Los ntawm dab tsi Cocarboxylase: cov lus qhia rau kev siv
Coenzyme tsim nyob rau hauv lub cev los ntawm thiamine. Nws muaj cov txiaj ntsig metabolic, ua kom cov nqaij metabolism. Hauv lub cev, nws yog phosphorylated los ua mono-, di- thiab triphosphoric esters, cocarboxylase yog ib feem ntawm cov enzymes uas catalyze carboxylation thiab decarboxylation ntawm keto acids, pyruvic acid, txhawb kev tsim ntawm acetyl coenzyme A, uas txiav txim siab nws koom nrog hauv metabolism metabolism. Kev koom tes hauv lub voj voog pentose yog ncaj qha txhawb nqa kev coj ua ntawm nucleic acids, proteins thiab lipids.
Txhim kho cov kua nplaum txhaws, trophic cov hlab ntaws, pab ua kom lub luag haujlwm ntawm cov hlab plawv.
Cocarboxylase deficiency ua rau muaj kev nce qib ntawm pyruvic thiab lactic acids hauv cov ntshav, uas ua rau cov kab mob acidosis thiab acidic coma.
Daim ntawv tso tawm
Cov tshuaj hnyav: dej d / i - 2 ml.
50 mg - ampoules (5) ua tiav nrog cov kuab tshuaj (amp. - 5 pcs.) - ntim cov duab los qhia.
Cov neeg laus tau muab iv lossis iv. Qhov hno yog 50-200 mg / hnub. Hauv cov ntshav qab zib mellitus (acidosis, coma), qhov koob tshuaj txhua hnub tuaj yeem yog 0.1-1 g. Qhov nquag thiab lub sijhawm siv yog nyob ntawm cov ntsuas.
Rau cov menyuam yaus - hauv / m, hauv / hauv (poob lossis ntws), rau cov menyuam yug tshiab - sublingually. Cov menyuam muaj txog 3 hlis - 25 mg / hnub, txij li 4 hlis txog 7 xyoo - 25-50 mg / hnub, hnub nyoog 8 txog 18 xyoo - 50-100 mg / hnub. Lub sijhawm tiv thaiv yog los ntawm 3-7 mus rau 15 hnub.
Sab sij huam
Tej zaum: kev ua xua (urticaria, khaus).
Nrog / / kev taw qhia: hyperemia, khaus khaus, o ntawm qhov chaw txhaj tshuaj yog ua tau.
Hauv kev sib xyaw ua ke: kev mob metabolic acidosis, acidosis hauv hyperglycemic coma, acidosis hauv kev ua pa thiab lub ntsws tsis ua haujlwm, mob plawv tsis ua haujlwm, mob plawv, tsis txaus ntseeg lub plawv tsis txaus, mob plawv tsis txaus, myocardial infarction, post-infarction cardiosclerosis, mob siab thiab / lossis lub raum tsis ua haujlwm, mob ntshav qab zib thiab ntev , intoxication nrog mob plawv glycosides thiab barbiturates, kis kab mob sib kis (mob qa ntshav, caws pliav, kub taub hau, paratyphoid kub taub hau), neuralgia, ntau yam sclerosis, peripheral neuritis.
Cov no yog cov siv tau tsis siv tshuaj kiag li lawm.
Hauv cov koob txhaj tshuaj sib txawv thiab txhua qhov hauv nws tus kheej qhov chaw
ob qho tib si raug txhaj tshuaj nkaus xwb intramuscularly - nyob rau hauv lub nroog Yeiuxalees, kev daws teeb meem nws tus kheej tsis tas yuav tsum tau xeb
thiab ib tug neeg xav tau txais lawv lub hlwb tawm! KKB muaj kev daws teeb meem! nws yog hmoov. tshuaj rau hnub sib txawv, nkaug rau hauv cov leeg nqaij! piv txwv li: thawj hnub yog kkb, thib ob yog atf
Puas yog Thiotriazolinum thiab Cocarboxylase xav tau chob nrog kev hloov pauv hauv myocardium?
Nyob zoo thaum tav su, Nyob zoo Victoria Yuryevna! Tau ntev, kuv tau ntxhov siab vim tsis xis nyob hauv thaj chaw hauv lub plawv (nyem, tingling, hlawv, palpitations nrawm nce mus txog 100, nqaj ntawm txhais tes tau pib loog thaum pw tsaug zog lossis khoov ncaj, thiab tom qab ob txhais ceg), tom qab ECG, tus kws kho mob hais tias muaj qee yam tsis thim rov qab ntawm lub siab, koj tsuas yog xav haus cov sedatives. 6 lub hlis dhau los Kuv tau nyob hauv chav kho mob thiab, tom qab ECG, Kuv tau muab qhov xaus "diffuse myocardial hloov" thiab raug qhia kom txhaj 1 ampoule ntawm ATP thiab Carboxylase ib zaug ib hnub rau 10 hnub, txhawm rau txhim kho metabolism, thiab tom qab ntawd hno nws nrog tib chav Thiotriazolin ua kom lub plawv muaj zog, tsim kom muaj cov pa oxygen rau lub plawv, kho lub plawv dhia, thiab tiv thaiv kom txhob mob stroke. Tab sis, tom qab 1 ampoule, kuv qhov mob ntawm trigeminal cov hlab ntaws tuaj, tab sis kuv tau qhia tias feem ntau yog kev kee thiab cov tshuaj no tsis tuaj yeem ua rau muaj kev cuam tshuam. Thiab yog li kuv txawm li cas los chob twb tau 5 hnub (5 ampoules), thiab tam sim no tau nyeem ntau cov ntaub ntawv, Kuv muaj kev ua xyem xyav seb kuv puas xav tau cov tshuaj no? Ua tsaug rau koj ua ntej rau koj kev teb!
Nyob zoo. Cov cim ntawm kev hloov pauv txawv ntawm myocardium raws li ECG tsis yog kev kuaj mob, tuaj yeem tshwm sim hauv ntau yam kabmob thiab xav tau kev kuaj mob kom paub tseeb dua. Hais txog kev teem caij - tsis muaj ib yam txhaum rau lawv. Xws li kev kho mob metabolic yog ob qho tib si rau cov kab mob uas twb muaj lawm thiab rau kev tiv thaiv. Txoj kev kho yuav tsis tuaj yeem ua kom mob rau cov mob. Ib qho ntxiv yog tias thaum muaj cov kab mob plawv no txoj kev kawm tsis txaus, yog li kev soj ntsuam txuas mus ntxiv.
Kev mob plab acidosis
Nyob rau tag nrho lub neej, muaj coob leej ntau yam ntawm cov acids yog tsim nyob rau hauv tib neeg lub cev. Nws tau tshem ntawm lawv cov dhau los ntawm cov zis, tawm hws thiab ua pa nyuaj. Qhov no tshwm sim yog tias cov metabolism tsis tsis txaus, vim hais tias txwv tsis pub lawv yuav nthuav tawm hauv cov ntshav thiab cuam tshuam tsis zoo rau cov nqaij sib txuas thiab cov hlab ntsha ntawm tus neeg. Tus txheej txheem no hu ua metabolic acidosis thiab feem ntau tshwm sim thaum lub cev raug kev txom nyem los ntawm kev tsis muaj vitamin B1. Cov kab mob no ua rau muaj kev phom sij: ntxiv ntshav coagulation, myocardial infarction, peripheral thrombosis, hyperglycemic coma thiab tuag. Vim li no, cov kws tshwj xeeb uas tau tshawb pom tus neeg mob uas muaj teeb meem nrog acid-base tshuav nyiaj li cas tau sau daim ntawv yuav ntawm tus neeg muag tshuaj "Cocarboxylase". Cov lus qhia rau kev siv yog nthuav tawm hauv qab no.
Pharmacological muaj peev xwm
Cocarboxylase yog lub cev tsis muaj protein ntau ua kom ncaj qha rau cov txheej txheem neuro-reflex ntawm lub cev, txo qis cov kab mob lactic, pyruvic thiab alpha-ketoglutaric acids.
Nws cov txiaj ntsig zoo yog tsom rau cov metabolism hauv carbohydrate thiab muab cov ntaub so ntswg nrog lub zog. Cocarboxylase deficiency ua rau cov piam thaj tsis zoo, kev ua kom lub plawv mob, thiab cov hlab ntsha hauv lub cev cov metabolism. Qhov no tuaj yeem ua rau qhov tseeb tias ib tus neeg yuav muaj kev txaus ntshai rau cov kab mob xws li acidosis, mob ntshav qab zib mellitus, neurocircular dystonia, lub plawv pathologies, thiab lwm yam. Hauv paus, cov tshuaj "Cocarboxylase" normalizes acid-puag thiab lub zog metabolism. Qhov no, nyeg, muaj kev cuam tshuam rau cov ua antitoxic thiab anti-ischemic.
"Cocarboxylase": cov lus qhia rau kev siv thiab cim
Cov tshuaj yog tshuaj rau cov neeg mob uas yuav tsum kho cov metabolism hauv lub sijhawm ua pa, mob ntshav siab, mob plawv thiab lub raum tsis ua haujlwm. Kev mob ntshav siab, tiv thaiv ua ntej thiab tom qab kis mob, uas tuaj yeem tshwm sim vim muaj cov kua qaub ntau hauv cov ntshav, kev npaj coenzyme "Cocarboxylase", cov qauv tshuaj kuj tuaj yeem daws cov teeb meem zoo sib xws, pab ua kom ib txwm muaj rau tus neeg. Feem ntau nws yog kho rau tib neeg kev txom nyem los ntawm kev haus cawv ntev thiab lom ntawm ib daim ntawv twg, suav nrog kev noj tshuaj.
Cov tshuaj "Cocarboxylase", cov lus qhia rau kev siv uas yog hauv qab no, yog tsim rau kev kis kab mob:
Peripheral neuritis thiab ntau yam sclerosis tsis muaj qhov tshwj xeeb. Txawm hais tias hauv kev xyaum tsiaj, tshuaj tau pom nws qhov chaw. Nws yog siv thaum cev xeeb tub yog tias muaj mob toxicosis lossis me nyuam hauv plab hypoxia.
"Cocarboxylase" yog cov ampoule nrog cov hmoov uas yuav siv los txhaj rau tus neeg mob. Rau cov menyuam yaus, cov tshuaj tau txais koob tshuaj intramuscularly, subcutaneously, lossis qee kis sublingually hauv tus nplaig. Cov tshuaj "Cocarboxylase" yog siv rau cov tshuaj rau cov neeg laus ib zaug ib hnub.
Cov menyuam yaus hnub nyoog qis dua 8 xyoo tau txhaj nrog 25 mg ntawm cov tshuaj "Cocarboxylase". Cov lus qhia rau siv rau cov laus thiab menyuam yaus tom qab yim xyoo yog txawv me ntsis - mg. Lub sijhawm sijhawm ntawm kev kho mob nrog kev kho mob yog teem los ntawm tus kws kho mob tshwj xeeb rau txhua tus neeg mob. Nws tag nrho yog nyob ntawm qhov degree thiab tsis saib xyuas ntawm tus kab mob.
"Cocarboxylase": taw qhia thaum cev xeeb tub
Tus me nyuam hauv lub cev ntawm tus poj niam noj qab haus huv txhua tus tau txais tag nrho cov vitamins thiab cov zaub mov tsim nyog rau kev loj hlob. Tab sis yog tias tus poj niam cev xeeb tub muaj cov teeb meem loj, xws li mob toxicosis hnyav nyob rau lub hli dhau los ntawm kev xeeb tub, mob dab noj, tsis muaj zog thauj thiamine, mob nriaj, ces Cocarboxylase tau raug tshaj tawm rau leej niam ua ntej muaj qhov tseeb ntawm qhov no lossis qhov mob ntawd tau tsim. Tsis tas li, cov tshuaj no tau pom zoo rau kev siv los ntawm cov poj niam cev xeeb tub muaj kev mob ntshav qab zib.
Sab nraud thiab contraindications
Muaj kev xyaum tsis muaj kev phiv los ntawm kev siv tshuaj, tshwj tsis yog kev haus luam yeeb rau cov tshuaj yeeb dej caw nws tus kheej (cocarboxylase). Cov lus qhia rau kev siv tsom mus rau qhov tseeb tias tom qab kev qhia txog cov tshuaj no, tsis muaj kev cuam tshuam loj heev tshwm sim.
Cocarboxylase yog cov tshuaj zoo heev, tab sis ua ntej siv nws hauv kev kho mob, nws yog qhov yuav tsum tau sab laj nrog koj tus kws kho mob.
Cocarboxylase-Forte - nws yog dab tsi thiab nws txawv li cas?
Coob tus neeg uas tau mob dhau los ua ib hom kab mob tshwj xeeb thaum mus rau hauv cov khw muag tshuaj tau thov kom muab qee yam zoo, tab sis tsis tas yuav hno. Tsis muaj dab tsi coj txawv txawv hauv qhov no, vim tias kev txhaj tshuaj ib txwm yog ib qho kev siv ntxiv thiab tsis tsim nyog. Tsis tas li ntawd, qhov no yooj yim heev, vim tias tsis yog txhua tus tuaj yeem muab kev txhaj tshuaj rau tom tsev lossis nug cov neeg txheeb ze txog nws. Tom qab tag nrho, yog tias nws ua txhaum, tom qab ntawd tsis xis nyob thiab tsis xis nyob hauv thaj chaw txhaj tshuaj yog qhov lav. Yog li no, cov yeeb tshuaj "Cocarboxylase-Forte" hauv cov ntsiav tshuaj tau tsim.
Cocarboxylase tsis yog cov tshuaj tiv thaiv nkaus xwb uas yog ib feem ntawm qhov tshuaj. Nws tseem muaj glycerol amino acids thiab magnesium ions. Lawv txhim kho cov kev ua ntawm cocarboxylase. Magnesium pab txhim kho kev nqus thiab cov metabolism, thiab glycerin muab cov nyhuv me, txhim kho thiab ua kom tsaug zog zoo dua.
Cov tshuaj yeeb tshuaj "Cocarboxylase", tshuaj xyuas cov uas tau zoo heev, tsis muaj qhov sib txawv tshwj xeeb nrog "Cocarboxylase-Forte" hauv kev hais txog kev nqis tes ua pharmacological. Nws kuj yog siv nyab xeeb rau kev ua txhaum ntawm cov kua qaub-nyob tus lej tshuav nyiaj thiab rau kev tiv thaiv ntawm cov teeb meem ntshav qab zib.
Cocarboxylase Forte: Kev Tshuaj Ntsuam Xyuas
Cov kws tshaj lij hais tias Cocarboxylase-Forte siv tau zoo heev rau kev siv ntau txoj hauv kev kho mob hauv cov neeg mob ntshav qab zib mellitus, mob plawv, mob plawv, dystonia, kev mob plab tsis txaus, thiab ntxiv rau kev tiv thaiv ntawm cov teeb meem hauv cov hlab plawv.
Cocarboxylase Forte: Cov txiaj ntsig
Cov tshuaj no tam sim no feem ntau yuav ntau dua li Cocarboxylase rau kev txhaj tshuaj, vim qhov zoo ntawm kev siv tsis muaj qhov tsis xis nyob thiab tsis muaj tus nqi ntxiv nyob rau hauv daim ntawv ntawm cov koob txhaj tshuaj, dej rau txhaj tshuaj, thiab lwm yam.
Qhov no tseem ceeb heev rau cov menyuam yaus uas raug cov kab mob saum toj no. Tom qab tag nrho, qhov tseeb hais tias lawv tau muaj kev mob nkeeg zoo li no, thiab yog li nws ua rau lawv muaj teeb meem ntau, thiab nws yog qhov tseem ceeb heev los muab rau lawv yam tsawg kawg yog kev kho mob yooj yim yam tsis siv cov koob.
Txoj kev ntawm kev siv cov tshuaj thiab nws cov contraindications
"Cocarboxylase-Forte" tsis tau hais rau cov neeg uas muaj kev tiv thaiv tsis txaus siab rau cov khoom siv. Tsis tas li, nws tsis raug pom zoo rau cov poj niam cev xeeb tub. Cov tshuaj tsis raug cai rau cov menyuam yaus uas tsis tau txog hnub nyoog kaum ob xyoos.
Cov neeg mob ntshav qab zib noj Cocarboxylase Forte yuav tsum saib xyuas lawv cov ntshav qab zib txhua hnub.
Qhov ntau npaum li cas yog ib txwm teeb los ntawm tus kws kho mob tuaj koom. Cov neeg laus thiab menyuam yaus hnub nyoog kaum ob xyoos, noj ib ntsiav tshuaj hauv qab nplaig kom txog thaum yaj tag, 3-4 zaug ib hnub. Nws tseem muab rau qhov ncauj noj 15 feeb ua ntej noj mov 3-4 zaug ib hnub, koj yuav tsum haus ib ntsiav tshuaj nrog dej me me. Lub sij hawm ntawm kev kho mob feem ntau kav tsis pub dhau ib hlis.
"Cocarboxylase": taw qhia rau siv
Kev siv ntawm Cocarboxylase txo qhov kev cia siab ntawm pyruvic acid thiab lactic acid, txhim kho cov kua nplaum ua haujlwm, muaj qhov cuam tshuam zoo ntawm trophic cov hlab ntaws, thiab cov haujlwm ua haujlwm ntawm lub plawv. Yog tias lub cev tiv thaiv tsis txaus hauv cov tshuaj no, qib pyruvic acid hauv cov ntshav nce siab, uas tuaj yeem ua rau txhim kho acidosis.
Kev taw qhia rau kev siv thiab tus nqi
Tus nqi nruab nrab ntawm cocarboxylase hauv ampoules thiab flono rubles. Koj tuaj yeem yuav cocarboxylase hauv cov khw muag tshuaj.
Kev siv cov cocarboxylase thiab cim:
- Ntshav qab zib, metabolism, ua pa acidosis (malfunctions ntawm cov kua qaub-puag hauv lub xeev, lawv pom tias qib pH tsawg thiab hauv cov concentration ntawm bicarbonate hauv qab ib txwm muaj.
- Kev mob ntshav qab zib, hyperglycemia (siab thiab qab zib qis).
- Pathological kev noj qhov chaw nyob rau hauv lub cev, nrog los ntawm kev ua tsis taus pa metabolism. Kab mob ntawm pawg neeg no tuaj yeem yog keeb kwm thiab kis tau. Feem ntau, galactosemia, feem ntau glycogenosis, thiab ntshav qab zib mellitus tau pom.
- Hepatic, ua pa, lub raum, plawv nres. Qhov tseeb txog cov mob voos thiab mob ntev.
- Postinfarction cardiosclerosis - raws li kev tiv thaiv txoj kev kho mob ntawm cov kab mob plawv, hauv ntau yam ntawm no.
- Hepatic tsis meej pem.
- Mob qab zib coma. (Ntau zaus tshwm sim hauv ntshav qab zib los ntawm qhov ua txhaum ntawm cov cai ntawm cov piam thaj hauv ntshav)
- Kev haus cawv ntev ntev thiab qaug cawv kom qaug.
- Tshuaj lom neeg pab pawg ntawm barbiturates, digitalis.
- Paratyphoid, kub taub hau, diphtheria, typhoid fever - raws li txoj kev kho mob.
- Ntau yam sclerosis, mob hlab ntsha hlwb.
- Encephalopathy, hypoxic perinatal, mob ntsws, mob ntsws, mob ntsws, ua tsis taus pa ntawm cov menyuam mos yug tshiab.
- Cov mob uas muaj los ntawm acidosis thiab hypoxia.
Cov lus qhia rau kev siv thiab koob tshuaj
Cov lus qhia rau kev siv cov kev txhaj tshuaj ntawm cocarboxylase thiab hmoov rau kev npaj ntawm kev daws:
- Cocarboxylase yog muab tshuaj subcutaneously, intramuscularly lossis intravenously. Qhov feem ntawm cov tshuaj yog tawm ntawm tus kheej, raws tus anamnesis, kev mob ntawm tus neeg mob thiab mob hnyav ntawm tus kab mob.
- Rau cov laus, cov tshuaj tau muab ib zaug - 50/100 mg. Yog tias tsim nyog, xws li cov ntaub ntawv ntawm kev txhim kho cov mob ntshav qab zib tsis xeev, ib zaug txhua ob rau peb teev. Hauv lub neej yav tom ntej, cov kev kho mob kws kho tau pom zoo txhawb nqa - 50 mg txhua hnub.
- Nrog ruaj khov tsis ua hauj lwm - nruj me ntsis 50 mg ob rau peb zaug txhua hnub, ua ntej noj digitalis npaj. Cov chav kawm ntawm cov txheej txheem yog 24 teev.
- Hauv cov ntshav qab zib mellitus, mg txhua hnub nrog lub sijhawm ntev txog 5-10 hnub, yam tsis tau txiav tseg kev siv tshuaj tiv thaiv kab mob.
- Hauv kev mob ceev rau lub raum lossis lub siab ua haujlwm poob, kub hnyiab, intoxication mg peb zaug ib hnub.
- Nrog rau ntau yam sclerosis thiab peripheral neuritis, 50/100 mg txhua hnub supra.
Cocarboxylase hydrochloride intramuscularly zoo txhawb rau lub plawv
Niaj hnub no, nws ntaus kuv kom sau tshuaj xyuas cov tshuaj. Nws twb yog hmo ntuj hauv vaj, tab sis kuv tsis tuaj yeem cheem txhua yam))).
Lub sijhawm no, kuv yuav qhia koj txog cov tshuaj uas pab ua kom kuv lub siab rov qab los thiab txhawb lub zog ntawm lub cev tom qab yug menyuam. Thaum kuv txhais ko taw nyob ib ncig ntawm lub moos, kev nyuaj siab tom qab, thiab tom qab ntawd muaj ob tus menyuam ib zaug, nws nyuaj heev rau kuv lub cev muaj zog. Yog li no, thaum pib arrhythmia thiab lub cev pib tshee tshee los ntawm tsis muaj kev pw tsaug zog, (tshwj xeeb tshaj yog hmo ntuj nqus cov mis nyuj), Kuv hais kom kuv niam muab kuv txhaj tshuaj Cocarboxylase hydrochloride intramuscularly.
Zoo hmoo, kuv niam muaj kws kho mob thiab txhaj tshuaj, koj tsis tas yuav mus tom tsev kho mob.
Kuv txoj kev kho mob tau yooj yim: ib hnub kuv tau txhaj tshuaj nrog ATP (tseem rau kev txhawb nqa lub plawv).
Hnub ob, Cocarboxylase hydrochloride tau txhaj.
Hloov cov tshuaj no, kuv lub siab tau txais ib hom “vitamins” uas ua rau kuv muaj lub zog saib xyuas cov menyuam nyob ib puag ncig.
Cov pob ntawv muaj 10 fwj ntawm cocarboxylase + 10 lub raj mis ntawm cov kuab tshuaj rau cov thawj coj intramuscular.
Hmoov tsis zoo, Kuv tsis tuaj yeem pom ATF daim duab, vim tias cov kev txhaj tshuaj no dhau lawm. Thiab kuv niam yuav lwm pob khoom ntawm cocarboxylase. Ib feem ntawm cov lus qhia rau kev siv, Kuv yuav ua kom pom hauv daim duab.Tab sis nws meej meej hais tias nrog mob plawv tsis zoo thiab cov zaub mov tsis zoo rau lub cev, koj tuaj yeem hno cov tshuaj no. Kuv twb tau tachycardia lub sijhawm ntawd, txij li thaum kuv tsis tsaug zog ib txwm rau yuav luag ib nrab xyoo. Yog lawm, thiab kuv tus txiv ho tsis pab. Cov txheej txheem ntawm kev siv cov tshuaj no, Kuv tso tawm ua ntu zus mus. Leej twg hlub, koj tuaj yeem nyeem cov cog kev txhaj tshuaj ua ntej siv.
Kuv txoj kev kho mob, kom lub plawv rov qab thiab txhim kho qhov ua tau zoo, yog 20 hnub.
10 hnub ATP npaj + 10 hnub cocarboxylase npaj.
Cov kev txhaj tshuaj yog mob heev, tshwj xeeb yog cocarboxylase. Nws zoo li muv tau tom. Qhov kawg ntawm kev kho mob, Kuv twb quaj los ntawm kev txhaj tshuaj.
Tab sis tom qab ntawd yuav ua li cas kuv lub siab pib ua haujlwm. Tshiab li cas! Arrhythmia, tachycardia tau ploj mus, Kuv xav tias muaj kev nce siab ntawm lub zog thiab lub zog. Kuv tsis tu siab tias txhua qhov no dhau los. Txawm lub voj voog nyob hauv qab lub qhov muag ploj mus))).
Tus nqi ntawm cov tshuaj rau 10 ampoules yog 70 hryvnias, lossis 300 rubles.
Tag nrho cov chav kawm ntawm kev kho mob, nws raug nqi kuv 150 hryvnias (nrog rau ATP).
Kev txhaj tshuaj Cocarboxylase
Ntau lub tuam txhab tshuaj ua lag luam xa tawm Cocarboxylase, uas yog pawg B yooj yim vitamin .Txhua ampoule tuav 0.05 grams ntawm cov khoom tseem ceeb. Tsis tas li ntawd nyob rau hauv pob muaj ib qho ntxiv ampoule nrog kev daws rau diluting hmoov. Cov tshuaj muaj nyob rau hauv cov hmoov rau kev txhaj tshuaj, uas yuav yaj ua ntej tswj hwm ncaj qha. Cov pob muaj 5 lossis 10 ampoules.
Cov chaw muag tshuaj
Cov cuab yeej no muaj cov kev cuam tshuam hauv qab no rau ntawm lub cev:
- coenzyme
- nrog rau sodium thiab cov protein, nws ua kom nrawm carboxylation thiab decarboxylation,
- nrawm nrawm rau qhov tsim ntawm acetyl coenzyme A, uas ua rau kom muaj qhov tsis tu ncua ntawm cov metabolism hauv cov pluas (metabolism).
Cov Tshuaj Hauv Tshuaj
Nrog rau cov kev tswj hwm hauv tsoomfwv, cov tshuaj tiv thaiv yog nrawm thiab ua kom tiav rau feem ntau ntawm txoj hnyuv thiab duodenum. Tsuas yog 11 teev tom qab siv, cocarboxylase yog tshem tawm ntawm lub cev. Thaum lub sijhawm kawm txog cov tshuaj, tuaj yeem nrhiav pom tias nws muaj nyob hauv txhua daim ntaub so ntswg, thiab tshwj xeeb ntau hauv nws lub siab, lub siab thiab lub hlwb.
Cocarboxylase pab cov piam thaj kom nqus tau thiab ua haujlwm zoo rau CCC plab hnyuv siab raum. Tsis tas li, cov khoom tseem ceeb pab txhim kho cov ntaub so ntswg kev noj haus. Nws qhov tsis txaus ntseeg provokes tsub zuj zuj ntawm cov acids, thaum acidosis tsim thiab nws lub txim yog acidotic coma. Feem ntau cov feem ntau, Cocarboxylase raug pom zoo nyob rau hauv lub xub ntiag ntawm pathologies thaum lub sij hawm ua ntu zus uas muaj qhov tsis txaus endogenous.
Cov Tshuaj Pharmacokinetics
Thaum nws nkag mus rau hauv cov ntshav, qhov tseem ceeb ntawm cov tshuaj raug khaws los ntawm cov ntshav liab thiab kis mus thoob lub cev hauv daim ntawv ntawm thiamine diphosphate. Kev zom cov zaub mov tshwm sim hauv daim siab, thiab cov tshuaj tau tawm hauv qhov siv lub raum nrog zis.
Cov kws kho mob sau ntawv rau Cocarboxylase thaum tseem muaj kab mob hauv qab no:
- acidosis ntawm ntshav qab zib, cov ntaub ntawv ntawm metabolic thiab ua pa,
- lub plawv tsis ua hauj lwm
- raum tsis ua hauj lwm zoo,
- teeb meem ua pa
- cardiosclerosis uas tau tshwm sim tom qab lub plawv nres,
- metabolic mob ntawm carbohydrates,
- plawv nres
- lub siab tsis ruaj ntseg,
- mob plawv plawv, uas tshwm sim hauv ib daim ntawv uas mob ntev,
- coma mob ntshav qab zib thiab mob hepatic,
- haus cawv lom thiab nws lub txim,
- muaj cov keeb kwm ntawm cov neeg quav dej quav cawv,
- ntau yam sclerosis
- ntau yam kabmob sib kis
- sepsis tom qab los ntawm hypoxia thiab acidosis.
Cov Yuav Tsum Tau Ua
- Siab rhiab heev rau cov tshuaj.
- Kev Hypovitaminosis Vitamin B1.
- Vitamin B1 tsis muaj peev xwm.
Thaum cev xeeb tub thiab menyuam yaus
Rau cov menyuam yaus, cov tshuaj yog tau txais tshuaj intramuscularly lossis subcutaneously, tshwj tsis yog rau cov menyuam tshiab. Cov tshuaj yog muab sublingually rau lawv.
Cocarboxylase hydrochloride intramuscularly zoo txhawb rau lub plawv
Niaj hnub no, nws ntaus kuv kom sau tshuaj xyuas cov tshuaj. Nws twb yog hmo ntuj hauv vaj, tab sis kuv tsis tuaj yeem cheem txhua yam))).
Lub sijhawm no, kuv yuav qhia koj txog cov tshuaj uas pab ua kom kuv lub siab rov qab los thiab txhawb lub zog ntawm lub cev tom qab yug menyuam. Thaum kuv txhais ko taw nyob ib ncig ntawm lub moos, kev nyuaj siab tom qab, thiab tom qab ntawd muaj ob tus menyuam ib zaug, nws nyuaj heev rau kuv lub cev muaj zog. Yog li no, thaum pib arrhythmia thiab lub cev pib tshee tshee los ntawm tsis muaj kev pw tsaug zog, (tshwj xeeb tshaj yog hmo ntuj nqus cov mis nyuj), Kuv hais kom kuv niam muab kuv txhaj tshuaj Cocarboxylase hydrochloride intramuscularly.
Zoo hmoo, kuv niam muaj kws kho mob thiab txhaj tshuaj, koj tsis tas yuav mus tom tsev kho mob.
Kuv txoj kev kho mob tau yooj yim: ib hnub kuv tau txhaj tshuaj nrog ATP (tseem rau kev txhawb nqa lub plawv).
Hnub ob, Cocarboxylase hydrochloride tau txhaj.
Hloov cov tshuaj no, kuv lub siab tau txais ib hom “vitamins” uas ua rau kuv muaj lub zog saib xyuas cov menyuam nyob ib puag ncig.
Cov pob ntawv muaj 10 fwj ntawm cocarboxylase + 10 lub raj mis ntawm cov kuab tshuaj rau cov thawj coj intramuscular.
Hmoov tsis zoo, Kuv tsis tuaj yeem pom ATF daim duab, vim tias cov kev txhaj tshuaj no dhau lawm. Thiab kuv niam yuav lwm pob khoom ntawm cocarboxylase. Ib feem ntawm cov lus qhia rau kev siv, Kuv yuav ua kom pom hauv daim duab. Tab sis nws meej meej hais tias nrog mob plawv tsis zoo thiab cov zaub mov tsis zoo rau lub cev, koj tuaj yeem hno cov tshuaj no. Kuv twb tau tachycardia lub sijhawm ntawd, txij li thaum kuv tsis tsaug zog ib txwm rau yuav luag ib nrab xyoo. Yog lawm, thiab kuv tus txiv ho tsis pab. Cov txheej txheem ntawm kev siv cov tshuaj no, Kuv tso tawm ua ntu zus mus. Leej twg hlub, koj tuaj yeem nyeem cov cog kev txhaj tshuaj ua ntej siv.
Kuv txoj kev kho mob, kom lub plawv rov qab thiab txhim kho qhov ua tau zoo, yog 20 hnub.
10 hnub ATP npaj + 10 hnub cocarboxylase npaj.
Cov kev txhaj tshuaj yog mob heev, tshwj xeeb yog cocarboxylase. Nws zoo li muv tau tom. Qhov kawg ntawm kev kho mob, Kuv twb quaj los ntawm kev txhaj tshuaj.
Tab sis tom qab ntawd yuav ua li cas kuv lub siab pib ua haujlwm. Tshiab li cas! Arrhythmia, tachycardia tau ploj mus, Kuv xav tias muaj kev nce siab ntawm lub zog thiab lub zog. Kuv tsis tu siab tias txhua qhov no dhau los. Txawm lub voj voog nyob hauv qab lub qhov muag ploj mus))).
Tus nqi ntawm cov tshuaj rau 10 ampoules yog 70 hryvnias, lossis 300 rubles.
Tag nrho cov chav kawm ntawm kev kho mob, nws raug nqi kuv 150 hryvnias (nrog rau ATP).
Kev txhaj tshuaj Cocarboxylase
Ntau lub tuam txhab tshuaj ua lag luam xa tawm Cocarboxylase, uas yog pawg B yooj yim vitamin .Txhua ampoule tuav 0.05 grams ntawm cov khoom tseem ceeb. Tsis tas li ntawd nyob rau hauv pob muaj ib qho ntxiv ampoule nrog kev daws rau diluting hmoov. Cov tshuaj muaj nyob rau hauv cov hmoov rau kev txhaj tshuaj, uas yuav yaj ua ntej tswj hwm ncaj qha. Cov pob muaj 5 lossis 10 ampoules.
Cov chaw muag tshuaj
Cov cuab yeej no muaj cov kev cuam tshuam hauv qab no rau ntawm lub cev:
- coenzyme
- nrog rau sodium thiab cov protein, nws ua kom nrawm carboxylation thiab decarboxylation,
- nrawm nrawm rau qhov tsim ntawm acetyl coenzyme A, uas ua rau kom muaj qhov tsis tu ncua ntawm cov metabolism hauv cov pluas (metabolism).
Cov Tshuaj Hauv Tshuaj
Nrog rau cov kev tswj hwm hauv tsoomfwv, cov tshuaj tiv thaiv yog nrawm thiab ua kom tiav rau feem ntau ntawm txoj hnyuv thiab duodenum. Tsuas yog 11 teev tom qab siv, cocarboxylase yog tshem tawm ntawm lub cev. Thaum lub sijhawm kawm txog cov tshuaj, tuaj yeem nrhiav pom tias nws muaj nyob hauv txhua daim ntaub so ntswg, thiab tshwj xeeb ntau hauv nws lub siab, lub siab thiab lub hlwb.
Cocarboxylase pab cov piam thaj kom nqus tau thiab ua haujlwm zoo rau CCC plab hnyuv siab raum. Tsis tas li, cov khoom tseem ceeb pab txhim kho cov ntaub so ntswg kev noj haus. Nws qhov tsis txaus ntseeg provokes tsub zuj zuj ntawm cov acids, thaum acidosis tsim thiab nws lub txim yog acidotic coma. Feem ntau cov feem ntau, Cocarboxylase raug pom zoo nyob rau hauv lub xub ntiag ntawm pathologies thaum lub sij hawm ua ntu zus uas muaj qhov tsis txaus endogenous.
Cov Tshuaj Pharmacokinetics
Thaum nws nkag mus rau hauv cov ntshav, qhov tseem ceeb ntawm cov tshuaj raug khaws los ntawm cov ntshav liab thiab kis mus thoob lub cev hauv daim ntawv ntawm thiamine diphosphate. Kev zom cov zaub mov tshwm sim hauv daim siab, thiab cov tshuaj tau tawm hauv qhov siv lub raum nrog zis.
Cov kws kho mob sau ntawv rau Cocarboxylase thaum tseem muaj kab mob hauv qab no:
- acidosis ntawm ntshav qab zib, cov ntaub ntawv ntawm metabolic thiab ua pa,
- lub plawv tsis ua hauj lwm
- raum tsis ua hauj lwm zoo,
- teeb meem ua pa
- cardiosclerosis uas tau tshwm sim tom qab lub plawv nres,
- metabolic mob ntawm carbohydrates,
- plawv nres
- lub siab tsis ruaj ntseg,
- mob plawv plawv, uas tshwm sim hauv ib daim ntawv uas mob ntev,
- coma mob ntshav qab zib thiab mob hepatic,
- haus cawv lom thiab nws lub txim,
- muaj cov keeb kwm ntawm cov neeg quav dej quav cawv,
- ntau yam sclerosis
- ntau yam kabmob sib kis
- sepsis tom qab los ntawm hypoxia thiab acidosis.
Cov Yuav Tsum Tau Ua
Tsuas yog ua kom tsis haum rau kev siv tshuaj yog qhov muaj kev tsis haum ntawm nws lub ntsiab lossis cov koom haum pabcuam.
Cov leeg ntshav tsis meej
Cov koob tshuaj cocarboxylase hauv cov kab mob no: 1 ampoule txog 3 zaug hauv ib hnub. Lub sijhawm tiv thaiv yuav yog los ntawm 14 hnub txog 1 hlis.
Cov neeg mob uas muaj tus kab mob no yuav tsum tau siv tshuaj hauv 100-1000 milligrams ib hnub twg txog 10 hnub yam tsis muaj hnub so. Ua ke nrog rau qhov no, nws yog ib qho tsim nyog yuav tsum tau noj lwm yam tshuaj rau ntshav qab zib.
Nyob rau hauv muaj mob raum thiab mob pob txha tsis txaus nyob rau hauv thawj ob peb hnub, cocarboxylase yog txhaj rau hauv txoj hlab ntshav 1-3 ampoules 3 zaug hauv ib hnub. Koj tseem tuaj yeem siv cov tshuaj drip. Txhawm rau ua qhov no, yaj cov tshuaj uas yuav tsum tau muaj nyob hauv 400 ml ntawm 5% piam thaj cov tshuaj.
Hauv cov kab mob no, cov tshuaj tau txais tshuaj intramuscularly rau 1-2 ampoules ib hnub. Lub chav kawm ntawm kev kho mob yog los ntawm 30 txog 45 hnub.
Cov menyuam yaus uas tsis tau ncav cuag 3 lub hlis muaj hnub nyoog tuaj yeem muab 25 mg ntawm cocarboxylase subcutaneously lossis intramuscularly. Cov neeg mob los ntawm 3 hlis txog 7 xyoo uas muaj hnub nyoog tau txhaj tshuaj mg ib hnub, thiab txij li 8 txog 18 xyoo, koj tuaj yeem siv mg.
Cev xeeb tub
Yog tias tus kws kho mob ua lub luag haujlwm thiab txiav txim siab sau ntawv rau Cocarboxylase rau tus poj niam cev xeeb tub, ces nws tau sib nrauj los ntawm cov piam thaj thiab vitamin C thiab muab tshuaj rau hauv lub cev. Lub sijhawm kho yog los ntawm 10 hnub txog ob hlis. Cov cim tseem ceeb rau kev siv cov tshuaj hauv lub sijhawm no yog:
Noj ntau dhau
Yog tias koj tshaj qhov koob tshuaj uas kws kho mob sau tseg, cov tsos mob hauv qab no yuav tshwm sim:
- lub plawv dhia
- mob
- ntxhoo
- kuv lub taub hau mob
- qaug zog thiab ua haujlwm dhau yog xav,
- cov leeg ntswj
- kev ua haujlwm ntawm cov hlab plawv yog cuam tshuam,
- hws intensifies,
- txog siav siav thiab ua xua tshwm sim.
Nrog rau kev txhim kho ntawm ib lossis ntau cov tsos mob, nws yog ib qho tsim nyog yuav tsum tso tseg txoj cai tswj hwm kev siv tshuaj thiab hu rau lub tuam tsev kho mob uas cov kws kho mob tuaj yeem muab kev pabcuam ua thawj zaug thiab ua cov tsos mob kev noj tshuaj.
Cov nyhuv Pharmacological
Coenzyme tsim nyob rau hauv lub cev los ntawm thiamine. Nws muaj cov txiaj ntsig metabolic, ua kom cov nqaij metabolism.
Hauv lub cev, nws yog phosphorylated los ua mono-, di- thiab triphosphoric esters, cocarboxylase yog ib feem ntawm cov enzymes uas catalyze carboxylation thiab decarboxylation ntawm keto acids, pyruvic acid, txhawb kev tsim ntawm acetyl coenzyme A, uas txiav txim siab nws koom nrog hauv metabolism metabolism. Kev koom tes hauv lub voj voog pentose yog ncaj qha txhawb nqa kev coj ua ntawm nucleic acids, proteins thiab lipids. Txhim kho cov kua nplaum txhaws, trophic cov hlab ntaws, pab ua kom lub luag haujlwm ntawm cov hlab plawv.
Cocarboxylase deficiency ua rau muaj kev nce qib ntawm pyruvic thiab lactic acids hauv cov ntshav, uas ua rau cov kab mob acidosis thiab acidic coma.
Kev ntsuas rau siv
Dab tsi pab? Cocarboxylase yog siv ua ke nrog lwm cov tshuaj hauv kev kho mob ntawm cov kab mob hauv qab no:
- Mob plawv tsis ua hauj lwm, post-infarction cardiosclerosis, mob hlab plawv, myocardial infarction, tsis khov lub siab,
- Acidosis nrog hyperglycemic coma, metabolic acidosis, acidosis nrog mob ntsws thiab ua pa tsis ua haujlwm,
- Mob raum thiab / lossis daim siab tsis ua haujlwm, mob ntev thiab mob cawv, lom, intoxication nrog barbiturates thiab mob glycosides, kis kab mob sib kis (kub taub hau, diphtheria, paratyphoid kub taub hau, mob npaws), ntau yam sclerosis, neuralgia, peripheral neuritis.
Tsis tas li, cov tshuaj tau tawm rau cov menyuam yaus lub sijhawm tsis muaj ntshav nrog hypoxia, ua pa tsis ua haujlwm, perinatal hypoxic encephalopathy, sepsis, mob ntsws, acidosis.
Cev xeeb tub thiab lactation
Cocarboxylase thaum cev xeeb tub raug tso cai ua haujlwm yog tias qhov kev cia siab muaj txiaj ntsig rau tus pojniam tseem ceeb tshaj qhov txaus ntshai rau tus menyuam. Yog tias koj xav siv cov tshuaj thaum lactation, koj yuav tsum sab laj nrog tus kws tshaj lij thiab txiav txim siab txog kev cuam tshuam ntawm kev pub niam mis.
Cocarboxylase thaum cev xeeb tub, yog tias muaj cov kab pathologies hauv kev loj hlob ntawm tus me nyuam hauv plab, yog txwv tsis pub siv.
Tsuas tshuaj thiab tswj hwm
Qhov kev txhaj tshuaj tov npaj los ntawm cov hmoov yog muab tshuaj intramuscularly lossis subcutaneously. Cov koob tshuaj ntawm cov tshuaj no tau tsim kho ib tus zuj zus, nyob ntawm qhov mob hnyav ntawm tus neeg mob thiab qhov xwm ntawm tus kab mob.
Cov neeg laus tau txhaj tshuaj 0.05-0.1 g ib hnub ib zaug, yog tias tsim nyog (mob ntshav qab zib tsis nco qab lawm), kev txhaj tshuaj dua tom qab 1-2 teev. Thaum muaj mob ntawm cov ntshav ncig tsis ua haujlwm, 0.05 g muab tshuaj 2 teev ua ntej noj digitalis npaj 2-3 zaug ib hnub.
Cov koob tshuaj txhua hnub ntawm Cocarboxylase rau cov menyuam hnub nyoog qis dua 3 hli yog 0.025 g, txij li 4 hlis txog 7 xyoo - 0.025-0.05 g, hnub nyoog 8-18 xyoo - 0.05-0.1 g.
Cov tshuaj tov tiav npaj los ntawm lyophilisate yog muab tshuaj intramuscularly lossis intravenously. Cov koob tshuaj ntawm cov tshuaj yog 0.05-0.2 g ib hnub. Qhov koob tshuaj txhua hnub rau cov neeg mob ntshav qab zib tuaj yeem nce mus txog 0.1-1 g .Txoj zaus thiab lub sijhawm kho yog txiav txim siab raws li kev ntsuas.
Rau cov menyuam yaus, txoj kev daws teeb meem yog siv cov tshuaj intramuscularly, ntxig rau (hauv cov kwj dej los yog kua dej), rau cov menyuam yug tshiab - sublingually. Cov koob tshuaj txhua hnub ntawm Cocarboxylase rau cov menyuam muaj hnub nyoog qis dua 3 hli yog 0.025 g, txij li 4 hlis txog 7 xyoo - 0.025-0.05 g, hnub nyoog 8-18 xyoo - 0.05-0.1 g Lub sijhawm kho yuav txawv ntawm 3-15 hnub.
Cov lus thiab cov xwm txheej ntawm kev cia
Muab cia rau hauv qhov chaw tsaus, qhuav thiab tsis ncav cuag ntawm cov menyuam. Hmoov - ntawm qhov kub thiab txias tsis tshaj 25 ° C, lyophilisate rau kev npaj cov tshuaj rau cov tshuaj thiab tshuaj intramuscular - 20 ° C, lyophilisate rau npaj cov tshuaj rau cov tshuaj intramuscular - 10 ° C.
Txee lub neej yog 3 xyoos.
Pom qhov yuam kev hauv cov ntawv nyeem? Xaiv nws thiab nias Ctrl + Enter.
Pharmacological kev txiav txim
Cocarboxylase muaj cov nyhuv coenzyme, zoo li nws coenzyme thiamineCov. Ua ke nrog cov protein thiab magnesium ions, nws catalyzes carboxylation thiab decarboxylation ntawm alpha keto acidsthiab nws kuj txhawb txoj kev kawmacetyl coenzyme A,yam li normalizing carbohydrate metabolism.
Yeeb tshuaj sib cuam tshuam
Cocarboxylase nquag ua ke nrog ntau yam tshuaj thiab cov tshuaj lom neeg lom. Xav txog cov kev sib cuam tshuam tseem ceeb:
- Nrog tshuaj tiv thaiv kab mob siab - muaj ib qho kev ua kom ntau ntxiv.
- Cov vitamins B ua rau kom muaj kev ua kom zoo ntawm kev kho kom zoo.
- Digoxin - provokes qhov txo qis hauv kev muaj peev xwm ntawm myocardiocyte kom nqus tau cov tshuaj nquag thiab nws cov tshuaj tiv thaiv.
Nws yog txwv tsis pub coj los ua ke nrog Cocarboxylase nrog cov tshuaj uas muaj kev sib cais lossis tsis zoo.
Kev cuam tshuam nrog lwm yam tshuaj
Raws li kev txheeb xyuas, Cocarboxylase, thaum ua ke, txhim kho kev kho mob ntawm cov mob glycosides.
Raws li cov lus qhia, kev sib xyaw cov tshuaj hauv ib qho koob txhaj nrog lwm cov tshuaj yog txwv tsis pub. Nws yog kev tso cai kom siv tsuas yog cov kuab tshuaj, uas nyob hauv lub thawv nrog tshuaj.
Cov lus thiab cov xwm txheej ntawm kev cia
Lub txee lub neej ntawm cov tshuaj yog 3 xyoos. Tom qab daws tau npaj tiav, nws yuav tsum siv tam sim ntawd.Raws li kev txheeb xyuas, Cocarboxylase yuav tsum muab tso kom deb ntawm cov menyuam yaus, hauv qhov chaw qhuav thiab tsaus.
Khaws cov tshuaj ntawm qhov kub tsis tshaj li 25 degrees Celsius.
Ib lub raj mis hmoov muaj: cocarboxylase hydrochloride - 50 milligrams thiab excipients.
Ib qho ampoule nrog cov kuab tshuaj muaj: dej rau kev txhaj tshuaj - 2 milligrams.
Cov lus qhia rau siv Cocarboxylase
Hauv Latin, lub npe ntawm cov tshuaj suab nrov zoo li Cocarboxylase, cov tshuaj yog tsim los ntawm cov tuam txhab hauv tsev thiab txawv teb chaws, nws tau paub ntev. Cocarboxylase hydrochloride ua cov tshuaj tiv thaiv, uas muaj cov yam ntxwv coenzyme, tshem tawm qhov pom ntawm acidosis thiab rov ua rau tib neeg lub cev ua haujlwm li qub.
Kev Sib Sau thiab daim ntawv ntawm kev tso tawm
Cov tshuaj tsuas yog paub hauv cov qauv ntawm lyophilisate - hmoov rau kev npaj cov tshuaj daws teebmeem. Muaj pes tsawg leeg thiab nqe lus piav qhia:
Homogeneous finely ntxeem tau hygroscopic loj ntawm cov xim dawb
Ib qho ampoule muaj 50 mg ntawm cocarboxylase hydrochloride thiab 2 ml ntawm cov kuab tshuaj - sodium acetate
Ampoules nrog hmoov ntawm 50 mg, hauv ib pob ntawm 5 ampoules
Kev cuam tshuam nrog lwm yam tshuaj
Cocarboxylase ua haujlwm zoo nrog ib tug xov tooj ntawm cov tshuaj thiab cov tshuaj lom biologically:
- tshuaj tiv thaiv kab mob nyob rau hauv ua ke nrog cov tshuaj - nce kev txiav txim siab,
- B vitamins - thaum noj cov tshuaj no, cov txiaj ntsig ntawm cov vitamins muaj zog dua,
- digoxin - lub peev xwm ntawm myocardiocytes los nqus cov khoom nquag ntawm cov tshuaj thiab nws cov metabolites txo qis,
- Kev siv cov tshuaj no ua ke nrog cov kev daws teeb meem nrog kev alkaline lossis nruab nrab tsis zoo yog tsis pom zoo.
Cocarboxylase Analogs
- Cocarboxylase Kev Cog Lus - yog coenzyme uas tau tsim nyob rau hauv lub cev los ntawm thiamine,
- Cocarboxylase Ferein - ib qho ua tiav ntawm cov tshuaj tau piav, uas muaj cov nyhuv zoo ib yam ntawm lub cev,
- Ellar Cocarboxylase,
- Cocarboxylase Hydrochloride - coenzyme ntawm enzymes koom nrog hauv cov metabolism hauv carbohydrates.
Kev txheeb xyuas ntawm Cocarboxylase
Kev txheeb xyuas ntawm cocarboxylase tuaj yeem nrhiav tau nyob hauv Is Taws Nem. Cov kws kho mob tawm ntawm kev tshuaj xyuas los ntawm qhov pom ntawm kev tshuaj ntsuam cov kws tshaj lij thiab cov neeg mob uas tau ntsib cov nyhuv ntawm cov tshuaj no rau lawv tus kheej.
Piv txwv li, ib tus kws kho mob Nikolai tau sau txog ib qho ntawm cov peev txheej:
«I / O cocarboxylase tuaj yeem muaj cov txiaj ntsig zoo rau cov neeg mob plawv tsis ua haujlwm. Nrog rau kev ua raws tag nrho nrog kuv cov lus pom zoo, 99% ntawm cov neeg mob thov tias cov tsos mob ntawm cov kab mob tsis zoo ploj mus tom qab 2-3 koob, uas twb tau hais txog cov txiaj ntsig ntawm cov tshuaj».
Tab sis Natalia, rau cov tshuaj uas tau sau tseg thaum lub sijhawm ntawm cev xeeb tub Nws sau hais tias nws tsis xav tias muaj kev hloov pauv pom, tab sis kev tshuaj ntsuam tom qab noj cov tshuaj pom tias muaj kev txhim kho zoo hauv nws txoj kev noj qab haus huv. Tom qab yug me nyuam, ib qho tshuaj noj ntawm cov tshuaj nyob rau hauv daim ntawv ntawm cov txwv tsis pub noj tshuaj tau muab rau siv los ntawm nws tus menyuam.
Nws yog xyaum tsis yooj yim sua kom pom cov kev txheeb xyuas nruab nrab lossis tsis zoo los ntawm cov neeg mob hauv Is Taws Nem, kuj tuaj yeem raug ntaus nqi rau qhov pom tseeb ntawm cov tshuaj no.
Tus nqi Cocarboxylase
Tus nqi ntawm cocarboxylase nyob ntawm daim ntawv tso tawm thiab chaw tsim tshuaj paus cog kev lag luam tshuaj nyob rau hauv daim ntawv tso cai tau los ntawm cov kws tsim kev lag luam. Daim ntawv teev cov nqi rau Cocarboxylase:
- hauv ampoules ntawm 50 mg N1 nrog MHFP solvent tsim los ntawm Moskhimpharmpreparat OJSC - nqi 47.00 rubles,
- hauv ampoules ntawm 50 mg N1 nrog cov kuab tshuaj tsim los ntawm Microgen NPO FSUE Tomsk, Virion - nqi 26,30 rubles,
- hauv ampoules ntawm 50 mg N1 nrog cov kuab tshuaj uas ua los ntawm MHFP - nqi 50.30 rubles,
- hauv ampoules ntawm 50 mg N1 nrog cov kuab tshuaj ua los ntawm Bryntsalov A - nqi 15.60 rubles,
- hauv ampoules ntawm 50 mg N1 nrog cov kuab tshuaj tsim los ntawm Moskhimpharmpreparaty (Russia) - nqi 7.30 rubles,
- hauv ampoules ntawm 50 mg N1 nrog cov kuab tshuaj tsim los ntawm Microgen NPO FSUE Perm, Biomed - nqi 180.00 rubles.
Thaum cev xeeb tub
Txog kev raug cai, kev tshawb fawb soj ntsuam ntawm cov txiaj ntsig ntawm cocarboxylase rau kev xeeb tub, lactating poj niam thiab lawv cov menyuam tsis tau ua. Vim li no, nws tsis pom zoo kom siv cov tshuaj no rau lub sijhawm no.
Yuav ua li cas Cocarboxylase cuam tshuam cov tshuaj tiv thaiv tus nqi thaum tsav tsheb lossis ua haujlwm nrog lwm cov txheej txheem tsis paub, vim tias cov tuam ntxhab tsis kawm txog cov teebmeem no.
Nrhiav tau
Koj tuaj yeem yuav yuav Cocarboxylase hauv kev txhaj tshuaj los ntawm kev muab tshuaj los ntawm koj tus kws kho mob, uas yuav qhia qhov yuav tsum tau txhaj thiab chav kawm ntawm kev kho mob.
Txhawm rau kom muaj kev kho mob kom zoo, nws yog ib qho tsim nyog kom ua raws li cov cai no:
- qhov ntsuas kub nyob hauv chav uas tso tshuaj yuav tsum tsis pub tshaj 25 degrees,
- vaum yuav tsum cia qis
- ampoules yuav tsum nyob deb ntawm menyuam yaus thiab ncaj qha tshav ntuj.
Lub sijhawm hnub tas sijhawm tau qhia ntawm pob thiab yuav tsum tsis pub dhau 36 lub hlis. Tom qab lub sijhawm no, ampoules yuav tsum tau muab pov tseg.
Cov lus qhia rau kev siv cov kev txhaj tshuaj ntawm Cocarboxylase qhia tias muaj cov tshuaj analogues no:
Tus nqi ntawm cov tshuaj yog nyob ntawm qhov chaw tsim tshuaj paus ntawm lub khw muag khoom thiab lub khw muag khoom muag. Tus nqi nruab nrab rau 5 ampoules ntawm Cocarboxylase yog nyob rau theem ntawm 50 rubles, uas ua rau cov tshuaj pheej yig rau ntau ntu ntawm cov neeg.
Cov lus qhia tshwj xeeb
Raws li ib feem ntawm Cocarboxylase, glycocholic acid tau thov, uas, nrog rov ua dua lossis ntev dua kev tswj hwm rau cov neeg mob jaundice lossis cholestasis, tuaj yeem ua rau daim siab ua haujlwm. Lwm cov lus qhia tshwj xeeb rau cov tshuaj:
- Tom qab diluting lub lyophilisate, txoj kev daws teeb meem tuaj yeem khaws cia tsis pub ntev tshaj li ib hnub ntawm qhov kub ntawm 2-8 degrees, thiab nws zoo dua siv nws tam sim ntawd.
- Nws tsis paub meej tias cov tshuaj muaj feem cuam tshuam rau kev ceev thiab kev mloog zoo li cas, vim hais tias cov neeg mob tau txais kev kho mob tau mob nyhav thiab mob hnyav thiab lub cev tsis tuaj yeem tsav cov tsheb thiab cov tshuab.
Cocarboxylase thaum cev xeeb tub
Kev qhia rau kev siv tshuaj thaum lub cev xeeb tub yog hypoxia tus me nyuam thiab kev kho mob ntawm toxicosis ua ib feem ntawm txoj kev kho mob. Cov poj niam cev xeeb tub tau sau tseg ib chav kawm ntawm kev siv tshuaj rau 10 hnub ntawm 50 mg / hnub. Lub lyophilisate yog yaj hauv 20 ml ntawm cov piam thaj, kev txhaj tshuaj tau muab tso rau hauv qhov nyuaj nrog txoj kev daws ntawm ascorbic acid (vitamin C).
Cov nqe lus ntawm kev muag khoom thiab cia
Koj tuaj yeem yuav cov tshuaj tsuas yog los ntawm cov tshuaj noj. Cov tshuaj no tau khaws cia ntawm qhov kub txog 25 degrees hauv qhov chaw tsaus tsaus uas tsis muaj chaw nkag tau rau tshav ntuj tau peb xyoos txij li kev tsim khoom.
Muaj ob peb lub npe nrov tshuaj hloov chaw ntawm cov tuam txhab sib txawv, tab sis muaj tib lub npe. Lawv piav qhia:
- Cocarboxylase Improv - coenzyme tau hauv lub cev los ntawm thiamine,
- Cocarboxylase Ferin yog ib qho ua tiav ntawm kev noj tshuaj nrog tib yam kev kho mob,
- Ellar cocarboxylase yog ib tus neeg sawv cev khoom noj zom khoom noj hauv daim ntawv ntawm lyophilisate,
- Cocarboxylase Hydrochloride yog coenzyme koom nrog hauv cov khoom noj metabolism.
Cocarboxylase - cov lus qhia rau kev siv, analogues, tshuaj xyuas thiab tso tawm cov ntawv (txhaj hauv ampoules rau cov leeg thiab intramuscular txhaj ntawm hydrochloride) ntawm cov tshuaj rau kev kho mob acidosis thiab coma rau cov laus, menyuam yaus thiab cev xeeb tub. Muaj pes tsawg leeg
Hauv tsab xov xwm no, koj tuaj yeem nyeem cov lus qhia txog kev siv tshuaj yeeb yeeb Cocarboxylase. Muab cov lus pom zoo los ntawm cov neeg tuaj saib rau ntawm thaj chaw - cov neeg siv khoom ntawm cov tshuaj no, nrog rau kev xav ntawm cov kws kho mob tshwj xeeb txog kev siv Cocarboxylase hauv lawv cov kev coj ua. Kev thov loj yog nquag ntxiv kev tshuaj xyuas koj ntawm cov tshuaj: cov tshuaj tau pab lossis tsis pab ua kom tshem tawm ntawm tus kabmob, muaj dab tsi tshwm sim thiab cov kev mob tshwm sim, tejzaum nws tsis tshaj tawm los ntawm tus tsim khoom hauv cov lus piav qhia. Cov tshuaj tiv thaiv ntawm Cocarboxylase nyob rau hauv muaj cov qauv txheej txheem. Siv rau kev kho mob ntawm acidosis, mob ntshav qab zib tsis xeev thiab daim siab thiab lub raum tsis ua hauj lwm hauv cov neeg laus, menyuam yaus, nrog rau lub sijhawm cev xeeb tub thiab lactation. Cov tshuaj muaj pes tsawg leeg.
Cocarboxylase yog coenzyme uas tau tsim hauv lub cev los ntawm thiamine. Nws muaj cov txiaj ntsig metabolic, ua kom cov nqaij metabolism. Hauv lub cev, nws yog phosphorylated los ua mono-, di- thiab triphosphoric esters, cocarboxylase yog ib feem ntawm cov enzymes uas catalyze carboxylation thiab decarboxylation ntawm keto acids, pyruvic acid, txhawb kev tsim ntawm acetyl coenzyme A, uas txiav txim siab nws koom nrog hauv metabolism metabolism. Kev koom tes hauv lub voj voog pentose yog ncaj qha txhawb nqa kev coj ua ntawm nucleic acids, proteins thiab lipids.
Txhim kho cov kua nplaum txhaws, trophic cov hlab ntaws, pab ua kom lub luag haujlwm ntawm cov hlab plawv.
Cocarboxylase deficiency ua rau muaj kev nce qib ntawm pyruvic thiab lactic acids hauv cov ntshav, uas ua rau cov kab mob acidosis thiab acidic coma.
Cocarboxylase hydrochloride + nrog rau kev xa tawm.
- metabolic acidosis
- hyperglycemic coma thiab acidosis mob ntshav qab zib mellitus,
- daim siab ua hauj lwm
- lub raum tsis ua hauj lwm
- ua pa acidosis rau mob ntsws, mob plawv tsis ua haujlwm,
- ua pa tsis ua hauj lwm
- mob ntshav siab tsis ua haujlwm,
- myocardial infarction thiab post-infarction cardiosclerosis (raws li ib feem ntawm cov kev kho mob nyuaj),
- qaug cawv lom,
- haus cawv ntev,
- kev lom zem digitalis, barbiturates,
- intoxication nyob rau hauv cov kis kab mob: kab mob diphtheria, scarlet kub taub hau, mob typhoid thiab paratyphoid (nyob rau hauv txoj kev kho mob),
- peripheral neuritis.
Hauv cov menyuam yaus thaum lub sijhawm yug menyuam:
- hlwv hypoxic encephalopathy,
- ua pa tsis ua hauj lwm
- mob ntsws
- sepsis
- hypoxia
- tshuaj mob ntsws.
Lyophilisate rau kev npaj ntawm kev daws rau cov tshuaj ua haujlwm ntawm intravenous thiab intramuscular (kev txhaj tshuaj hauv ampoules rau kev txhaj tshuaj).
Tsis muaj lwm daim ntawv sau tshuaj, yog nws ntsiav tshuaj lossis cov tshuaj tiv thaiv.
Cov lus qhia rau kev siv thiab txheej txheem ntawm kev siv
Cov neeg laus yog muab cov tshuaj intramuscularly lossis intravenously. Qhov koob tshuaj yog mg rau ib hnub. Hauv cov ntshav qab zib mellitus (acidosis, coma), qhov koob tshuaj txhua hnub tuaj yeem yog 0.1-1 g. Qhov nquag thiab lub sijhawm siv yog nyob ntawm cov ntsuas.
Rau cov menyuam yaus - hauv / m, hauv / hauv (dej ntws (dej ntws) lossis dav hlau), rau cov menyuam yug tshiab - sublingually. Cov menyuam yaus txog 3 hlis - 25 mg ib hnub twg, txij li 4 hlis txog 7 xyoo, ib hnub, los ntawm 8 txog 18 xyoo rau ib hnub. Lub sijhawm tiv thaiv yog los ntawm 3-7 mus rau 15 hnub.
- kev ua xua (urticaria, khaus),
- hyperemia, khaus thiab o ntawm thaj chaw txhaj tshuaj.
- hypersensitivity rau cocarboxylase.
Cev xeeb tub thiab lactation
Hais txog qhov ua tau zoo thiab kev nyab xeeb ntawm kev siv cocarboxylase thaum cev xeeb tub, kev tshawb fawb txog kev kho mob tseem tsis tau ua. Yog li ntawd, cov ntaub ntawv txhim khu kev qha ntawm contraindication ntawm cocarboxylase lub sijhawm no tsis yog. Tus kws kho mob qhov kev sab laj xav tau.
Kev thov yuav siv tau raws li cov tshuaj noj tau tshuaj.
Ua kom cov txiaj ntsig kev mob plawv cardiotonic thiab txhim kho lawv lub siab ntev.
Cov tshuaj ntawm cov tshuaj Cocarboxylase
Cov qauv ntawm cov qauv ua haujlwm:
- Cocarboxylase cog,
- Cocarboxylase Ferein,
- Ellar Cocarboxylase,
- Cocarboxylase hydrochloride.
Cov tshuaj hauv cov pawg tshuaj (cov neeg sawv cev rau kev kho mob acidosis):
- Alpha D3 Teva,
- Dimephosphone,
- Kalinor
- Quintasol,
- Sodium bicarbonate,
- Compound sodium lactate,
- Stylamine
- Trometamol N.
Cov khoom thiab kev nqis tes ua
Endogenously cocarboxylase yog tsim los ntawm cov vitamins B 1, thiab yog coenzyme. Coenzymes (coenzymes) yog cov chaw sawv cev ntawm cov enzymes - cov nqaijrog uas pabcuam rau catalysts rau txhua qhov kev hloov biochemical. Cov haujlwm ntawm coenzymes feem ntau yog ua los ntawm cov vitamins. Cocarboxylase yog coenzyme ntawm enzymes uas tswj saccharide metabolism. Ua ke nrog cov protein thiab magnesium ions, nws yog ib feem tseem ceeb ntawm carboxylase enzyme, uas ua haujlwm ua tus tswj kev noj zaub mov saccharide metabolism, tiv thaiv kom tsis txhob tsub zuj zuj ntawm cov kab mob lactic thiab pyruvic acids hauv lub cev, thiab txhawb kev nqus ntawm cov kua nplaum. Tag nrho cov no pab txhawb kom muaj kev ua tau zoo ntawm lub zog, uas txhais tau tias cov metabolism zoo dua thoob plaws lub cev.
Thiamine, nkag mus rau hauv lub cev, yog thawj zaug rau cocarboxylase, thiab tsuas yog nyob rau hauv daim ntawv no koom nrog cov txheej txheem hauv metabolic. Yog li, cocarboxylase yog ib qho kev ua kom nquag plias ntawm coenzyme uas tau txais los ntawm thiamine thaum nws qhov kev txiav tawm tsis ua hauj lwm. Txawm li cas los xij, cov khoom siv biochemical ntawm thiamine pyrophosphate tsis zoo ib yam li thiamine; yog li ntawd, cocarboxylase tsis yog siv rau hauv kev kho mob los ntawm cov kab mob vim tsis muaj vitamin B 1. Nws yog siv nyob rau hauv txoj kev kho rau ntau yam pathological uas yuav tsum muaj kev ruaj khov ntawm cov metabolism carbohydrate.
Thiamine pyrophosphate txhawb nqa kev nqus ntawm cov piam thaj, normalizes metabolism hauv cov hlab ntsha cov hlab ntsha, rov qab ua haujlwm ntawm lub siab nqaij. Tsis muaj cocarboxylase ua rau kev ua txhaum ntawm cov kua qaub-lub hauv paus ntawm kev sib luag ntawm cov ntshav (acidosis), uas ua rau muaj kab mob hnyav ntawm txhua yam kabmob thiab tshuab, thiab tuaj yeem ua rau lub cev tsis nco qab thiab tuag taus.
Cov txiaj ntsig ntawm cocarboxylase tau raug pov thawj los ntawm ntau qhov kev tshawb fawb soj ntsuam.