Cardiomagnyl Forte: cov lus qhia rau kev siv
Vim tias qhov muaj ntau ntawm cov kab mob plawv, txoj kev siv Cardiomagnyl yog qee qhov tseem ceeb. Cov tshuaj pab ua rau lub plawv nqus ntshav, nws cuam tshuam rau lub viscosity index thiab tiv thaiv kev tsim cov platelets.
Cardiomagnyl yog qhia raws li thawj qhov kev tiv thaiv thaum muaj qee yam tsis zoo, uas suav nrog kev rog thiab ntshav qab zib, haus luam yeeb thiab mob ntshav siab, nrog rau muaj hnub nyoog laus, thiab lwm yam. leeg tshav raug phais.
Daim ntawv tso tawm
Kev lag luam tsim cov tshuaj nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj hauv daim ntawv ntawm lub siab, uas qhia lub hom phiaj ntawm lub tshuaj. Lawv muab tso rau hauv xim av iav fwj ntawm 30 lossis 100 daim. Qhov tseem ceeb ntawm cov tshuaj yog:
- acetylsalicylic acid (tshuaj aspirin),
- magnesium hydroxide,
- hmoov txhuv nplej siab
- talcum hmoov
- tshuaj nplaum
Pharmacological cov teebmeem thiab pharmacokinetics
Acetylsalicylic acid (ASA), uas yog ib feem ntawm Cardiomagnyl, muaj ntau yam txheej txheem los tawm tsam platelet kev sib xyaw, suav nrog kev thaiv cov pa roj carbon monoxide COX-1. Tsis tas li ntawd, cov tshuaj yeeb tshuaj no yog qhov ua kom analgesic, relieves cov txheej txheem tiv thaiv kab mob thiab antipyretic. Acid tuaj yeem muaj cov txiaj ntsig tsis zoo ntawm lub plab hnyuv hnyuv; magnesium hydroxide ntxiv rau cov tshuaj tiv thaiv Cardiomagnyl rau qib nws.
Cov tshuaj pharmacokinetics ntawm cov tshuaj tsis muaj kev nyab xeeb kiag rau tib neeg lub cev.
Kev nqus thiab nqus ntawm txoj hnyuv plab tshwm sim sai thiab yuav luag tag nrho. T1 / 2 ASA yog 15 feeb; los ntawm hydrolysis, nws hloov mus rau 100 feem pua bioavailable salicylic acid. Cov txheej txheem tshwm sim nyob rau hauv ntshav ntshav, lub plab zom mov thiab daim siab.
T1 / 2 ntawm salicylic acid nrog kev txhaj tshuaj me me ntawm Cardiomagnyl yog kwv yees li 3 teev. Yog hais tias lub zog enzyme txaus siab, tus nqi ntawm qhov ntsuas tau nce siab.
Cov lus qhia: Yuav ua li cas coj Cardiomagnyl
Txhawm rau tiv thaiv kom tsis txhob rov mob cov ntshav khov thiab CVS ntawm ntau hom, nws muaj peev xwm tshaj tawm kev noj tshuaj txhua hnub ntawm 150 mg ntawm thawj theem kev kho mob, tom qab ib pliag, txo qhov koob tshuaj rau 75.
Xaj Cardiomagnyl Forte nrog kev noj tshuaj zoo tshaj
Cardiomagnyl Forte ntsiav tshuaj yog tshuaj nyob rau hauv ib qho tshuaj ntawm 1 ntsiav tshuaj / hnub. cov muaj kab mob plawv. Qhov no yog thawj zaug suav, uas yog tom qab txo.
Yuav haus li cas?
Cov tshuaj yuav tsum tau ntxuav nrog lub khob dej dawb los yog lwm yam kua. Lawv feem ntau nqos tau tag nrho, hauv qee qhov xwm txheej uas lawv tau muab tsoo lossis ib nrab ua ntej siv. Koj tuaj yeem ua zom.
Lub sijhawm ntawm hnub rau noj Cardiomagnyl
Hauv cov lus qhia ntawm cov chaw tsim khoom, koj yuav tsis pom lo lus teb rau lo lus nug: cov tshuaj yuav tsum haus thaum sawv ntxov, yav tsaus ntuj lossis thaum tsaus ntuj. Tus kws kho mob yuav tsum muaj cov kev xaiv pom zoo. Feem ntau, cov kws kho mob cov lus qhia yog nyob rau kev coj noj tshuaj thaum yav tsaus ntuj. Ntau yam qhia tau tias ib teev tom qab kev noj mov rau yav tsaus ntuj yog lub sijhawm zoo tshaj plaws los siv cov tshuaj ntshav-ntshav.
Lub sijhawm siv
Yog hais tias qhov mob hnyav heev ntawm cov kab mob plawv tau zoo, kev siv cov tshuaj yog rau cov kev cai tas mus li. Kev txiav tawm tuaj yeem cuam tshuam tsuas yog los ntawm qhov muaj qee yam contraindications. Tus neeg mob thiab tus kws kho mob kho tus neeg mob yuav tsum saib xyuas cov ntshav siab thiab ntshav coagulation. Lawv qhov txiaj ntsig zoo yuav pab txiav txim siab ncua sijhawm ntawm kev noj tshuaj.
Cia peb sim ua kom dhau qhov kev sim thiab nrhiav seb koj lub siab yog li cas.
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Kev noj tshuaj ntxiv
Nrog rau ntau yam mob ntawm cov kab mob hauv lub plawv, cov kws kho mob feem ntau sau ntawv muab tshuaj rau txhua hnub ntawm Cardiomagnyl thaum pib ntawm 150 mg. Yog tias qhov kev kho mob xav tau nyob rau hauv kev tswj txij nkawm, qhov tshuaj tsuas yog ib nrab. Hauv kev hnoos qeev myocardial infarction thiab nrog qhov tseem ceeb angina pectoris, kev noj tshuaj txhua hnub yuav muab peb npaug rau 450 mg. Mus ntsib kws kho mob thiab noj Cardiomagnyl nrog kev pib ntawm thawj cov tsos mob.
Cov Yuav Tsum Tau Ua
Muaj qee kis, cov ntshav ua kom tsis haum rau tshuaj yog siv rau kev siv. Qhov no raug pom thaum nqaij hlav ntshav tawm thiab lwm yam xwm txheej uas muaj ntshav ntau, nrog rau cov tshwm sim los ntawm lub cev tsis txaus ntawm cov vitamin K, kab mob hemorrhagic diathesis thiab thrombocytopenia. Kev siv tsis tau yam tshuaj Cardiomagnyl hauv cov neeg mob ntsws asthma. Nyob rau hauv muaj exacerbation ntawm erosive-ulcerative teeb meem thiab ua kom pom kev los ntshav hauv txoj hnyuv, cov tshuaj yuav tsum tau muab cais tawm yam tsawg kawg rau lub sijhawm.
Tus kws kho mob yuav tsum tsis txhob sau Cardiomagnyl yog tias tus neeg mob muaj ntshav qabzib-6-phosphate dehydrogenase tsis txaus thiab nyob rau kis muaj CC Qhov txaus ntshai ntawm kev siv tshuaj thaum cev xeeb tub thiab thaum pub menyuam noj yog dabtsi?
Yog tias cov kua nplaum tuaj yeem nkag mus rau hauv lub cev ntawm tus poj niam cev xeeb tub hauv thawj peb lub hlis hauv cov koob tshuaj tseem ceeb, qhov nce ntxiv ntawm cov teeb meem nrog kev loj hlob ntawm tus me nyuam hauv plab yog sau tseg. Yog tias qhov no tshwm sim hauv III ntawm lub hlis, kev ua haujlwm yog inhibited. Ua ntej lub sijhawm teem, txoj hlab ntshav ntawm lub embryo kaw, ntau npaum ntawm 300 mg / hnub provokes los ntshav. Qhov tshwm sim yog pom ob leeg hauv leej niam thiab tus me nyuam hauv plab. Qhov phom sij tshwj xeeb yog cov tshuaj loj heev, siv ze rau kev yug menyuam. Lawv tuaj yeem ua rau mob ntshav tsis so ntawm lub ntsej muag.
Kev phiv tshuaj
Kev phiv tshuaj tsis zoo nyob rau hauv Feem ntau tshwm sim ua xua. Feem ntau, cov neeg mob yws txog urticaria lossis Quincke's edema. Qee qhov xwm txheej, anaphylactic ua tau. Sab kev tshwm sim hauv lub plab zom mov muaj xws li:
Cov ntshav txhaws hauv cov hlab ntshav
- Kev kub siab (ntau dua li lwm qhov kev tshwm sim),
- ntuav thiab xeev siab
- mob nrog exacerbation ntawm o ntawm pais plab mucosa thiab duodenum 12,
- los ntshav hauv txoj hnyuv,
- nce kev ua si ntawm daim siab enzymes,
- kaus thiab stomatitis,
- nruj
- txoj hlab pas, lwm yam.
Cov hnyuv qee zaum muaj kev txob, kev hais lus hauv lub plab zom mov yog cai. Hauv cov txheej txheem ua pa, qhov tshwm sim ntawm spasmodic manifestations nyob rau hauv kev sib raug zoo nrog lub bronchus. Hauv cov kab mob hematopoietic, cuam tshuam kev cuam tshuam nyob rau hauv daim ntawv ntawm nce ntshav tuaj yeem ua tau. Qhov kev mob tshwm sim no pom tau ntau zaus. Tsawg dua qhov tsawg yog anemia. Txawm tias muaj kev mob tshwm sim tsawg dua los yog:
- ua qauv qhia ntawm agranulocytosis,
- kev mob hlwb ntawm neutropenia
- tus neeg mob tau eosinophilia.
Los ntawm kev tswj hwm ntawm Cardiomagnyl hauv cov kev mob tsis zoo, muaj qhov tsis zoo ntawm cov leeg poob siab tuaj yeem tshwm sim, uas tuaj yeem tshwm sim nws tus kheej ntawm kev mob taub hau, tinnitus, tsaug zog thiab kiv taub hau. Qhov tsis zoo tshaj plaws tshwm sim tshwm sim yuav tsum tau txiav txim siab mob ntshav tawm ntawm sab hauv.
Cov tshuaj sib cuam tshuam li cas nrog lwm cov tshuaj
Cardiomagnyl tsub kom zoo kho muaj peev xwm ntawm anticoagulants, methotrexate, tshuaj nrog hypoglycemic thaj chaw, acetazolamide, thiab lwm yam Txawm li cas los xij, nws siv tsis zoo cuam tshuam rau cov txiaj ntsig ntawm furosemide thiab ACE inhibitors.
Cardiomagnyl muaj qhov tshwm sim tsis zoo rau kev nqus ntawm cov tshuaj ntawm antacids thiab colestyramine. Nws tsis pom zoo kom sib txuas NSAIDs nrog Cardiomagnyl. Cardiomagnyl hauv kev sib xyaw nrog Probenecid yog qhov muaj teeb meem, vim tias muaj qhov ua kom tsis muaj zog ntawm kev kho mob ntawm ob qho tshuaj.
Cov tshuaj zoo sib xws: uas zoo dua
Muaj ntau ntau cov analogues ntawm Cardiomagnyl. Lawv sib txawv ob qho tib si hauv ATC code thiab cov lus sib xyaw ntawm cov feem thiab cov qauv tso tawm. Ntawm qhov nrov tshaj plaws thiab kaw los ntawm kev teeb tsa ntawm kev txiav txim tuaj yeem txheeb tau:
Feem ntau cov qauv ntawm Cardiomagnyl sib txawv hauv cov nqi tsim nyog tshaj plaws (ntawm 8 rubles). Acekardol, Fazostabil, Tromboass tsis muaj qhov sib txawv tseem ceeb hauv kev ua tau zoo ntawm daim ntawv thov, txij li lub ntsiab ua haujlwm tseem ceeb yog ASA, tab sis tseem yog lawv. Piv txwv li, Acecardol pom zoo kom noj ua ntej noj mov, thiab Cardiomagnyl tom qab. Cov tshuaj no nws txawv ntawm cov tshuaj tseem ceeb thiab lwm yam tshuaj ntxiv rau qhov tsis muaj cov tshuaj magnesium hydroxide tiv thaiv cov mucosa.
Hauv Tromboass kuj tseem tsis muaj cov tshuaj magnesium hydroxide, qhov tsis zoo yog txo qis los ntawm qhov muaj qhov tshwj xeeb kev tiv thaiv kev tiv thaiv kev tiv thaiv nyob rau hauv txoj hnyuv ntawm kev tiv thaiv membrane. Raws li cov kws kho mob thiab cov neeg mob, Tromboass thiab Phazostabil sau cia cov kev mob tshwm sim tsawg dua.
Tshuaj aspirin Cardio, ua lag luam los ntawm Bayer AG, tsis zoo li Cardiomagnyl, kuj tseem muaj daim nyias nyias ua haujlwm hauv plab hnyuv.
Cov kev tshawb fawb tshwj xeeb tau pab tsim kom muaj: Cardiomagnyl muaj txiaj ntsig zoo dua li tag nrho cov kev nkag mus rau soluble analogues thiab muaj kev cuam tshuam kev cuam tshuam ntawm platelet aggregation.
Raws li tau faib hauv khw muag tshuaj, txoj cai khaws cia
Cov tshuaj thiab cov analogues raug faib los ntawm cov khw muag tshuaj tsis muaj tshuaj. Nws yog ib qho tseem ceeb los tswj cov hnub tas sijhawm. Nws yog sib npaug rau peb xyoos. Cov khoom lag luam yuav tsum tau muab khaws cia ntawm qhov kub txog li 25 degrees, zam qhov tsis muaj hnub ci.
tus nqi rau ib pob - 30 pcs | |||
---|---|---|---|
Lub tsev muag tshuaj | Npe | Nqi | Chaw tsim tshuaj paus |
Tsev muag tshuaj Dialog | Cardiomagnyl ntsiav tshuaj 75mg + 15.2mg Tsis yog 30 | 115.00 RUB | Austria |
Tsev muag tshuaj Dialog | Cardiomagnyl (tab.pl./pr. 75 mg + 15.2 mg No. 30) | 121.00 RUB | Nyivpooj |
Evropharm RU | cardiomagnyl 75 mg 30 tab. | 135,00 rub. | Takeda GmbH |
Tsev muag tshuaj Dialog | Cardiomagnyl (tab.pl./pl. 150 mg + 30.39 mg No. 30) | 187.00 RUB | Nyivpooj |
tus nqi rau ib pob - 100 pcs | |||
Lub tsev muag tshuaj | Npe | Nqi | Chaw tsim tshuaj paus |
Tsev muag tshuaj Dialog | Cardiomagnyl ntsiav tshuaj 75mg + 15.2mg No. 100 | 200,00 rub | Austria |
Tsev muag tshuaj Dialog | Cardiomagnyl (tab.pl./pl. 75 mg + 15,2 mg No. 100) | 202.00 RUB | Nyivpooj |
Evropharm RU | cardiomagnyl 75 mg 100 tab. | 260,00 rub. | Takeda Cov Tshuaj, LLC |
Tsev muag tshuaj Dialog | Cardiomagnyl ntsiav tshuaj 150mg + 30.39mg No. 100 | 341,00 rub | Nyivpooj |
Kev tshuaj xyuas txog Cardiomagnyl hauv qhov kev nthuav dav ntawm lub ntiaj teb network feem ntau yog qhov zoo, tab sis tseem muaj ntau qhov kev ntsuas tsis zoo uas feem ntau cuam tshuam rau tus kheej cov khoom ntawm cov neeg mob thiab cov hom tsis raug ntawm cov thawj coj. Hauv kev xyuas tsis zoo, tus nqi siab ntawm cov tshuaj thiab qhov muaj tus lej ntawm cov kev mob tshwm sim feem ntau hais.
Koj tuaj yeem muab tus naj npawb ntawm cov kev txheeb xyuas los ntawm cov rooj sib tham nrov tshaj plaws thiab los ntawm kev sib raug zoo:
- Sofya Ivakina, 35 xyooCov. Tau ntev nws coj Cardiomagnyl kws kho los ntawm kws kho mob, tab sis nws strained nyob rau hauv nqe. Tus kws muag tshuaj tau hais qhia kom hloov nws nrog cov khoom pheej yig dua ntawm Trombo lub nroog Yeiuxalees. Nrog ib plab zom mov tsim txom teeb meem thiab rau cov peev nyiaj txiag.
- Petr Tukin, 45 xyoosCov. Kuv noj cardiomagnyl rau ntau tshaj 3 xyoos thaum tsaus ntuj ib teev tom qab noj hmo. Txaus siab heev nrog qhov tshwm sim.
- Vera Garina, 60 xyooCov. Cardiomagnyl kev ua kom tsawg yog qee yam cuam tshuam nrog cov pob qij txha. Kuv tsis haus ib qho kev npaj lub plawv, kuv cov pob qij txha txuas tsis mob. Kuv pib, Kuv tsis paub tias yuav muab kuv tus kheej tso rau qhov twg.
- Leon Izyumin, 55 xyooCov. Siv pheej yig analogues. Kuv tsis nyiam lawv qhov kev ua tsis tau zoo. Tam sim no kuv tsuas yog Cardiomagnyl ntsiav tshuaj. Qhov tshwm sim tsis tuaj yeem coj tau zoo dua, suav nrog ntshav siab thiab ntshav qab zib.
- Sasha Gulina, hnub nyoog 48 xyooCov. Yog tias tus nqi ntawm Cardiomagnyl yuav tsawg dua, txhua yam yuav haum kuv. Cov tshuaj zoo heev. Ntawm kev pom zoo ntawm tus kws kho mob, Kuv hloov pauv ntawm ib ntsiav tshuaj ib hnub rau ib nrab ntsiav tshuaj. Tsis pom muaj cov kev mob tshwm sim tsis zoo.
- Anatoly Petrov, 67 xyooCov. Kuv lees txais Cardiomagnyl ntau xyoo. Kuv zoo siab heev, suav nrog vim tias txij thaum pib kuv tau siv Ginkgo biloba forte ua ke. Hauv kev npaj thib ob, vascular phab ntsa txhim kho feem xyuam nrog tuaj.
- Dina Anisimova, 55 xyooCov. Nrog rau kuv lub plab mob, kws kho mob, tsis xav txog cov teeb meem, kws kho mob Cardiomagnyl, thiaj li dhau qhov teeb meem nyuaj. Kuv hloov mus rau Acecardol hauv lub sijhawm, tam sim no txhua yam yog qhov zoo. Kuv pom zoo rau txhua tus neeg uas muaj teeb meem plab mus hloov mus rau ib qho lossis lwm qhov ntawm Cardiomagnyl, uas muaj lub plhaub soluble.
Cov chaw muag tshuaj
Acetylsalicylic acid yog ib qho tshuaj tiv thaiv analgesic, anti-inflammatory thiab antipyretic thiab antiplatelet tus neeg sawv cev. Antiaggregant zog nce cov sij hawm los ntshav.
Cov nyhuv pharmacological tseem ceeb yog qhov inhibition ntawm kev tsim ntawm prostaglandins thiab thromboxane. Qhov kev ua kom loog yog ib qho txiaj ntsig ntxiv uas tshwm sim los ntawm qhov inhibition ntawm cyclooxygenase enzyme. Cov nyhuv ua rau cuam tshuam nrog kev txo ntshav siab los ntawm inhibition of PGE2 synthesis.
Acetylsalicylic acid irreversibly inhibits synthesis ntawm prostaglandins G / H, nws cov nyhuv ntawm platelets kav ntev dua li acetylsalicylic acid nyob hauv lub cev. Cov nyhuv ntawm acetylsalicylic acid ntawm lub thromboxane biosynthesis hauv platelets thiab rau lub sijhawm los ntshav tseem txuas ntxiv ntev tom qab kev kho mob tsis ua haujlwm. Qhov kev txiav txim nres tsuas yog tom qab qhov tsos ntawm cov platelets tshiab hauv cov ntshav ntshav.
Salicylic acid (kev nquag metabolite ntawm acetylsalicylic acid) muaj cov nyhuv ua rau tiv thaiv tsis zoo, thiab tseem cuam tshuam rau cov txheej txheem ua pa, lub xeev ntawm cov kua qaub-lub hauv paus ua kom lub cev thiab lub plab hnyuv. Salicylates txhawb kev ua pa, feem ntau yog cuam tshuam ncaj qha rau cov pob txha pob txha. Salicylates tsis ncaj ncaj rau kev cuam tshuam lub plab hnyuv los ntawm inhibiting nws cov vasodilator thiab cytoprotective prostaglandins thiab ua rau muaj kev pheej hmoo ntawm mob txhab.
Kev Tsis Txaus Siab Tom qab noj tshuaj acetylsalicylic acid, nws sai sai los ntawm kev zom zaub mov. Tom qab kev tswj hwm, kev nqus ntawm cov uas tsis yog-ionized daim ntawv ntawm acetylsalicylic acid tshwm sim hauv lub plab thiab cov hnyuv. Tus nqi nqus poob qis nrog kev noj zaub mov noj thiab hauv cov neeg mob uas mob taub hau, nce - hauv cov neeg mob achlorhydria lossis hauv cov neeg mob noj polysorbates lossis antacids. Qhov siab tshaj plaws hauv kev ntshav cov ntshav yog ua tiav tom qab 1-2 teev.
Kev xa Khoom. Kev khi ntawm acetylsalicylic acid rau plasma protein yog 80-90%. Kev faib khoom faib rau cov neeg laus yog 170 ml / kg lub cev hnyav. Nrog rau kev nce ntxiv hauv plasma concentration, cov chaw zov me nyuam ntawm cov protein ua haujlwm txaus, uas ua rau kev nce hauv ntim ntawm kev faib tawm. Salicylates ntev txuas rau cov plasma protein thiab kis tau sai thoob plaws lub cev. Cov tshuaj salicylates dhau mus rau hauv niam cov kua mis thiab tuaj yeem hla tus hniav placental.
Kev zom zaub mov. Acetylsalicylic acid yog hydrolyzed rau lub cev ua kom nquag plias-salicylic acid nyob rau sab hauv phab ntsa ntawm lub plab. Tom qab kev nqus, acetylsalicylic acid tau hloov sai rau salicylic acid, tab sis yog cov ntshav nyob hauv cov ntshav hauv thawj 20 feeb tom qab noj.
Xaus Salicylic acid yog metabolized hauv lub siab. Yog li, qhov sib luag siab xav tau ntawm salicylate hauv cov ntshav ntshav nce ntau dua nyob hauv qhov kev noj tshuaj sab hauv. Ntawm kev txhaj tshuaj ntawm 325 mg ntawm acetylsalicylic acid, qhov tshem tawm tshwm sim nrog kev koom nrog ntawm thawj qhov kev txiav txim kinetics. Qhov kev tshem tawm ib nrab-lub neej ua rau 2-3 teev. Nrog rau qhov siab ntawm acetylsalicylic acid, qhov ib nrab ntawm lub neej nce txog 15-30 teev. Salicylic acid tseem ua rau tsis hloov pauv hauv zis. Kev tsim tawm ntawm salicylic acid ua raws li qib koob tshuaj thiab tso zis pH. Li 30% ntawm salicylic acid yog tawm hauv cov zis yog tias cov zis cov tshuaj tiv thaiv yog alkaline, tsuas yog 2% yog tias nws muaj kua qaub. Kev tshem tawm los ntawm ob lub raum tshwm sim vim yog cov txheej txheem ntawm glomerular filtration, nquag tso pa tawm ntawm lub raum plab hlaus thiab qhov ua paug tubular reabsorption.
Mob plawv thiab mob ntsig txog mob ntshav txhaws.
Kev sib cuam tshuam nrog lwm yam tshuaj thiab lwm yam kev sib cuam tshuam
Cov txheej txheem ua kom siv tau ib txhij.
Methotrexate. Kev siv cov tshuaj acetylsalicylic acid thiab methotrexate hauv koob tshuaj 15 mg / lub lis piam lossis ntau dua nce hematological toxicity ntawm methotrexate (txo qis hauv kev ua kom zoo ntawm methotrexate nrog cov tshuaj tiv thaiv kab mob thiab hloov chaw ntawm methotrexate nrog salicylates vim cov ntshav muaj protein ntau).
ACE inhibitors. ACE inhibitors nyob rau hauv kev sib txuas nrog kev txhaj tshuaj ntau ntawm acetylsalicylic acid ua rau txo qis glomerular vim qhov inhibition ntawm vasodilatory nyhuv ntawm prostaglandins thiab txo qis hauv cov nyhuv antihypertensive.
Tshuaj Acetazolamide. Tej zaum ib qho kev nce ntxiv hauv kev ua kom tau ntawm acetazolamide tuaj yeem ua rau nkag mus ntawm salicylates los ntawm cov ntshav ntshav mus rau hauv cov ntaub so ntswg thiab ua rau lub cev muaj kuab lom ntawm acetazolamide (qaug zog, qaug zog, tsaug zog, tsis meej pem, hyperchloremic metabolic acidosis) thiab lom ntawm salicylates (ntuav, tachycardia, hyperpnoea, tsis meej pem).
Probenecid, sulfinpyrazone. Thaum probenecid thiab siab kawg ntawm cov tshuaj salicylates (> 500 mg) siv, txhua lwm cov metabolism yog suppressed thiab uric acid excretion yuav txo qis.
Kev sib xyaw ua ke kom siv nrog ceev faj.
Methotrexate. Thaum cov tshuaj acetylsalicylic acid thiab methotrexate siv rau hauv cov koob tshuaj tsawg dua 15 mg / vas thiv, hematological toxicity ntawm methotrexate ntau ntxiv (txo qis hauv kev ua kom huv ntawm methotrexate nrog cov tshuaj tiv thaiv kab mob thiab hloov chaw ntawm methotrexate nrog salicylates vim cov ntshav muaj protein ntau).
Clopidogrel, ticlopidine. Kev siv ua ke ntawm clopidogrel thiab acetylsalicylic acid muaj qhov ua haujlwm synergistic. Xws li kev siv ua ke yog nqa tawm nrog ceev faj, vim tias qhov no ua rau kom ntshav khov ntau dua.
Anticoagulants (warfarin, fenprokumon). Kev txo qis ntawm thrombin ntau lawm yog ua tau, uas ua rau muaj kev cuam tshuam ntawm qhov kev txo qis hauv cov ntshav platelet kev ua si (ib tug vitamin K antagonist) thiab kev pheej hmoo los ntshav.
Abciximab, tirofiban, eptifibatide. Nws yog qhov ua tau rau inhibit glycoprotein IIb / IIIa receptors ntawm platelets, uas ua rau muaj kev pheej hmoo los ntshav ntau ntxiv.
Heparin. Kev txo qis ntawm thrombin ntau lawm yog ua tau, uas ua rau muaj kev cuam tshuam ntawm qhov kev txo qis hauv cov ntshav ntawm kev ua si, uas ua rau muaj kev pheej hmoo los ntshav.
Yog tias ob lossis ntau qhov ntawm cov tshuaj yeeb saum toj no tau siv ua ke nrog acetylsalicylic acid, qhov no tuaj yeem ua rau muaj kev cuam tshuam ntawm kev muaj peev xwm nce ntxiv ntawm cov platelet kev ua si thiab, vim li ntawd, ntau dua hemorrhagic diathesis.
NSAIDs thiab COX-2 inhibitors (celecoxib). Kev siv sib koom ua ke nce kev pheej hmoo mob plab hnyuv, tuaj yeem ua rau lub plab zom mov tau ntshav.
Ibuprofen. Kev siv tib lub sijhawm ibuprofen tiv thaiv qhov tsis yooj yim ntawm cov platelet sib xyaw vim kev ua ntawm acetylsalicylic acid. Kev kho nrog ibuprofen nyob rau hauv cov neeg mob uas muaj kev pheej hmoo ntau ntxiv ntawm cov kab mob plawv tuaj yeem txwv cov nyhuv cardioprotective ntawm acetylsalicylic acid.
Cov neeg mob noj tshuaj acetylsalicylic acid ib hnub ib zaug los tiv thaiv kab mob plawv thiab noj ibuprofen ib lub sijhawm yuav tsum noj tshuaj acetylsalicylic acid tsawg kawg 2:00 ua ntej noj ibuprofen.
Furosemide. Kev txwv tsis pub kwv yees tubular kev tshem tawm ntawm furosemide yog ua tau, uas ua rau txo qis hauv cov nyhuv diuretic ntawm furosemide.
Quinidine. Ib qho txiaj ntsig ntxiv ntawm cov platelets yog ua tau, uas ua rau muaj kev nce ntxiv ntawm lub sijhawm los ntshav.
Spironolactone. Kev hloov pauv ntawm renin yog ua tau, uas ua rau txo qis ntawm kev ua haujlwm ntawm spironolactone.
Xaiv serotonin reuptake inhibitors. Kev siv sib koom ua ke nce kev pheej hmoo mob plab hnyuv, tuaj yeem ua rau lub plab zom mov tau ntshav.
Siv txiaj ntsig Nrog rau kev siv tib lub sijhawm nrog valproate, acetylsalicylic acid hloov chaw nws los ntawm nws cov kev sib txuas nrog cov ntshav plasma, ua kom lub cev muaj kuab lom rau tom kawg (inhibition ntawm lub hauv nruab nrab cov hlab ntsha, lub plab zom mov).
Cov tshuaj glucocorticosteroids (tsis suav nrog hydrocortisone, uas yog siv rau kev hloov kho rau Addison's disease) txo cov ntsev uas muaj ntshav ntau thiab muaj kev pheej hmoo ntawm kev noj tshuaj tshaj tom qab kho.
Tshuaj tiv thaiv kab mob kev nkeeg. Kev siv tib lub sij hawm ntawm acetylsalicylic acid thiab tshuaj tiv thaiv kab mob ntshav siab muaj feem ua rau tus mob ntshav qab zib tsawg.
Tshuaj Antacids. Kev nce ntxiv hauv lub raum thiab qhov txo qis hauv lub raum (vim tias qhov pH ntawm cov zis ntxiv) yog qhov ua tau, uas ua rau txo qis ntawm cov nyhuv ntawm acetylsalicylic acid.
Tshuaj tiv thaiv qhua pob. Co-administration nce txoj kev pheej hmoo ntawm Tus Mob Reye.
Ginkgo biloba. Kev siv sib xyaw nrog ginkgo biloba txwv tsis pub platelet sib sau, uas ua rau muaj kev pheej hmoo los ntshav ntau ntxiv.
Digoxin. Nrog rau kev siv ua ke nrog digoxin, qhov kev ua kom haum rau yav tom ntej hauv cov ntshav ntshav nce vim tias qhov ua paug txo qis raum.
Cawv pab txhawb kev puas tsuaj rau cov qog ua pa ntawm lub plab thiab ua kom ntev lub sijhawm los ntshav vim yog synergism ntawm acetylsalicylic acid thiab cawv.
Daim ntawv thov nta
Cardiomagnyl Forte siv nrog ceev faj hauv cov xwm txheej hauv qab no:
- muaj qhov tsis haum rau qhov ua kom loog, tshuaj tiv thaiv, tiv thaiv mob rheumatic, nrog rau muaj kev tsis haum rau lwm yam tshuaj,
- mob rau sab hauv lub plab, nrog rau keeb kwm ua mob rau sab hauv thiab mob rau hauv plab los yog keeb kwm ua haujlwm ntawm txoj hnyuv los ntshav
- tib lub sij hawm siv cov tshuaj tiv thaiv,
- nyob rau hauv cov neeg mob uas lub raum tsis ua haujlwm lossis cov neeg mob lub plawv tsis zoo (piv txwv li, lub raum vascular pathology, mob plawv tsis ua hauj lwm, hypovolemia, kev phais mob ntau, sepsis, los yog los ntshav ntau), vim tias acetylsalicylic acid kuj tseem tuaj yeem ua rau muaj kev pheej hmoo ntawm lub raum kev ua haujlwm thiab mob raum tsis ua haujlwm. ,
- hauv cov neeg mob uas muaj cov piam thaj loj-6-phosphate dehydrogenase tsis txaus, acetylsalicylic acid tuaj yeem ua rau hemolysis lossis hemolytic anemia. Tshwj xeeb tshaj yog thaum muaj qee yam uas tuaj yeem ua rau muaj kev phom sij ntawm hemolysis, piv txwv li, kev noj tshuaj ntau dua, kub cev lossis mob hnyav,
- ua rau lub siab ua haujlwm tsis zoo.
Ibuprofen tuaj yeem txo cov kev txwv tsis pub ua ntawm acetylsalicylic acid ntawm platelet aggregation. Kev siv tshuaj Cardiomagnyl Forte, tus neeg mob yuav tsum sab laj nrog kws kho mob ua ntej siv ibuprofen ua qhov tshuaj loog.
Acetylsalicylic acid tuaj yeem ua rau kev loj hlob ntawm bronchospasm lossis kev tawm tsam ntawm bronchial hawb pob lossis lwm yam tshuaj tiv thaiv tsis haum. Cov kev pheej hmoo ua muaj xws li keeb kwm ntawm mob ntsws asthma, quav nyab kub taub hau, lub qhov ntswg polyposis lossis mob ntsws ua pa ntev, mob ua xua (piv txwv, cov tawv nqaij ua xua, khaus, urticaria) rau lwm yam tshuaj hauv keeb kwm.
Los ntawm cov tshuaj tiv thaiv nyhuv ntawm acetylsalicylic acid ntawm platelet kev sib cais, uas txuas ntxiv rau ob peb hnub tom qab kev tswj hwm, kev siv cov tshuaj uas muaj acetylsalicylic acid tuaj yeem nce ntxiv / ntxiv kev los ntshav thaum phais (nrog rau kev phais me, xws li rho hniav).
Nrog rau kev noj tshuaj me me ntawm acetylsalicylic acid, cov tshuaj uric acid tawm tuaj yeem txo qis. Qhov no tuaj yeem ua rau muaj tus mob gout hauv cov neeg mob yooj yim.
Tsis txhob siv cov tshuaj uas muaj cov acetylsalicylic acid rau cov menyuam yaus thiab cov hluas nrog kev tiv thaiv tus mob ua pa nyuaj (ARVI), uas tau nrog lossis tsis nrog los ntawm kev nce hauv lub cev kub, tsis tas tham nrog kws kho mob. Txog qee cov kab mob kis, tshwj xeeb yog mob khaub thuas A, mob ua npaws B thiab mob qhua dej, nws muaj kev pheej hmoo ntawm kev tsim tus mob Reye's syndrome, uas yog ib yam mob uas tsis tshua muaj mob tab sis tuag taus uas yuav tsum tau mob sai sai. Txoj kev pheej hmoo yuav raug nce ntxiv yog tias acetylsalicylic acid siv los ua cov tshuaj concomitant, tab sis kev sib raug zoo hauv cov neeg tseem tsis tau muaj pov thawj hauv qhov no. Yog hais tias cov mob no nrog tus mob ntuav tas mus li, qhov no yuav yog qhov tsos mob ntawm Reye's syndrome.
Siv thaum cev xeeb tub lossis lactation
Kev txhawb nqa ntawm kev sib txuas ntawm prostaglandin tuaj yeem cuam tshuam tsis zoo thaum cev xeeb tub thiab / lossis tus menyuam hauv plab / hauv plab. Muaj kev qhia txog kev mob sib kis tau qhia tias yuav muaj teeb meem ntawm nchuav menyuam thiab menyuam tsis zoo tom qab siv prostaglandin synthesis inhibitors thaum cev xeeb tub thaum ntxov. Txoj kev pheej hmoo yuav nce raws li qhov nce ntxiv hauv koob thiab lub sijhawm kho. Raws li cov ntaub ntawv muaj, kev sib raug zoo ntawm kev noj tshuaj Acetylsalicylic acid thiab kev pheej hmoo ntawm kev nchuav menyuam tsis tau lees paub.
Cov ntaub ntawv hais txog kev sib kis ntawm kev tshwm sim tsis yog tsis zoo sib xws, txawm li cas los xij, kev pheej hmoo ntawm gastroschisis tsis tuaj yeem suav nrog kev siv cov acetylsalicylic acid. Cov txiaj ntsig ntawm kev txheeb ze ntawm qhov tshwm sim hauv lub cev xeeb tub thaum ntxov (1-4 lub hlis) nrog kev koom tes ntawm kwv yees li 14800 tus poj niam-menyuam niam txiv tsis qhia txog qhov cuam tshuam nrog kev pheej hmoo ntawm malformations.
Cov kev tshawb fawb tsiaj qhia txog kev muaj me nyuam muaj mob.
Thaum lub sijhawm kuv thiab zaum thib peb lub sijhawm cev xeeb tub, kev npaj muaj cov tshuaj acetylsalicylic acid yuav tsum tsis txhob raug tshuaj yam tsis muaj kev xav tau hauv kev saib mob. Hauv cov poj niam uas xav tias cev xeeb tub los yog thaum lub sijhawm thawj thiab thib peb lub sijhawm cev xeeb tub, cov tshuaj uas muaj acetylsalicylic acid yuav tsum muaj tsawg li sai tau, thiab lub sijhawm kho yuav tsum luv li sai tau.
Hauv III lub sijhawm cev xeeb tub, txhua tus prostaglandin synthesis inhibitors tuaj yeem cuam tshuam tus menyuam hauv qab no:
- cardiopulmonary mob toxicity (nrog lub qog ua ntshav txhaws txhaws thiab mob ntsws)
- Lub raum khiav tsis zoo uas ua tau muaj kev txhim kho lub raum ua tsis tiav nrog oligohydroamniosis,
Prostaglandin synthesis inhibitors tuaj yeem cuam tshuam rau tus poj niam thiab tus menyuam thaum kawg ntawm cev xeeb tub raws li hauv qab no:
- tau ncua sij hawm ncua sijhawm los ntshav, tiv thaiv mob antiplatelet uas tuaj yeem tshwm sim txawm tias tom qab siv tshuaj tsawg heev
- kev txwv tsis pub muaj kev sib daj sib deev, uas tuaj yeem ua rau lub sijhawm qeeb lossis nce ntxiv ntawm lub sijhawm ua haujlwm.
Dua li ntawm qhov no, acetylsalicylic acid yog contraindicated nyob rau hauv peb lub hlis thib ntawm cev xeeb tub.
Salicylates thiab lawv cov metabolites kis tau rau hauv niam cov kua mis ntawm qhov me me.
Txij li thaum tsis muaj kev cuam tshuam los ntawm cov tshuaj rau ntawm tus menyuam tau pom tom qab noj los ntawm cov poj niam thaum lactation, nws tsis tas yuav cuam tshuam los ntawm kev pub niam mis. Txawm li cas los xij, nyob rau qee kis siv tsis tu ncua lossis thaum siv cov koob tshuaj muaj menyuam ntau, nws yuav tsum tsis ua haujlwm ntxov.
Lub peev xwm los cuam tshuam cov tshuaj tiv thaiv tus nqi thaum tsav lwm yam tshuab.Tsis cuam tshuam dab tsi.
Tsuas tshuaj thiab tswj hwm
Qhov pom zoo koob tshuaj rau cov laus yog 150 mg (1 ntsiav tshuaj) ib hnub.
Cov ntsiav tshuaj tau nqos tag nrho, ntxuav nrog dej yog tias tsim nyog. Txhawm rau kom nqus tau sai, lub ntsiav tshuaj tuaj yeem zom lossis yaj hauv dej.
Lub siab ua haujlwm tsis zoo. Cov tshuaj yuav tsum tsis txhob siv rau hauv cov neeg mob uas muaj lub siab ua haujlwm tsis zoo. Koob tshuaj yuav tau muab kho rau hauv cov neeg mob lub siab tsis ua hauj lwm.
Lub raum khiav tsis zoo. Cov tshuaj yuav tsum tsis txhob siv los kho cov neeg mob uas mob raum tsis ua haujlwm (tus mob glomerular pom npaum li cas)
Raws li cov cim (saib. Ntu " Tsuas tshuaj thiab tswj hwm ») Tsis txhob siv Cardiomagnyl Forte rau menyuam yaus.
Kev siv cov tshuaj acetylsalicylic acid rau cov menyuam yaus hnub nyoog qis dua 15 xyoo tuaj yeem ua rau muaj kev phiv loj heev (suav nrog Reye's syndrome, ib qho ntawm cov tsos mob uas ntuav tsis tu ncua).
Noj ntau dhau
Toom Kev lom zem
Koob tshuaj loj. Cov neeg laus 300 mg / kg lub cev hnyav.
Tus mob salicylate ntev ntev tuaj yeem raug zais, vim nws cov cim thiab qhov tshwm sim tsis muaj qhov tseem ceeb. Kev haus dej cawv me me los ntawm salicylates, lossis salicylism tshwm sim, raws li txoj cai, tsuas yog tom qab rov qab noj ntau dua ntawm cov koob tshuaj loj.
Cov tsos mob ntawm kev mob nyhav me ntsis (tshwm sim los ntawm kev siv lub sijhawm ntev ntawm cov tshuaj ntau dua) yog kiv taub hau, lag ntseg, nce tawm hws, kub ib ce, ua pa sai, tinnitus, ua pa alkalosis, metabolic acidosis, qaug zog, nqos dej ib ce, mob taub hau, tsis meej pem, xeev siab thiab ntuav.
Mob hnyav ua rau muaj pov thawj los ntawm cov lus tshaj tawm hais txog qhov hloov pauv ntawm cov kua qaub-lub hauv paus, uas yuav txawv raws lub hnub nyoog thiab qhov hnyav ntawm intoxication. Nws nquag muaj tshwm sim hauv cov menyuam yaus yog cov tshuaj tiv thaiv metabolic acidosis. Qhov mob hnyav ntawm qhov mob tsis tuaj yeem kwv yees tsuas yog los ntawm kev saib xyuas ntawm salicylates hauv cov ntshav ntshav. Qhov kev nqus ntawm cov tshuaj acetylsalicylic acid yuav ua rau qeeb vim qeeb hauv lub plab zom zaub mov, qhov tsim kom muaj cov lej ntawm lub plab, lossis thaum npaj ua rau hauv cov qauv ntawm cov ntsiav tshuaj enteric-coated.
Cov tsos mob ntawm kev mob hnyav thiab mob hnyav (vim muaj ib qho dhau lawm): kev mob ntshav qab zib (feem ntau hauv cov menyuam yaus), mob caj dab, mob qa, mob ntshav siab, mob ntsws txhawm, mob nriaj, coagulopathy, cerebral edema, mob plawv txawv tuaj.
Ib qhov kev tshaj tawm hais txog tshuaj lom tau pom nyob hauv cov neeg mob uas muaj kev noj tshuaj ntau dhau los yog siv tshuaj yeeb, nrog rau cov neeg laus lossis menyuam yaus.
Kev Kho Mob.Nyob rau hauv cov ntaub ntawv ntawm kev haus ntau dhau, pais plab lavage thiab siv hluav taws xob qhib hluav taws yog qhov tsim nyog. Yog tias koj xav tias muaj qhov tshuaj ntau dua 120 mg / kg lub cev qhov hnyav, thov siv cov pa roj carbon ntau dua.
Ntsig txog qib salicylate yuav tsum tau ntsuas tsawg kawg txhua 2:00 tom qab noj ib koob, kom txog thaum cov dej qab ntsev tsawg zuj zus thiab cov kua qaub rov ua kom rov zoo li qub.
Lub sijhawm Prothrombin thiab / lossis MNI (International Normalized Index) yuav tsum kuaj xyuas, tshwj xeeb yog xav tias los ntshav.
Nws yog ib qho tsim nyog los kho qhov sib npaug ntawm cov kua thiab electrolytes. Cov hau kev zoo rau kev tshem tawm salicylate los ntawm ntshav ntshav yog alkaline diuresis thiab hemodialysis. Hemodialysis yuav tsum tau siv nyob rau hauv cov ntaub ntawv ntawm intoxication loj, vim tias txoj kev no ua rau nrawm nrawm nrawm ntawm salicylates thiab rov qab acid-puag thiab dej-ntsev tshuav.
Los ntawm cov teeb meem nyuaj ntsig txog kev ua rau muaj kev lom ntawm salicylate lom, qhov tshwm sim thiab cov tsos mob / cov txiaj ntsig kev sib tw yuav muaj xws li:
Neej Neeg thiab tsos mob
cov txiaj ntsig xeem
kho kev ntsuas
Txhaum me lossis mob nyhav
Lub plab zom mov, kev coj ua dua ntawm cov roj carbon activated, yuam alkaline diuresis
Tachypnea, hyperventilation, ua pa alkalosis
Rov qab ntawm electrolyte thiab acid-puag tshuav
Hyperhidrosis (tawm hws ntau)
Kev haus cawv ib nrab lossis mob hnyav
Lub plab zom mov, kev coj ua dua ntawm cov roj carbon activated, yuam alkaline diuresis, hemodialysis nyob rau hauv rooj plaub loj
Kev ua pa alkalosis nrog kev tiv thaiv metabolic acidosis
Rov qab ntawm electrolyte thiab acid-puag tshuav
Rov qab ntawm electrolyte thiab acid-puag tshuav
Kev ua pa tawm: hyperventilation, tsis-cardiogenic pulmonary edema, ua pa tsis ua haujlwm, ua tsis taus pa
Kev mob plawv: dysarrhythmias, arterial hypotension, hlab plawv tsis ua haujlwm
Piv txwv, hloov pauv ntshav siab, ECG
Kev poob ntawm cov kua thiab cov roj ntsha electrolytes, lub cev oliguria, lub raum tsis ua haujlwm
Piv txwv, hypokalemia, hypernatremia, hyponatremia, hloov pauv hauv lub raum ua haujlwm
Rov qab ntawm electrolyte thiab acid-puag tshuav
Tsis hnov qab zoo nyob hauv qabzib metabolism, ketoacidosis
Hyperglycemia, hypoglycemia (tshwj xeeb tshaj yog nyob rau menyuam yaus). Nce qib ketone
Tinnitus, lag ntseg
Lub plab zom mov: GI los ntshav
Hematologic: platelet inhibition, coagulopathy
Piv txwv li, PT ntev ntev, hypoprothrombinemia
Neurological: tshuaj lom encephalopathy thiab mob hauv lub paj hlwb txoj kev nyuaj siab nrog cov tsos mob xws li nkees, tsis meej pem, hnov qab, thiab qaug dab peg
Lub Npe Tsis Muaj Npe International
INN ntawm cov tshuaj no yog Acetylsalicylic acid + Magnesium hydroxide.
Cardiomagnyl Forte yog cov tshuaj sib xyaw ua ke los ntawm cov pab pawg ntawm cov tshuaj tsis-tshuaj steroidal uas muaj cov nyhuv tawm tsam antiplatelet.
Txoj cai rau kev siv khaus thiab kho tshuaj sib cais ntawm cov tshuaj: B01AC30.
Tso cov ntaub ntawv thiab cov nyob ua ke
Cov tshuaj muaj nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj dawb. Lawv yog oval thiab pheej hmoo ntawm ib txhais tes.
Cov muaj pes tsawg leeg ntawm cov ntsiav tshuaj muaj xws li cov tshuaj nquag:
- 150 mg acetylsalicylic acid
- 30.39 mg ntawm magnesium hydroxide.
Tus so yog excipients:
- pob kws nplej siab
- microcrystalline cellulose,
- magnesium stearate,
- cov hmoov txhuv nplej siab
- hypromellose,
- propylene glycol (macrogol),
- talcum hmoov.
Cov tshuaj muaj nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj dawb. Lawv yog oval thiab pheej hmoo ntawm ib txhais tes.
Pharmacological kev txiav txim
Acetylsalicylic acid muaj cov yam ntxwv ntawm txhua tus NSAIDs, xws li:
- Antiaggregant.
- Sau.
- Lub Tshuaj Pleev Xim.
- Antipyretic.
Lub txiaj ntsig tseem ceeb ntawm cov tshuaj no yog qhov txo qis hauv cov platelet sib sau ua ke (gluing), uas ua rau cov ntshav thooj.
Tus txheej txheem ntawm kev ua ntawm acetylsalicylic acid yog txhawm rau txhawm rau tsim cov tshuaj cyclooxygenase enzyme. Yog li ntawd, cov synthesis ntawm thromboxane hauv platelets yog cuam tshuam. Cov kua qaub no tseem ua rau cov txheej txheem ua pa thiab pob txha ua haujlwm.
Acetylsalicylic acid muaj qhov tsis zoo rau lub plab zom mov. Magnesium hydroxide pab tiv thaiv kom txhob mob plab zom mov. Magnesium tau ntxiv rau qhov kev npaj no vim nws cov khoom antacid (nruab nrab ntawm hydrochloric acid thiab ua rau lub plab ntawm lub plab nrog daim nyias nyias tiv thaiv).
Cov Tshuaj Pharmacokinetics
Acetylsalicylic acid muaj qhov nqus dej siab. Tom qab kev tswj hwm ntawm qhov ncauj, nws nrawm rau hauv lub plab thiab ncav cuag nws qhov ntshav siab tshaj plaws tom qab 1-2 teev. Thaum noj cov tshuaj nrog zaub mov, nqus tuaj poob qis. Lub bioavailability ntawm cov kua qaub no yog 80-90%. Nws tau faib nyob thoob hauv lub cev, kis mus rau niam mis thiab dhau ntawm qhov txwv.
Thawj qhov kev paub tshwm sim hauv lub plab.
Thawj qhov kev paub tshwm sim hauv lub plab. Hauv qhov no, salicylates yog tsim. Kev metabolism ntxiv yog nqa tawm hauv daim siab. Salicylates raug cais tawm los ntawm lub raum tsis hloov pauv.
Magnesium hydroxide muaj qhov nqus dej tsawg thiab ua kom tsis tshua muaj bioavailability (25-30%). Nws kis tau rau hauv niam cov kua mis hauv me me thiab hla tsis zoo los ntawm qhov tsis muaj qhov thaiv. Magnesium yog tawm ntawm lub cev tsuas yog nrog quav.
Dab tsi yog nws rau?
Cov tshuaj tau muab tshuaj rau cov kab mob nram qab no:
- Mob plawv thiab mob ntsws (mob plawv).
- Tsis ruaj tsis khov angina pectoris.
- Mob Siab.
Cov tshuaj yog tawm rau cov kab mob plawv.
Cov tshuaj yog raug rau cov pob ntseg tsis khov.
Cov tshuaj yog tawm rau cov mob thrombosis.
Cov tshuaj yog feem ntau siv los tiv thaiv kom tsis txhob muaj thromboembolism (tom qab kev phais mob), mob plawv tsis txaus, myocardial infarction thiab cerebrovascular huam yuaj. Cov neeg mob uas mob ntshav qab zib mellitus, kub siab, mob ntshav siab, nrog rau cov neeg haus luam yeeb tom qab 50 xyoo, xav tau kev tiv thaiv zoo ib yam.
Yuav ua li cas noj Cardiomagnyl Forte?
Cov tshuaj yog coj qhov ncauj nrog me ntsis dej. Cov ntsiav tshuaj muaj peev xwm raug faib ua 2 ntu (nrog kev pabcuam ntawm kev pheej hmoo) lossis zuaj kom nqus tau sai.
Txhawm rau kom tshem tawm qhov mob ntshav siab ntawm cov mob ntsig txog mob plawv, 1 ntsiav tshuaj ib hnub (150 mg ntawm acetylsalicylic acid) yog tshuaj. Cov tshuaj no yog pib ua ntej. Tom qab ntawd nws raug txo los ntawm 2 zaug.
Tom qab phais vascular, 75 mg (ib nrab ntawm ib ntsiav tshuaj) lossis 150 mg tau noj nyob ntawm kev txiav txim siab ntawm tus kws kho mob.
Txhawm rau tiv thaiv cov kab mob plawv (myocardial infarction, thrombosis) noj ib nrab ib ntsiav tshuaj ib hnub.
Noj cov tshuaj rau ntshav qab zib
Cov neeg mob ntshav qab zib muaj feem yuav ua rau muaj ntshav nce ntxiv thiab txhim kho cov mob thrombosis. Rau lub hom phiaj ntawm kev tiv thaiv, ib nrab ntawm ib ntsiav tshuaj yog teem rau ib hnub.
Cov neeg mob ntshav qab zib muaj feem yuav ua rau muaj ntshav nce ntxiv thiab txhim kho cov mob thrombosis. Rau lub hom phiaj ntawm kev tiv thaiv, ib nrab ntawm ib ntsiav tshuaj yog teem rau ib hnub.
Hematopoietic plab hnyuv siab raum
Kev kho cov ntshav khov muaj qhov pheej hmoo ntawm kev tsim:
- anemia
- thrombocytopenia
- neutropenia
- agranulocytosis,
- eosinophilia.
Los ntawm kev noj cov tshuaj, qhov tshwm sim zoo li txoj hlab pas tuaj yeem tshwm sim.
Ib qho kev tshwm sim xws li xeev siab thiab ntuav tuaj yeem tshwm sim los ntawm kev noj cov tshuaj.
Los ntawm kev noj cov tshuaj, ib qho kev tshwm sim tuaj yeem tshwm sim los ntawm tus mob bronchospasm.
Los ntawm kev noj cov tshuaj, qhov tshwm sim ib yam li raws plab yuav tshwm sim.
Los ntawm kev noj cov tshuaj, qhov tshwm sim ib yam li stomatitis tuaj yeem tshwm sim.
Ib qho kev mob tshwm sim zoo li eosinophilia tuaj yeem tshwm sim los ntawm kev noj cov tshuaj.
Los ntawm kev noj cov tshuaj, qhov tshwm sim zoo ib yam li urticaria tuaj yeem tshwm sim.
Qee zaum cov kev tsis haum tshuaj xws li:
- Quincke's edema,
- khaus tawv
- urticaria
- spasm ntawm lub bronchi.
Siv thaum cev xeeb tub thiab lactation
Cov tshuaj tau pom zoo rau kev siv nyob rau 2 hlis thib ntawm cev xeeb tub ntawm kev pom zoo los ntawm cov kws tshwj xeeb. Tus kws kho mob tuaj yeem sau tshuaj rau cov tshuaj no thaum cov txiaj ntsig rau leej niam outweighs qhov kev pheej hmoo rau cov menyuam hauv plab.
Hauv thawj peb lub hlis thaum cev xeeb tub, Cardiomagnyl tuaj yeem ua rau tus me nyuam hauv plab tsis zoo. Nws yog txwv tsis pub siv tshuaj nyob rau hauv koob thib 3. Nws inhibits kev ua haujlwm thiab ua kom muaj kev pheej hmoo los ntshav hauv niam thiab menyuam.
Salicylates kis mus rau niam cov kua mis hauv ib qho me me. Thaum pub niam mis, cov tshuaj yog siv nrog ceev faj (ib qho tshuaj yog tso cai yog tias tsim nyog). Kev siv tshuaj ntev ntev tuaj yeem tsim kev puas tsuaj rau tus menyuam.
Daim ntawv thov rau lub raum khiav tsis zoo
Txij li thaum nthuav tawm ntawm salicylates yog nqa tawm los ntawm ob lub raum, nyob rau hauv muaj lub raum tsis ua haujlwm, cov tshuaj yuav tsum tau ua nrog ceev faj. Nrog rau lub raum ua mob hnyav, tus kws kho mob yuav txwv tsis pub noj cov tshuaj no.
Txij li thaum nthuav tawm ntawm salicylates yog nqa tawm los ntawm ob lub raum, nyob rau hauv muaj lub raum tsis ua haujlwm, cov tshuaj yuav tsum tau ua nrog ceev faj.
Kev cuam tshuam nrog lwm yam tshuaj
Cov tshuaj no tsis pom zoo siv rau hauv kev sib xyaw nrog lwm cov NSAIDs. Qhov kev sib txuam no ua rau nce kev ua yeeb yam ntawm cov tshuaj thiab cov kev mob tshwm sim ntxiv.
Cardiomagnyl kuj txhim kho qhov kev txiav txim:
- tshuaj thaiv tsev
- Tshuaj Acetazolamide
- Methotrexate
- cov kab mob hypoglycemic.
Muaj qhov txo qis hauv qhov kev nqis tes ua ntawm diuretics xws li Furosemide thiab Spironolactone. Nrog rau kev tswj hwm tib lub sijhawm nrog Colestiramine thiab antacids, tus nqi ntawm kev nqus ntawm Cardiomagnyl poob qis. Kev txo qis hauv kev ua tau zoo kuj muaj tshwm sim thaum ua ke nrog probenecid.
Cawv tau zoo
Haus dej cawv thaum kho txoj kev kho yog txwv tsis pub. Cawv ua rau cov nyhuv ntxaum ntawm cov ntsiav tshuaj ntawm lub plab zom mov mucosa. Qhov no nce qhov kev pheej hmoo ntawm phiv.
Cov tshuaj uas nrov nrog cov nyhuv zoo sib xws yog Aspirin Cardio, Thrombital, Acekardol, Magnikor, Thrombo-Ass.
Cardiomagnyl | cov lus qhia rau siv Aspirin Cardio cov lus qhia Thrombital Forte cov lus qhia Thrombo ACC cov lus qhia
Cardiomagnyl Fort tshuaj xyuas
Igor, 43 xyoo, Krasnoyarsk.
Kuv tau ua tus kws kho plawv ntev tau 10 lub xyoo. Kuv xaj tshuaj cardiomagnylum rau ntau tus neeg mob. Nws muaj cov nyhuv nrawm, muaj tus nqi pheej yig thiab muaj qee qhov cuam tshuam. Cov tshuaj yog yam tsis tseem ceeb rau kev tiv thaiv lub plawv thiab mob plawv.
Alexandra, 35 xyoo, Vladimir.
Kuv muab cov tshuaj no rau cov neeg mob tom qab 40 xyoo rau kev tiv thaiv cov kab mob ntawm cov hlab plawv. Txhua tus neeg mob zam nws tau zoo. Hauv kev coj ua, Kuv tsis pom ib qho tshwm sim dabtsi. Tab sis kuv qhia koj tsis txhob coj nws tus kheej thiab kev tswj tsis tau.
Victor, 46 xyoo, Zheleznogorsk.
Cardiomagnyl yog qhov yooj yim siv, pheej yig thiab muaj kev nyab xeeb. Kuv pom zoo cov tshuaj rau cov neeg mob ua mob plawv, mob hlab ntsha hauv lub hlwb, mob hlab ntsha tsis muaj ntshav thiab mob thos. Kuv nquag sau ntawv rau nws rau kev tiv thaiv lub hom phiaj.
Anastasia, 58 xyoo, Ryazan.
Kuv pheej noj cov ntsiav tshuaj no tom qab lub plawv nres rau kev pom zoo ntawm kws kho mob. Cov tshuaj tau zoo tiv thaiv, tsis muaj kev phiv. Txij thaum pib ntawm kev txais tos kuv tam sim ntawd zoo dua.
Daria, 36 xyoo, St. Petersburg.
Kuv haus cov tshuaj no raws li kws kho mob tau sau tseg rau kev kho mob ntawm cov ntshav ua pa. Cov tshuaj dilutes ntshav thiab tiv thaiv cov ntshav txhaws. Kuv tau mob, ceg hnyav thiab mob ntswj thaum hmo ntuj. Zoo tshuaj!
Gregory, hnub nyoog 47 xyoo, Moscow.
Kuv tau mob plawv 2 xyoo dhau los. Tam sim no kuv tab tom noj cov tshuaj no rau kev tiv thaiv. Nws xav tias zoo thiab tsis muaj kev phiv. Kuv kuj tau tshem ntawm qhov mob taub hau tas mus li.