NEURORUBIN-FORTE LACTAB > Kev khomob thiab kev tiv thaiv

Kev ntsuas rau siv
Txoj kev ntawm daim ntawv thov
Sab sij huam
Kev cuam tshuam nrog lwm yam tshuaj
Cov Yuav Tsum Muaj
Cev xeeb tub
Noj ntau dhau
Cia rau cov neeg mob
Daim ntawv tso tawm
Muaj pes tsawg leeg
Yeem

Neurorubin-Forte Lactab - ib qho kev npaj ntawm kev sib xyaw ua ke uas muaj cov vitamins neurotropic ntawm pawg B. Cov tshuaj sib xyaw ua ke - cov vitamins B1, B6, B12 yog koom nrog cov txheej txheem biochemical uas ua kom muaj kev sib kis ntawm kev lom zem raws cov hlab ntsha, cov metabolism, thiab cov metabolism ntawm cov neeg kho kom haum xeeb hauv cov hlab ntsha.
Thiamine (vitamin B1), ua kom thaj chaw hauv cov kab mob ntawm cov hlab ntsha ntawm lub paj hlwb, tau koom nrog hauv kev tsim ntawm txoj hlab ntaws ua pa, txhim kho kom rov ua dua ntawm cov hlab ntaws. Thaum loj hlob ntau ntawm thiamine nyob rau hauv cov ntshav, nws txhawb txoj kev txhim kho ntawm cov nyhuv analgesic.
Pyridoxine (vitamin B6) cuam tshuam rau cov qauv thiab ua haujlwm ntawm cov leeg hlwb, ua ntej los ntawm kev tswj cov metabolism hauv cov amino acids, uas tiv thaiv kev tsub zuj zuj ntawm cov tshuaj lom neurotropic - ammonia. Koom nrog cov khoom sib txuas ntawm ntau cov kws kho kom haum xeeb: catecholamines, histamine, GABA, ntxiv cov khw muag khoom noj ntawm magnesium, uas yog lub luag haujlwm tseem ceeb hauv kev zom zaub mov, uas yog, lub zog ua haujlwm thiab cov kev ua haujlwm ntawm cov leeg hlwb.
Cyanocobalamin (vitamin B12) provokes nucleic acid metabolism thiab koom tes, yog li, hauv kev tswj hematopoiesis, thiab tseem txo cov neurogenic nociception.
Cov Tshuaj Pharmacokinetics
Thiamine mononitrate (vitamin B1) tom qab kev tswj hwm ntawm ncauj tau resorbed nyob rau hauv duodenum thiab hnyuv me. Txog rau qhov tseem ceeb, nws yog metabolized hauv daim siab thiab nws cov metabolites tseem ceeb yog thiaminocarboxylic acid thiab pyramine (2,5-dimethyl-4-aminopyridimine). Metabolites ua ke nrog ib qho me me ntawm cov thiamine tsis hloov pauv yog raug tso tawm los ntawm txoj hnyuv thiab lub raum.
Pyridoxine hydrochloride (vitamin B6) yog nqus tau sai sai los ntawm txoj hnyuv tawm. Nws yog metabolized hauv daim siab nrog kev tsim cov pharmacologically nquag metabolites ntawm pyridoxalphosphate thiab pyridoxamine phosphate. Vitamin B6 ua haujlwm xws li coenzyme tom qab phosphorylation ntawm pawg CH2OH hauv lub luag haujlwm 5, hauv lwm qhov lus tsim ntawm pyridoxal 5-phosphate (PALP). Li ntawm 80% ntawm PALP khi rau cov ntshav protein. Pyridoxine accumulates rau ntau dua ntawm cov leeg, mob siab thiab mob hauv nruab nrab. Kev npaj zaum kawg rau pyridoxine metabolism yog 4-pyridoxyl acid, uas yog cais tawm los ntawm lub raum.
Cyanocobalamin (Vitamin B12). Qhov nyiaj ntau ntawm cyanocobalamin yog nqus tau tom qab khi rau Tsev Teev Ntuj Castle hauv yam. Vitamin B12 accumulates rau ntau dua hauv daim siab. T1 / 2 los ntawm ntshav dej yog kwv yees li 5 hnub, los ntawm nplooj siab - txog 1 xyoo. Nws yog tawm feem ntau nrog cov kua tsib thiab tso zis.

Kev ntsuas rau siv

Neurorubin-Forte Lactab Nws raug nquahu kom koom ua txoj haujlwm nrog txhua txoj kev kho:
- neuralgia, neuritis, mob polyneuritis,
- neuropathy, mob polyneuropathy (suav nrog ntshav qab zib, haus dej cawv),
- Neurological ua qauv qhia ntawm osteochondrosis ntawm tus txha nqaj qaum (sciatica, radiculopathy, leeg-tonic syndromes).

Txoj kev ntawm daim ntawv thov

Neurorubin-Forte Lactab teem rau sab hauv, ua ntej lossis thaum noj mov. Cov tshuaj tau nqos tsis tau ntxo, ntxuav nrog qhov muaj dej txaus.
Cov neeg laus raug hais kom noj 1-2 ntsiav tshuaj /
Lub sij hawm ntawm kev kho mob yog 4 lub lis piam. Lub sijhawm ntawm kev coj rov ua chav kawm ntawm kev kho yog txiav txim siab los ntawm tus kheej mus ntsib kws kho mob.

Sab sij huam

Ua xua: qee zaus - ua pob khaus, khaus khaus, ua tsis taus pa, Quincke's edema, ceeb toom tsis nco ceev.
Los ntawm cov txheej txheem hauv plab: qee lub sijhawm - xeev siab, lub plab zom mov hauv plab, nce kev ua haujlwm ntawm AST.
Los ntawm cov hlab plawv system: nyob rau hauv tus neeg mob cais tawm - tachycardia, tsaus muag, cyanosis, pulmonary edema.
Tus so: qee zaus - tawm hws sai sai, lub siab tsis paub pab, kiv taub hau, ntxhov siab, mob ntxau, inhibition of prolactin secretion.

Kev cuam tshuam nrog lwm yam tshuaj

Txij li pyridoxine hydrochloride provokes decarboxylation ntawm L-dopamine (levodopa) thiab tej zaum yuav txo cov nyhuv kho mob ntawm cov tshuaj no hauv kev kho mob rau cov neeg mob Parkinson tus kab mob, kev siv ib txhij ntawm cov tshuaj no yuav tsum raug cais tawm.
Thiosemicarbazone thiab 5-fluorouracil txo cov txiaj ntsig ntawm cov vitamins B1, ua nws cov tshuaj thaiv kev.
Antacids ua rau kom qeeb ntawm qhov nqus ntawm vitamin B1.

Daim ntawv tso tawm

Neurorubin-Forte Lactab - Tshuaj.
Pob - 20 ntsiav tshuaj.

Neurorubin-Forte Lactab muaj cov tshuaj nquag: thiamine mononitrate (vit. B1) 200 mg, pyridoxine hydrochloride (vit. B6) 50 mg, cyanocobalamin (vit. B12) 1 mg.
Cov neeg mob: hypromellose, mannitol, plua plav cellulose, microcrystalline cellulose, pregelatinized hmoov txhuv nplej siab, magnesium stearate, colloidal silicon dioxide.
Cov sib xyaw ua ke ntawm cov zaj duab xis membrane: hypromellose, macrogol 6000, talc, titanium dioxide (E171), erythrosine (E127).

NEURORUBINE FORTE TABLETES N20

Lub Npe: Neurorubine

Pharmacological kev txiav txim:
Kev npaj muaj cov vitamins muaj dej-soluble B. vitamins muaj ntau cov kev ua haujlwm lom neeg, txawm hais tias zoo li pharmacological zoo ib yam, txhua yam ntawm cov vitamins muaj cov nyhuv tshwj xeeb hauv tib neeg lub cev. Hauv particular:
Vitamin B1 siv lub luag haujlwm tseem ceeb hauv cov metabolism hauv kev ua kom yuag, nrog nws lub cev tsis muaj qhov nce ntawm cov kab mob lactic thiab pyruvic acids hauv lub cev tau sau tseg. Koom nrog kev deamination thiab kev hloov pauv ntawm cov amino acids, yog li tswj kev noj zaub mov protein. Hauv cov rog metabolism, cov vitamins B1 tswj kev tsim ntawm fatty acids thiab catalyzes hloov dua siab tshiab ntawm carbohydrates rau rog. Cov foos ntawm cov vitamins no txhawb cov hnyuv kom zoo thiab ua haujlwm zais cia. Vitamin B1 ua kom cov ion txuas hauv cov kab mob ntawm cov xov ntawm neurons, yog li cuam tshuam rau kev ua tiav ntawm kev xav hauv cov hlab ntaws.

Vitamin B6 koom nrog hauv cov tshuaj ntawm cov enzymes, protein thiab rog metabolism hauv. Daim ntawv nquag ua haujlwm ntawm cov vitamin no muaj feem cuam tshuam nrog ntau yam kev cuam tshuam ntawm enzymatic uas yog coenzyme. Pyridoxine tswj hwm kev tsim kho ntawm neurotransmitters nyob rau hauv lub synapses ntawm lub hauv nruab nrab thiab peripheral systems, koom nrog tsim cov myelin membrane ntawm cov neurons. Nws txhim kho kev tsim hluav taws xob, koom rau hauv lipid thiab protein metabolism, thiab tswj cov hemoglobin synthesis.

Vitamin B12 ua lub luag haujlwm tseem ceeb hauv cov metabolism hauv protein, tswj cov kev sib txuas ntawm cov amino acids, purines thiab nucleic acids. Cyanocobalamin yog qhov tsim nyog rau cov chav kawm ib txwm ntawm cov txheej txheem ntawm myelination ntawm cov neurons thiab tsim muaj cov acetylcholine. Kev txhaj tshuaj cyanocobalamin ntau dua txhawm rau ua kom zoo dua cov kev sib txuas ntawm cov hlab ntaws raws cov qauv ntawm cov leeg hlwb thiab nthuav tawm cov kev tsim dua tshiab ntawm cov hlab ntsha. Ib qho haujlwm tseem ceeb ntawm cov vitamin B12 yog nws cov txiaj ntsig antianemic. Cyanocobalamin muaj cov nyhuv hematopoietic, txhawb lub zog erythropoiesis. Vitamin B12 txhim kho hepatic hematopoiesis, ua kom cov ntshav coagulation system, thiab pab txo cov roj cholesterol.

Cov tshuaj Neurorubin muaj kev kho mob siab ntawm cov vitamins saum toj no, uas ua ke pab txhawb rau kev ua haujlwm ntawm lub luag haujlwm ntawm cov hlab ntsha tsis zoo thiab tswj cov lipid, carbohydrate thiab protein metabolism. Tsis tas li ntawd, kev sib xyaw ntawm B vitamins pab txo qis mob nrog neuralgia ntawm ntau lub hauv paus pib.

Cov tshuaj pharmacokinetics ntawm cov tshuaj Neurorubin yog vim yog lub chaw muag tshuaj ntawm nws cov khoom sib txuas:
Thiamine mononitrate tom qab kev tswj hwm ntawm qhov ncauj, nqus ntawm thiamine feem ntau tshwm sim hauv txoj hnyuv, duodenum thiab jejunum. Qhov tshuaj me me tau nqus mus rau hauv lub siab, cov tshuaj yaj yeeb hauv lub cev nrog kev tsim muaj thiaminocarboxylic acid thiab pyramine. 30 feeb tom qab kev tswj hwm ntawm qhov ncauj, qhov tseem ceeb ntawm cov tshuaj hauv cov ntshav muaj qis dua hauv cov plab hnyuv siab raum thiab cov ntaub so ntswg. Nws yog tawm hauv lub cev los ntawm lub raum thiab los ntawm txoj hnyuv, ob qho tib si tsis hloov pauv thiab hauv daim ntawv ntawm metabolites.
Pyridoxine hydrochloride zoo rau hauv txoj hnyuv, metabolized hauv lub cev nrog kev tsim cov metabolites ntawm pyridoxal thiab pyridoxamine. Tsis tas li ntawd, pyridoxal-5-phosphate yog ib hom tshuaj uas ua haujlwm, uas ua lub luag haujlwm ntawm coenzyme hauv lub cev. Pyridoxine yog tus cwj pwm los ntawm kev siab ntawm kev khi rau cov ntshav plasma protein (txog 80%). Cumulation ntawm cov tshuaj hauv daim siab, cov leeg thiab qhov nruab nrab hauv lub paj hlwb tau sau tseg. Nws yog tawm hauv lub cev los ntawm lub raum hauv daim ntawv ntawm kev ua haujlwm thiab lub cev tsis tau.

Rau kev ib txwm nqus ntawm cyanocobalamin nyob rau hauv lawv txoj hnyuv plab, qhov muaj ntawm Castle qhov tseem ceeb yog qhov tsim nyog, uas ua kom muaj kev nqus ntawm cov tshuaj mus rau hauv cov kab mob hauv cov kab ke. Kev siv tshuaj metabolism ntawm cyanocobalamin, vim qhov kev tshwm sim uas cov nquag metabolite adenosylcobalamin tsim, tshwm sim hauv cov ntaub so ntswg. Nws tawm hauv cov zis thiab kua tsib. Nws tsawv nyob hauv lub siab. Ib nrab-lub neej ntawm cov tshuaj los ntawm cov ntshav ntshav yog 5 hnub, los ntawm daim siab mob siab - txog 1 xyoos.

Kev taw qhia rau kev siv:
Cov tshuaj yog siv rau hauv cov xwm txheej uas nrog cov tsos mob tshwm sim ntawm hypovitaminosis ntawm pab pawg B cov kab mob hauv lub cev.
Cov ntsiav tshuaj uas muaj cov yeeb yaj kiab, Neurorubin-Forte Lactab yog siv los kho qhov mob ntawm cov kab mob zoo li no:
Hnov mob hauv cov leeg thiab mob ntev ntawm cov leeg hlwb thiab mob hlwb,
Neuralgia, thiab kev puas tsuaj rau cov leeg hauv lub cev thaum qaug cawv nrog rau ntau yam tshuaj yeeb dej caw, nrog rau kev qaug cawv thiab qaug tshuaj,
Ntshav qab zib polyneuropathy.
Cov tshuaj txhaj koob tshuaj Neurorubin yog siv los ua kev kho mob lossis ntxiv nrog rau lwm cov tshuaj rau cov mob xws li:
Neuropathies, suav nrog peripheral, tshwm sim los ntawm haus dej cawv.
Ntshav qab zib polyneuropathies.
Vitamin B hypovitaminosis, qhuav thiab ntub beriberi.
Neuralgia, suav nrog cervicobrachial thiab trigeminal neuralgia.
Mob mob thiab mob hlwb thiab mob hlwb ntawm ntau cov etiologies.

Txoj kev siv:
Cov koob tshuaj ntawm cov tshuaj thiab lub sijhawm ntawm cov chav kho mob yog txiav txim los ntawm tus kws kho mob koom nrog ib tus zuj zus rau txhua tus neeg mob.
Cov ntsiav tshuaj ua yeeb yaj kiab, Neurorubin-Forte Lactab tau noj ntawm qhov ncauj nrog qhov muaj dej txaus, zoo dua ua ntej noj mov lossis thaum noj mov, nws tsis pom zoo kom faib lossis ntxo cov yeeb yaj kiab-coated ntsiav tshuaj. Cov laus feem ntau yog hais qhia 1-2 ntsiav tshuaj ib hnub. Lub sijhawm tiv thaiv feem ntau yog 1 hlis.

Cov tshuaj txhaj koob tshuaj Neurorubin yog siv rau kev txhaj tshuaj intramuscular; kev txhaj tshuaj tau pom zoo nyob rau sab saud sab saud ntawm cov nqaij gluteal.
Cov koob tshuaj ntawm cov tshuaj thiab ntau zaus ntawm kev txhaj tshuaj nyob ntawm qhov mob hnyav ntawm hypovitaminosis.
Nyob rau hauv cov mob hnyav, 3 ml ntawm cov tshuaj feem ntau tau siv tshuaj ib hnub lossis 1 zaug hauv 2 hnub kom txog thaum qhov kev sib zog ntawm qhov mob txo qis, tom qab ntawd lawv hloov mus rau 3 ml ntawm cov tshuaj 1-2 zaug hauv 7 hnub.
Hauv cov xwm txheej ntawm mob hnyav, 3 ml ntawm cov tshuaj feem ntau yog ua 1-2 zaug hauv 7 hnub.
Lub sijhawm tiv thaiv kev kho mob nrog cov mob Neurorubin yog nyob ntawm qhov ua rau ntawm hypovitaminosis. Thaum ua qhov kev kho cov tshuaj mus ntev, cov kev ntsuas hauv tsev kuaj yuav tsum raug saib xyuas txhua 6 lub hlis.

Phiv los sis:
Thaum siv cov tshuaj hauv cov neeg mob, cov kev mob tshwm sim hauv qab no tau sau tseg:
Los ntawm lub plab zom mov: xeev siab, ntuav, nce ntxiv ntawm hepatic transaminases hauv cov ntshav. Hauv cov neeg mob uas muaj tus neeg muaj mob rhiab ntau, ua rau lub plab zom mov tau sau tseg thaum noj cov tshuaj.
Los ntawm lub hauv nruab nrab thiab ntu ntu paj hlwb: tsis muaj zog, mob taub hau, kiv taub hau. Hauv qhov xwm txheej cais, kev ntxhov siab, nce kev chim siab thiab ntxhov siab tau sau tseg. Thaum siv cov tshuaj hauv cov tshuaj siab, qee cov neeg mob tau sau tseg qhov tshwm sim ntawm qhov pheej hnov mob puas siab ntsws neuropathy, uas tshwm sim tom qab tsis siv tshuaj.

Los ntawm cov hlab plawv: tachycardia, circulatory cev qhuav dej (pom tsuas yog nyob rau hauv cov neeg mob uas muaj kev tiv thaiv ib leeg zuj zus).
Ua xua: ua pob khaus tawv nqaij, tawm pob, ua pob khaus, thaum noj ntau dua ntawm cov tshuaj hauv cov neeg mob, kev txhim kho pob txuv tau sau tseg.
Lwm yam kev phiv: cyanosis, pulmonary edema, tawm hws. Hauv cov neeg mob uas cuam tshuam los ntawm kev tiv thaiv tsis haum rau qhov tshuaj, anaphylactoid kev tsis haum, suav nrog Quincke's edema, tuaj yeem txhim kho. Nrog rau kev tswj hwm ntawm cov tshuaj rau cov neeg mob uas muaj kev tiv thaiv tsis txaus rau cov vitamins B, kev tsis nco qab yuav tshwm sim.

Cov Tshuaj Tiv Thaiv:
Ua rau tib neeg muaj kev cuam tshuam rau cov tshuaj ntawm cov tshuaj.
Nws yog ntawv ceeb toom nrog ceev faj rau cov neeg mob kev txom nyem los ntawm psoriasis, txij li cyanocobalamin tuaj yeem ua rau tsis zoo rau hauv psoriasis.
Cov tshuaj Neurorubin nyob rau hauv daim ntawv ntawm kev daws rau kev txhaj tshuaj tsis yog siv thaum cev xeeb tub thiab lactation, nrog rau kev kho mob ntawm cov menyuam yaus hnub nyoog qis dua 16 xyoo.

Cev xeeb tub
Cov tshuaj hla cov hematoplacental barrier thiab txiav txim siab nyob rau hauv niam mis. Tsis muaj ntaub ntawv qhia txog kev nyab xeeb ntawm cov tshuaj thaum cev xeeb tub thiab lactation. Cov tshuaj no thaum cev xeeb tub tuaj yeem tsim los ntawm cov kws kho mob yog tias xav tias yuav muaj txiaj ntsig rau leej niam tshaj qhov muaj feem yuav ua rau muaj menyuam hauv plab. Yog tias nws yog ib qho tsim nyog los sau tshuaj rau lub sijhawm lactation, nws yog qhov tsim nyog los txiav txim siab txog kev txiav kev pub mis.

Kev cuam tshuam nrog lwm cov tshuaj:
Nrog rau kev siv tib lub sijhawm, cov tshuaj txo cov nyhuv kho mob levodopa, uas yuav tsum tau txiav txim siab thaum kho cov neeg mob Parkinson tus kab mob thiab kom tsis txhob siv cov tshuaj no ib txhij.
Nrog rau kev siv thooj txhij, cov tshuaj Neurorubin txhim kho kev ua kom lom rau ntawm isoniazid.
Neurorubin vim nws cov vitamin B6 muaj peev xwm txo qis kev ua haujlwm ntawm altretamine nrog rau kev siv tib lub sijhawm.
Thiosemicarbazone thiab fluorouracil yog cov tshuaj tiv thaiv vitamin B1.
Cov tshuaj siv nrog hnab ntawv thiab antacid zog txo qhov nqus ntawm cov tshuaj Neurorubin-Forte Lactab.

Noj ntau dhau
Nrog kev noj tshuaj ntau dhau ntawm cov tshuaj hauv cov neeg mob, ib qho kev nce siab ntawm qhov mob tshwm sim yuav tshwm sim.
Tsis muaj ib qho tshuaj tua kab mob tshwj xeeb. Thaum hais tias noj ntau dhau, pais plab lav thiab coj ntawm enterosorbents qhia. Kev kho yog mob. Nrog rau kev nthuav dav anaphylactic kev poob siab, glucocorticosteroids rau kev siv qog thiab antihistamines siv.

Daim ntawv tso tawm:
Cov ntsiav tshuaj, zaj duab xis-coated, 10 daim nyob rau hauv lub hlwv, 2 lub hlwv nyob rau hauv ib lub thawv cardboard.
3 ml tshuaj txhaj rau hauv ampoule, 5 ampoules hauv lub thawv ntawv thawv.

Cia rau cov neeg mob:
Cov tshuaj tau pom zoo kom khaws cia rau hauv qhov chaw qhuav kom deb ntawm kev tshav ntuj ncaj qha. Neurorubin-Forte Lactab ntsiav tshuaj tau pom zoo kom muab cia rau qhov kub ntawm 15 txog 25 degrees Celsius.
Kev daws rau kev txhaj tshuaj Neurorubin yog pom zoo kom muab cia rau qhov kub ntawm 2 txog 8 degrees Celsius.
Lub txee lub neej ntawm cov tshuaj nyob rau hauv qhov kev daws teeb meem rau kev txhaj tshuaj yog 3 xyoos.
Lub txee lub neej ntawm cov tshuaj hauv daim ntawv ntawm cov ntsiav tshuaj yog 4 xyoos.

Txhais:
Neurovitan, Milgamma.

Muaj pes tsawg leeg:
3 ml (1 ampoule) ntawm kev txhaj tshuaj muaj:
Thiamine hydrochloride - 100 mg,
Pyridoxine hydrochloride - 100 mg,
Cyanocobalamin - 1 mg.
Tshwjxeeb.

1 lub ntim zaj duab xis-txheej muaj:
Thiamine mononitrate - 200 mg,
Pyridoxine hydrochloride - 50 mg,
Cyanocobalamin - 1 mg.
Tshwjxeeb.

Lub Npe: Neurorubine

Txhais:
Neurovitan, Milgamma.

Muaj pes tsawg leeg:
3 ml (1 ampoule) ntawm kev txhaj tshuaj muaj:
Thiamine hydrochloride - 100 mg,
Pyridoxine hydrochloride - 100 mg,
Cyanocobalamin - 1 mg.
Tshwjxeeb.

1 lub ntim zaj duab xis-txheej muaj:
Thiamine mononitrate - 200 mg,
Pyridoxine hydrochloride - 50 mg,
Cyanocobalamin - 1 mg.
Tshwjxeeb.

Saib xyuas!
Ua ntej siv cov tshuaj Neurorubin koj yuav tsum sab laj ib tus kws kho mob. Phau ntawv no yog muab txhais ua lus pub dawb thiab yog rau kev qhia ua ntaub ntawv nkaus xwb. Xav paub ntau ntxiv, thov hu rau cov khw muag khoom ntim ntawv.
Qhov chaw ntawm cov lus piav qhia, cov lus qhia rau kev siv tshuaj (siv tshuaj): Site "Piluli - Tshuaj los ntawm A rau Z"

Txhawm rau tshawb nrhiav tus nqi zoo tshaj plaws rau cov tshuaj thiab cov genues analogues rau NEURORUBINE FORTE LACTAB N20 nyem qhov no:

• Cov duab yog siv rau kev ua piv txwv nkaus xwb. Cov duab ntawm cov tshuaj hauv lub xaib yuav txawv ntawm cov ntawv tiag.

Pharmacological kev txiav txim

Cov tshuaj muaj peb cov vitamins uas ntxiv thiab txhim kho kev txiav txim siab ntawm ib leeg.

Vitamin B1, los yog thiamine, koom nrog hauv cov redox kev hloov ntawm lub cev ua coenzyme. Nws siv tshuaj lom nyob rau hauv-oxidized metabolic cov khoom - pyruvic thiab lactic acids. Regulates carbohydrate, rog thiab protein metabolism.

Thiamine txhawb kev ua haujlwm ntawm kev ua kom lub siab tsis ncaj raws qhov kawg ntawm cov hlab, txhim kho cov metabolism hauv ntawm neurons. Kev tswj plab hnyuv kom ua thiab plab zom mov. Nws muaj cov nyhuv ua kom mob me me hauv qhov ntau.

Nrog rau qhov tsis muaj cov vitamin B1, cov leeg mob qhov kawg (polyneuritis) cuam tshuam, tsis hnov mob, Wernicke-Korsakov syndrome (nrog rau kev quav dej cawv) yog cov tsis muaj zog.

Vitamin B6, pyridoxine - ib qho tshuaj txuam rau hauv cov protein thiab rog metabolism hauv, cov txheej txheem ua kom muaj zog ntawm cov hlab hlwb. Nws yog coenzyme ntawm kev hloov pauv ntawm cov amino acids hauv daim siab. Txhawb nqa kev sib txuas ntawm qhov tseem ceeb tshaj ntawm cov neurotransmitters ntawm nruab nrab thiab ntu ntu ntawm cov leeg ntshav: adrenaline, norepinephrine, dopamine. Nws txhim kho cov mob ntawm daim siab, txo qhov kev mob tshwm sim ntawm cov tsos mob ntawm lub cev ua ntej hauv cov poj niam: mob taub hau, o, thiab paug ntawm kev xav. Koom rau hauv cov tshuaj lus hemoglobin.

Nrog rau qhov tsis muaj vitamin B6, kev tsis txaus siab rau lub cev, o, nce ntawm cov prolactin, cov plaub hau poob, kev coj khaub ncaws, thiab dermatitis tuaj yeem tshwm sim.

Vitamin B12, cyanocobalamin - tshuaj lom neeg cov tshuaj lom neeg uas muaj cov hlau cobalt. Cuam tshuam cov protein, rog metabolism. Txhawb txoj kev faib tawm ntawm tes los ntawm kev tswj hwm kev coj ua ntawm nucleic acids. Ua kom cov qe ntshav hauv ntshav nce ntxiv, koom nrog lawv faib ua cov txheej txheem methylation. Txo cov roj cholesterol, homocysteine. Muaj nuj nqi zoo ntawm lub hauv nruab nrab thiab ntu ntu cov leeg hlwb. Txhawb nqa tus cwj pwm coj ntawm kev mob siab txhim kho nrog cov leeg axonal.

Nrog rau qhov tsis muaj vitamin B12, kev cuam tshuam loj heev hauv kev ua haujlwm ntawm tus txha caj qaum, txhawm rau mob ntshav tawm tsam, nce ntxiv ntawm bilirubin, roj cholesterol, homocysteine, thiab cov rog rog tuaj yeem tshwm sim.

Nrog rau qhov tsis muaj vitamin B12, kev ua kom muaj roj ntau ntawm lub siab tuaj yeem tshwm sim.

Cov Tshuaj Pharmacokinetics

Thaum noj ntawm qhov ncauj, thiamine yog nqus rau hauv txoj hnyuv thiab nkag rau hauv lub siab. Qee qhov ntawm nws yauv nkag mus rau recirculation enterohepatic. Nws yog cov tshuaj tiv thaiv thiab nthuav tawm hauv daim ntawv ntawm thiamincarboxylic acid, dimethylaminopyrimidine. Ib qho me me yog tawm tsis hloov nrog cov zis.

Pyridoxine hydrochloride, thaum noj ntawm qhov ncauj, nquag nqus thiab nkag mus rau hauv lub siab. Metabolized rau pyridoxalphosphate thiab pyridoxamine. Nws khi rau cov cab kuj cov cab hauv cov ntshav thiab nthuav tawm hauv cov leeg hauv daim pyridoxalphosphate. Nws yog tawm hauv daim ntawv ntawm pyridoxic acid.

Cyanocobalamin yoog los ntawm lub cev ua tsaug rau Tsev fuabtais sab hauv lub hauv paus uas nyob hauv plab - gastromucoprotein. Nws yog nqus hauv txoj hnyuv, khi rau hauv cov ntshav nrog protein thauj - transcobalamin thiab alpha-1-globulin. Nws khaws ntau hauv lub siab, qhov uas nws tuaj yeem khaws cia ntev txog ib xyoos. Ib nrab-lub neej ntawm cov ntshav yog 5 hnub.

Kev kho mob txoj hnyuv

Xeev siab, ntuav, kub siab, mob plab.

Siv rau lub sijhawm qub

Nws raug pom zoo rau kev siv thaum cov kws kho mob tau sau tseg thiab coj mus rau hauv tus account txhua yam kev tiv thaiv. Cyanocobalamin nce ntshav viscosity, yog li nws muaj peev xwm nce kev pheej hmoo ntawm thrombosis.

Cyanocobalamin nce ntshav viscosity, yog li nws muaj peev xwm nce kev pheej hmoo ntawm thrombosis.

Kev cuam tshuam nrog lwm yam tshuaj

Antacids thiab sorbents txo qhov nqus ntawm cov tshuaj. 6-fluorouracil, thiosemicarbazone - thiamine antagonists.

Vitamin B6 txo cov haujlwm ntawm cov tshuaj tiv thaiv Parkinsonian tshuaj Levodopa.

Neurorubin Fort tshuaj xyuas

Igor, 40 xyoo, Samara

Kuv yuav cov vitamins rau kev kho mob osteochondrosis. Muaj mob mob caj dab.Tom qab noj cov tshuaj, lawv tsis muaj zog. Nws pib zoo siab dua. Lub cev tsis muaj zog thaum sawv ntxov.

Anna, 36 xyoo, Kazan

Lub loog ntawm ko taw thiab ntiv tes tau txhawj xeeb. Tus kws kho mob neuropathologist hais kom siv cov tshuaj no. Cov tsos mob subsided. Tom qab noj cov ntsiav tshuaj, muaj mob me ntsis hauv siab, ib qho kev tshwm sim yog qhia hauv cov lus qhia. Muaj mob taub hau.

Cov Yuav Tsum Muaj

Hypersensitivity rau cov tshuaj.

Vitamin B ₁ Nws yog contraindicated rau siv nyob rau hauv kev mob tshwm sim.

Vitamin B ₆ nws yog contraindicated nyob rau hauv cov ntaub ntawv ntawm peptic rwj ntawm lub plab thiab duodenum nyob rau hauv mob mob theem (txij li thaum nce nyob rau hauv lub acidity ntawm pais plab kua txiv yog ua tau).

Vitamin B ₁₂ Nws yog contraindicated rau kev siv rau hauv erythremia, erythrocytosis, thromboembolism.

Kev tiv thaiv kev nyab xeeb zoo rau kev siv

Raws li ib txwm muaj los ntawm kev ua haujlwm tsis zoo rau cov vitamins B ₁ , Hauv ₆ thiab B ₁₂ thaum kho, kev cuam tshuam los ntawm daim tawv nqaij thiab nqaij tawv nqaij tuaj yeem tuaj yeem tshwm sim.

Pyridoxine tuaj yeem ua rau qhov tshwm sim pob txuv lossis pob ntxau ntawm daim tawv nqaij los txhim kho cov tsos mob ntawm cov uas twb muaj lawm.

Nrog rau kev qhia ntawm cov vitamin ₁₂ cov duab hauv chaw soj ntsuam, nrog rau kev kuaj sim rau tus mob funicular myelosis lossis tus mob hlwv tsis huv, tuaj yeem ploj lawv qhov tshwj xeeb.

Haus cawv thiab tshuaj yej dub txo qhov nqus ntawm thiamine.

Haus dej haus sulphite-uas muaj cawv (xws li cawv) ua rau thiamine muaj kev puas tsuaj ntau.

Vim tias cov tshuaj muaj vitamin ₆ yuav tsum tau siv nrog ceev faj hauv cov neeg mob uas muaj keeb kwm mob plab thiab duodenal mob rwj, qhia los ntawm kev ua haujlwm tsis zoo hauv lub raum thiab mob siab.

Cov neeg mob neoplasms, tsuas yog tus neeg mob nrog megaloblastic anemia thiab vitamin B tsis txaus ₁₂ yuav tsum tsis txhob siv cov tshuaj.

Cov tshuaj yog siv rau qhov mob hnyav lossis mob nyhav ntawm cov hlab plawv thiab angina pectoris.

Siv thaum cev xeeb tub thiab lactation

Cov tshuaj tsuas yog tom qab ua tiav kev soj ntsuam zoo ntawm cov txiaj ntsig / kev pheej hmoo sib piv, vim tias tsis muaj ntaub ntawv tsis txaus ntseeg txog kev nyab xeeb ntawm cov tshuaj thaum cev xeeb tub.

Cov vitamins B ₁ , Hauv ₆ thiab B ₁₂ tawm hauv cov kua mis. High Vitamin B Concentrations ₆ yuav txwv tsis pub cov mis ntxiv. Cov kev tshawb fawb txog kev tsis pub cov vitamins mus rau kev pub mis niam tsis tau tshawb nrhiav. Qhov kev txiav txim siab tsis pub niam mis los yog siv cov tshuaj yuav tsum tau txiav txim siab qhov tseem ceeb ntawm kev siv cov tshuaj rau leej niam. Yog tias tsim nyog, kev siv cov tshuaj yuav tsum tsis pub mis rau lub sijhawm no.

Lub peev xwm los cuam tshuam cov tshuaj tiv thaiv tus nqi thaum tsav tsheb lossis lwm yam txheej txheem

Cov tshuaj tsis cuam tshuam rau lub peev xwm tsav tsheb lossis ua haujlwm nrog cov txheej txheem.

Hauv qhov xwm txheej uas kiv taub hau thaum kho, ib tug yuav tsum caiv tsis txhob tsav tsheb thiab ua haujlwm nrog cov txheej txheem.

Cov menyuam yaus yuav tsum tsis txhob raug cov tshuaj, vim tias tsis muaj kev paub txog kev siv tshuaj kho menyuam yaus.

Noj ntau dhau

Vitamin B ₁ : muaj kev kho kom dav. Cov kev txhaj tshuaj ntau heev (ntau dua 10 g) ua qauv siv curariform zoo, txwv tsis pub ua kom zoo nkauj ntawm cov hlab ntaws.

Vitamin B ₆ : Nws muaj tshuaj lom tsawg heev. Kev siv mus sij hawm ntev (ntau tshaj 6-12 lub hlis) hauv kev muab tshuaj ntau dua 50 mg ntawm vitamin B ₆ txhua hnub tuaj yeem ua rau kom hnov mob puas siab ntsws neuropathy.

Kev Siv Vitamin Ntau Tshaj ₆ hauv kev noj ntau dua 1 g nyob rau ib hnub rau ntau lub hlis tuaj yeem ua rau cov leeg neurotoxic.

Neuropathies nrog ataxia thiab mob rhiab heev, mob hlwb nrog rau qhov hloov ntawm EEG, zoo li qee qhov mob hypochromic anemia thiab seborrheic dermatitis tau piav qhia tom qab kev tswj hwm ntawm ≥ 2 g nyob rau ib hnub.

Vitamin B ₁₂ : tom qab kev tswj hwm hauv tsoomfwv (hauv kev tswj hwm tsis tshua muaj, tom qab kev tswj hwm ntawm qhov ncauj), kev fab tshuaj tsis haum, eczematous tawv nqaij tsis zoo thiab daim ntawv pob ntxau ntawm cov pob txuv tau pom ntawm cov koob tshuaj ntau dua li kev pom zoo.

Nrog rau kev siv ntev hauv kev siv tshuaj ntau, qhov kev ua txhaum ntawm cov kev ua ntawm daim siab enzymes, mob hauv lub plawv, thiab hypercoagulation yog ua tau.

Kev kho mob rau qhov ncauj mus rau hauv lub cev: tshem tawm ib yam tshuaj lom (induce ntuav, yaug lub plab), ntsuas kom txo qis kev nqus (siv hluav ncaig hluav ncaig).

Sab sij huam

Los ntawm lub nruab zog: kev siv tshuaj tiv thaiv hypersensitivity, anaphylactic shock, anaphylactic shock. Kev ua xua rau muaj qhov tsis tshua muaj sia.

Los ntawm cov kab ke endocrine: prolactin tso tawm lawm.

Los ntawm lub paj hlwb: ntxhov siab, siv sijhawm ntev (ntau tshaj 6-12 lub hlis) ntawm cov vitamin ₆ ntawm koob tshuaj ≥ 50 mg txhua hnub, tuaj yeem ua rau lub qhov txhab tsis hnov qhov muag neuropathy, poob siab mob siab, malaise, kiv taub hau, kiv taub hau.

Los ntawm cov kab mob plawv: tachycardia, tsaus muag.

Ntawm ib feem ntawm kev ua pa, hauv siab thiab mediastinum: mob ntsws, mob ntsws ntsws qhuav.

Los ntawm cov hnyuv: lub plab zom mov tsis zoo, suav nrog xeev siab, ntuav, raws plab, mob plab, muaj kua qaub ntau ntawm lub plab zom mov.

Los ntawm lub siab thiab tsib zais zis: thaum siv cov koob tshuaj loj, qhov nce qib ntawm glutamic acid-transmucosal transaminase (SGOT) hauv kev ntshav cov ntshav.

Ntawm ib feem ntawm daim tawv nqaij thiab cov nqaij mos subcutaneous: xoo pob, tawv nqaij ua xua, suav nrog pruritus, urticaria.

Lwm yam kev cuam tshuam: tawm hws ntau dhau, ib qho zoo nkaus li qaug zog, kiv taub hau, tshwm sim.