Thioctacid 600 t: cov lus qhia rau kev siv

1 ampoule ntawm kev daws muaj:

Cov tshuaj nquag: 952.3 mg ntawm trometamol ntsev ntawm thioctic acid (nyob rau hauv thioctic (a-lipoic acid) - 600.0 mg.

Cov muaj mob: trometamol, dej rau kev txhaj tshuaj.

Pob tshab daj ua kua.

Pharmacological kev txiav txim

Alpha-lipoic (thioctic) kua qaub yog cov tshuaj zoo li muaj vitamin nrog coenzyme thaj chaw. Nws yog tsim nyob rau hauv lub cev thaum lub zog oxidative decarboxylation ntawm alpha-keto acids.

Ntawm cov ntshav qab zib mellitus los ntawm hyperglycemia, cov ntsiab lus ntawm cov khoom kawg glycosylation yuav nce ntxiv. Txoj kev no ua rau txo qis cov ntshav endoneural txaus thiab kev txhim kho ntawm endoneural hypoxia. Nyob rau tib lub sijhawm, nrog rau kev nce ntxiv hauv kev tsim cov dawb radicals, cov ntsiab lus ntawm antioxidants, tshwj xeeb, glutathione, poob qis.

Alpha-lipoic (thioctic) kua qaub yog cov tshuaj zoo li muaj vitamin nrog coenzyme thaj chaw. Hauv lub cev, nws tau tsim thaum lub sijhawm oxidative decarboxylation ntawm alpha-keto acids.

Ntawm cov ntshav qab zib mellitus los ntawm hyperglycemia, cov ntsiab lus ntawm cov khoom kawg glycosylation yuav nce ntxiv. Txoj kev no ua rau txo qis cov ntshav endoneural txaus thiab kev txhim kho ntawm endoneural hypoxia. Nyob rau tib lub sijhawm, nrog rau kev nce ntxiv hauv kev tsim cov dawb radicals, cov ntsiab lus ntawm antioxidants, tshwj xeeb, glutathione, poob qis.

Hauv kev tshawb nrhiav kev ua haujlwm ntawm cov nas, nws tau qhia tias alpha-lipoic acid txo kev tsim cov khoom tom kawg glycosylation, txhim kho cov ntshav endoneural, thiab nce qib glutathione. Cov ntaub ntawv no qhia tias alpha lipoic acid tuaj yeem pab txhim kho kev ua haujlwm ntawm cov hlab hlwb. Qhov no siv rau cov kev xav hnov ​​mob hauv kev mob ntshav qab zib polyneuropathy, xws li dysesthesia, paresthesia (kub hnyiab, mob, loog, tingling). Hauv kev sim kho mob hauv cov neeg mob ntshav qab zib polyneuropathy, kev tswj hwm ntawm alpha-lipoic acid tau ua rau muaj qhov txo qis hauv cov neeg hnov ​​mob nrog cov mob ntshav qab zib (mob, mob caj dab, dysesthesia, loog).

Cev xeeb tub thiab lactation

Muaj cov ntaub ntawv hais txog cov kev mob toxicological ntawm kev ua me nyuam tsis muaj sijhawm los kos kev txiav txim siab txog cov kev tsis zoo ntawm cov me nyuam hauv plab. Vim tias cov ntaub ntawv tsis txaus saib xyuas, cov tshuaj tsis pom zoo rau cov poj niam thaum cev xeeb tub.

Nws tsis paub meej tias thioctic (a-lipoic) kua qaub yuav dhau mus ua kua mis. Yog tias nws yuav tsum tau siv cov tshuaj thaum lub sijhawm pub niam mis, pub mis rau menyuam noj yuav tsum tsis pub mus ntxiv.

Tsuas tshuaj thiab tswj hwm

Cov koob tshuaj txhua hnub thaum pib ntawm kev kho mob rau qhov muaj mob ntshav qab zib ntau nyob rau hauv cov mob ntshav qab zib hnyav yog 1 ampoule ntawm Thioctacid 600 T (uas sib raug rau 600 mg ntawm thioctic acid) rau 2-4 lub lis piam.

Thioctacid 600 T tuaj yeem siv los ua ib txoj kev lis ntshav hauv ib qho isotonic sodium chloride tov (infusion ntim 100-250 ml) rau 30 feeb. Kev tswj hwm ntawm lub cev yuav tsum tau nqa tawm qeeb (tsis tshaj 50 mg ntawm thioctic acid, i.e. 2 ml ntawm kev daws ntawm Thioctacid 600 T ib feeb). Tsis tas li ntawd, kev tso dej khov ntawm cov tshuaj tsis muaj peev xwm ua tau nrog kev txhaj tshuaj los yog tshuaj pleev ib ce. Hauv qhov no, kev tswj hwm lub sijhawm yuav tsum yog tsawg kawg 12 feeb.

Kev Qhia Txoj Cai Txoj Cai

Vim tias qhov rhiab heev ntawm cov tshuaj nquag mus rau lub teeb, ampoules yuav tsum tau muab tshem tawm los ntawm cov ntawv los ntawm daim npav nkaus xwb ua ntej siv. Hauv daim ntawv ntawm cov kuab tshuaj rau kev daws teeb meem ntawm Thioctacid 600 T, tsuas yog siv cov tshuaj sodium isotonic sodium xwb. Txoj kev daws teeb meem yuav tsum muaj kev tiv thaiv los ntawm lub teeb (piv txwv, hauv txhuas ntawv ci). Kev daws rau Txoj kev lis ntshav, tiv thaiv los ntawm lub teeb, yog haum rau 6 teev.

Tom qab, lawv hloov mus rau kev saib xyuas kev kho mob nrog kev noj tshuaj ib-lipoic acid rau kev tswj hwm qhov ncauj ntawm koob tshuaj 300-600 mg ib hnub.

Lub hauv paus rau kev kho mob ntshav qab zib polyneuropathy yog txoj kev kho mob ntshav qab zib kom zoo tshaj plaws.

Noj ntau dhau

Yog tias muaj kev noj haus ntau dhau, xeev siab, ntuav, thiab mob taub hau. Tom qab kev huam yuaj los yog txhob txwm (tua tus kheej) noj alpha-lipoic acid hauv qhov ntau npaum ntawm 10 txog 40 g nrog haus cawv, kev qaug cawv hnyav tau pom, qee zaum muaj qhov ua kom tuag taus. Soj ntsuam cov cim ntawm intoxication tuaj yeem tshwm sim thawj hom kev mob hlwb lossis ntxhov siab, yav tom ntej lawv feem ntau nrog kev txiav txim siab mob qaug dab peg thiab kev txhim kho ntawm cov kab mob lactic acidosis. Tsis tas li ntawd, vim muaj kev qaug cawv nrog kev noj tshuaj ntau ntawm alpha-lipoic acid, kev mob ntshav qab zib, kev poob siab, rhabdomyolysis, hemolysis, nthuav tawm intravascular coagulation (DIC), kev tsuj cov pob txha muaj nuj nqi thiab ntau yam hauv lub cev tsis ua haujlwm tau sau tseg.

Txawm hais tias kev qaug tshuaj txhaum cai me me, Thioctacid qhia kev mus pw hauv tsev kho mob tam sim nrog kev kho mob rau kev tshem tawm. Hauv kev kho cov mob nriaj tes nriaj chua leeg, lactic acidosis thiab tag nrho lwm yam kev phom sij txog lub cev los ntawm intoxication, kev kho mob cov tsos mob yog tsim nyog. Txog rau hnub tim, qhov kev ua haujlwm ntawm hemodialysis thiab cov txheej txheem ua kom tshem tawm cov pa ntxiv kom ua kom muaj zog sai sai ntawm cov tshuaj alpha-lipoic acid tsis tau lees paub.

Kev cuam tshuam nrog lwm yam tshuaj

Nrog rau kev tswj hwm thooj txhij ntawm Thioctacid 600 T, qhov kev txo qis hauv kev ua haujlwm ntawm cisplatin tau hais tseg. Thioctacid 600 T khi cov hlau nrog kev npaj muaj hlau (piv txwv li, hlau, magnesium, calcium uas muaj cov khoom noj siv mis).

Nrog rau kev siv ua ke, cov suab thaj txo qis ntawm cov tshuaj insulin thiab cov tshuaj tiv thaiv kab mob rau kev tswj hwm qhov ncauj tuaj yeem txhim kho, yog li ntawd, kev soj ntsuam cov ntshav qabzib tsis tu ncua, tshwj xeeb tshaj yog thaum pib kho nrog Thioctacid 600 T, pom zoo. hauv cov ntshav).

Alpha lipoic acid hnov ​​mob hauv vitro nrog ionic hlau ntau txoj (piv txwv li, cisplatin). Alpha-lipoic acid cov ntaub ntawv tsis zoo rau cov txheej txheem suab thaj nrog cov suab thaj molecules. Thioctacid 600 T tsis sib xws nrog dextrose kev daws teeb meem, Lub nplhaib qhov kev daws teeb meem, thiab nrog cov kev daws teeb meem uas hnov ​​mob nrog disulfide lossis SH pawg.

Ua cov tshuaj rau cov tshuaj Thioctacid 600 T, tsuas yog siv cov tshuaj sodium isotonic sodium chloride xwb.

Kev tiv thaiv kev nyab xeeb

Kev haus dej haus cawv tsis tu ncua yog qhov muaj kev pheej hmoo rau kev txhim kho polyneuropathy thiab tuaj yeem txo cov haujlwm Thioctacid 600 T. Yog li, cov neeg mob tau qhia kom yauv tsis txhob haus cawv thaum noj tshuaj thiab thaum lub sijhawm sab nraud kho.

Nrog kev saib xyuas cov tshuaj lipoic acid npaj rau cov tshuaj tiv thaiv kab mob, kev tsis haum lub siab tau muab sau tseg, suav nrog kev poob siab (saib qhov tshwm sim "phiv"). Thaum kho, kev saib xyuas tus neeg mob tas li yog qhov tsim nyog. Thaum muaj cov tsos mob (piv txwv, khaus, xeev siab, malaise, thiab lwm yam), kev tswj hwm ntawm cov tshuaj yuav tsum nres tam sim ntawd thiab kev siv tshuaj ntxiv yuav tsum tau tsim yog tias tsim nyog.

Tom qab thov cov tshuaj Thioctacid 600 T, hloov pauv tsis hnov ​​tsw ntawm cov zis yog qhov ua tau, uas tsis muaj qhov tseem ceeb hauv tsev kho mob.