Fervex rau cov laus, txiv qaub tsis muaj qab zib - cov lus qhia ntawm kev siv

Fervex rau cov neeg laus uas tsis muaj suab thaj

Fervex rau cov neeg laus uas tsis muaj suab thaj (Fervex rau cov neeg laus tsis muaj piam thaj dawb)

Yam ntxwv ntawm lub cev-tshuaj lom neeg tus yam ntxwv: lub teeb beige ntau cov hmoov,

Muaj pes tsawg leeg. 1 sachet muaj xws li pheniramine maleate 25 mg, paracetamol 500 mg, ascorbic acid 200 mg,

lwm yam: mannitol, anhydrous citric acid, povidone, trimagnium dicitrate anhydrous, aspartame (hloov qab zib), Antillean ntuj tsw.

Daim ntawv tso tawm tshuaj.

Hmoov rau kev daws rau sab hauv kev siv.

Cov tshuaj pab pawg kho mob.

Kev muab tshuaj ntsuab thiab tshuaj tiv thaiv kev npau suav. PBX code N02B E51.

Tshuaj ua.

Lub hauv paus ntawm cov tshuaj Fervex yog kev sib xyaw ntawm cov tshuaj muaj txiaj ntsig zoo thiab muaj kev nyab xeeb uas ua rau cov kev sib txuas tseem ceeb hauv lub pathogenesis ntawm kev mob khaub thuas. Paracetamol muaj qhov ua rau antipyretic thiab analgesic effect, ascorbic acid - them nyiaj rau lub cev lub cev xav tau cov vitamin C, uas nce nrog qhov mob khaub thuas, pheniramine maleate - blocker ntawm H1-histamine receptors, muab cov nyhuv desensitizing, uas yog manifested los ntawm kev txo qis ntawm cov tshuaj tiv thaiv kab mob ntawm lub qog ua pa ntawm lub qaum ua pa (qhov ntswg txhim kho) , los ntswg tsawg zuj zus, txham thiab lacrimation ploj). Npaj ua cov tshuaj tov sov nrog kev saj qab ntxiag thiab aroma, cov tshuaj txo cov kev cuam tshuam ntawm intoxication.

Cov Tshuaj Pharmacokinetics

Paracetamol tom qab lub qhov ncauj tswj hwm tau sai thiab yuav luag txhua yam hauv lub plab zom mov. Qhov siab tshaj plaws ntawm paracetamol hauv ntshav tau tiav 30-60 feeb tom qab kev tswj hwm. Paracetamol yog metabolized tsuas yog nyob hauv daim siab los ua cov sib txuas nrog glucuronic acid thiab sulfates. Hauv ib qho nyiaj me me (tsawg dua 4%) nws yog metabolized los ntawm oxidation nrog kev tsim cov cysteine ​​thiab mercaptopuric acid (nrog kev koom nrog cytochrome P450).

Nws yog tawm hauv cov zis, feem ntau hauv cov qauv ntawm cov khoom noj khoom haus. Kwv yees li 5% ntawm qhov kev noj tshuaj tau muab tshem tawm tsis pauv.

Qhov kev tshem tawm ib nrab-lub neej ua rau 2–2, 5 teev. Lub cev metabolism ntawm paracetamol hauv cov neeg mob uas lub siab tsis ua haujlwm tsis hloov.

Ascorbic acid (vitamin C) yog yooj yim nqus hauv cov hnyuv. Tom qab kev nqus, nws circulates nyob rau hauv lub ntshav thiab concentrates nyob rau hauv lub qog endocrine. Nws pom nyob rau hauv ntau ntau hauv cortical thiab lub hlwb txheej ntawm lub qog adrenal. Qhov tshwj xeeb ntawm ascorbic acid hauv leukocytes thiab platelets ntau dua hauv ntshav ntshav. Ascorbic acid yog qee qhov hloov kho rau oxalic acid los yog lwm cov dej-soluble metabolites, thiab qee qhov raug tso tawm los ntawm lub raum hauv daim ntawv tsis hloov. Tus mob catabolism ntawm ascorbic acid yog 2, 2-4, 1% ntawm nws cov kev muab lub cev tag nrho, uas yog kwv yees li ntawm 1500 mg. Nws ntseeg tau tias qhov kev muab lub cev no txaus rau 1-1, 5 hlis vim tias tsis muaj cov vitamin C hauv zaub mov. Cov zis tawm hauv lub qhov zis pib tom qab txaus siab ntawm lub qhov xaim nrog ntau tshaj 1500 mg. Hauv cov neeg mob uas tsis tseg nyiaj, cov vitamin C yuav tsis tshwm sim nyob rau hauv cov zis txawm tias muab rau ntau hauv nrog lossis hauv lub cev. Ib nrab-lub neej ntawm ascorbic acid yog los ntawm 12, 8 txog 29, 5 hnub.

Pheniramine maleate tau zoo nqus los ntawm alimentary kwj dej thiab yooj yim nkag mus rau cov ntaub so ntswg. Ib nrab-lub neej los ntawm ntshav yog 1-1, 5 teev, nws yog tawm ntawm lub cev feem ntau los ntawm lub raum.

Kev ntsuas rau siv.

Cov kev kho mob ntawm tus mob khaub thuas, ua xua rhinitis, mob khaub thuas, rhinopharyngitis, uas tau tshwm sim los ntawm raws plab, mob taub hau, los ntswg, txham thiab lacrimation.

Txoj kev siv thiab koob tshuaj.

Sab hauv, rau cov neeg laus thiab menyuam yaus hnub nyoog 15 xyoos tshaj, cov tshuaj tau muab 1 pob 2-3 zaug ib hnub. Cov ntsiab lus ntawm lub hnab yog yaj nyob rau hauv lub khob ntawm dej txias lossis dej sov. Cov neeg mob uas muaj tsos mob khaub thuas yuav tsum tov nrog sov. Thawj koob tshuaj yuav tsum tau ua kom sai li sai tau tom qab qhov tsos pom ntawm thawj cov tsos mob ntawm tus kab mob. Kev daws yog tshwm sim tom qab npaj. Lub sijhawm nruab nrab ntawm cov koob tshuaj yuav tsum yog tsawg kawg 4 teev.

Lub chav kawm ntawm kev kho mob tsis pub dhau 3 hnub.

Sab sij huam.

Kev nkees nkees, lub qhov ncauj qhuav, cuam tshuam ntawm kev pab, tso zis cia, quav tawv, tsis txaus ntseeg thiab lub cim xeeb, tsis ua haujlwm zoo, tshwj xeeb tshaj yog rau cov neeg laus, tau.

Tsis tshua muaj qhov tsis haum, ua xua (ua pob ua pob, mob tso zis).

Tsis tshua muaj heev - thrombocytopenia, anemia, agranulocytosis, mob rwj.

Kev txwv kev txwv thiab sib kis hauv kev siv tshuaj.

Hypersensitivity rau lub Cheebtsam ntawm cov tshuaj,

kev ua rau lub siab thiab lub raum khiav tsis zoo,

nyiam ua kom thrombosis,

prostate adenoma,

tsawg dua 15 xyoos

phenylketonuria (vim tias cov tshuaj suav nrog aspartame),

Tshaj li qhov kev pom zoo ntawm kev noj tshuaj (noj ntau dhau).

Yog hais tias noj ntau dhau, ua rau cov tshuaj lom tshwm sim vim yog: pheniramine thiab paracetamol, uas tau pom los ntawm kev chua leeg, tsis hnov ​​qab, tsis nco qab lawm. Nws raug paub tias kev noj cov tshuaj paracetamol hauv ib koob ntau dua 4 g ib hnub (rau cov neeg laus) tuaj yeem ua rau lub siab tsis zoo thiab ua rau mob hepatonecrosis.

Cov tsos mob ntawm intoxication (xeev siab, ntuav, tsis nco qab, mob plab, tawm hws ntau) feem ntau tshwm sim hauv thawj 24 teev.

Kev Kho: Kho mob hauv tsev kho mob, kho mob plab zom mov, N-asethylcysteine, uas tau muab tshuaj rau hauv qhov ncauj los yog noj ntawm ncauj, methionine, kev siv tshuaj tua kab mob, siv rau thawj 10 teev raws li tshuaj tiv thaiv rau cov tshuaj paracetamol.

Cov yam ntxwv ntawm kev siv.

Siv nrog ceev faj hauv cov neeg mob ntshav qab zib.

Cawv ua kom cov nyhuv sedative ntawm pheniramine maleate, hepatotoxicity ntawm paracetamol.

Cov tshuaj yuav ua rau qaug zog, uas ua rau nws tsis zoo rau tsav tsheb thiab ua haujlwm nrog cov qauv.

Tsis muaj cov ntaub ntawv qhia txog qhov tshwm sim tsis zoo ntawm cov tshuaj rau kev xeeb tub thiab lactation, txawm li cas los xij, cov tshuaj yuav tsum tau tsim tawm rau lub sijhawm no nrog kev ceev faj, suav txog qhov kev pheej hmoo / cov txiaj ntsig sib piv.

Ascorbic acid tuaj yeem hloov cov kev ntsuas hauv chaw kuaj (ntshav qabzib, ntshav bilirubin, kev ua haujlwm transaminase).

Txhawm rau tiv thaiv kev noj ntau dhau, txhua yam kev npaj uas muaj cov tshuaj paracetamol yuav tsum raug qhia meej thiab tsis cais mus.

Rau cov neeg mob uas lub raum tsis ua haujlwm nrog creatinine tshem tawm

Daim ntawv noj tshuaj:

Muaj ib lub hnab:
cov tshuaj nquag: paracetamol - 0.500 g, ascorbic acid - 0.200 g, pheniramine txiv neej - 0.025 g.
zam txim: mannitol 3.515 g, citric acid 0.050 g, povidone KZO 0.010 g, magnesium citrate 0.400 g, aspartame 0.050 g, txiv qaub-rum tsw * 0.200 g.

Lub hmoov yog lub teeb beige. Blotches xim av raug tso cai.

Cov chaw muag tshuaj

Cov Tshuaj Hauv Tshuaj
Fervex ® yog kev sib xyaw ua ke uas muaj cov tshuaj paracetamol, pheniramine thiab ascorbic acid. Paracetamol yog qhov tsis-narcotic analgesic uas thaiv cyclooxygenase, feem ntau yog hauv nruab nrab lub paj hlwb, ua haujlwm ntawm qhov mob thiab thermoregulation chaw, thiab muaj cov nyhuv analgesic thiab antipyretic.
Pheniramine - H blocker₁-histamine receptors, txo rhinorrhea thiab lacrimation, tshem tawm spastic tshwm sim, o thiab hyperemia ntawm cov leeg mos ntawm lub qhov ntswg kab noj hniav, nasopharynx thiab paranasal sinuses. Ascorbic acid koom nrog kev tswj hwm ntawm cov txheej txheem redox, cov metabolism hauv kev ua kom rog, ntshav coagulation, kev tsim cov ntaub so ntswg, hauv kev sib txuas ntawm cov tshuaj hormones steroid, txo vascular permeability, txo qhov xav tau cov vitamins B.₁, Hauv₂, A, E, folic acid, pantothenic acid. Txhim kho qhov ua siab ntev ntawm paracetamol thiab lengthens nws cov nyhuv (cuam tshuam nrog kev txuas ntxiv ntawm T½).

Cov Tshuaj Pharmacokinetics
Paracetamol
Tom qab kev tswj hwm ntawm qhov ncauj, nws nqus tawm ntawm txoj hnyuv kom sai. Qhov siab tshaj plaws ntawm cov tshuaj hauv cov ntshav tau mus txog 10-60 feeb tom qab kev tswj hwm. Nws xa tawm sai heev hauv cov nqaij hauv lub cev, nkag mus rau cov ntshav-hlwb teeb meem. Kev sib txuas lus nrog cov protein ntshav yog qhov tsis txaus ntseeg thiab tsis muaj tus nqi kho, tab sis nce nrog qhov nce ntxiv.
Kev zom zaub mov tshwm sim hauv daim siab, 80% ntawm cov koob tshuaj coj mus rau hauv cov tshuaj tiv thaiv kab mob nrog glucuronic acid thiab sulfates los tsim cov tshuaj tiv thaiv tsis tau, 17% tau siv nrog hydroxylation nrog kev tsim ntawm 8 nquag metabolites, uas sib txuas nrog glutathione los ua ib qho kev tsis ua haujlwm lawm. Ib qho ntawm hydroxylated metabolic intermediates tso tawm cov tshuaj hepatotoxic. Cov metabolite no yog nruab nrab los ntawm kev sib xyaw nrog glutathione, txawm li cas los xij, nws tuaj yeem muaj ntau zuj zus thiab thaum muaj tshuaj paracetamol ntau dhau (150 mg ntawm paracetamol / kg lossis 10 g ntawm paracetamol qhov ncauj) ua rau mob hepatocyte necrosis. Nws yog tawm los ntawm lub raum hauv daim ntawv ntawm metabolites, feem ntau yog hauv daim ntawv ntawm conjugates. Hauv daim ntawv tsis hloov pauv, tsawg dua 5% ntawm qhov koob tshuaj noj tau zam. Qhov kev tshem tawm ib nrab-lub neej ua rau ntawm 1 mus rau 3 teev.
Feniramine:
Nws yog zoo nqus hauv cov hnyuv. Ib nrab-lub neej los ntawm ntshav ntshav yog los ntawm ib tus thiab ib nrab xuaj moos. Nws yog tawm feem ntau dhau ntawm ob lub raum.
Ascorbic acid:
Nws yog zoo nqus hauv cov hnyuv. Lub sijhawm los tsim cov kev kho mob siab tshaj plaws (TCmax) tom qab kev tswj hwm ntawm qhov ncauj yog -4 teev. Nws yog metabolized feem ntau hauv daim siab. Nws yog tawm los ntawm lub raum, los ntawm txoj hnyuv, nrog hws, tsis hloov pauv thiab hauv daim ntawv ntawm metabolites.

* Cov nplais muaj pes tsawg leeg: maltodextrin, acacia ntawm cov pos hniav, α-pinene, ß-pinene, limonene, γ-terpinene, linaloal, neral, α-terpineol, geranial, dextrose, silicon dioxide Е551, butylhydroxyanisole.

Kev ntsuas rau siv

Nws yog siv rau cov mob ua pa, mob khaub thuas ua pa, kis mob rhinopharyngitis los kho cov tsos mob hauv qab no:

• rhinorrhea, ntswg ntswg,
• mob taub hau
• npaws
• lacrimation
• txham.

Cov Yuav Tsum Muaj

• Hypersensitivity rau paracetamol, ascorbic acid, pheniramine lossis lwm yam tshuaj ntawm cov tshuaj.
• Cov kab mob voos thiab mob rau sab hauv ntawm txoj hnyuv huam (hauv ntu mob).
• Daim siab ua haujlwm.
• Lub qhov muag kaw lub ntsej muag daj ntseg.
• Kev tso zis tso zis cuam tshuam nrog cov kab mob prostate thiab mob tso zis.
• Portal tawg.
• Kev quav cawv
• Phenylketonuria.
• Cov menyuam yaus lub hnub nyoog (txog 15 xyoos).
• Cev xeeb tub thiab lactation (kev nyab xeeb tsis tau kawm).

Nrog saib xyuas

Mob raum tsis ua hauj lwm, mob ntshav siab thaum yug los ua ntshav (Gilbert, Dubin-Johnson thiab Rotor syndromes), kab mob siab, kis mob rau daim siab, dej cawv siab, hnub nyoog qib siab.

Siv thaum cev xeeb tub thiab thaum pub niam mis

Kev tshawb nrhiav kev coj ua zoo thiab kev tswj hwm ntawm cov tshuaj Fervex ® hauv cov poj niam cev xeeb tub tsis tau ua, yog li kev siv tshuaj nyob hauv pawg neeg mob no tsis pom zoo.

Kuj tsis paub meej tias cov tshuaj yeeb dej caw puas yuav kis mus rau niam mis. Cov tshuaj yuav tsum tsis txhob siv thaum lactation.

Tsuas tshuaj thiab tswj hwm

Sab hauv - 1 sachet 2-3 zaug ib hnub. Ua ntej siv, cov ntsiab lus ntawm lub hnab yuav tsum tau yaj nyob rau hauv lub khob (200 ml) ntawm dej sov. Lub sijhawm ua haujlwm siab tshaj plaws yog 5 hnub. Qhov siab tshaj plaws niaj hnub noj tshuaj paracetamol yog 4 g (8 pob ntawm cov tshuaj Fervex ®) nrog lub cev hnyav tshaj 50 kg. Lub sijhawm nruab nrab ntawm kev txhaj tshuaj yuav tsum yog tsawg kawg 4 teev.
Hauv cov neeg mob uas lub raum tsis ua haujlwm (ua kom tus kabmob muaj peev xwm ua kom tsis muaj kabmob ®. Tsis tas li ntawd, ethanol, thaum siv pheniramine, ua rau muaj kev txhim kho ntawm tus mob ua paug nrog leeg).
Pheniramin uas yog ib feem ntawm kev npaj Fervex ® txhim kho cov nyhuv ntawm sedatives: morphine derivatives, barbiturates, benzodiazepines thiab lwm cov tshuaj tiv thaiv kab mob, tshuaj tiv thaiv tshuaj tiv thaiv (meprobamate, phenogiazine derivatives), tshuaj tiv thaiv kab mob (amitriptyline, mirtazapine, mianserin) ntawm cov tshuaj tiv thaiv.₁-blockers, baclofen, thaum tsis tsuas yog nce lub sedative effect, tab sis kuj nce kev pheej hmoo ntawm kev phiv ntawm cov tshuaj (tso zis cia, lub qhov ncauj qhuav, cem quav).
Nws yog qhov yuav tsum tau coj mus rau hauv tus lej muaj peev xwm txhim kho lub hauv paus atropine-zoo li cov tshuaj tiv thaiv thaum siv los ua ke nrog lwm yam tshuaj nrog cov tshuaj anticholinergic (lwm cov tshuaj antihistamines, imipramine pawg antidepressants, phenothiazine antipsychotics, m-anticholinergic tshuaj, atropine-zoo li antispasmodic tshuaj, disopyramide).
Thaum siv cov tshuaj, ua ke nrog microsomal oxidation inducers: barbiturates, tricyclic antidepressants, anticonvulsants (phenytoin), flumecinol, phenylbutazone, rifampicin thiab ethanol, qhov kev pheej hmoo ntawm hepatotoxicity yog nce ntau (vim yog cov tshuaj paracetamol).
Glucocorticosteroids nrog rau kev siv ua ke ua rau muaj kev pheej hmoo ntawm kev mob qog ntshav.
Nkag mus nrog rau salicylates tsub kom qhov pheej hmoo ntawm nephrotoxicity.
Nrog rau kev siv ua ke nrog chloramphenicol (chloramphenicol), lub tshuaj lom ntawm cov tom kawg nce ntxiv.
Paracetamol muaj nyob hauv cov tshuaj pab txhim kho cov txiaj ntsig ntawm kev tiv thaiv tsis tau thiab txo qhov ua tau ntawm cov tshuaj uricosuric.

Cov lus qhia tshwj xeeb

Cov tshuaj tsis muaj suab thaj thiab tuaj yeem siv los ntawm cov neeg mob ntshav qab zib mellitus.
Fervex ® yuav tsum tsis txhob siv nrog lwm cov tshuaj muaj paracetamol. Txhawm rau kom tsis txhob ua rau lub siab ua rau lub siab ua rau mob hlwb, paracetamol yuav tsum tsis txhob haus nrog dej cawv, thiab tseem yuav tsum tau nqa los ntawm cov neeg muaj feem cuam rau kev haus cawv ntau.
Txoj kev pheej hmoo ntawm kev tsim daim siab ua rau lub siab ntxiv rau cov neeg mob uas haus dej cawv.
Thaum dhau qhov kev pom zoo ntau npaum li cas thiab nrog siv ntev, ib qho kev cia siab ntawm cov tshuaj yuav tshwm sim.
Txhawm rau kom tsis txhob noj tshuaj paracetamol ntau dhau, koj yuav tsum paub tseeb tias tag nrho cov tshuaj paracetamol uas muaj nyob hauv txhua cov tshuaj uas tus neeg mob noj tsis dhau 4 g.

Cuam tshuam rau kev muaj peev xwm tsav tsheb thiab tshuab

Muab qhov tseem ntawm kev tsim cov kev tsis txaus siab xws li tsaug zog thiab kiv taub hau, nws raug nquahu kom tsis txhob tsav tsheb thiab cov txheej txheem thaum lub sijhawm kho nrog cov tshuaj.

Chaw tsim tshuaj paus

Chaw tsim tshuaj paus, ntim khoom (ntim thawj), ntim (ntim theem nrab / ntim khoom ntim), muab cov khoom tswjhwm zoo
UPSASAS, Fab Kis
979 Avenue de Pyrenees, 47520 Le Pass, Fab Kis UPSASAS, Fab Kis
979 txoj kev des Pyrenees, 47520 Daim Ntawv Lees, Fab Kis

Kev thov cov neeg tau txais kev pabcuam yuav tsum tau xa rau:
Bristol-Myers Squibb LLC, Russia 105064, Moscow, ul. Zemlyanoy Val, 9

Cov koomhaum muaj txoj cai lij choj nyob rau hauv lawv lub npe sau npe rau daim ntawv pov thawj yog muab
UPSASAS, Fab Kis
3, ryu Joseph Monnier, 92500 Rueil-Malmaison, Fab Kis UPSASAS, Fab Kis
3, rue Joseph Monier, 92500 Rueil Malmaison, Fab Kis

Cov tshuaj muaj pes tsawg leeg

yam tshuaj: pheniramine maleate, paracetamol, ascorbic acid (vitamin C)

1 sachet muaj pheniramine maleate 25 mg, paracetamol 500 mg, ascorbic acid (vitamin C) 200 mg

tus zam: mannitol (E 421), citric acid, povidone, trimagnium dicitrate anhydrous, aspartame (E 951), antillean tsw.

Pharmacological pawg

Kev muab tshuaj ntsuab thiab tshuaj tiv thaiv kev npau suav. PBX code N02B E51.

Pharmacological teebmeem vim yog lub hauv paus ntawm cov tshuaj:

• Pheniramine Maleate - H blocker ₁ -histamine receptors, muab cov txiaj ntsig ua kom tsis zoo, tshwm sim los ntawm qhov kev txo qis hauv cov lus teb ntawm cov leeg mos ntawm lub hauv nruab nrab pa (ua pa ntawm lub qhov ntswg ua pa, txhaws ntswg, txham thiab lacrimation txo qis)
• paracetamol muaj cov nyhuv antipyretic thiab analgesic,
• ascorbic acid compensates lub cev xav tau cov vitamin C, loj hlob nrog khaub thuas.

Paracetamol tom qab lub qhov ncauj tswj hwm, nws tau nrawm thiab yuav luag nqus hauv lub plab zom mov. Qhov siab tshaj plaws ntawm paracetamol hauv cov ntshav ntshav tau mus txog 30-60 feeb tom qab kev tswj hwm. Paracetamol yog metabolized nyob rau hauv daim siab los ua cov sib txuas nrog glucuronic acid thiab sulfates.

Nws yog tawm hauv cov zis, feem ntau hauv cov qauv ntawm cov khoom noj khoom haus. 90% ntawm cov koob tshuaj noj tau tawm ntawm cov raum hauv 24 teev, feem ntau yog siv tshuaj sib xyaw nrog glucuronic acid (60-80%), sulfate conjugates (20-30%).

Hauv daim foos tsis hloov pauv, kwv yees li 5% ntawm qhov tshuaj noj tau muab cais tawm. Qhov kev tshem tawm ib nrab-lub neej yog kwv yees li 2:00.

Feniramine maleate zoo nqus hauv cov hnyuv. Nws yog tawm feem ntau dhau ntawm ob lub raum.

Ascorbic acid zoo nqus hauv cov hnyuv. Nws yog tawm hauv feem ntau nrog zis.

Cov kev kho mob ntawm tus mob khaub thuas, ua xua rhinitis, mob khaub thuas, rhinopharyngitis, tshwm sim los ntawm kub taub hau, mob taub hau, los ntswg, txham thiab lacrimation.

Kev tiv thaiv kev nyab xeeb zoo rau kev siv

Yog tias qhov kub ntawm lub cev lossis kub cev ntev, uas ua mob ntev txog 5 hnub tiv thaiv keeb kwm ntawm kev siv tshuaj lossis thaum pom tias muaj kev saib xyuas lub zog, koj yuav tsum sab laj nrog kws kho mob los txiav txim siab qhov ua tau ntawm kev siv tshuaj ntxiv.

Siv nrog ceev faj hauv cov neeg mob ntshav qab zib.

Cawv ua kom cov nyhuv sedative ntawm pheniramine maleate, hepatotoxicity ntawm paracetamol.

Ascorbic acid tuaj yeem hloov cov kev ntsuas hauv chaw kuaj (ntshav qabzib, ntshav bilirubin, kev ua haujlwm transaminase).

Txoj kev pheej hmoo ntawm kev pheej hmoo siab tshaj plaws yuav tshwm sim thaum tshaj cov tshuaj pom zoo thiab nrog kev kho mob ntev.

Txhawm rau tiv thaiv kev noj tshuaj ntau dhau, txhua qhov npaj muaj paracetamol yuav tsum kuaj xyuas thiab tshem tawm.

Rau cov neeg laus uas lub cev hnyav dua 50 kg, tag nrho cov tshuaj paracetamol yuav tsum tsis pub tshaj 4 g ib hnub.

Kev siv dej cawv los yog siv cov tshuaj sedatives (tshwj xeeb yog barbiturates) nce qhov sedative nyhuv ntawm pheniramine maleate, yog li ntawd, cov tshuaj yeeb dej caw yuav tsum zam thaum kho.

Noj ntau dhau

Txuam nrog pheniramine.

Kev noj tshuaj ntau dua ntawm pheniramine tuaj yeem ua rau qaug dab peg (tshwj xeeb yog hauv cov menyuam yaus), tsis hnov ​​qab nco qab, com.

Txuam nrog paracetamol.

Muaj kev pheej hmoo ntawm kev qaug cawv rau cov neeg laus thiab tshwj xeeb tshaj yog nyob rau cov menyuam yaus (cov neeg siv tshuaj lom ntau dhau thiab ua kom lom yog tsis haum).

Kev noj tshuaj paracetamol ntau dhau lawm tuaj yeem ua rau neeg tuag taus.

Xeev siab, ntuav, tsis nco qab, pallor, tawm hws ntau heev, mob plab, feem ntau tshwm sim hauv thawj 24 teev.

Kev noj tshuaj ntau tshaj 10 g ntawm paracetamol hauv 1 koob tshuaj rau cov neeg laus thiab 150 mg / kg ntawm lub cev qhov hnyav hauv 1 koob tshuaj rau cov menyuam yaus ua rau mob hepatic cytolysis, uas tuaj yeem ua kom tiav thiab tsis muaj kev cuam tshuam necrosis, uas ua rau hepatocellular tsis txaus, metabolic acidosis, encephalopathy, uas, hauv nws nyeg, tuaj yeem ua rau tsis nco qab thiab tuag.

Nyob rau tib lub sijhawm, muaj qhov nce ntawm hepatic transaminases, lactate dehydrogenase thiab bilirubin tiv thaiv keeb kwm ntawm ib qib nce ntawm prothrombin, uas tuaj yeem tshwm sim 12-48 teev tom qab thov.

• tsev kho mob sai
• kev txiav txim ntawm theem pib ntawm paracetamol hauv ntshav ntshav
• tam sim ntawd tshem tawm ntawm daim ntawv thov siv tshuaj los ntawm kev mob plab,
• kev kho cov pa tshaj rau suav nrog kev siv tshuaj tiv thaiv ntawm N-acetylcysteine ​​ua ke nrog cov tshuaj los sis noj ntawm qhov ncauj. Cov tshuaj tiv thaiv yuav tsum tau siv kom ntxov li ntxov tau, zoo dua li thaj tsam 10:00 tom qab siv tshuaj ntau dhau
• methionine ua kev kho cov tsos mob.

Sab sij huam

Los ntawm cov kab mob hematopoietic thiab lymphatic: anemia, sulfhemoglobinemia thiab methemoglobinemia (cyanosis, ua tsis taus pa, mob plawv), hemolytic anemia thrombosis, hyperprothrombinemia, erythrocytopenia, thrombocytopenia, agranulocytosis, neutrophilic leukocytosis, purpura, leukopenia.

Los ntawm lub nruab zog: anaphylaxis, anaphylactic ceeb, tawv nqaij tsis haum lub cev, nrog rau mob pruritus, tawm pob rau ntawm daim tawv nqaij thiab cov qog ua kua (feem ntau mob erythematous tawm pob, urticaria), mob angioedema, erythema multiforme (Stevens-Johnson syndrome), mob ua paug rau cov tawv nqaij ua paug (Lyell syndrome).

Los ntawm tus txheej txheem ua pa: bronchospasm hauv cov neeg mob rhiab rau acetylsalicylic acid thiab lwm yam NSAIDs.

Los ntawm lub plab zom mov: lub qhov ncauj qhuav, xeev siab, kub siab, ntuav, cem quav, mob epigastric, raws plab, ua kom lub siab ua haujlwm tsis zoo, muaj daim siab ua kom lub siab muaj zog, feem ntau tsis muaj nqaij hlav, mob hepatonecrosis (koob tshuaj tiv thaiv-siv nyhuv tshuaj).

Los ntawm cov kab ke endocrine: hypoglycemia txog hypoglycemic coma.

Los ntawm lub paj hlwb: tsis tshua muaj - mob taub hau, kiv taub hau, ntxhov siab txog kev pw tsaug zog, pw tsaug zog, tsaug zog, tsis meej pem, pom kev tsis meej, tshee tshee, tshee tshee, qee qhov mob - tsis nco qab, ntuav, dyskinesia, hloov cwj pwm, nce kev txob taus, tsis txaus ntseeg thiab nco qab, cuam tshuam tshwj xeeb, tshwj xeeb tshaj yog rau cov neeg laus muaj hnub nyoog.

Los ntawm cov kab mob plawv: nyob rau hauv raug mob cais tawm - tachycardia, myocardial dystrophy (koob tshuaj-siv nyhuv nrog lub sijhawm ntev), orthostatic hypotension.

Los ntawm sab ntawm cov metabolism: metabolic tsis txaus ntawm zinc, tooj.

Los ntawm cov kab mob urinary: tso zis cia thiab ua kom tso zis nyuaj, aseptic pyuria, lub raum tau rov qab los.

Ntawm daim tawv nqaij sab: eczema

Los ntawm sab hauv cov plab hnyuv siab raum ntawm lub zeem muag: qhov muag qhuav, mydriasis, kev pab cuam tshuam.

Nrog kev siv ntev hauv kev siv ntau: kev puas tsuaj rau lub plawv glomerular ntawm lub raum, crystalluria, kev tsim cov urate, cystine thiab / lossis oxalate calculi hauv lub raum thiab mob txeeb zig, ua rau puas rau insular apparatus ntawm lub txiav (hyperglycemia, glucosuria) thiab cov tshuaj tiv thaiv kab mob glycogen tuaj txog rau kev txhim kho ntshav qab zib mellitus.

Kev sib cuam tshuam nrog lwm yam tshuaj thiab lwm yam kev sib cuam tshuam

Vim tias muaj cov pheniramine ntau, ethanol nce qhov ua kom loog ntawm H ₁ cov khoom thaiv, yog li koj yuav tsum tsis kam tsav tsheb lossis ua haujlwm nrog lwm cov txheej txheem. Thaum kho lub sijhawm, kev haus cawv thiab siv cov tshuaj uas muaj dej cawv ethyl yuav tsum zam kom paub.

Kev sib xyaw ua ke yuav tsum tau muab rau hauv tus account.

Vim tias muaj pheniramine, lwm yam tshuaj ntxiv tuaj yeem ua rau muaj kev nyuaj siab ntawm cov hlab ntsha hauv nruab nrab, xws li morphine derivatives (analgesics, hnoos qog, thiab hloov kho), tshuaj tiv thaiv kabmob, barbiturates, benzodiazepines, anxiolytics, uas tsis yog benzodiazepines (e.g. meprobamate) , hypnotics, sedative cov tshuaj tiv thaiv kab mob (amitriptyline, doxepin, mianserin, mirtazapine, trimipramine), sedative N ₁ -blockers, central antihypertensive agents, baclofen thiab thalidomide.

Vim tias muaj pheniramine ntau, cov tshuaj uas muaj cov nyhuv atropine, xws li: imipramine antidepressants, feem ntau atropine N ₁ blockers, anticholinergics, antiparkinsonian tshuaj, atropine antispasmodics, disopramide, phenothiazine antipsychotics thiab clozapine tuaj yeem ntxiv cov teebmeem kev xav tsis txaus, xws li tso zis cia, quav tawv thiab qhov ncauj qhuav.

Teraflu: muaj pes tsawg leeg, kev txiav txim ntawm pharmacological

Cov cuab yeej muaj nyob rau hauv daim ntawv ntawm hmoov, ntsiav tshuaj, tshuaj pleev thiab tshuaj txau rau cov haujlwm hauv qhov ncauj. Nws muaj cov tshuaj paracetamol, pheniramine maleate thiab ascorbic acid.

Cov tshuaj muaj tshuaj muaj pes tsawg leeg, uas ua rau nws tsis tsuas yog cov tshuaj ua kom txias, tab sis kuj tso cai rau nws los ua ke nrog lwm cov tshuaj los ntawm tib pab pawg muag tshuaj.

Cov hmoov no nws txawv, yog li nws tshem tawm tag nrho cov cim ntawm khaub thuas thiab mob khaub thuas, txawm tias muaj ntshav qab zib. Yog li, nrog kev pabcuam ntawm cov tshuaj, koj tuaj yeem tshem tawm hnoos, ua npaws, los ntswg thiab mob caj pas. Tsis tas li, cov tshuaj ua rau lub zog tiv thaiv kab mob, thiaj li ua kom sai sai.

Feem ntau, Teraflu, zoo li Fervex, yog siv tsis muaj suab thaj rau cov kab mob xws li:

1. quav nyab ua npaws
2. mob npaws
3. mob hlab ntsws
4. rhinopharyngitis,
5. mob khaub thuas
6. mob ntsws npog
7. rhinorrhea
8. rhinosinusopathy thiab lwm yam.

Hais txog cov tsos mob, cov tshuaj muaj vasoconstrictor (phenylephrine), immunostimulating (vitamin C), antipyretic, analgesic (paracetamol), nrog rau cov tshuaj tiv thaiv ua xua (pheniramine).

Qhov zoo ntawm cov tshuaj yog tias nws txawv hauv daim ntawv thiab lub zog ntawm kev kis, uas tso cai rau cov neeg mob xaiv qhov kev xaiv zoo tshaj plaws.

Tab sis feem ntau, kev nyiam yog muab rau cov hmoov los ntawm cov dej kub tau npaj, vim lawv siv tau zoo thiab yooj yim siv.

Cov lus qhia rau kev siv tshuaj

Ib pob hmoov yog coj txhua plaub teev. Txawm li cas los xij, thaum nruab hnub koj tuaj yeem haus tsis pub ntau tshaj 4 hnab.

Ua ntej siv, cov khoom lag luam yuav tsum tau yaj nyob rau hauv lub khob ntawm cov dej rhaub. Nws yog tsim nyog sau cia tias cov neeg mob ntshav qab zib yuav tsum tsis txhob ntxiv qab zib rau hauv dej haus.

Cov tshuaj yog pub rau noj thaum lub sijhawm ntawm lub hnub. Txawm li cas los xij, nws muaj qhov ua tau zoo tshaj plaws yog tias koj haus nws ua ntej mus pw.

Haus luam yeeb cov khoom rau ntau tshaj 5 hnub sib law liag txwv tsis pub muaj. Tsis tas li ntawd, nws txoj kev siv tsuas yog pub txij li hnub nyoog kaum ob xyoos.

Nrog pom cov cim ntawm tus mob khaub thuas lossis mob khaub thuas, koj tuaj yeem xaiv txoj kev kho tsis yog tsuas yog raws li kev siv ntawm cov txiaj ntsig kho kom zoo, tab sis kuj yuav saj. Thiab qhov zoo tshaj plaws ntawm cov paracetamol (325 mg) muaj qhov siab tshaj plaws analgesic thiab antipyretic nyhuv.

Hauv cov qauv mob hnyav uas mob ua pa, koj tuaj yeem siv Teraflu Ntxiv, uas muaj saj ntawm cinnamon thiab kua. Ua ib feem ntawm cov khoom lag luam no, muaj ob qhov tshuaj ntxiv ntawm cov tshuaj nquag (650 mg). Qhov no tso cai rau koj kom ceev nrooj qhov ntsuas kub thiab txo qis kev siv ntawm lwm yam, tsis muaj tsawg lub cim ntawm tus kab mob.

Txawm li cas los xij, siv cov tshuaj nyob rau hauv daim ntawv ntawm hmoov tsis yog ib txwm yooj yim, vim tias ntau tus neeg mob ntshav qab zib, txawm tias mob khaub thuas, tuaj yeem mus ua haujlwm.

Hauv qhov no, lawv tuaj yeem siv Teraflu ntsiav tshuaj.

Fervex: muaj pes tsawg leeg, kho cov nyhuv, phiv thiab contraindications

Fervex yog cov hmoov pob zeb ua ke nrog lub teeb beige xim. Ib qho kua hnab muaj cov tshuaj paracetamol (500 mg) pheniramine maleate (25 g) thiab vitamin C (200 mg). Aspartame yog siv los hloov cov piam thaj.

Lub hauv paus ntawm cov tshuaj yog kev sib txuam ntawm cov tshuaj muaj txiaj ntsig zoo uas tshem tawm cov tsos mob ntawm tus mob khaub thuas. Yog li no, tom qab haus dej haus kub, qhov kub tsawg dua, qhov mob ntawm caj pas thiab lub taub hau poob, qhov mob tau mob siab thiab los ntshav lossis ntswg thiab lacrimation ploj.

Cov lus qhia rau kev siv Fervex yog tib yam li hauv Teraflu.

Hais txog cov kev mob tshwm sim, tom qab ntawd tom qab noj cov tshuaj, quav tawv, tsaug zog, nco tsis meej, tshuav yuav tshwm sim. Tso zis, chaw nyob ntxhov siab, qhov ncauj qhuav kuj tseem tuaj yeem ua tau, thiab cov neeg laus ua neeg tsis mloog lus. Tsawg tsawg zaus, tus neeg mob tuaj yeem ua rau muaj kev tsis haum (urticaria, tawm pob), qee zaum lub raum colic, thrombocytopenia, agranulocytosis, thiab mob ntshav txhaus hauv ntshav qab zib mellitus yuav tshwm sim.

Cov Txheej Txheem Siv rau Fervex siv yog:

1. nyiam ua ntshav txhaws,
2. muaj lub cev tsis haum rau lub tshuaj,
3. lub qhov muag kaw lub ntsej muag daj,
4. hnub nyoog txog 15 xyoos
5. quav cawv
6. prostate adenoma,
7. phenylketonuria,
8. lub raum thiab lub siab ua haujlwm.

Cov lus qhia rau kev siv

Koj tuaj yeem haus tau 2-3 daim tsaj nyob rau ib hnub. Tab sis ua ntej, cov ntsiab lus ntawm pob yuav tsum tau yaj nyob rau hauv lub khob ntawm dej sov los yog dej txias.

Cov lus qhia Fervex tsis muaj piam thaj rau kev siv hais tias thawj koob tshuaj zoo dua yuav tsim tau tam sim ntawd tom qab thawj cov tsos mob tshwm sim. Kev daws yuav tsum quag cawv sai tom qab npaj, thiab lub sijhawm nruab nrab ntawm koob tshuaj yuav tsum yog tsawg kawg 4 teev. Lub sijhawm kho mob tsis pub dhau peb hnub.

Yog tias qhov kev noj tshuaj ntau dua, kev noj tshuaj paracetamol thiab feniarmin tuaj yeem muaj cov tshuaj lom rau hauv lub cev, uas tau ua kom pom los ntawm kev cuam tshuam ntawm kev nco qab, tsis meej pem thiab tseem hnov ​​qab.

Kev noj tshuaj ntau dhau tuaj yeem tshwm sim yog tias cov koob tshuaj paracetamol rau cov neeg laus ntau dua 4 grams, uas tuaj yeem ua rau mob hepatonecrosis. Cov tsos mob ntawm intoxication yuav tshwm sim nruab hnub tom qab siv tshuaj Fervex. Txoj kev kho yog mob plab rwj thiab tswj hwm tus mob N-asethylcysteine, tshuaj methionine thiab tsos mob kom zoo.

Tus nqi ntawm Fervex yam tsis muaj suab thaj (8 pcs. Ib pob) muaj li ntawm 270 txog 600 rubles. Tus nqi ntawm Teraflu hmoov nyob ntawm seb muaj pes tsawg leej: 4 pcs. - los ntawm 200 p., 10 pcs. - 380 rubles.

Daim vis dis aus hauv tsab xov xwm no qhia cov ncauj lus kom ntxaws qhia txog kev kho mob khaub thuas rau ntshav qab zib.