Lisinopril Teva: cov lus qhia rau kev siv, analogues, chaw tsim tshuaj paus, tshuaj xyuas

- arterial hypertension (hauv monotherapy lossis hauv kev sib xyaw nrog lwm cov tshuaj antihypertensive),

- mob plawv tsis ua hauj lwm (raws li ib feem ntawm txoj kev kho ua ke),

- kev kho mob thaum ntxov ntawm tus mob myocardial infarction (hauv thawj 24 teev nrog cov hemodynamics ruaj khov los tswj cov ntsuas no thiab tiv thaiv sab laug ventricular kawg thiab lub plawv tsis ua haujlwm),

- mob ntshav qab zib nephropathy (txo qis albuminuria hauv cov neeg mob uas muaj hom 1 mob ntshav qab zib mellitus nrog cov ntshav siab, thiab hauv cov neeg mob uas muaj ntshav qab zib hom 2 mob ntshav qab zib).

Cov Yuav Tsum Muaj

- Ua haujlwm siab rau lisinopril, lwm yam tshuaj ntawm tshuaj lossis lwm yam tshuaj tiv thaiv ACE,

- keeb kwm ntawm angioedema (suav nrog siv lwm tus ACE inhibitors),

- tshuaj tiv thaiv kab mob Quincke edema thiab / lossis idiopathic angioedema,

- lub hnub nyoog txog 18 xyoo (qhov ua tau zoo thiab kev nyab xeeb tsis tau tsim tsa),

- Cev xeeb tub thiab lub sijhawm pub mis niam.

Cov kev ceev faj: ob tog lub raum artery stenosis lossis stenosis ntawm tib lub raum artery nrog azotemia nce siab, mob tom qab lub raum hloov pauv, raum tsis ua haujlwm, hemodialysis siv high-flow dialysis membranes (AN69R), azotemia, hyperkalemia, stenosis ntawm aortic orifice, hypertrophic obstructive cardiomyroopathy mob ntshav siab, kab mob cerebrovascular (suav nrog cerebrovascular tsis txaus), mob plawv, mob tsis txaus rau lub plawv, mob tsis ua haujlwm cov ntaub so ntswg sib txuas (suav nrog scleroderma, cov kab mob lupus erythematosus), kev txwv tsis pub cov pob txha txha ntshav, cov mob nrog rau qhov txo qis hauv lub cev ntshav ntau ntau (BCC) (suav nrog rau mob raws plab, ntuav), siv rau hauv cov neeg mob noj cov zaub mov uas txwv cov lus ntsev, hauv cov neeg laus cov neeg mob, ib txhij siv nrog npaj poov tshuaj, diuretics, lwm yam tshuaj tiv thaiv kabmob, NSAIDs, lithium npaj, antacids, colestyramine, ethanol, insulin, lwm yam kev tiv thaiv hypoglycemic Tami, allopurinol, procainamide, kub npaj, antipsychotics, tricyclic antidepressants, barbiturates, beta-blockers, calcium channel blockers qeeb.

Yuav siv li cas: noj ntau thiab hom tshuaj kho

Cov tshuaj Lisinopril-Teva yog noj ntawm qhov ncauj 1 zaug / hnub, tsis hais lub sijhawm noj mov, zoo dua rau tib lub sijhawm ntawm ib hnub. Cov koob tshuaj yog xaiv tau ib tus zuj zus. Nrog rau cov hlab ntsha o, cov neeg mob tsis tau txais lwm cov tshuaj antihypertensive siv 5 mg / hnub. Thaum tsis siv tshuaj kho, qhov koob tshuaj tau nce ntxiv txhua 2-3 hnub los ntawm 5 mg rau qhov koob tshuaj 20-40 mg / hnub (nce ntau dua koob saum 40 mg / hnub feem ntau tsis ua rau txo qis ntshav siab).

Qhov nruab nrab cov tshuaj saib xyuas txhua hnub yog 20 mg. Qhov nyiaj pab ntau tshaj txhua hnub yog 40 mg. Cov txiaj ntsig kho feem ntau loj hlob tom qab 2-4 lub lis piam los ntawm kev pib kho, uas yuav tsum tau txiav txim siab thaum nce qhov koob. Nrog cov txiaj ntsig tsis txaus, tib lub sij hawm siv cov tshuaj nrog lwm cov tshuaj tiv thaiv kabmob muaj peev xwm ua tau.

Yog tias tus neeg mob tau txais kev kho mob ua ntej nrog diuretics, tom qab ntawd qhov kev noj tshuaj ntawm no yuav tsum nres 2-3 hnub ua ntej pib siv cov tshuaj Lisinopril-Teva. Yog tias qhov no ua tsis tau, ces thawj zaug kev noj tshuaj ntawm Lisinopril-Teva yuav tsum tsis pub tshaj 5 mg / hnub. Hauv qhov no, tom qab noj thawj koob, kev saib xyuas kev noj qab haus huv raug pom zoo rau ob peb teev (qhov siab tshaj plaws ua tiav tau tom qab kwv yees li 6 teev), txij li pom qhov txo qis hauv ntshav siab tuaj yeem tshwm sim.

Pharmacological kev txiav txim

ACE inhibitor, txo qhov tsim ntawm angiotensin II los ntawm angiotensin I. Txo cov ntsiab lus ntawm angiotensin II ua rau txo qis ncaj qha rau kev tso tawm aldosterone. Txo cov kev ua haujlwm ntawm bradykinin thiab nce cov synthesis ntawm prostaglandins. Txo tag nrho peripheral vascular tsis kam (OPSS), ntshav siab, preload, siab nyob rau hauv cov hlab ntsws capillaries, ua rau kev nce ntshav feeb thiab nce myocardial ce kam rau hauv cov neeg mob uas mob plawv tsis ua haujlwm. Nthuav cov hlab ntsha mus rau qhov ntau dua li cov leeg ntshav. Qee qhov teebmeem tshwm sim ua rau muaj qhov cuam tshuam nrog renin-angiotensin-aldosterone system (RAAS). Nrog rau siv ntev, hypertrophy ntawm myocardium thiab phab ntsa ntawm cov hlab ntsha ntawm hom tiv thaiv poob qis. Txhim kho cov ntshav xa mus rau ischemic myocardium.

Lisinopril txo albuminuria. Nws tsis cuam tshuam rau cov ntshav qabzib hauv cov neeg mob ntshav qab zib mellitus thiab tsis ua rau muaj kev nce ntxiv hauv cov neeg mob ntshav qab zib.

Sab sij huam

Los ntawm cov hlab plawv: feem ntau - lub cim txo qis rau cov ntshav siab, orthostatic hypotension, ua tsis xws luag - mob myocardial infarction, tachycardia, palpitations, Raynaud's syndrome, tsis tshua muaj - bradycardia, tachycardia, kev mob siab ntxiv ntawm cov tsos mob ntawm lub plawv tsis ua haujlwm, tsis hnov ​​qab ntawm lub plawv atrioventricular conduction, mob hauv siab.

Los ntawm lub hauv nruab nrab hauv cov hlab ntsha hauv lub cev: feem ntau - kiv taub hau, mob taub hau, ua tsis tau - mob lub siab, nqaij tawv, pw tsaug zog, mob stroke, tsis tshua muaj - tsis meej pem, asthenic syndrome, ua rau pob tw ntawm cov leeg ntawm nqaj thiab daim di ncauj, tsaug zog.

Nyob rau ib feem ntawm hematopoietic system thiab lymphatic system: tsis tshua muaj - ib qho kev txo qis ntawm hemoglobin, hematocrit, tsis tshua muaj - leukopenia, neutropenia, agranulocytosis, thrombocytenia, eosinophilia, erythropenia, hemolytic anemia, lymphadenopathy, autoimmune mob hlwb.

Cov lus qhia tshwj xeeb

Feem ntau, qhov cim tseg ntawm cov ntshav siab tshwm sim nrog qhov kev txo qis hauv BCC tshwm sim los ntawm kev kho mob diuretic, txo qis hauv cov ntsiab lus ntawm sodium chloride hauv zaub mov, lim ntshav, raws plab thiab ntuav. Nyob rau hauv kev saib xyuas ntawm kws kho mob, nws raug nquahu kom siv cov tshuaj Lisinopril-Teva nyob rau hauv cov neeg mob ua mob rau cov hlab ntshav txhaws, cerebrovascular tsis txaus, nyob rau hauv uas txo qis hauv cov ntshav siab tuaj yeem ua rau myocardial infarction lossis mob stroke. Kev siv cov tshuaj Lisinopril-Teva tuaj yeem ua rau lub raum ua rau lub raum tsis zoo, mob raum tsis ua haujlwm, uas feem ntau tsis tuaj yeem cuam tshuam txawm tias tom qab txiav tsis siv tshuaj. Transient arterial hypotension tsis yog qhov kev txwv rau kev siv tshuaj ntxiv.

Thaum muaj mob stenosis ntawm lub raum leeg mob (tshwj xeeb tshaj yog nrog ob tog stenosis lossis nyob rau ntawm lub cev ntawm lub raum ntawm tib lub raum), nrog rau qhov ua kom lub plawv tsis ua haujlwm, los ntawm kev mob hyponatremia thiab hypovolemia, kev siv cov tshuaj Lisinopril-Teva tuaj yeem ua rau lub raum tsis ua haujlwm, mob raum tsis ua haujlwm, uas feem ntau tsis tuaj yeem tom qab tshem tawm cov tshuaj.

Kev sib txuam

Nrog ceev faj, lisinopril yuav tsum siv ib txhij nrog potassium-sparing diuretics (spironolactone, triamteren, amiloride, eplerenone), cov poov tshuaj npaj, ntsev hloov pauv muaj cov poov tshuaj, cyclosporine - qhov kev pheej hmoo ntawm hyperkalemia yog nce, tshwj xeeb tshaj yog nrog kev ua haujlwm tsis zoo hauv lub raum. Yog li, cov kev sib xyaw no yuav tsum siv tsuas yog txiav txim siab ntawm tus kws kho mob qhov kev txiav txim siab nrog kev soj ntsuam cov poov tshuaj poov xab thiab lub raum kev ua haujlwm. Nrog tib lub sijhawm siv nrog diuretics thiab lwm cov tshuaj tiv thaiv kev tiv thaiv, qhov ua rau cov roj ntsha ntawm cov lisinopril kho kom zoo.

Nrog rau kev siv tib lub sijhawm nrog NSAIDs (suav nrog kev xaiv cyclooxygenase-2 (COX-2) inhibitors), acetylsalicylic acid ntawm ib koob ntawm ntau dua 3 g / hnub, estrogens, thiab tseem sympathomimetics, cov nyhuv antihypertensive ntawm lisinopril txo. NSAIDs, suav nrog COX-2, thiab ACE inhibitors tsub kom cov poov tshuaj poov tshuaj ntau ntau thiab tuaj yeem ua rau lub raum tsis ua haujlwm ntxiv. Cov nyhuv no feem ntau thim rov qab. Lisinopril qeeb qeeb qhov tsis pom kev ntawm cov roj ntsha lithium npaj, yog li ntawd, nrog kev siv tib lub sijhawm, kev thim rov qab nws qhov kev tso siab hauv cov ntshav plasma tshwm sim, uas tuaj yeem ua rau muaj kev pheej hmoo ntawm kev tsim cov xwm txheej tsis zoo, yog li ntawd, cov concentration ntawm lithium hauv cov dej yuav tsum tau soj ntsuam tas li.

Nrog rau kev siv ua ke nrog antacids thiab colestyramine, kev nqus ntawm lisinopril los ntawm kev mob plab hnyuv kom tsawg.

Cov lus nug, lus teb, tshuaj xyuas ntawm cov tshuaj Lisinopril-Teva

Cov ntaub ntawv muab yog npaj rau kev kho mob thiab kws tshaj lij. Cov ntaub ntawv muaj tseeb tshaj plaws txog cov tshuaj muaj nyob hauv cov lus qhia uas txuas nrog lub ntim los ntawm cov kws tsim khoom lag luam. Tsis muaj cov ntaub ntawv tso tawm rau ntawm no lossis lwm nplooj ntawv ntawm peb lub xaib tuaj yeem hloov chaw rau qhov tsis txaus siab tus kheej rau tus kws tshaj lij.

Thaum twg cov tshuaj nrog kev ceev faj?

Raws li txoj cai, ceev faj siv "Lisinopril Teva" yog muaj qhia hauv qab no:

• Kev mob raum tsis zoo nrog rau ob leeg lub raum ua rau cov leeg ntshav liab nrog rau azotemia muaj txiaj ntsig thiab tiv thaiv keeb kwm ntawm ib qho mob tom qab hloov chaw ntawm cov khoom no.
• Nrog hyperkalemia, stenosis ntawm lub qhov ncauj ntawm lub aorta, hypertrophic obstructive cardiomyopathy.
• Tawm tsam keeb kwm ntawm cov thawj hyperaldosteronism, arterial hypotension thiab kab mob cerebrovascular (suav nrog rau cov hlab ntsha tsis ua haujlwm hauv lub hlwb).
• Nyob rau ntawm qhov muaj mob ntawm cov mob ntshav plawv, mob ntshav siab tsis txaus, roj ntsha tiv thaiv kabmob ntawm cov kabmob ntawm cov nqaij sib txuas (suav nrog scleroderma, kab mob lupus erythematosus).
• Thaum inhibition ntawm cov hlwb pob txha hematopoiesis.
• Nrog zaub mov noj kom tsawg nyob rau hauv ntsev.
• Tawm tsam keeb kwm ntawm hypovolemic tej yam tshwm sim los ntawm kev zawv plab lossis ntuav.
• Hnub nyoog laus.

Cov lus qhia rau kev siv

Cov ntsiav tshuaj "Lisinopril Teva" yog siv qhov ncauj ib hnub ib zaug, thaum sawv ntxov, tsis hais noj zaub mov, nyiam dua tib lub sijhawm. Thaum muaj mob ntshav ncig ntawm cov ntshav siab, cov neeg mob uas tsis tau txais lwm cov tshuaj tiv thaiv kabmob tuaj yeem kho 5 milligrams ib hnub ib zaug. Yog tias tsis muaj tshwm sim, qhov ntau npaum li cas tau nce txhua txhua peb hnub los ntawm 5 milligrams mus rau qhov nruab nrab kho qhov nruab nrab ntawm 40 milligrams (nce ntxiv ntau dua qhov ntim no tsis feem ntau ua rau txo qis ntxiv hauv siab). Cov tshuaj uas ib txwm txhawb nqa ntawm cov tshuaj yog 20 milligrams.

Cov txiaj ntsig tag nrho, raws li txoj cai, tsim tawm tom qab plaub lub lis piam los ntawm kev pib kho, uas yuav tsum tau txiav txim siab thaum nce qhov ntim ntawm cov tshuaj. Tawm tsam keeb kwm ntawm cov kab mob tsis txaus ntseeg, kev sib txuam ntawm cov tshuaj no nrog lwm cov tshuaj tiv thaiv kabmob muaj peev xwm ua tau. Yog tias tus neeg mob tau noj cov tshuaj diuretics yav dhau los, tom qab ntawd lawv siv yog qhov tseem ceeb kom nres peb hnub ua ntej pib siv "Lisinopril Teva." Yog tias qhov no ua tsis tau, ces kev siv tshuaj thawj zaug yuav tsum tsis pub tshaj 5 milligrams ib hnub. Tom qab thawj koob tshuaj, nws raug nquahu kom ua tiav kev soj ntsuam kev kho mob rau ob peb teev (qhov siab tshaj plaws ua tiav tau tom qab kwv yees li ib nrab ntawm ib hnub), vim hais tias cov lus tshaj tawm hauv lub siab tuaj yeem pom.

Nyob rau ntawm qhov kev hloov kho lub plawv tawg lossis lwm yam kev mob nrog ntau dhau ntawm kev ua haujlwm ntawm renin-aldosterone system, nws kuj tseem xav tau sau ntawv rau kev noj tshuaj me me thawj zaug ntawm 5 milligrams raws li cov kws kho mob tau tswj hwm. Cov txij nkawm qhov ntau npaum li cas ntawm cov tshuaj yuav tsum txiav txim siab nyob ntawm qhov kev hloov pauv ntawm lub siab.

Tawm tsam cov keeb kwm ntawm kev kub siab dhau, kev kho mob mus sij hawm ntev yog qhia ntawm 15 milligrams ntawm cov tshuaj ib hnub. Hauv kev mob plawv tsis ua haujlwm, lawv thawj zaug haus dej 2.5 nrog maj mam nce ntxiv tom qab tsib hnub rau 5 lossis 10 milligrams. Qhov siab kawg txhua hnub koob yog 20 milligrams.

Hauv cov mob myocardial infarction (raws li ib feem ntawm kev sib xyaw ua ke), 5 milligrams qaug cawv rau thawj hnub, tom qab ntawd tus nqi qub tom qab nees nkaum plaub teev thiab 10 tom qab ob hnub. Tom qab ntawd noj 10 milligrams ib hnub ib zaug. Lub chav kawm ntawm kev kho mob yog tsawg kawg yog rau lub lis piam. Thaum lub sij hawm txo qis hauv lub siab, kev kho nrog cov tshuaj hauv cov lus nug yuav tsum tau tsum tsis ua ntxiv.

Tawm tsam keeb kwm ntawm nephropathy nyob rau hauv cov neeg mob uas muaj ntshav qab zib hom 2, 10 milligrams siv ib zaug ib hnub. Yog tias tsim nyog, koob tshuaj tuaj yeem raug nce ntxiv txog 20 txhawm rau kom ua tiav diastolic siab tus nqi hauv qab 75 millimeters ntawm cov mercury hauv qhov chaw zaum. Rau cov neeg mob uas muaj ntshav qab zib hom 1, cov tshuaj ntau npaum li cas yog tib yam.

Noj ntau dhau

Cov tsos mob ntawm kev haus ib ce yog cov lus txo qis hauv siab nrog rau qhov dryness ntawm lub qhov ncauj qhov ncauj, qhov dej tsis haum electrolyte, ua pa thiab tachycardia. Qhov no tau lees paub los ntawm cov lus qhia rau kev siv thiab tshuaj xyuas. "Lisinopril Teva" tuaj yeem ua rau lub siab xav ua ke nrog kev sib zog ua ke nrog duav, kiv taub hau, ntxhov siab, nce ntxiv kev npau taws, tsaug zog, tso zis tawm tsam, cem quav, vau, mob ntsws ntsws.

Txoj kev kho yuav tsum yog kev kho mob lub nra hnyav, siv cov tshuaj enterosorbents thiab laxatives. Qhov dej tshuaj sodium chloride yog qhia. Nws kuj yuav tsum tau tswj ntawm siab thiab electrolyte sib npaug. Hemodialysis yuav siv tau.

Tus nqi ntawm cov tshuaj no hauv qhov ntau npaum ntawm 10 mg yog tam sim no txog 116 rubles. Nws nyob ntawm thaj av thiab lub tsev muag tshuaj network.

Cov lus qhia ntawm "Lisinopril Teva"

Kev hloov cov tshuaj hauv cov lus nug yog Diroton, Irumed, thiab Lysinoton. Nws yog ib qho tseem ceeb kom to taub tias tsuas yog kws kho mob yuav tsum sau ntawv rau noj lwm yam tshuaj xwb tsis yog qhov uas tau piav qhia los ntawm peb.

Hauv lawv cov lus, tib neeg hais tias "Lisinopril Teva" yog ib qho tshuaj zoo rau kev tawg. Nws tau sau tseg tias nws tsim nyog rau kev kho mob monotherapy, nrog rau kev sib xyaw nrog lwm cov tshuaj tiv thaiv kabmob.

Ntxiv nrog rau kev sib xyaw nrog cov ntshav siab, cov tshuaj pab cov neeg mob plawv tsis ua haujlwm ntev, thiab ua ib feem ntawm kev kho thaum ntxov ntawm kev mob plawv nres.

Hauv kev tshuaj xyuas ntawm "Lisinopril Teva" muaj kev tsis txaus siab ntawm cov kev mob tshwm sim hauv daim ntawv ntawm kev tawm hws ntau ntxiv thiab qhov tshwm sim ua pob rau ntawm daim tawv nqaij. Tab sis txwv tsis pub, cov tshuaj no yog cov neeg nyiam siv nws rau nws cov hauj lwm zoo thiab tsim nyog tus nqi.

Dosage daim ntawv

5 mg, 10 mg, 20 mg ntsiav tshuaj

Ib ntsiav tshuaj muaj

cov tshuaj yeeb dej caw yog lisinopril dihydrate 5.44 mg, 10.89 mg lossis 21.78 mg, sib npaug lisinopril anhydrous 5 mg, 10 mg, 20 mg,

kev zam: mannitol, calcium hydrogen phosphate dihydrate, pregelatinized hmoov txhuv nplej siab, zas PB-24823, croscarmellose sodium, magnesium stearate.

Cov ntsiav tshuaj yog xim dawb, puag ncig, biconvex, nrog ib qho kev ceeb toom rau ntawm ib sab (rau qhov ntau npaum li 5 mg).

Cov ntsiav tshuaj yog lub teeb xim liab xim, puag ncig, biconvex, nrog kev pheej hmoo ntawm ib sab (rau qhov ntau npaum li 10 mg).

Cov ntsiav tshuaj yog xim paj yeeb, puag ncig, biconvex nrog ib qho kev ceeb toom rau ntawm ib sab (rau qhov ntau npaum li 20 mg).

Cov chaw muag tshuaj

Qhov siab tshaj plaws hauv cov ntshav ntshav tau mus txog kwv yees li 7 teev tom qab kev tswj hwm ntawm qhov ncauj. Noj mov tsis cuam tshuam rau tus nqi ntawm kev nqus ntawm lisinopril. Lisinopril tsis khi rau cov nqaijrog plasma. Qhov kev nqus xyoob ntoo xyoob ntoo nyob nrog kom puv thiab hloov pauv tsis tau dhau ntawm lub raum. Kev pib ib nrab-lub neej yog 12.6 teev. Lisinopril hla lub tsho me me.

Lisinopril-Teva yog ib qho inhibitor ntawm angiotensin-hloov pauv enzyme (ACE inhibitor). ACE kev tsuj tawm ua rau txo qis tsim cov tshuaj angiotensin II (nrog rau cov nyhuv vasoconstrictor) thiab txo qis hauv aldosterone secretion. Lisinopril-Teva tseem thaiv cov khoom tawg ntawm bradykinin, ib qho muaj zog vasodepressor peptide.Raws li qhov tshwm sim, nws txo cov ntshav siab, tag nrho peripheral vascular tsis kam, ua ntej- thiab tom qab ua haujlwm ntawm lub siab, nce feeb ntau ntau, ua rau lub plawv mob thiab nce myocardial thev taus mus rau cov thauj khoom thiab txhim kho ntshav muab rau ischemic myocardium. Hauv cov neeg mob uas muaj mob myocardial infarction, Lisinopril-Teva, ua ke nrog nitrates, txo kev tsim ntawm sab laug ventricular kawg los yog lub plawv tsis ua haujlwm.

- mob plawv tsis ua hauj lwm (ua ib feem ntawm txoj kev kho mob nrog diuretics thiab mob glycosides)

- mob ncauj lus myocardial infarction rau cov neeg mob uas muaj hemodynamics ruaj khov uas tsis muaj cov cim qhia ntawm lub raum tsis ua haujlwm.

Tsuas tshuaj thiab tswj hwm

Kev kho mob yuav tsum pib nrog 5 mg txhua hnub thaum sawv ntxov. Cov koob tshuaj yuav tsum tau teeb tsa nyob rau hauv xws li txoj hauv kev los muab kev tswj hwm ntshav siab kom zoo. Lub sijhawm nruab nrab ntawm lub sijhawm nce ntxiv yuav tsum yog tsawg kawg 3 lub lis piam. Qhov kev saib xyuas niaj zaus yog 10-20 mg ntawm lisinopril 1 zaug hauv ib hnub, thiab qhov siab tshaj plaws txhua hnub yog 40 mg 1 zaug nyob rau ib hnub.

Lisinopril-Teva tau kho ntxiv rau kev kho mob uas twb muaj lawm nrog diuretics thiab digitalis. Thawj qhov tshuaj yog 2.5 mg thaum sawv ntxov. Cov koob tshuaj txij nkawm yuav tsum tau tsim nyob rau hauv cov qib nrog nce ntawm 2.5 mg nrog ib nrab ntawm 2-4 lub lis piam. Cov koob tshuaj saib xyuas li niaj zaus yog 5-20 mg ib hnub ib zaug. Tsis txhob noj ntau tshaj qhov ntau tshaj 35 mg ntawm lisinopril / hnub.

Mob myocardial infarction rau cov neeg mob uas muaj hemodynamics ruaj khov:

Kev kho mob nrog lisinopril-Teva tuaj yeem pib hauv 24 teev tom qab pib pom cov tsos mob, muab cov hemodynamics ruaj khov (systolic ntshav siab ntau dua 100 mmHg, tsis muaj cov cim ntawm lub raum tsis ua haujlwm), ntxiv rau txoj kev kho mob rau lub plawv nres (thrombolytic cov neeg sawv cev, acetylsalicylic acid, beta-blockers, nitrates). Thawj koob tshuaj yog 5 mg, tom qab 24 teev - lwm 5 mg, tom qab 48 teev - 10 mg. Tom qab ntawd qhov koob tshuaj yog 10 mg ntawm lisinopril 1 zaug hauv ib hnub.

Cov neeg mob uas tsis tshua systolic ntshav siab (≤ 120 mm Hg) ua ntej kho lossis thaum thawj 3 hnub tom qab lub plawv nres yuav tsum tau txais kev kho qis dua 2.5 mg ntawm Lisinopril-Teva rau kev kho mob. Yog tias systolic siab tsawg dua 90 hli Hg. Kos duab. ntau dua 1 teev yuav tsum tso cov lisinopril-Teva.

Txoj kev kho yuav tsum txuas ntxiv rau 6 lub lis piam. Qhov tsawg kawg nkaus txij nkawm tshuaj yog 5 mg ib hnub twg. Cov neeg mob uas muaj cov tsos mob ntawm lub plawv tsis ua hauj lwm yuav tsum tau kho nrog lisinopril-Teva. Cov tshuaj yuav muab tau ib txhij nrog nitroglycerin (tso ntshav los yog daim tawv nqaij tawv ib daim).

Thaum muaj myocardial infarction, lisinopril yuav tsum tau muab rau ntxiv rau qhov kev kho mob ib txwm muaj (cov neeg muaj kab mob, acetylsalicylic acid, beta-blockers), nyiam dua ua ke nrog nitrates.

Hauv cov neeg mob laus, qhov ntau npaum yuav tsum tau hloov kho mus rau hauv tus account qib creatinine (txhawm rau tshuaj xyuas lub raum kev ua haujlwm), uas yog xam los ntawm tus qauv Cockroft:

(140 - hnub nyoog) × lub cev hnyav (kg)

0.814 × cov yeeb yaj kiab creatinine concentration (μmol / L)

(Rau cov poj niam, qhov tshwm sim tau los ntawm cov qauv no yuav tsum tau khoo 0.85).

Tsuas noj rau hauv cov neeg mob uas muaj mob me me lub raum kev ua haujlwm (kev tsim tej yam ua paug 30 - 70 ml / min):

Thawj koob tshuaj yog 2.5 mg thaum sawv ntxov, qhov tshuaj txij nkawm yog 5-10 mg ib hnub twg. Tsis txhob noj ntau tshaj qhov ntau kawg ntawm 20 mg ntawm lisinopril ib hnub.

Lisinopril-Teva tuaj yeem nqa tsis hais cov pluas noj, tab sis nrog cov kua txaus, 1 zaug nyob rau ib hnub, nyiam dua nyob rau tib lub sijhawm.

Cov tshuaj sib cuam tshuam

Nrog tib lub sijhawm siv ntawm Lisinopril-Teva ntsiav tshuaj thiab:

- lithium tuaj yeem txo cov roj ntsha lithium kom tsis txhob nkag los ntawm lub cev, yog li ntawd, nws yuav tsum ua tib zoo saib xyuas kom cov concentration ntawm lithium hauv cov ntshav cov ntshav

- analgesics, non-steroidal anti-inflammatory tshuaj (piv txwv li, acetylsalicylic acid, indomethacin) - nws muaj peev xwm ua kom tsis muaj zog hypotensive nyhuv ntawm lisinopril

- baclofen - nws yog qhov ua tau los txhim kho cov kev ua haujlwm hypotensive ntawm lisinopril-diuretics - nws yog qhov ua tau kom nce cov nyhuv hypotensive ntawm lisinopril

- potassium-sparing diuretics (spironolactone, triamteren lossis amiloride) thiab cov tshuaj potassium ntxiv rau qhov kev pheej hmoo ntawm hyperkalemia

- antihypertensive tshuaj - tuaj yeem txhim kho qhov ntxim siab hypotensive ntawm lisinopril

- Tshuaj loog, tshuaj, pw kom tsaug zog - tej zaum ntshav nce siab

- allopurinol, cytostatics, immunosuppressants, systemic corticosteroids, procainamide - qhov kev pheej hmoo ntawm kev tsim leukopenia nce

- cov tshuaj tiv thaiv kab mob hauv lub qhov ncauj (sulfonylurea derivatives, biguanides) thiab tshuaj insulin - nws yog qhov muaj peev xwm los ua kom cov nyhuv hypotensive, tshwj xeeb tshaj yog nyob rau thawj lub lis piam ntawm kev kho mob sib xyaw.

- amifostine - hypotensive nyhuv yuav kho kom zoo dua

- antacids - txo lub cev ntawm lisinopril

- sympathomimetics - hypotensive nyhuv yuav kho kom zoo dua

- haus dej cawv - muaj cov cawv ntau heev tuaj

- sodium chloride - lub zog ntawm cov nyhuv hypotensive ntawm lisinopril thiab qhov tshwm sim ntawm cov tsos mob ntawm lub plawv tsis ua haujlwm.

Daim ntawv tso tawm

Cov tshuaj yog nyob rau hauv daim ntawv ntawm ntsiav tshuaj. Tsis hais txog ntawm qhov kev kub siab, lawv muaj nyob rau hauv oval biconvex duab thiab cov xim dawb. Muaj kev pheej hmoo ntawm ib sab ntawm cov tshuaj noj, ntawm ib sab yog tus txua “LSN2.5 (5, 10, 20)”.

Cov yam ntxwv ntawm kev nqis tes ua nyob ntawm kev saib xyuas los ntawm cov tshuaj nquag hauv yeeb tshuaj. Tsis hais txog ntawm cov txiaj ntsig no, cov ntsiav tshuaj tau ntim rau hauv cov hlwv ntim ntawm 10 daim. Thaum muab qhov ntau npaum ntawm 2.5 mg, 3 daim hlau no tau muab tso rau hauv ib pob, 5 mg - 1 lossis 3 daim. Tshuaj tua kab mob ntawm 10 thiab 20 mg yog muag hauv 1, 2 lossis 3 blisters ib pob.

Tshuaj ua

Lisinopril inhibits qhov kev hloov pauv ntawm angiotensin-hloov pauv, uas yog lub hauv paus rau kev tawg ntawm angiotensin I mus rau angiotensin II. Yog li ntawd, aldosterone synthesis thiab peripheral vascular tsis kam, thiab prostaglandin ntau lawm ntau zog. Cov nyhuv no ua rau txo qis hauv ntshav siab, nias siab hauv cov hlab ntsws cov hlab ntsha thiab preload, nce ntxiv ntawm cov feeb ntawm cov ntshav ntws.

Kev noj tshuaj pab txhim kho cov ntshav muab rau cov leeg ischemic. Lub sij hawm ntev kho tuaj yeem txo myocardial hypertrophy. Hauv cov neeg mob uas muaj lub plawv tsis ua haujlwm ntev, lub neej yuav nce ntxiv. Yog tias qhov mob plawv sai tau raug mob, tab sis lub siab tsis ua haujlwm tsis pom nrog lub chaw kuaj mob, tom qab ntawd nrog kev siv tshuaj, sab laug ventricular kawg hloov zuj zus qeeb dua.

Hauv thawj hnub ntawm kev kho, qhov ua kom siab zoo ntawm cov tshuaj yog pom tau. Nws mus txog qhov kev nyab xeeb nyob rau hauv 1-2 lub hlis ntawm kev haus cov tshuaj tas li.

Nws yuav tsum tau yug hauv siab tias qee qhov pathologies tuaj yeem cuam tshuam qhov chaw muag tshuaj ntawm cov tshuaj:

• txo qis hauv kev tshem tawm, kev nqus thiab bioavailability (16%) nyob rau hauv muaj cov kev mob plawv tsis ua haujlwm,
• ntau zog thaum lub sij hawm ua kom cov concentration ntawm lisinopril hauv ntshav nrog lub raum tsis ua hauj lwm,
• 2 lub sij hawm ntau dhau ntshav tsom hauv lub hnub nyoog laus,
• 30% txo hauv bioavailability thiab 50% tshem tawm los tiv thaiv mob qog.

Sab Phiv, noj ntau dhau

Cov kev phiv tsis zoo thaum noj Lisinopril-Teva tau muab faib ua pawg raws li qhov ntau zaus ua kom pom tseeb. Ntau zaus, cov kev kho zoo li no ua rau cov kev rau txim hauv qab no:

• orthostatic hypotension,
• hais txo nyob rau hauv siab,
• kiv tob hau, mob taub hau,
• hnoos
• ntuav
• zawv plab
• tsis hnov ​​mob raum muaj nuj nqi.

Qhov ntau npaum yuav tsum tau xaiv los ntawm tus kws tshaj lij. Yog tias qhov raug xaiv tsis zoo lossis tshaj qhov ntim tau pom zoo, ntau cov kev mob tshwm sim tuaj yeem ua tau.

Feem ntau, kev noj ntau dhau yog qhia los ntawm cov tsos mob hauv qab no:

• siab tseem ceeb poob
• qhov ncauj qhuav
• dej-electrolyte tsis txaus,
• lub raum tsis ua hauj lwm
• pa ceev heev
• palpitations
• kiv taub hau
• ntxhov siab
• nce siab txob taus
• tsaug zog
• bradycardia
• hnoos
• kev tso zis cia
• cem quav
• hyperventilation ntawm lub ntsws.

Tsis muaj ib qho tshuaj tshwj xeeb rau kev kho mob ntawm kev haus luam yeeb dhau. Nws yog ib qho tsim nyog yaug lub plab, kom ntseeg tau qhov kev nkag ntawm enterosorbent thiab laxative. Txoj kev zaws kuj tseem cuam tshuam txog kev tswj hwm cov dej qab ntsev. Yog hais tias bradycardia tiv taus kev kho mob, chaw rau nruab ib qho khoom cua nrawm. Siv cov tshuaj hemodialysis zoo.

Sib piv nrog lwm cov tshuaj, cawv

Nws yog qhov ua tau ntawm kev nqis tes ntawm lisinopril yog ua kom zoo dua nrog kev siv tshuaj diuretic ib zaug los yog kev coj ua ntawm lwm yam tshuaj tiv thaiv kab mob siab. Siv cov vasodilators, barbiturates, tricyclic antidepressants, calcium antagonists, β-blockers tuaj yeem ua rau muaj txiaj ntsig zoo sib xws. Cov txiaj ntsig rov qab raug pom thaum ua ke nrog acetylsalicylic acid, sympathomimetics, estrogens lossis tshuaj ntawm ib pawg tsis-steroidal anti-inflammatory pawg.

Kev tswj hwm tib lub sijhawm ntawm Lisinopril-Teva thiab cov tshuaj kho ntawm cov pab pawg potassium-sparing los yog cov tshuaj potassium npaj tuaj yeem ua rau hyperkalemia. Ua ke nrog cov tshuaj insulin lossis ib tus neeg sawv cev hypoglycemic tuaj yeem ua rau hyperglycemia.

Cov dej cawv lossis tshuaj yeeb uas muaj ethanol txhim kho cov nyhuv ntawm lisinopril.

Txee lub neej, chaw cia khoom

Kev khaws cia ntawm cov tshuaj yuav tsum tau nqa tawm hauv ib qho chaw uas nkag tsis tau rau cov menyuam yaus ntawm qhov kub tsis tshaj 25 degrees. Yog tias cov mob no tau ua tiav, cov tshuaj tuaj yeem siv tsis pub dhau 2 xyoos txij li hnub ntawm nws cov chaw tsim khoom.

Tus nqi nruab nrab rau ib pob ntawm Lisinopril-Teva 2.5 mg lossis 5 mg yog 125 rubles. Cov tshuaj 10 mg raug nqi qhov nqi nruab nrab ntawm 120 rubles rau 20 daim thiab 135 rubles rau 30 daim. Ib qho tshuaj 20 mg yuav raug nqi li 150 rubles rau 20 ntsiav tshuaj thiab 190 rubles rau 30 ntsiav tshuaj.

Kev yuav khoom, koj yuav tsum muab cov kws muag tshuaj nrog cov kws kho mob sau ntawv los yuav.

Lisinopril-Teva muaj ntau cov qauv yeeb yam. Tag nrho cov ntawm lawv yog nyob ntawm ib yam tshuaj uas muaj sia - lisinopril. Cov tshuaj no suav nrog:

• Aurolyza,
• Diroton
• Dag
• Vitopril
• Lysoryl
• Lizi Sandoz,
• Zonixem
• Lysinokol
• Lisopril
• Dapril
• Lysigamma
• Pob Tsuas Xyooj
• Irumed
• Lisighexal
• Solipril
• Linotor.

Lisinopril-Teva inhibits cov enzyme angiotensin-hloov pauv, muab cov kev cuam tshuam nyuaj. Siv tshuaj yuav tsum yog ntawv sau los ntawm kws kho mob nruj me ntsis hauv lub ntim teev, txwv tsis pub tshaj plaws yog ua tau. Thaum ua ke nrog lwm cov tshuaj, qhov sib zog ntawm cov nyhuv ntawm lisinopril yuav txawv.

Txujci thiab kev thov nta

Cov tshuaj Lisinopril-Teva yog siv los ntawm kev nqos qhov yuav tsum tau muab ntawm cov ntsiav tshuaj nrog cov kua txaus. Cov koob tshuaj txhua hnub yog sib npaug rau ib ntsiav tshuaj, uas yuav tsum tau noj kom thoob plaws hauv chav kawm txoj kev kho ib zaug ib hnub thiab tib lub sijhawm, tsis txhob ua tib zoo noj mov. Cov tshuaj rau txhua tus neeg mob yog xaiv los ntawm tus kws kho mob koom nrog tus kheej ib tus zuj zus.