Koob tshuaj ntau ntxiv thiab kev tswj hwm

Chlorpropamide (Chlorpropamidum)

N- (para-Chlorobenzenesulfonyl) -N - propylurea.
Dawb crystalline hmoov; tsw ntxhiab thiab mov. Nws yog xyaum insoluble hauv cawv, benzene, acetone.
Tus qauv nyob ze rau butamide, sib txawv ntawm cov tom kawg hauv qhov ntawd hauv txoj haujlwm para ntawm benzene nucleus nws muaj Cl atom hloov pawg CH3 thiab hloov pawg butyl (C 4 H 9) ntawm N 'nws muaj cov pab pawg propyl (C 3 H 7).

Sab sij huam

Kev tsis haum tshuaj, leukopenia (txo qis ntawm leukocytes hauv cov ntshav), thrombocytopenia (ua kom cov ntshav plasmaets tsawg nyob hauv ntshav), agranulocytosis (txo qis ntau ntau ntawm cov granulocytes hauv cov ntshav), raws plab (raws plab), mob cholestatic daj ntseg ib ntus (mob rau ntawm daim tawv nqaij thiab cov leeg). stagnation ntawm cov kua tsib hauv cov pob txha ua ke).

Cov Yuav Tsum Muaj

Precomatous (tsis nco qab tsis nco qab - lub sijhawm pib ntawm kev txhim kho tsis nco qab, ua cim los ntawm kev saib xyuas qhov mob thiab qhov mob tsis haum) thiab tsis nco qab (ua tiav tsis nco qab, ua rau tsis muaj lub cev tag nrho tsis cuam tshuam rau sab nraud stimuli) tej yam kev mob, ketoacidosis (acidification vim muaj ntau cov ntsiab lus ntawm ketone lub cev hauv cov ntshav - nruab nrab cov khoom lag luam hauv lub cev), menyuam yaus thiab tub ntxhais hluas, cev xeeb tub thiab lactation, mob sib kis ceev, lub raum tsis ua haujlwm, mob leukopenia, thrombocyte thiab granulocytopenia (lub siab kev txo qis hauv platelets thiab granulocytes hauv cov ntshav), kev phais mob, kev tsis haum rau sulfonamides.
Kev tsis pom tseeb contraindications yog jaundice thiab ua rau lub siab ua haujlwm tsis zoo.

Chlorpropamide - cov yam ntxwv thiab cov yam ntxwv ntawm kev thov

Txog kev kho mob pob qij txha, peb cov neeg nyeem tau siv DiabeNot siv tau zoo. Pom qhov nrov ntawm cov khoom no, peb tau txiav txim siab muab nws rau koj kom txaus siab.

Txoj kev kho rau hom 2 mob ntshav qab zib mellitus koom nrog kev tswj hwm cov ntshav qab zib cov tshuaj ntawm cov pab pawg sib txawv.

Cov no suav nrog sulfonylurea derivatives.

Ib tus sawv cev ntawm pawg no yog chlorpopamide.

Cov ntaub ntawv dav dav txog cov tshuaj

Chlorpropamide yog cov tshuaj nquag ua haujlwm uas yog los ntawm tiam 1 tiam sulfonylurea derivatives. Nws pharmacological pawg yog hypoglycemic hluavtaws tus neeg sawv cev. Chlorpropamide tsis yog soluble hauv dej, tab sis, ntawm qhov tsis tooj, yog soluble hauv cawv.

Tsis zoo li lwm tiam ntawm sulfonylurea derivatives, chlorpropamide ua haujlwm sai. Yuav kom ua tiav qib siab ntawm glycemia, nws yog siv rau hauv cov tshuaj loj.

Kev phiv los ntawm kev noj cov tshuaj muaj peev xwm tshaj tawm piv nrog Glibenclamide thiab lwm tus neeg sawv cev ntawm tiam 2. Pib siv nrog cov tshuaj hormone (insulin) tsis txaus thiab ua rau cov nqaij mos raug tshem tawm qis. Kev kho mob nrog chlorpropamide muaj cov nyhuv hauv cov neeg mob uas muaj ntshav qab zib ib feem insipidus thiab / lossis muaj ntshav qab zib hom 2.

Chlorpropamide yog cov tshuaj lub npe rau cov tshuaj. Nws ua cov hauv paus ntawm cov tshuaj (yog ib yam khoom ua haujlwm). Muaj nyob hauv ntsiav tshuaj.

Pharmacological kev txiav txim

Cov tshuaj muaj cov nyhuv hypoglycemic. Cov tshuaj khi rau cov kab mob potassium, txhawb kev ua haujlwm ntawm cov kua dej. Hauv cov ntaub so ntswg thiab cov plab hnyuv siab raum nqus tau los ntawm cov tshuaj insulin, tus naj npawb ntawm cov tshuaj hormones nce ntxiv.

Nyob rau hauv muaj cov endogenous insulin, cov piam thaj txo qis. Nws muaj cov kev ua haujlwm antidiuretic. Vim kev zais lub cev ntawm insulin, qhov hnyav nce tshwm sim.

Tiv thaiv glycemia yog me ntsis tso ntshav qab zib. Chlorpropamide, zoo li lwm yam sulfonylureas, ua rau muaj kev pheej hmoo ntawm hypoglycemia, tab sis rau qee yam tsawg dua.

Thaum ua ke nrog lwm tus kab mob hypoglycemic (biguanides, thiazolidinediones, pom kev sib cuam tshuam nrog lwm cov tshuaj), qhov ntau npaum ntawm cov tom kawg yog me ntsis txo.

Cov Tshuaj Pharmacokinetics

Tom qab nkag mus rau hauv lub plab zom mov, chlorpropamide zoo rau kev nqus. Tom qab ib teev, cov tshuaj muaj nyob rau hauv cov ntshav, nws lub siab tshaj plaws - tom qab 2-4 teev.Qhov khoom siv tshuaj yog metabolized hauv lub siab. Plasma protein khi> 90%.

Cov yeeb tshuaj ua thoob plaws ib hnub nyob rau hauv cov ntaub ntawv ntawm kev siv ib zaug. Qhov kev tshem tawm ib nrab-lub neej yog txog 36 teev. Nws yog tawm hauv feem ntau hauv cov zis (txog li 90%).

Kev taw qhia thiab contraindications

Kev qhia rau kev siv yog tsis muaj ntshav qab zib-insulin-mob ntshav qab zib, thiab ntshav qab zib insipidus. Chlorpropamide tau raug sau tseg rau hauv qhov xwm txheej uas kev noj zaub mov noj, kev tawm dag zog tsis tau coj cov txiaj ntsig kom raug ntawm kev kho qhov ntsuas.

Ntawm cov contraindications rau kev siv tshuaj muaj xws li:

• hypersensitivity rau chlorpropamide,
• Yam 1 ntshav qab zib
• hypersensitivity rau lwm sulfonylureas,
• metabolism nrog ib qho kev xav tau ntawm acidosis,
• cov thyroid pathology,
• ketoacidosis
• mob siab thiab mob raum tsis ua hauj lwm,
• mob kis yooj yim
• cev xeeb tub / lactation,
• poj koob yawm txwv thiab rau leej twg
• cov me nyuam muaj hnub nyoog
• pheej rov qab tsis ua haujlwm ntawm cov tshuaj chlorpropamide,
• tej yam kev mob tom qab kuaj kab mob.

Tsuas tshuaj thiab tswj hwm

Cov koob tshuaj tau teeb tsa los ntawm tus kws kho mob raws li cov chav kawm mob ntshav qab zib thiab kev nyem ntawm glycemia. Thaum ua tiav cov nyiaj raug mob ruaj khov hauv tus neeg mob, nws tuaj yeem txo qis. Raws li txoj cai, nrog hom 2 ntshav qab zib, qhov ib txwm ntsib yog 250-500 mg. Nrog ntshav qab zib insipidus - 125 mg ib hnub twg. Thaum pauv mus rau lwm cov tshuaj, yuav tsum tau kho ntau npaum li cas.

Cov lus qhia rau kev siv chlorpropamide qhia tias kev siv tshuaj li ib nrab ib teev ua ntej noj mov. Nws yog ib qho tseem ceeb kom haus nws ntawm ib zaug. Yog tias qhov tshuaj muab rau tsawg dua 2 ntsiav tshuaj, ces qhov kev txais tos yuav siv sijhawm sawv ntxov.

Video los ntawm cov kws tshaj lij mob ntshav qab zib thiab yuav kho nws li cas:

Daim ntawv thov nta

Ua ntej npaj kev xeeb tub, koj yuav tsum tso tseg chlorpropamide. Kev tswj ntshav qab zib hom 2 nrog insulin yog suav tias yog kev kho mob zoo tshaj plaws. Thaum lub sij hawm lactation, lawv ua raws li cov ntsiab cai ib yam.

Hloov mus rau cov tshuaj yog tsim los ntawm ib nrab ntsiav tshuaj hauv ib hnub, tom qab ntawd nws yog tshuaj rau thawj lub ntsiav tshuaj. Cov neeg mob uas lub raum / lub cev tsis ua haujlwm zoo yuav tsum tau txhaj koob tshuaj. Thaum sau daim ntawv noj ntau npaum li cas ntawm cov tshuaj rau cov neeg laus, lawv lub hnub nyoog tau coj mus rau hauv tus account.

Thaum them nyiaj rau tus kab mob, yuav tsum tau txo tshuaj ntau ntau. Kev kho kuj tseem ua tiav nrog kev hloov pauv ntawm lub cev nyhav, thauj khoom, hloov mus rau lwm lub sijhawm.

Vim tias tsis muaj cov ntaub ntawv hais txog kev nyab xeeb ntawm kev siv, cov tshuaj tsis tau sau tseg rau cov menyuam yaus. Yog tias muaj kev raug mob, ua ntej / tom qab ua haujlwm, thaum lub sijhawm sib kis cov neeg mob, tus neeg mob hloov mus rau insulin ib ntus.

Tsis txhob siv nrog Bozetan. Muaj cov ntaub ntawv pov thawj tias nws cuam tshuam rau cov neeg mob uas tau txais chlorpropamide. Lawv tau sau tseg tias qhov nce hauv cov kabmob hepatic (enzymes). Raws li lub zog ntawm ob qho tshuaj, lub tshuab ntawm kev nthuav dav ntawm cov kua tsib kua qaub los ntawm cov hlwb poob qis. Qhov no entails lawv cov tsub zuj zuj, uas ua rau kom muaj kev cuam tshuam.

Kev cuam tshuam nrog lwm yam tshuaj

Nrog rau kev siv tib txhij los ntawm chlorpropamide thiab lwm yam tshuaj, nws cov nyhuv yuav txo lossis nce ntxiv. Yuav tsum tau sab laj ua ntej yuav noj lwm yam tshuaj.

Ua tshuaj txiav txim tshwm sim thaum coadministered nrog insulin, lwm yam hypoglycemic tshuaj, biguanides, coumarin derivatives, phenylbutazone, tshuaj tetracycline, Mao inhibitors, fibrates, salicylates, miconazole, streroidami, txiv neej cov tshuaj hormones, cytostatics, sulfonamides, quinolone derivatives, clofibrate, sulfinpyrazone.

Cov tshuaj nram qab no ua rau cov tshuaj chlorpropamide ua kom tsis tshua muaj zog: barbiturates, diuretics, adrenostimulants, estrogens, ntsiav tshuaj tiv thaiv kab mob, koob tshuaj ntau ntawm nicotinic acid, diazoxide, thyroid hormones, phenytoin, glucocorticosteroids, sympathomimetics, phenothiazine derivatives, Acetazolamide.

Chlorpropamide yog ib tus neeg sawv cev hypoglycemic uas yog hais txog tiam 1 tiam sulfonylurea derivatives. Piv nrog rau nws cov thwjtim, nws muaj suab thaj ua rau qis dua thiab muaj cov teebmeem tshwm sim ntau dua. Tam sim no, cov tshuaj yog tsis siv.

Tshuaj txwv tswj ntshav qab zib

Qee txoj kev tuaj yeem cuam tshuam txog ntshav qab zib. Kawm paub kev tswj tsis pub muaj menyuam siv rau cov muaj ntshav qab zib.

Tus poj niam muaj ntshav qab zib yuav tsum ntsib qhov teeb meem tib yam uas cov poj niam feem ntau ntsib, xws li kev xaiv tswj tsis pub muaj menyuam. Txawm li cas los xij, tsis zoo li cov poj niam uas tsis muaj ntshav qab zib, nws yuav tsum coj mus rau hauv seb qhov kev txiav txim siab twg nws xaiv yuav cuam tshuam nws cov ntshav qab zib.

Mob ntshav qab zib thiab tshuaj txwv

Sij hawm dhau los, cov tshuaj txwv tsis pub siv rau cov poj niam muaj ntshav qab zib vim muaj kev hloov hauv cov tshuaj hormones uas kho tuaj yeem ua rau. Cov tshuaj hormones ntau heev tuaj yeem muaj qhov cuam tshuam zoo rau cov ntshav qab zib, uas ua rau nws nyuaj rau tus poj niam los tswj lawv cov ntshav qab zib. Txawm li cas los xij, kev tshawb fawb rau cov txheej txheem tsim tshiab tau ua rau cov tshuaj hormones ntau dua ua ke. Cov tshuaj noj tshiab, xws li kev npaj ntawm lub qhov ncauj Jess, muaj kev nyab xeeb rau ntau tus poj niam, tsis tsuas yog muaj ntshav qab zib. Yog tias koj tsis muaj kev paub txog kev siv tshuaj tiv thaiv no, nyeem tus kws kho mob tshuaj xyuas txog ntsiav tshuaj. Cov poj niam muaj ntshav qab zib uas txiav txim siab siv tshuaj tiv thaiv kev xeeb tub yuav tsum noj tsawg kawg nkaus kom txo cov nyhuv ntawm cov tshuaj tiv thaiv ntshav qab zib.

Tab sis, cov poj niam noj tshuaj tswj tsis pub muaj menyuam yuav tsum nco ntsoov tias tseem muaj kev pheej hmoo ntawm myocardial infarction lossis mob hlab ntsha tawg rau cov poj niam siv txoj kev tiv thaiv kom tsis txhob muaj menyuam yaus no. Txij li cov neeg muaj ntshav qab zib kuj tseem muaj kev pheej hmoo mob plawv heev, cov poj niam yuav tsum sab laj nrog kws kho mob.

Mob ntshav qab zib thiab lwm yam tshuaj tiv thaiv hormonal

Tshuaj tiv thaiv tsis pub sib deev tsis yog tib txoj kev los siv cov tshuaj hormones los tiv thaiv kev xeeb tub. Kuj tseem muaj kev txhaj tshuaj, kev cog hniav, ib ncig thiab ib ncig.

Cov koob tshuaj tau dhau los ua qhov kev xaiv nrov vim tias ib qho kev txhaj tshuaj rau ntawm Diot medroxyprogesterone acetate (Depo-Provera) tuaj yeem tiv thaiv kev xeeb tub mus txog peb lub hlis. Siv txoj hau kev no, cov poj niam yuav tsum xav txog kev tswj tsis pub muaj plaub zaug nyob rau ib xyoos. Txawm li cas los xij, vim tias kev txhaj tshuaj siv cov tshuaj hormone progestin, nws yuav muaj kev phiv xws li hnyav dua, nce plaub hau tsis zoo, kiv taub hau, mob taub hau, thiab ntxhov siab.

Yog tias koj tsis nyiam txhaj tshuaj nyob rau txhua txhua peb lub hlis, koj tuaj yeem sim siv cov khoom cog tswj kev xeeb tub. Qhov no yog cov yas yas me me-cov nplaum uas haum rau hauv qab daim tawv nqaij ntawm koj caj npab. Thaum cog hniav ntawv nyob rau hauv qhov chaw, nws tso progestin, tib qho tshuaj hormones ib yam li kev txhaj tshuaj.

Lwm cov cuab yeej tshiab muaj nyob hauv pawg tiv thaiv yog lub nplhaib ntawm qhov paum, uas hnav rau 21 hnub. Lub nplhaib no tau muab tso rau hauv thaj av sab sauv ntawm qhov chaw mos, thaum nws nyob hauv qhov chaw, koj tsis hnov ​​nws. Lub nplhaib muab khoom tsis tsuas yog cov tshuaj progestin, tab sis kuj tseem muaj estrogen, uas txhais tau tias cov poj niam uas siv nws yuav muaj kev phiv uas zoo sib xws rau cov ntsiav tshuaj tiv thaiv.

Thaum kawg, muaj tus cwj mem los tiv thaiv. Zoo li lwm cov tshuaj plasters, piv txwv, uas pab koj txiav luam yeeb, thaj ua rau lub ntsej muag ua haujlwm thaum thov rau ntawm daim tawv nqaij. Lub thaj tso cov tshuaj estrogen thiab progestin hauv ib lub lis piam, thiab tom qab ntawd nws hloov nrog tus tshiab, qhov no ua rau tag nrho ntawm peb lub lis piam sib law liag. Daim npog tsis hnav rau plaub lub lim tiam (thaum lub sijhawm coj khaub ncaws), thiab tom qab ntawd lub voj voog rov ua dua. Ib zaug ntxiv, cov kev mob tshwm sim tuaj yeem zoo xws li kev tswj kom tsis pub muaj menyuam hauv plab lossis thaj chaw hauv lub paum, ntxiv rau tej zaum yuav muaj qee qhov tawv nqaij nyob rau thaj tsam ntawm daim tawv nqaij uas koj siv qhov thaj.

Zoo li tshuaj tswj tsis pub muaj menyuam, lwm yam tshuaj tiv thaiv kev xeeb tub tuaj yeem cuam tshuam koj cov ntshav qab zib. Yog tias koj txiav txim siab siv ib txoj hauv kev no, koj yuav tau kho qhov ntau thiab tsawg ntawm koj cov tshuaj kho ntshav qab zib.

Mob ntshav qab zib thiab cov leeg ntshav

Intrauterine devices (IUDs) yog cov khoom siv tso rau hauv lub tsev menyuam. Lub IUD tseem nyob hauv qhov chaw rau qee lub sijhawm kom txog thaum tus kws kho mob tshem tawm. Rau cov laj thawj uas cov kws kho mob tsis nkag siab meej, IUD txwv tsis pub lub qe qe xeeb menyuam los rau hauv lub tsev menyuam thiab yog li pab tiv thaiv kev xeeb tub. Txawm hais tias IUD yog txoj hauv kev muaj txiaj ntsig ntawm kev tswj tsis pub muaj menyuam, ib qho kev pheej hmoo ntawm kev siv lub cuab yeej yog kev kis mob rau hauv tsev menyuam.

Cov poj niam uas mob ntshav qab zib twb muaj feem ntau yuav kis mob tau vim lawv muaj mob, yog li hom kev tswj tsis pub menyuam no yuav tsis yog qhov kev xaiv zoo tshaj plaws yog tias koj muaj ntshav qab zib.

Mob ntshav qab zib thiab cov txheej txheem thaiv kev tiv thaiv tsis pub muaj menyuam

Nrog kev txhawj xeeb txog kab mob kis los ntawm kev sib daj sib dee, txoj hauv kev thaiv tau nrov zuj zus tuaj ntawm cov poj niam. Los ntawm kev tiv thaiv cov phev kom ncav cuag lub tsev me nyuam, kev pheej hmoo ntawm cev xeeb tub, nrog rau kev kis tus kab mob, yog txo qis.

Rau feem ntau ntawm cov poj niam, txoj kev thaiv kev tuaj yeem yog txoj hauv kev tiv thaiv kom zoo, thiab cov hnab looj qau thiab cov paum ntawm qhov chaw mos tsis cuam tshuam rau cov ntshav qab zib. Nws yog ib qho tseem ceeb, txawm li cas los xij, kom nkag siab tias cov txheej txheem thaiv kev tiv thaiv tau muaj kev siv ntau dua kev puas tsuaj ntau dua cov ntsiav tshuaj thiab yuav tsum siv kom raug, nrog rau txhua qhov kev sib deev. Ntxiv rau, cov poj niam uas muaj ntshav qab zib yuav muaj kev pheej hmoo siab los ntawm kev muaj mob ua paug thaum siv lub diaphragm.

Mob ntshav qab zib thiab kom tsis muaj menyuam

Thaum kawg, kab tias qhov kev nyab xeeb tshaj plaws muaj txiaj ntsig zoo, ua kom tsis muaj menyuam yog siv txoj kev phais hu ua tubal ligation. Qhov no yog, txawm li cas los xij, ib hom kev ruaj khov mus ib txhis yog tias tus poj niam tab tom raug phais. Qhov kev ntseeg tau ntawm hom no yog qhov zoo tshaj plaws Pro, thiab qhov tseeb tias nws tsis tu ncua tuaj yeem "tawm tsam" yog tias koj tsis 100 feem pua ​​paub tseeb tias koj tsis xav tau menyuam yaus.

Lwm qhov hauv kev pom zoo ntawm cov qauv no rau cov poj niam uas muaj ntshav qab zib yog tias qhov tsis muaj menyuam tsis cuam tshuam txog ntshav qab zib cov ntshav ntawm tus poj niam. Txawm li cas los xij, kev khiav haujlwm tsis yog yam tsis muaj kev phom sij, suav nrog kev kis mob thiab lwm yam teebmeem.

Txawm hais tias koj xaiv, txoj kev siv tiv thaiv tsis pub lwm tus paub yog qhov tseem ceeb rau cov poj niam muaj ntshav qab zib, vim tias kev xeeb tub tsis tau ua tiav yog txuam nrog kev pheej hmoo rau kev noj qab haus huv ntawm leej niam thiab menyuam. Ua lub luag haujlwm rau koj txoj kev noj qab haus huv ua rau koj nyob hauv lub rooj tsav tsheb.

Txog kev kho mob pob qij txha, peb cov neeg nyeem tau siv DiabeNot siv tau zoo. Pom qhov nrov ntawm cov khoom no, peb tau txiav txim siab muab nws rau koj kom txaus siab.

Thov

Cov koob tshuaj tau teeb tsa ib tus zuj zus, coj mus rau hauv tus lej ntsuas ntawm glycemia thiab glucosuria. Thawj qhov tshuaj yog 250 mg / hnub, rau cov neeg laus laus - 100-125 mg / hnub, lub sijhawm siv yog 3-5 hnub. Tom qab ntawd, nyob ntawm cov nyhuv, qhov koob tshuaj yog maj mam txo lossis nce ntau zog los ntawm 50-125 mg nrog qhov luv ntawm 3-5 hnub. Qhov nyiaj pab ntau tshaj txhua hnub yog 500 mg.

Qhov nruab nrab cov tshuaj txij nkawm yog 100-500 mg / hnub, nyob ntawm tus mob ntawm tus neeg mob, qhov ntau zaus ntawm kev tswj hwm yog 1 r / hnub thaum noj tshais. Thaum hloov lwm yam kab mob hypoglycemic nrog chlorpropamide, cov tshuaj uas siv yav dhau los yuav tsum tau txiav tawm thiab chlorpropamide yuav tsum tau sau tseg nyob rau hauv ib koob ntawm 250 mg / hnub.

Lub sijhawm ntev siv cov tshuaj yuav ua rau txo qis rhiab heev rau cov neeg sawv cev ntawm qhov ncauj hypoglycemic.Thaum cov tshuaj chlorpropamide ntxiv rau kev kho mob insulin yav dhau los (hauv qhov xwm txheej txhua hnub cov tshuaj insulin tsis pub tshaj 40 units), qhov tshuaj ntawm cov insulin feem ntau txo qis 50%.

Sab sij huam

- Kev muab cov ntshav qog ua ntshav nce siab ntau yam, txog thaum hnov ​​qab,
- Mob plab zom mov (tsis xeev siab, ntuav, zoo nkaus hauv lub plab),
- daim tawv nqaij AR (liab, urticaria),
- qee zaum - leukopenia, agranulocytosis,
- tsis tshua muaj tshwm sim - muaj ntsej muag daj ntseg, txhaws qa ntshav, mob ntshav liab txaus.

Yuav siv li cas: noj ntau thiab hom tshuaj kho

Sab hauv. Hauv cov ntshav qab zib mob hnyav nrog mob hyperglycemia thiab glucosuria, lawv pib nrog 0.5 g ib hnub ib zaug, thaum sawv ntxov, 30 feeb ua ntej noj mov.

Hauv cov mob ntshav qab zib me me - los ntawm koob tshuaj 0.25 g, hauv qhov tsis muaj tshwm sim hauv 1 lub lis piam, qhov koob tshuaj tau nce rau 0.5 g, thiab qee qhov xwm txheej rau 0.75 g. Nrog rau qhov ua haujlwm ntawm glycemia thiab tshem tawm glucosuria, qhov koob tshuaj yog maj mam txo los ntawm 0.125 g txhua 2 lub lis piam. Hauv qhov tsis muaj ntawm cov nyhuv ntawm koob ntawm 0.75 g, kev tswj hwm ntxiv yog impractical.

Nrog ntshav qab zib insipidus - 0.1-0.15 g / hnub.

Cov lus qhia tshwj xeeb

Kev tshuaj xyuas kev yoo cov ntshav sai thiab tom qab noj glycosylated Hb, glycemia thiab glucosuria niaj hnub tsim nyog.

Rau kev raug mob, kev phais mob, kev kis kab mob, thaum cev xeeb tub, hloov mus rau ib ntus ntawm tus neeg mob mus rau insulin.

Cov neeg mob yuav tsum tau ceeb toom txog qhov ua tau kom muaj kev tiv thaiv hypoglycemic, tshwj xeeb tshaj yog thaum sib kis lossis lub caij noj tsis txaus.

Cov tsos mob ntawm cov ntshav qog ntshav yuav tawm los yog qog ntawm cov neeg laus uas muaj cov leeg mob hlwb lossis tib lub sijhawm tau txais beta-blockers, clonidine, reserpine, guanethidine lossis lwm yam sympatholytics.

Yog tias nws yuav tsum tau hloov tus neeg mob los ntawm kev kho mob insulin mus rau kev tswj hwm tshuaj hauv qhov ncauj ntawm chlorpropamide, kev txhaj tshuaj insulin tuaj yeem nres sai, thiab yog tias tus neeg mob tau txais ntau tshaj 40 PIECES / hnub, ces kev kho mob nrog chlorpropamide tuaj yeem pib nrog 50% txo qis ntawm cov tshuaj insulin hauv thawj ob peb hnub.

Thaum them nyiaj rau ntshav qab zib mellitus, cov tshuaj insulin rhiab heev (muaj peev xwm txo qis qhov xav tau ntawm cov tshuaj).

Koob tshuaj hloov kho yog ua nrog kev hloov pauv hauv tus neeg mob lub cev qhov hnyav, kev ua neej, vim yog txoj kev pheej hmoo ntawm cov ntshav qog ntshav nce siab.

Thaum lub sijhawm kho mob, yuav tsum tau saib xyuas thaum tsav tsheb thiab koom nrog lwm yam kev phom sij uas yuav tsum muaj kev mloog zoo thiab ceev ntawm cov kev tiv thaiv psychomotor.

Cov lus nug, lus teb, tshuaj xyuas tshuaj Chlorpropamide

Cov ntaub ntawv muab yog npaj rau kev kho mob thiab kws tshaj lij. Cov ntaub ntawv meej tshaj plaws txog cov tshuaj muaj nyob rau hauv cov lus qhia uas tuaj nrog cov neeg ua khoom ntim. Tsis muaj cov ntaub ntawv tso tawm rau ntawm no lossis lwm nplooj ntawv ntawm peb lub xaib tuaj yeem hloov chaw rau qhov tsis txaus siab tus kheej rau tus kws tshaj lij.

Kws Tshuaj

Tsim kho kev tsim cov tshuaj insulin los ntawm pancreatic beta hlwb thiab nce tus naj npawb ntawm insulin receptors hauv phiaj plab hnyuv siab raum. Nws muaj cov kev ua haujlwm antidiuretic.

Nws yog zoo nqus los ntawm lub plab zom mov, nws yog kuaj pom hauv cov ntshav hauv thawj teev tom qab kev tswj hwm. C_max tiav nyob rau hauv 2-4 teev_1/2 - 36 teev. Nws raug tawm los ntawm lub raum (80-90% ntawm qhov koob tshuaj) rau 96 teev, suav nrog 20-30% tsis pauv hlo li. Kev siv tshuaj hypoglycemic tom qab siv ib zaug li 24 xuab moos.

Noj ntau dhau

Kev Kho Mob: nrog cov ntshav qog ntshav qab zib tsawg - kev noj ntawm cov piam thaj sab hauv, kev hloov kho tshuaj lossis zaub mov noj. Hauv daim ntawv loj heev (tsis tshua muaj) nrog rau coma thiab mob huam - qhia txog 50% cov ntshav qabzib nyob rau hauv thiab cov ntshav ntawm 10% kua nplaum tov (kom tswj tau cov ntshav qabzib siab tshaj 100 mg / dl), ua tib zoo saib xyuas ntshav qabzib ntau ntau rau 24– 48 h

Cov npe lag luam

Lub vev xaib ntawm lub tuam txhab radar. Lub encyclopedia tseem ceeb ntawm cov tshuaj thiab cov khoom muag ntawm cov khw muag tshuaj assortment ntawm Lavxias Internet. Daim ntawv teev cov tshuaj Rlsnet.ru muab cov neeg siv kev nkag mus rau cov lus qhia, tus nqi thiab cov lus piav qhia txog tshuaj, khoom noj khoom haus, khoom siv kho mob, khoom siv kho mob thiab lwm yam khoom lag luam. Daim ntawv qhia pharmacological suav nrog cov ntaub ntawv ntawm kev sib xyaw thiab daim ntawv tso tawm, kev nqis tes ua pharmacological, kev taw qhia rau kev siv, contraindications, kev phiv tshuaj, kev cuam tshuam tshuaj, hom kev siv tshuaj, cov tuam txhab tshuaj. Daim ntawv qhia cov tshuaj muaj nqi rau tshuaj thiab cov khoom lag luam tshuaj hauv Moscow thiab lwm lub nroog Lavxias.

Nws yog txwv tsis pub xa, theej, tshaj tawm cov ntaub ntawv yam tsis tau txais kev tso cai los ntawm RLS-Patent LLC.
Thaum hais cov ntaub ntawv xov xwm luam tawm nyob rau ntawm nplooj ntawv ntawm lub xaib www.rlsnet.ru, qhov txuas mus rau qhov chaw ntawm cov ntaub ntawv xav tau.

Ntau ntau yam nthuav

Qoob loo.

Kev ua lag luam siv cov ntaub ntawv tsis raug tso cai.

Cov ntaub ntawv yog npaj rau cov kws kho mob.