Kev tiv thaiv thaum muaj xwm ceev-insulin: cov lus qhia rau kev siv

Yog tias koj cev xeeb tub lossis npaj ua kom cev xeeb tub, koj yuav tsum tau sab laj nrog kws kho mob tam sim ntawd los tham txog qhov yuav tsum tau txhaj tshuaj insulin li cas thiaj yuav tau them cov ntshav qab zib kom tsis txhob thiab zam dhau hyperglycemia (ntshav qab zib dhau) thiab ntshav qab zib tsawg (ntshav qab zib qis heev), txij li ob qho ntawm cov mob no tuaj ua mob rau koj tus menyuam hauv plab. Kev pub niam mis thaum kho cov tshuaj insulin tsis muaj kev phom sij rau koj tus menyuam. Txawm li cas los xij, nws muaj peev xwm tias qhov koob tshuaj insulin thiab khoom noj haus yuav tsum tau kho.

Tsuas tshuaj thiab tswj hwm

ES protamine-insulin yog npaj rau kev tswj hwm ntawm subcutaneous. Cov tshuaj tsis tuaj yeem muab tshuaj hla dej.

Cov koob tshuaj ntawm cov tshuaj yog txiav txim los ntawm tus kws kho mob tshwj xeeb hauv txhua kis raws qhov theem ntawm cov piam thaj hauv cov ntshav. Qhov nruab nrab, kev siv tshuaj txhua hnub los ntawm 0.5 mus rau 1 IU / kg lub cev qhov hnyav, nyob ntawm tus neeg ntawd tus yam ntxwv ntawm tus neeg mob thiab theem ntawm cov ntshav nyob hauv lub cev.

Qhov kub ntawm cov tshuaj insulin yuav tsum nyob ntawm chav sov.

ES protamine-insulin feem ntau yog txhaj tshuaj subcutaneously rau hauv tus ncej puab. Thaum muab tshuaj subcutaneously rau hauv tus ncej puab, cov tshuaj yuav nqus qeeb dua thiab ntau dua tusyees dua li thaum txhaj rau lwm qhov chaw.

Kev hno tuaj yeem ua tau nyob hauv thaj av ntawm deltoid leeg ntawm lub xub pwg.

Ua kev txhaj tshuaj rau hauv cov tawv nqaij txo qhov kev pheej hmoo ntawm kev nkag mus rau hauv cov leeg nqaij. Nws yog ib qho tsim nyog yuav tsum hloov chaw txhaj tshuaj nyob rau hauv thaj chaw anatomical thiaj li tiv thaiv kev txhim kho ntawm lipodystrophy.

Nrog rau kev siv tshuaj insulin ntau, Protamine-Insulin Cov xwm txheej ceev tuaj yeem siv tshuaj insulin basal 1-2 zaug hauv ib hnub (yav tsaus ntuj thiab / lossis thawj coj thaum sawv ntxov) nrog cov tshuaj insulin luv luv, uas tau tswj ua ntej noj mov.

Hauv hom 2 mob ntshav qab zib mellitus, Protamine-Insulin Xwm ceev tuaj yeem siv nrog kev sib xyaw nrog hypoglycemic tshuaj noj ntawm qhov ncauj thaum muaj kev tswj hwm tus kheej ntawm cov tshuaj no tsis them nyiaj rau cov ntshav qab zib mellitus.

Pharmacological kev txiav txim

Qhov nruab nrab-ncua sij hawm tib neeg cov insulin tau siv siv DNA thev naus laus zis sib zog. Nws cuam tshuam nrog kev tsim tshwj xeeb nyob rau sab nraud cytoplasmic membrane ntawm cov hlwb thiab tsim cov txheej txheem insulin-receptor complex uas txhawb cov txheej txheem intracellular, suav nrog

synthesis ntawm cov naj npawb ntawm cov enzymes tseem ceeb (hexokinase, pyruvate kinase, glycogen synthetase). Cov thawj coj hauv cov ntshav nyob rau hauv lub cev vim qhov nce ntawm nws txoj kev thauj mus los rau hauv lub cev ntau dua ntxiv, ntau dua qhov kev nqus thiab kev ua haujlwm ntawm cov nqaij mos, ua kom lub ntsej muag lipogenesis, glycogenogenesis, thiab txo tus nqi ntawm cov piam thaj los ntawm lub siab.

Lub sijhawm ntawm cov kev ua ntawm insulin npaj feem ntau vim yog tus nqi ntawm kev nqus, uas nyob ntawm ntau yam (piv txwv li, ntawm koob tshuaj, txoj kev thiab qhov chaw ntawm cov thawj coj), thiab yog li cov ntaub ntawv ntawm kev ua ntawm insulin yog raug rau qhov txawv txav, ob leeg hauv cov neeg sib txawv thiab tib tus neeg.

Qhov nruab nrab, tom qab kev tswj hwm sc, qhov tshuaj insulin pib ua haujlwm tom qab 1.5 teev, qhov ua haujlwm siab tshaj plaws tsim tawm ntawm 4 teev mus rau 12 teev, sijhawm ua haujlwm tau ntev txog 24 teev.

Cov Tshuaj Pharmacokinetics

Kev ua tiav ntawm kev nqus thiab pib ntawm cov nyhuv ntawm cov tshuaj insulin nyob ntawm qhov chaw txhaj tshuaj (plab, ncej, pob tw), qhov koob tshuaj (ntim ntawm txhaj tshuaj insulin), thiab qhov tob ntawm cov tshuaj insulin hauv kev npaj.

Nws tau faib qhov tsis sib luag thoob plaws cov ntaub so ntswg, tsis txeem rau hauv qhov chaw nres thiab nkag mus rau niam mis. Nws yog rhuav tshem los ntawm insulinase feem ntau hauv daim siab thiab lub raum. Nws yog tawm los ntawm lub raum (30-80%).

Hom 1 mob ntshav qab zib mellitus, hom 2 mob ntshav qab zib mellitus: theem ntawm kev tawm tsam cov tshuaj tiv thaiv kab mob hauv lub qhov ncauj, tiv taus ib feem ntawm cov tshuaj no (thaum kho sib txuam), cov kab mob sib kis, hom 2 mob ntshav qab zib mellitus hauv cov poj niam cev xeeb tub.

Cov Yuav Tsum Tau Ua

Kev mob ntshav qab zib ntau ntau, nce ib leeg ib leeg rhiab rau insulin.

Rau kev tswj hwm sc xwb. Cov koob tshuaj ntawm cov tshuaj tau txiav txim siab los ntawm tus kws kho mob tshwj xeeb hauv txhua kis, raws li kev mloog zoo ntawm cov piam thaj hauv cov ntshav.

Qhov nruab nrab, koob tshuaj txhua hnub los ntawm 0.5 mus rau 1 IU / kg lub cev qhov hnyav (nyob ntawm tus neeg qhov yam ntxwv ntawm tus neeg mob thiab cov concentration ntawm cov ntshav qab zib).

Sab vim los ntawm cov nyhuv rau cov metabolism hauv carbohydrate: hypoglycemic tej yam kev mob (pallor ntawm daim tawv nqaij, nce tawm hws, palpitations, tshee tshee, tshaib plab, ntxhov siab, lub plab ntawm lub qhov ncauj, mob taub hau, kiv taub hau, tsis pom kev zoo nkauj). Kev mob ntshav qog ntshav qis tuaj yeem ua rau txhim kho kev mob hypoglycemic coma.

Kev tsis haum tshuaj: tawv nqaij ua pob, Quincke's edema, anaphylactic poob siab.

Cov tshuaj tiv thaiv hauv zos: hyperemia, o thiab khaus ntawm qhov chaw txhaj tshuaj, nrog rau siv sijhawm ntev - lipodystrophy ntawm thaj chaw txhaj tshuaj.

Lwm yam: o, cov txav zuj zus hauv qhov pom tseeb (feem ntau thaum pib kho).

Yeeb tshuaj sib cuam tshuam

Hypoglycemic nyhuv ntawm insulin txhim khu qhov ncauj hypoglycemic tshuaj, Mao inhibitors, ACE inhibitors, carbonic anhydrase inhibitors, xim beta-blockers, bromocriptine, octreotide, sulfonamides, anabolic steroids, tetracyclines, clofibrate, ketoconazole, mebendazole, pyridoxine, theophylline, cyclophosphamide, fenfluramine, lithium npaj npaj muaj ethanol.

Cov nyhuv hypoglycemic ntawm insulin yog attenuated los ntawm glucagon, somatropin, estrogens, tshuaj tiv thaiv qhov ncauj, corticosteroids, iodine-muaj cov thyroid hormones, thiazide diuretics, "loop" diuretics, heparin, tricyclic antidepressants, sympathomimetics, corticosteroids, iodine-muaj cov thyroid hormones, thiazide diuretics, "loop" diuretics, heparin, tricyclic antidepressants, sympathomimetics, danazole, clonidine receptors, calininsine receptors , diazoxide, morphine, phenytoin, nicotine.

Hauv qab ntawm reserpine thiab salicylates, ob qho tib si qaug zog thiab txhim kho kev ua ntawm insulin yog ua tau.

Txo kom tsis txaus siab rau ethanol.

Cov lus qhia tshwj xeeb

Tawm tsam tom qab ntawm cov tshuaj insulin, kev tshuaj xyuas cov ntshav qabzib hauv siab yog qhov tsim nyog.

Cov laj thawj ntawm cov ntshav qog ntshav ntshav ntxiv rau kev noj tshuaj insulin ntau tshaj tuaj yeem yog: hloov tshuaj, hla zaub mov, ntuav, raws plab, ua kom lub cev muaj zog ntau ntxiv, cov kab mob uas txo qis qhov xav tau rau insulin (kev mob siab rau lub siab thiab lub raum kev ua haujlwm, kev ua haujlwm ntawm adrenal cortex, pituitary lossis thyroid caj pas), hloov chaw txhaj tshuaj, ntxiv rau kev cuam tshuam nrog rau lwm cov tshuaj.

Kev noj tshuaj tsis yog lossis cuam tshuam rau hauv cov tshuaj insulin, tshwj xeeb tshaj yog nyob rau cov neeg mob ntshav qab zib hom 1, tuaj yeem ua rau mob hyperglycemia. Feem ntau thawj cov tsos mob ntawm hyperglycemia pib maj mam dhau ob peb teev lossis hnub.

Cov no suav nrog kev nqhis dej, tso zis tsis tu ncua, xeev ntuav, ntuav, kiv taub hau, liab thiab ntawm daim tawv nqaij, qhov ncauj qhuav, tsis qab los, tsis hnov ntxhiab ntawm cov acetone hauv cov pa tawm.

Yog tias tsis kho, hyperglycemia hauv ntshav qab zib hom 1 tuaj yeem ua rau muaj kev tiv thaiv cov mob ntshav qab zib ketoacidosis.

Cov koob tshuaj cov tshuaj insulin yuav tsum tau kho nyob rau hauv kev txiav txim siab ntawm lub qog ua haujlwm tsis txaus, Addison's disease, hypopituitarism, ua rau lub siab thiab lub raum tsis ua haujlwm, thiab mob ntshav qab zib mellitus hauv cov neeg mob uas muaj hnub nyoog 65 xyoos.

Hauv kev pom ntawm kev pheej hmoo ntawm lub plawv mob thiab lub hlwb ntawm lub qog ntshav qab zib, cov tshuaj insulin yuav tsum tau siv nrog ceev faj hauv cov neeg mob uas mob hnyav ntawm cov hlab ntshav ntawm lub plawv thiab cov hlab ntsha txhaws.

Nrog faj seeb nyob rau hauv cov neeg mob proliferative retinopathy, tshwj xeeb tsis tau txais kev kho mob nrog photocoagulation (laser coagulation) vim muaj kev pheej hmoo ntawm amaurosis (ua tiav dig muag).

Yog tias tus neeg mob ua kom lub cev ua hauj lwm ntau ntxiv lossis hloov cov zaub mov ib txwm noj, yuav tsum tau txhaj tshuaj insulin kom haum.

Cov kab mob sib xyaw tshwj xeeb, tshwj xeeb tshaj yog kis mob thiab cov kab mob nrog kub taub hau, nce ntxiv qhov xav tau ntawm insulin.

Kev hloov chaw ntawm tus neeg mob mus rau ib hom tshiab ntawm insulin lossis kev npaj tshuaj insulin ntawm lwm qhov chaw tsim khoom yuav tsum tau ua nyob rau hauv kev saib xyuas ntawm tus kws kho mob.

Thaum siv cov tshuaj insulin nyob rau hauv kev sib xyaw nrog cov tshuaj ntawm thiazolidinedione pab pawg, cov neeg mob uas muaj ntshav qab zib hom 2 mob ntshav qab zib yuav muaj kev tso dej tawm, uas ua rau muaj kev pheej hmoo ntawm kev txhim kho thiab kev txhim kho mob plawv tsis ua haujlwm, tshwj xeeb tshaj yog nyob rau cov neeg mob uas muaj kab mob ntawm cov hlab plawv thiab muaj cov kev pheej hmoo rau mob ntev lub plawv tsis ua hauj lwm. Cov neeg mob uas tau txais kev kho mob zoo li no yuav tsum tau kuaj xyuas tsis tu ncua kom pom cov cim ntawm lub plawv tsis ua haujlwm. Yog tias lub plawv tsis ua haujlwm tshwm sim, txoj kev kho yuav tsum ua raws li cov qauv kev kho mob tam sim no. Hauv qhov no, nws yog ib qho tsim nyog los xav txog kev ncua lossis txo qhov txo cov thiazolidinedione.

Cev xeeb tub thiab lactation

Tsis muaj kev txwv rau kev kho mob ntshav qab zib mellitus nrog cov tshuaj insulin thaum cev xeeb tub, vim hais tias cov tshuaj insulin tsis hla qhov chaw tiv thaiv. Thaum npaj kev cev xeeb tub thiab thaum nws, nws yog ib qho tsim nyog yuav tsum tau ua ntu zus ntawm kev kho mob ntshav qab zib. Qhov kev xav tau rau insulin feem ntau poob qis hauv thawj peb lub hlis thaum cev xeeb tub thiab maj mam nce ntxiv hauv qib thib ob thiab thib peb.

Thaum lub sijhawm thiab yug tom qab yug, insulin yuav tsum poob ntau. Tsis ntev tom qab yug los, xav tau cov tshuaj insulin sai sai rau qib uas yog ua ntej cev xeeb tub.

Kev piav qhia ntawm cov tshuaj PROTAMIN-INSULIN ES yog ua raws li cov lus qhia raug pom zoo rau kev siv thiab pom zoo los ntawm cov kws tsim khoom.

Pom muaj kab laum? Xaiv nws thiab nias Ctrl + Enter.

PROTAMIN-INSULIN CHS 100ME / ML 10ML SUSP P / K FLAK

Qhov kev ncua yog dawb. Thaum sawv ntsug, qhov kev ncua tawm delaminates los ua cov xim tsis muaj xim lossis yuav luag tsis muaj xim supernatant thiab muaj dej nag sai sai, uas yuav muaj cov clog uas yooj yim resuspended nrog nplawm.

1 ml ntawm cov tshuaj muaj: cov tshuaj nquag: tib neeg cov tshuaj lom neeg cov tshuaj insulin 100 IU,

kev zam: cov tshuaj protamine sulfate 0.35 mg, sodium hydrogen phosphate dihydrate 2.4 mg, zinc chloride 0.018 mg, phenol 0.65 mg, metacresol 1.5 mg, glycerol (glycerin) 16.0 mg, dej rau kev txhaj tshuaj txog li 1 ml Cov.

PROTAMIN-INSULIN HS (PROTAMIN-INSULIN HS)

Tawm tsam keeb kwm yav dhau los ntawm kev kho mob insulin, kev tshuaj xyuas cov ntshav qabzib ntau yog tsim nyog.

Cov laj thawj ntawm cov ntshav qog ntshav ntshav ntxiv rau kev noj tshuaj insulin ntau tshaj tuaj yeem yog: hloov tshuaj, hla zaub mov, ntuav, raws plab, kev ntxhov siab ntawm lub cev, cov kab mob uas txo qis qhov xav tau rau insulin (kev mob siab rau lub siab thiab lub raum kev ua haujlwm, kev ua haujlwm ntawm adrenal cortex, pituitary lossis thyroid caj pas), thiab hloov chaw txhaj tshuaj, thiab kuj cuam tshuam nrog lwm cov tshuaj.

Kev noj tshuaj tsis zoo los yog cuam tshuam hauv kev tswj hwm insulin, tshwj xeeb tshaj yog nyob rau cov neeg mob ntshav qab zib hom 1, tuaj yeem ua rau mob hyperglycemia. Feem ntau, thawj cov tsos mob ntawm hyperglycemia pib maj mam dhau ob peb teev lossis hnub.

Cov no suav nrog kev nqhis dej, ntxiv tso zis, xeev ntuav, ntuav, kiv taub hau, liab thiab ntawm daim tawv nqaij, qhov ncauj qhuav, tsis qab los, tsis hnov ntxhiab ntawm cov acetone hauv cov pa tawm.

Yog tias tsis kho, hyperglycemia hauv ntshav qab zib hom 1 tuaj yeem ua rau muaj kev tiv thaiv cov mob ntshav qab zib ketoacidosis.

Cov koob tshuaj insulin yuav tsum raug kho rau kev ua haujlwm ntawm cov thyroid uas tsis ua haujlwm, Addison's disease, hypopituitarism, ua rau lub siab thiab lub raum tsis ua haujlwm thiab mob ntshav qab zib hauv cov neeg laus laus dua 65 xyoos.

Cov kab mob sib xyaw tshwj xeeb, tshwj xeeb tshaj yog kis mob thiab cov kab mob nrog kub taub hau, nce ntxiv qhov xav tau ntawm insulin.

Kev kho tshuaj ntawm cov tshuaj insulin kuj tseem xav tau yog tias tus neeg mob nce qib qoj ib ce lossis hloov cov zaub mov ib txwm muaj.

Txoj kev hloov ntawm ib hom lossis hom tshuaj ntshav dej rau lwm qhov yuav tsum tau ua nyob rau kev saib xyuas ntawm tus kws kho mob nruj. Kev hloov pauv hauv kev xav, hom tshuaj npe (chaw tsim khoom), hom (luv luv, nruab nrab thiab ntev ua yeeb yam insulin, thiab lwm yam)

), hom (tib neeg, tsiaj) thiab / lossis cov qauv kev tsim tawm (tsiaj los yog tshuaj tua tsiaj genetic) yuav xav tau koob tshuaj los kho cov tshuaj insulin.

Qhov xav tau tshuaj no ntawm cov tshuaj insulin tuaj yeem tshwm sim tom qab thov thawj zaug, thiab thawj ob peb lub lis piam lossis ob hlis.

Thaum hloov los ntawm tsiaj los ntawm cov tshuaj insulin rau ES-Protamine-insulin, qee cov neeg mob tau sau tseg hloov lossis tsis muaj zog ntawm cov tsos mob ntawm cov tshwm sim ntawm kev txo ntshav siab.

Thaum raug mob zoo rau kev noj haus metabolism hauv kev lom zem, piv txwv li, vim tias muaj zog los kho cov tshuaj insulin, cov tsos mob li ib txwm muaj ntawm kev txo qis ntawm hypoglycemia kuj tuaj yeem hloov pauv, hais txog tus neeg mob twg yuav tsum ceeb toom.

Cov neeg muaj mob plawv tsis txaus siab tau tshaj tawm nrog kev siv cov tshuaj insulin thiab thiazolidinediones, tshwj xeeb tshaj yog nyob rau cov neeg mob uas muaj feem cuam tshuam rau lub plawv tsis ua haujlwm. Qhov no yuav tsum tau ris hauv siab thaum muab qhov kev sib xyaw no.

Yog tias kev sib xyaw saum toj no tau sau tseg, nws yog qhov yuav tsum tau ua kom paub cov cim thiab cov tsos mob ntawm lub plawv tsis ua haujlwm, nce phaus, edema. Kev siv cov pioglitazone yuav tsum nres yog tias cov tsos mob ntawm cov hlab plawv mob tuaj.

Cuam tshuam rau kev muaj peev xwm tsav tsheb thiab tswj cov tshuab

Lub peev xwm ntawm cov neeg mob kom pom tseeb thiab tus nqi tshuaj tiv thaiv tej zaum yuav raug mob thaum lub sijhawm hypoglycemia thiab hyperglycemia, uas tuaj yeem ua rau muaj kev phom sij, piv txwv li, thaum tsav tsheb lossis ua haujlwm nrog cov tshuab thiab tshuab.

Cov neeg mob yuav tsum tau qhia rau kev ntsuas kom tiv thaiv kev txhim kho hypoglycemia thiab hyperglycemia thaum tsav tsheb thiab ua haujlwm nrog cov txheej txheem.

Qhov no tseem ceeb tshwj xeeb tshaj yog rau cov neeg mob uas tsis muaj los yog tsawg dua cov tsos mob ntawm kev tsim kho tus mob hypoglycemia lossis raug mob los ntawm kev pheej muaj ntshav ntau ntawm cov ntshav siab. Hauv cov xwm txheej zoo li no, kev tsim nyog ntawm kev tsav tsheb yuav tsum xav txog.

Kev tiv thaiv thaum muaj xwm ceev-insulin: cov lus qhia rau kev siv

Kev noj tshuaj rau tus kheej tuaj yeem tsim kev phom sij rau koj kev noj qab haus huv.
Nws yog ib qho tsim nyog yuav tsum sab laj tus kws kho mob, nrog rau nyeem cov lus qhia ua ntej siv.

Kev sib xyaw rau ib 1 ml: cov tshuaj nquag: kev tshuaj ntsuam genetic engineering tib neeg cov kua dej - 100 ME, tus zam: protamine sulfate, disodium phosphate dihydrate, zinc chloride, phenol, metacresol, glycerin, dej rau kev txhaj tshuaj.

kev ncua rau kev txhaj tshuaj 100 IU / ml.

Ua hauv Belarus - lub neej ntawm insulin peaks

Svetlana KAZACHONOK, Minsk, hom I mob ntshav qab zib kev paub - 45 xyoo

Kev ua tiav hauv kev kho mob ntshav qab zib nyob ntawm ntau yam, tab sis ib qho tseem ceeb tshaj plaws yog muaj cov tshuaj insulin zoo. Qhov no yog qhov kuv tus kheej xaus, raws li 45 xyoo ntawm kev paub - los ntawm 12 xyoo, los ntawm txoj kev deb 1963, Kuv yuav tsum kho kuv txoj hmoo thiab tsim kuv lub neej nyob hauv "qhov muaj zog" ntawm insulin kev ua ...

Kuv kawm tiav hauv tsev kawm, tsev kawm qib siab, thiab tau ntau xyoo ua haujlwm ntawm Minsk Porcelain Factory. Mob ntshav qab zib yuav luag tsis ua rau kuv tsis muaj kev xyiv fab hauv lub neej, nws tsuas yog los ua txhua hnub. Tab sis cov lus nug ntawm cov tshuaj insulin tau ib txwm mob.

Ib yam li cov mob ntshav qab zib los ntawm lub xyoo pua xeem, Kuv tau sim ntau yam sib txawv - nqaij npuas, nqaij nyug, kev tsim hluav taws xob. Hauv tsev kawm xyoo nws tau txais ib qho zoo tshaj plaws ntawm lub sijhawm ntawd - insulin-B. Tab sis kom txog thaum nws yoog nws, tsis tau txais kev paub, kev kho mob tsim muaj ntau yam teeb meem.

Tom qab ntawd cov tshuaj insulin no ploj, lwm tus tshwm sim - ICCA (amorphous zinc - insulin ncua). Nws tso qhov kev txaus siab tshaj plaws - mob taub hau, xeev siab, kev nyuaj siab. Twb kawm nyob rau hauv BPI, nws tau nyob hauv tsev kho mob ob peb zaug vim kev nkag tsis tau rau ICCA.

Tom qab ntawd nws tau hloov nrog tshuaj protamine - zinc - insulin hauv kev sib xyaw ua ke nrog yooj yim, thiab rov qab muaj suab thaj tsis zoo, lub taub hau mob, thiab xeev siab. Rhuav hluas. Nrog lub caij nyoog dhau los ntawm monotard, nws zoo siab dua, tab sis cov teeb meem tshwm sim. Thiab cov monotard tsis tseg.

Cov xwm txheej ntawm kev mus ntsib tus kws endocrinologist hauv 80s tau yooj yim heev: tus kws kho mob tshaj tawm kev ua tiav ntawm kev tsim tshuaj insulin (mob siab heev), thiab kuv tau xaiv ntau dua. Nws tau sim ntau zaus kom hloov mus rau Belarusian insulin, tab sis tsis muaj qhov cuam tshuam. Txawm tias qhov nce ntxiv rau koob tshuaj tsis ua rau muaj kev txo qis li qub.

Txij lub hli mus rau ze li 25 xyoo, Kuv tsis paub tias yuav muaj cov tshuaj insulin twg tom qab. Tab sis nws tsis tau xav tias muaj dab tsi tom ntej.

Lub sij hawm nyuaj siab tshaj plaws rau Belarusian cov ntshav qab zib yog thaum lub xyoo perestroika. Xyoo 1996, mob leapfrog nrog cov tshuaj insulin, Kuv pib muaj mob txha caj qaum, kuv pw hauv tsev kho mob txog 3 hlis. Cov kws kho mob tau sim, tab sis tsis tuaj yeem nres qhov kev kis mob.

Nws tsis tuaj yeem taug kev ntxiv lawm, nws tau qw hauv kev mob, nws txhais ceg tig mus rau hauv lub cav, thiab txog li ib xyoos nws kub. Txoj kev cawm seej yog los ntawm ib tug phooj ywg uas coj tawm qhov zoo ntawm cov tshuaj insulin thiab ib qho khoom plig pleev nrog cov ntawv ntsuas.

Kev tswj cov piam thaj, tsis tso cai rau nws cov txiaj ntsig saum 7-8 mmol / l, nws tau ua tiav, tau txais nws ob txhais taw.

Kuv tseem nco qab Lub Rau Hli 2001, thaum lub sijhawm teem sijhawm nrog endocrinologist hauv kuv lub chaw kuaj mob Kuv pom tias tsis muaj cov tshuaj insulin rau cov neeg mob txhua. Nrog txoj kev nyuaj nws rub nws tus kheej ua ke, txwv tsis pub muaj kev cia siab (zoo li nws yog, tus muam tau nyob hauv tsev tom qab ua haujlwm nyuaj, nws xav tau kuv kev pab). Cov phooj ywg dua tau pab.

Txij thaum ntawd los, kuv tau nres mus ntsib tus kws kho mob thiab tau txais kev kho mob ntawm nws tus kheej. Kuv hloov mus rau ntau qhov kev txhaj tshuaj, kis tau cov tshuaj insulins hauv cov chaw muag tshuaj. Tab sis qhov kawg ntawm xyoo 2008. Thiab muaj kev cuam tshuam nrog lawv hauv Minsk.

Kuv yuav tsum tau tig mus rau hauv lub nroog faib, qhov chaw uas lawv tau qhia kuv txog cov tshuaj tua kab mob ntawm cov roj ntsha tshiab hauv Belarusian thiab muab kev sim.

Txij li kuv tsis tas yuav tsum xaiv, Kuv pom zoo, txawm li cas los xij, tsis muaj yam txaus siab.

Hnub tom qab, Belarusian insulins tau pib txhaj tshuaj. Cov koob tshuaj yav dhau los tseem tsis tau hloov pauv. Ib lub lis piam dhau mus, ob, peb ... Kuv tsis tas yuav kho cov koob tshuaj, vim

cov ntshav qab zib cov cim yog zoo ib yam rau cov neeg muaj yeeb tshuaj txawv teb. Piv txwv li, 10 lub hlis nyob ntawm insulin txo qis kuv cov piam thaj li ntawm 3 mmol / L, zoo ib yam tshwm sim nrog ES protamine - insulin.

Tsis muaj qhov tshwm sim tsis zoo (mob taub hau, xeev siab) tshwm sim. Kuv xav tias zoo.

Puas yog lawm tiag?! High-quality noob insulin ntawm kev tsim tawm hauv tsev tau tshwm sim! Tom qab txhua qhov, qhov no txhais tau hais tias ntau tus neeg mob ntshav qab zib ntawm peb cov koom pheej yuav tau kho raws li ib txwm ua, siv lawv cov phiaj xwm thiab tsis tuag ua ntej ntawm cov teeb meem.

Kuv thov ua tsaug ntau rau cov neeg uas tswj hwm los siv ua qhov haujlwm tseem ceeb no. Thaum kawg, tus mob ntshav qab zib tau xav txog kev saib xyuas ntawm lub xeev. Ib kauj ruam hauv peb txoj kev taw qhia tau ua tiav, Kuv vam tias tsis yog tus kawg!

PEB SAIB

Belarusian kws tshuaj tau tsim txoj kev noj tshuaj tshiab rau cov tshuaj lom neeg tsim kho cov tshuaj lom neeg raws li cov khoom ntawm lub ntiaj teb nto moo Scandinavian tuam txhab. Ob xyoos dhau los, Belmedpreparaty LLC xa thawj cov khoom tshiab rau cov chaw muag tshuaj.

Cov lus teb ntawm cov neeg mob ntshav qab zib tau muaj ob zaug. Ntawm qhov one tes, tau kawg, muaj kev xyiv fab thiab kev cia siab: thaum kawg, "lawv" cov "kev tsim tawm" kev tsim tawm tshuab hluav taws xob tawm.

Rau lub tuam txhab nyiaj hauv lub xeev, qhov no yog qhov kev txuag nyiaj ntau hauv cov nyiaj, thiab rau cov neeg mob ntshav qab zib nws yog qhov lav tias cov insulins niaj hnub (lawv tseem hu ua "tib neeg") tam sim no muaj rau cov menyuam yaus nkaus xwb, tab sis kuj rau cov neeg mob laus, yog li koj tsis tuaj yeem ntshai ntawm cov khoom cuam tshuam thiab yuam kev hloov ntawm ib qho insulin. ntawm lwm qhov (qhov no feem ntau ua rau decompensation ntawm ntshav qab zib).

Tab sis tib lub sijhawm, tib neeg muaj kev ntxhov siab: yuav ua li cas muaj txiaj ntsig zoo thiab siv tau cov tshuaj hauv tsev? Coob leej, ib yam li tus sau ntawm tsab ntawv, tau muab thaj chaw rau lub tswb los ntawm lawv tus kheej kev paub dhau los.

Tawm tsam cov keeb kwm ntawm kev ua tsov rog no, cais cov lus tsis zoo tau sai sai hloov mus ua "snowball" - cov lus xaiv tau loj zuj zus ntawm cov neeg mob ntshav qab zib: "Thiab cov insulins hauv tsev tsis zoo!" Tsis ntev los no, tau muaj kev sib cav thiab tshaj tawm xov xwm hais txog cov ncauj lus no.

Lub caij no, cov kws tshaj lij - cov kws kho mob, cov kws tshawb fawb, cov kws tshaj lij kev tsim khoom - tau ntsiag to, zoo li kev ua lag luam, daws qhov teeb meem.

Cov kev pabcuam endocrinology ntawm cov koom pheej tau tshaj tawm thiab txheeb xyuas txhua qhov tseeb ntawm qhov tsis muaj txiaj ntsig lossis qhov tsis zoo ntawm lub cev tshiab ntawm Belarus insulins, nrog rau muaj cov tshuaj dawb nyob rau hauv lub hwj, uas tsis tau tshem tawm thaum npaj qhov kev daws teebmeem rau kev tswj hwm.

Qhov teeb meem tom kawg yog qhov laj thawj rau kev kho qhov hnyav ntawm insulin manufacturing technology rau hnub no, raws li cov tuam txhab tsim thiab kws kho mob, qhov teeb meem no tau raug daws thaum kawg, tsis muaj "kev sib yuav". Txawm li cas los xij, tus neeg mob yuav tsum ua raws nraim li cov lus qhia rau kev khaws cia thiab siv cov tshuaj kom tau txais cov nyhuv siab tshaj plaws.

Raws li rau cov txheej txheem ntawm kev nqis tes ntawm Belarusian insulin, cov neeg mob lawv tus kheej tau paub zoo: ntawm no ntau nyob ntawm tus neeg qhov yam ntxwv ntawm lub cev, muaj cov mob ntshav qab zib uas "tsis mus" txawm tias cov tshuaj yeeb tshuaj muaj zog tshaj. Yog li no, hauv txoj kev khaws cia muaj cov nyiaj analogues ntawm lwm cov tuam txhab - rau kev xaiv ntawm tus kheej.

Tab sis muaj flip sab rau cov kis.

Txhawm rau cov tshuaj insulin "ua haujlwm" ib puas feem pua, ib tus neeg muaj ntshav qab zib yuav tsum ua qhov yog: ntsuas ntsuas ntshav qab zib, suav cov khoom noj carbohydrates ntau npaum li cas, txiav txim siab noj tshuaj rau insulin txhaj raws qhov xav tau ntawm lub cev. Koj yuav tsum kawm qhov no - los ntawm cov phau ntawv, ntawm "lub tsev kawm mob ntshav qab zib", nrog kev pab ntawm koj tus kws kho mob. Thiab siv cov kev paub tau nce hauv lub neej txhua hnub. Tab sis tsis yog txhua yam, tshwj xeeb tshaj yog cov neeg laus, ua nws.

Natalia Mikhailovna LIKHORAD, tus thawj coj ntawm endocrinology chav ua haujlwm ntawm City Clinical Hospital Tsis Yog 1 hauv Minsk, hais tias: “Thaum peb pom tias cov ntshav qab zib ua rau siv cov insulins Belarusian tshiab, peb ua tib zoo tshawb xyuas qhov xwm txheej nrog txhua tus neeg mob ntawd.

Thiab lawv tau yuav luag ib txwm ntseeg: decompensation yog ua ntej, ntawm lwm cov insulins. Qhov laj thawj yog qhov tsis muaj kev paub txog cov mob ntshav qab zib, kev tsis kam ua rau nws.

Lub luag haujlwm tseem ceeb tau ua los ntawm lub siab lub ntsws ntawm cov neeg mob mus rau qhov kev xav tsis zoo ntawm cov tshuaj insulin tshiab. "

Tsim cov khoom lag luam tshuaj tshiab, mastering nws tso tawm yog qhov nyuaj heev, kim heev thiab ua lag luam ntev. Tsis yog txhua yam hloov tawm tam sim ntawd. Qhov no yuav tsum to taub. Niaj hnub no, endocrinologist ntseeg tias tsis muaj teeb meem nrog qhov zoo ntawm Belarusian insulin. Thiab lawv paub tseeb tias ua tsaug rau cov tshuaj insulins tshiab hauv koom pheej yuav muaj teeb meem tsawg dua nrog kev kho mob ntshav qab zib.

Lub tswv yim ntawm cov kws tshaj lij tau nthuav tawm los ntawm Olga SVERKUNOVA

Protafan: cov lus qhia rau kev siv. Yuav ua li cas stab, dab tsi los hloov

Nruab Nrab Insulin Protafan: Kawm Txhua Yam Koj Xav Tau. Hauv qab no koj yuav pom cov lus qhia rau kev siv sau ua lus yooj yim.

Nkag siab yuav ua li cas xaiv cov tshuaj zoo tshaj plaws rau cov neeg laus thiab cov menyuam yaus mob ntshav qab zib, yuav siv pes tsawg zaus hauv ib hnub los txhaj tshuaj no, dab tsi yog qhov zoo thiab qhov tsis zoo.

Nyeem txog cov kev kho mob zoo uas ua rau koj cov ntshav qab zib 3.9-5.5 mmol / L ruaj khov 24 teev hauv ib hnub, ib yam li cov neeg noj qab haus huv. Tus txheej txheem ntawm Dr. Bernstein, uas tau nyob nrog ntshav qab zib ntau dua 70 xyoo, los pab tiv thaiv kab mob hnyav heev.

Protafan yog ib qho tshuaj nruab nrab uas siv los kho ntau tus neeg mob ntshav qab zib hauv cov teb chaws hais lus Lav Xias. Nws yog tsim los ntawm lub tuam txhab nto moo thoob ntiaj teb Novo Nordisk. Cov tshuaj insulin hauv nruab nrab tseem muaj ntshuam txawv thiab npaj hauv tsev Humulin NPH, Insuman Bazal, Biosulin N, Rinsulin NPH thiab lwm yam. Nplooj ntawv no yuav muaj txiaj ntsig zoo rau cov ntshav qab zib uas tau kho nrog cov tshuaj no.

Nruab Nrab Insulin Protafan: Cov Lus Qhia Ntxiv

Ntau tus neeg mob siab xav txog qhov uas Protafan tuaj yeem hloov nrog. Hauv qab no koj yuav pom cov lus teb rau lo lus nug no. Cov lus qhia tshwj xeeb tshaj yog kev sib piv ntawm nruab nrab-ua yeeb yam insulin thiab tshuaj tshiab, Levemir.

Cov lus qhia rau kev siv

Pharmacological kev txiav txim

Cov tshuaj Insulin txo qis suab thaj, ua rau lub siab thiab cov leeg ntshav kom nqus cov piam thaj ntawm cov ntshav. Tsis tas li, cov tshuaj no stimulates synthesis protein thiab qhov hnyav ntxiv, txwv tsis pub poob phaus. Protafan yog yeeb tshuaj uas qhov kev ua haujlwm ntawm insulin yog qeeb qeeb siv "nruab nrab Hagedorn protamine" protein. Ntawm no, cov protein no tsuas yog hu ua “protamine”. Nws ua rau muaj kev tsis haum tshuaj nyob rau hauv ntau tus neeg mob ntshav qab zib.

Kev ntsuas rau siv

Ntshav Qab Zib 1 hauv cov neeg laus thiab menyuam yaus, nrog rau hom ntshav qab zib hom 2, uas cov ntsiav tshuaj tsis pab ntxiv lawm. Txhawm rau kom koj cov piam thaj kom ruaj, xyuas cov kab lus "Kho Ntshav Qab Zib Hom 1" lossis "Insulin rau Ntshav Qab Zib Hom 2". Kuj pom ntawm no li ntawm seb muaj piam thaj ntshav licas hauv cov ntshav no cov tshuaj hormones pib txhaj.

Thaum txhaj cov tshuaj insulin Protafan, Humulin NPH, Insuman Bazal, Biosulin N lossis Rinsulin NPH, koj yuav tsum ua raws li kev noj zaub mov noj.

Ntshav Qab Zib Hom 2 Ntshav Qab Zib Hom Ntshav Qab Zib Cov Lus Noj Ntawv 9 Lub Limtiam zaub mov: Qauv

Cov Yuav Tsum Tau Ua	Cov ntshav qab zib qis (hypoglycemia). Insulinoma yog qog nqaij hlav uas ua rau tsim cov tshuaj insulin tswj tsis tau. Isofan insulin tsis nkag siab lossis kev tsis haum rau qhov ua haujlwm pab nyob hauv muaj pes tsawg leeg ntawm kev txhaj tshuaj. Tshwj xeeb feem ntau muaj kev tsis haum tshuaj rau cov tshuaj tiv thaiv - cov tsiaj protein uas ua rau lub zog txo qis ntawm cov tshuaj.
Cov lus qhia tshwj xeeb	Nyeem ntawm no vim li cas nws thiaj li xav hloov Protafan insulin nrog Levemir, Tresiba, Lantus lossis Tujeo. Kawm yuav ua li cas xyaw insulin ntshav qab zib nrog cawv. Tshawb xyuas ib tsab xov xwm txog kev ntxhov siab, kev tawm dag zog, kis kab mob, thiab txawm tias huab cua muaj feem cuam tshuam rau cov insulin xav tau ntawm cov ntshav qab zib.
Tsuas tshuaj	Cov sij hawm ntawm kev txhaj tshuaj thiab koob tshuaj yuav tsum tau xaiv tus kheej. Nyeem ntxiv hauv kab lus "Kev suav ntawm cov koob tshuaj nruab nrab thiab ntev ntev rau kev txhaj tshuaj thaum hmo ntuj thiab yav sawv ntxov." Cov kab mob ntshav qab zib uas ua raws li cov zaub mov noj qis yuav tsum txhaj cov tshuaj Protafan insulin qis. Hauv cov koob tshuaj zoo li no, nws yuav tsum raug tswj hwm 3 zaug ib hnub. Kev tswj xyuas ob zaug tsis txaus, thiab ntau heev dua yog, 1 sijhawm ib hnub. Kev txhaj tshuaj rau yav tsaus ntuj tej zaum yuav tsis txaus rau tag nrho hmo ntuj. Protafan raug pom zoo kom hloov los ntawm Levemir, Tresiba, Lantus lossis Tujeo.
Sab sij huam	Feem ntau cov kev mob tshwm sim yog cov ntshav qab zib (ntshav qab zib tsawg). Yog tias cov koob tshuaj insulin muaj ntau heev, txawm tias coma thiab tuag tau tshwm sim. Protafan hauv qhov no tsis muaj phom sij dua luv dua thiab cov chaw npaj ua noj ua haus. Tej zaum yuav muaj lipodystrophy vim qhov ua txhaum ntawm qhov kev pom zoo rau lwm qhov chaw txhaj tshuaj. Kev ua xua muaj qhov ua tau, nrog rau qhov mob hnyav: ua pob liab liab, khaus, tawm pob, kub ib ce, ua tsis taus pa, palpitations, tawm hws, ua tsis taus pa.

Ntau tus neeg mob ntshav qab zib uas kho tau cov tshuaj insulin pom tias nws tsis tuaj yeem ua kom tsis txhob muaj ntshav qab zib hauv lub cev. Qhov tseeb, qhov no tsis yog li ntawd. Koj tuaj yeem khaws cov suab thaj kom ruaj Txawm hais tias muaj mob hnyav autoimmune.

Thiab ntau heev tshaj dua yog li, nrog cov mob hnyav hom 2 mob ntshav qab zib. Tsis tas yuav ua los ntxiv cov ntshav qabzib hauv koj lub cev txhawm rau kom raug tus kheej tiv thaiv ntshav qabzib ntshav qab zib. Saib ib daim vis dis aus uas Dr. Bernstein tham txog qhov teeb meem no.

Cev xeeb tub thiab pub niam mis

Protafan, zoo li lwm hom insulin, yog qhov tsim nyog rau tswj ntshav qab zib thaum cev xeeb tub. Nws tuaj yeem raug pricked li qhia los ntawm kws kho mob. Los ntawm no yuav tsis muaj kev txaus ntshai tseem ceeb rau tus poj niam lossis tus menyuam hauv plab. Sim ua kom tshem tawm cov tshuaj insulin nrog kev noj haus. Nyeem kab lus "Ntshav Qab Zib Cev Rau Mob Ntshav Qab Zib" thiab "Ntshav Qab Zib Zib Zes" rau cov lus qhia ntxiv. Nws yog qhov zoo dua rau cov poj niam cev xeeb tub los hloov Protafan nrog cov kua dej ntev dua, piv txwv li, Levemir.

Kev cuam tshuam nrog lwm yam tshuaj

Kev ua ntawm insulin yog txhim kho los ntawm cov tshuaj ntshav qab zib, MAO inhibitors, ACE inhibitors, carbonic anhydrase inhibitors, bromocriptine, sulfonamides, anabolic steroids, tetracyclines, clofibrate, ketoconazole, mebendazole, pyridoxine, theophylline, cyclophosphamide, cawv, phenyl, phenyl. Nqaij: Cov tshuaj tiv thaiv kev xeeb tub, cov thyroid hormones, thiazide diuretics, heparin, tricyclic antidepressants, sympathomimetics, kev loj hlob hormone, danazole, clonidine, calcium channel blockers, diazoxide, morphine, phenytoin, nicotine. Nyob rau hauv kev cuam tshuam ntawm reserpine thiab salicylates, ob qho tib si ua kom tsis muaj zog thiab nce ntxiv hauv kev ua ntawm cov tshuaj muaj peev xwm ua tau. Tham nrog koj tus kws kho mob!

Noj ntau dhau	Kev mob ntshav khov qis, kev tsis nco qab, ua rau lub hlwb puas, lossis kev tuag yuav tshwm sim. Hauv txoj kev hwm no, insulin Protafan tsis muaj phom sij ntau dua li cov tshuaj yeeb yam luv luv thiab luv luv. Tab sis tseem muaj qhov pheej hmoo. Yog li, kawm txog kev cai saib xyuas kev kub ntxhov rau cov ntshav qog ntshav qab zib, uas yuav tsum tau ua tom tsev thiab hauv tsev kho mob.
Daim ntawv tso tawm	Cov tshuaj muaj nyob rau hauv 3 ml cartridges, zoo li hauv 10 ml fwj. Hauv pob ntawv cardboard - 1 lub raj mis lossis 5 daim cartridges. Cov insulin no tsis pob tshab. Nws zoo li cov kua huab huab uas yuav tsum tau muab co ua ntej ua ntej txhaj tshuaj.
Cov lus thiab cov xwm txheej ntawm kev cia	Txhawm rau kom tsis txhob muaj kev puas tsuaj rau tshuaj, kawm cov cai rau khaws cov tshuaj insulin thiab ua tib zoo ua raws lawv. Lub txee lub neej ntawm kev ncua rau kev tswj hwm subcutaneous ntawm 100 IU / ml yog 30 hli. Lub raj mis qhib lossis lub taub ntim cov taub yuav tsum tau siv li ntawm 6 lub lim tiam.
Muaj pes tsawg leeg	Cov tshuaj ua haujlwm nquag yog tib neeg caj ces engineering insulin isophane. Cov neeg siv zam - zinc chloride, glycerin, metacresol, phenol, sodium hydrogen phosphate dihydrate, protamine sulfate, sodium hydroxide thiab / lossis hydrochloric acid los kho cov pH, dej rau kev txhaj tshuaj.

Ob lub qhov muag (retinopathy) Mob raum (nephropathy) Mob ko taw mob taw: ceg, pob qij txha, taub hau

Hauv qab no yog cov ntaub ntawv ntxiv ntsig txog kev npaj tshuaj insulin nruab nrab.

Tshuaj protafan puas yog ib yam yeeb tshuaj dab tsi?

Protafan yog ib qho insulin nruab nrab. Nws pib kom txo qis ntshav qab zib 60-90 feeb tom qab txhaj tshuaj.

Nws muaj cov cim zoo tshaj plaws ntawm kev nqis tes ua, hauv kev sib piv rau cov tshuaj ntev Levemir, Tresiba, Lantus thiab Tujeo. Cov txiaj ntsig no tau mus txog tom qab 3-5 teev.

Raws li txoj cai, nruab nrab insulin yuav tsum tau siv ua ke nrog cov tshuaj luv luv los yog ultrashort. Nyeem ntxiv hauv kab lus “Cov Hom Tshuaj insulin thiab Cov Cuam Tshuam”.

Yuav muab nws ntaus li cas?

Lub caij nyoog raug ntawm kev txhaj tshuaj yog 12-18 teev. Yog li, Protafan pom zoo kom txhaj tshuaj 2 zaug nyob rau ib hnub. Txawm li cas los xij, cov neeg mob ntshav qab zib uas ua raws li kev noj zaub mov noj qis yuav tsum tau txhaj koob tshuaj insulin 2-8 zaug qis dua li cov qauv.

Hauv cov koob tshuaj zoo li no, Protafan siv tau tsis tshaj 8 teev, thiab nws yuav tsum raug tswj hwm peb zaug ib hnub. Feem ntau yuav, kev txhaj tshuaj rau yav tsaus ntuj yuav tsis txaus rau tag nrho hmo ntuj.

Txhawm rau kom tsis txhob muaj teeb meem qab zib thaum sawv ntxov nyob rau ntawm lub plab khoob, nrog rau txo kev pheej hmoo ntawm kev fab tshuaj, nws yog qhov zoo dua los hloov Protafan nrog ib qho ntawm cov tshuaj Levemir, Tresiba, Lantus lossis Tujeo.

Cov tshuaj Protafan tau muab faib ua 3 hno ib hnub?

Qhov zoo tshaj plaws yog los hloov cov insulin nruab nrab nrog Levemir, Lantus, Tujeo lossis Tresiba.

Xws li, rau qee qhov laj thawj, koj yuav tsum tau siv cov Protafan, Humulin NPH, Insuman Bazal, Biosulin N lossis Rinsulin NPH ntxiv mus txuas ntxiv. Hauv qhov no, nws ua rau pom zoo faib nws rau peb qhov hno ib hnub.

Thawj thawj zaug muab tshuaj thaum sawv ntxov, nrawm lawv sawv los. Qhov txhaj thib ob - thaum noj su, qhov txhaj tshuaj tsawg kawg. Qhov thib peb lub sijhawm - thaum tsaus ntuj ua ntej yuav mus pw, kom txog li sai tau.

Cov teeb meem tseem ceeb tshwm sim nrog ib hmos tshuaj. Vim tias qhov kev txiav txim ntawm cov insulin nruab nrab xaus rau sai dhau, nws tsis txaus rau tag nrho hmo ntuj. Ib qho kev nce siab hauv cov koob tshuaj uas tau muab ua ntej yuav mus pw yuav ua rau tsis muaj ntshav qab zib tsawg.

Kev txhaj tshuaj ntawm cov tshuaj insulin Protafan lossis nws cov tshuaj tiv thaiv kab mob hauv ib qho kev noj tshuaj me me, uas tsis ua rau tsis muaj ntshav ntau lub sijhawm, yuav ua rau muaj suab thaj thaum sawv ntxov ntawm lub plab khoob.

Qhov teeb meem no tsis muaj cov tshuaj zoo, tsuas yog hloov mus rau lwm hom tshuaj insulin.

Puas yog hom tshuaj insulin no ua ntej lossis tom qab noj mov?

Protafan tsis yog tsim rau kev nqus ntawm cov zaub mov. Tsis tas li, nws yuav tsis haum nyob rau hauv cov xwm txheej uas koj xav tau kom nrawm nrawm hauv qab zib. Nws yuav tsum tau muab ntaus, tsis hais noj mov, feem ntau nyob rau txhua hnub thaum tib lub sijhawm. Feem ntau, nyob rau hauv parallel nrog nws, lwm qhov kev npaj luv luv lossis ultrashort insulin yog siv, uas yog muab ua ntej noj mov.

Qhov ntau tshaj yog pub rau noj ib hnub twg yog dab tsi?

Kev tsim nyog, qhov ntau tshaj qhov tso cai txhua hnub ntawm qhov nruab nrab ntawm insulin Protafan tseem tsis tau tsim. Nws raug nquahu kom txhaj ntau li qhov tsim nyog kom cov piam thaj hauv ntshav ntawm cov ntshav qab zib tsis sawv ntau.

Txawm li cas los xij, cov koob tshuaj insulin ntau heev ua rau cov ntshav qabzib nce siab, ntau zaus thiab muaj ntshav ntau los ntshav ntau. Yog li, koj yuav tsum nrhiav qhov kev txiav txim siab zoo tshaj plaws.

Nyeem ntxiv hauv kab lus “Kev Ntsuas Cov Tshuaj insulin: Cov Lus Teb rau Cov Lus Nug Txog Ntshav Qab Zib”.

Protafan lossis Levemir: yam tshuaj insulin zoo dua? Dab tsi yog lawv qhov sib txawv?

Levemir zoo dua li Protafan vim tias nws siv sijhawm ntev dua. Nws kuj tsis muaj cov protein protamine, uas feem ntau ua rau ua xua.

Tab sis Protafan, yog tias tsim nyog, tuaj yeem xyaw nrog dej qab ntsev, uas yog muag hauv khw muag tshuaj. Qhov no tseem ceeb thaum them nyiaj mob ntshav qab zib hauv cov menyuam yaus uas xav tau cov tshuaj insulin tsawg.

Levemir tseem txhaj rau cov menyuam yaus hauv daim ntawv diluted, tab sis cov neeg tsim khoom tsis ua raws li kev pom zoo ntawm qhov no.

Kuv tuaj yeem hloov Protafan nrog dab tsi?

Kev siv tshuaj insulin hauv nruab nrab yog qhov pom zoo kom hloov los ntawm ib qho ntawm cov tshuaj hauv qab no: Levemir, Tresiba (zoo tshaj, tab sis kim dua), Lantus lossis Tujeo.

Tej zaum nws yuav tshwm sim uas koj yuav tau muab Protafan dawb, thiab koj yuav tsum yuav lwm hom tshuaj insulin ntev rau koj cov nyiaj. Txawm li cas los xij, koj tseem yuav tsum hloov cov tshuaj.

Vim hais tias kho ntshav qab zib nrog insulin nruab nrab muaj qhov teeb meem tseem ceeb. Nyeem ntxiv txog lawv ntawm no.

Tshuaj Insulin Protafan: tshuaj xyuas ntshav qab zib

Cov poj niam cev tsis tab seeb prick nws?

Kev siv cov koob thib ob ntawm cov tshuaj insulin Protafan, Humulin NPH, Insuman Bazal, Biosulin N thiab Rinsulin NPH thaum cev xeeb tub thiab pub niam mis yog qhov zoo. Nws tau pom zoo los ntawm Ministry of Health. Txawm li cas los xij, nws zoo dua yog siv ib qho ntawm cov kev xaiv rau ntev (txuas ntxiv) insulin teev saum toj no. Txhawm rau tswj cov ntshav qab zib hauv poj niam cev xeeb tub hauv cov poj niam cev xeeb tub, Levemir feem ntau tau kho.

Protamine-insulin ES - Insulin (tib neeg), qhia rau siv, piav qhia, khoom. Tus neeg sawv cev hypoglycemic, ntev ntev-ua yeeb yam insulin - Protamine-insulin xwm txheej ceev

Cov neeg tsim khoom: RUE Belmedpreparaty Republic of Belarus

PBX Code: A10AC01

Pawg Ua Liaj Ua Teb:
Tshuaj kho mob ntshav qab zib

Daim ntawv tso tawm:
Daim ntaub ntawv kws tshuaj. Ncua rau ntawm kev txhaj tshuaj.

Kev taw qhia rau kev siv:
Qab zib ntshav qab zib.

Cov yam ntxwv ntawm Pharmacological:

Cov Tshuaj Hauv Tshuaj Tom qab kev tswj hwm nyob rau hauv daim tawv nqaij (nkag mus rau cov roj ntsha subcutaneous), Protamine-insulin xwm txheej ceev pib ua haujlwm nyob rau hauv 1.5 teev thiab muaj qhov cuam tshuam zoo tshaj plaws ntawm lub sijhawm 4 thiab 12 teev, lub sijhawm siv tshuaj ntau npaum li 24 teev. Vim tias lub sijhawm ua ncua ntev, Protamine-insulin cov xwm txheej hnyav feem ntau tau kho nyob rau hauv kev sib xyaw ua ke nrog insulin npaj ntawm lub sijhawm luv.

Txoj kev thov thiab muab:

Subcutaneously. Tsis zoo, nyob rau hauv uas hyperglycemia thiab glucosuria tsis tshem tawm los ntawm kev noj haus rau 2-3 hnub, ntawm tus nqi ntawm 0.5-1 U / kg, thiab tom qab ntawd cov koob tshuaj tau kho raws li cov glycemic thiab glucosuric profile.

Qhov ntau zaus ntawm kev tswj hwm yuav tsum muaj qhov sib txawv (feem ntau 3-5 zaug siv thaum xaiv koob), thaum tag nrho cov hmab tau muab faib ua ntau ntu, hauv kev faib ua feem rau lub zog nqi ntawm cov zaub mov noj.

Kev txhaj tshuaj yog nqa tawm 15 feeb ua ntej noj mov.

Daim Ntawv Thov Nta:

Cuam tshuam rau kev muaj peev xwm tsav tsheb thiab tswj cov txheej txheem.

Hauv kev sib txuas nrog lub hom phiaj tseem ceeb ntawm insulin, qhov kev hloov pauv ntawm nws hom lossis nyob ntawm qhov tseem ceeb ntawm lub cev lossis lub hlwb kev ntxhov siab, yuav muaj kev poob qis ntawm kev muaj peev xwm tsav lub tsheb lossis tswj ntau cov txheej txheem, nrog rau koom nrog rau lwm cov dej num tsis zoo uas xav tau tshwj xeeb thiab ceev ntawm kev xav thiab lub cev kev xav.

Phiv los sis:

ES cov tshuaj tiv thaiv kab mob tuaj yeem ua rau lub cev ntog ntshav liab, liab, o thiab khaus khaus tuaj yeem tshwm ntawm thaj chaw txhaj tshuaj (thiaj li hu ua kev fab tshuaj hauv zos). Feem ntau, nrog kev siv tshuaj txuas ntxiv, cov tsos mob no ploj mus li ntawm ob peb lub lis piam.

Thawj thawj zaug pib nrog kev kho mob insulin, nws tuaj yeem cuam tshuam qhov muag tsis pom lossis o ntawm cov ceg.

Qhov kev txhaj tshuaj ntau heev nyob rau tib qho chaw tuaj yeem ua rau daim tawv nqaij lossis cov nqaij mos (cov nqaij mos).

Kev sib cuam tshuam nrog lwm qhov kev lag luam tshuaj:

Muaj ntau tus kws muag tshuaj uas cuam tshuam rau kev xav tau cov tshuaj insulin:

Cov tshuaj tiv thaiv kab mob rau hauv lub cev, monoamine oxidase inhibitors (MAOs), tsis muaj kev xaiv tshuaj beta-blockers, angiotensin hloov enzyme (ACE) inhibitors, salicylates, anabolic steroids thiab glucorticoids, qhov ncauj tiv thaiv kab mob, thiazide diuretics, cov thyroid hormones, thyroid amide cov tshuaj hormones, danoid sympathomimetides

Noj ntau dhau

Cov tsos mob: Thaum tus neeg noj haus ntau dhau hwv lawm, tej zaum yuav muaj kev txhim kho hypoglycemia.

Kev Kho Mob: tus neeg mob tuaj yeem tshem cov ntshav qab zib tsawg los ntawm nws tus kheej, noj qab zib lossis carbohydrate-nplua nuj zaub mov hauv. Yog li, nws pom zoo kom nqa cov piam thaj, qab zib, ncuav qab zib lossis kua txiv qab zib nrog nws txhua lub sijhawm nyob hauv cov ntshav qab zib uas tsis muaj ntshav qab zib.

Hauv cov teeb meem languid, thaum tus neeg mob poob qab nco txog, 40% kua nplaum tov yog tso tshuaj rau cev, mob ntshav khov, subcutaneously, mob ntshav qab zib - glucagon. Tom qab nws rov qab nco qab, tus neeg mob tau qhia kom noj cov khoom noj uas muaj cov khoom noj carbohydrate kom tiv thaiv kev rov qab txhim kho ntshav qab zib.

Cia rau cov neeg mob:

Lub raj mis nrog cov tshuaj tiv thaiv Protamine-Insulin Xwm Ceev, uas koj tab tom siv tam sim no, tuaj yeem muab tso rau hauv chav tsev kub (txog 25 ° C) txog li 6 lub lis piam.

Cov Vials uas tiv thaiv thaum muaj xwm ceev-Insulin thaum muaj xwm ceev yuav tsum tsis txhob raug tshav kub lossis ncaj qha tshav ntuj thiab yuav tsum tsis txhob tso kom khov. Khaws cov tshuaj tiv thaiv Protulin-Insulin Xwmtxheej Ceev rau qhov chaw tsis pub menyuam yaus siv tau.

Tsis txhob siv cov tshuaj insulin tom qab hnub tas sij hawm luam tawm ntawm lub pob. Tsis txhob siv Protamine-Insulin Ceev yog qhov kev daws teeb meem tsis meej, npub lossis yuav luag tsis txaus.

Tso tawm daim ntawv, muaj pes tsawg leeg thiab ntim khoom

Qhov ncua kev txhaj tshuaj yog dawb, thaum sawv ntsug, qhov kev ncua tawm rooj, cov kua saum cov nag lossis daus yog qhov tseeb, tsis muaj xim lossis yuav luag tsis muaj xim, cov nag lossis daus tau yooj yim resuspended nrog maj mam tshee.

1 ml
tib neeg kev tshawb fawb tshuab engineering insulin	100 IU

Cov muaj tswv yim: protamine sulfate, disodium phosphate dihydrate, zinc chloride, phenol, metacresol, glycerol, dej rau thiab.

10 ml - fwj (1) - ntim.

Cov tshuaj insulin nrog cov tshuaj tiv thaiv ua haujlwm li cas?

Cov tshuaj tshwj xeeb hu ua protamine ntxiv rau nruab nrab ntawm insulins kom qeeb qhov nqus ntawm qhov tshuaj los ntawm thaj chaw txhaj tshuaj. Ua tsaug rau cov tshuaj tiv thaiv, qhov pib ntawm kev txo qis hauv cov ntshav qab zib pib ob lossis plaub teev tom qab kev tswj hwm.

Qhov siab tshaj plaws tshwm sim tom qab 4-9 teev, thiab tag nrho lub sijhawm yog los ntawm 10 mus rau 16 teev. Xws li cov kev ntsuas ntawm tus nqi ntawm qhov pib ntawm cov nyhuv hypoglycemic ua rau nws muaj peev xwm ua rau cov insulins hloov pauv cov nyhuv ntawm cov peev txheej zais cia.

Protamine ua rau kev tsim cov tshuaj insulin nyob rau hauv daim ntawv ntawm flakes, yog li ntawd cov tsos ntawm cov tshuaj tiv thaiv insulin yog huab, thiab txhua yam kev npaj ntawm luv luv insulins yog pob tshab. Cov tshuaj muaj pes tsawg leeg kuj suav nrog zinc chloride, sodium phosphate, phenol (khaws cia) thiab glycerin. Ib qho milliliter ntawm kev ncua kev tiv thaiv ntawm cov tshuaj tiv thaiv-zinc-insulin muaj 40 PIECES ntawm lawm.

Kev npaj ua tshuaj insulin uas ua los ntawm RUE Belmedpreparaty muaj cov npe lag luam Protamine-Insulin ChS. Tus mechanism ntawm kev txiav txim ntawm cov tshuaj no yog piav qhia los ntawm cov teebmeem:

Kev sib cuam tshuam nrog lub receptor ntawm lub cell membrane.
Qhov tsim ntawm qhov insulin receptor complex.
Hauv cov roj ntsha ntawm lub siab, cov leeg nqaij thiab cov qog adipose, qhov kev sib txuas ntawm cov enzymes pib.
Cov piam thaj yog nqus thiab nqus los ntawm cov ntaub so ntswg.
Kev tso ntshav qab zib kom ntau dua.
Qhov tsim los ntawm cov rog, protein thiab glycogen yog tsa.
Hauv lub siab, qhov tsim ntawm cov kua nplaum luv luv yuav tsum poob.

Tag nrho cov txheej txheem no yog ua rau txo qis ntawm cov piam thaj hauv cov ntshav thiab siv nws los tsim lub zog hauv lub cell. Qhov pib ntawm tus nqi thiab tag nrho lub sijhawm ua haujlwm ntawm Protamine insulin ES yog nyob ntawm qhov koob tshuaj siv, hom kev thiab qhov chaw txhaj tshuaj.

Hauv tib tus neeg, cov kev ntsuas no yuav txawv rau hnub sib txawv.

Kev qhia rau kev siv thiab ntau npaum li cas ntawm cov tshuaj

Kev npaj tshuaj tiv thaiv-zinc-insulin tau qhia rau cov neeg mob uas muaj thawj hom ntshav qab zib mellitus, thiab tseem tuaj yeem pom zoo rau cov ntshav qabzib nyob hauv hom thib ob.

Qhov no tuaj yeem tiv thaiv cov ntsiav tshuaj kom txo cov ntshav qab zib, ntxiv nrog kev sib kis lossis lwm yam kabmob ntxiv, ntxiv rau thaum cev xeeb tub. Cov neeg mob uas muaj hom 2 mob ntshav qab zib mellitus tseem pauv mus rau kev kho mob insulin yog tias mob ntshav qab zib nrog cov mob hnyav los yog mob ntshav tsis haum.

Cov tshuaj xws li cov tshuaj tiv thaiv-zinc-insulin yog qhia thaum kev phais mob yog tias tsim nyog kuaj ntshav qab zib thiab cov lej glycemic muaj ntau dhau heev lawm lossis yog tias muaj contraindications rau cov ntsiav tshuaj.

ES protamine-insulin yog muab tshuaj subcutaneously, nws qhov ntau npaum li cas yog nyob ntawm tus neeg hyperglycemia thiab suav rau nruab nrab ntawm 1 kg ntawm lub cev qhov hnyav. Kev tswj hwm txhua hnub nyob ntawm 0.5 txog 1 chav tsev.

Cov yam ntxwv ntawm cov tshuaj:

Nws yog muab ib leeg nkaus xwb subcutaneously. Kev tswj hwm ntawm qhov raug tshem tawm ntawm cov tshuaj insulin yog txwv.
Lub raj mis kaw yog cia rau hauv tub yees, thiab thaum siv thaum sov txog 25 degrees txog li 6 lub lis piam.
Khaws cov tshuaj insulin uas siv rau hauv chav sov (txog 25 ° C) rau 6 lub lis piam.
Lub ntsuas kub ntawm insulin nrog qhov kev qhia yuav tsum yog chav sov.
Nyob hauv qab ntawm cua sov, ncaj qha tshav ntuj, khov, tiv thaiv insulin poob nws lub zog.
Ua ntej tswj cov tshuaj protamine, insulin zinc xav kom yob rau hauv xib teg kom txog thaum nws du thiab muaj huab. Yog tias qhov no ua tsis tiav, ces cov tshuaj tsis raug txwv.

Qhov chaw txhaj tshuaj tuaj yeem xaiv nyob ntawm tus neeg mob lub siab nyiam, tab sis nws yuav tsum tau yug los hauv lub siab tias nws tau nqus tusyees thiab maj mam dhau ntawm tus ncej. Qhov thib ob pom zoo qhov chaw yog thaj tsam lub xub pwg (deltoid leeg). Txhua lub sijhawm koj yuav tsum xaiv qhov chaw tshiab nyob hauv tib thaj chaw ua haujlwm kom tsis txhob rhuav tshem cov nqaij mos subcutaneous.

Yog tias tus neeg mob tau txais kev noj qab haus huv ntau ntxiv ntawm kev siv tshuaj insulin, tom qab ntawd kev saib xyuas ntawm cov tshuaj tiv thaiv zinc ua yeeb yam ua rau thaum sawv ntxov lossis yav tsaus ntuj, thiab thaum qhia, ob zaug (sawv ntxov thiab yav tsaus ntuj). Ua ntej yuav noj mov, siv hom tshuaj insulin luv luv.

Hauv hom mob ntshav qab zib hom thib ob, ntau zaus Protamine-insulin ES yog muab nrog kev sib xyaw nrog cov tshuaj glypoglycemic, uas tau sau tseg rau kev tswj hwm qhov ncauj, los txhim kho lawv cov nyhuv.

Teeb meem ntawm Kev Kho Mob Insulin

Feem ntau cov teeb meem ntawm kev siv tshuaj insulin yog ib qho kev txo cov ntshav qabzib hauv qab cov theem ib txwm nyob. Qhov no tau ua kom yooj yim los ntawm kev noj zaub mov tsis zoo nrog qhov muaj cov carbohydrates tsawg thiab qhov siab ntawm insulin, hla zaub mov noj, kev ntxhov siab ntawm lub cev, hloov chaw txhaj tshuaj.

Kev mob ntshav qab zib yog tshwm sim los ntawm cov kab mob sib kis, tshwj xeeb yog cov neeg kub taub hau, zawv plab, ntuav, nrog rau kev sib koom tes ntawm cov tshuaj uas txhim kho kev ua haujlwm ntawm insulin.

Qhov pib sai ntawm cov tsos mob ntawm kev kub siab yog feem ntau rau kev kho mob insulin. Feem ntau, cov neeg mob hnov lub siab ntxhov siab, kiv taub hau, tawm hws txias, txhais tes tshee, tsis muaj zog, txawv txav, mob taub hau thiab palpitations.

Cov tawv nqaij yuav daj ntseg, tshaib plab ntxiv rau tib lub sijhawm thaum xeev siab tshwm sim. Tom qab ntawd txoj kev nco qab yuav ntxhov siab thiab tus neeg mob poob rau hauv coma. Cov suab thaj txo qis hauv cov ntshav qab zib yuav cuam tshuam rau lub hlwb thiab yog tias tsis kho, cov neeg mob yuav muaj kev pheej hmoo tuag.

Yog hais tias tus neeg mob ntshav qab zib tau meej pem, ces koj tuaj yeem daws qhov kev tawm tsam siv cov suab thaj los yog kua txiv qab zib, ncuav qab zib. Nrog lub siab ntawm cov ntshav qib siab hypoglycemia, cov tshuaj muaj qabzib thiab cov kua nplaum glucose yog muab rau tshuaj. Tom qab txhim kho kev noj qab haus huv, tus neeg mob yuav tsum tau noj kom meej meej kom tsis muaj kev tawm tsam ntxiv.

Xaiv cov koob tshuaj tsis haum lossis kev tswj hwm tsis txaus siab tuaj yeem ua rau muaj mob hyperglycemia hauv cov neeg mob tsis txaus. Nws cov tsos mob nce zuj zus, qhov tshwj xeeb tshaj yog cov yam ntxwv tsis pub dhau ob peb teev, qee zaum txog ob hnub. Nqhis nce ntxiv, zis tso zis nce ntxiv, qab los noj mov tsis muaj zog.

Tom qab ntawd muaj xeev ntuav, ntuav, tsis hnov tsw ntawm acetone los ntawm lub qhov ncauj. Thaum tsis muaj cov tshuaj insulin, tus neeg mob poob rau hauv lub dag zog tsis xeev. Yuav tsum tau txais kev saib xyuas xwm txheej ceev rau tus mob ntshav qab zib ua kom tsis nco qab thiab pawg neeg ua haujlwm hauv lub tsheb thauj neeg mob.

Txhawm rau xaiv cov koob tshuaj kom raug, nws yog ib qho tsim nyog yuav tsum tau coj mus rau hauv kev txiav txim siab tias thaum tus neeg mob lub cev lossis cov kab mob hloov pauv, kev kho mob yuav tsum tau ua. Nws pom hauv cov xwm txheej zoo li no:

Kev tsis sib haum ntawm cov thyroid caj pas.
Kab mob rau daim siab lossis lub raum, tshwj xeeb hauv cov laus.
Tus kab mob kis.
Txhawb nqa lub cev ntau dua.
Hloov mus rau lwm yam khoom noj.
Hloov cov hom insulin, cov tsim khoom, cov hloov pauv ntawm tsiaj mus rau tib neeg.

Kev siv cov inulin thiab tshuaj los ntawm pawg thiazolidinediones (Aktos, Avandia) nce kev pheej hmoo ntawm lub plawv tsis ua haujlwm. Yog li, cov neeg mob uas ua tsis tau haujlwm hauv lub siab yog qhia kom tswj lub cev qhov hnyav kom thiaj li kuaj pom qhov ua rau lub cev ploj.

Kev ua xua tuaj yeem ua raws qhov chaw nyob rau hauv daim ntawv ntawm o, liab, lossis khaus ntawm daim tawv nqaij. Lawv feem ntau luv luv nyob thiab dhau ntawm lawv tus kheej. Cov kev tsis haum ntawm tib neeg ua xua ua rau cov tsos mob li no: tawm pob rau ntawm lub cev, xeev siab, angioedema, tachycardia, ua tsis taus pa. Thaum lawv tshwm sim, kev kho tshwj xeeb raug ntsuas.

Kev tiv thaiv thaum muaj xwm ceev-insulin yog qhov txawv txav rau ib tus neeg lub cev tsis muaj zog thiab tsis muaj ntshav qab zib.

Insulin Protamine thaum cev xeeb tub thiab lactation

Txij li thaum cov tshuaj insulin tsis hla cov txiaj ntsig, thaum cev xeeb tub nws tuaj yeem siv los them ntshav qab zib. Thaum npaj kev cev xeeb tub, kev soj ntsuam tag nrho ntawm cov poj niam uas muaj ntshav qab zib tau qhia.

Thawj lub hlis nce txog tom qab ntawm qhov kev txo qis hauv qhov xav tau rau cov tshuaj insulin, thiab qhov thib ob thiab thib peb nrog kev nce qib zuj zus hauv cov tshuaj tsis raug cai. tom qab yug menyuam, kev kho cov tshuaj insulin yog ua tiav li niaj zaus. Thaum lub sijhawm yug menyuam, qhov kev txo qis ntawm cov tshuaj tso cai yuav tshwm sim.

Kev lactation thiab kev tswj tshuaj ntawm cov tshuaj insulin tuaj yeem ua ke, vim tias cov kua dej tsis tuaj yeem nkag mus rau hauv niam mis. Tab sis kev hloov pauv keeb kwm ntawm poj niam xav tau kev ntsuas ntau dua ntawm qib glycemia thiab xaiv cov koob tshuaj uas yog.

Kev cuam tshuam ntawm insulin nrog lwm yam tshuaj

Kev ua ntawm insulin yog txhim kho thaum ua ke nrog cov piam thaj txo cov ntsiav tshuaj, beta-blockers, sulfonamides, tetracycline, lithium npaj, vitamin B6.

Bromocriptine, anabolic steroids. Kev mob ntshav qab zib tsawg tuaj yeem tshwm sim nrog kev sib xyaw ntawm cov tshuaj insulin thiab ketokenazole, clofibrate, mebendazole, cyclophosphamide, nrog rau cov dej cawv ethyl.

Cov neeg mob tau mob siab rau lo lus nug yuav ua li cas txo cov tshuaj insulin hauv cov ntshav. Nicotine, morphine, clonidine, danazole, ntsiav tshuaj tiv thaiv kab mob, heparin, thiazide diuretics, glucocorticosteroids, tricyclic antidepressants, thyroid hormones, sympathomimetics thiab calcium antagonists tuaj yeem txo insulin kev ua si.

Daim vis dis aus hauv tsab xov xwm no qhia txog thaum yuav tsum muaj insulin thiab yuav txhaj li cas.

Kev ntsuas rau siv

yam 1 mob ntshav qab zib mellitus (insulin-dependant),
yam 2 mob ntshav qab zib mellitus (non-insulin-dependant): theem ntawm kev tawm tsam cov tshuaj tiv thaiv kab mob hauv lub qhov ncauj, ib feem tawm tsam cov tshuaj no (thaum kho sib txuam), cov kab mob sib kis, cev xeeb tub.

Kev noj tshuaj ntxiv

Kev tiv thaiv thaum muaj xwm ceev-insulin yog npaj rau SC cov thawj coj. Cov tshuaj tsis tuaj yeem nkag rau hauv / hauv.

Tus kws kho mob txiav txim siab muab cov tshuaj ntawm cov tshuaj ib lub zuj zus rau txhua kis, raws cov theem ntawm cov piam thaj hauv cov ntshav. Qhov nruab nrab, kev siv tshuaj txhua hnub los ntawm 0.5 mus rau 1 IU / kg lub cev qhov hnyav, nyob ntawm tus neeg ntawd tus yam ntxwv ntawm tus neeg mob thiab theem ntawm cov ntshav nyob hauv lub cev.

Qhov kub ntawm cov tshuaj insulin yuav tsum nyob ntawm chav sov. Thaum muaj xwm ceev-tshuaj insulin feem ntau yog tswj subcutaneously hauv tus ncej puab. Thaum s / c nkag mus rau hauv tus ncej puab, cov tshuaj yuav nqus qeeb dua thiab ntau dua tusyees dua li nrog kev hno hauv lwm qhov chaw.

Kev hno tuaj yeem ua tau nyob hauv thaj av ntawm deltoid leeg ntawm lub xub pwg. Ua kev txhaj tshuaj rau hauv cov tawv nqaij txo qhov kev pheej hmoo ntawm kev nkag mus rau hauv cov leeg nqaij. Nws yog ib qho tsim nyog yuav tsum hloov chaw txhaj tshuaj nyob rau hauv thaj chaw anatomical thiaj li tiv thaiv kev txhim kho ntawm lipodystrophy.

Hauv hom 2 mob ntshav qab zib mellitus, Protamine-Insulin Xwm Ceev tuaj yeem siv nrog kev siv tshuaj ntawm qhov ncauj hypoglycemic hauv rooj plaub thaum kev tswj hwm tus kheej ntawm cov tshuaj no tsis them nyiaj rau ntshav qab zib.

Cev xeeb tub thiab lactation

Thaum lub sijhawm thiab yug tom qab yug, insulin yuav tsum poob ntau. Tsis ntev tom qab yug los, xav tau cov tshuaj insulin sai sai rau qib uas yog ua ntej cev xeeb tub.

Tsis muaj kev txwv rau kev kho mob ntshav qab zib mellitus nrog tshuaj insulin thaum pub niam mis, zoo li tshuaj insulin rau leej niam muaj kev nyab xeeb rau tus menyuam. Txawm li cas los xij, nws yuav tsim nyog los txo cov koob tshuaj insulin, yog li ntawd, yuav tsum tau ua tib zoo saib xyuas kom txog thaum qhov xav tau ntawm insulin.

Protamine-insulin xwm ceev, raug muab ncua kev txhaj tshuaj rau 100me / ml - catalog - ruv Belmedpreparaty

PROTAMIN-INSULIN thaum muaj xwm ceev, raug muab ncua kev txhaj tshuaj 100 IU / mlLub Npe Tsis Muaj Npe InternationalCov Insulin (Tib Neeg) .Isulin (Tib Neeg)TxhaisBiosulin N, Gansulin N, Insuman Bazal GT, Insuran NPH, Protafan NMCov tshuaj pab pawg kho mobTus neeg sawv cev hypoglycemic, insulin ntev heevMuaj pes tsawg leeg1 ml ntawm cov tshuaj muaj: cov tshuaj nquag siv yog ua los ntawm tib neeg cov tshuaj insulin - 100MEATX Code: A10AC01.Pharmacological kev txiav tximTom qab kev tswj hwm nyob rau hauv daim tawv nqaij (rau hauv cov nqaij mos subcutaneous) Cov tshuaj tiv thaiv thaum muaj xwm txheej ceev pib ua nyob rau hauv 1.5 teev thiab muaj qhov cuam tshuam ntau tshaj plaws ntawm lub sijhawm 4 thiab 12 teev, cov sijhawm siv tshuaj ntau npaum li 24 teev. Vim tias lub sijhawm ua ntev npaum li cas, tiv thaiv cov tshuaj tiv thaiv kab mob thaum muaj xwm txheej ceev feem ntau tau txuam nrog kev ua yeeb yam luv luv.Kev ntsuas rau sivRau kev kho mob ntshav qab zib.Tsuas tshuaj thiab tswj hwmSubcutaneously. Tus neeg mob hauv tus neeg hyperglycemia thiab glucosuria tsis tau tshem tawm los ntawm kev noj zaub mov noj rau 2-3 hnub, ntawm tus nqi ntawm 0.5-1 U / kg, thiab tom qab ntawd cov koob tshuaj tau kho raws li cov glycemic thiab glucosuric profile. Qhov ntau zaus ntawm kev tswj hwm yuav tsum muaj qhov sib txawv (feem ntau 3-5 zaug siv thaum xaiv ib koob), thaum tag nrho cov hmab tau muab faib ua ntau ntu, hauv kev faib ua feem rau lub zog nqi ntawm cov zaub mov noj. Kev txhaj tshuaj yog nqa tawm 15 feeb ua ntej noj mov.Cov lus qhia tshwj xeebLub raj mis tiv thaiv kev kub ntxhov ntawm Protamine-Insulin Kev kub ntxhov uas koj siv tam sim no tuaj yeem khaws cia rau hauv chav tsev qhov kub (txog 25 ° C) mus txog 6 lub lis piam. Lub teeb thiab yuav tsum tsis txhob ua kom khov. Tsis txhob cia cov tshuaj Protamine-Insulin ES tsis txhob ncav cuag cov menyuam yaus. Tsis txhob siv tshuaj insulin tom qab hnub tas sij hawm luam tawm ntawm lub pob. pob tshab, tsis muaj xim lossis yuav luag tsis muaj xim. Cuam tshuam rau kev muaj peev xwm tsav tsheb thiab tswj cov tswv yim Hauv kev txuas nrog lub hom phiaj tseem ceeb ntawm insulin, hloov nws hom lossis nyob rau ntawm qhov muaj mob lub cev lossis lub siab, nws muaj peev xwm los txo lub peev xwm tsav lub tsheb lossis tswj ntau yam mechanisms, nrog rau lwm yam dej num cov kev ua si muaj feem phom sij uas xav tau kev saib xyuas thiab nrawm ntawm lub hlwb thiab lub cev kev hloov.Sab sij huamProtamine-insulin ES tuaj yeem ua rau mob ntshav qab zib, liab, o thiab khaus tuaj yeem tshwm sim ntawm qhov chaw txhaj tshuaj (qhov thiaj li hu ua kev fab tshuaj hauv zos). Feem ntau, nrog kev siv tshuaj txuas ntxiv, cov tsos mob no ploj mus li ntawm ob peb lub lis piam. Thawj txoj kev kho mob nrog cov tshuaj insulin, yuav cuam tshuam qhov muag tsis pom kev lossis o rau ntawm qhov kawg. Cov kev txhaj tshuaj ntau dhau ntawm tib qho chaw tuaj yeem ua rau daim tawv nqaij lossis subcutaneous nqaij (lipodystrophy).Cov Yuav Tsum Tau UaKev ntshav siab. Txhawb ib tus neeg rhiab rau insulin lossis qee yam ntawm cov tshuaj.Kev cuam tshuam nrog lwm yam tshuajMuaj ntau cov tshuaj uas cuam tshuam rau kev xav tau tshuaj insulin: Cov tshuaj tiv thaiv kab mob hypoglycemic, los ntawm monoamine oxidase inhibitors (MAOs), tsis muaj kev xaiv tshuaj beta-blockers, angiotensin hloov enzyme (ACE) inhibitors, salicylates, anabolic steroids thiab glucorticoids, tshuaj tiv thaiv tsis haum, thyroid diuretics, thyroid diuretics, sympathomimetics, danazol thiab octreotide.Noj ntau dhauCov kev kho mob: tus neeg mob tuaj yeem tshem tawm qhov tsis muaj ntshav qab zib tsawg tsawg los ntawm kev noj cov piam thaj lossis cov khoom noj uas muaj carbohydrate hauv. Yog li, nws raug nquahu kom cov neeg mob ntshav qab zib mellitus yuav tsum nqa cov piam thaj, qab zib, ncuav qab zib los yog kua txiv qab zib nrog lawv. Thaum muaj mob hnyav, thaum tus neeg mob tsis nco qab lawm, 40% cov kua nplaum ua rau cov tshuaj ua kom zoo, intramuscularly, subcutaneously, intravenously - glucagon. Tom qab nws rov qab nco qab, tus neeg mob tau pom zoo kom noj cov khoom noj uas muaj cov khoom noj carbohydrate kom tiv thaiv kev rov qab txhim kho hypoglycemia.Daim ntawv tso tawmNcua rau kev txhaj tshuaj 100 IU / ml hauv 10 ml vials. Cov.Cov Ntaub Ntawv Xov Xwm

txiav txim, insulin, tshuaj

Cov tshuaj tiv thaiv thaum muaj xwm ceev insulin: cov lus qhia rau kev siv thiab tshuaj xyuas - Tawm tsam ntshav qab zib

1 ml ntawm cov tshuaj muaj: cov tshuaj nquag: tib neeg cov tshuaj lom neeg cov tshuaj insulin 100 IU,

Tshuaj tiv thaiv insulinum

Txo cov ntshav qab zib kom tsawg, cov neeg mob ntshav qab zib raug mob ntshav qab zib hom 2 raug nquahu kom noj cov tshuaj tiv thaiv "Protamine-Insulin", uas pab tua glycemia. Cov tshuaj muaj cov cwj pwm nyuaj thiab pab txhawb lub cev thaum lub sijhawm muaj teeb meem hauv cov suab thaj hauv qab thiab nws yuav ua rau kev tiv thaiv ntawm cov teeb meem.

Cov tshuaj no yog dab tsi?

Cov tshuaj tau los ntawm qhov ua kom siv DNA thev naus laus zis thev naus laus zis thiab yog cov ua haujlwm nruab nrab ntawm insulins. Cov tshuaj txhaj dawb dawb yuav muaj qhov nag lossis daus uas yaj yooj yim nrog kev co.

Cov tshuaj no yog tsim nyog rau cov nthuav dav cov neeg tuaj saib ntawm cov neeg mob.

Ua tsaug rau qee yam me me ntawm kev siv yeeb tshuaj, kev kho tshuaj insulin nrog cov tshuaj tiv thaiv kab mob tso cai rau cov menyuam yaus thiab cov neeg laus kom noj qab zib li qub los ntawm kev txhaj tshuaj ntau zaus hauv ib hnub.

Nws ua haujlwm li cas?

Qhov kev txiav txim ntawm cov tshuaj yog ua raws li kev nce ntawm kev thauj mus los rau hauv cov piam thaj hauv qab, vim tias kev txo qis hauv cov ntshav qab zib tau tiav.

"Protamine-insulin" pib ua ib teev lossis ob teev tom qab kev tswj hwm thiab nws cov nyhuv kav ntev txog 10-15 teev. Hauv qee tus neeg mob, qhov kev txiav txim yuav raug muab ncua mus rau ib hnub.

Txij li cov zinc yog ib feem ntawm cov tshuaj lag luam, cov tshuaj hu ua "Protamine-zinc-insulin." 1 ml ntawm kev tov muaj 40 units ntawm cov tshuaj hormones.

Kev taw qhia rau kev siv "Protamine-Insulin"

Cov tshuaj tuaj yeem coj los ntawm cov neeg mob ntshav qab zib ntawm ob hom.

Cov tshuaj yog tshuaj rau hom 1 thiab hom 2 ntshav qab zib. Nws raug nquahu kom noj ua ntej kev phais mob, nrog rau cov neeg mob hauv kev kuaj ntshav qab zib thawj zaug thiab kev xaiv cov tshuaj yog nqa los ntawm kos.

"Insulin Zinc" yog siv txhawm rau txo cov piam thaj thiab tsim nyog rau cov neeg tsis muaj qhov xav tau ceev ntawm qhov tshuaj. Yog tias tsim nyog, txhim kho cov nyhuv ntawm cov insulin luv luv, ob qho tshuaj no raug txhaj raws li cov txheej txheem xaiv hauv chaw kuaj mob.

Yuav thov li cas thiab koob tshuaj?

Cov tshuaj yog muab tshuaj subcutaneously raws li kws kho mob sau tseg. Qhov ntau npaum li cas tau muab suav los suav ib zaug zuj zus thiab tuaj yeem hloov kho thaum kho mob. Qhov ntsuas nruab nrab yog tsau rau ntawm qib 0.5-1.0 units nyob rau ib hnub. Rau cov neeg mob ntshav qab zib nrog lub raum txuas ntxiv thiab mob siab tsis txaus thiab cov neeg laus laus, cov koob tshuaj yog txiav kom tsis txhob muaj teeb meem.

Kev txhaj tshuaj yog pom zoo hauv tus ncej, plab, caj npab, lossis pob tw. Yog tias tsim nyog, txhawm rau ua kom cov nyhuv nrawm dua, xaiv ib qho chaw ntawm lub plab lossis ncej puab. Txhawm rau kom ncua kev ua ntawm cov tshuaj, nws yog pricked hauv forearm. Kev txhaj tshuaj yog ib qho yooj yim los ua koj tus kheej hauv tsev. "Cov tshuaj tiv thaiv" thaum muab tshuaj yuav tsum nyob ntawm chav sov.

Txhawm rau kom cov tshuaj daws kom tau zoo thiab homogeneous, cov ampoule yuav tsum tau co ua ntej nkag mus rau hauv cov kua dej mus rau hauv cov phwj.

"Protamine" tuaj yeem raug txhaj nrog luv luv insulins los txhim kho cov nyhuv thiab ua rau lub luag haujlwm ntev.

Cev Xeeb Tub thiab Kev Kho Mob Siv

Cov tshuaj no muaj kev nyab xeeb rau cov niam hluas.

"Protamine-insulin" muaj kev nyab xeeb rau cov poj niam ua menyuam yaus vim tias nws tsis hla lub tsho me nyuam thiab ua rau leej niam lub cev nkaus xwb.

Lub chav kawm ntawm kev kho mob nrog tshuaj yeeb yog pom zoo kom mob siab rau kev npaj ntawm kev xeeb tub thiab yug menyuam. Hauv thawj peb lub hlis twg, cov koob tshuaj tau raug txo qis, vim muaj ntau cov tshuaj hormones ntau dua.

Tom qab ntawv xav tau cov tshuaj insulin ntau ntxiv.

Thaum lub sijhawm rov ua kom rov zoo thiab rov qab lactation, cov tshuaj tsis muaj kev txwv rau kev nkag mus. Cov koob tshuaj raug kho los ntawm kws kho mob. Cov tshuaj yeeb dej caw tsis ua rau tus me nyuam mos liab raug mob, tab sis kev kho mob niam yog ua tiav los ntawm kev saib xyuas kev kho mob txhawm rau zam kom tsis txhob muaj teeb meem tawg thiab muaj teeb meem. Tom qab ob peb hlis, insulin qib txawm tawm thiab ncav cuag qib kev xeeb tub.

Muaj teeb meem tshwm sim

Cov kev tshawb fawb soj ntsuam paub meej txog kev nyab xeeb ntawm cov tshuaj, cov teeb meem tshwm sim los ntawm kev haus tshuaj thiab ua rau muaj kev tsis haum xeeb ntawm lub cev. Kev phiv cuam tshuam rau cov kab mob ntawm txoj hlab ntsws thiab endocrine.

Cov neeg mob tuaj yeem ua rau lub cev metabolic tsis txaus thiab ua rau lub cev tsis ua haujlwm ntawm lub cev metabolic tsis pom kev, tsis pom kev. Qhov tshwm sim feem ntau yog o tuaj ntawm thaj chaw txhaj tshuaj. Txo kom tsawg rau lawv, nws yog qhov yuav tsum tau hloov chaw txhaj tshuaj ntawm cov tshuaj.

Cov tsos mob hauv qab no kuj tseem tuaj yeem tshwm sim:

Ib qho kev tsis txaus siab tom qab noj cov tshuaj tuaj yeem yog eczema.

tawv nqaij ua pob ua ntxaij, eczema, tev ntawm epidermis,
kev pom ntawm kev ua pa luv, Quincke's edema,
pw ua ke, dhia tsis xwm yeem,
mob taub hau, tshee hnyo, tawv nqaij daj, tshaib plab thiab nqhis dej,
ntshav qog.

Sib piv nrog lwm cov tshuaj

Qee cov tshuaj yuav txhim khu lossis ua kom lub zog tsis zoo ntawm cov tshuaj, ua rau muaj kev noj tshuaj tsis ntau. Kev siv zog yog pom thaum noj "Protamine" nrog lwm tus neeg hypoglycemic, inhibitors thiab beta-blockers.

Ib qho zoo li no tshwm sim tom qab noj cov khoom sib xyaw uas muaj ethanol thiab lithium. Txhawm rau kom tsis txhob txais cov kev tsis zoo, tus neeg mob yuav tsum soj ntsuam cov qib ntawm cov piam thaj tas li.

Yog tias koj xav siv tshuaj uas tsis haum nrog kev pheej hmoo, koj yuav tsum sab laj nrog kws kho mob.

Noj zaub mov ntsim yuav cuam tshuam rau qhov ua tau zoo ntawm cov tshuaj.

Cov nyhuv hauv lub ntsej muag hypoglycemic txo qis nrog kev siv ib txhij nrog kev tiv thaiv kab mob hauv qhov ncauj thiab estrogens, tshuaj diuretic, glucocorticosteroids, nicotine thiab morphines, nrog rau lwm yam tshuaj, cov npe tag nrho ntawm uas tau qhia hauv cov lus qhia rau cov kws tshuaj. Cov zaub mov ntsim thiab cawv tuaj yeem cuam tshuam rau qhov sai thiab ua tau ntawm cov tshuaj. Cov tshuaj tiv thaiv kev txob txob cov zaub mov yog ib leeg.

Analogues ntawm cov tshuaj

Rau kev hloov ib ntus lossis ua tiav cov tshuaj, zoo ib yam li nruab nrab ua haujlwm insulins raug siv, xws li Iletin II NPH, Neosulin NPH, Monodar B.

Kev hloov pauv ntawm cov tshuaj rau kev kho yog nqa tawm maj. Kev sib xyaw nrog ob lossis ntau qhov zoo sib xws hauv cov tshuaj hauv ib zaug yog zam zoo. Tus kws kho mob yuav tsum xaiv los hloov chaw.

Kev hloov pauv tsis raug tso cai los ntawm ib qho tshuaj lag luam mus rau lwm qhov kev pheej hmoo ntawm kev tshwm sim thiab kev ua xua ntawm lub cev.

Cov tshuaj tiv thaiv thaum muaj xwm ceev: cov lus qhia rau kev siv thiab tshuaj xyuas

Kev kho mob ntshav qab zib yog nqa tawm siv cov tshuaj uas, thaum tsis muaj cov khoom tsim ntawm lawv tus kheej hormone (insulin), tuaj yeem txo qis glycemia thiab tiv thaiv kom tsis txhob muaj kab mob ntxiv.

Txhua yam tshuaj tuaj yeem faib ua ob pawg loj: insulins ntawm ntau qhov kev txiav txim siab thiab cov tshuaj siv. Hauv thawj hom mob ntshav qab zib, cov neeg mob xav tau cov tshuaj insulin, kev kho mob ntawm cov neeg mob ntshav qab zib hom 2 koom nrog kev koom ua ke nrog kev kho mob nyob rau hauv muaj cov cim qhia.

Nqa tawm cov tshuaj insulin ua kom rov ua lub suab nrov ntawm kev tsim tawm thiab tso tawm cov tshuaj hormones los ntawm islet hlwb ntawm lub txiav, yog li ntawd, cov tshuaj nrog luv, nruab nrab thiab ntev ua yog xav tau.