Thiogamma analogues
Thiogamma yog ib qho tshuaj tiv thaiv kab mob antioxidant thiab tshuaj metabolic uas ua rau kev hloov pauv ntawm cov carbohydrate thiab lipid.
Cov tshuaj nquag ntawm cov tshuaj yog thioctic (alpha-lipoic) acid. Nws yog ib qho tshuaj antioxidant endogenous uas khi dawb. Thioctic acid yog tsim nyob rau hauv lub cev thaum lub zog oxidative decarboxylation ntawm alpha-keto acids.
Thioctic acid tswj kev ua kom muaj carbohydrate thiab lipid metabolism, txhim kho daim siab ua haujlwm thiab txhawb cov metabolism hauv cov roj cholesterol. Nws muaj cov tshuaj tiv thaiv hypolipidemic, hypoglycemic, hepatoprotective thiab hypocholesterolemic effect. Txhawb nqa cov khoom noj khoom haus zoo ntawm neurons.
Alpha-lipoic acid pab txo cov ntshav qabzib, nce qhov nce ntawm glycogen hauv daim siab thiab kov yeej cov tshuaj insulin. Los ntawm cov txheej txheem ntawm kev nqis tes ua, nws nyob ze rau cov vitamins ntawm pab pawg B.
Cov kev tshawb fawb txog cov nas nrog streptozotocin-vim cov ntshav qab zib tau pom tias thioctic acid txo kev tsim cov khoom tom kawg glycation, txhim kho endoneural ntshav txaus, thiab nce qib ntawm physiological antioxidants xws li glutathione. Cov ntaub ntawv sim ua piv txwv qhia tau tias thioctic acid txhim kho kev ua haujlwm peripheral neuron.
Qhov no siv rau cov kev xav hnov mob hauv kev mob ntshav qab zib, xws li dysesthesia, paresthesia (hlawv, mob, nkag, txo qis rhiab). Cov kev cuam tshuam tau lees paub los ntawm cov kws kuaj mob sib kis tau ua nyob rau xyoo 1995.
Cov ntawv tso tawm cov tshuaj:
- Ntsiav tshuaj - 600 mg ntawm cov tshuaj nyob hauv txhua,
- Ib qho kev daws teeb meem rau kev tswj hwm ntawm tsoomfwv ntawm 3%, ampoules ntawm 20 ml (hauv 1 ampoule 600 mg ntawm cov tshuaj yeeb dej caw),
- Thiogamma-turbo - kev daws teeb meem rau cov niam txiv kev ua haujlwm 1.2%, 50 ml vials (hauv 1 lub raj mis 600 mg ntawm cov tshuaj nquag).
Kev ntsuas rau siv
Dab tsi pab Tiogamma? Qhia cov tshuaj hauv cov kis hauv qab no:
- Cov kab mob siab ua rog (rog daim siab ua haujlwm),
- Hyperlipidemia tsis paub meej keeb kwm (cov ntshav muaj roj ntau)
- Daj yuv lom (mob rau daim siab ua paug),
- Daim siab ua haujlwm
- Cawv cawv thiab nws lub txim,
- Kab mob siab ntawm ib yam keeb kwm,
- Kab mob siab
- Cov mob ua paug rau daim siab.
Cov lus qhia rau kev siv Thiogamma, noj ntau npaum li cas
Cov ntsiav tshuaj tau noj ntawm qhov ncauj, ntawm lub plab tas, ntxuav cia nrog kua me me.
Qhov koob tshuaj pom zoo yog 1 ntsiav tshuaj ntawm Tiogamma 600 mg 1 zaug ib hnub. Lub sijhawm kho yog nyob ntawm tus mob hnyav thiab ntau li 30 mus rau 60 hnub.
Hauv lub xyoo, chav kawm ntawm kev kho tuaj yeem rov ua dua 2-3 zaug.
Txhaj tshuaj
Cov tshuaj yog muab rau iv hauv ib koob tshuaj 600 mg / hnub (1 amp. Mloog zoo rau kev npaj ntawm kev daws rau Txoj kev lis ntshav ntawm 30 mg / ml lossis 1 lub raj ntawm ib qho kev daws rau infusion ntawm 12 mg / ml).
Thaum pib ntawm chav kawm ntawm kev kho mob, nws raug nquahu kom siv tshuaj rau iv rau 2-4 lub lis piam. Tom qab ntawd koj tuaj yeem txuas ntxiv noj cov tshuaj sab hauv ntawm koob tshuaj 300-600 mg / hnub.
Thaum ua qhov kev ua haujlwm ntawm qhov mob ntshav, tshuaj yuav tsum tau maj mam muab qeeb, ntawm tus nqi tsis ntau tshaj 50 mg / min (uas yog sib npaug rau 1.7 ml ntawm mloog zoo rau kev npaj ntawm kev daws rau Txoj kev lis ntshav ntawm 30 mg / ml).
Npaj ib qho kev daws teeb meem - cov ntsiab lus ntawm ib lub ampoule ntawm qhov muaj zog yuav tsum tov nrog 50-250 ml ntawm 0.9% sodium chloride tov. Lub raj mis nrog cov tshuaj daws npaj txhij tau nrog cov teeb meem tiv thaiv lub teeb, uas ua tiav nrog cov tshuaj. Cov tshuaj tiav tau tuaj yeem khaws cia rau tsis pub dhau 6 teev.
Yog tias txoj kev daws teeb meem infusion npaj siv, lub raj mis tshuaj tau tawm hauv lub thawv thiab tam sim ntawd npog nrog lub teeb tsom-thaiv. Cov lus qhia yog ua ncaj qha los ntawm lub raj mis, maj mam - ntawm qhov ceev ntawm 1.7 ml / feeb.
Sab sij huam
Thiogamma tej zaum yuav cuam tshuam nrog cov kev mob tshwm sim hauv qab no:
Los ntawm lub plab zom mov: thaum noj tshuaj hauv - dyspepsia (suav nrog xeev siab, ntuav, kub siab).
- Los ntawm sab ntawm lub hauv nruab nrab cov hlab ntsha hauv lub cev: tsis tshua muaj (tom qab iv kev tswj hwm) - kev nrhav, daim ntawv pov thawj kawm tiav, nrog kev tswj hwm sai - nce siab intracranial siab (qhov pom ntawm lub siab ntawm qhov hnyav ntawm lub taub hau).
- Los ntawm cov ntshav kev sib xyaw ua ke: tsis tshua muaj (tom qab kev tswj hwm iv) - taw qhia cov ntshav hauv cov leeg nqaij, daim tawv nqaij, thrombocytopenia, hemorrhagic pob (purpura), thrombophlebitis.
- Los ntawm lub tshuab ua pa: nrog ceev ntawm / hauv kev qhia, ua pa nyuaj tau.
- Ua xua: urticaria, mauj tshuaj tiv thaiv (nce mus rau hauv kev nthuav dav ntawm anaphylactic kev poob siab).
- Lwm tus: hypoglycemia tuaj yeem tsim muaj (vim tias txhim kho cov piam thaj hauv siab).
Cov Yuav Tsum Muaj
Thiogamma yog contraindicated nyob rau hauv cov nram no:
- cov menyuam yaus thiab cov tub ntxhais hluas hnub nyoog qis dua 18 xyoo,
- cev xeeb tub lub sij hawm
- lactation lub sijhawm
- piam thaj-galactose malabsorption, lactase deficiency, cov roj ntsha tsis sib haum (rau cov ntsiav tshuaj),
- hypersensitivity rau lub ntsiab los yog txhawb cov tshuaj ntawm cov tshuaj.
Tawm tsam keeb kwm yav dhau los ntawm kev siv yeeb tshuaj, dej cawv tsis tuaj yeem nqa, txij li nyob rau hauv kev cuam tshuam ntawm ethanol, qhov ntxim nyiam ntawm kev tsim muaj mob hnyav los ntawm cov leeg hlwb thiab cov hnyuv nce ntxiv.
Thiogamma analogs, tus nqi hauv cov chaw muag tshuaj
Yog tias tsim nyog, koj tuaj yeem hloov Thiogamma nrog ib qho piv txwv ntawm cov tshuaj nquag - cov no yog cov tshuaj:
Thaum xaiv cov tshuaj analogues, nws yog ib qho tseem ceeb kom nkag siab tias cov lus qhia rau kev siv Tiogamma, tus nqi thiab tshuaj xyuas cov tshuaj uas muaj cov teebmeem zoo sib xws tsis siv. Nws yog ib qho tseem ceeb kom kws kho mob sab laj thiab tsis txhob hloov pauv cov tshuaj ywj siab.
Cov nqi hauv Moscow cov chaw muag tshuaj: Thiogamma daws 12 mg / ml 50 ml - los ntawm 197 txog 209 rubles. 600 mg ntsiav tshuaj 30 pcs. - los ntawm 793 txog 863 rubles.
Khaws tawm ntawm qhov ncav cuag cov menyuam yaus, tiv thaiv los ntawm lub teeb, ntawm qhov kub txog li 25 ° C. Txee lub neej yog 5 xyoos. Hauv cov tsev muag tshuaj, muaj cov ntawv sau tshuaj.
3 kev xyuas rau “Tiogamma”
Nws pab heev. Niam pheej haus cov tshuaj no 2 zaug ib xyoos. Tom qab siv nws, nws xav tau zoo dua!
Kuv tau muab qhov tshuaj mob me me nrog thiagia ntawm 14.00 thaum tav su, thiab thaum 24.00 tsaus ntuj ua rau lub siab poob rau 177 los ntawm 120. Kuv lub taub hau mob heev, Kuv xav tias nws yuav tawg. Qee yam coj los tso ntawm lub siab ntawm Corinfar thiab Kapoten. Kuv pom tau hais tias xws li tawm tsam rau tiag tiag u
Tus kws kho plawv tawm tswv yim lipoic acid rau nws tus tub, tab sis tsis yog hom tshuaj no.
Analogs hauv kev muaj pes tsawg leeg thiab qhia txog kev siv
| Npe | Nqe hauv Lavxias | Nqe hauv Ukraine |
|---|---|---|
| Alpha lipon alpha lipoic kua qaub | -- | 51 UAH |
| Berlition 300 Qhov Ncauj | -- | 272 UAH |
| Berlition 300 thioctic acid | 260 rub | 66 UAH |
| Dialipon thioctic acid | -- | 26 UAH |
| Espa lipon thioctic acid | 27 RUB | 29 UAH |
| Espa lipon 600 thioctic acid | -- | 255 UAH |
| Alpha Lipoic Acid Alpha Lipoic Acid Txhaws Los Ntawm Alpha Lipoic Acid | 165 rub | 235 UAH |
| Oktolipen | 285 rub | 360 UAH |
| Berlition 600 thioctic acid | 755 RUB | 14 UAH |
| Dialipon Turbo thioctic acid | -- | 45 UAH |
| Tio-Lipon - Novopharm thioctic acid | -- | -- |
| Thiogamma Turbo thioctic acid | -- | 103 UAH |
| Thioctacid thioctic acid | 37 RUB | 119 UAH |
| Kev soj ntsuam thioctic acid | 7 RUB | 700 UAH |
| Thioctacid BV thioctic acid | 113 rub | -- |
| Thiolipone thioctic acid | 306 rub | 246 UAH |
| Altiox thioctic acid | -- | -- |
| Thiocta thioctic acid | -- | -- |
Cov npe saum toj no ntawm cov yeeb tshuaj analogues, uas qhia Thiogamma hloov chaw, yog qhov tsim nyog tshaj plaws vim tias lawv muaj tib cov tshuaj sib luag thiab sib luag ua ke raws li kev taw qhia rau kev siv
Analogs los ntawm qhov taw qhia thiab cov qauv ntawm kev siv
| Npe | Nqe hauv Lavxias | Nqe hauv Ukraine |
|---|---|---|
| Lub Lipin | -- | 230 UAH |
| Maum Khub | 20 RUB | 15 UAH |
| Alder txiv hmab txiv ntoo | 47 rub | 6 UAH |
| Cov tshuaj placenta extract tib neeg cov txiv neej | 1685 RUB | 71 UAH |
| Chamomile paj Chamomile officinalis | 25 RUB | 7 UAH |
| Rowan txiv ntoo Rowan | 44 RUB | -- |
| Rosehip Syrup | 29 RUB | -- |
| Rosehip txiv hmab txiv ntoo fortified syrup | -- | -- |
| Lub duav Rose Hips | 30 RUB | 9 UAH |
| Beroz Immortelle xuab zeb, Hypericum perforatum, Chamomile | -- | 4 UAH |
| Bioglobin-U Bioglobin-U | -- | -- |
| Vitamin sau No. 2 Roob tshauv, Rosehip | -- | -- |
| Gastricumel Argentum nitricum, Acidum arsenicosum, Pulsatilla pratensis, Stryhnos nux-vomiсa, Carbo zaub ntsuab, Stibium sulfuratum nigrum | 334 txhwm | 46 UAH |
| Kev sib xyaw ntawm ntau cov tshuaj yeeb dej caw | -- | 12 UAH |
| Dalargin Biolik Dalargin | -- | -- |
| Dalargin-Farmsynthesis Dalargin | -- | 133 UAH |
| Detoxify ua ke nrog ntau cov tshuaj nquag | -- | 17 UAH |
| Cov me nyuam tshuaj yej nrog chamomile Altai officinalis, Blackberry, Peppermint, Plantain lanceolate, Medicinal chamomile, liab qab licorice, Hom thyme, Hom fennel, Hops | -- | -- |
| Pauv plab zom mov Hypericum perforatum, Calendula officinalis, Peppermint, Tshuaj chamomile, Yarrow | 35 txhuam | 6 UAH |
| Kalgan cinquefoil erect | -- | 9 UAH |
| Laminaria slani (hiav txwv kale) Laminaria | -- | -- |
| Lipin-Biolik lecithin | -- | 248 UAH |
| Moriamin Forte yog kev sib xyaw ntawm ntau cov khoom xyaw nquag | -- | 208 UAH |
| Kev Lag Luam Sib Tw buckthorn | -- | 13 UAH |
| Txo txuam nrog ntau cov tshuaj yeeb dej caw | -- | -- |
| Aronia chokeberry Aronia chokeberry | 68 rub | 16 UAH |
| Kev kho mob thiab kho cov khoom sau cia No. 1 Valerian officinalis, Stinging nettle, Peppermint, Sowing oats, Loj plantain, Chamomile, Chicory, Rosehip | -- | -- |
| Kev kho mob thiab kho mob sau cia No. 4 Hawthorn, Calendula officinalis, Flax zoo tib yam, Peppermint, Plantain loj, Chamomile, Yarrow, Hops | -- | -- |
| Hom phytogastrol, peppermint, lam chamomile, licorice liab qab, tsw ntxhiab tsw | 36 tshiav | 20 UAH |
| Celandine nyom Celandine zoo tib yam | 26 RUB | 5 UAH |
| Enkad biolik enkad | -- | -- |
| Mob ncauj plab | -- | -- |
| Aloe extract | -- | 20 UAH |
| Orfadine Nitizinone | -- | 42907 UAH |
| Kab npauj Miglustat | 155,000 RUB | 80 100 UAH |
| Kuvan Sapropertin | 34 300 rub | 35741 UAH |
| Actovegin | 26 RUB | 5 UAH |
| Apilak | 85 RUB | 26 UAH |
| Hematogen albumin dub zaub mov | 6 rub | 5 UAH |
| Elekasol Calendula officinalis, Chamomile officinalis, liab qab licorice, kev vam meej kev vam meej, tshuaj sage, Qws Eucalyptus | 56 tshiav | 9 UAH |
| Momordica compositum homeopathic potencies ntawm ntau yam tshuaj yeeb dej caw | -- | 182 UAH |
| Brewer lub poov xab | 70 RUB | -- |
| Plazmol extract ntawm muab ntshav | -- | 9 UAH |
| Raug tshuaj lom neeg Vitreous | 1700 RUB | 12 UAH |
| Ubiquinone compositum homeopathic potencies ntawm ntau yam tshuaj yeeb dej caw | 473 rub | 77 UAH |
| Galium Luj | -- | 28 UAH |
| Thyroididea Compositum homeopathic potencies ntawm ntau yam tshuaj yeeb dej caw | 3600 rub | 109 UAH |
| Cov hlwv dej uridine triacetate | -- | -- |
| Vistogard Uridine Triacetate | -- | -- |
Sib txawv muaj pes tsawg leeg, tuaj yeem ua ke nyob rau hauv kev taw qhia thiab cov qauv ntawm daim ntawv thov
| Npe | Nqe hauv Lavxias | Nqe hauv Ukraine |
|---|---|---|
| Immunofit Cua zoo tib yam, Elecampane siab, Leuzea safflower, Dandelion, liab qab licorice, Rosehip, Echinacea purpurea | -- | 15 UAH |
| Ectis Actinidia, Artichoke, Ascorbic Acid, Bromelain, Ginger, Inulin, Cranberry | -- | 103 UAH |
| Octamine Plus valine, isoleucine, leucine, lysine hydrochloride, methionine, threonine, tryptophan, phenylalanine, calcium pantothenate | -- | -- |
| Tsuav Meem | -- | 74 UAH |
| Elkar Levocarnitine | 26 RUB | 335 UAH |
| Carnitine levocarnitine | 426 rub | 635 UAH |
| Carnivitis Levocarnitine | -- | 156 UAH |
| Lecarnitol Levocarnitine | -- | 68 UAH |
| Khoom nyiag levocarnitine | -- | 178 UAH |
| Almba | -- | 220 UAH |
| Metacartin levocarnitine | -- | 217 UAH |
| Carniel | -- | -- |
| Cartan | -- | -- |
| Levocarnyl Levocarnitine | 241 rub | 570 UAH |
| Ademethionine Ademethionine | -- | -- |
| Neeg Hus Xov Xwm Ademethionine | 277 rub | 292 UAH |
| Pob Tsuas Yaj Ademethionine | 186 rub | 211 UAH |
| Adeline Ademethionine | -- | 712 UAH |
| Hep Art Ademethionine | -- | 546 UAH |
| Hepamethione Ademethionine | -- | 287 UAH |
| Stimol citrulline malate | 26 RUB | 10 UAH |
| Cerezyme imiglucerase | 67 000 rub | 56242 UAH |
| Luam rov ua agalsidase alpha | 168 tshiav | 86335 UAH |
| Fabrazim agalsidase beta | 158 000 rub | 28053 UAH |
| Aldurazim laronidase | 62 RUB | 289798 UAH |
| Myozyme alglucosidase alpha | -- | -- |
| Mayozyme alglucosidase alpha | 49 600 rub | -- |
| Qhov muag rau Halsulfase | 75 200 rub | 64 646 UAH |
| Elaprase idursulfase | 131 000 rub | 115235 UAH |
| Vpriv velaglucerase alfa | 142 000 rub | 81 770 UAH |
| Eleliso Taliglucerase Alpha | -- | -- |
Yuav ua li cas thiaj nrhiav tau qhov pheej yig tshuaj ntawm cov tshuaj kim?
Txhawm rau kom pom qhov pheej yig cov khoom sib piv rau cov tshuaj, cov dav dav lossis cov lus sau, ua ntej txhua yam, peb pom zoo kom them sai sai rau qhov muaj pes tsawg leeg, uas yog rau tib cov tshuaj nquag thiab qhia tau rau kev siv. Cov tshuaj sib xyaw zoo ib yam ntawm cov tshuaj yuav qhia tau tias cov tshuaj cuam tshuam nrog cov tshuaj, kws tshuaj sib npaug lossis chaw muag tshuaj. Txawm li cas los xij, tsis txhob hnov qab txog qhov ua tsis muaj zog ntawm cov tshuaj uas zoo sib xws, uas tuaj yeem cuam tshuam kev nyab xeeb thiab ua haujlwm. Tsis txhob hnov qab txog cov lus qhia los ntawm cov kws kho mob, kev noj tshuaj rau nws tus kheej tuaj yeem tsim kev puas tsuaj rau koj kev noj qab haus huv, yog li nco ntsoov sab laj rau koj tus kws kho mob ua ntej siv cov tshuaj.
Tiogamma kev qhia
LUS QHIA Pharmacological kev txiav txim Kev ntsuas rau siv Txoj kev ntawm daim ntawv thov Cov cai ntawm kev tswj hwm kev coj ntawm Thiogamma-Turbo (Thiogamma) Tiogamma Sab sij huam Cov Yuav Tsum Muaj Cev xeeb tub Yeeb tshuaj sib cuam tshuam Noj ntau dhau Daim ntawv tso tawm Tiogamma ntsiav tshuaj Thiogamma daws rau Txoj kev lis ntshav Cia rau cov neeg mob Muaj pes tsawg leeg Pharmacological pawg Yeem Lipoic acid (ntsiav tshuaj) Ntsuas: 42 Cov analogue yog pheej yig dua los ntawm 872 rubles. Lipoic acid yog qhov pheej yig tshaj Tiogamma hloov hauv nws qhov chaw ua tshuaj. Kuj tseem muaj nyob hauv daim ntawv ntawm cov ntsiav tshuaj nrog ntau yam tshuaj siv ntawm DV. Cov ntsiav tshuaj nrog qhov ntau npaum li 25 mg yog tau sau rau cov rog rog, daim siab ua haujlwm, mob siab thiab mob ntev. Cov analogue yog pheej yig dua los ntawm 586 rubles. Oktolipen - lwm cov tshuaj Lavxias, uas yog txiaj ntsig ntau tshaj li qhov "qub". Ntawm no yog tib lub DV (thioctic acid) yog siv hauv qhov tshuaj ntawm 300 mg rau ib qho tshuaj ntsiav. Kev qhia rau kev siv: mob ntshav qab zib thiab haus dej haus cawv polyneuropathy. Tialepta (ntsiav tshuaj) Ntsuam Xyuas: 29 Sab saum toj Cov analogue yog pheej yig dua los ntawm 548 rubles. Tiolepta yog yeeb tshuaj rau kev kho mob lub plab zom mov, raws li kev ua ntawm thioctic acid hauv kev siv ntau npaum li lwm cov tshuaj uas tau hais hauv nplooj ntawv no. Nws muaj tib cov npe ntawm cov ntsuas rau kev teem caij. Phiv fab muaj peev xwm ua tau. Thaum noj ntawm qhov ncauj, nws nrawm thiab nrawm rau txoj hnyuv, ua kom sib xyaw nrog zaub mov kom txo qis. Bioavailability yog 30-60% vim los ntawm cov txiaj ntsig ntawm thawj kev nkag los ntawm lub siab. Tmax txog 30 min, Cmax - 4 μg / ml. Nrog rau / hauv cov lus qhia ntawm Tmax - 10-11 feeb, Cmax thaj tsam li 20 μg / ml. Nws muaj cov nyhuv ntawm thawj zaug kis los ntawm lub siab. Nws yog metabolized hauv daim siab los ntawm sab saw oxidation thiab kev sib txuas. Tag nrho cov ntshav tshem tawm yog 10-15 ml / min. Thioctic acid thiab nws cov khoom ua kom tau mob yog txhaws los ntawm lub raum (80-90%), hauv ib qho me me - tsis hloov pauv. T1 / 2 - 25 min. Mloog zoo rau kev daws teeb meem rau kev ua ntshav thiab ua kom haum rau infusion Thiogamma Hauv / hauv, hauv daim ntawv ntawm infusions, muab maj mam (tshaj 30 feeb) ntawm ib koob ntawm 600 mg / hnub. Qhov kev pom zoo ntawm kev siv yog 2-4 lub lis piam. Tom qab ntawd, koj tuaj yeem txuas ntxiv rau kev noj tshuaj ntawm qhov ncauj Tiogamma ntawm koob tshuaj 600 mg / hnub. Lub vial nrog kev daws teeb meem yog muab tshem tawm hauv lub thawv thiab tam sim ntawd them nrog cov teeb pom kev zoo-tiv thaiv teeb meem, li thioctic acid yog rhiab rau lub teeb. Txoj kev lis ntshav yog muab ncaj qha ntawm lub khob haus dej. Tus nqi tswj hwm yog li ntawm 1.7 ml / min. Ib qho kev daws teeb meem rau Txoj kev lis ntshav yog npaj los ntawm cov mloog zoo: cov ntsiab lus ntawm 1 ampoule (muaj 600 mg ntawm thioctic acid) yog sib xyaw nrog 50-250 ml ntawm 0.9% sodium chloride tov. Tam sim ntawd tom qab npaj tiav, lub raj mis nrog cov txiaj ntsig infusion daws yog them nrog lub teeb ci-tiv thaiv rooj plaub. Txoj kev lis ntshav daws yuav tsum tau muab tam sim ntawd tom qab npaj. Qhov ntau cia lub sij hawm ntawm kev npaj daws rau infusion tsis yog ntau tshaj 6 teev Thiogamma Coated ntsiav tshuaj Sab hauv, ib zaug ib hnub, nyob rau ntawm lub plab khoob, tsis tas yuav zom thiab haus nrog ib qho me me ntawm cov kua. Lub sijhawm kho yog 30-60 hnub, nyob ntawm seb tus mob hnyav npaum li cas. Ua tau rov ua dua qhov tseeb ntawm txoj kev kho mob 2-3 zaug hauv ib xyoos. Qhov ntau zaus cov nyom tshwm sim yog qhia raws li WHO kev faib tawm: ntau zaus (ntau dua 1/10), feem ntau (tsawg dua 1/10, tab sis ntau dua 1/100), nyob rau hauv yog (tsawg dua 1/100, tab sis ntau dua 1/1000), tsis tshua muaj (tsawg dua li 1/1000, tab sis ntau dua 1/10000), tsis tshua muaj neeg (tsawg dua 1/10000, suav nrog cov xwm txheej cais). Ntawm ib feem ntawm hematopoietic system thiab lymphatic system: pinpoint hemorrhages nyob rau hauv cov qog ua kua, daim tawv nqaij, thrombocytopenia, thrombophlebitis - tsis tshua muaj mob (rau r-d / inf.), Thrombopathy - tsis tshua muaj heev (rau conc. Rau r-d / inf.) hemorrhagic ua pob liab liab (purpura) - tsis tshua pom tshwm sim (rau conc. rau r-ra d / inf. thiab r-ra d / inf.). Ntawm ib feem ntawm lub cev tiv thaiv kab mob: kev tiv thaiv kab mob tsis haum tshuaj (txog kev loj hlob ntawm anaphylactic kev poob siab) yog qhov tsis tshua muaj tshwm sim (rau lub rooj), qee qhov xwm txheej (rau qhov kawg. Rau r-d / inf. Thiab r-d / inf.). Los ntawm ib sab ntawm lub hauv nruab nrab lub paj hlwb: ib qho kev hloov lossis kev ua txhaum ntawm qhov tsis hnov saj yog qhov tsis tshua muaj heev (rau txhua daim ntawv), kev qaug dab peg yog tsis tshua muaj heev (rau conc. Los ntawm sab ntawm cov khoom hauv lub zeem muag: daim ntawv pov thawj (opopopia) yog qhov tsawg heev (rau conc. Rau r-d / inf. Thiab r-d / inf.) Ntawm qee qhov ntawm daim tawv nqaij thiab subcutaneous cov ntaub so ntswg: kev tsis haum ntawm daim tawv nqaij (urticaria, khaus, eczema, pob xoo) - tsis tshua muaj tshwm sim (rau lub rooj), qee kis (rau qhov kawg. Rau r-ra d / inf. Thiab r-ra d / inf. .). Los ntawm kev mob plab hnyuv: xeev siab, ntuav, mob plab, raws plab - tsis tshua muaj heev (rau lub rooj). Lwm qhov tsis zoo: ua xua nyob ntawm thaj chaw txhaj tshuaj (voos, liab lossis o) - muaj tsawg kawg (rau conc. Rau r-d / inf.), Muaj qee kis (rau r-d / inf.), Thaum kis sai sai kev tswj hwm ntawm cov tshuaj yuav nce ICP (muaj qhov mob hnyav nyob hauv taub hau), ua pa nyuaj (cov tshuaj tiv thaiv no ploj mus lawv tus kheej) - feem ntau (rau conc. rau r-d / inf.), tsis tshua muaj siab (rau r-d / inf.), hauv kev sib txuas nrog kev txhim kho ntxiv ntawm cov piam thaj, kev txo qis hauv cov concentration ntawm cov piam thaj hauv cov ntshav yog ua tau, thiab cov tsos mob ntawm cov ntshav qab zib yuav tshwm sim (holo) kiv taub hau, nce hws, mob taub hau, pom kev tsis meej pem) - tsis tshua muaj tshwm sim (rau conc. rau r-d / inf. thiab rooj), muaj qee kis (rau r-d / inf.). Yog tias muaj cov kev mob tshwm sim loj tuaj lossis lwm cov kev mob tshwm sim uas tsis muaj npe hauv cov lus qhia tshwm sim, koj yuav tsum qhia koj tus kws kho mob. Nrog rau kev tswj hwm ib txhij ntawm thioctic acid thiab cisplatin, qhov txo qis hauv kev ua haujlwm ntawm cisplatin tau sau tseg. Thioctic acid khi cov hlau, yog li nws yuav tsum tsis txhob raug ib txhij nrog cov kev npaj muaj hlau ions (piv txwv li hlau, magnesium, calcium). Txhim kho qhov tshuaj tiv thaiv kev tiv thaiv ntawm GCS. Nrog rau siv ua ke ntawm thioctic acid thiab insulin los yog tshuaj ntawm qhov ncauj hypoglycemic, lawv cov nyhuv tuaj yeem ua kom zoo dua. Ethanol thiab nws cov metabolites ua kom tsis muaj zog ntawm thioctic acid. Txuas ntxiv rau kev mloog zoo rau kev npaj daws teeb meem rau Txoj kev lis ntshav thiab kev daws qhov teeb meem ntawm Txoj kev lis ntshav Thioctic acid reacts nrog cov suab thaj molecules, ua rau sparingly soluble complex, piv txwv li, muaj kev daws levulose (fructose). Thioctic acid infusion daws tsis sib haum nrog kev daws teeb meem ntawm dextrose, Ringer thiab cov kev daws teeb meem uas cuam tshuam nrog disulfide thiab SH-pawg. Cov tsos mob ntawm kev siv tshuaj ntau dhau hwv lawm Tiogamma: xeev siab, ntuav, mob taub hau. Kev noj tshuaj li ntawm 10 txog 40 g ntawm thioctic acid nyob rau hauv kev sib xyaw nrog kev haus cawv, cov neeg quav cawv tau pom, txog rau qhov ua rau muaj kev tuag. Cov tsos mob ntawm kev haus ntau dhau: psychomotor kev ntxhov siab lossis stupefaction, feem ntau ua raws li kev txhim kho ntawm cov leeg chua leeg thiab lactic acidosis. Kuj tau piav qhia txog cov neeg mob ntshav qab zib, kev poob siab, rhabdomyolysis, hemolysis, tshaj tawm kev sib kis mob ntshav hauv hlwb, mob hlwb pob txha thiab ntau yam hauv lub cev tsis ua haujlwm. Kev Kho Mob: tsos mob. Tsis muaj ib qho tshuaj tua kab mob tshwj xeeb. Thiogamma - mloog zoo rau kev npaj ntawm kev daws rau infusion, 30 mg / mlCov. 20 ml hauv ampoules ua los ntawm cov iav xim av (hom I). Daim ntawv dawb yog thov rau txhua lub ampoule nrog xim. 5 ampoules tau muab tso rau hauv cov thawv ntawv thawv nrog cov dividers. Ntawm 1, 2 lossis 4 pallets ua ke nrog lub rooj sib hais tiv thaiv kev tiv thaiv uas ua los ntawm PE dub, tso rau hauv lub thawv ntawv thawv. Thiogamma - kev daws rau kev lis ntshav, 12 mg / mlCov. 50 ml hauv lub fwj ua los ntawm cov iav xim av (hom II), uas yog kaw nrog cov roj hmab nres. Cov paib yog tsau siv cov ntawv txhuas, ntawm lub sab saud uas muaj cov polypropylene gaskets. 1 lossis 10 lub raj mis nrog dai teeb-tiv thaiv cov teeb meem (raws li tus naj npawb ntawm lub raj mis) ua los ntawm PE dub thiab daim duab los ua daim npav yog muab tso rau hauv lub thawv ntawv thawv. Thiogamma - ntsiav tshuaj coated, 600 mgCov. 10 ntsiav tshuaj hauv cov hlwv ua los ntawm PVC / PVDC / txhuas ntawv ci. 3, 6 lossis 10 hlwv muab tso rau hauv lub thawv ntawv thawv. 1 ampoule ntawm mloog zoo rau kev npaj ntawm kev daws rau Txoj kev lis ntshav Tiogamma muaj cov tshuaj nquag: meglumine thioctate 1167.7 mg (sib raug rau 600 mg ntawm thioctic acid). Cov tub zog: macrogol 300 - 4000 mg, meglumine - 6-18 mg, dej rau kev txhaj tshuaj - txog 20 ml 1 lub raj mis ntawm Tiogamma Txoj kev lis ntshav kua muaj cov tshuaj nquag: meglumine ntsev ntawm thioctic acid 1167.7 mg (sib xyaw rau 600 mg thioctic acid). Cov muaj mob siab: macrogol 300 - 4000 mg, meglumine, dej rau txhaj tshuaj - txog li 50 ml. 1 Thiogamma Coated Tablet muaj cov tshuaj nquag: thioctic acid 600 mg. Cov zam: hypromellose - 25 mg, colloidal silicon dioxide - 25 mg, MCC - 49 mg, lactose monohydrate - 49 mg, sodium carmellose - 16 mg, talc - 36.364 mg, simethicone - 3.636 mg (dimethicone thiab silicon dioxide colloidal 94: 6 ), magnesium stearate - 16 mg, plhaub: macrogol 6000 - 0.6 mg, hypromellose - 2.8 mg, talc - 2 mg, sodium lauryl sulfate - 0.025 mg. Cov neeg mob ntshav qab zib yuav tsum tau soj ntsuam cov ntshav qabzib tas mus li, tshwj xeeb yog pib kho. Qee qhov xwm txheej, nws yog ib qho tsim nyog yuav tau txo qhov koob tshuaj insulin los yog qhov ncauj qhov ncauj qog ntshav hauv qhov ncauj kom tsis txhob muaj kev txhim kho hypoglycemia. Yog tias cov tsos mob ntawm tus mob ntshav qab zib tsawg tshwm sim (kiv taub hau, tawm hws ntau dhau, mob taub hau, pom kev txawv txav, xeev siab), txoj kev kho yuav tsum nres tam sim ntawd. Hauv cov kis tshwj xeeb, thaum siv cov tshuaj Tiogamma hauv cov neeg mob uas tsis muaj glycemic tswj thiab nyob rau hauv ib qho mob hnyav, qhov mob nyhav tsis nco qab yuav ua rau mob loj tuaj. Cov neeg mob uas siv Thiogamma yuav tsum tsis txhob haus cawv. Kev haus dej cawv thaum lub sij hawm kho nrog Tiogamma txo cov nyhuv kho thiab yog qhov kev pheej hmoo ua rau muaj kev txhim kho thiab kev vam meej ntawm kev mob neuropathy. Cuam tshuam rau lub peev xwm los tsav tsheb lossis ua haujlwm uas yuav tsum muaj kev nce ceev ntawm lub cev thiab lub hlwb. Kev Siv Tiogamma tsis muaj kev cuam tshuam cov peev xwm tsav lub cev muaj zog thiab ua haujlwm nrog lwm cov txheej txheem. Ntxiv rau qhov ntxig ntsiav tshuaj. Cov neeg mob uas tsis tshua muaj keeb kab mob fructose intolerance, glucose-galactose malabsorption syndrome lossis glucose-isomaltose tsis txaus yuav tsum tsis txhob noj Tiogamma. Ib qho tshuaj pleev ib ce ntawm Tiogamma 600 mg muaj qis dua 0.0041 XE.
ntawm kev siv cov tshuaj
Tiogamma
Cov tshuaj phiv tshuaj Thiogamma (Thiogamma-Turbo) yog thioctic (alpha-lipoic) acid. Thioctic acid tsim nyob rau hauv lub cev thiab pabcuam ua lub coenzyme rau lub zog metabolism ntawm alpha-keto acids los ntawm oxidative decarboxylation. Thioctic acid ua rau cov ntshav qabzib tsawg zuj zus, ua rau cov ncauj lus glycogen ntau zog hauv hepatocytes. Kev ua kom tsis haum plab los yog tsis muaj thioctic acid yog pom nrog ntau cov khoom sib ntxiv nyob rau hauv lub cev (piv txwv li, lub cev ketone), zoo li thaum intoxication. Qhov no ua rau muaj kev ntxhov siab hauv cov xov aerobic glycolysis. Thioctic acid muaj nyob rau hauv lub cev hauv daim ntawv ntawm 2 daim ntawv: txo thiab oxidized. Ob daim ntawv no yog physiologically dhia, muab cov tshuaj antioxidant thiab anti-toxic los.
Thioctic acid tswj kev ua kom cov metabolism ntawm carbohydrates thiab cov rog, zoo cuam tshuam cov metabolism hauv cov roj cholesterol, muaj cov kab mob hepatoprotective, txhim kho daim siab ua haujlwm. Muaj txiaj ntsig zoo rau kev rov ua dua tus txheej txheem hauv cov nqaij thiab cov plab hnyuv siab raum. Lub zog thaj tsam ntawm thioctic acid zoo ib yam li cov teebmeem ntawm cov vitamins B. Thaum lub sijhawm pib hla lub siab, thioctic acid muaj kev hloov pauv tseem ceeb. Hauv cov tshuaj muaj yees, pom tias cov tib neeg cov kev hloov pauv txawv.
Thaum siv sab hauv, nws yog sai thiab yuav luag nqus los ntawm cov hnyuv. Kev txiav txim siab tau tau nrog cov oxidation ntawm ib sab ntawm cov thioctic acid thiab nws txoj kev txuas. Kev tshem tawm ib nrab-lub neej ntawm Tiogamma (Tiogamma-Turbo) yog los ntawm 10 txog 20 feeb. Tsau tawm hauv cov zis, nrog metabolites ntawm thioctic acid predominating.
Nrog rau cov ntshav qab zib ua kom yoog txhawm rau txhim kho cov nqaij mos rhiab mob.
Thiogamma-Turbo, Thiogamma rau kev tswj hwm kev ua niam txiv
Thiogamma-Turbo (Thiogamma) yog npaj rau kev tswj hwm los ntawm tsoomfwv los ntawm cov leeg ntshav hla dej. Rau cov laus, ib koob tshuaj 600 mg (txheem ntawm 1 vial lossis 1 ampoule) yog siv ib hnub ib zaug. Txoj kev lis ntshav yog nqa tawm maj mam, rau 20-30 feeb. Lub chav kawm ntawm kev kho mob yog kwv yees li 2 txog 4 lub lis piam. Yav tom ntej, kev siv sab hauv ntawm Tiogamma hauv cov ntsiav tshuaj yog qhov pom zoo. Kev tswj hwm hauv tsoomfwv ntawm Thiogamma-Turbo lossis Thiogamma rau kev lis ntshav yog kho rau kev mob rhiab heev uas cuam tshuam nrog kev mob ntshav qab zib polyneuropathy.
Cov ntsiab lus ntawm 1 lub raj mis ntawm Thiogamma-Turbo lossis 1 ampoule ntawm Thiogamma (600 mg ntawm cov tshuaj) yog yaj nyob rau hauv 50-250 ml ntawm 0.9% sodium chloride tov. Tus nqi ntawm kev tso ntshav tawm - tsis ntau tshaj 50 mg ntawm thioctic acid hauv 1 feeb - qhov no kwv yees sib piv rau 1.7 ml ntawm ib qho kev daws ntawm Thiogamma-Turbo (Thiogamma). Kev noj tshuaj diluted yuav tsum siv tam sim ntawd tom qab sib xyaw nrog cov kuab tshuaj. Thaum lub sijhawm infusion, txoj kev daws teeb meem yuav tsum muaj kev tiv thaiv los ntawm lub teeb los ntawm cov khoom siv tshwj xeeb lub teeb tiv thaiv.
Cov ntsiav tshuaj yog npaj rau kev siv sab hauv. Nws raug nquahu kom sau ntawv mus rau 600 mg ntawm cov tshuaj 1 zaug nyob rau ib hnub. Cov ntsiav tshuaj yuav tsum nqos tag nrho, noj tsis hais txog zaub mov, ntxuav cia nrog cov dej txaus. Lub sijhawm tiv thaiv kev kho ntsiav tshuaj yog los ntawm 1 mus rau 4 hlis.
Nruab nrab hauv lub paj hlwb: hauv cov tsis tshua muaj tshwm sim, tam sim ntawd tom qab siv cov tshuaj nyob rau hauv daim ntawv ntawm Txoj kev lis ntshav, txiav cov leeg txhaws muaj peev xwm ua tau.
Cov plab hnyuv siab raum: ua txhaum ntawm qhov xav ntawm saj, diplopia.
Hematopoietic system: purpura (mob tawm pob), mob thrombophlebitis.
Cov tshuaj tiv thaiv tsis haum ntshav: lub cev tsis haum tshuaj tuaj yeem ua rau anaphylactic ceeb, eczema lossis urticaria ntawm qhov chaw txhaj tshuaj.
Digestive system (rau Tiogamma ntsiav tshuaj): dyspeptic manifestations.
Lwm yam: yog tias Thiogamma-Turbo (lossis Thiogamma rau kev tswj hwm kev coj noj coj ua) raug tswj hwm sai, kev nyuaj siab ua pa thiab qhov zoo ntawm tawm tsam hauv lub taub hau yog qhov ua tau - cov kev cuam tshuam no nres tom qab txo qis kev lis ntshav. Kuj tseem ua tau: hypoglycemia, kub tso xim, kiv taub hau, tawm hws, mob hauv lub plawv, txo ntshav qabzib, xeev siab, pom kev plooj, mob taub hau, ntuav, tachycardia.
• Cov mob rau cov neeg mob uas yooj yim ua rau muaj kev mob hnyav lactic acid (rau Thiogamma-Turbo lossis Thiogamma rau kev tswj hwm kev saib xyuas),
• menyuam hnub nyoog,
• lub sijhawm cev xeeb tub thiab lactation,
• kev fab tshuaj tiv thaiv thioctic acid lossis lwm yam ntawm Thiogamma (Thiogamma-Turbo),
• mob rau daim siab mob heev lossis mob raum,
• mob theem ntawm myocardial infarction,
• ua rau lub ntsws ua pa lossis lub plawv khiav tsis zoo,
• lub cev qhuav dej,
• haus dej cawv ntev,
• cov kev huam yuaj ntawm cerebrovascular.
Thaum cev xeeb tub lossis pub mis niam, kev siv ntawm Thiogamma thiab Thiogamma-Turbo tsis pom zoo, vim tias tsis muaj kev paub txaus los ntawm kev siv tshuaj kho mob.
Qhov ua tau zoo ntawm cov tshuaj hypoglycemic thiab insulin yog nce ntxiv nrog Thiogamma (Thiogamma-Turbo). Txoj kev daws teeb meem Thiogamma-Turbo lossis Thiogamma yog tsis sib haum nrog cov kuab tshuaj uas muaj cov suab thaj nyob rau hauv, vim thioctic acid ua rau insoluble complex sib txuas nrog cov piam thaj. Hauv kev sim tshuaj hauv vitro, thioctic acid hnov mob nrog hlau ion nyuaj. Piv txwv li, qhov sib xyaw ua ke nrog cisplantine, magnesium, thiab hlau tuaj yeem txo cov nyhuv ntawm tom qab thaum ua ke nrog thioctic acid. Cov kuab tshuaj uas muaj cov tshuaj uas cuam tshuam nrog disulfide tebchaw lossis SH pawg tsis yog siv los daws qhov teeb meem ntawm Thiogamma-Turbo (Thiogamma) (piv txwv li, lub suab li tshuaj).
Nrog rau kev noj tshuaj ntau dhau ntawm Tiogamma (Tiogamma-Turbo), mob taub hau, ntuav, thiab xeev siab yog tau. Kev kho yog mob.
Tiogamma Turbo
Tshuaj rau cov niam txiv infusion hauv 50 ml vials (1.2% thioctic acid). Hauv pob ntawv - 1, 10 fwj. Cov teeb kis tshwj xeeb hauv chaw ua si suav nrog.
600 mg coated ntsiav tshuaj rau kev siv sab hauv. Hauv pob ntawm 30, 60 ntsiav tshuaj.
Ib qho kev daws teeb meem rau kev tswj hwm hauv tsoomfwv hauv ampoules ntawm 20 ml (3% thioctic acid). Hauv pob - 5 ampoules.
Hauv qhov chaw tiv thaiv los ntawm lub teeb, ntawm qhov kub li 15 txog 30 degrees Celsius. Kev daws npaj rau kev nkag rau txoj kev lis ntshav tsis yog nyob rau hauv cia. Ampoules thiab vials yuav tsum tsuas yog nyob hauv lub ntim thawj.
Tiogamma Turbo
Cov tshuaj nquag (hauv 50 ml): thioctic acid 600 mg.
Cov tshuaj ntxiv: dej rau txhaj, macrogol 300.
50 ml ntawm Tiogamma-Turbo infusion daws muaj meglumine ntsev ntawm alpha-lipoic acid nyob rau hauv ib qho nyiaj ntawm 1167,7 mg, uas sib haum rau 600 mg ntawm thioctic acid.
Tiogamma
Cov tshuaj uas muaj sia (hauv 1 ntsiav tshuaj): thioctic acid 600 mg.
Cov tshuaj ntxiv: colloidal silicon dioxide, microcrystalline cellulose, talc, lactose, methylhydroxypropyl cellulose.
Tiogamma
Cov tshuaj nquag (hauv 20 ml): thioctic acid 600 mg.
Cov tshuaj ntxiv: dej rau txhaj, macrogol 300.
20 ml ntawm Tiogamma infusion daws muaj meglumine ntsev ntawm alpha-lipoic acid nyob rau hauv ib qho nyiaj ntawm 1167,7 mg, uas sib haum rau 600 mg ntawm thioctic acid.
Cov tshuaj hormones, lawv cov tshuaj tiv thaiv analogues thiab cov tshuaj tiv thaiv kabmob ntshav
Pancreatic hormone-based tshuaj thiab hluavtaws hypoglycemic
Khoom cua hypoglycemic cov kab mob
Yam khoom muaj sia: Thioctic kua qaub
Ntawm lub raj mis nrog yaj Thogamma-Turbo yaj, tshwj xeeb kev tiv thaiv lub teeb raug muab tso rau, uas txuas nrog rau cov tshuaj. Thiogamma daws muaj kev tiv thaiv nrog cov khoom tiv thaiv lub teeb. Hauv kev kho mob ntawm cov neeg mob, cov ntshav qabzib yuav tsum tau ntsuas qhov tsis tu ncua, raws li kev siv tshuaj ntawm cov tshuaj insulin thiab tshuaj ntshav lub cev yuav tsum kho kom tsis txhob mob ntshav qab zib. Txoj kev kho mob thioctic acid yog txo qis nrog kev siv dej cawv (ethanol). Tsis muaj lwm cov lus ceeb toom tseem ceeb.Muaj Cov Thiogamma Hloov
Cov Tshuaj Pharmacokinetics
Txoj kev ntawm daim ntawv thov
Sab sij huam
Kev cuam tshuam nrog lwm yam tshuaj
Noj ntau dhau
Daim ntawv tso tawm
Yeem
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Cov kua nplaum: analogues, muaj pes tsawg leeg, cov lus qhia rau kev siv thiab tshuaj xyuas
Pharmacodynamics thiab pharmacokinetics Glucovans yog cov tshuaj sib xyaw ua ke hypoglycemic, tsim rau lub hauv paus ntawm metformin thiab glibenclamide. Raws li paub, metformin belongs rau cov pab pawg ntawm biguanides. ... -
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