Reduxin Met: Tshuaj tshuaj xyuas
Hauv ob txoj kev txhim kho no muaj cov sib xyaw sibutramine, uas yog muab cov txheej txheem ntawm kom poob phaus. Qhov no yog qhov muaj zog anorexigenic tshuaj muaj lub zog zoo nyob rau hauv nruab nrab lub paj hlwb.Cov. Tam sim no, cov tshuaj uas muaj cov khoom siv no tsuas yog muab tshuaj nkaus xwb.
Nws tau raug pov thawj pom tias Reduxin tuaj yeem muaj yees ntxiv, yog li nws qhov kev siv yuav tsum muaj kev kho kom raug.
Reduxin Met yog qhov txuas ntxiv ntawm thawj zaug thiab tau siv rau qhov kev hnyav hnyav hnyav kom zoo rau kev kho mob. Kev siv qee yam ntawm cov tebchaw tsuas yog los ntawm qhov zoo nkauj pom xwb. Kev qhia rau kev siv cov sibutramine-based khoom yog cov rog nrog lub cev nyhav ntawm lub cev thiab cov kab mob hnyav nce hauv cov ntshav qab zib. Txhawm rau kho qhov yooj yim ntawm daim duab, cov tshuaj zoo li no yuav tsis ua haujlwm. Koj yuav tsum nkag siab tias qhov sib txawv ntawm kev tsim cov tshuaj yeeb yaj kiab kom yooj yim rau kev poob phaus thiab lub zog tsim nrog sibutramine yog loj heev.
Kev siv Reduxine yog ua tau tsuas yog tias qhov txiaj ntsig ntawm qhov kev ua ntawm qhov muaj pes tsawg leeg yuav siab dua qhov kev puas tsuaj los ntawm cov neeg rog dhau los. Kev liam tag nrho rau ntau yam kev sib tw, suav nrog:
- kev mob hlwb
- mob ntsws
- kab mob plawv
- laus lawm
- cev xeeb tub thiab lactation,
- mob siab thiab mob raum,
- organic hom rog,
- ntshav siab
- bulimia leeg.
Reduksin yuav tsum siv nrog ceev faj thaum muaj mob cholelithiasis, coagulation tsis meej, arrhythmias, thiab lwm yam teeb meem cuam tshuam. Tus kws kho mob uas tuaj koom tuaj yeem sau tshuaj rau hom tshuaj no tsuas yog tom qab kuaj xyuas tus mob ntawm tus neeg mob thiab qhov xwm txheej zoo ntawm kev kho mob.
Qhia txog ntawm cov tshuaj
Ib qho ntawm cov tshuaj zoo no yog, yog tias koj nyeem cov tshuaj xyuas, Reduxine Met 15 mg. Coob tus neeg ntseeg nws cov tshuaj hu ua Reduxin. Yog li ntawd, txhawm rau kom tsis txhob nkag siab yuam kev, peb yuav xyuas seb qhov txawv nruab nrab ntawm lawv yog dab tsi. “Met” hauv lub npe txhais tau hais tias yog yam tshuaj metformin. Ob qho tshuaj muaj kwv yees tib lub zog ntawm kev nqis tes ua, txawm li cas los xij, Reduxine Met tau khav cov ntawv ntau dua thiab ua tiav.
Nws tus nqi yog siab dua li ib txwm "Reduxin". Raws li cov chaw tsim khoom, Metformin tuaj yeem daws cov teebmeem ntawm kev rog rog los ntawm cov ntshav qab zib mellitus, vim nws ua rau cov neeg txais insulin ntau dua, ua rau cov kua nplaum tawm mus. Ob qho tshuaj muaj qhov zoo sib xws hauv kev siv.
Saib xyuas cov kev cai sau tseg los ntawm kev qhia, nws muaj peev xwm ua kom hnyav thiab nyab xeeb lub cev qhov hnyav. Txawm li cas los xij, ib qho yuav tsum coj mus rau hauv tus account tias cov tshuaj no ntau heev, uas tsis ua rau nws dav.
Cov Nta Tseem Ceeb
Yog li, cov yeeb yam tseem ceeb ntawm ob lub tshuaj yog:
- Ob qho tshuaj muaj cov nyhuv anorexigenic.
- Raws li kev txheeb xyuas, Reduxin Met yog kev txhim kho thiab txhim kho version ntawm Reduxin.
- Ob qhov tshuaj tshem tawm qhov xav tau ntawm cov zaub mov nyob ntawm theem kev siab ntsws.
- Ob qho tib si yog sorbents rau cov hnyuv.
Nosological kev faib tawm (ICD-10)
Txheej cov ntsiav tshuaj thiab tsiav tshuaj | 1 teeb |
ntsiav tshuaj | 1 tab. |
cov tshuaj nquag: | |
metformin hydrochloride | 850 mg |
tus zam: MCC - 25.5 mg, croscarmellose sodium - 51 mg, dej huv - 17 mg, povidone K17 (polyvinylpyrrolidone) - 68 mg, magnesium stearate - 8,5 mg | |
tsiav tshuaj | 1 lub kaus mom. |
yam tshuaj: | |
sibutramine hydrochloride monohydrate | 10/15 mg |
MCC | 158.5 / 153.5 mg |
tus zam: calcium stearate - 1.5 / 1.5 mg | |
tshuaj ntsiav (rau qhov ntau npaum 10 mg): titanium dioxide - 2%, zas azorubine - 0.0041%, xim xiav pob zeb xiav - 0.0441%, nkaws - txog 100% | |
tshuaj ntsiav (rau qhov ntau npaum ntawm 15 mg): titanium dioxide - 2%, xaim xim xiav xiav - 0.2737%, gelatin - txog 100% |
Kev piav qhia ntawm daim ntawv tshuaj
Ntsiav tshuaj oval biconvex dawb lossis yuav luag dawb nrog lub thais ntawm ib sab.
Cov tshuaj ntsiav rau ntau npaum li 10 mg: Zauv 2 yog xiav.
Cov tshuaj ntsiav rau qhov ntau npaum ntawm 15 mg: Naj npawb 2 xiav.
Tus txheem lub ntsiab lus - hmoov ntawm cov xim dawb lossis dawb nrog lub zas daj me ntsis.
Cov Tshuaj Hauv Tshuaj
Cov tshuaj Reduxin ® Met muaj ob qho tshuaj sib txawv hauv ib pob: ib tus neeg sawv cev hypoglycemic rau kev tswj hwm qhov ncauj ntawm pab pawg biguanide ua cov ntsiav tshuaj - metformin thiab tshuaj zoo xws li tshuaj ntsiav rau kev rog rog uas muaj sibutramine thiab MCC.
Kev siv tib lub sijhawm ntawm metformin thiab sibutramine nrog MCC nce kho kom zoo dua ntawm kev sib xyaw ua ke siv nyob rau hauv cov neeg mob rog thiab hom ntshav qab zib hom 2.
Qhov tshuaj tiv thaiv ntshav qab zib hauv qhov ncauj los ntawm pab pawg biguanide txo hyperglycemia yam tsis tau coj mus rau kev txhim kho hypoglycemia. Tsis zoo li sulfonylurea derivatives, nws tsis txhawb kev tiv thaiv insulin secretion thiab tsis ua rau muaj kev cuam tshuam hypoglycemic hauv cov neeg noj qab haus huv. Tsub qhov rhiab heev ntawm peripheral receptors rau insulin thiab kev siv cov kua nplaum los ntawm lub hlwb. Nws inhibits gluconeogenesis nyob rau hauv daim siab. Ncua kev nqus ntawm cov carbohydrates hauv cov hnyuv. Metformin stimulates glycogen synthesis los ntawm kev ua ntawm glycogen synthase. Tsub kom muaj peev xwm thauj tau txhua yam ntawm cov khoom thauj ua kua roj ntau dua. Tsis tas li ntawd, nws muaj txiaj ntsig zoo ntawm lipid metabolism: nws txo cov ntsiab lus ntawm cov roj (cholesterol) tag nrho, LDL thiab triglycerides. Thaum noj cov tshuaj metformin, tus neeg mob lub cev hnyav dua li qub tseem ruaj khov lossis txo qis.
Nws yog cov prodrug thiab exerts nws cov nyhuv. hauv vivo vim muaj cov metabolites (amines thawj thiab theem nrab) uas inhibit reuptake ntawm monoamines (serotonin, norepinephrine thiab dopamine). Kev nce ntxiv hauv cov ntsiab lus ntawm cov neurotransmitters hauv cov lus sib tham tau nce qhov kev ua haujlwm ntawm central 5-HT-serotonin thiab adrenergic receptors, uas ua rau muaj qhov nce ntxiv ntawm qhov txaus siab thiab qhov khoom noj tsawg dua, nrog rau kev nce hauv thermal ntau lawm. Indirectly qhib beta ua3-adrenoreceptors, sibutramine ua rau ntawm daim ntaub adipose xim av. Qhov kev poob qis hauv lub cev qhov hnyav yog nrog los ntawm kev nce siab ntawm HDL hauv cov ntshav dej thiab cov tshuaj triglycerides txo qis, tag nrho cov cholesterol, LDL thiab uric acid. Sibutramine thiab nws cov metabolites tsis cuam tshuam rau kev tso tawm ntawm monoamines, tsis inhibit MAO, tsis muaj kev sib raug zoo rau ntau ntawm cov neurotransmitter receptors, suav nrog serotonin (5-HT1-, 5-NT1A-, 5-HT1B-, 5-NT2C-), adrenergic (beta1-, beta2-, beta3-, Alpha1-, Alpha2-), dopamine (D1-, D2-), muscarinic, histamine (H1-), benzodiazepine thiab glutamate NMDA receptors.
Nws yog ib qho enterosorbent, muaj kev ua kom lub siab ntev thiab muaj cov txiaj ntsig tsis huv uas tsis paub meej. Nws khi thiab tshem tawm ntau cov kab mob me me, cov khoom lag luam ntawm lawv cov kev ua haujlwm tseem ceeb, co toxins ntawm exogenous thiab endogenous xwm, kev ua xua, xenobiotics, thiab ntxiv rau qee yam dhau ntawm qee yam khoom hauv metabolic thiab metabolites lub luag haujlwm rau kev loj hlob ntawm endogenous toxicosis.
Cov Tshuaj Pharmacokinetics
Xuas. Tom qab noj cov tshuaj hauv, metformin yog qhov nkag mus rau hauv lub plab zom mov. Nrog kev sib xyaw ua ke, kev nqus ntawm metformin yog txo thiab qeeb. Kev tsis raug cai ntawm bioavailability yog 50-60%. Cmax hauv cov ntshav yog kwv yees li 2 μg / ml lossis 15 μmol thiab ua tiav tom qab 2.5 teev
Kev xa Khoom. Metformin tau faib sai sai rau hauv cov ntaub so ntswg hauv lub cev. Nws xyaum tsis khi rau cov plasma protein.
Kev zom zaub mov. Nws yog me ntsis metabolized.
Chaw Sau Ntawv. Nws yog tawm los ntawm lub raum. Kev tshem tawm ntawm metformin hauv cov tib neeg muaj kev noj qab haus huv yog 400 ml / min (4 zaug ntau dua li Cl creatinine), uas qhia tau hais tias muaj tubular zais cia. T1/2 kwv yees li 6,5 teev
Chaw Kho Mob Tshwj Xeeb
Hauv cov neeg mob raum tsis ua hauj lwm T1/2 nce, muaj kev pheej hmoo ntawm kev txuam nrog metformin hauv lub cev.
Xuas. Tom qab kev tswj hwm ntawm qhov ncauj, nws nrawm los ntawm lub plab zom mov tsawg kawg 77%. Thaum lub sijhawm pib nkag los ntawm lub siab, nws tau hla biotransformation nyob rau hauv cov cawv ntawm CYP3A4 isoenzyme nrog kev tsim ntawm ob lub cev ua haujlwm (monodesmethylsibutramine (M1) thiab didesmethylsibutramine (M2). Tom qab noj ib koob tshuaj 15 mg Cmax Ml yog 4 ng / ml (3.2–8.8 ng / ml), M2 yog 6.4 ng / ml (5.6–7.2 ng / ml). Cmax ua tiav tom qab 1.2 teev (sibutramine), 3-4 teev (nquag metabolites). Concurrent Noj Lub Zog Cmax metabolites los ntawm 30% thiab nce Tmax rau 3 teev yam tsis pauv ntawm AUC.
Kev xa Khoom. Nws yog sai faib rau ntawm ntaub. Kev sib txuas lus nrog cov protein yog 97 (sibutramine) thiab 94% (Ml thiab M2). Css nquag metabolites nyob rau hauv cov ntshav tau mus txog hauv 4 hnub tom qab pib kho thiab kwv yees li 2 lub sij hawm nyob rau hauv cov ntshav ntshav tom qab noj ib koob.
Kev ntsuas phoo thiab nthuav tawm. Lub cev siv roj ntsha ua rau lub cev tsis ua haujlwm nrog rau lub cev thiab ua kom lub cev tsis muaj zog, uas tsuas yog tawm los ntawm lub raum. T1/2 sibutramine - 1.1 teev, Ml - 14 teev, M2 - 16 teev.
Chaw Kho Mob Tshwj Xeeb
Paul Tam sim no muaj tsawg cov ntaub ntawv tsis tau qhia tias muaj kev kuaj mob sib txawv hauv pharmacokinetics hauv cov txiv neej thiab poj niam
Laus lub caij nyoog. Pharmacokinetics hauv cov neeg laus noj qab haus huv (hnub nyoog nruab nrab 70 xyoo) zoo ib yam li cov hluas.
Tsis hlauv. Cov teeb meem tsis ua hauj lwm tsis muaj kev cuam tshuam rau AUC ntawm cov tshuaj metabolites Ml thiab M2, tshwj tsis yog rau metabolite M2 hauv cov neeg mob thaum kawg mob raum tsis ua haujlwm raws lim ntshav.
Daim siab ua haujlwm. Hauv cov neeg mob uas muaj lub siab tsis ua hauj lwm zoo tom qab siv ib zaug sibutramine, AUC ntawm lub cev nquag metabolites Ml thiab M2 yog 24% siab dua hauv cov neeg muaj kev noj qab haus huv.
Cov Lus Qhia Reduxin ® Met
Txo qhov hnyav lub cev hauv qab no:
Kev rog rog Alimentary nrog BMI ntawm 27 kg / m 2 lossis ntau dua ua ke nrog hom 2 ntshav qab zib thiab dyslipidemia.
Kev rog rog Alimentary nrog BMI ntau dua 30 kg / m 2 hauv cov neeg mob uas muaj ntshav qab zib thiab lwm yam kev pheej hmoo rau kev tsim hom 2 mob ntshav qab zib mellitus, uas kev hloov pauv hauv lub neej tsis tau tso cai rau kev tswj glycemic txaus.
Cov Yuav Tsum Tau Ua
muaj lub cev tsis haum rau lub tshuaj,
ketoacidosis, mob ntshav qab zib precoma, mob ntshav qab zib coma,
lub raum khiav tsis zoo (Cl creatinine tsawg dua 45 ml / min),
lub siab ua tsis taus haujlwm,
muaj mob hnyav uas muaj qhov pheej hmoo ntawm lub raum ua tsis tiav: lub cev qhuav dej (nrog rau mob raws plab, ntuav), cov kab mob kis hnyav, ua rau poob siab,
cov kab mob plawv (keeb kwm thiab tam sim no): kev mob plawv rau lub plawv (myocardial infarction, angina pectoris), kab mob ntsig txog ntshav ntawm lub cev, tachycardia, arrhythmia, kab mob cerebrovascular (mob hlab ntsha tawg, mob hlab ntsha mus ib ntus), mob plawv tsis ua hauj lwm hauv theem ntawm decompensation
tsis tuaj yeem saib xyuas cov ntshav liab (ntshav siab dua 145/90 hli Hg - saib "Cov Lus Qhia Tshwj Xeeb"),
kev soj ntsuam cov kab mob ntawm cov mob huam thiab mob ntev tuaj yeem ua rau kev txhim kho cov nqaij mos hypoxia (suav nrog kev ua pa tsis ua haujlwm, mob plawv tsis ua hauj lwm, mob plawv tsis txaus nrog hemodynamics tsis khov, mob myocardial infarction),
kev haus dej cawv ntev, mob hnyav ethanol,
benign prostatic hyperplasia,
kev phais mob siab thiab mob nyhav (thaum insulin kho yog qhia),
lactic acidosis (nrog rau keeb kwm ntawm)
teeb tsa pharmacological los yog quav tshuaj yeeb tshuaj,
ib lub sijhawm tsawg dua 48 teev ua ntej thiab nyob hauv 48 teev tom qab ua kev tshawb fawb radioisotope lossis X-ray nrog kev qhia ntawm iodine-muaj qhov sib piv nruab nrab,
ua raws li kev noj zaub mov kom tsis txhob muaj calories ntau tsawg (tsawg dua 1000 kcal / hnub),
muaj cov organic ua rau kev rog (piv txwv li hypothyroidism),
cov teeb meem noj loj heev - anorexia nervosa lossis bulimia nervosa,
Gilles de la Tourette syndrome (cov ntsiab lus hais dav dav),
concomitant siv MAO inhibitors (suav nrog phentermine, fenfluramine, dexfenfluramine, ethylamfetamine, ephedrine) lossis lawv siv rau 2 lub lis piam ua ntej noj sibutramine thiab 2 lub lis piam tom qab noj nws, lwm yam tshuaj uas ua rau lub hauv nruab nrab cov hlab ntsha uas cuam tshuam rau serotonin reuptake ( xws li tshuaj tiv thaiv kev ntxhov siab), tshuaj tiv thaiv kab mob, pw tsaug zog tshuaj uas muaj cov tryptophan, zoo li lwm cov tshuaj ua kom lub cev txo qis qhov hnyav lossis kho kev mob hlwb,
lactation lub sijhawm
hnub nyoog txog 18 xyoo thiab tshaj 65 xyoo.
Nrog saib xyuas: mob ntshav ncig tsis ua haujlwm, cov kab mob ntawm cov hlab ntsha txhaws (nrog rau keeb kwm ntawm), tshwj tsis yog lub plawv mob ntshav (myocardial infarction, angina pectoris), glaucoma, tshwj xeeb rau lub kaum ntse ntse-txhaws qhov muag, cholelithiasis, mob ntshav siab (tswj hwm thiab keeb kwm), mob hlwb, suav nrog qeeb puas siab puas ntsws kev loj hlob thiab qaug dab peg (suav nrog keeb kwm), qaug dab peg, lub raum lub raum tsis ua haujlwm, me me rau lub raum tsis ua haujlwm (Cl creatinine 45–59 ml / min), keeb kwm ntawm lub cev thiab lub ncauj, lub siab nyiam cr laxation, los ntshav tsis zoo, noj tshuaj uas cuam tshuam rau hemostasis lossis platelet muaj nuj nqi, cov neeg mob hnub nyoog laus dua 60 xyoo, ua haujlwm hnyav lub cev, uas cuam tshuam nrog kev pheej hmoo ntawm kev tsim mob lactic acidosis.
Cev xeeb tub thiab lactation
Txij li tam sim no tsis muaj pov thawj txaus ntawm cov kev tshawb fawb txog kev nyab xeeb ntawm kev cuam tshuam ntawm sibutramine ntawm tus me nyuam, cov tshuaj no yog contraindicated thaum cev xeeb tub.
Cov poj niam nrog tshwj tseg kev muaj me nyuam lub zog thaum noj Reduxin ® Met yuav tsum siv kev tswj kom tsis muaj menyuam.
Kev siv Reduxin ® Met thaum lub sijhawm pub mis niam yog contraindicated.
Sab sij huam
Kev txiav txim siab qhov tseeb ntawm cov kev mob tshwm sim: feem ntau heev (≥1 / 10), feem ntau (≥1 / 100, CNS: feem ntau muaj kev tsis txaus siab saj.
Los ntawm lub plab zom mov: feem ntau - xeev siab, ntuav, raws plab, mob plab, tsis qab los noj mov (feem ntau cov tsos mob no tshwm sim nyob rau hauv thawj zaug ntawm kev kho mob thiab feem ntau kis tau tus kheej), muaj tsawg kawg - kev ua txhaum ntawm lub siab ua haujlwm ntsuas, kab mob siab, tom qab tshem tawm ntawm metformin cov kev tsis txaus ntseeg kiag li ploj mus. Kev noj tshuaj qeeb yuav ua rau lub plab zom mov tsis tuaj yeem.
Ntawm feem ntawm daim tawv nqaij: tsis tshua muaj tshwm sim - kev hloov tawv nqaij xws li erythema, mob pruritus, tawm pob.
Feem ntau, cov kev mob tshwm sim thaum pib kho mob (hauv thawj 4 lub lis piam). Lawv qhov mob hnyav thiab zaus ua haujlwm tsis muaj zog thaum sijhawm. Cov kev mob tshwm sim feem ntau me me thiab thim rov qab.
Los ntawm sab hauv lub hauv nruab nrab ntawm cov hlab hlwb: ntau zaus - lub qhov ncauj qhuav thiab pw tsis tsaug zog, mob taub hau, kiv taub hau, ntxhov siab, mob caj dab, thiab kuj tseem muaj kev hloov pauv hauv lub saj yog feem ntau sau tseg.
Los ntawm CCC: feem ntau - tachycardia, palpitations, vasodilation, nce ntshav siab (nce ntshav siab thaum so los ntawm 1-3 hli Hg thiab nce hauv nruab nrab lub plawv dhia los ntawm 3-7 yeej / min). Hauv qee kis, qhov nce siab tshaj tawm ntshav siab thiab nce siab hauv lub plawv tsis suav nrog. Clinically kev hloov pauv siab hauv ntshav siab thiab cov mem tes tau sau tseg feem ntau thaum pib kho mob (hauv thawj 4-8 lub lis piam). Kev siv Reduxin ® ntsib hauv cov neeg mob ntshav siab - saib "Cov Kev Tshawb Nrhiav Kab Mob" thiab "Cov Lus Qhia Tshwj Xeeb."
Los ntawm lub plab zom mov: heev ntau - tsis qab los noj mov thiab cem quav, feem ntau xeev siab thiab exacerbation ntawm hemorrhoids.Nrog rau qhov nyiam ua kom tawv ncauj thaum ntxov, tswj kev khiav haujlwm ntawm txoj hnyuv yog tsim nyog. Yog tias cem quav tshwm sim, tsum tsis txhob noj thiab noj tshuaj laxative.
Ntawm feem ntawm daim tawv nqaij: feem ntau - tawm hws.
Nyob rau qee qhov teeb meem, cov kev tsis txaus ntseeg hauv qab no tau piav qhia thaum kho nrog sibutramine: dysmenorrhea, edema, zoo li mob khaub thuas, khaus ntawm daim tawv nqaij, mob nraub qaum, mob plab, nce ntxiv hauv kev qab los noj mov, nqhis dej, rhinitis, kev nyuaj siab, qaug zog, lub zog ua haujlwm, ntxhov siab, chim siab, tshee, mob interstitial mob nephritis, los ntshav, Shenlein-Genoch purpura (mob ntshav hauv daim tawv nqaij), ua kom mob, mob thuv ntshav, ua kom muaj ntshav ntau dua ntxiv hauv cov ntshav ua rau cov ntshav enzymes hauv ntshav.
Hauv kev tshaj tawm txog kev lag luam ntawm sibutramine, muaj cov kev tsis zoo ntxiv tau piav qhia, cov npe hauv qab los ntawm cov kab ke hauv nruab nrog cev.
Los ntawm CCC: atrial fibrillation.
Kev tsis haum tshuaj: kev tsis haum lub cev (los ntawm kev tawm pob nyob rau hauv daim tawv nqaij thiab urticaria rau angioedema (Quincke's edema) thiab anaphylaxis).
Los ntawm sab hauv lub hauv nruab nrab ntawm cov hlab hlwb: kev mob hlwb, cov xeev kev xav tua tus kheej, tua tus kheej thiab mania, lub cim xeeb tsis tshua raug ncua, kev tawm tsam. Yog tias muaj cov xwm txheej zoo li no, cov tshuaj yuav tsum tau tsum txuas mus ntxiv.
Ntawm qhov txhia chaw: qhov muag plooj (daim ntaub thaiv ua ntej lub qhov muag).
Los ntawm lub plab zom mov: raws plab, ntuav.
Ntawm feem ntawm daim tawv nqaij: alopecia.
Los ntawm cov kab mob urinary: kev tso zis cia.
Los ntawm kev muaj me nyuam: ejaculation / orgasm cuam tshuam, impotence, coj khaub tsis xwm, poj niam los ntshav.
Kev sib txuam
Cov tshuaj tiv thaiv radiopaque muaj cov Iodine. Tawm tsam keeb kwm yav dhau los ntawm lub raum ua haujlwm tsis zoo hauv cov neeg mob ntshav qab zib mellitus, kev tshawb nrhiav radiological siv iodine-muaj radiopaque cov neeg sawv cev tuaj yeem ua rau kev loj hlob ntawm cov kab mob lactic acidosis. Kev kho mob Metformin yuav tsum tau tshem tawm nyob ntawm kev ua haujlwm ntawm lub raum 48 teev ua ntej lossis thaum lub sijhawm kuaj X-ray siv cov tshuaj iodine-muaj radiopaque thiab tsis rov pib dua ntxov dua 48 teev tom qab, muab tau tias thaum lub sijhawm kuaj lub raum ua haujlwm tau pom zoo li qub.
Cawv Hauv cov cawv ua rau qaug cawv, qhov kev pheej hmoo ntawm kev tsim muaj cov kab mob lactic acidosis nce ntxiv, tshwj xeeb tshaj yog thaum muaj kev noj zaub mov tsis zoo, kev noj zaub mov kom tsawg thiab ua kom lub siab ua haujlwm tsis zoo. Thaum noj cov tshuaj, haus dej cawv thiab tshuaj uas muaj ethanol yuav tsum zam.
Tej kev sib txuam uas xav tau ceev faj
Danazole Kev siv tib lub sijhawm sib xyaw ntawm danazol tsis pom zoo nyob rau hauv kev txiav txim kom tsis txhob muaj cov nyhuv hyperglycemic ntawm tom kawg. Yog tias kev kho mob nrog danazol yog qhov tsim nyog thiab tom qab txiav tawm qhov kawg, kev kho tshuaj metformin yog yuav tsum ua raws li kev tswj xyuas ntshav qabzib.
Chlorpromazine. Thaum noj nyob rau hauv cov koob tshuaj loj (100 mg ib hnub twg) nce qhov kev mloog zoo ntawm cov piam thaj hauv cov ntshav, txo cov tshuaj insulin tawm. Hauv kev kho tshuaj tiv thaiv kev tiv thaiv thiab tom qab siv ceev xwmphem kawg, kev hloov kho koob tshuaj yuav tsum muaj kev tswj hwm ntawm cov ntshav qabzib concentration.
GKS cov txheej txheem thiab hauv ib cheeb tsam txo cov piam thaj hauv kev siab, nce qhov kev mloog ntawm cov piam thaj hauv cov ntshav, qee zaum ua rau ketosis. Hauv kev kho mob ntawm corticosteroids thiab tom qab siv ceev xwmphem qhov ua kom haum rau tom kawg, kev hloov kho tshuaj ntawm metformin yog nyob rau hauv kev tswj hwm ntawm cov ntshav qabzib concentration.
Kev tshuaj ntsuabCov. Kev siv tib lub sijhawm lub voj diuretics tuaj yeem ua rau txoj kev txhim kho ntawm cov kab mob lactic acidosis vim muaj kev ua haujlwm tsis zoo rau lub raum. Metformin yuav tsum tsis txhob raug tshuaj yog tias creatinine Cl qis dua 60 ml / min.
Txhaj Tshuaj Beta2-adrenomimetics. Ua kom cov ntshav qabzib ntau dua vim yog beta ua kom lub zog2-adrenoreceptors. Hauv qhov no, tswj kev saib xyuas ntawm cov concentration ntawm cov piam thaj hauv cov ntshav yog tsim nyog. Yog tias tsim nyog, insulin raug pom zoo.
Nrog rau kev siv cov tshuaj txuas ntxiv saum toj no, yuav tsum tau soj ntsuam ntau dua ntawm cov ntshav qabzib hauv lub ntsej muag, tshwj xeeb yog thaum pib kho. Yog tias tsim nyog, cov koob tshuaj metformin tuaj yeem hloov kho thaum kho thiab tom qab nws txiav.
ACE inhibitors thiab lwm cov tshuaj tiv thaiv kabmob. Yuav txo cov ntshav piam thaj. Yog tias tsim nyog, cov koob tshuaj metformin yuav tsum tau hloov kho.
Nrog rau kev siv thooj txhij ntawm metformin nrog sulfonylurea derivatives, insulin, Acarbose, salicylates ntshav qog ntshav yuav pib mob.
Nifedipine. Nce ntxiv kev nqus thiab Cmax metformin.
Cov tshuaj Cationic (amiloride, digoxin, morphine, procainamide, quinidine, quinine, ranitidine, triamteren, trimethoprim thiab vancomycin), muab zais hauv cov hlaus plab hlaws, sib tw nrog metformin rau cov tubular thauj khoom thiab tej zaum yuav ua rau muaj kev nce ntxiv hauv nws Cmax .
Cov tshuaj tiv thaiv ntawm microsomal oxidation, suav nrog inhibitors ntawm CYP3A4 isoenzyme (suav nrog ketoconazole, erythromycin, cyclosporine). Lub plasma cov ntsiab lus ntawm sibutramine metabolites tau nce nrog qhov nce ntawm lub plawv dhia thiab qhov kev tsis txaus siab hauv kev kho mob hauv QT ntu nruab nrab.
Rifampicin, tshuaj tua kab mob macrolide, phenytoin, carbamazepine, phenobarbital thiab dexamethasone. Tej zaum yuav leeb sibutramine metabolism.
Ib txhij siv ob peb cov tshuaj uas ua rau muaj serotonin hauv ntshav ntshav, tuaj yeem coj mus rau kev tsim tawm ntawm kev cuam tshuam loj. Tsis tshua muaj, nrog kev siv sibutramine tib si nrog SSRIs (tshuaj rau kev kho kev nyuaj siab), qee cov tshuaj siv rau kev kho mob ntawm migraine (sumatriptan, dihydroergotamine), muaj zog analgesics (pentazocine, pethidine, fentanyl) los yog cov tshuaj tiv thaiv kev tiv thaiv (dextromethorphan) tuaj yeem txhim kho cov tshuaj sib ntxiv. cov leeg serotonin.
Sibutramine tsis cuam tshuam qhov txiav txim tshuaj tiv thaiv qhov ncauj.
Cawv Nrog rau kev tswj hwm tib lub sibutramine thiab haus dej cawv, tsis muaj ib qho nce ntawm cov txiaj ntsig tsis zoo ntawm kev haus cawv. Txawm li cas los xij, kev haus dej cawv tsis tau ua ke nrog cov kev pom zoo noj zaub mov zoo thaum noj sibutramine.
Nrog rau kev siv thooj txhij nrog sibutramine lwm cov tshuaj uas cuam tshuam rau hemostasis lossis platelet muaj nuj nqiKev phom sij ntawm los ntshav ntau ntxiv.
Tshuaj sib cuam tshuam nrog kev siv sibutramine tib lub sij hawm nrog tshuaj uas ua rau ntshav nce siab thiab lub plawv dhia, tam sim no tsis to taub tag nrho. Pawg tshuaj no suav nrog cov tshuaj phom ntsig, tshuaj tiv thaiv, mob khaub thuas thiab tshuaj tiv thaiv kev ua xua, uas suav nrog ephedrine lossis pseudoephedrine. Yog li, thaum muaj kev sib txig nrog cov thawj coj ntawm cov tshuaj no nrog sibutramine, kev ceeb toom yuav tsum tau siv.
Kev siv sib xyaw sib xyaw nrog tshuaj kom txo tau qhov hnyav hauv lub cev, ua yeeb yam ntawm lub hauv nruab nrab hauv lub paj hlwb, lossis tshuaj pab hlwb mob hlwb contraindicated.
Txoj kev ntawm daim ntawv thov
Kev rog rog Alimentary nrog lub cev qhov ua cim ntawm ntau dua 28 yog qhov qhia txog qhov tsis tau zoo rau kev noj Reduxine Met. Qhov no yog qhov tseeb tshwj xeeb yog tias kev rog dhau los nrog cov ntshav qab zib thiab dyslipidemia (cuam tshuam cov rog metabolism).
Ib pob ntawm cov tshuaj muaj ob hom tshuaj. Thawj qhov tshuaj ntawm cov tshuaj yuav tsum yog ib qho tshuaj ntsiav ntawm metformin thiab ib qho tshuaj ntsiav ntawm sibutramine. Ntsiav tshuaj yuav tsum noj tib lub sijhawm thaum sawv ntxov thaum noj tshais. Siv Reduxine Met (kev tshuaj xyuas cov kws tshaj lij nco peb txog qhov no), nws yog qhov tseem ceeb rau kev tswj cov ntshav qab zib kom qis. Yog hais tias cov piam thaj qhov tseem ceeb tom qab ob peb lub lis piam ntawm kev tswj hwm tau mus txog qhov zoo tshaj qhov tseem ceeb, ces ntau npaum ntawm cov tshuaj metformin tuaj yeem muab tau ob npaug.
Qhov ib txwm noj ib hnub ntawm metformin yog 1700 mg, tab sis yuav tsum tsis pub tshaj 2550 mg. Txhawm rau tsis ua rau muaj kev phiv, Metformin tau muab faib rau thaum sawv ntxov thiab yav tsaus ntuj.
Yog tias nyob rau thawj lub hlis qhov hnyav tsis tau poob ntau dua ob kilos, ces kev siv tshuaj sibutramine txhua hnub yog nce rau 15 mg. Thov kev thov, kev txiav txim los ntawm kev txheeb xyuas, Reduxine Met rau ntau dua plaub lub hlis tsis pom zoo rau cov neeg uas poob qis. Koj yuav tsum tsis txhob rov ua dua qhov kev kawm yog tias, tom qab tsis kam rau yeeb tshuaj, qhov kev poob ceeb thawj rov qab sai. Cov tshuaj yuav tsum tau ua ke nrog kev noj zaub mov zoo thiab kev ua kom lub cev.
Sab sij huam
Metformin tuaj yeem ua rau cov kev mob tshwm sim hauv qab no:
- Los ntawm lub plab zom mov: tsis qab los noj mov, xeev siab, ntuav, raws plab, pais plab. Qhov tsos mob no zoo li thaum pib txoj kev kho thiab ploj mus nrog kev nce tshuaj.
- Los ntawm ib sab ntawm cov metabolism: lactic acidosis, txo qis dua theem ntawm cov vitamin B12.
- Los ntawm daim siab: mob siab thiab daim siab ua haujlwm tsis tshua muaj.
- Kev ua xua rau: khaus, tawm pob, erythema. Qhov no tau lees paub los ntawm "Reduxin Met" cov lus tshuaj xyuas ntawm kws kho mob.
Sibutramine tuaj yeem ua rau cov kev mob hauv qab no:
- Los ntawm cov hlab plawv system: tawg, lub plawv palpitations.
- Los ntawm lub hauv nruab nrab hauv lub paj hlwb: insomnia, mob taub hau, qhov ncauj qhuav, hloov pauv hauv saj.
- Los ntawm cov hnyuv sab: xeev siab, tsis qab los noj mov, cem quav, exacerbation ntawm hemorrhoids.
Txais tos nrog ceev faj
Ceev faj yuav tsum tau ua, yog tias koj nyeem cov kev txheeb xyuas, Reduxine Met (15 mg) hauv cov xwm txheej hauv qab no:
- Arrhythmia.
- Cov ntshav ncig tsis txaus.
- Mob caj pas
- Tawg siab
- Tshuaj qaug dab peg
- Lub cev muaj zog thiab hais lus tics.
- Tsis hlauv.
- Muaj hnub nyoog tshaj 55 xyoos.
- Neurological ntshawv siab.
Kev txheeb xyuas ntawm kev poob phaus
Reduxin Met (15 mg) yog tsim los ntawm cov tuam txhab Lavxias teb sab OZON. Cov tshuaj nquag ua haujlwm ntawm cov tshuaj yog sibutramine, uas tuaj yeem muas tau nyob rau hauv daim ntawv ntawm Aderan, Meredia, Lintax thiab Kub Kab. Tag nrho cov tshuaj uas raug teev tseg raug tso cai nyob hauv tebchaws Lavxias, qhov ntawd yog, lawv raug nyab xeeb. Qhov no tsis tuaj yeem khav tau ntawm cov khoom noj hauv Suav.
Sibutramine dulls qhov zoo nkaus li kev tshaib kev nqhis thiab tib lub sij hawm ua rau kev xav zoo nkaus. Nws ua rau ntawm cov leeg poob siab thiab tuaj yeem sib ntxiv, yog li, tsis tas yuav tshuaj nws tsis raug tso tawm hauv cov chaw muag tshuaj. Hmoov tsis zoo, hnub no koj tuaj yeem yuav nws hauv khw muag khoom online lossis hauv khw muag tshuaj yam tsis muaj daim ntawv yuav tshuaj. Cov poj niam uas tau sim tshuaj lawm nco ntsoov tias nws ua haujlwm tiag tiag, tab sis koj yuav tsum tsis lees noj zaub mov kiag li. Nws yog qhov tseem ceeb ntau dua rau kev ua kom muaj kev noj qab haus huv thiab muaj kev noj qab haus huv.
Cov kws kho mob tshuaj xyuas
Raws li cov kws tshaj lij, cov tshuaj no tuaj yeem pab txo qhov hnyav.
- Raws li kev txheeb xyuas, Reduxin Met (yees duab saum toj no) pab txo qis ntawm cov zaub mov, uas txhais tau tias cov neeg siv calories ntau yog kwv yees li ob thiab ib nrab, peb zaug.
- Sibutramine tsis muaj yees thiab yog ib txwm muaj lub cev tiv thaiv.
- Yuav luag ib puas feem pua ntawm cov neeg mob tau txo qis qhov qab los noj mov.
- Cov nyhuv ntawm kev noj Rebuksin Met yog qhov ruaj khov.
- Nws yooj yim dua rau cov neeg mob noj cov tshuaj los hloov mus rau cov khoom noj kom tsim nyog.
Txhua qhov saum toj no ua rau nws tuaj yeem txo qhov hnyav, muab qhov kev txhawb zog ntxiv rau kom poob ceeb thawj. Qhov kev tshuaj xyuas ntawm cov neeg uas coj Reduxin Met thiab cov txiaj ntsig ntawm kev tshawb nrhiav ywj siab pom tias 95 feem pua ntawm cov neeg mob, qab los noj mov tsawg dua, thiab nyob rau 5 feem pua ntxiv, qhov rhiab heev ntawm cov zaub mov txais yuav tsawg dua, uas yog txo qhov muaj siab los noj koj cov zaub mov uas koj nyiam.
Rau thawj lub hlis ntawm kev noj tshuaj Reduxine Met (15 mg), txiav txim los ntawm kev txheeb xyuas cov neeg uas poob phaus, cov neeg uas muaj BMI ntawm 26 txog 31 tswj kom poob mus txog xya phaus, ntawm 31 txog 39 lawv tuaj yeem txo lawv qhov hnyav los ntawm yim phaus. Qhov no yog qhov txiaj ntsig zoo, thiab tseem ceeb tshaj - tsis yog qhov ntse, tab sis maj mam tshwm sim.
Ntawm qhov tshwm sim ntawm kev noj tshuaj nyob rau thawj peb lub lis piam, 10 feem pua tau nqhis dej, 12 feem pua yws ntawm lub qhov ncauj qhuav. 11 feem pua ntawm cov neeg mob ua rau cem quav nyob rau qee theem ntawm kev txais neeg mob.Tsuas yog 4 feem pua ntawm cov neeg mob tau ntsib kiv taub hau, xeev siab, khaus, thiab hloov pauv raws li cov nyiam nyiam. 7 feem pua qhia tau teeb meem nrog cov hlab plawv lub cev ua rau mob taub hau, mob plawv, thiab mob ntawm lub cev. 2 feem pua ntawm cov ntsiab lus raug kev txom nyem los ntawm insomnia, txob taus, thiab kev nyuaj siab. Qhov no tau lees paub los ntawm kev txheeb xyuas ntawm Reduxine Met (10 mg).
Nws yog categorically tsis pom zoo los ntawm cov kws tshwj xeeb kom siv cov tshuaj los kho cov duab. Cov tshuaj no tau tsim rau cov neeg muaj rog rog ntawm ntau yam etiologies thiab mob hnyav. Kev siv tsis tau zoo siv nws tuaj yeem zam tsis txhob ua rau muaj kev phom sij rau lub cev tag nrho. Tsuas yog qhov cuam tshuam loj thiab tseem ceeb hauv qhov hnyav los ntawm cov txheej txheem yog cov cim qhia rau noj Reduxine Met. Thiab ntxiv nrog rau cov txiaj ntsig zoo nyob rau hauv daim ntawv ntawm qhov kev poob phaus, stagnation hauv kev txo cov roj hauv lub cev kuj tseem tuaj yeem pom, thaum tom qab kawm tag txoj kev hnyav, nws tseem zoo li nws tau ua thaum pib.
Tsis txhob hnov qab txog tus kheej lub zog ntawm txhua tus kab mob thiab muaj kev ntsuam xyuas zoo txaus qhov xav tau los txuas tshuaj rau txoj kev ua kom poob ceeb thawj.
Dab tsi yog qhov sib txawv ntawm Reduxin Met thiab cov ua ntej dhau los
Txoj kev loj hlob tshiab yog txoj kev sib koom ua ke uas muaj ob yam tshuaj:
- tsiav tshuaj nrog sibutramine - pab txhawb rau kev rog, tiv thaiv kev qab los noj mov, pab txhawb kev noj zaub mov,
- ntsiav tshuaj nrog metformin - cov piam thaj txo qis los ntawm chav kawm biguanide. Nws muaj cov rog ua cov rog.
Cov rog rog tau pom tias muaj txiaj ntsig zoo tshaj plaws rau kev kho mob ntshav qab zib. Metformin pab txhim kho cov insulin receptor rhiab heev thiab pab txhawb nqa kom muaj suab thaj. Qhov tshuaj txhua hnub thaum pib kho yog 1 lub tshuaj metformin thiab 1 tshuaj ntsiav ntawm sibutramine. Lawv tau noj tib lub sijhawm, sib txuas nrog kev haus tshuaj nrog kev noj zaub mov. Yog tias tsis muaj tshwm sim li 2 lub lis piam, kev noj tshuaj ntawm metformin ntau npaum li ob npaug.
Kev siv tshuaj nrog ob qho tshuaj yuav tsis tuaj yeem lees paub yam tsis muaj kev saib xyuas mob. Nyob rau tib lub sijhawm ua kev noj tshuaj, ua ib qho kev noj haus ib leeg thiab ua si lub cev, ua si aerobic ntau, nws yog kws kho.
Thaum muaj ib qho dhau hwv lawm, kev tsis txaus siab ntawm cov hlab ntsha hlwb feem ntau tau pom, uas yog: pw tsis tsaug zog, ntxhov siab, mob taub hau, kiv taub hau.
Qhov sib txawv hauv tus nqi yog tseem tam sim no. Nrog rau kev sib xyaw ua ke ntawm sibutramine, qhov tshiab ntawm Reduxine yuav kim dua.
Dab tsi yog qhov sib txawv ntawm cov tshuaj rau qhov poob phaus reduxin meth thiab reduxin: cov lus piav qhia, cim thiab kev kuaj xyuas
Reduxin Met hauv ib pob muaj ob qho tshuaj sib txawv: ib qho tshuaj hypoglycemic rau kev siv qhov ncauj ntawm pab pawg biguanide, thiab cov tshuaj rau kev kho mob rog nyob rau hauv daim ntawv ntawm tshuaj ntsiav, uas muaj microcrystalline cellulose, nrog rau sibutramine.
Los ntawm thiab loj, ob qho tshuaj no tsim cov nyhuv zoo ib yam hauv lub cev, thiab txawv hauv muaj pes tsawg leeg, uas nyob hauv cov tshuaj "Reduxin Met", tau ua ntau dua. Ntxiv mus, vim qhov tseeb Reduxin Met, hloov kho dua tshiab ntawm cov khoom txheem, nws tus nqi yuav kim me ntsis.
Tsis tas li ntawd, raws li cov tuam txhab tshuaj uas ua lub luag haujlwm tsim kom muaj kev txhim kho ntawm Reduxine, nws yog qhov yuav tsum tau hais txog qhov tseeb tias thaj chaw ntxiv ntawm nws daim ntawv thov yog kev kho mob rog uas tau sawv tawm tsam keeb kwm ntawm ntshav qab zib. Qhov no tau piav qhia los ntawm qhov tseeb tias metformin, uas yog ib feem ntawm cov tshuaj no, txhim kho qhov rhiab ntawm insulin receptors, ua kom cov ntshav qabzib tawm.
Vim tias txhua yam ntawm cov saum toj no, nws yuav tsum raug sau tseg tias ob qho tshuaj yeeb yuav luag zoo tib yam hauv kev siv. Ntxiv mus, Reduxin Met yog kev txhim kho hloov kho dua ntawm Reduxin yooj yim.
Cov yam ntxwv sib txawv ntawm cov tshuaj "Reduxin" thiab nws cov kev mob tshwm sim
Vim tias qhov tseeb hais tias ob yam tshuaj no muaj cov sib xyaw sibutramine, uas muaj cov txiaj ntsig zoo ntawm cov txheej txheem poob phaus, cov tshuaj Reduxin, nrog rau nws cov tshuaj sib xyaw nrog, Reduxin Met, tuaj yeem hu tau cov tshuaj anorexigenic haibCov. Xws li, lawv tuaj yeem raug hu vim tias lawv muaj lub zog zoo rau lub hauv nruab nrab lub paj hlwb. Lwm cov khoom uas ua rau ob lub tshuaj zoo ib yam tseem tuaj yeem yog tias lawv tau faib los ntawm cov tshuaj nkaus xwb. Lub xeev ntawm kev ua haujlwm tau piav qhia los ntawm qhov tseeb hais tias ob yam tshuaj no muaj yees thiab yog vim li cas nws txoj kev siv, yam tsis poob, yuav tsum muaj qee yam kev kuaj mob.
Lub sijhawm ntawm Reduxin tshuaj tau paub rau lub sijhawm ntev dua thiab tam sim no, cov cuab yeej no tuaj yeem suav tias yog tus qauv, thiab tsis yog qee qhov txuas ntxiv, uas yog cov cuab yeej Reduxin Met. Raws li nws cov yam ntxwv sib txawv, contraindications tuaj yeem nkag siab, uas nyob rau hauv cov ntaub ntawv ntawm cov tshuaj no, muaj tag nrho cov npe.
Dab tsi yog qhov sib txawv ntawm Reduxin thiab Reduxin Met?
Raws li peb twb hais rau koj lawm, Reduxin Met yog tshuaj uas cuam tshuam nrog qee yam advanced kev loj hlobCov. Nov yog kev sib txuam tshuaj uas muaj ob qho tshuaj:
- Cov tshuaj ntsiav, uas suav nrog sibutramine. Lawv muaj txiaj ntsig pab txhawb txoj kev rog, tiv thaiv tib neeg kev qab los noj mov thiab cawm ib tug neeg los ntawm kev noj zaub mov noj.
- Metformin ntsiav tshuaj, uas ua raws li kev tshwj xeeb hypoglycemic. Ntawm lwm yam, lawv muaj lub sijhawm los khav ntawm lub xub ntiag ntawm lub cev rog zoo ua.
Qhov tseeb, ob hom tshuaj no muaj qhov zoo tib yam hauv kev sib raug zoo nrog tib neeg lub cev, tab sis lawv tsuas tuaj yeem sib txawv ntawm ib leeg lawv muaj pes tsawg leeg, uas nyob rau hauv rooj plaub ntawm Reduxine Met, tuaj yeem hu tau ua ntau ntau dhau los. Ntxiv mus, vim qhov tseeb tias Reduxin Met yog kev txhim kho ntawm cov qauv tshuaj, nws raug nqi me ntsis.
Ntxiv mus, raws li cov lus tshaj tawm ntawm cov tuam txhab kws kho mob lub luag haujlwm rau kev tsim cov txhim kho ntawm Reduxine, nws yuav tsum raug sau tseg tias kev kho kev rog, uas tau sawv tawm tsam keeb kwm yav dhau los ntawm cov ntshav qab zib yav dhau los, tuaj yeem suav tias yog thaj tsam ntxiv ntawm nws txoj kev siv. Qhov no yog vim qhov tseeb tias metformin, uas yog tam sim no nyob rau hauv qhov muaj pes tsawg leeg ntawm cov tshuaj no, muaj peev xwm txhim kho qhov rhiab ntawm tib neeg receptors rau insulin, yog li ua kom nrawm nrawm rau kev siv cov piam thaj nws tus kheej.
Hauv kev pom ntawm lub ntsiab lus dhau los, nws yuav tsum raug sau tseg tias ob hom tshuaj yeeb tshuaj no yuav luag zoo ib yam ntawm lawv txoj kev siv ncaj qha. Nyob rau tib lub sijhawm, Reduxin Met yog kev hloov kho dua tshiab ntawm Reduxin li ib txwm thiab vim li ntawd vim li cas ntawm thawj cov tshuaj saum toj sau tus nqi me ntsis ntxiv!
Cov yam ntxwv ntawm Reduxin
Reduxin yog ib cov tshuaj uas nws qhov kev ua yog tsom rau kev txo lub cev qhov hnyav thiab muab lub cev rog. Cov khoom xyaw tseem ceeb yog sibutramine (sibutramine hydrochloride monohydrate). Nws rhuav tshem kev tshaib kev nqhis los ntawm kev ua ntawm lub hauv nruab nrab hauv lub paj hlwb.
Reduxin tseem muaj microcrystalline cellulose. Nws kuj tuaj yeem raug ntaus nqi rau cov tshuaj yeeb dej caw. Cellulose yog ib qho zoo heev sorbent. Nws nqus cov co toxins thiab co toxins, uas tom qab ntawd tawm hauv lub cev. Microcrystalline cellulose nyhav o lub plab, nce nws qhov ntim ntau zaus, uas ntxiv rau kev xav zoo nkaus.
Reduxin yog tsim nyob rau hauv daim ntawv ntawm tsiav tshuaj nrog tus nqi ntawm cov tshuaj nquag ntawm sibutramine 10 thiab 15 mg. Cov tshuaj ntsiav tau ntim rau hauv cov hlwv thiab cov thawv ntawv thawv.Tsuas yog kws kho mob yuav tsum tau sau cov tshuaj. Cov tshuaj no tuaj yeem siv los kho cov rog rog nrog rau qhov nce hauv qhov ua rau lub cev ntau dua rau 27 qhab nia. Qee lub sij hawm nws yog tshuaj rau cov neeg mob uas muaj BMI qis dua, yog tias kev rog rog nrog kev loj hlob ntawm ntshav qab zib.
Cov kws tshaj lij pom zoo kom pib siv cov tshuaj no tsuas yog tias ua ntej muaj qhov ua tsis tau tiav txo qhov hnyav los ntawm kev kho kom haum rau kev noj haus lossis siv cov khoom noj kom yuag, nrog rau cov tshuaj muaj zog tsawg dua. Thaum tom qab ib hlis twg ntawm kev noj zaub mov noj haus nrog kev noj haus, nws muaj peev xwm ua kom poob phaus tsawg dua 5%, koj yuav tsum tau sab laj rau tus kws kho mob tshwj xeeb los txiav txim siab txog kev noj tshuaj Reduxine.
Nws yog qhov zoo dua los pib noj 1 tshuaj ntsiav ntawm 10 mg ntawm sibutramine ib hnub. Tom qab ib hlis ntawm kev siv, koj yuav tsum sab laj nrog tus kws kho mob txhawm rau soj ntsuam kev ua haujlwm ntawm kev kho mob. Lub caij nyoog kawg ntawm kev pub nkag yog 1 xyoos. Hauv thawj lub lis piam ntawm kev kho mob, qhov tshwm sim ntawm cov kev mob tshwm sim xws li:
- xeev siab
- kiv taub hau
- qhov ncauj qhuav
- nce hws.
Cov tsos mob tsis zoo no yuav tsum tsis txhob ntxhov siab yog tias lawv mob me. Yog tias muaj cov tsos mob hnyav tshwm sim, nws zoo dua rau sab laj nrog kws kho mob.
Reduxin tuaj yeem siv los kho cov kev rog nrog kev nce ntxiv ntawm lub cev nyhav rau 27 ntu.
Piv ntawm Reduxin Met thiab Reduxin
Reduxin Met thiab Reduxin feem ntau piv. Cov cuab yeej no muaj ntau qhov sib xws, tab sis muaj cov sib txawv tseem ceeb, yog li cov kws tshaj lij tsis xav txog lawv hloov chaw.
Lub ntsiab zoo sib xws ntawm cov tshuaj yog muaj sibutramine thiab microcrystalline cellulose hauv lawv yog cov tshuaj tseem ceeb. Hauv ob qho tib si, koj tuaj yeem xaiv cov tshuaj hauv cov khw muag tshuaj nrog kev noj tshuaj 10 ml thiab 15 mg ntawm sibutramine.
Ob yam tshuaj no yog tshuaj noj thiab tsis tuaj yeem siv tsis tau tus kws kho mob txoj kev pom zoo. Lawv tuaj yeem yuav nrog cov tshuaj kws kho mob. Cov tshuaj yog tsim los kho kev rog kev rog. Lawv tsis raug kho yog tias qhov ntsuas lub cev ua haujlwm yog qis dua 27 units. Cov kws tshaj lij ntseeg tias kev siv cov tshuaj no zoo rau kev noj haus yog tias kev nrhiav zaub mov kom zoo thiab kev siv tshuaj noj kom tsis haum lub cev.
Daim ntawv ntawm kev tso tawm ntawm cov nyiaj muaj cov nyiaj zoo sib xws. Sibutramine yog muag hauv tshuaj ntsiav. Cov neeg tsim kev lag luam cov tshuaj yog tib yam. Ob qho tshuaj yeeb tshuaj yog qhov ua yeeb yam vim tias lawv cuam tshuam rau hauv lub xeev ntawm lub paj hlwb. Lawv tsis ua rau muaj kev quav yeeb tshuaj, tab sis nrog kev siv ntau dhau, cov txiaj ntsig rov qab yog qhov ua tau, uas ua rau lub cev nce ntxiv.
Kev siv cov tshuaj Reduxin Met
Thawj qhov tshuaj ntawm cov tshuaj yog pom zoo nyob rau hauv qhov nyiaj ntawm ib cov tshuaj ntsiav, uas muaj 860 mg ntawm metformin thiab ib ntsiav tshuaj ntawm 10 mg ntawm sibutramine. Ob qho tshuaj yuav tsum tau noj thaum sawv ntxov nyob rau tib lub sijhawm, haus dej ntau nrog rau zaub mov noj.
Nws yog ib qho tsim nyog yuav tau soj ntsuam kev hloov pauv ntawm cov piam thaj hauv cov ntshav thiab txog kev poob phaus. Yog tias tom qab ob peb lub lis piam koj tsis tau ua tiav qhov ntsuas pom ntawm cov piam thaj hauv ntshav, koj yuav tsum nce metformin rau 2 tsiav tshuaj.
Tus qauv txhawb nqa koob tshuaj ntawm metformin 1800 mg rau ib hnubCov. Qhov koob tshuaj ntau tshaj txhua hnub yog 2500 mg. Txo cov kev mob tshwm sim los ntawm lub plab, qhov tshuaj txhua hnub ntawm metformin tau muab faib ua 2 koob tshuaj. Piv txwv li, ib lub cev teev ntuj thaum yav tsaus ntuj.
Yog tias nyob rau hauv ib hlis txij thaum pib mus txog thaum kawg tsis muaj qhov hnyav tshaj 3 kg, ces cov sibutramine nce mus txog 15 mg / hnub.
kev siv Reduxin Met yuav tsum tsis pub ntau tshaj 4 lub hlis hauv cov neeg uas ua tsis zoo rau qhov kev kawm no, uas yog, leej twg thaum lub sijhawm no tsis ua tiav qhov kev poob phaus ntawm 5% ntawm tag nrho.
Qhov kev kho mob tsis tas yuav tsum tau txuas ntxiv thaum, nrog kev kho tom qab tom qab qhov hnyav tau nce mus txog, tus neeg dua nce ntau dua 4 kg hauv qhov hnyav. Lub sijhawm kho yuav tsum tsis pub ntau tshaj 12 hlis.
Kev siv Reduxin Met yuav tsum tshwm sim ib txhij nrog kev noj haus thiab kev tawm dag zog hauv kev saib xyuas ntawm ib tus kws tshaj lij.
Sab sij huam
Phiv los ntawm Metformin:
- Lub plab zom mov: feem ntau ntau - ntuav, tsis qab los, xeev siab, mob plab, raws plab. Feem ntau, cov tsos mob no tshwm sim nyob rau theem pib ntawm kev kho thiab feem ntau dhau nthawv. Maj mam nce lub koob tshuaj kho mob kho txoj hnyuv kom zoo.
- Kev tiv thaiv kab mob: qee zaum - cov kab mob lactic acidosis, nrog rau siv sijhawm ntev, txo qis hauv vitamin B12.
- Mob siab: tsis tshua muaj - kab mob siab thiab mob siab, tom qab siv cov metformin tiav, cov ntaub ntawv no ploj tag.
- Daim tawv nqaij: tsis tshua muaj - pob liab, khaus, erythema.
Sibutramine
Raws li txoj cai, cov kev mob tshwm sim thaum pib ntawm qhov pib, thiab yog, feem ntau, mob me.
- Mob hlab plawv: feem ntau muaj qhov zoo nkaus li ntawm palpitations, tachycardia, vasadilation, nce siab.
- CNS: qhov ncauj qhuav thiab pw ntxhov, mob taub hau, txob taus, saj hloov.
- Daim tawv nqaij ua ke: kev hws siab yog feem ntau pom. Tsis tshua pom muaj - edema, dysmenorrhea, khaus, mob hauv plab thiab sab nraud, mob rhinitis.
- Digestive plab hnyuv siab raum: tsis qab los noj mov, exacerbation ntawm hemorrhoids, xeev siab, cem quav. Thaum cem quav tshwm sim, chav kawm tiav thiab kev siv laxative.
Reduxine Met sib cuam tshuam nrog lwm yam tshuaj li cas?
Metforminum:
- Cawv dej cawv: nrog kev haus cawv ntau dhau, muaj kev pheej hmoo ntawm cov kab mob lactic acidosis nce ntxiv, tshwj xeeb yog cov zaub mov tsis zoo, kev noj zaub mov,
- Iodine-muaj cov kab xoo hluav taws xob sib piv: hauv cov neeg mob ntshav qab zib, mob lactic acidosis yuav tshwm sim.
Kev sib xyaw ua ke uas xav tau ceev faj:
- Chlorpromazine: thaum noj nyob rau hauv cov koob tshuaj tseem ceeb (150 mg rau ib hnub) ntau dua qhov cov piam thaj, txo cov tshuaj insulin. Thaum kho nrog cov tshuaj tiv thaiv kev kho mob thiab tom qab lawv ua tiav, kev kho qhov tshuaj ntawm cov tshuaj nyob ntawm cov ntshav qab zib yog qhov tsim nyog.
- Danazol: nws yog qhov tsis xav kom siv cov danazol tib lub sij hawm txhawm rau txhawm rau txhawm rau tiv thaiv teebmeem hyperglycemic. Yog tias koj xav tau chav kawm ntawm danazol thiab tom qab ua tiav nws, koj yuav tsum kho qhov kev txhaj tshuaj ntawm cov tshuaj metformin uas txheeb ze rau cov piam thaj hauv lub cev.
- Diuretics: kev siv hluav taws xob tib lub sijhawm "voj" diuretins ua rau lub ntsej muag ntawm cov kab mob lactic acidosis vim qhov yuav muaj qhov tsis zoo ntawm lub raum. Tsis txhob siv cov metformin thaum CC tsawg dua 50 ml / min.
- Glucocorticosteroids txo qis qabzib kam rau siab, nce cov piam thaj hauv lub cev, feem ntau tsim ketosis. Thaum kho corticosteroids thiab tom qab ua tiav nws qhov kawg, kev hloov kho tshuaj metformin yuav raug txheeb ze rau cov piam thaj hauv lub cev.
Thaum lub sijhawm siv cov kev qhia saum toj no ib txhij, koj yuav tsum xav tau nquag tswj cov piam thaj hauv lub cev, tshwj xeeb tshaj yog thaum pib mus txog thaum kawg. Yog tias tsim nyog, cov koob tshuaj metformin tuaj yeem hloov kho thaum lub sijhawm kawm thiab tom qab ua tiav.
Kev txhaj tshuaj ntawm cov tshuaj beta-adrenergic agonists ua rau cov piam thaj ntau ntxiv vim qhov tshwm sim los ntawm kev ua kom muaj cov beta-adrenergic receptors. Hauv qhov no, koj yuav tsum tswj hwm cov ntshav qabzib. Hauv qhov no, kev siv cov tshuaj insulin yog qhov tsim nyog.
Thaum tib lub sijhawm siv cov metformin nrog sulfonyl urea, axarbose, insulin, thiab salicylates, qhov tshwm sim ntawm hypoglycemia yog qhov yuav tshwm sim. Nifedipine tsub kom ntau ntxiv kev nqus ntawm metformin.
Angiotensin hloov mus rau enzyme inhibitors thiab lwm yam tshuaj tiv thaiv antihypertensive txo cov piam thaj hauv lub cev.
Reduxin Met: tshuaj xyuas cov kws kho mob
Reduxin Met tsim nyob rau hauv Russia los ntawm OZONCov. Cov tshuaj tseem ceeb ntawm cov tshuaj no yog Sibutramine. Sibutramine kuj tseem tuaj yeem tau yuav hauv cov lag luam nram qab no: Kub Lain, Aderan, Lintax, Meredia.
Tag nrho cov nyiaj no tau pom zoo siv rau hauv peb thaj chaw, thiab raws li, lawv tau nyab xeeb tias lawv tau siv tas. Dab tsi tsis tuaj yeem hais txog cov tshuaj noj haus hauv Suav, piv txwv li, Li Da thiab Zhuidemen ntsiav tshuaj.
Lawv tseem muaj Sibutramine, tab sis hauv ntau qhov txaus ntshai rau tib neeg thiab feem ntau ua ke nrog lwm cov khoom muaj zog.
Sibutramine zoo heev ua rau kev muaj siab ntawm tag nrho, txo qhov qab los noj mov. Qhov tshwm sim no tau ua tiav los ntawm kev nqis tes ua ntawm cov hlab ntsha, yog li no cov tshuaj no tau tshwj tseg los ntawm kws kho mob.
Hauv tebchaws Russia, txhua yam tshuaj uas muaj sibutramine nyob rau hauv cov npe tshuaj uas tsuas yog muaj nyob hauv tshuaj. Alas, txiav txim los ntawm kev tshuaj xyuas, niaj hnub no hauv qee lub tsev muag tshuaj koj tuaj yeem yuav Reduxine yam tsis muaj tshuaj.
Nyob rau tib lub sijhawm, nws yog qhov yooj yim heev los yuav cov tshuaj no hauv Is Taws Nem.
Reduxin Met, yog siv raws li qhia, muab poob phausCov. Nrog rau cov xwm txheej uas ib tus neeg tsis muaj cov organic rog. Hauv qhov no, qhov tshwm sim ntawm txoj kev kho mob yuav tsum sib txawv.
Tom qab tshawb nrhiav thiab kuaj tus neeg tau siv Reduxin Met, cov kws kho mob cov tshuaj xyuas tau los rau ntawm cov ntaub ntawv hauv qab no:
- Kev ua haujlwm ntawm zaub mov noj thiab kev noj zaub mov kom muaj calorie ntau ntau tau raug txo kom tsawg. Kwv yees li 2.4-3 zaug.
- Feem ntau, sibutramine raug pom zoo los ntawm tib neeg thiab tsis quav tshuaj ntxiv.
- 94.7% ntawm cov tib neeg pom tias lub siab poob qis heev.
- Cov tshuaj no rau qhov poob phaus qhia cov nyhuv feem ntau ruaj khov, uas tib neeg, nws hloov tawm, tswj lub sijhawm ntev haum.
- Thaum noj cov tshuaj no, poob ceeb thawj pom tias yog khoom noj kom zoo.
Vim tias tag nrho cov no, muaj peev xwm kom nrawm nrawm tiav. Txij li ib tus neeg muaj qhov kev pom pom.
Kev txheeb xyuas txog Reduxin Met
Qhov kev kawm ywj siab thiab tshuaj xyuas cov neeg uas tau txiav txim siab Reduxine Met txiav txim siab 95% ua rau tsis qab los, 5% ntawm lawv muaj kev txo nyob rau hauv kev saj thaum noj cov zaub mov uas nyiam ua ntej.
Tom qab siv Reduxine, cov neeg poob phaus hauv cov neeg muaj BMI ntawm 26-31 yog 6.8 kg hauv thawj 4 lub lim tiam ntawm kev siv. Cov neeg uas muaj BMI ntawm 31-39 txo nyob hauv kwv yees 4 lub lis piam 7.9 kg ntawm lawv thawj qhov hnyav. Ntawd yog, kev poob nrawm nrawm dua hauv lub cev tau tiav.
Thaum pib ntawm 3 lub lim tiam ntawm kev siv, 10% ntawm tib neeg tau nqhis dej raws li kev phiv, thiab 12% muaj lub qhov ncauj qhuav me ntsis. Yuav luag 11%, siv nyob rau qee theem yuav tsum nrog nrog cem quav.
4% ntawm cov neeg ntsib xeev siab me, dias taub hau, txob taus, hloov pauv ntawm kev nyiamCov. Hauv 7% ntawm tus neeg mob, muaj feem ntau lub plawv dhia, nce me ntsis ntshav siab, mob taub hau.
nyob hauv kwv yees li 2% ntawm cov neeg mob, cov neeg tau pw los ntawm kev pw tsaug zog ntxhov siab, txob taus, lossis kev poob siab. Feem ntau, kev kuaj xyuas tus neeg mob yog qhov zoo txog cov tshuaj.
Yog tias koj tsis nyeem txog qhov txaus ntshai phiv nyob hauv kev txheeb xyuas uas cog lus los ntawm kev noj tshuaj ntsiav, ces rooj plaub zoo li no. Koj haus ib qho tshuaj ntsiav thiab tom qab ib nrab teev koj tsis xav noj! Tus kheej, Kuv tsis ntxhov siab.
Nyob rau yav tsaus ntuj lub siab sawv, lub taub hau mob, tej zaum los ntawm kev tshaib kev nqhis. Tab sis kuv tsis xav noj. Thiab lub siab yuav ploj mus rau tsuas yog txog 8 teev.
Vim tias kom tsis txhob cheb lub tub yees thaum hmo ntuj, haus cov tshuaj rau noj su.
Siv Reduxin 4 lub hlis, raws li kws kho mob. Kuv cuam tawm qhov hnyav ntawm 15 kg. Tsis muaj kev xav txog kev tshaib plab, vim nws tsuas yog yuav pauv pauv khoom noj, tshem tawm tshaj, tsis txhob noj khoom qab zib thaum yav tsaus ntuj. Kuv xav zoo li cas hauv chav kawm, ib qho tsis zoo yog lub qhov ncauj qhuav. Cia li ntau dua feem ntau haus cov kua.
Kuv txiav txim siab kom poob phaus, tab sis, hmoov tsis, tsis muaj lub zog. Tab sis ib zaug kuv saib kev tshaj tawm thiab nyeem cov kev txheeb xyuas, Kuv xav paub tias vim li cas tsis. Lub qab los noj mov tau ploj mus, muaj qee yam ua rau nkees, qhov hnyav pib ploj mus rau hnub thib tsib, thaum xub thawj sai heev, txog 8 kg, tom qab ntawd qeeb qeeb, feem ntau, rho tawm 15 kg ib hlis.
Reduxin MET thiab Reduxin: dab tsi yog qhov sib txawv, cov kws paub txog cov ntsiab lus
Reduxin MET thiab Reduxin yog cov tshuaj los ntawm tib pawg thiab yog ntawm cov khoom siv roj hlawv.
Txawm hais tias muaj kev sib thooj hauv cov npe, cov tshuaj no muaj ntau qhov sib txawv, thaj chaw muaj zog thiab cim kev siv.
Daim ntawv teev cov contraindications thiab cov kev mob tshwm sim txawv insignificantly.Ua ntej noj ib qho ntawm cov tshuaj no, koj yuav tsum kawm cov lus qhia thiab qhov tob tob ntawm lawv txoj kev siv kom tshem tau qhov hnyav tshaj.
Cov tshuaj no yog dab tsi?
Reduxin thiab Reduxin MET yog qee cov tshuaj muaj zog tshaj plaws uas tuaj yeem hlawv cov rog rog. Cov tshuaj no yog siv rau hauv kev kho kev rog ntawm ntau theem. Hauv cov tsev muag tshuaj, cov tshuaj raug muag raws li cov tshuaj noj. Qhov nuance no vim yog lawv lub zog thiab qhov txwv tsis pub nkag nrog yam tsis muaj kev qhia tshwj xeeb rau kev kho mob.
- ob qho tshuaj yog tshuaj anorexigenic,
- Reduxin MET yog qhov ua tiav Reduxin,
- tshuaj muaj peev xwm tshem tawm kev puas siab puas ntsws rau kev xav tau zaub mov noj,
- ob qho tshuaj yeeb tshuaj yog suav tias yog mob hnyuv.
Kev sib piv ntawm cov nyiaj
Dab tsi yog qhov sib txawv ntawm Reduxin thiab Reduxin MET?
Reduxine muaj nyob hauv daim ntawv tshuaj ntsiav nrog ntau qhov tshuaj ntawm 10 mg thiab 15 mg ntawm cov tshuaj xyaw nquag.
Reduxin MET yog qhov kev npaj hnyav, ib pob khoom muaj ob qho tshuaj - ntsiav tshuaj thiab tshuaj ntsiav. Tus nquag ua hauj lwm hauv cov tshuaj no yog sibutramine.
Koom tes hauv cov khoom npaj muaj:
- microcrystalline cellulose,
- zas xim titanium dioxide,
- nkaws
- patented xiav,
- calcium stearate.
Qhov tshwm sim ua tau
Cov kws tshaj lij txwv tsis pub siv Reduxin MET rau kev ua haujlwm rau lub cev. Cov tshuaj yog tsim los kho cov rog tiv thaiv keeb kwm ntawm ntau yam kab mob.
Yog tias koj noj cov ntsiav tshuaj lossis tshuaj ntsiav nrog lub cev nyiam dhau qhov nyhav dhau los, nws muaj kev pheej hmoo ntawm kev tsim kev phiv ntau heev. Nrog rau kev kho mob raws li cov cim, ob qho tshuaj yeeb tshuaj qhia tau muaj txiaj ntsig zoo.
Reduxin tuaj yeem ua rau hauv qhov muaj qhov hnyav ntawm qhov hnyav hauv cov txheej txheem hauv lub cev hauv lub cev, ua rau lub cev nce ntxiv.
Qhov tshwm sim tau ntawm kev siv tshuaj:
- lub cev hnyav tom qab ib chav kawm ntawm kev kho mob nrog cov tshuaj tsis hloov pauv (cov txheej txheem ntawm tsub zuj zuj ntawm lub cev rog nres),
- feem ntau, qhov hnyav tshwm sim rau qee qhov me me,
- tshem tawm ntawm cov neeg coob ntawm cov phaus ntxiv vim yog tus kheej cov yam ntxwv ntawm lub cev.
Cov txheej txheem ntawm kev txiav txim
Cov txheej txheem ntawm kev ua ntawm Reduxin thiab Reduxin MET nqa tawm raws li ib txoj ntsiab cai, tab sis nrog sib txawv qib ntawm kev siv.
Kev ua ntawm cov tshuaj yog tsom rau tshem tawm lub cev muaj roj thiab yog vim muaj cov yam ntxwv ntawm cov khoom ua haujlwm nquag.
Reduxin MET muaj peev xwm ntxiv ntxiv rau kev tshem tawm cov tsos mob ntawm kev rog lub cev muaj ntshav qab zib. Kev ua tau zoo nyob rau hauv lub cev-rog ntawm cov tshuaj no yog vim qhov sib ntxiv ntawm sibutramine metformin.
Tus txheej txheem ntawm kev ua ntawm cov tshuaj yog cov khoom hauv qab no:
- kev koom tes nyob rau hauv synthesis ntawm serotonin,
- txo hauv cov ntshav qab zib
- kev rov qab noj dhau
- normalization ntawm ntshav qabzib
- tshem tawm ntawm subcutaneous rog,
- tshem cov kua ntau ntawm lub cev,
- qis triglycerides,
- detoxification nyhuv
- cuam tshuam rau xim av adipose cov ntaub so ntswg receptors,
- kev tawm ntawm qee cov kab mob me me los ntawm lub cev,
- ntau zog siv nyiaj los ntawm lub cev,
- kev zom plab zom mov,
- tshem tawm cov khoom lag luam tshaj dhau hwv,
- inhibition ntawm gluconeogenesis nyob rau hauv daim siab.
Reduxin MET muaj lub peev xwm los ua kom muaj txiaj ntsig zoo ntawm lipid metabolism, qeeb rau kev nqus ntawm cov carbohydrates hauv txoj hnyuv, thiab ua rau muaj kev sib xyaw glycogen. Cov yam ntxwv ntxiv ntawm cov tshuaj yog vim yog cov ntsiab lus ntawm metformin hauv nws. Ntxiv rau, cov tshuaj no muaj cov kev kho mob thaum siv los kho cov rog los ntawm ntshav qab zib.
Tus nqi ntawm Reduxine yog qhov nruab nrab ntawm 1600 rubles. Tus nqi ntawm Reduxine MET ncav cuag 2000 rubles. Qhov sib txawv yog vim muaj ntau hom kev tso tawm thiab tus naj npawb ntawm cov khoom hauv cov txheej txheem ntawm cov npaj hauv.Reduxin MET yog txheej ntawm ob lub tshuaj.
Cov nqi tshuaj yuav sib txawv raws thaj chaw. Thaum xaj cov khoom siv online, feem ntau, tus nqi kawg suav nrog tus nqi ntawm tus neeg muag khoom rau xa cov khoom.
Nyob rau lub sijhawm ntawm kev tshaj tawm thiab tshwj xeeb, koj tuaj yeem yuav cov tshuaj ntawm tus nqi qis.
Txoj kev siv
Qhov ntau npaum ntawm qhov tshuaj ntawm Reduxin thiab Reduxin MET yog nqa tawm raws li cov txheej txheem qub.
Ua ntej siv cov tshuaj, nws raug nquahu kom sab laj nrog tus kws kho mob.
Nyob rau ntawm lub cim tshwj xeeb lossis qee tus yam ntxwv ntawm lub cev, qhov ntau thiab cov sijhawm ntawm kev kho mob yuav txawv ntawm cov lus pom zoo los ntawm cov kws tsim khoom hauv cov lus qhia. Piv txwv li, thaum tsis muaj qhov cuam tshuam los ntawm kev tshem tawm qhov hnyav tshaj, cov kws tshaj lij pom zoo txog kev noj ob npaug ntawm Reduxine MET ntsiav tshuaj, thaum muaj pes tsawg tus tsiav tshuaj noj tsis hloov pauv.
Txoj kev siv tshuaj:
- Reduxin yuav tsum noj ib hnub ib zaug hauv ib qho tshuaj ntsiav,
- Reduxine MET tau noj ib hnub ib zaug, ib lub tshuaj ntsiav thiab ntsiav tshuaj ib zaug,
- tsiav tshuaj thiab ntsiav tshuaj tsis tuaj yeem zom,
- tshuaj yuav tsum tau ntxuav nrog ib tug txaus cov dej,
- Tsis txhob noj tshuaj nrog noj mov (qhov ua tau zoo ntawm kev kho tuaj yeem txo qis),
- lub sijhawm ntawm cov chav kawm ntawm kev poob phaus nrog tshuaj yuav tsum tsis pub ntau tshaj peb lub hlis.
Cov kws kho mob xav
Cov kws tshaj lij lees paub qhov kev ua haujlwm zoo ntawm Reduxin thiab Reduxin MET tshuaj kho cov rog. Cov tshuaj no ua rau qee qhov ntawm lub hlwb, ua kom qhov kev xav tau zoo puv nkaus.
Tsis tas li ntawd, cov tshuaj muaj txiaj ntsig zoo rau cov txheej txheem metabolic, tsim kom muaj tus cwj pwm noj kom zoo thiab ua kom nrawm tawg ntawm cov rog.
Cov kws tshaj lij yog lub tswv yim tias tsuas yog tus kws kho mob yuav tsum xaiv cov tshuaj twg yuav tsum tau siv rau tus neeg mob.
Raws li kev xav ntawm cov kws kho mob, cov lus pom hauv qab no tuaj yeem kos tau:
- Reduxin MET ua tau zoo dua li Reduxin vim tias nws nthuav dav,
- Nws yog qhov zoo dua los pib kho kev rog nrog Reduxine, thiab yog tias nws cov txiaj ntsig tsawg, hloov nws nrog cov tshuaj "MET",
- kom tau txais qhov tshwm sim muaj txiaj ntsig, nws yuav tsum tau noj tshuaj tsawg kawg peb lub hlis (txwv tsis pub lub txiaj ntsig yuav yog ib ntus),
- nyob rau hauv tsis muaj cov ntaub ntawv yuav tsum koj pib noj ib yam ntawm cov rog-hlawv tshuaj rau cov rog ntawm koj tus kheej,
- kev siv cov tshuaj thaum tsis muaj kev qhia pom txog kev kho mob ntawm ntau cov kev mob tshwm sim (kiv taub hau, xeev siab, ntuav, tsaug zog lossis pw tsis tsaug zog, cem quav lossis zawv plab, cuam tshuam ntawm lub plab zom mov, hlab plawv thiab lub paj hlwb,
- tshuaj txuam nrog ntau yam contraindications, feem ntau ntawm cov uas tuaj yeem pom tsuas yog nrog kev tshuaj xyuas txhua yam ntawm tus neeg mob,
- yog hais tias Reduxin tsis muab qhov tshwm sim zoo, ces hloov nws nrog Reduxin MET yam tsis tau nrog kws kho mob.
Reduxin meth thiab reduxin: dab tsi yog qhov sib txawv thiab qhov twg zoo dua
Tam sim no, cov tshuaj "Reduxin" nquag siv ua ib qho zoo heev thiab tshwj xeeb tshaj yog ua rau cov rog rog. Hauv kev ua lag luam ntawm cov tshuaj niaj hnub, ib tus tuaj yeem nrhiav Reduxin thiab Reduxin Met, uas txawm hais tias lawv siv rau tib lub hom phiaj, muaj lub sijhawm los khav ntawm lub xub ntiag ntawm qee qhov sib txawv.
Zoo ib yam li lwm yam roj-hlawv tus neeg sawv cev ntawm hom no, ob hom tshuaj no muaj qee qhov nqi ntawm phiv thiab tib lub sijhawm, lawv tuaj yeem tawm hauv qee qhov xwm txheej tshwj xeeb. Hauv kev pom txog qhov no, txhawm rau hais txog qhov sib txawv ntawm ib leeg, ib tus yuav tsum xub paub koj tus kheej nrog rau txhua yam hais los saum toj saud sib cais.
Reduxin Met thiab Reduxin: dab tsi yog qhov sib txawv - Phau Ntawv Qhia Txog Kev Noj Mov thiab Rog Poob
Cov tshuaj "Reduxin" tuaj yeem hu ua ib lub zog ua kom rog rog. Ntawm kev lag luam kws tshuaj koj tuaj yeem nrhiav Reduxin Met thiab Reduxin: qhov sib txawv ntawm cov qauv no rau kev poob phaus, thiab yuav ua li cas coj lawv kom raug?
Cov neeg mob nrhiav kom tau tshem ntawm cov neeg ntxim ntxub yog npaj los ua kev txi rau qhov zoo ntawm lub cev zoo nkauj. Thiab, tib lub sijhawm, Reduxin thiab nws cov lus qhia Reduxin Met muaj ntau cov kev mob tshwm sim thiab ntau yam kev sib tiv.
Cov yam ntxwv ntawm cov tshuaj "Reduxin"
Koj tuaj yeem nkag siab qhov sib txawv ntawm Reduxin Met thiab Reduxin los ntawm kev paub koj tus kheej nrog cov yam ntxwv sib txawv thiab cov cim thaj chaw ntawm cov tshuaj. Hauv ob txoj kev txhim kho no muaj cov sib xyaw sibutramine, uas yog muab cov txheej txheem ntawm kom poob phaus.
Qhov no yog qhov muaj zog anorexigenic tshuaj muaj lub zog zoo nyob rau hauv nruab nrab lub paj hlwb.Cov. Tam sim no, cov tshuaj uas muaj cov khoom siv no tsuas yog muab tshuaj nkaus xwb.
Nws tau muaj pov thawj tias Reduxin tuaj yeem muaj yees ntxiv, yog li nws qhov kev siv yuav tsum muaj kev kuaj mob tshuaj.
Qhov sib txawv ntawm Reduxin thiab Reduxin Met yog dab tsi? Qhov tom kawg yog qhov txuas ntxiv ntawm thawj zaug thiab yog siv rau kev yuam kom poob phaus rau kev kho mob. Kev siv qee yam ntawm cov tebchaw tsuas yog los ntawm qhov zoo nkauj pom xwb.
Kev qhia rau kev siv cov sibutramine-based khoom yog cov rog nrog lub cev nyhav ntawm lub cev thiab cov kab mob hnyav nce hauv cov ntshav qab zib. Txhawm rau kho qhov yooj yim ntawm daim duab, cov tshuaj zoo li no yuav tsis ua haujlwm.
Koj yuav tsum nkag siab tias qhov sib txawv ntawm kev tsim cov tshuaj yeeb yaj kiab kom yooj yim rau kev poob phaus thiab lub zog tsim nrog sibutramine yog loj heev.
Kev siv ntawm "Reduxin" yog ua tau tsuas yog tias qhov txiaj ntsig ntawm qhov kev ua ntawm qhov muaj pes tsawg leeg yuav siab dua qhov kev puas tsuaj los ntawm cov rog dhau los. Kev liam tag nrho rau ntau yam kev sib tw, suav nrog:
- kev mob hlwb
- mob ntsws
- kab mob plawv
- laus lawm
- cev xeeb tub thiab lactation,
- mob siab thiab mob raum,
- organic hom rog,
- ntshav siab
- bulimia leeg.
Kev ceev faj yuav tsum noj "Reduxin" rau cholelithiasis, ntshav txhaws, arrhythmias thiab lwm yam teeb meem uas cuam tshuam. Tus kws kho mob uas tuaj koom tuaj yeem sau tshuaj rau hom tshuaj no tsuas yog tom qab kuaj xyuas tus mob ntawm tus neeg mob thiab qhov xwm txheej zoo ntawm kev kho mob.
Reduxin Met thiab Reduxin: dab tsi yog qhov sib txawv siv
Reduxin Met yog qhov kev tsim kho tshiab. Nov yog cov tshuaj sib txuam ua ke ntawm ob qho tshuaj:
- tsiav tshuaj nrog sibutramine - pab txhawb rau kev rog, tiv thaiv kev qab los noj mov, pab txhawb kev noj zaub mov,
- ntsiav tshuaj nrog metformin - ib qho hypoglycemic los ntawm chav kawm biguanide. Nws muaj cov rog ua cov rog.
Reduxin Met tau pom tias muaj txiaj ntsig zoo tshaj plaws hauv kev kho cov rog nrog ntshav qab zib. Metformin pab txhim kho cov insulin receptor rhiab heev thiab pab txhawb nqa kom muaj suab thaj.
Qhov tshuaj txhua hnub thaum pib kho yog 1 lub tshuaj metformin thiab 1 tshuaj ntsiav ntawm sibutramine. Lawv tau noj tib lub sijhawm, sib txuas nrog kev haus tshuaj nrog kev noj zaub mov.
Yog tias tsis muaj tshwm sim li 2 lub lis piam, kev noj tshuaj ntawm metformin ntau npaum li ob npaug.
Kev siv tshuaj nrog ob qho tshuaj yuav tsis tuaj yeem lees paub yam tsis muaj kev saib xyuas mob. Nyob rau tib lub sijhawm ua kev noj tshuaj, ua ib qho kev noj haus ib leeg thiab ua si lub cev, ua si aerobic ntau, nws yog kws kho.
Thaum muaj ib qho dhau hwv lawm, kev tsis txaus siab ntawm cov hlab ntsha hlwb feem ntau tau pom, uas yog: pw tsis tsaug zog, ntxhov siab, mob taub hau, kiv taub hau.
Qhov sib txawv hauv tus nqi yog tseem tam sim no. Nrog rau kev sib npaug sib xyaw ntawm sibutramine, Reduxin Met yuav kim dua.
Reduxin tau ntsib - kev tshuaj xyuas txog daim ntawv thov, cov lus qhia rau kev siv tshuaj rau qhov poob phaus thiab tus nqi
Raws li cov neeg siv tshuaj xyuas ntawm cov tshuaj Reduxin Met, coj raws li kws kho mob tau teev tseg, daim ntawv thov ua rau cov txiaj ntsig tsis txaus ntseeg thiab yog, tib lub sijhawm, pheej yig.Txawm li cas los xij, zoo li ib yam tshuaj twg, koj yuav tsum siv nws kom zoo thiab ua raws cov lus qhia. Reduxin muaj ntau cov kev tiv thaiv, uas tsis tsuas yog yuav pab txhawb kom yuag poob, tab sis kuj ua rau muaj kev phom sij.
Cov tshuaj sib xyaw ua ke ntawm cov tshuaj Reduxin
Txhawm rau txiav txim siab qhov yuav tsum tau noj tshuaj tshwj xeeb rau qhov poob phaus, koj yuav tsum paub dab tsi hauv nws cov muaj pes tsawg leeg. Reduxine muaj nyob rau ob hom: tsiav tshuaj thiab ntsiav tshuaj. Lawv muaj cov qauv zoo sib xws ntawm kev nqis tes ua thiab koj tuaj yeem xaiv lwm qhov kev xaiv tsim nyog rau kev txais tos lossis siv lawv ib txhij. Cov lus sib xyaw ntawm Reduxine nyob rau hauv ob daim ntawv yog yooj yim, tab sis nws txawv heev.
Daim foos Met, zoo li Reduxin-Goldline analogue, muaj sibutramine hauv nws cov lus. Sab hauv ib lub tshuaj ntsiav, nws cov ntsiab lus mus txog qhov ntau npaum ntawm 15 mg.
Qhov khoom no, uas yog hauv cov tshuaj uas pab kom yuag poob, tsim kom muaj kev xav zoo rau lub sijhawm ntev, tsis pub ib tus neeg ua dhau cai.
Reduxine, cov tsiav tshuaj uas muaj ntxhiab tsw qab zoo nkauj nyob sab nraud nrog cov hmoov zoo sab hauv, muaj nyob hauv cov ntawv ntim los ntawm 30 daim. Lub plhaub yog tsim raws ntawm gelatin, yog li nws yaj zoo tom qab kev noj haus.
Reduxin noj tsis yog tsuas yog ua rau poob phaus, tab sis kuj yuav pab tiv thaiv mob ntshav qab zib, uas feem ntau ua rau kev rog. Txoj kev kho yog nrog tshuaj yeeb tshuaj hu ua metformin.
Nws yuav tsum tau ua nrog ceev faj, nruj me ntsis raws li cov lus qhia. Cov tshuaj Reduxin, cov tshuaj uas muaj 850 mg ntawm metformin, raug muag hauv cov chaw muag tshuaj hauv cov pob 10 lossis 60 daim.
Yog tias vim li cas koj thiaj li txiav txim siab pib noj koj tus kheej, nco ntsoov tias cov tshuaj txhua hnub ntawm cov tshuaj yuav tsum tsis pub tshaj 2550 mg.
Ib qho tshuaj yuav tsum noj raws li qee qhov txheej txheem, kom nws ua haujlwm zoo thiab tsis ua mob rau lub cev.
Cov Lus Qhia Reduxine Met tau hais tias thaum xub thawj koj yuav tsum haus cov tshuaj no 1 tshuaj ntsiav thiab 1 ntsiav tshuaj ib hnub ib zaug, ntxuav nrog dej.
Ntxiv mus, nws yog ib qho tsim nyog los ua kom hnyav dua thiab yog tias, tom qab 2 lub lis piam, muaj qhov ua kom tsis muaj zog lossis nws tsis muaj nyob txhua lub sijhawm, tom qab ntawd qhov koob tshuaj nce ntawm ob yog ua tau.
Kev ntsuas rau siv
Sibutramine rau kom poob phaus yog ib yam zoo li panacea, vim tias nws tsuas yog txwv tsis pub ua ntau dhau, txo qhov qab los noj mov.
Txawm li cas los xij, kev qhia rau kev siv Reduxine Met tsuas yog thawj theem ntawm kev rog, thaum lawv muaj kev cuam tshuam tiag ntawm qhov xwm txheej.
Ntxiv rau, yog tias lub cev nyhav dhau los, uas tuaj yeem tawm tsam nrog cov pluas noj, nrog cov ntshav qab zib, tom qab ntawd koj yuav tsum tau ntsib Met. Nrog rau tus kab mob no, Reduxine yuav tsum noj nkaus xwb hauv cov qauv tshuaj.
Tus txheej txheem ntawm kev ua ntawm Reduxin
Muaj peb hom kev tshaib plab thiab tsuas yog ib qho ntawm lawv tiag tiag hauv lub cev nqaij daim tawv. Kev paub txog tib cov cuav tsis muaj qhov qab los noj mov, lub cev hloov mus rau qhov tsis zoo, yog tias nws tsis muaj peev xwm txaus siab rau qhov xav tau.
Tus txheej txheem ntawm kev ua ntawm Reduxin yog tias Met, raws li hom kev txwv tsis pub cuam tshuam, cuam tshuam txog kev sib txuas ntawm cov serotonin, uas ua rau muaj kev zoo siab.
Qhov no pab ua cov khoom tseem ceeb ua haujlwm tau zoo dua: sibutramine, uas ua rau tsis qab los noj mov, lossis metformin, uas txo cov ntshav qab zib thiab hloov cov ntshav qabzib.
Yuav ua li cas noj Reduxine
Cov tshuaj tiv thaiv dab tsi lossis qhov tshuaj no yuav ua rau muaj kab mob dab tsi. Muaj kev pheej hmoo yuav tau txais qhov tsis zoo lub txim. Yog tias koj noj Reduxine kom raug, ces kev phiv yuav zam tau. Tsis txhob pib nrog cov tshuaj loj, txwv koj tus kheej kom 1 tshuaj ntsiav thiab 1 ntsiav tshuaj hauv ib hnub.
Txhawm rau kom tsis txhob ntsib teeb meem nrog txoj hnyuv, cov lej ntawm cov khoom yuav tsum tsis pub tshaj 3 daim thiab koj yuav tsum coj lawv thaum nruab hnub, soj ntsuam cov kev cuam tshuam. Nws yog ib qho tseem ceeb uas yuav tsum nco ntsoov tias Reduxin thiab cawv tsis sib xws. Xws li kev sib xyaw ua ke tuaj yeem ua rau qaug cawv nrog txhua qhov teeb meem.
Reduxin Nqe Nqe
Nws yog qhov zoo dua los yuav cov tshuaj hauv cov khw muag tshuaj, tab sis koj tuaj yeem xaj los ntawm catalog thiab yuav hauv khw online.Txawm li cas los xij, hauv rooj plaub thib ob, hloov chaw, piv txwv li, cov khoom ntim tsis zoo yuav nyuaj dua. Cov twj siv yog qhov pheej yig, tab sis qhov no tsis txhais tau tias koj yuav tsum tau tshuaj nws tus kheej thiab tsis txhob sab laj nrog kws kho mob. Tus nqi ntawm Reduxin Met sib txawv ntawm cov tshuaj thiab nws cov ntim:
Hom | Kom muaj nuj nqis | Nqi hauv rubles |
Sibutramine 10 mg tsiav tshuaj + 158.5 mg cellulose thiab 850 mg ntsiav tshuaj | 30 tsiav tshuaj thiab 60 ntsiav tshuaj | 2983 |
Sibutramine 15 mg tsiav tshuaj + 153.5 mg cellulose thiab 850 mg ntsiav tshuaj | 30 tsiav tshuaj thiab 60 ntsiav tshuaj | 1974 |
KVN lub hnub qub Olga Kortunkova - Zaj dab neeg tsis tseeb ntawm poob 32 kg!
Nyeem ntxiv >>>
Victoria Romanets los ntawm Lub Tsev 2 tau hais txog qhov tsis hnyav txog 19 kg hauv ib lub hlis!
Nyeem nws zaj dab neeg >>>
Polina Gagarina - Koj tuaj yeem poob ceeb thawj los ntawm 40 phaus txawm tias muaj qhov tsis zoo los yog ntau caj ces. Kuv paub rau kuv tus kheej!
Ntau cov lus qhia ntxiv >>>
OneTwoSlim yog ib qho kev ua ke zoo tagnrho rau kev poob phaus, tsim tawm mus rau hauv tus account tib neeg biorhythms!
Dietonus - COV NTAUB NTAWV QHIA TXOG KEV NCAJ NCEES RAWS LI 10 KG FAT HAUV 2 LUB HLIS!
Tso tawm daim ntawv, muaj pes tsawg leeg thiab ntim khoom
Teeb: 850 mg ntsiav tshuaj + 10 mg tsiav tshuaj + 158.5 mg
Ntsiav tshuaj oval biconvex dawb lossis yuav luag dawb nrog lub thais ntawm ib sab.
1 tab | |
metformin hydrochloride | 850 mg |
Cov neeg siv: microcrystalline cellulose - 25,5 mg, croscarmellose sodium - 51 mg, dej ntshiab - 17 mg, povidone K-17 (polyvinylpyrrolidone) - 68 mg, magnesium stearate - 8,5 mg.
10 Pcs. - blister packs (aluminium / PVC) (2) - pob cov duab los qhia.
10 Pcs. - blister packs (aluminium / PVC) (6) - pob cov duab los qhia.
Cov tshuaj ntsiav Zaj 2 yog xiav, cov ntsiab lus ntawm cov tshuaj ntsiav yog xim dawb lossis dawb hmoov nrog lub zas daj me ntsis.
1 lub kaus mom. | |
sibutramine hydrochloride monohydrate | 10 mg |
microcrystalline cellulose | 158,5 mg |
Cov neeg siv pauv: calcium stearate - 1.5 mg.
Cov lus sib xyaw ntawm cov tshuaj ntsiav plhaub: titanium dioxide - 2%, zas azorubine - 0.0041%, xim xiav pob zeb xiav - 0.0441%, gelatin - txog 100%.
10 Pcs. - blister packs (aluminium / PVC) (1) - pob cov duab los qhia.
10 Pcs. - blister packs (aluminium / PVC) (3) - pob cov duab los qhia.
Cov teeb tau ntim rau hauv pob duab los ntawm 20 lossis 60 ntsiav tshuaj (metformin) thiab 10 lossis 30 tsiav tshuaj (sibutramine + microcrystalline cellulose) hauv pob blister.
Teeb: 850 mg ntsiav tshuaj + 15 mg tsiav tshuaj + 153.5 mg
Ntsiav tshuaj oval biconvex dawb lossis yuav luag dawb nrog lub thais ntawm ib sab.
1 tab | |
metformin hydrochloride | 850 mg |
Cov neeg siv: microcrystalline cellulose - 25.5 mg, croscarmellose sodium - 51 mg, dej ntshiab - 17 mg, povidone (polyvinylpyrrolidone) - 68 mg, magnesium stearate - 8,5 mg.
10 Pcs. - blister packs (aluminium / PVC) (2) - pob cov duab los qhia.
10 Pcs. - blister sawb ntim (aluminium / PVC) (6) - pob ntawm cardboard ..
Cov tshuaj ntsiav Zaj 2 yog xiav, cov ntsiab lus ntawm cov tshuaj ntsiav yog xim dawb lossis dawb hmoov nrog lub zas daj me ntsis.
1 lub kaus mom. | |
sibutramine hydrochloride monohydrate | 15 mg |
microcrystalline cellulose | 153,5 mg |
Cov neeg siv pauv: calcium stearate - 1.5 mg.
Cov lus sib xyaw ntawm cov tshuaj ntsiav plhaub: titanium dioxide - 2%, xaim xim xiav xiav - 0.2737%, gelatin - txog 100%.
10 Pcs. - blister packs (aluminium / PVC) (1) - pob cov duab los qhia.
10 Pcs. - blister packs (aluminium / PVC) (3) - pob cov duab los qhia.
Cov teeb tau ntim rau hauv pob duab los ntawm 20 lossis 60 ntsiav tshuaj (metformin) thiab 10 lossis 30 tsiav tshuaj (sibutramine + microcrystalline cellulose) hauv cov hlwv pob.
Pharmacological kev txiav txim
Reduxin Met muaj ob yam tshuaj sib txawv hauv ib pob: ib tus neeg sawv cev hypoglycemic rau kev tswj hwm qhov ncauj ntawm ib pawg ntawm cov tshuaj loj nyob hauv cov ntsiav tshuaj ntau npaum li cas - metformin, thiab cov tshuaj rau kev kho mob rog nyob rau hauv tshuaj ntsiav muab tshuaj uas muaj sibutramine thiab microcrystalline cellulose.
Qhov ncauj tshuaj hypoglycemic los ntawm cov pab pawg biguanide. txo hyperglycemia, yam tsis muaj kev coj ua rau kev txhim kho hypoglycemia. Tsis zoo li sulfonylurea derivatives, nws tsis txhawb kev tiv thaiv insulin secretion thiab tsis ua rau muaj kev cuam tshuam hypoglycemic hauv cov neeg noj qab haus huv. Tsub qhov rhiab heev ntawm peripheral receptors rau insulin thiab kev siv cov kua nplaum los ntawm lub hlwb.
Nws inhibits gluconeogenesis nyob rau hauv daim siab. Ncua kev nqus ntawm cov carbohydrates hauv cov hnyuv.Metformin stimulates glycogen synthesis los ntawm kev ua ntawm glycogen synthase. Tsub kom muaj peev xwm thauj tau txhua yam ntawm cov khoom thauj ua kua roj ntau dua. Tsis tas li ntawd, nws muaj txiaj ntsig zoo rau lipid metabolism: nws txo qis tag nrho cov roj cholesterol, LDL thiab triglycerides.
Thaum noj cov tshuaj metformin, tus neeg mob lub cev hnyav dua li qub tseem ruaj khov lossis txo qis.
Nws yog cov prodrug thiab exerts nws cov nyhuv hauv vivo vim muaj cov metabolites (thawj thiab theem nrab amines) uas inhibit qhov rov kho dua ntawm monoamines (serotonin, norepinephrine thiab dopamine).
Kev nce ntxiv hauv cov ntsiab lus ntawm neurotransmitters hauv cov lus sib tham tau nce qhov kev ua haujlwm ntawm central serotonin 5HT receptors thiab adrenoreceptors, uas ua rau muaj qhov nce ntawm qhov kev xav ntawm qhov muaj txhij txhua thiab txo qis ntawm kev thov zaub mov, nrog rau kev nce hauv thermal ntau lawm. Los ntawm kev ua kom ncaj qha β3-adrenergic receptors, sibutramine ua rau ntawm daim ntaub adipose xim av.
Ib qho kev txo qis ntawm lub cev qhov hnyav yog nrog los ntawm kev nce ntxiv ntawm qhov kev xav ntawm HDL hauv cov ntshav dej thiab cov roj triglycerides txo qis, tag nrho cov roj (cholesterol), LDL thiab uric acid.
Sibutramine thiab nws cov metabolites tsis cuam tshuam rau qhov kev tso tawm ntawm monoamines, tsis inhibit MAO, tsis muaj kev sib raug zoo rau ntau tus neurotransmitter receptors, suav nrog serotonin (5-HT1, 5-HT1A, 5-HT1B, 5-HT2C), adrenergic receptors (β1, β2, β3 , α1, α2), dopamine (D1, D2), muscarinic, histamine (H1), benzodiazepine thiab glutamate NMDA receptors.
Nws yog ib qho enterosorbent, muaj kev ua kom lub siab ntev thiab muaj cov txiaj ntsig tsis huv uas tsis paub meej. Nws khi thiab tshem tawm ntau cov kab mob me me, cov khoom lag luam ntawm lawv cov kev ua haujlwm tseem ceeb, co toxins ntawm exogenous thiab endogenous xwm, kev ua xua, xenobiotics, thiab ntxiv rau qee yam dhau ntawm qee yam khoom hauv metabolic thiab metabolites lub luag haujlwm rau kev loj hlob ntawm endogenous toxicosis.
Ib txhij siv metformin thiab sibutramine nrog microcrystalline cellulose nce kho kom zoo dua ntawm kev sib xyaw ua ke siv nyob rau hauv cov neeg mob rog thiab hom ntshav qab zib hom 2.
Noj ntau dhau
Cov tsos mob nrog kev siv cov tshuaj metformin hauv ib koob ntawm 85 g (42.5 lub sijhawm qhov siab tshaj qhov niaj hnub): tsis muaj kev tiv thaiv kabmob ntshav qab zib tsawg, txawm li cas los xij, kev txhim kho ntawm cov kab mob lactic acidosis tau sau tseg. Noj ntau tshaj qhov sib txuam lossis cov kev pheej hmoo cuam tshuam yuav ua rau kev loj hlob ntawm cov kab mob lactic acidosis.
Kev Kho Mob: Nyob rau hauv cov ntaub ntawv ntawm cov cim ntawm lactic acidosis, kev kho mob nrog cov tshuaj yuav tsum tau nres tam sim ntawd, tus neeg mob mus pw hauv tsev kho mob sai sai thiab, tau txiav txim siab qhov concentration ntawm lactate, qhia meej kev kuaj mob. Qhov ua tau zoo tshaj plaws los tshem tawm lactate thiab metformin tawm ntawm lub cev yog hemodialysis. Cov kev mob tshwm sim kuj yog nqa tawm.
Nws tsis muaj cov pov thawj tsawg heev txog kev siv tshuaj sibutramine ntau dhau.
Cov tsos mob tachycardia, ntshav nce siab, mob taub hau, kiv taub hau. Qhia rau koj tus kws kho mob yog tias koj xav tias noj ntau dhau.
Kev Kho Mob: Tsis muaj kev kho tshwj xeeb lossis kev siv tshuaj tua tus kheej. Nws yog ib qho tsim nyog yuav tsum ua cov kev ntsuas dav dav - kom ntseeg tau tias kev ua pa pub dawb, saib xyuas qhov xwm txheej ntawm CVS, thiab tseem, yog tias tsim nyog, nqa tawm cov kev txhawb nqa cov tsos mob txhawb nqa. Kev tswj hwm sijhawm kom ua haujlwm ntawm cov pa roj carbon ntau, nrog rau lub plab zom zaub mov, tuaj yeem txo qhov kom tsawg ntawm sibutramine hauv lub cev. Cov neeg mob uas muaj ntshav siab thiab tachycardia tuaj yeem raug tshuaj beta-blockers. Qhov ua tau zoo ntawm kev yuam diuresis lossis hemodialysis tseem tsis tau tsim. Yog tias muaj kev noj ntau dhau, siv tshuaj tam sim ntawd Reduxin ® Met.
Cov lus qhia tshwj xeeb
Cov kab mob lactic acidosis. Cov kab mob lactic acidosis yog ib qho mob uas tsis tshua muaj tab sis mob hnyav (kev tuag siab rau thaum tsis muaj kev kho mob thaum maj nrawm) qhov teeb meem uas yuav tshwm sim vim kev txuam nrog metformin. Cov kab mob ntawm cov kab mob lactic acid thaum noj cov tshuaj metformin feem ntau tshwm sim rau cov neeg mob ntshav qab zib mellitus uas mob raum tsis ua haujlwm.Lwm yam kev pheej hmoo cuam tshuam yuav tsum tau txiav txim siab, xws li decompensated ntshav qab zib mellitus, ketosis, kev yoo mov ntev, haus dej cawv, lub siab ua haujlwm, thiab tej yam kev mob cuam tshuam nrog mob hypoxia. Qhov no tuaj yeem pab txo qis qhov mob tshwm sim ntawm cov kab mob lactic acidosis.
Txoj kev pheej hmoo ntawm kev tsim cov kab mob lactic acidosis nrog cov tsos mob ntawm qhov tsis muaj qhov cim, xws li mob leeg, nrog cov tsos mob dyspeptic, mob plab thiab asthenia hnyav yuav tsum tau txiav txim siab. Lactic acidosis yog tus cwj pwm mob los ntawm acidotic ua tsis taus pa, mob plab thiab hypothermia ua raws li los ntawm coma. Kev kuaj kab mob ntsuas yog qhov txo qis hauv cov ntshav pH (qis dua 7.25), cov ntsiab lus lactate hauv ntshav ntau dua 5 mmol / l, qhov kev tso tawm ntau thiab qhov lactate / pyruvate piv. Yog tias xav tias tsam tus kab mob metabolic acidosis, nws yog ib qho tsim nyog kom tsum tsis txhob noj cov tshuaj thiab sab laj nrog kws kho mob tam sim ntawd.
Kev phais mob Kev siv cov tshuaj Reduxin ® Met yuav tsum tau tsum tsis txhob txuas ntxiv 48 teev ua ntej lub sijhawm npaj ua haujlwm phais thiab tuaj yeem txuas ntxiv tsis pub dhau 48 teev tom qab, muab hais tias thaum lub sijhawm kuaj mob lub raum ua haujlwm tau lees paub tias tsis muaj dab tsi.
Raum muaj nuj nqi. Txij li thaum metformin raug tso tawm los ntawm lub raum, ua ntej pib Reduxin ® Met thiab ua ntu zus tsis tu ncua, nws yuav tsum txiav txim siab Cl creatinine: tsawg kawg 1 zaug hauv ib xyoos hauv cov neeg mob uas lub raum tsis ua haujlwm thiab 2-4 zaug hauv ib xyoos hauv cov neeg laus, thiab cov neeg mob nrog Cl creatinine ntawm NGN.
Kev xyuam xim tshwj xeeb yuav tsum tau siv thaum muaj peev xwm ua rau lub raum ua rau cov neeg laus laus, thaum siv cov tshuaj tiv thaiv kab mob, diuretics lossis NSAIDs. Cov neeg mob yuav tsum tau qhia mus ntxiv rau kev noj zaub mov nrog ib qho txawm tias kom tsawg ntawm carbohydrates thoob plaws ib hnub. Tus neeg mob rog rog siab tshaj qhia tias lawv yuav tsum ua raws cov zaub mov muaj calorie tsawg (tab sis tsis tsawg dua 1000 kcal / hnub).
Nws raug nquahu tias cov kev sim ntsuas niaj zaus yuav tsum ntsuas saib ntshav qab zib.
Qhov ceeb toom tau hais qhia thaum siv Reduxin ® Met sib xyaw ua ke nrog cov tshuaj insulin lossis lwm yam tshuaj tua kabmob (suav nrog sulfonylurea derivatives, repaglinide).
Kev kho mob nrog Reduxin ® Met yuav tsum tau ua tawm los ntawm txoj kev kho kom zoo rau lub cev yuag tom qab kev saib xyuas ntawm tus kws kho mob nrog cov kev paub dhau los kho kev rog. Cov kev kho nyuaj nyuaj siab suav nrog ob qho tib si kev hloov pauv ntawm kev noj zaub mov zoo thiab kev ua neej, thiab kev ua kom lub cev muaj zog ntxiv. Ib qho tseem ceeb ntawm kev kho mob yog kev tsim kom muaj qhov kev ntsuas ua ntej kom muaj kev hloov pauv tsis tu ncua ntawm kev noj zaub mov zoo thiab kev ua neej, uas tsim nyog los tswj kev ua kom tiav hauv kev txo lub cev hnyav txawm tias tom qab tshuaj kho tsis nres. Raws li ib feem ntawm kev kho mob nrog Reduxin ® Met, cov neeg mob yuav tsum hloov pauv lawv lub neej thiab kev coj noj coj ua kom tom qab kev kho tiav tiav lawv paub tseeb tias kev ua tiav ntawm kev txo lub cev hnyav tau ceev. Cov neeg mob yuav tsum nkag siab meej tias kev tsis ua raws li cov kev cai no yuav ua rau nce lub cev hnyav dua thiab rov mus ntsib tus kws kho mob uas koom nrog.
Hauv cov neeg mob noj tshuaj Reduxin ® Met, nws yog qhov tsim nyog ntsuas ntsuas ntshav siab thiab lub plawv dhia. Hauv thawj 3 lub hlis ntawm kev kho mob, cov kev ntsuas no yuav tsum tau soj ntsuam txhua 2 asthiv, thiab tom qab ntawd txhua hli. Yog tias thaum kuaj ob zaug sib law liag nce lub plawv dhia thaum so ≥10 neeg ntaus / min lossis CAD / DBP ≥10 hli Hg kuaj pom , koj yuav tsum tsum tsis kho. Hauv cov neeg mob nrog kev mob ntshav siab, hauv leej, tawm tsam keeb kwm ntawm kev tiv thaiv kabmob ntshav, ntshav siab ≥145 / 90 hli. Hg qhov kev tswj hwm no yuav tsum tau nqa tawm tshwj xeeb tshaj yog thiab, yog tias tsim nyog, ntawm cov sijhawm luv. Hauv cov neeg mob uas cov ntshav siab ob zaug thaum ntsuas ntsuas ntau tshaj 145/90 hli Hg. , kev kho mob nrog Reduxin ® Met yuav tsum raug ncua (saib ntu "Sab Cim", Los ntawm CCC).
Kev siv cov metformin yog contraindicated nyob rau hauv mob lub plawv tsis ua haujlwm thiab lub plawv tsis ua hauj lwm nrog cov ntshav tsis khov. Hauv cov neeg mob uas muaj mob CHF, noj Reduxin ® Met ua cov kev tiv thaiv hypoxia thiab lub raum tsis ua haujlwm, cov neeg mob no yuav tsum tau soj ntsuam lub plawv thiab lub raum kev ua haujlwm tsis tu ncua. Hauv cov neeg mob uas pw tsaug zog apnea syndrome, nws yog ib qho tsim nyog yuav tau ua tib zoo saib xyuas ntshav siab.
Kev saib xyuas tshwj xeeb yuav tsum tau tswj hwm kev siv tshuaj ib txhij uas nce QT luv. Cov tshuaj no suav nrog H blockers.1receptors (astemizole, terfenadine), tshuaj antiarrhythmic uas nce QT ntu sij hawm (amiodarone, quinidine, flecainide, mexiletine, propafenone, sotalol), mob plab hnyuv kom muaj zog cisapride, pimozide, sertindole thiab tricyclic antidepressants. Qhov no kuj tseem siv tau rau cov xwm txheej uas tuaj yeem ua rau qhov nce QT ntau ntxiv, xws li hypokalemia thiab hypomagnesemia (saib "Kev Sib Hloov").
Lub sijhawm nruab nrab ntawm kev noj MAO inhibitors (suav nrog furazolidone, procarbazine, selegiline) thiab Reduxine ® Met yuav tsum yog tsawg kawg 2 lub lis piam. Txawm hais tias tsis muaj kev sib txuas tau tsim los ntawm kev noj sibutramine thiab kev txhim kho ntawm thawj lub ntsws ntsig, los ntawm kev paub txog kev pheej hmoo ntawm pawg tshuaj no, nrog kev tshuaj xyuas mob niaj zaus, tshwj xeeb yuav tsum them rau cov tsos mob xws li mob qog ua pa (ua pa tsis ua haujlwm), mob hauv siab thiab o ntawm ob txhais ceg.
Yog tias koj hla lub koob tshuaj Reduxin ® Met, koj yuav tsum tsis txhob noj ob npaug ntawm cov tshuaj hauv lub koob tshuaj tom ntej, nws raug nquahu kom koj yuav tsum noj cov tshuaj ntxiv raws li lub sijhawm tau teev tseg.
Lub sijhawm siv ntawm Reduxin ® Met yuav tsum tsis pub tshaj 1 xyoos.
Nrog rau kev siv sibutramine thiab lwm yam SSRIs, muaj kev pheej hmoo los ntshav ntau ntxiv. Hauv cov neeg mob predisposed los ntshav, nrog rau kev noj tshuaj uas cuam tshuam hemostasis lossis platelet muaj nuj nqi, sibutramine yuav tsum siv nrog ceev faj.
Txawm hais tias cov ntaub ntawv tshawb fawb txog kev quav tshuaj rau sibutramine tsis muaj, nws yuav tsum paub tseeb tias puas muaj qee yam kev quav yeeb tshuaj hauv tus neeg mob keeb kwm thiab mob siab rau qhov tshwm sim ntawm kev siv tshuaj yeeb.
Kev siv cov tshuaj nyob rau hauv cov neeg mob ntshav qab zib tau pom zoo nyob rau hauv muaj cov kev pheej hmoo ntxiv rau kev txhim kho pom tseeb 2 mob ntshav qab zib mellitus, uas suav nrog cov hnub nyoog qis dua 60 xyoo, BMI ntau dua 30 kg / m 2, keeb kwm mob ntshav qab zib hauv lub cev, tsev neeg keeb kwm ntawm cov ntshav qab zib hauv cov txheeb ze ntawm thawj kab ke , nce concentration ntawm triglycerides, txo qis ntawm HDL cov roj cholesterol, ntshav siab.
Cuam tshuam rau kev muaj peev xwm tsav tsheb thiab tshuab. Kev Siv Reduxine ® Met yuav txwv koj lub peev xwm tsav tsheb thiab cov twj. Thaum lub sijhawm siv cov tshuaj Reduxin ® Met, kev saib xyuas yuav tsum tau saib xyuas thaum tsav tsheb thiab koom nrog lwm cov kev phom sij uas yuav tsum muaj kev saib xyuas ntau dua thiab ceev ntawm cov kev tiv thaiv psychomotor.
Chaw tsim tshuaj paus
Chaw nyob raug cai: 445351, Russia, Samara Cheeb Tsam, Zhigulevsk, ul. Xuab zeb, 11.
Chaw nyob ntawm qhov chaw ntau lawm: 445351, Russia, Samara Cheeb Tsam, Zhigulevsk, ul. Cov tsim dej siv dej, 6.
Tel./fax: (84862) 3-41-09, 7-18-51.
Chaw nyob thiab naj npawb xov tooj ntawm cov koom haum muaj cai rau kev tiv toj (tsis txaus siab thiab tsis txaus siab): LLC PROMOMED RUS. 105005, Russia, Moscow, ul. Malaya Pochtovaya, 2/2, p. 1, pom. 1, chav nyob 2.
Xov Tooj: (495) 640-25-28.
Uas yog pheej yig dua
Ntau tus neeg tsom tsis yog tsuas yog nyob rau thaj chaw ntawm cov tshuaj, tab sis kuj rau lawv cov nqi. Reduxin Met yuav luag 2 npaug kim kim tshaj li ntawm cov tshuaj muaj pab rau poob phaus. Qhov no yog vim muaj kev ua tau zoo dua thiab muaj cov tso cai ntxiv ib ntsiav tshuaj. Tab sis cov kws txawj hais tias koj yuav tsum tsis txhob coj mus rau hauv tus nqi tsuas yog qhov txawv ntawm tus nqi.Thaum xaiv cov tshuaj, koj yuav tsum tsom mus rau qhov ntsuas.
Qhov twg yog qhov zoo dua: Reduxin Met lossis Reduxin
Nws yog tsis yooj yim sua kom teb cov lus tsis meej rau lo lus nug ntawm cov tshuaj twg zoo dua. Rau feem ntau cov neeg mob rog, cov kev xaiv classic zoo dua. nws yog qhov pheej yig dua thiab muaj kev nyab xeeb dua. Nrog rau kev txhim kho cov ntshav qab zib hom 2, koj yuav tsum xaiv cov tshuaj cim "Met" kom ua hauj lwm zoo dua thiab tsim tshwj xeeb rau cov tib neeg tsis muaj cov metabolism hauv lub cev.
Nws puas tuaj yeem hloov tau ib cov tshuaj nrog lwm
Nws yog qhov tsim nyog hloov tshuaj ib qho nrog lwm tus, tab sis hauv kev coj ua, cov kws kho mob tsis qhia ua qhov no. Kev hloov pauv tau yog tias ib qho ntawm cov tshuaj tsis muag, thiab kev kho yuav tsum tau pib tam sim ntawd. Hauv qhov no, ntau npaum yuav tsum tau kho. Tsuas yog tus kws kho mob yuav tsum xaiv cov koob tshuaj ntawm cov tshuaj.
Qhov kev hloov ntawm Reduxine mus rau ib qho piv nrog qhov cim "Met" yog ua tau yog tias kev kho mob tsis tau zoo txaus. Thaum tom qab ib hlis ntawm kev noj cov tshuaj, qhov hnyav poob qis dua 5%, tus kws kho mob tshwj xeeb qhia kev hloov kho txoj kev kho mob. Hauv qhov no, koj tuaj yeem nce ntau npaum lossis pib noj tshuaj muaj zog dua.
Txoj kev hloov ntawm Reduxine Met mus rau classic yog ua tau yog tias cov tshuaj ua rau muaj kev phiv ntau heev. Tus neeg mob qee zaum ua xua rau metformin. Rau cov neeg zoo li no, kev noj tshuaj li niaj zaus roj-hlawv tshuaj ua rau txoj kev xaiv.
Kev tshuaj xyuas ntawm cov neeg mob thiab poob phaus
Anna, 27 xyoo, Astrakhan
Reduxin tau raug qhia los ntawm tus phooj ywg uas poob 12 kg rau nws hauv ob peb lub hlis. Kuv tau mus rau tus kws kho mob, dhau qhov kev kuaj xyuas thiab pib haus tshuaj. Cov nyhuv yog, thiab zoo heev. Qhov hnyav tawm hauv 2 lub hlis. Daim duab nyias nyias tseem nyob deb, tab sis qhov pib tau tsim. Kuv npaj txiav haus cov tsiav tshuaj hauv ib hlis thiab txuas ntxiv kom poob ceeb thawj ntawm kuv tus kheej.
Julia, 47 xyoo, Kazan
Reduxin Met tsis nyiam. Kuv lub taub hau tau kiv tom qab noj tas, muaj kev qaug zog. Nws tau raug tshuaj vim tias muaj cov neeg rog ntau dhau. Tom qab ib lub lim tiam ntawm kev nkag mus, nws tau tig mus rau nws tus kws kho mob thiab nws pom zoo hloov mus rau Reduxin. Txhua yam zoo nrog nws. Kuv haus 6 lub hlis thiab poob 23 kg. Kuv qhia txhua tus neeg uas muaj teeb meem kev rog dhau mus, tsis txhob nkim sij hawm, tab sis tig mus rau cov kws tshaj lij thiab tsis cia siab tias cov metabolism yuav zoo zuj zus yam tsis muaj tshuaj.