Tshuaj Insulin Vozulim n: kev txiav txim ntawm tshuaj yaj yeeb recombinant

• 1 Txheej Txheem thiab Daim Ntawv Tso Tawm
• 2 mechanism ntawm kev txiav txim
• 3 Qhov ntsuas qhov siv
• 4 Cov lus qhia rau kev siv "Manil" nyob rau hauv cov ntshav qab zib
• 5 Siv thaum cev xeeb tub thiab lactation
• 6 Siv rau menyuam yaus thiab hnub nyoog laus
• 7 Cov Kev Txwv Tsis Pub Thaiv
• 8 kev phiv
• 9 Khuv Xim dua
• 10 Kev sib cuam tshuam nrog lwm txoj kev
• 11 Cov xwm txheej ntawm hnub so thiab chaw cia khoom
• 12 Cov Tshuaj Kho Mob analogues
• 13 Raug Mob thiab Nyiaj Pab

Txog kev kho mob pob qij txha, peb cov neeg nyeem tau siv DiabeNot siv tau zoo. Pom qhov nrov ntawm cov khoom no, peb tau txiav txim siab muab nws rau koj kom txaus siab.

Maninil cov tshuaj kho mob yog siv los kho hom 2 mob ntshav qab zib mellitus yog tias kev noj zaub mov zoo thiab kev tawm dag zog lub cev tsis tau coj cov nyhuv hypoglycemic. Txawm hais tias qhov tseeb tias cov tshuaj muaj txiaj ntsig zoo, nws kuj tseem muaj qee qhov tsis zoo, yog li, ua ntej siv nws, nws yog ib qho tseem ceeb kom sab laj nrog koj tus kws paub txog kev noj qab haus huv.

Kev Sib Sau thiab daim ntawv ntawm kev tso tawm

Kev noj tshuaj rau qhov mob ntshav qab zib Maninil yog tsim tawm hauv cov ntsiav tshuaj liab. Cov tshuaj ua kom nquag plias yog glibenclamide ntau npaum li ntawm 1.75, 3.5 thiab 5 milligrams, nyob ntawm seb ntau npaum li cas. Cov khoom siv ntxiv yog cov lactose monohydrate, hmoov txhuv nplej siab, magnesium stearate thiab silicon dioxide. Muaj cov tshuaj hauv lub hwj tshuaj txog 120 daim.

Rov qab rau cov lus txheej txheem

Mechanism ntawm kev ua

Siv cov tshuaj nquag uas yog ib feem ntawm Maninil, nws muaj peev xwm nce insulin rhiab heev, nce nws tso tawm, thiab txhim kho cov nyhuv ntawm insulin rau ntawm kev nqus ntawm cov piam thaj los ntawm lub siab. Tsis tas li, cov tshuaj txo qis ntawm cov khoom muaj zog ntawm cov ntshav. Kev txo cov piam thaj hauv lub cev tshwm sim 2 teev tom qab kev tswj hwm thiab kav ntev li ib hnub.

Rov qab rau cov lus txheej txheem

Kev ntsuas rau siv

Feem ntau, cov tshuaj yog siv los kho tshuaj insulin-tiv thaiv ntshav qab zib hom 2 thiab tswj ntshav qabzib. Nws tseem tseem sau tseg thaum nws tshwm sim:

• poob hauv cov neeg mob uas rog dhau,
• kuaj mob hyperglycemia.

Rov qab rau cov lus txheej txheem

Cov lus qhia rau kev siv "Manil" nyob rau hauv cov ntshav qab zib

Cov tshuaj tau noj nrog dej txaus.

Cov tshuaj ntshav qab zib yog noj ua ntej noj mov, thaum nws tsis tas yuav tsum zom thiab yuav tsum tau ntxuav nrog qhov dej txaus. Nws yog tsuas yog sau ntawv rau ib hnub ib zaug (sawv ntxov thaum sawv ntxov). Yog tias tus neeg mob tsis nco qab noj tshuaj, qhov no yuav tsum tau ua kom sai li nws nco qab nws. Nyob rau tib hnub, nws yog txwv tsis pub noj ob zaug tshuaj ntawm cov tshuaj.

Qhov ntau thiab tsawg ntawm cov tshuaj yog ncaj qha ntsig txog lub hnub nyoog ntawm tus neeg mob, qhov degree ntawm cov chav kawm ntawm tus kab mob thiab cov ntshav qab zib theem. Thawj theem pib ntawm kev kho ntshav qab zib koom nrog kev siv ib lossis 2 ntsiav tshuaj ib hnub ib zaug. Yog tias qhov ntau npaum no tsis muab cov nyhuv xav kho, nws tuaj yeem nce ntxiv nyob hauv kev saib xyuas nruj ntawm cov kws kho mob. Hauv qhov no, qhov koob tshuaj tau nce zuj zus. Nws raug tso cai kom haus tsis ntau tshaj 5-6 ntsiav tshuaj hauv ib hnub.

Rov qab rau cov lus txheej txheem

Siv thaum cev xeeb tub thiab lactation

Cov tshuaj rau ntshav qab zib "Maninil" 5 thiab nws lwm cov ntawv tsis raug sau tseg thaum cev xeeb tub thiab lactation. Cov neeg ua hauj lwm pab kev noj qab haus huv tau ceeb toom tias nws yog ib qho tseem ceeb uas yuav tsum siv txoj kev tswj kom tsis txhob muaj me nyuam nyob rau hauv txoj kev kho mob kom tsis txhob muaj menyuam. Yog tias cev xeeb tub tshwm sim, kev siv tshuaj yuav tsum nres tam sim ntawd.

Rov qab rau cov lus txheej txheem

Siv rau lub sijhawm menyuam yaus thiab hnub nyoog laus

Cov lus qhia rau kev siv tsom mus rau qhov tseeb tias cov tshuaj "Maninil", siv los kho ntshav qab zib, raug txwv tsis pub siv rau cov menyuam yaus hnub nyoog qis dua 18 xyoo. Daim ntawv thov hauv hnub nyoog laus yog kev tso cai, tab sis yuav tsum tau nqa tawm los ntawm kev saib xyuas tas li ntawm cov kws kho mob. Tsis tas li ntawd, qhov kev pib ntawm thawj cov tshuaj yuav tsum raug txo qis, txij li kev pheej hmoo ntawm hypoglycemia (qhov txo qis ntawm cov piam thaj hauv lub cev) tsis cais.

Rov qab rau cov lus txheej txheem

Cov Yuav Tsum Muaj

Kev cuam tshuam ntawm cov hnyuv yog qhov ua tsis zoo rau kev noj tshuaj.

Nws raug txwv tsis pub noj tshuaj rau ntshav qab zib yog tias pom tias tus neeg mob:

• tsis kam txais qee yam yeeb tshuaj,
• ntshav qab zib hom 1
• ketoacidosis
• coma
• kev ntxhov siab hauv cov haujlwm ntawm lub siab,
• raum tsis ua hauj lwm
• hemopoiesis mob ntshav dawb,
• ob leeg plob tsis so tswj,
• lactose thev tsis tau.

Tus neeg sawv cev kws kho mob muab ntawv pov thawj nrog qhov tseeb yog qhov kev hloov pauv raug pom:

• cov thyroid pathology,
• npaws
• malfunctioning ntawm adrenal cortex,
• quav cawv
• haus dej cawv lom
• muaj hnub nyoog dhau los ntawm 70 xyoo.

Rov qab rau cov lus txheej txheem

Sab sij huam

Qee zaum "Maninil" ua rau muaj cov kev mob tshwm sim:

Xeev siab yog ib qho kev phiv los ntawm txoj kev noj tshuaj.

1. Lub plab zom mov:
   • bouts ntawm xeev siab
   • ntxhoo
   • mob hauv lub plab
   • saj ntawm hlau nyob rau hauv lub qhov ncauj kab noj hniav,
   • piam thaj txo qis
   • hnyav.
2. Daim tawv nqaij:
   • khaus thiab hlawv
   • pemphigus
   • kev nkag siab zoo rau ultraviolet hluav taws xob,
   • mob leeg
   • mob tej pob txha
   • dajntoo
   • Quincke's edema.
3. Hematopoietic kabmob:
   • platelet suav txo,
   • neeg tsis muaj zog cov qe ntshav dawb,
   • txo nyob rau hauv tag nrho cov naj npawb ntawm cov ntshav liab,
   • qhov poob hauv cov qe ntshav dawb.
4. Dav:
   • mob taub hau
   • tsis muaj zog
   • kev xav ntawm kev ntxhov siab
   • cramps
   • tsis meej pem ntawm kev tsiv
   • ua txhaum lub cev thiab hais lus.

Rov qab rau cov lus txheej txheem

Noj ntau dhau

Nrog kev noj tshuaj ntau dhau, lub cev kub nce ntxiv.

Thaum tus neeg noj ntau dhau lawm, tus neeg mob muaj cov tsos mob li nram no:

• nce qab los noj mov
• npaws
• kev txawv txav ntawm lub plawv
• kev xav ntawm kev ntxhov siab
• mob taub hau
• ua txhaum ntawm kev pom thiab hais lus lub zog.

Yog tias pom muaj cov tsos mob zoo ib yam, nws yog ib qho tseem ceeb kom noj ib qho qab zib lossis ib pluag mov uas muaj qabzib sai li sai tau. Yog tsaus muag tau tshwm sim, cov suab thaj nyob hauv cov ntshav khov.

Rov qab rau cov lus txheej txheem

Sib cuam tshuam nrog lwm txoj kev

Nrog rau kev siv cov tshuaj ib txwm nrog anabolics, cov tshuaj uas tsis yog tshuaj steroidal, ACE inhibitors, lwm yam tshuaj hypoglycemic thiab beta-blockers, qhov nce ntawm cov nyhuv ntawm cov tshuaj yog tsom txo qis dua ntawm cov piam thaj. Kev txo qis ntawm kev ua haujlwm ntawm Maninil tshwm sim nrog ib daim ntawv thov nrog barbiturates, glucocorticoids, diuretics ntawm thiazide pawg, qhov ncauj tshuaj tiv thaiv thiab tshuaj, uas suav nrog lithium.

Rov qab rau cov lus txheej txheem

So haujlwm thiab chaw mob

Koj tuaj yeem yuav cov tshuaj "Maninil" hauv cov tsev muag tshuaj txuas tshwj xeeb raws li kws kho mob sau ntawv yuav tshuaj, uas muaj ntawv pov thawj. Cov lus qhia rau kev siv qhia tias cov khoom yuav tsum tau muab cia rau hauv qhov chaw qhuav, qhov kub nyob hauv qhov uas yuav tsis siab tshaj 30 degrees. Chav no yuav tsum tsis pub nkag rau cov tsiaj, menyuam yaus thiab tshav ntuj ncaj qha. Lub sijhawm tso cia yuav tsum tsis pub tshaj 3 xyoos txij li hnub ntawm kev tsim khoom, hnub tim uas tau qhia rau ntawm daim ntawv ntim khoom.

Rov qab rau cov lus txheej txheem

Kev ntsuas tshuaj ntawm cov kws tshuaj

Glibenclamide suav hais tias yog ib qho tshuaj noj tshuaj.

Tsuas yog siv tshuaj yeeb yaj kiab, uas suav nrog tib yam tshuaj muaj zog xws li hauv Maninil, suav tias yog tshuaj Glibenclamide. Lwm cov tshuaj lag luam uas muaj cov nyhuv hauv lub cev tsis tseem ceeb muaj cov qauv zoo sib xws ntawm lub cev, tab sis lwm cov tshuaj nquag. Nws yog ib qho tseem ceeb kom nco ntsoov tias nws yog nruj me ntsis txwv tsis pub hloov Maninil nrog nws cov tshuaj analogue ntawm nws tus kheej, vim tias cov kev ntsuas no tsis tsuas yog pab tsis tau rau kev kho mob ntshav qab zib mellitus, tab sis kuj tseem yuav ua mob loj rau koj kev noj qab haus huv.

Rov qab rau cov lus txheej txheem

Txoj Cai thiab Kev Pab

"Maninil" rau cov ntshav qab zib yog nquag sau tseg hauv kev kho mob thiab suav hais tias yog ib qho tshuaj zoo. Nws pab tsis tsuas yog muaj cov piam thaj hauv siab, nws kuj tseem raug rau cov neeg noj qab haus huv kom tswj tau cov ntshav qabzib. Txawm li cas los xij, txawm hais tias nws ua tau zoo ntawm cov txheej txheem kev kho mob, nws tseem muaj qhov tsis zoo hauv cov qauv ntawm tus naj npawb txaus ntawm contraindications thiab phiv. Ib qho ntawm qhov hnyav tshaj plaws ntawm lawv yog kev tsim cov ntshav khov (hypoglycemia), uas ua rau lub cev tsis zoo.

Tshuaj Insulin Vozulim n: kev txiav txim ntawm tshuaj yaj yeeb recombinant

Kev npaj tshuaj insulin yog siv los hloov kev kho mob hauv cov neeg mob ntshav qab zib. Lawv muab faib los ntawm lub sijhawm ua ntawm kev ua luv luv thiab txuas ntxiv. Lub sijhawm tiv thaiv ntawm tus neeg sib txawv yog tus neeg. Yog li, kev xaiv cov tshuaj insulin feem ntau yog ua hauv tsev kho mob.

Txog rau qhov no, tswj theem ntawm glycemia thaum nruab hnub. Tom qab ntawd tus kws kho mob sau cov tshuaj ntawm cov tshuaj insulin raws li tus nqi metabolic, noj zaub mov, ua si lub cev, ua ke ntawm cov tshuaj sib txawv.

Cov nyiaj pab cuam cov khoom noj uas tau nyiaj pab cuam tas mus li, hloov pauv txhua hnub tsawg dua hauv cov ntshav qabzib, thiab, yog li, txo qis kev pheej hmoo ntawm kev mob ntshav qab zib.

Cov cai yooj yim rau kev kho tshuaj insulin

Nquag, 23-59 IU ntawm insulin yog tsim, qhov no yog kwv yees li 1 kg ntawm lub cev qhov hnyav - 0.6 - 1.0 UNITS. Qhov kev zais no tau muab faib ua qhov chaw hauv qab daus thiab zaub mov (bolus). Cov kua dej zais cia tsis pub dhau yog li ntawm 1 ib xuab moos twg. Tsim los ntawm cov khoom noj, tsim khoom thiab tso tawm cov tshuaj insulin - 1 chav rau txhua 10 lossis 12 g ntawm carbohydrates (1XE).

Qhov kev xav tau ntawm cov kua dej yog ntau dua thaum sawv ntxov, thiab qhov rhiab heev rau nws thaum yav tsaus ntuj. Qhov no yog qhov tseem ceeb rau kev teeb tsa lub sijhawm tswj kev siv tshuaj, txij li lub hom phiaj ntawm kev kho tshuaj insulin yog los sim cov tshuaj insulin npaj ntawm cov sib txawv ntawm lawv tus kheej lub zais cia.

Hom no yog hu ua lub hauv paus-bolus hauv paus ntsiab lus ntawm insulin tswj hwm. Nws qhov kev nkag siab zoo kev kho mob insulin thiab kev siv cov tshuaj insulin. Tsim kho cov tshuaj insulin kom tsis pub dhau ntawm qhov tsis suav, tshwj tsis yog rau carbohydrates (piam thaj), amino acids thiab cov protein.

Qhia tshuaj insulin muaj qhov sib txawv ntawm kev nqus, uas nyob ntawm ntau yam xws li:

Qhov tseem ceeb tshaj ntawm cov no yog cov hauv qab no:

• Qhov kub ntawm insulin npaj, nws cov solubility.
• Qhov ntim ntawm cov tshuaj txhaj.
• Thaj chaw ntawm kev txhaj tshuaj (nrawm dua ntawm daim tawv nqaij ntawm lub plab, qeeb qeeb los ntawm ncej puab lossis xub pwg).
• Lub cev qoj ib ce.
• Tus neeg mob cov mob hlwb

Lub hom phiaj ntawm kev kho mob insulin: Vozulim N, cim qhia

Cov tshuaj insulin yog tsim nyob rau hauv thiaj li yuav ua kom cov metabolism zoo. Qhov tsim nyog, qhov no txhais tau tias ua tiav qhov kev yoo ntshav khov sai, tiv thaiv qhov nce siab tom qab noj mov, yuav tsum tsis muaj cov piam thaj hauv cov zis, tsis muaj kev tawm tsam ntawm kev mob ntshav qab zib.

Qhov txaus siab ua piv txwv ntawm txoj kev kho kom zoo yog kev txo qis lossis tshem tawm cov tsos mob tseem ceeb ntawm ntshav qab zib, tsis muaj ketoacidosis, hyperglycemia loj heev, muaj kev tawm tsam ntawm ntshav qab zib tsawg.

Txog kev kho mob pob qij txha, peb cov neeg nyeem tau siv DiabeNot siv tau zoo. Pom qhov nrov ntawm cov khoom no, peb tau txiav txim siab muab nws rau koj kom txaus siab.

Kev kho tshuaj Insulin tso cai rau koj los tswj lub cev qhov hnyav ntawm cov neeg mob thiab noj zaub mov uas muaj cov khoom noj carbohydrates (tshwj tsis yog cov yooj yim), tswj kom muaj ib feem ntawm lipoproteins, roj cholesterol.

Lub hom phiaj kawg ntawm kev kho mob insulin yog ib txwm kev ua neej, muaj peev xwm ua kom muaj kev sib cuag sib cuag. Kev siv lub sijhawm tsis raug thiab kev tswjhwm ntawm insulin pab tiv thaiv lossis txo qis cov leeg hlwb thiab leeg ntshav ntawm cov kab mob.

Cov cim tseem ceeb rau kev muab tshuaj rau cov tshuaj insulin rau ntshav qab zib yog:

1. Thawj hom ntshav qab zib.
2. Ketoacidosis (sib txawv hauv qhov loj).
3. Coma: hyperosmolar, ketoacidotic, lactic acidosis.
4. Kev kis mob ntawm mob hnyav thiab mob loj dhau los.
5. Tub Ntshaw
6. Poob ceeb thawj sai.
7. Rov ua dua li tus mob pancreatitis, mob caj dab, Mob caj pas, pancreatic necrosis.

Kev siv tshuaj insulin tsis hais txog hom ntshav qab zib nyob rau hauv qhov muaj mob microangiopathies nrog lub cev ua haujlwm tsis zoo, mob ntshav tsis txaus ntawm lub hlwb thiab myocardial infarction, kev phais mob mus ntxiv.

Hauv hom 2 mob ntshav qab zib mellitus, insulin kuj tseem qhia txog kev tawm tsam tshuaj hauv qhov ncauj thiab mob ntshav qab zib ntau dhau los, nws yog siv rau thaum tsis mob ntshav qab zib.

Yuav ua li cas sau Vozulim N?

Cov tshuaj yog tib neeg cov tshuaj insulin, isofan, tau los ntawm kev tsim tshuaj tua kab. Daim ntawv tsuas tshuaj yog ncua rau kev tswj hwm hauv qab daim tawv nqaij. Ib qho milliliter muaj 100 PIECES ntawm insulin. Muaj nyob rau hauv 10 ml vials thiab cartridges nrog lub ntim ntawm 3 ml.

Txhawm rau nkag mus rau Vozulim N, koj yuav tsum paub txog kev txhaj tshuaj insulin kom raug. Ua ntej cov lus qhia, koj yuav tsum noj lub vial los ntawm lub tub yees hauv 30 feeb. Kuaj cov hnub tim thiab hnub tag sijhawm. Cov tshuaj uas tas sij hawm los sis qhib ntau dua 28 hnub dhau los yuav muab tsis tau.

Qhov kev txhaj tshuaj yuav tsum tau ua tsuas yog ntxuav thiab ntxuav tes ntawm daim tawv nqaij huv (cawv yuav tsum tsis txhob rub tawm). Lub taub tshuaj insulin Vozulim N xav kom muab dov rau hauv txhais tes kom cov xim ntawm kev ncua yuav ua rau xim dawb, huab.

Yog tias kev txhaj tshuaj yog ua nrog lub koob txhaj tshuaj, yuav tsum ua raws li txoj cai hauv qab no:

• Tsis txhob kov rab koob nrog tej nplaim.
• Ua tib zoo xyuas lub koob tshuaj ntawm cov tshuaj insulin.
• Qhov chaw txhaj tshuaj yuav tsum tsis txhob nyob ze rau ntawm cov moles (ze dua 2,5 cm) lossis ntaws ntaws, koj tsis tuaj yeem tawv ncauj rau ntawm qhov chaw raug mob lossis o.
• Tom qab txhaj tshuaj, cov koob txhaj tshuaj yuav tsum nyob hauv qab daim tawv nqaij li 5 feeb.
• Lub koob thiab koob txhaj tshuaj yuav tsum tau muab pov tseg kom zoo tom qab kev txhaj tshuaj.

Nrog rau kev qhia ntawm cov tshuaj nrog tus cwj mem syringe, koj yuav tsum teeb tsa lub dispenser ntawm qib xav tau thiab nias lub khawm pib. Tom qab ntawd, tuav tus cwj mem rau kaum feeb tsis tas tshem nws tawm ntawm daim tawv nqaij. Qhov siv koob yuav tsum tau muab pov tseg tam sim ntawd.

Qhov chaw txhaj tshuaj yuav tsum tau hloov, ua ib tus qauv rau koj tus kheej. Txo kom mob siab, koj yuav tsum muaj rab koob nyias thiab luv.

Vulim N ua li cas tom qab kev tswj hwm?

Vozulim N yog qhov nruab nrab-lub sijhawm cov tib neeg siv tshuaj insulin. Txhawm rau pib txo qis ntshav qab zib, nws yuav tsum txuas mus rau ib qho kev txais tshwj xeeb rau ntawm daim nyias nyias ntawm tes. Vozulim N cov lus tsim tawm hauv insulin + receptor complex uas nthuav tawm biochemical intracellular kev tsis haum.

Kev txo qis ntawm glycemia yog txuam nrog kev nqus ntxiv ntawm cov piam thaj los ntawm cov hlwb thiab nws txoj kev koom nrog hauv cov txheej txheem hauv kev zom zaub mov ntawm glycolysis rau lub zog. Cov tshuaj Insulin kuj tseem muaj peev xwm ua kom nrawm nrog kev tsim cov rog thiab glycogen. Hauv cov qog hlwb, tsim kom muaj cov kua nplaum nyob ntev thiab kev rhuav tshem cov khw muag khoom glycogen.

Lub sijhawm ntawm kev ua ntawm insulin Vozulima N yog vim yog tus nqi ntawm kev nqus. Nws nyob ntawm ntau yam: txhaj, hom, qhov chaw tswjhwm. Hauv qhov no, qhov profile ntawm insulin qhov kev txiav txim yuav muaj kev hloov pauv rau ob tus neeg mob sib txawv thiab hauv tib tus neeg.

Cov nyhuv ntawm cov tshuaj pib 1 teev tom qab kev tswj hwm, qhov siab tshaj plaws (ncov) muaj nyob nruab nrab ntawm 2 thiab 7 teev, lub sijhawm ua haujlwm ntawm Vozulima N yog 18-20 teev. Nws yog rhuav tshem los ntawm insulinase hauv daim siab. Nws yog tawm hauv ob lub raum.

Cov yam ntxwv ntawm kev siv Vozulima N:

1. Nws tuaj yeem raug kho rau cov poj niam cev xeeb tub thiab thaum pub niam mis.
2. Qhov kev txhaj tshuaj yog nqa tawm hauv qab daim tawv nqaij, qhov kev daws teeb meem yuav tsum nyob ntawm chav sov.
3. Siv tau cov thawj coj ib txhij nrog luv insulin - Vozulim R.
4. Siv daim cartridge rau rab koob xaum qhuav nkaus xwb.
5. Vim tias qhov ua kom poob qis, siv hauv cov tshuaj insulin twj tsis pom zoo.

Yog tias cov tshuaj insulin raug kho rau thawj zaug lossis tau hloov pauv, nrog qhov kev ntxhov siab ntawm lub cev lossis lub hlwb, ces lub peev xwm txo lub zog los tsav lub tsheb. Kev tswj hwm kev siv tshuab yog ua ib qho muaj txiaj ntsig txaus ntshai.

Yog li ntawd, lawv tsis pom zoo ua haujlwm uas xav tau kev saib xyuas ntxiv, qhov ceev nrawm ntawm lub hlwb thiab lub cev kev xav.

Sab sij huam thiab teeb meem

Kev tswj hwm ntawm cov tshuaj insulin feem ntau ua rau cov ntshav qab zib poob. Cov kev xav ntawm cov neeg mob ntshav qab zib tsis tas ua rau pom tseeb hauv daim duab soj ntsuam. Hauv kev mob ntshav qab zib neuropathy, qhov tseem ceeb tshaj tawm hauv cov ntshav qabzib tsis tuaj yeem lees paub, thiab hauv cov ntshav qab zib uas tsis muaj qab hau, txawm tias qhov glycemia tsawg me ntsis ua rau tsis xis nyob.

Cov tsos mob ntawm tus mob hypoglycemic cuam tshuam nrog kev ua kom ntawm lub siab xav tsis sib luag thiab kev ua kom cov zaub mov tsis txaus rau lub hlwb. Tawm hws, tshaib plab, tshee ob txhais tes, muaj kev ntxhov siab sab hauv, loog ntawm daim di ncauj thiab tus nplaig, tsis muaj zog.

Kev tshwm sim ntawm hypoglycemia tshwm sim vim tias lub hlwb tsis muaj nws cov khw muag ntshav qab zib, thiab thaum cov khoom noj qis, nws cuam tshuam rau hypoxia nrog kiv taub hau, qaug zog, thiab cov khoom noj xav tau. Tom qab ntawd lub paj hlwb raug xa mus rau lub caj pas pituitary, cov tshuaj hormones raug tso tawm. Ib qhov tshuaj tiv thaiv hormonal ua rau kom rov qab hloov kho glycemia.

Txhawm rau kho ntshav qog ntshav hauv thawj theem thiab mus rau qhov tsis txaus, nws yog qhov txaus los noj qab zib, zib ntab, khaub noom, qab zib ntsiav tshuaj. Thaum muaj mob hnyav thiab tsis nco qab zoo, cov neeg mob yuav tsum tau coj mus rau hauv tsev kho mob uas cov ntshav qabzib txhaj tshuaj thiab ntshav qab zib tau txhaj.

Nquag ntshav qab zib ntshav qab zib hauv ntshav qab zib mellitus ua rau muaj kev txhim kho ntawm insulin overdose syndrome (Somogy syndrome). Lub cim kho mob ntawm nws yog raws li nram no:

1. Kev xav tau zoo rau insulin (cuav insulin tsis kam).
2. Lub labile chav kawm ntawm cov ntshav qab zib (pseudolability).
3. Lub cev hnyav los sis hnyav nce nrog glycosuria siab.
4. Txhim kho cov carbohydrate metabolism vim cov kab mob concomitant lossis txo qis dua qhov noj tshuaj.
5. Deterioration ntawm kev zoo nyob nrog qhov nce ntxiv.
6. Ib qho kev xav ntawm kev tshaib plab.
7. Kev hloov pauv hauv cov piam thaj hauv ntshav thiab zis ntau dua.

Kev tawm tsam cov tshuaj insulin tuaj yeem tsim kho, txawm tias ib qho kev txhaj tshuaj ntawm 80 pawg tsis coj qhov ua tau yam xav tau, thiab cov tshuaj tiv thaiv rau cov tshuaj insulin raug tshawb pom hauv cov ntshav. Insulin tsis kam yog ib ntus (nrog decompensation, kis mob, exacerbation ntawm ntev los yog kab mob endocrine) thiab ntev.

Ua xua cov kev tsis haum rau cov tshuaj insulin tau tshwm sim hauv hom Quincke's edema lossis cov dav dav urticaria, lawv tsis tshua muaj. Cov tshuaj tiv thaiv hauv ib cheeb tsam yog cov yam ntxwv hyperemia, o ntawm thaj chaw txhaj tshuaj ntawm insulin lossis khaus tawv. Feem ntau, cov kev qhia hauv cheeb tsam tsis tas yuav kho thiab ploj yam tsis muaj txim.

Lipodystrophy ntawm qhov chaw txhaj tshuaj ntawm inulin, nrog rau cov txheej txheem atrophic hauv cov nqaij mos subcutaneous, thaum tib neeg cov insulin raug txhaj, tshwm sim hauv kev ua txhaum ntawm cov tshuaj insulin, nrog rau cov tshuaj tiv thaiv kab mob hauv cov neeg mob rhiab rau insulin npaj. Txog kev tiv thaiv, koj yuav tsum hloov chaw txhaj tshuaj.

Thaum pib ntawm kev kho mob nrog insulin lossis nrog kev nce ntxiv ntawm cov koob tshuaj siv, insulin edema muaj, uas ploj lawm yam tsis siv cov tshuaj diuretics hauv ib hlis. Qhov no yog cuam tshuam nrog kev txhim kho ntawm cov tshuaj tiv thaiv kab mob thiab sodium retention hauv lub cev.

Xws li edema tuaj yeem tshwm sim hauv lub cev tsis pom kev zoo thaum pib ntawm kev siv tshuaj insulin. Lo ntsiab muag hloov pauv tuab thiab cov neeg mob muaj qhov muag plooj ib ntus thiab nyeem tsis yooj yim. Cov yam ntxwv no tuaj yeem siv tau los ntawm ntau lub lis piam thiab tsis tas yuav kho lossis xaiv cov tsom iav los kho.
Daim vis dis aus hauv tsab xov xwm no qhia cov txheej txheem rau kev siv tshuaj insulin.

Cov yam ntxwv Pharmacological:

Cov Tshuaj Hauv Tshuaj Vozulim-N yog qhov nruab nrab-sijhawm rau tib neeg lub zog cov tshuaj insulin. Nws cuam tshuam nrog kev lees paub tshwj xeeb rau sab nraud cytoplasmic membrane ntawm cov hlwb thiab tsim cov txheej txheem insulin-receptor complex uas txhawb cov txheej txheem intracellular, suav nrog cov synthesis ntawm ntau cov enzymes tseem ceeb (hexokinase, pyruvate kinase, glycogen synthase, thiab lwm yam). Qhov kev txo qis hauv cov ntshav hauv lub cev yog tshwm sim los ntawm kev nce ntxiv hauv nws txoj kev thauj mus los, kev nqus thiab nqus tau los ntawm cov ntaub so ntswg, txhawb kev lipogenesis, glycogenogenesis, qhov txo qis hauv cov ntshav qabzib ntau lawm los ntawm lub siab, thiab lwm yam. , txoj kev thiab qhov chaw tswj hwm), nyob rau hauv kev sib txuas nrog uas cov ntaub ntawv ntawm cov tshuaj insulin yog qhov txawv txav, ob qho tib si hauv tib neeg thiab tib neeg. Qhov pib ntawm kev ua ntawm cov tshuaj yog 1 teev tom qab kev tswj hwm, qhov ua haujlwm siab tshaj plaws yog nruab nrab ntawm 2 txog 8 teev, lub sijhawm ua haujlwm yog 18-20 teev.

Cov Tshuaj Pharmacokinetics Kev ua tiav ntawm kev nqus thiab pib ntawm cov nyhuv ntawm cov tshuaj insulin nyob ntawm txoj kev coj kev tswj hwm (subcutaneously, intramuscularly), qhov chaw tswj hwm (mob plab, ncej puab, pob tw), qhov koob tshuaj (ntim ntawm txhaj tshuaj insulin), cov tshuaj insulin nyob rau hauv cov tshuaj, thiab lwm yam Nws tau faib tsis ncaj ntawm cov ntaub so ntswg thiab tsis hla qhov chaw ntawm lub cev. thiab mus rau hauv niam cov kua mis. Nws yog rhuav tshem los ntawm insulinase feem ntau hauv daim siab thiab lub raum. Nws yog tawm los ntawm lub raum (30-80%).

Tso tawm daim ntawv, muaj pes tsawg leeg thiab ntim khoom

3 ml - cartridges (1) - hlwv pob (1) - pob khoom los ntawm cardboard.
10 ml - fwj (1) - hlwv pob (1) - pob khoom los ntawm cardboard.

Nruab Nrab Sijhawm Insulin (ATX A10AC)

Cov lus ntawm analogues thiab cov nqi

Protafan NM - cov lus qhia ntawm nom rau siv (paub daws teeb)

Muaj cov contraindications. Tham nrog kws kho mob ua ntej noj.

Cov insulin nyob ntawm no.

Yam tshuaj mob ntshav qab zib hom 2 nyob ntawm no.

Txhua cov tshuaj siv hauv endocrinology nyob ntawm no.

Koj tuaj yeem nug ib lo lus nug lossis tawm kev rov tshuaj xyuas txog cov tshuaj (thov tsis txhob hnov ​​qab qhia lub npe ntawm cov tshuaj hauv cov ntawv sau) ntawm no.

Nruab Nrab Nres Kev Npaj Tos Txais Neeg Genetic Engineering Insulin (Human Insulin, ATX Code (ATC) A10AC01):

Cov qauv twg yog qhov zoo dua?

Pharmacological kev txiav txim

Vozulim 30/70 yog ib nrab-ntev tib neeg txoj kev siv tshuaj insulin. Cov tshuaj muaj pes tsawg leeg xws li soluble insulin (30%) thiab insulin-isophan (70%).

Nws cuam tshuam nrog ib qho kev tshwj xeeb ntawm sab cytoplasmic membrane ntawm cov hlwb thiab tsim cov txheej txheem insulin-receptor complex uas txhawb cov txheej txheem intracellular, suav nrog

synthesis ntawm tus lej ntawm cov enzym tseem ceeb (hexokinase, pyruvate kinase, glycogen synthase, thiab lwm yam).

Txo cov ntshav qabzib yog tshwm sim los ntawm kev nce ntxiv hauv nws txoj kev thauj mus los hauv lub cev, qhov ntau dua nqus thiab assimilation ntawm cov ntaub so ntswg, txhawb kev lipogenesis, glycogenogenesis, txo tus nqi ntawm cov piam thaj los ntawm lub siab, thiab lwm yam.

Lub sijhawm ntawm cov kev ua ntawm insulin npaj feem ntau vim yog tus nqi ntawm kev nqus, uas nyob ntawm ntau yam (piv txwv li, ntawm koob tshuaj, txoj kev thiab qhov chaw ntawm cov thawj coj), thiab yog li cov ntaub ntawv ntawm kev ua ntawm insulin yog raug rau qhov txawv txav, ob leeg hauv cov neeg sib txawv thiab tib tus neeg.

Qhov pib ntawm kev ua tom qab subcutaneous kev tswj hwm yog tom qab 30 feeb, cov nyhuv siab tshaj plaws yog tom qab 2-8 teev, lub sijhawm ua haujlwm tau ntev txog 24 teev.

Kev noj tshuaj ntxiv

Cov tshuaj yog npaj rau subcutaneous thawj coj. Cov koob tshuaj thiab lub sijhawm ntawm kev tswj hwm tshuaj raug txiav txim los ntawm tus kws kho mob ib leeg zuj zus hauv txhua kis raws li kev saib xyuas cov ntshav qabzib. Qhov nruab nrab, cov tshuaj txhua hnub ntawm cov tshuaj yog li 0.5 mus rau 1 IU / kg lub cev qhov hnyav (nyob ntawm tus neeg qhov yam ntxwv ntawm tus neeg mob thiab qhov siab ntawm cov ntshav qab zib).

Qhov kub ntawm cov tshuaj insulin yuav tsum nyob ntawm chav sov. Cov tshuaj feem ntau yog muab tshuaj subcutaneously hauv tus ncej puab. Kev hno tuaj yeem tuaj yeem ua rau hauv pem hauv ntej sab phab ntsa plab, pob tw lossis xub pwg hauv qhov projection ntawm cov nqaij deltoid. Nws yog ib qho tsim nyog yuav tau hloov chaw txhaj tshuaj nyob rau thaj tsam anatomical kom tiv thaiv kev txhim kho ntawm lipodystrophy.

Cov neeg mob uas muaj hom 2 mob ntshav qab zib mellitus tuaj yeem muab cov tshuaj monotherapy nrog kev siv tshuaj Vozulim 30/70 (kev tswj hwm lub sijhawm luv 2 zaug hauv ib hnub), lossis kev sib txuas nrog kev kho mob nrog qhov ncauj tshuaj hypoglycemic. Siv daim cartridge nrog rab mem kua xwb.

Sab sij huam

Vim muaj cov ntxim rau cov metabolism hauv carbohydrate: hypoglycemic tej yam kev mob (pallor ntawm daim tawv nqaij, nce tawm hws, palpitations, tshee tshee, tshaib plab, ntxhov siab, kab mob ntawm lub qhov ncauj ntawm lub qhov ntswg, mob taub hau). Kev mob ntshav qog ntshav qis tuaj yeem ua rau txhim kho kev mob hypoglycemic coma.

Kev tsis haum tshuaj: daim tawv nqaij ua pob xoos, Quincke's edema, tsis tshua muaj qhov tshwm sim - kev ua kom tsis nco qab.

Cov tshuaj tiv thaiv hauv zos: hyperemia, o thiab khaus ntawm qhov chaw txhaj tshuaj, nrog rau siv sijhawm ntev - lipodystrophy ntawm thaj chaw txhaj tshuaj.

Lwm yam: o, kev hloov pauv hloov pauv sai (feem ntau thaum pib kho).

Cev xeeb tub thiab lactation

Tsis muaj kev txwv dab tsi rau kev kho mob ntshav qab zib mellitus nrog cov tshuaj insulin thaum cev xeeb tub, txij li thaum cov tshuaj insulin tsis hla lub cev placental. Thaum npaj kev cev xeeb tub thiab thaum nws, nws yog ib qho tsim nyog yuav tsum tau ua ntu zus ntawm kev kho mob ntshav qab zib. Qhov kev xav tau rau insulin feem ntau poob qis hauv thawj peb lub hlis thaum cev xeeb tub thiab maj mam nce ntxiv hauv qib thib ob thiab thib peb.

Thaum lub sijhawm thiab yug tom qab yug, insulin yuav tsum poob ntau. Tsis ntev tom qab yug los, xav tau cov tshuaj insulin sai sai rau qib uas yog ua ntej cev xeeb tub.

Tsis muaj kev txwv rau kev kho mob ntshav qab zib mellitus nrog tshuaj insulin thaum pub niam mis.

Txawm li cas los xij, nws yuav tsim nyog los txo cov koob tshuaj insulin, yog li ntawd, kev saib xyuas ceev faj rau ntau lub hlis yog qhov tsim nyog kom txog thaum xav tau cov tshuaj insulin.

Cov lus qhia tshwj xeeb

Tawm tsam tom qab ntawm cov tshuaj insulin, kev tshuaj xyuas cov ntshav qabzib hauv siab yog qhov tsim nyog.

Qhov ua rau cov ntshav qog ntshav ua ke ntau tshaj ntawm kev siv tshuaj insulin tuaj yeem yog: hloov tshuaj, hla zaub mov noj, ntuav, raws plab, ua kom lub cev qoj ib ce, cov kab mob uas txo qis qhov xav tau ntawm insulin (kev mob siab rau lub siab thiab lub raum kev ua haujlwm, kev ua haujlwm ntawm adrenal cortex, pituitary lossis thyroid caj pas), hloov chaw txhaj tshuaj, ntxiv rau kev cuam tshuam nrog rau lwm cov tshuaj.

Kev noj tshuaj tsis yog lossis cuam tshuam rau hauv cov tshuaj insulin, tshwj xeeb tshaj yog nyob rau cov neeg mob ntshav qab zib hom 1, tuaj yeem ua rau mob hyperglycemia. Feem ntau, thawj cov tsos mob ntawm hyperglycemia pib maj mam dhau ob peb teev lossis hnub.

Cov no suav nrog kev nqhis dej, ntxiv tso zis, xeev ntuav, ntuav, kiv taub hau, liab thiab ntawm daim tawv nqaij, qhov ncauj qhuav, tsis qab los, tsis hnov ​​tsw ntawm Acetone hauv cov pa ua pa.

Yog tias tsis kho, hyperglycemia hauv ntshav qab zib hom 1 tuaj yeem ua rau muaj kev tiv thaiv cov mob ntshav qab zib ketoacidosis.

Cov koob tshuaj insulin yuav tsum raug kho kho mob thaum muaj mob qog ua haujlwm tsis txaus, Adzison's disease, hypopituitarism, kev ua haujlwm siab thiab lub raum thiab ntshav qab zib mellitus hauv cov neeg muaj hnub nyoog 65 xyoos.

Kev kho ntawm cov koob tshuaj insulin kuj tseem xav tau yog tias tus neeg mob nce ntxiv ntawm kev siv dag zog lossis hloov lub cev ib txwm noj. Cov kab mob sib xyaw tshwj xeeb, tshwj xeeb tshaj yog kis mob thiab cov kab mob nrog kub taub hau, nce ntxiv qhov xav tau ntawm insulin.

Kev hloov pauv ntawm ib hom tshuaj insulin mus rau lwm qhov yuav tsum tau ua nyob rau hauv kev tswj hwm qhov kev tswj hwm ntawm cov piam thaj hauv cov ntshav.

Cov tshuaj txo cov cawv rau lub txim.

Vim tias muaj qhov ua rau nag lossis daus hauv qee qhov ntsuas, kev siv yeeb tshuaj hauv cov tshuaj insulin tsis pom zoo.

Koj tuaj yeem siv tsis tau cov tshuaj yog tias, tom qab tshee, qhov kev ncua ntxiv tsis tig dawb lossis tusyees turbid.

Cuam tshuam rau lub peev xwm los tsav tsheb thiab tswj cov tswv yim. Vim muaj lub hom phiaj tseem ceeb ntawm insulin, hloov nws hom lossis nyob rau ntawm qhov muaj teeb meem lub cev lossis lub hlwb tseem ceeb, nws muaj peev xwm los txo lub peev xwm tsav lub tsheb lossis tswj ntau cov txheej txheem, nrog rau koom nrog rau lwm yam kev phom sij uas xav tau nce kev saib xyuas thiab ceev ntawm kev puas siab puas ntsws thiab lub cev.

Yeeb tshuaj sib cuam tshuam

Cov tshuaj tsis sib haum nrog kev daws teeb meem ntawm lwm cov tshuaj. Muaj ntau tus yeeb tshuaj uas cuam tshuam rau kev xav tau cov tshuaj insulin.

Cov nyhuv hypoglycemic ntawm insulin yog txhim kho los ntawm cov tsis muaj kev xaiv beta-blockers, quinidine, quinine, chloroquinine, monoamine oxidase inhibitors, angiotensin-hloov mus rau enzyme inhibitors, carbonic anhydrase inhibitors, octreotide, bromocriptynefin cyclofenolidenefenolides, troltrogen lithium npaj, npaj muaj ethanol.

Cov nyhuv hypoglycemic ntawm insulin yog attenuated los ntawm glucagon, somatropin, estrogens, tshuaj tiv thaiv qhov ncauj, glucocorticosteroids, iodine-muaj cov thyroid cov tshuaj hormones, thiazide diuretics, tshuaj loog, kho mob heparin, tricyclic antidepressants, sympathomimetics, daninolamine, blockin-receptor tshuaj, kab mob, tshuaj tiv thaiv kab mob, tshuaj tiv thaiv kab mob, tshuaj tiv thaiv kab mob, tshuaj tiv thaiv kab mob, tshuaj tiv thaiv kab mob, kab mob tshuaj calcium channels, diazoxide, morphine, phenytoin, nicotine.

Reserpine, salicylates tuaj yeem txhim kho ob qho tib si thiab ua kom tsis muaj zog hypoglycemic ntawm insulin.

Cov lus thiab cov xwm txheej ntawm kev cia

Nyob rau hauv qhov chaw tsaus ntawm qhov kub ntawm 2 ° C rau 8 ° C. Tsis khov. Khaws tsis ncav cuag ntawm cov menyuam yaus. Ib qho tshuaj uas siv hauv yuav tsum khaws cia ntawm qhov kub txog 15-25 ° C rau tsis pub ntau tshaj 6 lub lis piam.

Hnub tas sij hawm. 2 xyoos Tsis txhob siv tom qab hnub tas sij hawm luam tawm ntawm pob.

Vozulim: cov lus qhia rau kev siv, nqe, xyuas thiab analogues

Cov tshuaj yog kws kho rau kev txhim kho kev tiv thaiv rau hypoglycemic qhov ncauj tshuaj. Cov lus qhia rau kev siv yog qhov tsim nyog kom pom tseeb tus neeg mob kom paub meej nrog cov kev ua thiab cov yam ntxwv ntawm cov tshuaj "Vozulim".

Muab thiab kev coj:

Cov tshuaj yog npaj rau subcutaneous thawj coj. Cov koob tshuaj thiab lub sijhawm ntawm kev tswj hwm ntawm cov tshuaj yog txiav txim los ntawm tus kws kho mob tshwj xeeb hauv txhua kis, raws li cov concentration ntawm cov piam thaj hauv cov ntshav. Qhov nruab nrab, cov tshuaj txhua hnub ntawm cov tshuaj yog li 0.5 mus rau 1 IU / kg lub cev qhov hnyav (nyob ntawm tus neeg qhov yam ntxwv ntawm tus neeg mob thiab qhov siab ntawm cov ntshav qab zib).

Qhov kub ntawm cov tshuaj insulin yuav tsum nyob ntawm chav sov.

Cov tshuaj feem ntau yog muab tshuaj subcutaneously hauv tus ncej puab. Kev hno tuaj yeem tuaj yeem ua rau hauv pem hauv ntej sab phab ntsa plab, pob tw lossis xub pwg hauv qhov projection ntawm cov nqaij deltoid.

Nws yog ib qho tsim nyog yuav tau hloov chaw txhaj tshuaj nyob rau thaj tsam anatomical kom tiv thaiv kev txhim kho ntawm lipodystrophy.

Vozulim-N tuaj yeem muab rau ib leeg lossis ib leeg ua ke nrog luv luv ua yeeb yam insulin (Vozulim-P).

Siv daim cartridge nrog rab mem kua xwb.

Daim Ntawv Thov Nta:

Siv thaum cev xeeb tub thiab lactation. Tsis muaj kev txwv dab tsi rau kev kho mob ntshav qab zib mellitus nrog cov tshuaj insulin thaum cev xeeb tub, txij li thaum cov tshuaj insulin tsis hla lub cev placental. Thaum npaj kev cev xeeb tub thiab thaum nws, nws yog ib qho tsim nyog yuav tsum tau ua ntu zus ntawm kev kho mob ntshav qab zib. Qhov kev xav tau rau insulin feem ntau poob qis hauv thawj peb lub hlis thaum cev xeeb tub thiab maj mam nce ntxiv hauv qib thib ob thiab thib peb.

Thaum lub sijhawm thiab yug tom qab yug, insulin yuav tsum poob ntau. Tsis ntev tom qab yug los, xav tau cov tshuaj insulin sai sai rau qib uas yog ua ntej cev xeeb tub. Tsis muaj kev txwv rau kev kho mob ntshav qab zib mellitus nrog tshuaj insulin thaum pub niam mis. Txawm li cas los xij, nws yuav tsim nyog los txo cov koob tshuaj insulin, yog li ntawd, kev saib xyuas ceev faj rau ntau lub hlis yog qhov tsim nyog kom txog thaum xav tau cov tshuaj insulin.

Tawm tsam tom qab ntawm cov tshuaj insulin, kev tshuaj xyuas cov ntshav qabzib hauv siab yog qhov tsim nyog.

Qhov ua rau cov ntshav qog ntshav ua ke ntau tshaj ntawm kev siv tshuaj insulin tuaj yeem yog: hloov tshuaj, hla zaub mov noj, ntuav, raws plab, ua kom lub cev qoj ib ce, cov kab mob uas txo qis qhov xav tau ntawm insulin (kev mob siab rau lub siab thiab lub raum kev ua haujlwm, kev ua haujlwm ntawm adrenal cortex, pituitary lossis thyroid caj pas), hloov chaw txhaj tshuaj, ntxiv rau kev cuam tshuam nrog rau lwm cov tshuaj.

Kev noj tshuaj tsis yog lossis cuam tshuam rau hauv cov tshuaj insulin, tshwj xeeb tshaj yog nyob rau cov neeg mob ntshav qab zib hom 1, tuaj yeem ua rau mob hyperglycemia. Feem ntau, thawj cov tsos mob ntawm hyperglycemia pib maj mam dhau ob peb teev lossis hnub. Cov no suav nrog kev nqhis dej, ntxiv tso zis, xeev ntuav, ntuav, kiv taub hau, liab thiab ntawm daim tawv nqaij, qhov ncauj qhuav, tsis qab los, tsis hnov ​​tsw ntawm Acetone hauv cov pa ua pa. Yog tias tsis kho, hyperglycemia hauv ntshav qab zib hom 1 tuaj yeem ua rau muaj kev tiv thaiv cov mob ntshav qab zib ketoacidosis.

Cov koob tshuaj insulin yuav tsum raug kho rau kev ua haujlwm ntawm cov thyroid tsis zoo, Addison's disease, hypopituitarism, ua rau lub siab thiab lub raum tsis ua haujlwm thiab mob ntshav qab zib hauv cov neeg muaj hnub nyoog 65 xyoos.

Kev kho ntawm cov koob tshuaj insulin kuj tseem xav tau yog tias tus neeg mob nce ntxiv ntawm kev siv dag zog lossis hloov lub cev ib txwm noj.

Cov kab mob sib xyaw tshwj xeeb, tshwj xeeb tshaj yog kis mob thiab cov kab mob nrog kub taub hau, nce ntxiv qhov xav tau ntawm insulin.

Kev hloov pauv ntawm ib hom tshuaj insulin mus rau lwm qhov yuav tsum tau ua nyob rau hauv kev tswj hwm qhov kev tswj hwm ntawm cov piam thaj hauv cov ntshav.

Cov tshuaj txo cov cawv rau lub txim.

Vim tias muaj qhov ua rau nag lossis daus hauv qee qhov ntsuas, kev siv yeeb tshuaj hauv cov tshuaj insulin tsis pom zoo.

Koj tuaj yeem siv tsis tau cov tshuaj yog tias, tom qab tshee, qhov kev ncua ntxiv tsis tig dawb lossis tusyees turbid.

Cuam tshuam rau kev muaj peev xwm tsav tsheb thiab tswj cov tshuab. Hauv kev sib txuas nrog lub hom phiaj tseem ceeb ntawm insulin, kev hloov pauv ntawm nws hom lossis nyob ntawm qhov tseem ceeb ntawm lub cev lossis lub hlwb kev ntxhov siab, nws muaj peev xwm txo qis kev muaj peev xwm tsav lub tsheb lossis tswj ntau cov txheej txheem, nrog rau koom nrog rau lwm yam dej num txaus ntshai uas xav tau nce siab thiab ceev ntawm lub hlwb thiab lub cev kev xav.

Cov Tshuaj Pharmacokinetics

Nrog kev nqus niaj hnub, insulin mus txog qhov siab tshaj plaws ntshav plasma tom qab subcutaneous kev tswj hwm tom qab 2-18 teev. Hauv qhov no, tsis muaj kev cuam tshuam dab tsi rau cov ntshav plasma protein. Cov tshuaj tsis nkag rau hauv lub tsho me nyuam thiab mus rau niam mis.

Insulinase, protein isomerase lossis insulin protease pab txhawb nqa tib neeg cov tshuaj insulin, cov molecule uas muaj ntau qhov chaw ntawm hydrolysis. Hauv qhov xwm txheej no, cov metabolites uas tau tsim hauv tus txheej txheem tsis yog kev ua haujlwm.

Txij li 30 txog 80% ntawm cov tshuaj tso tawm los ntawm lub raum. Ib nrab-lub neej yog 5-10 teev thiab nyob ntawm tus nqi ntawm kev nqus ntawm cov rog subcutaneous.

Cov lus qhia rau siv (qauv thiab ntau npaum li cas)

"Vozulim" yog npaj rau kev qhia rau cov rog subcutaneous. Tsuas noj thiab lub sijhawm siv yog txiav txim los ntawm tus kws kho mob mus kawm nyob ntawm qhov ntsuas ntawm cov piam thaj hauv cov ntshav. Feem ntau, cov qauv txhua hnub nws txawv ntawm 0.5 mus rau 1 IU / kg raws tus neeg qhov yam ntxwv ntawm tus neeg mob.

Lub ntsuas kub ntawm qhov tso tawm qhia yuav tsum yog chav kub. Qhov chaw txheem txheem ntawm kev tswj hwm yog subcutaneous rog txheej ntawm ncej puab. Kev txhaj tshuaj rau hauv thaj av ntawm cov nqaij deltoid, sab xub ntiag phab ntsa thiab pob tw tau txais kev tso cai.

TSEEM CEEB Nws yog ib qho yuav tsum tau muab hloov chaw txhaj tshuaj kom tsis txhob muaj lipodystrophy.

Cov neeg mob uas tau los ntawm hom 2 mob ntshav qab zib mellitus tuaj yeem kho nrog Vozulim ua ke nrog lwm cov tshuaj hypoglycemic (siv hauv qhov ncauj), nrog rau kev kho mob monotherapy.

Let’s Pole Royal

Ib qhov tsis tseem ceeb hauv lub neej ntawm txhua tus mob ntshav qab zib yog kua cwj mem rau insulin. Qhov kev tsim no ua rau lub neej yooj yim rau ntau lab tus neeg mob thoob ntiaj teb. Tom qab txhua tus, yog tias muaj cwj mem li ntawm tes, tus neeg mob yuav tsis tas yuav tsum tau pabcuam kev pabcuam ntawm cov kws saib mob kom thiaj li tau txais qhov tsim nyog ntawm cov tshuaj insulin.

Qhov dhia tsawg tshaj plaws hauv qab zib tuaj yeem ua rau muaj kev phom sij, yog li kev yuav cov tshuaj txhaj yog thawj kauj ruam mus tas lub neej.

Phiv los sis:

Vim muaj cov txiaj ntsig ntawm cov metabolism hauv cov metabolism: kev ua kom lub ntsej muag hypoglycemic (pallor ntawm daim tawv nqaij, nce tawm hws, palpitations, tshee tshee, tshaib plab, ntxhov siab, kab mob plab ntawm lub qhov ncauj ntawm qhov mob, mob taub hau). Kev mob ntshav qog ntshav qis tuaj yeem ua rau txhim kho kev mob hypoglycemic coma.

Kev tsis haum tshuaj: ua pob khaus rau ntawm daim tawv nqaij, Quincke's edema, tsis tshua muaj tshwm sim - anaphylactic ceeb.

Cov tshuaj tiv thaiv hauv zos: hyperemia, o thiab khaus ntawm qhov chaw txhaj tshuaj, nrog rau siv sijhawm ntev - lipodystrophy ntawm thaj chaw txhaj tshuaj.

Lwm tus - edema, hloov pauv siv tsis raug (feem ntau thaum pib kho).

Kev cuam tshuam nrog lwm cov tshuaj:

Cov tshuaj tsis sib haum nrog kev daws teeb meem ntawm lwm cov tshuaj.

Muaj ntau tus yeeb tshuaj uas cuam tshuam rau kev xav tau cov tshuaj insulin.

Cov nyhuv hypoglycemic ntawm insulin yog txhim kho los ntawm cov tsis muaj kev xaiv beta-blockers, quinidine, quinine, chloroquinine, monoamine oxidase inhibitors, angiotensin-hloov mus rau enzyme inhibitors, carbonic anhydrase inhibitors, octreotide, bromocriptynefin cyclofenolidenefenolides, troltrogen lithium npaj, npaj muaj ethanol.

Cov nyhuv hypoglycemic ntawm insulin yog attenuated los ntawm glucagon, somatropin, estrogens, tshuaj tiv thaiv qhov ncauj, glucocorticosteroids, iodine-muaj cov thyroid hormones, thiazide diuretics, diuretics, tshuaj kho mob, tricyclic antidepressants, sympathomimetics, daninolamine, blockin-epidamine, receptor tshuaj calcium channels, diazoxide, morphine, phenytoin, nicotine.

Reserpine, salicylates tuaj yeem txhim kho ob qho tib si thiab ua kom tsis muaj zog hypoglycemic ntawm insulin.

Cia rau cov neeg mob:

Khaws rau hauv qhov chaw tsaus ntawm qhov kub ntawm +2 ° С txog +8 ° С. Tsis khov. Khaws tsis ncav cuag ntawm cov menyuam yaus. Ib qho tshuaj uas siv hauv yuav tsum khaws cia ntawm qhov kub txog 15-25 ° C rau tsis pub ntau tshaj 6 lub lis piam. Txee lub neej yog 2 xyoos. Tsis txhob siv tom qab hnub tas sij hawm luam tawm ntawm pob.

Cov sijhawm so:

Ncua rau lub subcutaneous tswj ntawm 100 IU / ml.

3 ml hauv nruab nrab daim iav cartridges (hom I). Ib daim ntawv lo yog txuas rau daim cartridge. 1 lossis 5 daim cartridges raug muab tso rau hauv lub hlwv ntawm PVC / txhuas ntawv ci.

10 ml hauv vials ntawm cov iav tsis muaj xim nruab nrab, kaw nrog roj hmab nres thiab txhav nrog txhuas hau nrog lub hau yas kev ruaj ntseg.

Txhua lub raj mis lossis txhua lub hlwv nrog lub thawv cartridge 1 lossis tus lej 5 tso rau hauv lub thawv ntawv thawv nrog cov lus qhia rau kev siv.

Cov lus qhia rau kev siv Protafan NM tau muab rau tus neeg mob

Vials nrog cov tshuaj Protafan NM tuaj yeem siv tsuas yog ua ke nrog cov kua dej insulin, ntawm qhov ntsuas qhov ntsuas, uas tso cai ntsuas ntsuas qhov ntsuas hauv cov chav ua haujlwm.

Vials nrog cov tshuaj Protafan NM yog npaj rau kev siv tus kheej nkaus xwb.

Ua ntej pib siv lub raj mis tshiab ntawm Protafan HM, nws raug nquahu kom cov tshuaj kom sov so rau chav sov ua ntej nplawm.

Ua ntej siv cov tshuaj Protafan NM nws yog qhov tsim nyog:

1. Kuaj cov ntawv ntim kom paub tseeb tias hom roj ntsha insulin raug xaiv.
2. Txhawm rau tshem tawm cov roj hmab nres nrog cov pas nrig.

Tshuaj Protafan NM tsis tuaj yeem siv nyob rau hauv cov teebmeem hauv qab no:

1. Tsis txhob siv cov tshuaj hauv cov tshuaj insulin.
2. Nws yog qhov tsim nyog rau cov neeg mob piav qhia tias yog tias lub cap tshiab uas nyuam qhuav tau txais los ntawm lub tsev muag tshuaj tsis muaj lub hau tiv thaiv lossis nws tsis zaum nruj, qhov tshuaj insulin no yuav tsum rov qab mus rau lub tsev muag tshuaj.
3. Yog tias cov tshuaj insulin tsis khaws cia kom raug, lossis yog nws khov.
4. Yog tias thaum tov cov ntsiab lus ntawm lub thauv raws li cov lus qhia rau kev siv, cov tshuaj insulin tsis dhau los ua uniformly dawb thiab huab.

Yog tias tus neeg mob siv tsuas yog ib hom tshuaj insulin:

1. Tam sim ntawv ua ntej hu, yob lub raj mis ntawm koj xib teg kom txog thaum cov tshuaj insulin dawb thiab pos huab. Resuspension yog kev yooj yim yog hais tias cov tshuaj muaj chav sov.
2. Kos cua rau hauv cov tub txhaj tshuaj nyob rau hauv qhov uas yuav tsum tau txhaj rau qhov xav tau ntawm cov tshuaj insulin.
3. Nkag mus rau hauv huab cua mus rau hauv lub vias ntawm cov tshuaj insulin: rau qhov no, cov roj hmab nres tso rau ntawm xuas nrig ntaus thiab koob tau nias.
4. Tig lub taub hau dej haus kom nres.
5. Ntaus cov tshuaj uas xav tau ntawm cov tshuaj insulin rau hauv cov phwj.
6. Tshem tawm rab koob ntawm lub vial.
7. Tshem tawm cov cua ntawm lub koob txhaj tshuaj.
8. Kuaj qhov tseeb.
9. Hno tam sim.

Yog tias tus neeg mob xav tau sib xyaw Protafan NM nrog cov tshuaj insulin luv luv:

1. Dov lub raj mis nrog Protafan NM (“muaj huab”) nyob nruab nrab ntawm koj xib teg kom txog thaum cov kua tshuaj ci ci kom dawb thiab huab. Resuspension yog kev yooj yim yog hais tias cov tshuaj muaj chav sov.
2. Tso cov huab cua rau hauv rab koob txhaj tshuaj uas yog siv cov tshuaj Protafan NM (“insulin” huab). Tshaj tawm huab cua rau hauv vial ntawm huab insulin thiab tshem tawm rab koob ntawm lub vial.
3. Kos cua rau hauv lub qhov ntswg hauv qhov ntau npaum li cas ntawm cov koob tshuaj insulin luv luv ("pob tshab"). Ntxig huab cua rau hauv lub raj mis nrog cov tshuaj no. Tig lub taub hau dej haus kom nres.
4. Hu rau qhov koob xav tau ntawm kev ua yeeb yam luv luv ("meej"). Tshem tawm cov koob tawm thiab tshem tawm cov cua ntawm lub koob txhaj tshuaj. Kuaj qhov tseeb.
5. Muab rab koob tso rau hauv lub raj mis nrog Protafan HM ("insulin" "insulin") thiab muab lub taub mis tso nrog lub taub hau ntxeev tiaj.
6. Hu lub koob xav tau ntawm Protafan NM. Tshem tawm rab koob ntawm lub vial. Tshem tawm cov cua hauv lub koob txhaj tshuaj thiab xyuas seb qhov koob tshuaj muaj tseeb li cas.
7. Ncaws cov tshuaj insulin luv thiab ntev ua rau koj tau txhaj tam sim ntawd.

Txhua zaus yuav tsum ua luv luv thiab ntev ua yeeb yam insulins nyob rau hauv kev ua ntu zus li tau piav saum toj no.

Qhia tus neeg mob kom tswj cov tshuaj insulin hauv cov xwm txheej ib yam li tau piav saum toj no.

1. Nrog rau ob tug ntiv tes, sau cov kab ntawm daim tawv nqaij, ntxig rab koob rau hauv lub hauv paus ntawm quav ntawm kaum ntawm 45 degrees, thiab txhaj tshuaj insulin hauv qab daim tawv nqaij.
2. Tom qab txhaj, koob yuav tsum nyob twj ywm hauv qab daim tawv nqaij tsawg kawg 6 vib nas this, txhawm rau xyuas kom meej tias cov insulin nkag.

Vozulim-N (Vozulim-N) WOCKHARDT (Is Nrias teb) raug tshem tawm rau kev tswj hwm subcutaneous

Tus neeg sawv cev hypoglycemic, nruab nrab insulin tau los ntawm kev tsim hluav taws xob, yog zoo tib yam rau tib neeg cov insulin.

Sib cuam tshuam nrog ib qhov tshwj xeeb receptor rau ntawm sab nraud ntawm lub hlwb, tsim cov txheej txheem insulin. Los ntawm nce cov synthesis ntawm cAMP (hauv cov roj ntsha thiab lub siab hlwb) lossis nkag ncaj qha rau hauv lub cell (leeg), insulin receptor complex stimulates intracellular processes, suav nrog synthesis ntawm cov lej ntawm cov enzymes tseem ceeb (suav nrog rau hexokinase, pyruvate kinase, glycogen synthetase).

Kev txo qis hauv cov concentration ntawm cov piam thaj hauv cov ntshav yog tshwm sim los ntawm kev nce ntxiv hauv nws txoj kev thauj mus los, kev nqus thiab pov tseg ntau los ntawm cov nqaij mos, ua kom muaj zog ntawm lipogenesis, glycogenogenesis, synthesis protein, thiab txo tus nqi ntawm cov piam thaj los ntawm lub siab (txo qis hauv glycogen tawg).

Kev nqus thiab pib ntawm kev nqis tes ua nyob ntawm txoj kev ntawm kev coj (sc lossis intramuscularly), qhov chaw nyob (plab, ncej puab, pob tw) thiab qhov ntim ntawm kev txhaj tshuaj, cov concentration ntawm insulin hauv tshuaj. Nws muab faib ua qhov tsis sib luag hauv daim ntaub, tsis nkag mus rau hauv qhov chaw nres thiab nkag mus rau niam mis. Nws yog rhuav tshem los ntawm insulinase, feem ntau yog nyob hauv daim siab thiab lub raum. Nws yog tawm los ntawm lub raum (30-80%).

Hom 2 mob ntshav qab zib mellitus Hom 2 mob ntshav qab zib mellitus: theem ntawm kev tawm tsam cov tshuaj tiv thaiv kab mob hauv lub qhov ncauj, tiv taus ib feem los ntawm cov tshuaj no (thaum kho sib txuam), cov kab mob sib kis, hom 2 mob ntshav qab zib mellitus hauv cov poj niam cev xeeb tub.

Vim muaj cov txiaj ntsig ntawm cov metabolism hauv cov metabolism: cov ntshav lub qog ua ntshav (pallor ntawm daim tawv nqaij, nce tawm hws, palpitations, tshee tshee, tshaib plab, ntxhov siab, teeb meem hauv lub qhov ncauj, mob taub hau). Kev mob ntshav qog ntshav qis tuaj yeem ua rau txhim kho kev mob hypoglycemic coma.

Kev ua xua: tsis tshua muaj - pob khaus rau ntawm daim tawv nqaij, Quincke's edema, tsis tshua muaj tshwm sim - ceeb thawj anaphylactic.

Lwm yam: kab mob edema, qhov hloov pauv sai sai (feem ntau thaum pib kho).

Cov tshuaj tiv thaiv hauv zos: hyperemia, o thiab khaus ntawm qhov chaw txhaj tshuaj, nrog rau siv sijhawm ntev - lipodystrophy ntawm thaj chaw txhaj tshuaj.

Nkag s / c, 1-2 zaug / hnub, 30-45 feeb ua ntej noj tshais. Qhov chaw txhaj tshuaj yuav tsum tau hloov txhua zaus. Hauv qhov xwm txheej tshwj xeeb, a / m cov lus qhia yog ua tau.

Hauv / hauv kev qhia ntawm cov tshuaj insulin ntawm lub sijhawm nruab nrab tsis tso cai.

Cov koob tshuaj tau teeb tsa ib tus zuj zus, nyob ntawm cov ntsiab lus ntawm cov piam thaj hauv cov ntshav thiab zis, cov yam ntxwv ntawm chav kawm ntawm tus kabmob.

Cov tsos mob: kev txhim kho hypoglycemia (tawm hws txias, tawm hws, tshee tshee, tshaib plab, ntxhov siab, chim siab, pallor, mob taub hau, tsaug zog, tsis muaj zog, hais lus thiab pom kev tsis pom kev zoo, kev nyuaj siab).Kev mob ntshav khov ntau heev tuaj yeem ua rau lub hlwb ua haujlwm ib ntus lossis tas mus li, tsis nco qab, thiab tuag.

Kev Kho Mob: cov kua qab zib lossis kua nplaum hauv sab hauv (yog tias tus neeg mob nco qab zoo), s / c, i / m lossis iv - glucagon lossis iv - qabzib.

Ncua rau sc thawj coj.

10 ml - iav fwj (1) - thawv ntawv thawv.
3 ml - cartridges (1) - hlwv pob (1) - pob khoom los ntawm cardboard.

Cov nyhuv hypoglycemic yog txhim kho los ntawm sulfonamides (suav nrog cov tshuaj tiv thaiv hypoglycemic qhov ncauj, sulfanilamides), MAO inhibitors (suav nrog furazolidone, procarbazine, selegiline), carbonic anhydrase inhibitors, ACE inhibitors, NSAIDs (suav nrog

salicylates), anabolic steroids (suav nrog

stanozolol, oxandrolone, methandrostenolone), androgens, bromocriptine, tetracyclines, clofibrate, ketoconazole, mebendazole, theophylline, cyclophosphamide, fenfluramine, lithium npaj, pyridoxine, quinidine, quinine, chloroquinine.

Glucagon, somatropin, GCS, tshuaj tiv thaiv muaj qhov ncauj, estrogens, thiazide thiab "voj" diuretics, calcium channel blockers, cov thyroid hormones, heparin, sulfin pyrazone, sympathomimetics, danazole, tricyclic antidepressants, calcium chloride, moron, txo cov nyhuv hypoglycemic. nicotine, phenytoin, epinephrine, histamine H1 receptor blockers.

Beta-blockers, reserpine, octreotide, pentamidine tuaj yeem ob leeg txhim kho thiab txo cov nyhuv hypoglycemic ntawm insulin.

Cov tshuaj tsis sib haum nrog kev daws thiab lwm yam tshuaj.

Nws yog ib qho tsim nyog yuav tsum hloov chaw txhaj tshuaj nyob rau thaj tsam anatomical thiaj li tiv thaiv kev txhim kho ntawm lipodystrophy.

Tawm tsam keeb kwm yav dhau los ntawm kev kho mob insulin, kev tshuaj xyuas cov ntshav qabzib ntau yog tsim nyog.

Cov ua rau cov ntshav qog ntshav, ntxiv rau kev noj tshuaj insulin ntau dhau, tuaj yeem yog: hloov tshuaj, hla zaub mov, ntuav, raws plab, ua kom lub cev qoj ib ce, cov kab mob uas txo qis qhov xav tau ntawm insulin (kev mob siab rau lub siab thiab lub raum kev ua haujlwm, kev ua haujlwm ntawm adrenal cortex, pituitary lossis thyroid caj pas), hloov chaw txhaj tshuaj, nrog rau kev sib cuam tshuam nrog lwm yam tshuaj.

Kev noj tshuaj tsis zoo los yog cuam tshuam hauv kev tswj hwm insulin, tshwj xeeb tshaj yog nyob rau cov neeg mob ntshav qab zib hom 1, tuaj yeem ua rau mob hyperglycemia. Feem ntau, thawj cov tsos mob ntawm hyperglycemia pib maj mam dhau ob peb teev lossis hnub.

Cov no suav nrog kev nqhis dej, ntxiv tso zis, xeev ntuav, ntuav, kiv taub hau, liab thiab ntawm daim tawv nqaij, qhov ncauj qhuav, tsis qab los, tsis hnov ​​tsw ntawm Acetone hauv cov pa ua pa.

Yog tias tsis kho, hyperglycemia hauv ntshav qab zib hom 1 tuaj yeem ua rau muaj kev tiv thaiv cov mob ntshav qab zib ketoacidosis.

Cov koob tshuaj insulin yuav tsum tau hloov kho thaum muaj mob qog ua haujlwm, Addison's disease, hypopituitarism, ua rau lub siab thiab lub raum ua haujlwm thiab mob ntshav qab zib mellitus hauv cov neeg mob hnub nyoog 65 xyoos. Hloov cov koob tshuaj ntawm cov tshuaj insulin kuj tseem xav tau yog tias tus neeg mob ua kom lub cev txav ntau ntxiv lossis hloov cov zaub mov ib txwm muaj.

Cov kab mob sib xyaw tshwj xeeb, tshwj xeeb tshaj yog kis mob thiab cov kab mob nrog kub taub hau, nce ntxiv qhov xav tau ntawm insulin.

Kev hloov pauv ntawm ib hom tshuaj insulin mus rau lwm qhov yuav tsum tau ua nyob ntawm kev tswjhwm ntawm cov ntshav nyob rau qib.

Cov tshuaj txo qis cawv rau cov neeg haus cawv.

Hauv kev sib txuas nrog lub hom phiaj tseem ceeb ntawm insulin, qhov kev hloov pauv ntawm nws hom lossis nyob ntawm qhov tseem ceeb ntawm lub cev lossis lub hlwb kev ntxhov siab, nws muaj peev xwm txo qis kev muaj peev xwm tsav lub tsheb lossis tswj ntau cov txheej txheem, nrog rau koom nrog lwm yam kev phom sij uas xav tau kev nce siab thiab ceev ntawm lub hlwb thiab lub cev kev xav.

Thaum cev xeeb tub, nws yog ib qho tsim nyog yuav tsum coj mus rau hauv qhov kev txo qis hauv qhov xav tau ntawm cov tshuaj insulin hauv thawj peb lub hlis lossis nce ntxiv ntawm zaum ob thiab thib peb. Thaum lub sijhawm thiab yug tom qab yug, insulin yuav tsum poob ntau.

Thaum lub sijhawm lactation, kev soj ntsuam txhua hnub yog xav tau rau ntau lub hlis (txog thaum qhov xav tau cov tshuaj insulin yuav ruaj khov).

Qhov kev xav tau rau insulin tuaj yeem sib txawv nrog kab mob siab.

Qhov kev xav tau rau insulin tuaj yeem sib txawv nrog kab mob hauv lub raum. Kev txhaj tshuaj insulin yuav tsum nyob rau hauv lub raum ua kom tsis ua hauj lwm.

Vozulim-N (Vozulim-N) WOCKHARDT (Is Nrias teb) raug tshem tawm rau kev tswj hwm subcutaneous

Vozulim-n - cov lus qhia rau kev siv hauv Yandex.Health

Tawm tsam tom qab ntawm cov tshuaj insulin, kev tshuaj xyuas cov ntshav qabzib hauv siab yog qhov tsim nyog.

Qhov ua rau cov ntshav qog ntshav ua ke ntau tshaj ntawm kev siv tshuaj insulin tuaj yeem yog: hloov tshuaj, hla zaub mov noj, ntuav, raws plab, ua kom lub cev qoj ib ce, cov kab mob uas txo qis qhov xav tau ntawm insulin (kev mob siab rau lub siab thiab lub raum kev ua haujlwm, kev ua haujlwm ntawm adrenal cortex, pituitary lossis thyroid caj pas), hloov chaw txhaj tshuaj, ntxiv rau kev cuam tshuam nrog rau lwm cov tshuaj.

Kev noj tshuaj tsis yog lossis cuam tshuam rau hauv cov tshuaj insulin, tshwj xeeb tshaj yog nyob rau cov neeg mob ntshav qab zib hom 1, tuaj yeem ua rau mob hyperglycemia. Feem ntau thawj cov tsos mob ntawm hyperglycemia pib maj mam dhau ob peb teev lossis hnub.

Cov no suav nrog kev nqhis dej, tso zis tsis tu ncua, xeev ntuav, ntuav, kiv taub hau, liab thiab ntawm daim tawv nqaij, qhov ncauj qhuav, tsis qab los, tsis hnov ​​ntxhiab ntawm cov acetone hauv cov pa tawm.

Yog tias tsis kho, hyperglycemia hauv ntshav qab zib hom 1 tuaj yeem ua rau muaj kev tiv thaiv cov mob ntshav qab zib ketoacidosis.

Cov koob tshuaj cov tshuaj insulin yuav tsum tau kho nyob rau hauv kev txiav txim siab ntawm lub qog ua haujlwm tsis txaus, Addison's disease, hypopituitarism, ua rau lub siab thiab lub raum tsis ua haujlwm, thiab mob ntshav qab zib mellitus hauv cov neeg mob uas muaj hnub nyoog 65 xyoos.

Hauv kev pom ntawm kev pheej hmoo ntawm lub plawv mob thiab lub hlwb ntawm lub qog ntshav qab zib, cov tshuaj insulin yuav tsum tau siv nrog ceev faj hauv cov neeg mob uas mob hnyav ntawm cov hlab ntshav ntawm lub plawv thiab cov hlab ntsha txhaws.

Nrog faj seeb nyob rau hauv cov neeg mob proliferative retinopathy, tshwj xeeb tsis tau txais kev kho mob nrog photocoagulation (laser coagulation) vim muaj kev pheej hmoo ntawm amaurosis (ua tiav dig muag).

Yog tias tus neeg mob ua kom lub cev ua hauj lwm ntau ntxiv lossis hloov cov zaub mov ib txwm noj, yuav tsum tau txhaj tshuaj insulin kom haum.

Cov kab mob sib xyaw tshwj xeeb, tshwj xeeb tshaj yog kis mob thiab cov kab mob nrog kub taub hau, nce ntxiv qhov xav tau ntawm insulin.

Kev hloov chaw ntawm tus neeg mob mus rau ib hom tshiab ntawm insulin lossis kev npaj tshuaj insulin ntawm lwm qhov chaw tsim khoom yuav tsum tau ua nyob rau hauv kev saib xyuas ntawm kws kho mob.

Thaum siv cov tshuaj insulin nyob rau hauv kev sib xyaw nrog cov tshuaj ntawm thiazolidinedione pab pawg, cov neeg mob uas muaj ntshav qab zib hom 2 mob ntshav qab zib yuav muaj kev tso dej tawm, uas ua rau muaj kev pheej hmoo ntawm kev txhim kho thiab kev txhim kho mob plawv tsis ua haujlwm, tshwj xeeb tshaj yog nyob rau cov neeg mob uas muaj kab mob ntawm cov hlab plawv thiab muaj cov kev pheej hmoo rau mob ntev lub plawv tsis ua hauj lwm. Cov neeg mob uas tau txais kev kho mob zoo li no yuav tsum tau kuaj xyuas tsis tu ncua kom pom cov cim ntawm lub plawv tsis ua haujlwm. Yog tias lub plawv tsis ua haujlwm tshwm sim, txoj kev kho yuav tsum ua raws li cov qauv kev kho mob tam sim no. Hauv qhov no, nws yog ib qho tsim nyog los xav txog kev ncua lossis txo qhov txo cov thiazolidinedione.

- hom ntshav qab zib 1

- hom 2 mob ntshav qab zib mellitus: theem ntawm kev tawm tsam cov tshuaj tiv thaiv kab mob hauv lub qhov ncauj, ib feem tawm tsam cov tshuaj no (thaum kho sib txuam), cov kab mob sib kis,

- Hom Ntshav Qab Zib 2 hauv cov poj niam cev xeeb tub.

Kev Rau Txim Rau SC cov thawj coj

- nce ib tug neeg rhiab rau insulin los yog ib qho ntawm cov tshuaj ntawm cov tshuaj.

Muab thiab kev coj:

Cov tshuaj yog npaj rau sc tswj nkaus xwb. Cov koob tshuaj ntawm cov tshuaj tau txiav txim siab los ntawm tus kws kho mob tshwj xeeb hauv txhua kis, raws li kev mloog zoo ntawm cov piam thaj hauv cov ntshav.

Qhov nruab nrab, cov tshuaj txhua hnub ntawm cov tshuaj yog li 0.5 mus rau 1 IU / kg lub cev qhov hnyav (nyob ntawm tus neeg qhov yam ntxwv ntawm tus neeg mob thiab qhov siab ntawm cov ntshav qab zib).

Cov neeg laus uas tau txais ib qho insulin, suav nrog Vosulim-H, yog muaj kev pheej hmoo ntawm cov ntshav qog ntshav ntau vim tias muaj cov kab mob sib xyaw ua ke thiab kev siv ntau yam tshuaj ib zaug. Nws yuav tsim nyog los kho lub koob tshuaj insulin.

Cov neeg mob uas lub raum lub raum thiab lub cev tsis ua haujlwm yog qhov muaj feem yuav ua rau lub qog ntshav nce siab thiab xav tau cov tshuaj insulin ntau dua thiab yuav tsum tau soj ntsuam cov ntshav qabzib ntau dua.

Nruab nrab-lub sijhawm tib neeg cov kua dej tau txais siv siv thev naus laus zis DNA thev naus laus zis.

Nws cuam tshuam nrog ib qho kev tshwj xeeb ntawm sab cytoplasmic membrane ntawm cov hlwb thiab tsim cov txheej txheem insulin-receptor complex uas txhawb cov txheej txheem intracellular, suav nrog synthesis ntawm cov naj npawb ntawm cov enzymes tseem ceeb (hexokinase, pyruvate kinase, glycogen synthetase).

Cov thawj nyob hauv cov ntshav nyob rau hauv lub cev yog vim qhov nce ntxiv hauv nws txoj kev thauj mus los hauv lub cev, kev nqus thiab kev pov tseg ntau ntawm cov nqaij mos, ua kom cov lipogenesis, glycogenogenesis, thiab txo tus nqi ntawm cov piam thaj los ntawm lub siab.

Lub sijhawm ntawm cov kev ua ntawm insulin npaj feem ntau vim yog tus nqi ntawm kev nqus, uas nyob ntawm ntau yam (piv txwv li, ntawm koob tshuaj, txoj kev thiab qhov chaw ntawm cov thawj coj), thiab yog li cov ntaub ntawv ntawm kev ua ntawm insulin yog raug rau qhov txawv txav, ob leeg hauv cov neeg sib txawv thiab tib tus neeg.

Qhov nruab nrab, tom qab kev tswj hwm sc, nws pib ua tom qab 1.5 teev, qhov ua tau zoo tshaj plaws tsim tawm ntawm 4 teev thiab 12 teev, lub sijhawm ua haujlwm tau ntev txog 24 teev.

Qhov tshwm sim vim qhov tshwm sim ntawm cov metabolism hauv kev noj haus: hypoglycemic tej yam kev mob (pallor ntawm daim tawv nqaij, nce tawm hws, palpitations, tshee tshee, tshaib plab, ntxhov siab, teeb tsa ntawm lub qhov ncauj mucosa, mob taub hau, kiv taub hau, tsis pom kev zoo nkauj). Kev mob ntshav qog ntshav qis tuaj yeem ua rau txhim kho kev mob hypoglycemic coma.

Kev ua xua: ua pob khaus rau ntawm daim tawv nqaij, Quincke's edema, qhov tsis pom kev tsis nco qab.

Cov tshuaj tiv thaiv hauv zos: hyperemia, o thiab khaus ntawm qhov chaw txhaj tshuaj, nrog rau siv sijhawm ntev - lipodystrophy ntawm thaj chaw txhaj tshuaj.

Lwm yam: edema, hloov qis qis hauv qhov pom tseeb (feem ntau thaum pib kho).

Tus neeg mob yuav tsum tau qhia paub tias yog nws sau tseg kev txhim kho ntawm lub qog ntshav qab zib lossis muaj kev nco qab sai sai, nws yuav tsum qhia tus kws kho mob sai.

Yog tias muaj lwm cov kev phiv dab tsi tsis tau piav los saum no tau txheeb pom, tus neeg mob yuav tsum tau sab laj nrog kws kho mob.

Cov tshuaj yuav tsum tsis txhob siv yog tias, tom qab tshee, qhov kev ncua tsis dhau dawb thiab ib zaug huab.

Tawm tsam tom qab ntawm cov tshuaj insulin, kev tshuaj xyuas cov ntshav qabzib hauv siab yog qhov tsim nyog.

Qhov ua rau cov ntshav qog ntshav ua ke ntau tshaj ntawm kev siv tshuaj insulin tuaj yeem yog: hloov tshuaj, hla zaub mov noj, ntuav, raws plab, ua kom lub cev qoj ib ce, cov kab mob uas txo qis qhov xav tau ntawm insulin (kev mob siab rau lub siab thiab lub raum kev ua haujlwm, kev ua haujlwm ntawm adrenal cortex, pituitary lossis thyroid caj pas), hloov chaw txhaj tshuaj, ntxiv rau kev cuam tshuam nrog rau lwm cov tshuaj.

Kev noj tshuaj tsis zoo los yog cuam tshuam hauv kev tswj hwm insulin, tshwj xeeb tshaj yog nyob rau cov neeg mob ntshav qab zib hom 1, tuaj yeem ua rau mob hyperglycemia. Feem ntau thawj cov tsos mob ntawm hyperglycemia pib maj mam dhau ob peb teev lossis hnub.

Cov no suav nrog kev nqhis dej, tso zis tsis tu ncua, xeev ntuav, ntuav, kiv taub hau, liab thiab ntawm daim tawv nqaij, qhov ncauj qhuav, tsis qab los, tsis hnov ​​ntxhiab ntawm cov acetone hauv cov pa tawm.

Yog tias tsis kho, hyperglycemia hauv ntshav qab zib hom 1 tuaj yeem ua rau muaj kev tiv thaiv cov mob ntshav qab zib ketoacidosis.

Hauv kev sib txuas nrog lub hom phiaj tseem ceeb ntawm insulin, qhov kev hloov pauv ntawm nws hom, lossis nyob rau ntawm qhov tseem ceeb ntawm lub cev lossis lub hlwb kev ntxhov siab, nws muaj peev xwm txo qis kev muaj peev xwm tsav tsheb los yog ntau yam txheej txheem, nrog rau kev koom ua lwm yam uas yuav muaj kev phom sij uas xav tau nce siab thiab ceev ntawm cov tshuaj tiv thaiv ..

Muaj ntau tus yeeb tshuaj uas cuam tshuam rau kev xav tau cov tshuaj insulin.

Hypoglycemic nyhuv ntawm insulin txhim khu qhov ncauj hypoglycemic tshuaj, Mao inhibitors, ACE inhibitors, carbonic anhydrase inhibitors, xim beta-blockers, bromocriptine, octreotide, sulfonamides, anabolic steroids, tetracyclines, clofibrate, ketoconazole, mebendazole, pyridoxine, theophylline, cyclophosphamide, fenfluramine, lithium npaj npaj muaj ethanol.

Cov nyhuv hypoglycemic ntawm insulin yog attenuated los ntawm glucagon, somatropin, estrogens, tshuaj tiv thaiv qhov ncauj, corticosteroids, iodine-muaj cov thyroid hormones, thiazide diuretics, "loop" diuretics, heparin, tricyclic antidepressants, sympathomimetics, corticosteroids, iodine-muaj cov thyroid hormones, thiazide diuretics, "loop" diuretics, heparin, tricyclic antidepressants, sympathomimetics, danazole, clonidine receptors, calininsine receptors , diazoxide, morphine, phenytoin, nicotine.

Nyob rau hauv kev cuam tshuam ntawm reserpine thiab salicylates, ob qho tib si ua rau qaug zog thiab nce ntxiv hauv kev ua ntawm cov tshuaj muaj peev xwm ua tau.

Dab tsi ntawm cov koob txhaj tshuaj muaj?

Thaum muaj ntshav qab zib mellitus, cov txheej txheem metabolic maj mam tshwm sim hauv lub cev vim qhov ua haujlwm tsis zoo hauv cov hluavtaws insulin. Kev kho mob ntshav qab zib hom 1 cuam tshuam nrog kev tswj hwm ntawm kev ua haujlwm qub. Lub koob txhaj tshuaj yog tsim los tswj kev siv tshuaj sai rau hauv lub cev thaum muaj xwm txheej ceev. Muaj ntau hom kev txhaj tshuaj:

• Cov koob txhaj raws cov koob uas tshem tau. Qhov peculiarity ntawm kev ua haujlwm ntawm tus cwj mem yog tias tus neeg mob xav tau ntxig ib rab koob tshiab txhua lub sijhawm ua ntej yuav noj tshuaj thiab tswj hwm nws.
• Cov koob txhaj tshuaj uas muaj koob xav ua. Hom cuab yeej zoo li no tau qhia tias rab koob muaj lub npe hu ua "cheeb tsam tuag", uas ua rau txo qis kev phom sij.

Yuav ua li cas xaiv cov xwj xaum xaum rau kev insulin?

Txhua rab phom insulin rau cov neeg mob ntshav qab zib tau tsim los ua kom tau raws li txhua yam ntawm cov neeg mob ntshav qab zib.

Lub piston ntawm tus kov yuav tsum ua nyob rau hauv txoj kev uas nws yooj yim tshaj plaws los siv cov koob txhaj tshuaj yam tsis muaj qhov mob. Thaum muas lub insulin syringe, nws yog qhov tseem ceeb yuav tsum them sai sai rau cov nplai ntawm lub cuab yeej.

Koj yuav tsum xaiv ib rab koob xaim hluav taws nyob hauv qhov hnyav, nruab nrog lub suab nrov uas tau muab thaum txhaj cov tshuaj hormones.

Tus kws kho mob xaiv cov tshuaj ntau npaum li cas, feem ntau lawv ntaus nqi 0.5 rau cov menyuam yaus, thiab 1 koog rau cov neeg laus.

"Protafan NM Penfil".

Kev siv raug tso cai tsuas yog rau kev txhaj tshuaj subcutaneous, nws yog txwv tsis pub nkag rau qhov quav. Nws raug nquahu kom hloov chaw txhaj tshuaj txhua zaus.

Qhov kev ncua yog muab cais ua pawg pab pawg insulin nrog lub sijhawm ua haujlwm ntev. Muaj nyob hauv 5 daim cartridges. Tom qab txhua tus siv Protafan, nws yog ib qho tseem ceeb uas yuav tsum tau ua kom paub tseeb tias cov koob tau tawm ntawm rab koob txhaj tshuaj.

Txwv tsis pub, cov tshuaj yuav xau, uas yog txaus ntshai los ntawm kev hloov nws cov kev xav.

Tshuaj yaug R

Qhov kev npaj Rinsulin NPH npaj rau kev siv rov ua haujlwm. Koj tsis tuaj yeem rov ntxiv cov tshuaj yog tias nws raug rau khov. Tau txais cov khoom los ntawm synthesis, muaj lub sijhawm luv luv ntawm kev ua. Tshaj rau siv nrog RinAstra kov. Nws tsuas ua haujlwm yog tias cov tshuaj tau nce mus txog chav kub.

"Cia nqa-N Royal"

Txhawm rau tswj cov tshuaj insulin, koj xav tau Wozulim Pen Royal insulin injector. Cov tshuaj ua ke nruab nrab thiab luv lub sij hawm hluavtaws cov tshuaj insulin. Nws raug nquahu kom xyuam xim nrog rau cov neeg mob uas mob raum. Nws tuaj yeem siv thaum cev xeeb tub, cov tshuaj tsis hla tus kheej. Lub sijhawm tiv thaiv kev rau ncua yog 24 teev.

Rosinsulin

Cov ntaub ntawv rov tuaj yeem siv tus cwj mem "Rosinsulin Comfort Pen" muaj cov ntaub ntawv cov tawv tawv hnyav. Tus neeg siv tuaj yeem hloov kho qhov koob tshuaj, cov cuab yeej muaj cov log muag muag rau ib txheej ntawm cov cuab yeej.

Cov cuab yeej muaj qhov kev faib tawm meej nrog nce mus txog 60 ib pawg. Qhov tsim nyog rau cov neeg tsis pom kev zoo. Tus cwj mem ciav yog tsim los rau siv ntau nrog kev muaj peev xwm hloov lub pob txha.

Muaj txoj hauv kev hloov lub koob tsis haum. Xws li yog kev qhia ua.

BiomaticPen

Tus kov coj txawv ntawm lwm cov tuam ntxhab hauv kev xuas tes kom zoo dua nrog rab koob nyias, uas txo qhov mob tsawg kawg nkaus.

BiomatikPen yog qhov tsim nyog rau Biosulin, tuaj yeem yuav hauv khw muag khoom tshwj xeeb lossis hauv cov npe online.

Cov cuab yeej muaj lub tshuab hluav taws xob tsis zoo no feem uas qhia txog qhov ntau npaum li cas ntawm cov tshuaj. Ua ntej koj nkag mus rau "Biosulin", koj yuav tsum nyeem cov lus qhia.

HumaPen Savvio

Cov koob txhaj tshuaj "Humapen Savvio" yog npaj rau qhov ua kom xis nyob thiab tsis muaj mob ntawm cov tshuaj insulin rau cov ntshav qab zib. Qhov txawv txav tshwj xeeb yog qhov tsim qauv ntawm cov koob tshuaj txhaj tshuaj.

Cov cuab yeej siv hluav taws xob yog txhuas, tiv taus cov khoom siv los tiv thaiv kev tawg thiab khawb hauv rooj plaub. Ua kom tiav nrog ib rooj plaub tuaj hauv hnab tshos tuaj yeem ntim tau li 6 koob. Muaj ob peb xim.

Nruab nrog lub tshuab xa khoom siv thiab cov tshuab txiav txim siab koob tshuaj.

Autopen classic

Autopen Classic rov siv cov phom insulin yog sib xws nrog ntau hom tshuaj insulin, xws li Biosulin, Rosinsulin thiab lwm yam.

Cov cuab yeej Avtopen tseem tuaj yeem siv nrog txhua yam koob uas xav tau. Lub Autopen syringe cwj mem suav nrog: lub tshuab ua kom sib haum, rooj plaub muag, 3 rab koob koob (8 hli) thiab lub cuab yeej nws tus kheej.

Nws raug nquahu kom koj nyeem cov lus qhia ua ntej siv.

Cov tsos ntawm cov tshuaj insulin ua rau lub neej yooj yim dua rau cov neeg mob ntshav qab zib, thiab SoloStar koob txhaj tshuaj tsis muaj qhov zam. Cov no yog cov tshuaj insulin pov tseg.

Tsim rau kev siv tus kheej nkaus xwb, kom tsis txhob muaj kev pheej hmoo kis mob. Txhua qhov kev txhaj tshuaj yuav tsum tau siv cov koob tshiab, uas yuav tsum tau txhaj tso ua ntej kev qhia ntawm insulin.

Tom qab siv tas, tus kov raug kaw nrog lub hau, rab koob tau muab tshem tawm ua ntej. Nws yog siv nrog insulin "Insuman Comb 25".

Humulin Quick cwj mem

Lub QuickPen koob txhaj tshuaj tsis tau zoo tshaj nyob rau hauv muaj koob npe rau lwm cov tuam ntxhab. Haum rau cov poj niam cev xeeb tub uas muaj ntshav qab zib hom 2. Autopen classic syringe mem thiab Humulin Rapid yog cov thawj coj hauv khw.

Tsis zoo li thawj qhov kev xaiv, QuickPen cwj mem yog pov tseg, caij nyoog nrog Humalog npaj. Tom qab txhua tus siv ntawm Humulin, lub cuab yeej raug muab pov tseg, tus xaum yuav tsum tau hloov pauv.

Cov khoom siv suav nrog 5 xaum ntawm 3 ml ntawm kev daws hauv txhua.

Ntsej muag ntawm cov xaum qhuav

Ib qho tshwj xeeb ntawm cov khoom siv ntawd yog tias rau kev qhia ntawm ntau hom insulin, koj tsis tas yuav tsum tau mus rau txoj kev pab ntawm neeg txawv. Hauv thawj kis, lub pob laub pov tseg kav ntev txog 30 hnub, tom qab ntawd nws tau muab pov tseg.

Hauv ob - cov cuab yeej siv rov qab tau muaj cov roj cartridges uas muab kev siv cwj mem lub sijhawm ntev txog li 3 xyoos. Ib qho tseem ceeb yog cov tuam ntxhab tsim cov npiv thiab cov cartridges ntawm tib lub hom, yog li kom tsis txhob pom lub txim tsis pom zoo, nws zoo dua los yuav ob qho tib si ntawm cov khoom ntawm tib lub koob.

Txwv tsis pub, cov tshuaj tsawg dua lossis ntau dua nkag mus rau hauv lub cev.

Yuav Tsum Muaj Cov Nta

Ib qho ntawm cov cwj pwm tseem ceeb uas tus cwj mem yuav tsum muaj yog ntsuas ntsuas kev ntsuas kom zoo dua. Nws raug suav tias yog qhov kev xaiv zoo tshaj plaws thaum rab phom txhaj tshuaj tsis muaj ntau tshaj 10 PIECES, thaum kos cim tau ua nyob rau hauv txoj kev uas tus nqi ntawm ib qhov cuab yeej yog 0.25 PIECES.

Nws yog ib qho tseem ceeb kom them sai sai rau qhov pom ntawm lub cuab yeej. Txhua qhov kev faib tawm yuav tsum nyob ntawm ntau qhov deb ntawm txhua lwm yam kom tus neeg mob tsis muaj teebmeem nrog xaiv cov koob tshuaj.

Qhov no yog qhov tseeb tshwj xeeb tshaj yog rau cov neeg laus thiab rau cov neeg siv uas tsis pom kev zoo.

Yuav siv kom raug li cas?

Ua ntej yuav ib lub cuab yeej, muaj ntau tus neeg xav txog nws yooj yim npaum li cas nws yuav siv rau hauv lub neej txhua hnub. Tsis yog txhua tus neeg muaj peev xwm ntawm nws tus kheej, yam tsis muaj kev pab ntawm tus neeg sab nraud, coj tus txheej txheem rau kev txhaj tshuaj insulin, ntxiv roj rau hauv lub khob uas hloov tau. Tus kws kho mob yuav tsum piav qhia rau tus neeg mob tias yuav siv tus cwj mem li cas.

Ua ntej kev txhaj tshuaj, koj yuav tsum siv sijhawm li 12 lem. Qhov kov kov tig 180 degrees. Qhov no yog ua kom tusyees sib xyaw cov ntsiab lus ntawm cov phom hauv daim cartridge. Lub qhov rai pob tshab yog qhov chaw nyob hauv lub cev ntawm lub cuab yeej, uas pab tus neeg mob hauv kev qhia hauv koob tshuaj.

Txhawm rau txhaj tshuaj insulin hauv qab daim tawv nqaij, lub pob nyem yog nias thiab tom qab 10 seconds lub koob raug tshem tawm ntawm lub cev.

Siv rab koob dab tsi?

Thaum xaiv cov cuab yeej siv, nws tseem yog qhov tseem ceeb yuav tsum tau them sai sai rau qhov zoo ntawm cov koob, vim tias rau cov tshuaj insulin qhov no yog qhov tseem ceeb heev. Kev ntsuas ntawm qhov mob thaum tswj hwm kev siv tshuaj yog nyob ntawm seb lub koob tau hnyav npaum li cas.

Ntawm kev muag khoom muaj cov koob ntawm ntau yam tuab, uas ua rau nws tuaj yeem nqa tawm kev txhaj tshuaj yam tsis muaj kev phom sij ntawm kev nkag mus rau cov leeg nqaij.

Nws yog ib qho tseem ceeb yuav tsum siv rab koob ntev li 4-8 hli ntev vim tias lawv yuag dua, thiab qhov no tswj txoj kev siv tshuaj.

Cov ntaub ntawv tsuas yog muab rau cov xov xwm dav dav xwb thiab tsis tuaj yeem siv rau kev kho tus kheej. Tsis txhob muab tshuaj rau nws tus kheej, nws tuaj yeem yog qhov txaus ntshai. Nco ntsoov koj tus kws kho mob. Nyob rau hauv cov ntaub ntawv ntawm ib nrab lossis tag nrho cov ntaub ntawv luam tawm los ntawm lub xaib, ib qho kev sib txuas mus rau nws yog qhov yuav tsum tau ua.

Cia rau cov mob Vosulin Pen Royal insulin koob txhaj tshuaj

Txhob nyob ze cov me nyuam.

Ncua rau sc thawj coj.

10 ml - iav fwj (1) - thawv ntawv thawv.
3 ml - cartridges (1) - hlwv pob (1) - pob khoom los ntawm cardboard.

Rau kev tswj hwm sc xwb. Cov koob tshuaj ntawm cov tshuaj tau txiav txim siab los ntawm tus kws kho mob tshwj xeeb hauv txhua kis, raws li kev mloog zoo ntawm cov piam thaj hauv cov ntshav.

Qhov nruab nrab, koob tshuaj txhua hnub los ntawm 0.5 txog 1 IU / kg lub cev qhov hnyav (nyob ntawm tus neeg qhov yam ntxwv ntawm tus neeg mob thiab qhov hnyav ntawm cov ntshav qab zib).

Sab nyhuv vim muaj cov nyhuv ntawm metabolism metabolism: hypoglycemic tej yam kev mob (pallor ntawm daim tawv nqaij, nce tawm hws, palpitations, tshee tshee, tshaib plab, ntxhov siab, lub plab ntawm lub qhov ncauj, mob taub hau, kiv taub hau, tsis pom kev zoo nkauj). Kev mob ntshav qog ntshav qis tuaj yeem ua rau txhim kho kev mob hypoglycemic coma.

Kev tsis haum tshuaj: daim tawv nqaij ua pob, Quincke's edema, anaphylactic poob siab.

Cov tshuaj tiv thaiv hauv zos: hyperemia, o thiab khaus ntawm qhov chaw txhaj tshuaj, nrog rau siv sijhawm ntev - lipodystrophy ntawm thaj chaw txhaj tshuaj.

Lwm yam: o, cov txav zuj zus hauv qhov pom tseeb (feem ntau thaum pib kho).