tsim nyog los haus dej thiab ua kom ntuav.
Nrog rau cov tsos mob ntawm kev lom, qhib lub pa hluav taws thiab lwm yam kev ua kom zoo yuav pab kom tshem tau qhov tsis xis nyob. Tom qab ntawd koj yuav tsum tau rov qab tsim cov dej hauv lub cev nrog cov dej haus kom ntau.

Dab tsi los haus nrog mob hauv plab yog txoj kev kho mob tuaj yeem tsuas yog txiav txim siab los ntawm kws kho mob. Nws tseem sau ntawv yuav ntau npaum li cas thiab cov chav kawm ntawm cov tshuaj. Txawm li cas los xij, muaj qee kis thaum nws tsis tuaj yeem sab laj nrog tus kws tshaj lij, tom qab ntawd koj yuav tsum xaiv cov tshuaj raws li cov tsos mob:

Nrog mob caj dab lossis mob rau sab hauv nrog muaj kua qaub ntau ntawm lub plab, kua qaub ua rau lub cev thiab kub nyhiab, cov hauv qab no yuav pab: Gastral, Anacid, De-nol, Flacarbin, Almagel.
Thaum tsis xis nyob yog los ntawm kev noj zaub mov tsis zoo, ua ntau dhau thiab lwm yam, noj: Gastromax, Mezim, Omeprazole, Cimetidine.
Nws pab txhawm rau kho mob plab: Tsis muaj-shpa, Besalol, Buscopan.
Los ntawm kem plab thiab nrog gastritis ntawm qis acidity, cov kws kho mob tau muab: Festal, Triferment, Panzinorm, Creon.

Txawm hais tias dab tsi ua rau mob plab zom mov, kev kho mob yuav tsum ua raws nraim nrog kev noj zaub mov kom zoo. Thawj thawj zaug, koj yuav tsum tsis kam tsis kam noj zaub mov, kom txog rau thaum lub zog tsis xis nyob. Tom qab ntawd cov khoom noj yuav tsum yog nyob ntawm lub rooj ntawm cov zaub mov txwv:

Nexium ntsiav tshuaj 20 mg thiab 40 mg

Nrog GERD nrog tus mob esophagitis, Nexium yuav tsum noj 40 mg ib hnub ib zaug rau 4 lub lis piam. Yog tias, tom qab ib txoj kev kho tiav, kev kho mob tsis tiav tsis tshwm sim lossis cov tsos mob ntawm tus kab mob txuas ntxiv, tom qab ntawd Nexium 40 mg yuav tsum tau noj yam tsis muaj kev so ib hnub ib zaug rau 4 asthiv.

Txog kev saib xyuas kev kho mob tom qab kho GERD nrog kev mob hlab pas kom tiv thaiv cov mob rov huam tuaj, nws yuav tsum noj Nexium 20 mg ib hnub ib zaug rau ntau lub hlis.

Nrog GERD tsis muaj es es ua pob, Nexium yuav tsum noj 20 mg ib hnub ib zaug rau 4 lub lim tiam. Yog tias tom qab kawm tiav ntawm kev kho mob cov tsos mob ntawm GERD tsis tau ploj mus, koj yuav tsum tau noj cov tshuaj ntxiv kom ntxiv rau lwm 4 lub lis piam uas tsis muaj kev cuam tshuam.

Tom qab kho GERD uas tsis muaj txoj hlab pas, Nexium tuaj yeem siv "raws li qhov xav tau", uas yog, thaum cov tsos mob mob tshwm sim, koj yuav tsum haus 1 ntsiav tshuaj ntawm 20 mg los cheem lawv. Nyob rau tib lub sijhawm, kev tswj hwm tsis tu ncua ntawm Nexium tsis yog yuav tsum tau.

Txog kev kho thiab tiv thaiv mob rov huam mob plab los yog mob rau sab hauv qhov ncauj nrog Helicobacter pylori, Nexium yuav tsum noj 20 mg ob zaug ib hnub rau ib lim tiam. Hauv kev kho mob rau peptic rwj Nexium yog siv los ntawm kev kho mob sib xyaw, thiab hauv kev siv prophylactic - hauv kev cais tawm.

Txhawm rau tiv thaiv kom rov huam mob rau cov neeg uas tau los ntshav los ntawm lub qhov txhab, Nexium rau kev siv tshuaj tiv thaiv cov kua qaub yog thawj zaug tso rau ntawm 40 mg ib hnub ib zaug rau 2 rau 3 lub lis piam, tom qab ntawd noj ntawm qhov ncauj ntawm cov ntsiav tshuaj ntawm 40 mg ib hnub ib zaug rau 4 lub lis piam.

Txog kev kho lub plab zom mov ua rau kev siv tshuaj ntev los ntawm NSAID pawg, Nexium yuav tsum noj 20 mg lossis 40 mg ib hnub ib zaug rau 4 rau 8 lub lis piam. Txog kev tiv thaiv lub plab lossis mob rwj thaum noj NSAIDs, Nexium yuav tsum noj 20 mg lossis 40 mg ib hnub ib zaug rau tag nrho lub sijhawm siv NSAIDs.

Txog kev kho mob ntawm ntau yam kab mob cuam tshuam nrog kev ua kom cov kab mob pathch ntau dhau lawm ntawm hydrochloric acid (Zollinger-Ellison syndrome, thiab lwm yam), Nexium pib noj 40 mg ob zaug ib hnub.Yog tias qhov ntau npaum li cas tsis tau coj mus rau kev tshem tawm cov tsos mob, tom qab ntawd nws yuav tsum nce ntxiv rau tus nqi ntawm tus neeg mob. Qhov siab tshaj plaws tau tso cai noj tshuaj ntawm Nexium yog 120 mg ob zaug ib hnub.

Txo qhov tshuaj ntau npaum ntawm Nexium hauv cov neeg laus thiab cov neeg txom nyem tsis tas yuav ua. Hauv kev ua rau daim siab tsis ua haujlwm, qhov ntau kawg noj tshuaj txhua hnub ntawm Nexium yog 20 mg, thiab nrog mob me thiab mob me, nws yog tib yam rau lwm tus neeg. Rau cov menyuam yaus hnub nyoog qis dua 12 xyoos, Nexium ntsiav tshuaj yog contraindicated, thiab cov hluas txij thaum 13 xyoo siv cov tshuaj hauv cov tshuaj noj rau cov neeg laus.

Qhov twg zoo dua: cov xau lossis omez?

Pariet qhov kom zoo dua yog nws cov nyhuv ntev thiab siab bioavailability. Yog li, nws tau siv nyob rau hauv qee qhov mob hnyav xws li kev rov tsim lub plab txhab hauv lub plab yav dhau los ua haujlwm rau vim li no. Nws tsis tshua muaj cov kev mob tshwm sim, zoo dua kev tiv thaiv thiab kev siv tshuaj tsis nkag rau hauv kev sib cuam tshuam yeeb tshuaj, uas yog qhov tshwj xeeb tshaj yog rau cov neeg mob uas muaj kabmob sib kis ntawm cov hlab plawv, ua pa thiab lwm lub tshuab.

Omez tsis yog siv tsis yog rau mob rau mob txhab thiab GERD, tab sis kuj tseem nyob hauv kev kho mob me: kev mob plab, cov tsos mob kem plab. Ib qhov txiaj ntsig tseem ceeb ntawm Omez yog qhov ua tau ntawm nws kev teem caij rau cov poj niam cev xeeb tub thiab menyuam yaus txij li ob xyoos (Pariet tsuas tso cai txij li 12, thiab yog contraindicated thaum cev xeeb tub).

Pariet tau tsim tshwj xeeb hauv cov ntsiav tshuaj, thiab Omez kuj tseem muaj cov ntawv rau kev tswj hwm kev cia siab, cov tshuaj sib txawv ua ke nrog domperidone, uas tsim nyog rau kev ua txhaum ntawm lub cev muaj zog ntawm lub plab zom mov. Rau cov neeg mob uas muaj teeb meem nqos ntsiav tshuaj lossis tshuaj ntsiav, muaj Omez Insta, los ntawm qhov raug tshem tawm tau npaj tau yooj yim dua rau kev nqos.

Soaring yog incomparably kim kim tshaj Omez, yog li nws yog qhov tsawg nyob rau hauv kev thov, thiab nyob rau hauv lub nroog me me nws tsis tuaj yeem pom ntawm muag.

Omez lossis Pariet - uas yog qhov zoo dua: cov lus pom ntawm kws tshaj lij

Cov kws kho mob tshwj xeeb-kws kho teeb meem feem ntau nyiam Pariet, vim tias lawv pom nws cov hauj lwm zoo dua thiab kam rau ua kom zoo dua. Qhov no tau muaj tseeb los ntawm kev tshawb fawb soj ntsuam. Cov kev tshuaj kho mob feem ntau qhia txog kev nyab xeeb ntawm Parieta hauv cov neeg laus, uas ib txwm yuam kom noj tshuaj ntau. Omez, muab nws cov tshuaj sib cuam tshuam, tsis tsim nyog hauv qhov no.

Tib qho kev khuam siab rau kev teem caij Pariet yog nws tus nqi siab: tsis yog txhua tus neeg tuaj yeem yuav nws. Yog li, nws tau pom zoo nyob rau hauv ntau qhov kev mob hnyav. Thiab rau kev kho mob ntawm kev mob plab, GERD yam uas tsis muaj kev yaig thiab rau lub hom phiaj prophylactic yog Omez.

Kev Raug Ncua (pellets lossis granules rau kev daws) Nexium - cov lus qhia rau kev siv

Pellets lossis granules yog siv los npaj qhov ncauj tawm. Txhawm rau npaj qhov kev ncua, cov ntsiab lus ntawm ib lub hnab Nexium yuav tsum tau yaj nyob rau hauv 15 ml ntawm dej tseem, sib xyaw kom zoo thiab tos 30 vib nas this kom txog thaum muaj kev cuam tshuam homogeneous. Yog tias koj yuav tsum tau noj ntau dua li ib lub hnab tshuaj, ces qhov ntim dej tau muab xam los ntawm qhov feem ntawm 15 ml ib 1 hnab. Ntawd yog, kom yaj ob lub hnab ntawm granules (pellets) Nexium yuav xav tau 30 ml dej, thiab lwm yam. Qhov kev ncua ntawv tiav yuav tsum quag cawv tam sim lossis rau ntau ntawm ib nrab ib teev. Tom qab haus cov kev ncua, ntxiv lwm 15 ml dej rau hauv tib lub khob, nplawm cov khoom uas seem thiab haus cov tshuaj tov dua. Rau kev npaj nrawm ntawm Nexium daws, granules yuav tsum tsis txhob zuaj lossis av.

Tsuas noj thiab sijhawm ntawm kev kho mob yog txiav txim siab raws lub hnub nyoog ntawm tus neeg thiab hom kab mob.

Rau cov menyuam yaus hnub nyoog 1 txog 11 xyoos nrog lub cev nyhav dua li 10 kg, Nexium pellets yuav tsum muab rau kev kho mob GERD nkaus xwb. Kev kho mob ntawm GERD nrog esophagitis hauv cov menyuam yaus uas muaj lub cev nyhav txog 10 - 20 kg yog nqa nrog Nexium 10 mg (1 sachet) 1 zaug hauv ib hnub rau 8 lub lis piam. Yog tias tus me nyuam lub cev qhov hnyav dua 20 kg, tom qab ntawd rau kev kho mob GERD nrog txoj hlab pas, nws tuaj yeem noj Nexium 20 mg (2 lub hnab) ib hnub ib zaug kuj siv tau 8 lub lis piam. Txhawm rau kho GERD yam uas tsis muaj txoj hlab pas, cov menyuam yuav tsum noj Nexium 10 mg (1 sachet) 1 zaug nyob rau ib hnub rau 8 lub lis piam.

Cov neeg laus thiab cov menyuam yaus hnub nyoog 12 xyoos siv Nexium pellets (granules) hauv tib lub tshuaj thiab raws li cov qauv thiab cov cai uas ua cov ntsiav tshuaj (saib ntu "Nexium 20 mg thiab 40 mg ntsiav tshuaj - cov lus qhia rau kev siv").

Txo qhov txo qis tsis tas yuav tsum muaj rau cov neeg laus, nyob rau hauv cov kev txom nyem los ntawm lub raum tsis ua haujlwm thiab mob me lossis mob hnyav daim siab ua haujlwm. Hauv kev ua rau daim siab ua haujlwm ntau, kev noj tshuaj ntawm Nexium tsuas pub txog 20 mg (2 sachets) ib hnub.

Lyophilisate Nexium - cov lus qhia rau kev siv

Kev siv tshuaj tiv thaiv kom zoo yog siv los hloov lwm cov ntsiav tshuaj lossis pellets yog tias ib tug neeg tsis tuaj yeem nqos cov tshuaj rau ib qho laj thawj twg. Sai li qhov peev xwm nqos tau cov tshuaj tau zoo, tus neeg tau pauv mus rau kev txais tos ntawm Nexium nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj lossis pellets. Qhov ntau npaum li cas ntawm kev tso dej khov ntawm Nexium yog txiav txim siab los ntawm hom kab mob.

Txog kev kho mob GERD nrog mob esophagitis, Nexium yog muab ntawm 40 mg (1 lub raj mis) ib hnub ib zaug. Txhawm rau tshem tawm cov tsos mob ntawm GERD, kev ua mus ntxiv tsis muaj txoj hlab pas, 20 mg (ib nrab lub raj mis) ntawm lyophilisate yog tswj hwm.

Txog kev kho thiab tiv thaiv ntawm qhov mob ua kom tsis haum nrog kev siv cov NSAIDs, Nexium tseem siv 20 mg (ib nrab lub raj mis) ib hnub ib zaug.

Txhawm rau tiv thaiv los ntshav los ntawm mob peptic tom qab kev mob qog nqaij, 80 mg (2 lub raj mis) ntawm Nexium yuav tsum tau muab rau noj ua ib qho kev lis ntshav nyob ntev ib nrab teev. Tom qab ntawd, Nexium raug tswj hwm nyob rau hauv daim ntawv ntawm cov kua roj (nqus ntshav) ntawm tus nqi ntawm 8 mg rau ib teev rau 3 hnub. Tom qab ua tiav ntawm kev tso ntshav tawm ntawm Nexium, koj yuav tsum hloov mus rau kev noj tshuaj nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj lossis pellets ntawm 40 mg ib zaug ib hnub rau 4 lub lis piam.

Cov kev cai npaj rau kev npaj cov kev daws rau kev txhaj tshuaj thiab qe ntshav (cov neeg mob):

Lyophilisate yuav tsum tau yaj tsuas yog muaj cov ntsev ua kom tsis haum,
Cov tshuaj Nexium npaj txhij tsis tuaj yeem tov nrog lwm cov tshuaj,
Txoj kev daws teeb meem yuav tsum ua kom pom tseeb yam tsis muaj impurities lossis plaub ya ri,
Txoj kev daws teeb meem yuav tsum tau muab cov tshuaj tam sim tom qab npaj lossis rau qhov siab tshaj plaws ntawm 12 teev,
Koj tuaj yeem khaws cov tshuaj ntawm qhov kub uas tsis tshaj 30 o C,
Rau kev txhaj tshuaj, cov lyophilisate los ntawm ib lub raj mis yuav tsum tau yaj los ntawm kev ntxiv 5 ml ntawm physiological saline,
Rau ib qho dej ntws (nqus ntshav), lyophilisate los ntawm ib lub raj mis yuav tsum tau yaj hauv 100 saline.

Cov kev cai rau kev tswj kav dej ntawm cov tshuaj lyophilisate:

40 mg lossis 20 mg ntawm Nexium (1 lossis 0.5 lub raj ntawm cov dej haus lyophilisate) yog muab rau tsawg kawg 3 feeb,
40 mg lossis 20 mg ntawm Nexium (1 lossis 0.5 vial ntawm cov lyophilisate yaj) yog muab ua kev lis ntshav dhau 10 mus rau 30 feeb,
80 mg ntawm Nexium (2 vials) tau muab rau ua qhov kev lis ntshav rau tsawg kawg 30 feeb,
Txhua qhov tsis siv ntawm cov tshuaj lyophilisate yuav tsum tau muab pov tseg, tsis khaws cia.

Yog tias koj muaj kev ntuav, ua teeb meem nqos, lossis ua rau lub cev poob thaum noj Nexium, koj yuav tsum sab laj nrog kws kho mob thiab soj ntsuam lwm yam kab mob. Thaum noj Nexium rau ntau tshaj ib xyoos, nws yuav tsum pom los ntawm kws kho mob. Yog tias thaum lub sijhawm siv Nexium "ntawm kev thov" muaj qhov txawv txav ntawm cov tsos mob, ces koj yuav tsum sab laj tus kws kho mob sai li sai tau.

Kev cuam tshuam nrog lwm yam tshuaj

Nexium cuam tshuam nrog cov tshuaj tiv thaiv kab mob HIV / AIDS (atazanavir, ritonavir, nelfinavir, saquinavir), ua rau muaj kev hloov pauv hauv lawv txoj kev nqus thiab kev nqus hauv cov ntshav. Ntxiv mus, kev nce ntxiv hauv cov tshuaj ntau dua ntawm cov tshuaj tiv thaiv kab mob tsis ua kom tsis muaj txiaj ntsig ntawm Nexium, yog li, cov tshuaj no tsis tuaj yeem siv ua ke.

Nexium ua rau kev nce hauv kev tso siab hauv cov ntshav ntawm cov tshuaj hauv qab no:

Diazepam
Citalopram,
Imipramine
Clomipramine,
Phenytoin
Cilostazol

Nrog tib lub sij hawm siv Nexium nrog cov tshuaj saum toj no, qhov ntau npaum ntawm qhov kawg yuav tsum raug txo los ntawm 30 - 40%.

Rifampicin thiab kev npaj ua tiav nrog St. John lub wort Cheebtsam ua rau txo qis ntawm cov tshuaj Nexium hauv cov ntshav ntshav.

Nexium rau menyuam yaus - yuav ua li cas noj

Cov menyuam yaus uas lub cev hnyav dua li 10 kg thiab qis dua 1 xyoos yuav tsum tsis txhob noj Nexium. Cov menyuam yaus hnub nyoog 1 txog 11 xyoos nrog lub cev hnyav ntawm 10 txog 20 kg tuaj yeem noj 10 mg xwb (1 sachet) ntawm Nexium ib hnub ib zaug. Cov menyuam yaus lub cev hnyav dua 20 kg tuaj yeem noj 20 mg (2 sachets) ntawm Nexium hauv ib hnub.

Nexium nyob rau hauv cov menyuam yaus tsuas yog siv rau kev kho mob GERD, uas muaj nyob hauv kev noj txhua hnub ntawm 10 mg lossis 20 mg ntawm pellets rau 8 lub lis piam.

Nexium - analogues

Txhais ntawm Nexium yog cov tshuaj hauv qab no:

Neo-Sext
Cov tshuaj Esomeprazole
Emanera tsiav tshuaj.

Cov tshuaj Nexium yog cov tshuaj hauv qab no:
1. Beret tshuaj,
2. Lub plab zom mov tsiav tshuaj,
3. Tshuaj Helikon,
4. Dexylant tsiav tshuaj,
5. Zhelkizol lyophilisate,
6. Zerocide tsiav tshuaj,
7. Cov ntsiav tshuaj Zipantola
8. Zolispan ntsiav tshuaj
9. Zulbeks ntsiav tshuaj
10. Tswj cov ntsiav tshuaj thiab hmoov rau qhov kev npaj daws teeb meem rau kev tswj kav dej,
11. Krosacid ntsiav tshuaj
12. Lanzabel tsiav tshuaj,
13. Lanzap tsiav tshuaj,
14. Lansoptol tsiav tshuaj,
15. Lansoprazole Stada Capsules,
16. Lansofed tsiav tshuaj,
17. Lantsid tsiav tshuaj,
18. Losek ntsiav tshuaj thiab lyophilisate,
19. Lozenzar-Sanovel Capsules,
20. Nolpase ntsiav tshuaj,
21. Noflux ntsiav tshuaj
22. Omez tsiav tshuaj thiab lyophilisate,
23. Omez Insta hmoov rau kev tshem tawm qhov ncauj,
24. Omecaps tsiav tshuaj,
25. Omeprazole tsiav tshuaj,
26. Omeprus tsiav tshuaj,
27. Omefes tsiav tshuaj,
28. Omizak tsiav tshuaj,
29. Omipix tsiav tshuaj,
30. Omitox tsiav tshuaj,
31. Ontime ntsiav tshuaj
32. Cov tshuaj ntsiav Orthanol,
33. Ocid tshuaj ntsiav,
34. Pantaz ntsiav tshuaj
35. Cov tshuaj Panum,
36. Soaring tshuaj ntsuab
37. Tsiav tshuaj Parkour,
38. Peptazole ntsiav tshuaj
39. Pizhenum - Sanovel ntsiav tshuaj,
40. Pleoma-20 tsiav tshuaj,
41. Prosthesis tsiav tshuaj
42. Cov ntsiav tshuaj Puloref,
43. Rabeprazole-OBL Capsules
44. Rabelok lyophilisate,
45. Romesek tsiav tshuaj,
46. Sanpraz ntsiav tshuaj thiab lyophilisate,
47. Txoj kev daws teeb meem
48. Ulcosol tsiav tshuaj thiab lyophilisate,
49. Ultra ntsiav tshuaj,
50. Cov tshuaj ntsiav Ultop thiab lyophilisate,
51. Ntsiav tshuaj Hayrabesol,
52. Helicide tsiav tshuaj thiab lyophilisate,
53. Cisagast tsiav tshuaj,
54. Epicurus tsiav tshuaj.

Nexium Xyuas

Tsawg tsawg ntawm kev tshuaj xyuas tsis zoo txog cov tshuaj Nexium tsis tshua muaj vim nws tsis muaj txiaj ntsig. Feem ntau, cov laj thawj rau kev tshuaj xyuas tsis zoo yog qhov kev cia siab ntau txog cov tshuaj, thaum tib neeg xav tias "cov ntsiav tshuaj khawv koob" yuav tsis tsuas yog tshem tawm cov tsos mob lossis kho tus kab mob, tab sis yuav ua rau lawv muaj kev noj qab haus huv.

Omez lossis Nexium?

Lub hauv paus ntawm qhov ua tau zoo ntawm Nexium yog nws qhov siab bioavailability, uas yog qhov muaj txiaj ntsig zoo dua li qhov ntawm txhua cov tshuaj los ntawm cov pab pawg ntawm proton twj tso kua mis inhibitors ntawm thawj tiam, uas suav nrog Omez. Lub bioavailability ntawm Nexium yog xyuas los ntawm nws cov qauv tshuaj tshwj xeeb, vim tias nws nce mus txog lub plab lub plab hauv qhov ntau ntau dua piv rau Omez. Tsis tas li ntawd, Nexium muaj lub peev xwm los tswj kom ruaj khov thiab tsis tu ncua nyob rau hauv cov ntshav tom qab noj, thaum Omez tsis. Thaum noj Omez, qhov kev txiav txim siab ntawm cov tshuaj yeeb dej caw hauv cov ntshav nws txawv heev, uas ua rau muaj qhov mob tshwm sim ntxiv rau lub sijhawm.

Hais txog kev kho mob kom zoo, cov txiaj ntsig ntawm Nexium hla Omez yog raws li hauv qab no:
1. Zoo dua thiab meej dua ua ntej kwv yees hloov pauv hauv pais plab acidity.
2. Feem pua siab kho thaum lub sij hawm luv luv ntawm kev kho.
3. Kev tshem tawm ntawm cov tsos mob mob thiab kho kom zoo ntawm qhov tsis xws luag ntawm lub plab zom mov ntawm lub plab, duodenum thiab esophagus.
4. Tiv thaiv kev mob siab thiab lwm cov tsos mob ntawm GERD nyob rau ntau tus neeg mob.

Hauv nws txoj kev kuaj mob, Nexium yog zoo dua rau tag nrho lwm cov tshuaj ntawm proton twj tso kua mis inhibitor pawg. Yog li, thaum lub sijhawm sim tshuaj kho mob tau pom tias Nexium ua tiav kev kho mob GERD hauv ib hlis, thiab Omezu yuav xav tau li ob lub hlis kom ua tiav cov txiaj ntsig ib yam.

Thaum kho lub plab lossis lub plab duodenal cuam tshuam nrog Helicobacter pylori, kev siv ntawm Nexium ua ke nrog cov tshuaj tua kab mob los tua cov microbe tshwm sim ua kom tiav kev kho mob thiab ua kom mob ntawm lub rwj nyob rau hauv tsuas yog xya hnub. Rau kev sib piv, koj yuav tsum paub tias kev kho mob qauv nrog omez lossis lwm qhov kev tso kua mis proton ua kom tiav tsis pub dhau peb lub lis piam. Ntawd yog, kev siv Nexium hauv kev sib xyaw ua ke kho peptic rwj txo lub sijhawm kho los ntawm peb zaug.

Yog li, nws tuaj yeem hais tau kiag li tsis tau hais tias Nexium muaj cov khoom zoo dua thiab muaj kev sib zog ntau dua los ntawm kev sib piv piv rau Omez.

Nexium lossis Emanera?

Nyob rau hauv tus txheej txheem ntawm kev tsim cov tshuaj qub, kev sib txuas ua ke thiab rho tawm ntawm cov tshuaj nquag, nws cov tshuaj ntxuav tawm huv thiab ua tib zoo kawm txog cov khoom tau nqa tawm. Tsuas yog tom qab kev txhim kho ntawm lub thev naus laus zis rau kev npaj thiab ua kom huv ntawm ib yam khoom los ntawm kev ua kom tsis huv yog nws muaj nyob rau hauv qhov muaj pes tsawg leeg tshuaj thiab tiv thaiv los ntawm daim ntawv tso cai. Lawm, tag nrho cov nuances ntawm thev naus laus zis rau kev tsim cov khoom nquag yog kev lag luam thiab kev lag luam zais cia. Tab sis lwm lub tuam txhab kuj tseem tuaj yeem ua ke cov tshuaj no thiab tso cov tshuaj nyob rau hauv lub npe sib txawv, uas yuav raug suav tias yog tsis muaj lub zog, vim tias kev zoo siab hauv kev tshawb pom ntawm cov tshuaj sib txuas nrog rau lwm qhov kev txhawj xeeb.

Cov tuam txhab lag luam feem ntau tsis ntxuav cov tshuaj nquag ua kom huv si, siv lwm cov tshuaj tiv thaiv, vim tias cov tshuaj muaj peev xwm muaj ntau zaus ntau dua thiab qhov mob ntawm cov kev mob tshwm sim, thiab cov chaw kho mob muaj txiaj ntsig tsawg dua li qhov qub. Yog li ntawd, qhov sib txawv ntawm daim tseem thiab qhov ntau yog pom tseeb.

Txawm li cas los xij, Emanera tsis yog qhov dog dig tsis tu ncua ua los ntawm cov tuam txhab suav Indian suav tshuaj. Qhov tseeb yog tias Emanera yog ua los ntawm cov kws paub zoo txog kev txhawj xeeb txog tshuaj Krka, uas tau muab cov ntaub ntawv tsim nyog los tsim cov tshuaj feem ntau tshwj xeeb kom tau txais cov tshuaj pheej yig dua. Yog li ntawd, qhov sib txawv ntawm Emanera thiab Nexium yog qhov tsis muaj txiaj ntsig, thiab koj tuaj yeem xaiv cov tshuaj twg. Yog tias nws yog qhov yuav tsum tau ua kom txo qis tus nqi ntawm kev kho mob, ces pheej yig dua Emanera yuav tsum tau nyiam. Thiab thaum tsis muaj ib qho kev txwv, koj tuaj yeem xaiv Nexium. Yog tias tsis muaj cov ntaub ntawv tseem ceeb yuam kom peb xaiv Nexium lossis Emanera, tom qab ntawd koj tuaj yeem yuav cov tshuaj uas koj nyiam rau qee qhov laj thawj, piv txwv li, lub ntim khoom zoo nkauj dua, thiab lwm yam.

Nexium - yuav ua li cas yuav?

Cov ntaub ntawv tsis raug qee lub sijhawm hauv Is Taws Nem ntawm qhov teeb meem no, yog li peb yuav nkag siab ntau yam ntxiv.

Omeprazole thiab rabeprazole txheeb rau proton twj tso kua mis inhibitors (IPP). Sib Tham - proton twj tso kua mis blockers Cov. Cov no yog cov tshuaj uas inhibit qhov zais cia ntawm hydrochloric acid (HCl) hauv plab, yog li lawv muaj feem cuam tshuam nrog antisecretory tshuaj thiab yog siv los kho ntau acidity ntawm lub plab. Proton twj tso kua mis inhibitors (proton twj tso kua mis blockers) txo kev zais cia hydrogen ions (H +, lossis proton) sab hauv (parietal) cov kab mob ntawm lub plab. Cov kev qhia tawm zais cia muaj nyob rau hauv cov pa roj carbon ntau ntawm cov pa roj carbon monoxide ion (K +) nkag mus hauv lub cell hauv kev sib pauv rau kev tshem tawm ntawm hydrogen ion (H +).

Kev faib tawm thiab Cov Cwj Pwm

Tam sim no thov 3 pawg tshuaj uas txo cov acidity hauv plab:

proton twj tso kua mis inhibitors - yog cov tshuaj tua kab mob uas muaj zog tshaj plaws uas txwv kev tsim ntawm hydrochloric acid hauv plab. Txais 1-2 zaug nyob rau ib hnub,
H 2 blockers (nyeem al-ob) - lawv muaj kev siv tshuaj antisecretory tsawg thiab yog li tsuas yog tuaj yeem ua rau mob hnyav. Lawv raug noj 2 zaug hauv ib hnub. Cov tshuaj tiv thaiv histamine (H 2 -) cov neeg tau txais lub parietal hlwb ntawm lub plab hnyuv txhaws. H 2 blockers muaj xws li ranitidine thiab kev tshaib plab .

Rau kev siv: H 1 -blockers tau siv tiv thaiv kev ua xua (loratadine, diphenhydramine, cetirizine thiab lwm tus).

tshuaj tiv thaiv kab mob (txhais lus "tawm tsam cov kua qaub ") - txhais tau tias yog raws li cov khoom sib xyaw ntawm cov magnesium lossis aluminium, uas sai sai nruab nrab (khi) hydrochloric acid hauv plab. Cov no suav nrog almagel, phosphalugel, maalox thiab lwm tus. Lawv tau ua sai sai, tab sis ntev mus (hauv 1 teev), yog li lawv yuav tsum tau noj ntau zaus - 1.5-2 teev tom qab noj mov thiab ua ntej yuav mus pw. Txawm hais tias antacids txo acidity hauv plab, lawv ib txhij nce lub zais ntawm hydrochloric acid los ntawm lub tshuab cov tswv yim tsis zoo vim lub cev sim rov qab pH (acidity, nws yog los ntawm 0 txog 14, qis dua 7 - acidic ib puag ncig, siab dua 7 - alkaline, raws nraim 7 - nruab nrab) rau yav dhau los cov nuj nqis (pH ib txwm hauv lub plab yog 1.5-2).

Rau proton twj tso kua mis inhibitors suav nrog:

(pauv cov npe - omez, ploj, ultop ),
(pauv cov npe - Nexium, Emanera ),
lansoprazole (pauv cov npe - lantsid, lansoptol ),
pantoprazole (pauv cov npe - nolpaza, tswj hwm, kev tiv thaiv kev nyiam huv ),
rabeprazole (pauv cov npe - xau, noflux, ontay, zulbeks, hairabesol ).

Nqe Sib Piv

Omeprazole nqi ob peb zaug pheej yig dua rabeprazole .

Tus nqi ntawm cov generics (analogues) rau 20 mg ntawm 30 tsiav tshuaj hauv Moscow rau Lub Ob Hlis 14, 2015 yog los ntawm 30 txog 200 rubles. Rau lub hli kho, 2 pob yog xav tau.

Tus nqi ntawm cov tshuaj qub Xau (rabeprazole ) 20 mg 28 tab. - 3600 RUB. Rau lub hli ntawm kev kho mob, 1 pob yog xav tau.
(analogues) rabeprazole yog qhov pheej yig dua:

Ontime 20 mg 20 tab. - 1100 RUB.
Zauv Paj 20 mg 28 tab. - 1200 rub.
Hairabesol 20 mg 15 tab. - 550 rub.

Ua li no nqi kho mobhauv ib hlis yog kwv yees li 200 rubles (40 mg / hnub), rabeprazole thaum siv hairabesola - txog 1150 rubles. (20 mg / hnub).

Qhov sib txawv ntawm omeprazole thiab esomeprazole

Nws yog S-stereoisomer (sab laug kho qhov muag isomer), uas sib txawv ntawm txoj cai sab xis isomer tib txoj hauv kev sab laug thiab sab tes lossis sab laug thiab sab laug khau raj. Nws muab tawm tias R-daim ntawv muaj zog ntau dua (tshaj li S-daim ntawv) raug rhuav tshem thaum dhau los ntawm daim siab thiab yog li ntawd tsis ncav cuag lub lining hlwb ntawm lub plab. Omeprazole yog sib xyaw ntawm ob tus stereoisomers no.

Raws li cov ntaub ntawv, nws muaj qhov tsis zoo zoo piv rau, tab sis tus nqi ntau dua. noj nyob rau hauv tib cov tshuaj li.

Nqi cov npe lag luam yog:

Nexium 40 mg 28 tab. - 3000 mos.
Emanera 20 mg 28 tab. - 500 pluaj. (2 ntim ib hlis twg).

Cov txiaj ntsig zoo ntawm rabeprazole dhau ntawm lwm cov PPI

Nyhuvrabeprazole pib hauv 1 teev tom qab kev tswj hwm thiab kav ntev li 24 teev. Cov tshuaj ua rau qhov dav dua pH (0.8-4.9).
Tsuas tshuaj rabeprazole yog 2 zaug qis dua piv nrog omeprazole, uas ua kom zoo dua siab dua rau cov tshuaj thiab cov kev mob tshwm sim tsawg dua. Piv txwv, hauv ib qhov kev tshawb nrhiav, phiv (mob taub hau, kiv taub hau, raws plab, xeev siab, tawv nqaij ua pob ) tau sau tseg rau ntawm 2% hauv kev kho mob rabeprazole thiab u 15% thaum kho.
Nkag rabeprazole mus rau hauv cov ntshav los ntawm cov hnyuv (bioavailability) tsis nyob ntawm lub sijhawm noj mov.
Rabeprazole ntau txhim khu kev qha inhibits qhov zais cia ntawm hydrochloric acid, vim tias nws txoj kev rhuav tshem hauv daim siab tsis yog nyob ntawm kev sib txawv caj ces ntawm cytochrome P450 enzyme ntau. Yog li, nws yog qhov ua tau kom tau zoo dua los twv seb qhov tshwm sim ntawm cov tshuaj hauv cov neeg mob sib txawv. Rabeprazole tsawg dua li lwm yam tshuaj cuam tshuam rau cov metabolism (rhuav tshem) ntawm lwm yam tshuaj.
Tomqab tsis ua haujlwm rabeprazoletsis muaj "kev rov ua mob" (tshem tawm), i.e. tsis muaj qhov nyiaj them rov qab ntxiv ntawm qib uas muaj acidity hauv lub plab. Hydrochloric acid secretion tau rov qab maj mam (hauv 5-7 hnub).

Kev qhia rau noj proton twj tso kua mis inhibitors

gastroesophageal reflux disease (reflux ntawm cov kab mob acidic ntawm lub plab mus rau txoj hlab nqos mov),
pathological hypersecretion ntawm hydrochloric acid (suav nrog Zollinger-Ellison syndrome),
hauv kev kho nyuaj nws yog siv los tshem tawm (tshem tawm) Helicobacter pylori mob (Helicobacter pylori), uas ua rau mob ncauj plab thiab mob plab hnyuv ntev.

Lus khaws xav Txhua yam proton twj tso kua mis inhibitors puas lawm hauv ib puag ncig acidic , yog li ntawd, muaj nyob rau hauv daim ntawv ntawm tshuaj ntsiav lossis enteric ntsiav tshuaj, uas nqos tau tag nrho (koj tsis tuaj yeem zom).

Luv luv: rabeprazole ≅ esomeprazole> omeprazole, lansoprazole, pantoprazole .

Nyob hauv kev nthuav dav: rabeprazole muaj ntau yam zoo ua ntej lwm cov tshuaj tiv thaiv proton twj tso kua mis thiab hais txog cov hauj lwm zoo piv rau, txawm li cas los xij, kev kho mob rabeprazole raug nqi 5 zaug kim dua piv thiab me ntsis kim piv piv.

Raws li cov ntaub ntawv, kev ua haujlwm ntawm Helicobacter pylori kev tshem tawm tsis yog nyob ntawm kev xaiv ntawm cov kev tiv thaiv tshwj xeeb cov tshuaj tiv thaiv proton twj tso kua mis (muaj ib qho ua tau), thaum nyob hauv kev kho mob gastroesophageal reflux tus kab mob feem ntau cov kws sau ntawv pom zoo nws rabeprazole .

Cov tshuaj tiv thaiv antihypertensive piv txwv

Ntawm proton twj tso kua mis inhibitors 3 cov tshuaj tau muab faib:

(tshuaj hauv paus nrog phiv)
(kev ua zoo dua los ntawm S-stereoisomer ntawm omeprazole),
rabeprazole (nyab xeeb).

Qhov ntsuas zoo sib xws yog muaj ntawm cov neeg siv los kho ntshav tawm:

amlodipine (nrog kev phiv)
levamlodipine (qhov kev ua tau zoo dua los ntawm S-stereoisomer nrog qhov kev mob tshwm sim tsawg kawg),
lercanidipine (feem ntau ruaj ntseg).

Cov lus qhia 7 rau qhov sau cia “Qhov twg zoo dua - omeprazole lossis rabeprazole? Cov txiaj ntsig ntawm rabeprazole "

Cov txiaj ntsig ntawm Hyrabesol:
Hyrabezol raug pom zoo rau menyuam yaus txij li 12 xyoo.
Txee lub neej ntawm Hairabesol yog 3 xyoos.
Kev ntaus cim tshwj xeeb rau cov cim xeeb rau ob lub cev.
Hyrabezol ywj siab hais txog kev tau zaub mov noj

Kuv zaj dab neeg yog qhov no: tus kws kho mob tau sau Ultop rau kuv. Tom qab siv ib zaug, muaj kev mob tshwm sim loj heev: mob taub hau ntse, khaus thiab pib pom qhov muag ib qho tsis zoo, palpitations thiab kub taub hau. Dokhtura tau hais txog qhov no, tab sis nws tsis ntseeg kuv - nws hais tias tsis tuaj yeem muaj qhov tshwm sim zoo li no los ntawm ultop thiab tsa Omez-insta. Kuv los tsev, Kuv txiav txim siab los nyeem, tab sis nws hloov tawm mus ua tib qho khoom plig, tsuas yog nyob hauv lwm lub npe txawv!

Nyob rau hauv dav dav, ua tsaug rau koj, Kuv tau enlightened thiab kuv yuav saib rau kuv tus kheej ib txwm hloov tsis muaj ib tug txaus ntshai phiv. Kuv vam tias kuv yuav nrhiav tau tus kws kho mob nkeeg zoo tam sim no ... ((((

4 xyoos dhau los, nws tau kho tus mob gastritis nrog tus mob ultrasound, zoo li tsis pab, vim tias kev yaig ntawm lub plab tau tshawb pom xyoo no. xa zulbeks. Kuv tsis mus rau hauv lub ntiaj teb tom ntej nrog 2 ntsiav tshuaj: ib teev tom qab noj tshuaj, kuv lub caj pas tau mob rau thawj hnub thiab hnoos pib, kuv lub qab los ploj, thiab thaum sawv ntxov nyob rau hnub thib ob muaj mob hauv qab plab ib yam li mob cystitis. txawm li cas los txiav txim siab haus lwm ntsiav tshuaj. ib zaug ntxiv, ib teev tom qab kev noj, qhov kub tau nce 38.5, qis rov qab tau mob, lub taub hau tsis xav li cas, mob ib ce hauv tag nrho lub cev, txhua yam rumbled sab hauv. Kuv nyeem hauv cov kev mob tshwm sim tsuas yog tom qab ntawd zulbeks feem ntau ua rau cov kab mob zoo li ua npaws thiab kis kab mob ntawm cov genitourinary system. thiab nov yog yam tshuaj muaj kev nyab xeeb tshaj plaws uas koj xav hais. nrog ultrasope no tsis yog, qhov ncauj ntau tshaj plaws thiab tsis qab los noj mov. los ntawm txoj kev, kab tias ntau txoj kev noj tshuaj 20 mg yog qhov loj heev rau kuv, vim Kuv tus luj yog 39 kg

Hmoov tsis zoo, Zulbeks (rabeprazole), txawm hais tias nws zoo, nws tsis muaj kev nyab xeeb zoo li nws zoo li nyuam qhuav pib. Ntawm qhov tod tes, Ultop (omeprazole) kuj tseem muaj peev xwm ua rau cov nkees nkees dav dav, dav dav tsis muaj zog, ua kom yuag, thiab kub cev. Cov teebmeem no tau piav qhia nyob rau hauv cov lus qhia rau tshuaj. Raws li rau qhov ntau npaum, 10 lossis 20 mg ntawm rabeprazole ib hnub (tsis ntau tshaj 20 mg) feem ntau siv. Yog li, rabeprazole tsis haum koj, koj yuav tsum rov qab mus rau omeprazole lossis sim esomeprazole.

Tsaug rau saib. Kuv nyeem, tab sis ib tus kws kho mob tau sau ntawv rau kuv, thiab tau hais tias cov tshuaj tau zoo tiv thaiv thiab nws pab zoo heev. Tab sis tsis qhia kuv tias ntev npaum li cas nws tau tas los ntawm lub cev? Niaj hnub no kuv tsis tau noj ib qho tshuaj ntxiv, tab sis kuv qhov kub tseem nyob ib puag ncig 37.3, mob lub nraub qaum tau dhau mus, mob caj pas tau mob tsawg dua, kuv qhov kev qaug zog ploj mus, kuv lub siab rov qab los. lub sijhawm kawg kuv coj cov tshuaj ib hnub dhau los. txog ultop Kuv tau nco qab tias ntawm nws kuv cov plaub hau pib poob qis heev (qhov no kuj tau hais tseg hauv cov lus qhia).

Rabeprazole nws tus kheej tau raug tshem tawm ntawm lub cev sai heev, tsuas yog cov kab ntsab tom qab ib hnub, txawm li cas los xij, cov nyhuv ntawm cov tshuaj nyob ntev txog ib hnub. Feem ntau yuav yog, hauv 4-5 hnub, cov kev mob tshwm sim yuav ploj mus. Raws li hloov chaw, koj tuaj yeem sim esomeprazole, lossis hloov mus rau H 2 blockers, tab sis lawv thaiv lub zais ntawm hydrochloric acid yog qhov ntau tsis muaj zog.

Nyob zoo Kuv tau nyeem Jeanne qhov kev tshuaj xyuas thiab tau zoo siab me ntsis :) lub caij nplooj ntoo hlav muaj kab mob voos, nws tau raug sau rau parry - muaj lub zog tsis muaj zog ntawm nws, hloov nrog nullase - nws tau mob heev hauv thaj chaw ntawm lub hnub ci thiab qhov muag plooj. Hloov nrog nexium dropper. Thaum xub thawj muaj lub siab txias thiab xav tsis thoob, tom qab ntawd qhov kev xav zoo li xuab zeb tau los ntawm ob lub raum, nyob rau hnub thib 2 kuv lub qa thiab qhov kub tau 37, tom qab ntawd ob peb hnub tom qab ntawd nws tseem sawv, ua paug ntawm kuv lub caj pas. Kuv pom qhov no hauv kuv cov ntawv - lawv nug kuv kom nqa cov ntawv teev menyuam li no.

Maj mam, cov kev mob tshwm sim ploj, cov tshuaj tau raug muab tso tseg, tab sis kev noj haus tau pom tag nrho lub caij ntuj sov, vim tias ib qho kev ua yuam kev me me ua rau muaj qhov khaus khaus ntawm thaj av ntawm sab laug lub xub pwg hniav. Ib lub lim tiam dhau los, nws tau pib hlawv ntxiv ntau zaus hauv cov scapula, tawm tsam keeb kwm ntawm 1 hmo ntuj casting (pom qhov kev sib tw kis las ntawm lub plab khoob). Tom qab ntawd sab xis tau pib mob heev thiab tsis muaj zog pib. Kuv tau sim pab Seth nrog Iberogast, Suav cov tshuaj yej, tab sis kuv yuav tsum tau mus noj tshuaj. Kuv pib haus Nexium nag hmo - thaum yav tsaus ntuj, mob ib ce thiab tsis muaj zog. Niaj hnub no tsis muaj zog txhua hnub, txaus ntshai ua tsis muaj zog, Kuv tuaj yeem nyuaj taug kev. Ntxiv caj pas mob siab thiab kub tau nce 37-37.5. Thaum xub thawj kuv xav tias kuv mob, tab sis tsis muaj lwm yam cim ntawm tus kab mob thiab yaug tsis pab. Hauv lub caij nplooj ntoo hlav nws zoo rau kuv tias tsis muaj kev phiv ntau, tsawg kawg yog tsis muaj qhov tsis muaj zog. Yam tshuaj twg thiaj tuaj yeem hloov? Koj tuaj yeem hais dab tsi txog famotidine? Txog nws cov kev mob tshwm sim?

Pariet (rabeprazole), nolpase (pantoprazole), nexium (esomeprazole) zwm rau cov pab pawg ntawm cov twj tso kua mis blockon thiab tuaj yeem ua rau muaj kev phiv zoo sib xws: ua npaws thiab zoo li mob khaub thuas. H2-blockers (famotidine, ranitidine, roxatidine, nizatidine) ua rau kub taub hau me ntsis, yog li koj yuav tsum tau sim lawv. Lawv muaj lwm cov kev mob tshwm sim, tab sis muaj txoj hmoo tias koj yuav tsis muaj lawv los yog tsuas muaj tsawg. Pom cov kev mob tshwm sim ntawm cov tshuaj ntawm lub xaib. rlsnet.ru Sim ua ntej cov H2 blockers uas haum rau koj rau tus nqi. Feem ntau, H2 blockers tsis muaj zog dua li cov twj blockon. Tsuas yog tsis txhob siv cov cimetidine, nws yog ib qho tshuaj yeeb uas tsis muaj qhov coob uas muaj kev phiv tshuaj.

Cov tshuaj tiv thaiv zoo tshaj plaws ntawm rabeprozole (soars, noflux, sijhawm, zulbeks, hairabesol) yog dab tsi?

Hauv kev tshawb xav, tag nrho cov analogues yuav tsum muaj sib npaug. Cov tshuaj muaj npe kev lag luam (npe, thawj qhov nkag rau hauv khw) yog Pariet. Nws feem ntau ntseeg tias cov tshuaj zoo tshaj plaws yog cov tuam txhab tsim khoom lag luam European, Asmeskas thiab Israeli. Tab sis nco ntsoov tias fakes yog qee zaum muag hauv Lavxias. Yog li, koj tuaj yeem siv ib qho analogue (qhov tsis tseem ceeb) yog tias nws pab koj thiab tsis ua rau muaj kev phiv tshuaj.

Kuv tau muaj mob txij xyoo 1994. Kuv muaj qhov kho mob catarrhal hernia ntawm txoj hlab pas qhib ntawm lub diaphragm, catarrhal reflux esophagitis, yaig ntawm lub antrum, mob hnyuv sab nraub qaum. Sij hawm dhau los, muaj mob plab thiab caws pliav tau pom nyob hauv duodenum. Nws tau kho nws tus kheej ntawm qhov chaw nyob. Xws li tas li (yuav luag txhua hnub) Kuv tau noj Omeprazole, uas tau pab me ntsis thiab rau lub sijhawm luv luv (qee zaum kuv yuav tsum tau noj ntau lub tshuaj ib zaug kom txo qhov mob plawv mob siab). Kev kho lub plawv dhia yeej tsis nres ib zaug li. Nyob ib ncig ntawm tib lub sijhawm, Kuv muaj vasomotor rhinitis. Tsis muaj ib yam pa. Rau lub hom phiaj kuv txhaj tshuaj tsuag tshuaj hormonal. Yuav luag tsis pab. Tau li ntawm 4-5 xyoos tas los, nws tau zoo tu qab heev (ntawm qhov loj me 46 txog 56-58). Los ntawm cov plaub hau sai sai tsis muaj dab tsi yuav sab laug ntawm txhua. Ob xyoos dhau los ob xyoos, nws pib txhawm chim. Muaj ib tug nres ntawm txhawm chim hais tias kuv xiav-violet. Rau qee qhov laj thawj, tus kws kho mob tau sau ntawv kom siv cov tshuaj tua kab mob penicillin, uas kuv ib txwm muaj qhov tsis haum ib yam li Quincke's edema (Kuv ceeb toom). Tau ntev kuv tau kho qhov ua xua nrog cov tshuaj thiab cov kua me me nrog cov tshuaj hormonal (hauv tsev kho mob). Xyoo dhau los pib nkees ntau thiab ntau yam. Hemoglobin nqis mus rau 88, protein rau 72-73. Kuv raug kho los ntawm hematologist: mob ntshav qis me ntsis, mob plawv plawv. (Yuam kom coj sorbifer. Maltofer lub lim ntshav ntawm cev nqaij daim tawv txwv tsis pub, nws tsis kho). Tus kws kho mob hlwb tau tam sim no tau tsa Pariet. Kuv yeej tau ua xyem xyav tias yus yuav tsum haus ib cov tshuaj uas kim kim li ntawd. Tab sis kuv nyeem cov ntaub ntawv ntawm koj lub xaib hais txog qhov ua tau zoo ntawm cov tshuaj thiab cov teeb meem los ntawm lawv, Kuv pom tias tsuas yog nws tuaj yeem pab kuv xwb. Thiab tag nrho cov teeb meem nyob rau hauv daim ntawv ntawm ua pa luv luv, bronchospasm, nce phaus, plaub hau poob, tsis pom kev zoo (Kuv pib pom tsis zoo hauv tsom iav thiab tsis tsom iav), zoo heev tsis muaj zog thiab ntau ntxiv, koj yuav tsis piav qhia txhua yam ntawm Omeprazole. Kuv tsis tau xav txog tias Omeprazole tuaj yeem tsim kev puas tsuaj ntau dua qhov zoo, thiab tsuas yog txaus ntshai rau kuv txoj kev noj qab haus huv, nws zoo li rau kuv yog li muaj kev ntseeg siab thiab, tseem ceeb, pheej yig.

Kuv puas yuav ua tsis taus pa ib txwm tam sim no, yuav pom kuv lub zeem muag dua, puas yuav ua rau kuv lub cev hnyav dua qub? (Kev kuaj mob fab tsis zoo, Kuv nrhiav tsis tau cov lus qhia rau tus neeg ntsuas ntsws). Ib tug neeg txawj teb kuv, tawm tswv yim dab tsi txog qhov no yuav ua li cas?

Rabeprazole thiab omeprazole yog los ntawm tib pab pawg, yog li ntawd lawv cov kev mob tshwm sim zoo sib xws. Tsis txhob cia siab rau qhov kev txhim kho dhau dhau.

Hawb pob thiab vasomotor rhinitis feem ntau yuav cuam tshuam nrog cov kua qaub ua kom rov qab los ntawm txoj hlab pas mus rau lub ntsws. Nov yog qhov sib txuam nrog.

Vim li cas omeprazole tsis pab zoo yog tsis paub meej. Kom paub tseeb tseeb, tus ntsuas dej pH txhua hnub yuav tsum ntsuas.

Txawm li cas los xij, Kuv paub tseeb tias omeprazole ua, thiab qhov tseeb ua rau koj cov teeb meem yog hiatal hernia. Tib qho kev xaiv los tshem tawm nws (thiab tom qab ntawd lub neej feem ntau yuav pib txhim kho) yog kev phais mob. Koj qhov xwm txheej yog qee qhov tsis saib xyuas, yog li npaj ua ntej kev phais mob yuav tsum tau (nce hemoglobin, thiab lwm yam). Txawm li cas los xij, koj yuav tsum tau ua haujlwm ntawm, vim hais tias ntxiv nws yuav tseem phem tshaj.

O.N. Minushkin, L.V. Maslovsky, Yu.N. Loshchinina, N.Yu. Anikina,
Lub Chaw Kawm Txuj Ci thiab Kev Tshawb Fawb ntawm Kev Tshawb Fawb ntawm Thawj Tswj Hwm ntawm Lavxias

Hauv cov tebchaws tau tsim, nyob rau xyoo tsis ntev los no, qhov kev tshwm sim ntawm txoj hlab ntsws tsis ua haujlwm (GERD) tau hloov zuj zus. GERD cov tsos mob tau ntsib txhua hnub txog li 10% ntawm cov neeg, txhua lub lim tiam tau 30%, thiab cov hli tau 50%. Cov qauv rau kev nce ntxiv ntawm qhov tshwm sim ntawm GERD yog lub hauv paus rau kev tshaj tawm ntawm 6th European Gastroenterological Lub Limtaus cov lus "Lub xyoo pua XX - lub hnub nyoog mob peptic, XXI - hnub nyoog GERD".

Cov kev tshawb fawb hauv Lavxias ua raws li ib feem ntawm WHO MONICA qhov kev pabcuam hauv Novosibirsk qhia pom tias muaj qhov sib piv ntawm GERD piv rau cov ntaub ntawv saum toj no. Kev kub siab tau dhau los ntawm 61.7% ntawm tus txiv neej thiab 63.6% ntawm poj niam, nrog 10.3% thiab 15.1% feem ntau lossis tas li (5). Cov txiaj ntsig ntawm peb tus kheej txoj kev tshawb nrhiav, raws li kev rov tshuaj dua ntawm kev tshawb pom thawj zaug ntawm kev mob qog nqaij hlav ntawm 5107 tus neeg mob txoj hnyuv hauv lub sijhawm 5-xyoo, tau qhia tias muaj kev cuam tshuam endoscopic ntawm tus mob reflux esophagitis tau kuaj pom ntawm 1419 tus neeg mob (27.8%), ntawm uas 880 txiv neej (28.8%) thiab 539 poj niam (26.3%) (qhov feem pua yog muab ntawm tag nrho cov txiv neej lossis poj niam). Catarrhal esophagitis tau kuaj pom nyob hauv 890 tus neeg mob (17.4%) - 538 tus txiv neej (17.8%) thiab 352 tus poj niam (17.2%). Kev mob hlab pas - nyob rau hauv 529 soj ntsuam (10.4%) - 342 tus txiv neej (11,2%) thiab 187 tus poj niam (9.1%).

Kev kho mob GERD kom tsim nyog yog tsim nyog, vim tias tus kab mob no cuam tshuam lub neej zoo ntawm cov neeg mob, thiab lub caij nyoog ntev thiab kev loj hlob ntawm txoj hlab pas tuaj yeem ua rau txoj kev loj hlob ntawm nruj, Barrett txoj hlab nqos mov thiab txoj hlab ntsws mob cancer.

Kev Kho Mob ntawm GERD suav nrog cov lus pom zoo rau hloov tus neeg mob txoj kev ua neej thiab kev siv tshuaj kho (2). Hauv cov neeg mob uas tsis muaj tus mob esophagitis, lub hom phiaj ntawm kev kho mob yog los tshem tawm cov tsos mob cuam tshuam nrog cov kua qaub ua kom lub ntsej muag (kub siab, qee zaum mob tom qab sternum) thiab txhim kho lub neej zoo. Nyob rau ntawm qhov muaj teeb meem esophagitis, kev kho mob kuj tseem ua kom tiv thaiv kev txhim kho ntawm cov teeb meem xws li txoj hlab pas ua pa lossis epithelial metaplasia (Barrett's esophagus).

Hauv txhua qhov GERD kev hloov pauv, kev kho thaum xub thawj suav nrog kev teeb tsa rau kev kho tsis yog tshuaj (nce lub taub hau kawg hauv txaj, poob phaus, noj kev txwv kev noj haus, thiab lwm yam) thiab noj tshuaj antacids. Yog tias cov tsos mob mob siab rau cov keeb kwm yav dhau los no, kev kho tshuaj kho mob txuas rau 2-4 lub lis piam. Qhov kev xaiv pib siv ntau tshaj plaws yog kev tiv thaiv cov twj tso kua mis. Tam sim no muaj cov ntaub ntawv qhia kwv yees li kev kuaj mob ntau yam ntawm ntau cov neeg sawv cev ntawm pawg tshuaj no (omeprazole, lanzoprazole, pantoprazole, rabeprazole thiab esomeprazole) (9, 11). Tus nab npawb ntawm cov kev tshawb fawb qhia qee qhov muaj txiaj ntsig zoo ntawm esomeprazole dhau ntawm omeprazole nyob rau hauv kev ntsuas ntawm kev tshem tawm kev mob plab thiab tus nqi ntawm qhov tshwm sim ntawm cov nyhuv (10). Txawm li cas los xij, qhov sib txawv uas tau txais yuav yog vim ntau qhov sib txawv ntawm cov tshuaj (40 mg thiab 20 mg, feem).

Tus kheej kev paub txog kev kho mob rau 115 tus neeg mob (77 tus txiv neej, 38 tus poj niam, hnub nyoog nruab nrab 45.1 ± 1.2 xyoo) GERD 0-4 degrees omeprazole, esomeprazole, rabeprazole hauv cov qauv tshuaj rau 4 lub lis piam tsom siab saib xyuas cov neeg mob siab thiab endoscopic ntawm txhua qhov kev kawm kev npaj (6, 7, 8).

Kev ua zog ntawm cov chaw kuaj mob thiab cov duab endoscopic tau nthuav tawm hauv cov duab 1 thiab 2.

Tus naj npawb ntawm cov neeg mob uas ua tiav ntawm kev kho yaig tom qab 4 lub lim tiam ntawm kev kho mob nrog ntau yam PPIs, nyob ntawm seb cov qib ntawm zias plas paug

Feem pua ntawm cov neeg mob nrog ua tiav kev kub siab tom qab 4 lub lis piam ntawm kev kho mob nrog ntau yam PPI

Cov ntaub ntawv tshaj tawm qhia txog qhov ua tau zoo ntawm txhua cov tshuaj siv hauv kev kho mob ntawm txoj hlab pas, tsis muaj qhov sib txawv ntawm cov neeg mob nrog kev kho kom zoo ntawm kev yaig tom qab 4 lub lis piam ntawm kev kho mob nrog Omez, Pariet lossis Nexium. Ib qho qauv zoo sib xws tau pom nrog hais txog kev daws mob ntawm cov tsos mob, tshwj xeeb ua rau kev kub siab. Rooj ntawv 2 qhia tias Omez muaj qee qhov zoo.

Txhawm rau ntsuas qhov ua tau zoo ntawm ntau hom kev tswj kho txij nkawm, Omez tau siv. Ib qho ntawm cov laj thawj rau qhov kev xaiv no yog tias Omez yog ib qho ntawm cov pheej yig tshaj tawm cov twj tso kua mis tshuaj tiv thaiv nyob rau hauv Russia thiab tsis qis dua qhov nws cov hauj lwm zoo rau lwm cov tshuaj tiv thaiv proton twj tso kua mis ntawm cov khw muag tshuaj Lavxias.

Peb tau soj ntsuam qhov kev ua tau zoo ntawm 4 hom kev tswj kev kho nrog Omez (omeprazole) ntawm koob tshuaj 20 mg rau 12 lub hlis rau cov neeg mob GERD 0 thiab 1 tbsp. raws li kev ua tiav chaw kuaj mob thiab kev pom zoo nrog kev kho mob:
1) noj Omez ntawm koob tshuaj 20 mg / hnub ib hnub (1 pawg - 20 tus neeg mob),
2) noj Omez ntawm koob tshuaj 20 mg / hnub txhua lwm hnub (pawg 2 - 20 tus neeg),
3) noj Omez nyob rau hauv ib koob tshuaj 20 mg nyob rau hauv "xav tau" hom: 20 mg / hnub nrog kub siab (pab pawg 3 - 20 tus neeg mob),
4) noj Omez nyob rau hauv ib koob tshuaj 20 mg nyob rau hauv hom "lis xaus": 20 mg / hnub rau hnub Friday, Saturday thiab hnub Sunday (pab pawg 4 - 15 tus neeg mob),
5) pab pawg tswj hwm - cov neeg mob uas tsis tau txais kev kho kom zoo (pawg 5 - 30 tus neeg mob).

Tag nrho ntawm 105 tus neeg mob tau lees rau txoj kev tshawb no: 62 tus txiv neej (59%) thiab 43 tus poj niam (41%). Txhua tus neeg mob tau koom nrog European haiv neeg. Cov yam ntxwv ntawm pawg tau nthuav tawm hauv lub rooj 3.

Cov yam ntxwv ntawm cov neeg mob kawm

Ua ntej muab tso rau hauv txoj kev tshawb fawb, txhua tus neeg mob tau kuaj pom tseeb (Cov Lus 4), qhov mob hnyav ntawm cov tsos mob thiab lub neej zoo tau raug ntsuas. Kev kuaj mob endoscopic soj ntsuam tau ua tiav txhua 3 lub hlis. Kev ntsuas kev ntsuas ntawm GERD hauv kev ntsuas qhov tseeb tau ua raws li kev faib tawm ntawm Savary-Miller hauv kev hloov kho ntawm Carisson et al. Cov neeg mob tau khaws cia ib daim ntawv qhia hnub nyob rau hauv uas lawv tau txheeb xyuas qhov sib txawv ntawm cov tsos mob ntawm Likert nplai, thiab siv qhov sib piv ntawm daim duab (VAS) tau siv los ntsuas lub neej zoo. Cov neeg mob tau txais kev kho mob ntawm PPI nyob rau hauv ib qho kev txhaj tshuaj kom txog thaum kho qhov kev pom tseeb kev kho mob tau ua tiav, tom qab ntawd lawv tau raug kho kev saib xyuas kev kho mob nrog Omez hauv ib qho kev tswj hwm.

Kev faib khoom ntawm cov neeg mob nyob rau hauv cov pab pawg nyob ntawm qhov degree GERD

Cov pab pawg	GERD kawm hauv endoscopy
Cov pab pawg	GERD 0 qib	GERD 1 degree
Pawg 1 (n = 20)	9 (45%)	11 (55%)
Pawg 2 (n = 20)	8 (40%)	12 (60%)
Pawg 3 (n = 20)	11 (55%)	9 (45%)
Pawg 4 (n = 15)	7 (46,6%)	8 (53,3%)
Pawg 5 (n = 30)	13 (43,3%)	17 (56,6%)

Kev faib tawm ntawm cov pab pawg tau Random. Cov neeg mob hauv txhua pawg tau sib piv hauv lub hnub nyoog, lub caij nyoog ntawm tus kab mob, lub cev loj hauv lub cev (BMI), thiab tus lej ntawm lwm cov tsos mob (cov lus qhia 5).

Cov yam ntxwv ntawm cov neeg mob ntawm cov pab pawg tau kawm

Kev ntsuas ntawm qhov ua tau ntawm kev saib xyuas kev kho kom raug raws li kev pom tseeb hauv qab no qhia cov hauv qab no. Hauv cov neeg mob ntawm cov pab pawg 1 thiab 2, kev rov ua dua ntawm cov hlab pas es tsis pom. Hauv cov neeg mob ntawm pab pawg 3 nrog 1 degree GERD, tus mob rov huam mob tau pom tom qab 3 thiab 6 lub hlis hauv 44,4% ntawm tus neeg mob. Hauv pawg 4 cov neeg mob, qhov tshwm sim ntawm daim tawv nqaij nrog kev xyeem qhov tseeb tau kuaj hauv 7 tus neeg mob, uas yog 87.5%. Hauv cov neeg mob ntawm pawg tswj hwm, rov qab pom tau pom hauv 100% ntawm cov neeg mob 6 lub hlis tom qab qhov kawg ntawm kev kho.

Kev ntsuas qhov ua tau ntawm kev ua haujlwm ntawm kev saib xyuas zoo raws li cov ntaub ntawv tshawb fawb

Kev hloov ntawm qhov nquag ntawm lub siab kub siab thaum kho kev kho mob hauv cov pab pawg sib txawv tau nthuav tawm hauv Daim Duab 1-4.

Daim duab 1 Kev ua haujlwm ntawm cov tsos mob hauv cov neeg mob ntawm pawg 1 (Omez 20 mg txhua hnub)

Daim duab 2 Kev loj hlob ntawm cov tsos mob hauv cov neeg mob ntawm pab pawg 2 (Omez 20 mg txhua txhua lwm hnub)