Diabefarm - cov lus qhia ua haujlwm rau kev siv

LUS QHIA
rau kev siv tshuaj kho mob

Kev sau npe:

Lub npe Kev Lag Luam: Diabefarm ®

Lub Npe Tsis Muaj Npe International: gliclazide

Dosage daim ntawv: ntsiav tshuaj

Muaj pes tsawg leeg:
1 ntsiav tshuaj muaj
Yam tshuaj muaj sia: gliclazide 80 mg
Cov muaj tswv yim: lactose monohydrate (mis nyuj muaj suab thaj), povidone, magnesium stearate.

Kev piav qhia
Cov ntsiav tshuaj ntawm cov xim dawb los yog dawb nrog lub xim daj ua ke yog tiaj-cylindrical nrog chamfer thiab hla-txoj kev pheej hmoo.

Cov tshuaj pab pawg kho mob: hypoglycemic tus neeg sawv cev rau kev tswj hwm qhov ncauj ntawm sulfonylurea pab pawg ntawm tiam thib ob

ATX Cov Cai: A10VB09

Pharmacological kev txiav txim
Cov Tshuaj Hauv Tshuaj
Glyclazide stimulates qhov tsim nyog ntawm insulin los ntawm pancreatic cells-hlwb, txhim kho cov insulin-secretory nyhuv ntawm cov piam thaj, thiab nce qhov rhiab heev ntawm cov ntaub so ntswg peripheral rau insulin. Tsim kho kev ua ub no ntawm intracellular enzymes - nqaij hlav glycogen synthetase. Txo lub sijhawm lub sijhawm txij li lub sijhawm noj mov kom txog thaum pib cov kua dej tso kua mis. Nws rov kho lub sijhawm thaum ntxov ntawm insulin secretion (tsis zoo li lwm yam sulfonylurea derivatives, uas muaj qhov cuam tshuam tshwj xeeb tshaj yog nyob rau theem thib ob ntawm kev zais cia). Txo cov postprandial nce nyob rau hauv cov ntshav qabzib.
Ntxiv rau kev cuam tshuam rau cov roj metabolism hauv lub cev, nws txhim kho microcirculation: nws txo cov platelet adhesion thiab kev sib sau ua ke, normalizes vascular permeability, tiv thaiv kev txhim kho ntawm microthrombosis thiab atherosclerosis, thiab rov kho cov txheej txheem ntawm physiological parietal fibrinolysis. Txo vascular receptor rhiab heev rau adrenaline. Txo cov kev txhim kho uas mob ntshav qab zib retinopathy nyob rau ntu ieproliferative. Nrog rau cov ntshav qab zib nephropathy nrog siv ntev, muaj qhov tseem ceeb txo qhov hnyav ntawm cov proteinuria. Nws tsis ua rau kom nce hauv lub cev nyhav, vim nws muaj cov teebmeem tseem ceeb ntawm kev xav thaum ntxov ntawm insulin secretion thiab tsis ua rau hyperinsulinemia, pab txo lub cev qhov hnyav hauv cov neeg mob rog nrog kev noj zaub mov kom tsim nyog. Nws muaj cov khoom ua rau anti-atherogenic, txo qis qhov kev tso tawm ntawm cov roj (cholesterol) hauv cov ntshav.
Cov Tshuaj Pharmacokinetics
Tom qab kev tswj hwm ntawm qhov ncauj, nws nrawm rau hauv lub plab zom mov. Kev tshem tawm yog qhov siab. Tom qab kev tswj hwm qhov ncauj ntawm 80 mg, qhov siab tshaj plaws nyob rau hauv cov ntshav (2.2-8 μg / ml) tau tiav tom qab li 4 teev, tom qab kev siv 40 mg, qhov siab tshaj plaws hauv cov ntshav (2-3 μg / ml) tau tiav tom qab 2-3 teev. nrog plasma cov protein - 85-97%, cov khoom faib tawm - 0.35 l / kg. Kev sib luag ntawm cov ntshav hauv cov ntshav tau mus txog tom qab 2 hnub. Nws yog metabolized hauv daim siab, nrog rau kev tsim ntawm 8 metabolites.
Tus nqi ntawm qhov tseem ceeb ntawm cov metabolite pom hauv cov ntshav yog 2-3% ntawm tag nrho cov tshuaj ntawm cov tshuaj noj, nws tsis muaj cov nyhuv hypoglycemic, tab sis nws txhim kho microcirculation. Nws yog tawm los ntawm lub raum - 70% nyob rau hauv daim ntawv ntawm metabolites, tsawg dua 1% hauv daim ntawv tsis hloov pauv, los ntawm txoj hnyuv - 12% hauv daim ntawv ntawm metabolites.
Ib nrab-lub neej yog 8 mus rau 20 teev.

Kev ntsuas rau siv
Hom 2 mob ntshav qab zib mellitus rau cov laus ua ke nrog kev kho kev noj haus thiab ua kom lub cev qoj ib ce nrog rau qhov kawg tsis ua hauj lwm zoo.

Cov Yuav Tsum Muaj
Hypersensitivity rau cov tshuaj, hom 1 mob ntshav qab zib mellitus, mob ntshav qab zib ketoacidosis, mob ntshav qab zib precoma, mob ntshav qab zib tsis nco qab, hyperosmolar coma, mob nyhav hnyav thiab / lossis lub raum tsis ua haujlwm, kev phais mob loj, kev kub hnyiab ntev, kev raug mob loj thiab lwm yam mob uas yuav tsum tau kho insulin, mob hnyuv, paresis mob plab, tej yam mob nrog kev noj cov zaub mov malabsorption, kev txhim kho hypoglycemia (kab mob kis), kab mob leukopenia, cev xeeb tub, pub niam mis, menyuam yaus ozrast mus txog 18 xyoo.

Nrog saib xyuas (qhov xav tau kev saib xyuas ntau ntxiv thiab xaiv cov tshuaj) yog kev kho rau cov mob febrile syndrome, kev quav dej cawv thiab lub qog (nrog rau kev ua haujlwm tsis zoo).

Siv thaum cev xeeb tub thiab lactation
Cov tshuaj yog contraindicated thaum cev xeeb tub thiab thaum pub mis.
Thaum cev xeeb tub tshwm sim, cov tshuaj yuav tsum tau txiav tam sim ntawd.

Tsuas tshuaj thiab tswj hwm
Cov koob tshuaj ntawm cov tshuaj tau teeb tsa ua ib tus zuj zus, nyob ntawm lub hnub nyoog ntawm tus neeg mob, cov lus qhia soj ntsuam ntawm tus kab mob thiab cov theem ntawm cov ntshav ceev ceev thiab 2 teev tom qab noj mov. Thawj koob tshuaj txhua hnub yog 80 mg, koob tshuaj txhua hnub yog 160 mg, thiab qhov siab tshaj txhua hnub yog 320 mg. Diabefarm noj tau qhov ncauj noj 2 zaug hauv ib hnub (sawv ntxov thiab yav tsaus ntuj) 30-60 feeb ua ntej noj mov.

Sab sij huam
Kev ntshav siab (nyob rau hauv kev ua txhaum ntawm qhov ntau npaum ntawm kev noj tshuaj thiab kev noj zaub mov tsis zoo): mob taub hau, hnov ​​nkees, tshaib plab, tawm hws, mob tsis muaj zog, txhoj puab heev, ntxhov siab, chim siab, poob siab thiab qeeb dhau qhov tshwm sim, kev nyuaj siab, pom tsis meej, mob tob tob, tshee tshee, zoo li tsis meej pem, kiv taub hau. , ploj ntawm kev tswj tus kheej, delirium, convulsions, hypersomnia, tsis nco qab, ua pa nyuaj, bradycardia.
Kev tsis haum tshuaj: khaus, urticaria, maculopapular pob.
Los ntawm cov kabmob hemopoietic: anemia, thrombocytopenia, leukopenia.
Los ntawm lub plab zom mov: dyspepsia (xeev siab, zawv plab, zoo nkaus li qhov hnyav hauv epigastrium), tsis nco qab - mob hnyav zuj zus thaum noj nrog zaub mov, lub siab ua haujlwm tsis zoo (cholestatic jaundice, kev ua haujlwm ntawm "siab" transaminases).

Noj ntau dhau
Cov tsos mob: hypoglycemia yog ua tau, mus txog rau kev txhim kho hypoglycemic coma.
Kev Kho Mob: yog tias tus neeg mob nco qab, noj cov zaub mov carbohydrates (qab zib) yooj yim sab hauv, muaj qhov tsis nco qab zoo, 40% dextrose (kua nplaum) daws yog tso tshuaj, 1-2 mg ntawm glucagon intramuscularly. Tom qab nws rov qab nco qab, tus neeg mob yuav tsum tau muab cov zaub mov muaj nplua nuj nyob hauv kev zom cov zaub mov tau yooj yim (kom tsis txhob rov qab txhim kho kev mob ntshav qab zib tsawg). Nrog rau lub paj hlwb edema, mannitol thiab dexamethasone.

Kev cuam tshuam nrog lwm yam tshuaj
Angiotensin-converting enzyme inhibitors (captopril, enalapril), H2-histamine receptor blockers (cimetidine), tshuaj tua kab mob (miconazole, fluconazole), tsis-tshuaj steroidal anti-inflammatory tshuaj (phenylbutazoflubrate, indigo), tshuaj tiv thaiv cov nyhuv hypoglycemic ntawm Diabefarma (ethionamide), salicylates, coumarin anticoagulants, anabolic steroids, beta-blockers, cyclophosphamide, chloramphenicol, monoamine oxidase inhibitors, su. fanilamidy ntev txiav txim, fenfluramine, fluoxetine, pentoxifylline, guanethidine, theophylline, cov tshuaj uas thaiv tubular secretion, reserpine, bromocriptine, disopyramide, pyridoxine, allopurinol, ethanol thiab etanolsoderzhaschie npaj, raws li zoo li lwm yam hypoglycemic tshuaj (acarbose, biguanides, insulin).
Weaken lub hypoglycemic effect ntawm Diabefarma barbiturates, glucocorticosteroids, sympathomimetics (epinephrine, clonidine, ritodrine, salbutamol, terbutaline), phenytoin, qeeb calcium calcium blockers, carbonic anhydrase inhibitors, thiazide azolefenudenate, triazium, trylzibine, triazia , diazoxide, isoniazid, morphine, glucagon, rifampicin, cov thyroid hormones, cov roj ntsha lithium, hauv cov koob tshuaj ntau - nicotinic acid, chlorpromazine, estrogens thiab tshuaj tiv thaiv qhov ncauj muaj lawv.
Thaum sib tham nrog ethanol, ib qho kev xav tsis meej li disulfiram muaj peev xwm ua tau.
Diabefarm tsub kom muaj kev pheej hmoo ntawm ventricular extrasystole thaum noj cov tshuaj glycosides.
Beta-blockers, clonidine, reserpine, guanethidine tuaj yeem npog qhov chaw kho mob tshwm sim ntawm hypoglycemia.
Cov tshuaj noj uas ua kom cov leeg hlwb hematopoiesis ua rau muaj kev pheej hmoo ntawm myelosuppression.

Cov lus qhia tshwj xeeb
Kev saib xyuas Diabefarm yog ua nrog cov khoom noj uas tsis muaj calorie ntau, pluas noj qis. Nws yog ib qho tsim nyog yuav tau soj ntsuam cov piam thaj hauv cov ntshav ntawm lub plab tas thiab tom qab noj mov.
Kev phais mob lossis nrog kev decompensation ntawm cov ntshav qab zib, nws yog qhov yuav tsum xav txog qhov siv tau los ntawm kev npaj tshuaj insulin.
Nws yog ib qho tsim nyog los ceeb toom cov neeg mob txog kev pheej hmoo ntawm kev mob ntshav qab zib ntau thaum muaj kev noj tshuaj ethanol, tsis muaj tshuaj tiv thaiv kev tsis haum tshuaj, kev tshaib plab. Hauv kev ua haujlwm ntawm ethanol, nws kuj tseem muaj peev xwm los tsim muaj disulfiram-syndrome xws li (mob plab, xeev siab, xeev siab, ntuav, mob taub hau).
Nws yog ib qho tsim nyog yuav tau hloov qhov koob tshuaj ntawm lub cev nrog lub cev lossis lub siab lub ntsws dhau los, hloov pauv kev noj haus
Tshwj xeeb tshaj yog rhiab rau qhov kev txiav txim ntawm cov tshuaj hypoglycemic yog cov neeg laus, cov neeg mob tsis tau txais kev noj haus zoo, cov neeg mob lub cev tsis muaj zog, cov neeg mob raug kev txom nyem los ntawm pituitary-adrenal tsis txaus.
Thaum pib kho mob, thaum xaiv cov koob tshuaj rau cov neeg mob nquag txog kev txhim kho ntawm lub qog ntshav qab zib, nws tsis raug nquahu kom koom nrog cov haujlwm uas xav tau kev nce siab thiab ceev ntawm cov kev tiv thaiv psychomotor.

Daim ntawv tso tawm
80 mg ntsiav tshuaj
Ntawm 10 ntsiav tshuaj nyob rau hauv lub hlwv sawb ntim los ntawm ib zaj duab xis ntawm polyvinyl chloride thiab ib daim ntawv luam ntawm txhuas ntawv ci varnished.
3 lossis 6 lub hlwv nrog cov lus qhia rau kev siv raug muab tso rau hauv pob ntawv ntawm cardboard.

Cia rau cov neeg mob
Sau npe B. Hauv qhov chaw qhuav thiab tsaus ntawm qhov kub uas tsis kub tshaj 25 ° C.
Txhob nyob ze cov me nyuam.

Hnub tas sij hawm
2 xyoos
Tsis txhob siv tom qab hnub tas sij hawm.

Cov Cai Siv Tshuaj So
Los ntawm tshuaj.

Kev thov nyiaj yuav tsum tau hais rau tus neeg tsim khoom:
FARMAKOR NTAU LAWM LLC, Russia
Chaw Nyob Ntau Lawm:
198216, St. Petersburg, Leninsky Prospect, d.140, lit. F
Chaw nyob raug cai:
Xyoo 194021, St. Petersburg, 2nd Murinsky Prospect, 41, lit. A