Berlition 300: cov lus qhia rau kev siv

nyob rau hauv ampoules ntawm cov xim av iav ntawm 12 ml, hauv daim ntawv thawv los ntawm 5, 10 lossis 20 ampoules.

nyob rau hauv blister sawb ntim ntawm 10 pcs., nyob rau hauv ib lub thawv ntawv ntawm 3, 6 lossis 10 pob.

Pharmacological kev txiav txim

Raws li coenzyme ntawm mitochondrial multienzyme complexes, nws koom nrog oxidative decarboxylation ntawm pyruvic acid thiab alpha-keto acids. Pab txo cov ntshav qabzib thiab nce glycogen hauv nplooj siab, nrog rau kov yeej cov tshuaj insulin.
Los ntawm cov kev ua haujlwm biochemical, nws yog nyob ze rau cov vitamins B. Koom nrog cov kev cai ntawm lipid thiab carbohydrate metabolism, txhawb cov metabolism hauv roj, txhim kho daim siab ua haujlwm. Kev siv trometamol ntsev ntawm thioctic acid (muaj qhov tshuaj tiv thaiv nruab nrab) hauv kev daws teeb meem rau kev tswj hwm txoj hauv kev tuaj yeem txo qhov hnyav ntawm qhov tshwm sim tsis zoo.

Cov Tshuaj Pharmacokinetics

Thaum noj ntawm qhov ncauj, nws yog sai thiab tag nrho nqus los ntawm lub plab zom mov (noj nrog zaub mov txo kev nqus). Lub sijhawm mus txog C_max - 40-60 feeb Bioavailability yog 30%. Nws muaj cov txiaj ntsig ntawm "thawj tshooj" los ntawm daim siab. Qhov tsim ntawm metabolites tshwm sim los ntawm sab saw oxidation thiab kev sib txuas. Qhov ntim ntawm kev faib tawm yog li 450 ml / kg. Lub ntsiab metabolic txoj hauv kev yog oxidation thiab sib txuas. Thioctic acid thiab nws cov metabolites yog ua kom lub raum tso tawm (80-90%). T_1/2 - 20-50 feeb Tag nrho cov ntshav Cl - 10-15 ml / min.

Sab sij huam

Kev daws rau kev txhaj tshuaj: qee lub sij hawm zoo li qhov hnyav nyob rau hauv lub taub hau thiab ua pa luv (nrog ceev rau / ntawm kev tswj hwm). Kev ua xua muaj peev xwm ua tau nyob ntawm qhov chaw txhaj tshuaj nrog cov tsos mob ntawm urticaria lossis kub hnov. Muaj qee kis, pom, ua haujlwm (dopopia), pom qhov ntshav liab hauv daim tawv thiab cov qog ua kua.
Ntsiav tshuaj Coated: hauv qee kis, kev tsis haum tshuaj ntawm daim tawv nqaij.

Kev txo qis hauv cov ntshav qab zib yog ua tau.

Tsuas tshuaj thiab tswj hwm

IvCov. Hauv kev hnyav I / O polyneuropathies, 12-24 ml (300-600 mg ntawm alpha-lipoic acid) ib hnub rau 2-4 lub lis piam. Rau qhov no, 1-2 ampoules ntawm cov tshuaj yog diluted hauv 250 ml ntawm physiological 0.9% sodium chloride tov thiab muab cov tshuaj dropwise rau kwv yees li 30 feeb. Yav tom ntej, lawv hloov mus rau kev saib xyuas kev kho mob nrog Berlition 300 hauv daim ntawv ntawm cov ntsiav tshuaj ntawm koob tshuaj ntawm 300 mg rau ib hnub.

Rau kev kho mob polyneuropathy - 1 lub rooj. 1-2 zaug ib hnub (300-600 mg ntawm alpha-lipoic acid).

Kev tiv thaiv kev nyab xeeb

Thaum kho, ib qho yuav tsum yauv tsum tsis txhob haus cawv (haus dej cawv thiab nws cov khoom ua rau lub zog ua rau tsis muaj zog).

Thaum noj cov tshuaj, koj yuav tsum tau saib xyuas cov ntshav qab zib cov ntshav kom tsis tu ncua (tshwj xeeb hauv kev pib kho. Muaj qee kis, txhawm rau txhawm rau tiv thaiv cov tsos mob ntawm tus mob ntshav qab zib tsawg, nws yuav tsum tau txo koob tshuaj insulin lossis tshuaj tiv thaiv kab mob hauv lub qhov ncauj.

Tso tawm daim ntawv thiab muaj pes tsawg leeg

Berlition yog tsim nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj coated, 30 ntsiav tshuaj rau ib pob (3 blisters ntawm 10 ntsiav tshuaj). Lwm hom kev tso tawm suav nrog gelatin tsiav tshuaj rau kev siv sab hauv, qhov mloog zoo rau kev npaj ntawm ib qho kev daws teeb meem.

Lub ntsiab nquag khoom siv yog thioctic (alpha-lipoic) acid. Ib ntsiav tshuaj muaj 300 mg ntawm thioctic acid.

Ntu cov khoom siv: microcrystalline cellulose, colloidal silicon dioxide, lactose monohydrate, croscarmellose sodium, magnesium stearate, povidone.

Cov Yuav Tsum Tau Ua

Cov kev tsis txhaum rau kev siv Berlition yog:

• cov tshuaj tiv thaiv tsis haum lossis qhov tsis haum rau alpha-lipoic acid lossis ib ntu ntawm cov tshuaj tiv thaiv,
• ua txhaum ntawm kev nqus ntawm cov piam thaj-galactose, galactosemia, lactase deficiency,
• cev xeeb tub thiab lactation,
• hnub nyoog qis dua 18 xyoo.

Tsuas tshuaj thiab tswj hwm

Cov ntsiav tshuaj Berlition noj ntawm qhov ncauj tag nrho, tsis tsoo lossis zom. Cov tshuaj yog coj ib zaug ib hnub, thaum sawv ntxov, ib nrab teev ua ntej noj tshais.

Cov kev kho mob ntev. Lub chav kawm ntawm kev kho mob yog txiav txim los ntawm tus kws kho mob tshwj xeeb, nyob ntawm qhov ntsuas thiab tus mob ntawm tus neeg mob.

Hauv kev mob ntshav qab zib polyneuropathy, alpha-lipoic acid tau muab tshuaj rau li 600 mg ib hnub twg.

Rau cov kab mob siab, qhov tshuaj txhua hnub rau cov neeg laus yog los ntawm 600 mg txog 1200 mg.

Cov lus qhia tshwj xeeb

Thaum kho nrog Berlition, cov hauv qab no yuav tsum tau coj mus rau hauv tus account:

• nyob rau hauv thawj theem pib ntawm kev kho mob hauv cov neeg mob polyneuropathy, kev ua kom zoo ntawm paresthesia yog ua tau,
• cov neeg mob ntshav qab zib thaum noj cov ntsiav tshuaj yuav tsum muaj kev soj ntsuam cov ntshav qabzib kom tsis tu ncua thiab, yog tias tsim nyog, kev kho cov tshuaj tiv thaiv kab mob,
• koj yuav tsis haus cawv thaum kho,
• tsis muaj cov ntaub ntawv qhia txog cov nyhuv ntawm alpha-lipoic acid rau ntawm tus menyuam thiab tus menyuam lub cev, yog li ntawd, cov tshuaj tsis raug txwv thaum lub sijhawm cev xeeb tub thiab pub niam mis.

Kev sib txuas lus siv yeeb tshuaj nrog kev siv thooj txhij:

• kev kho qhov mob tshwm sim ntawm cisplastine txo qis,
• cov nyhuv ntawm cov tshuaj hypoglycemic nce,
• Nrog cov khoom siv hlau, suav nrog magnesium, hlau, nrog rau calcium, alpha-lipoic acid khi rau cov sib txuas ua ke, yog li ntawd, kev siv cov kev npaj muaj nrog cov khoom no, nrog rau kev siv cov khoom siv mis nyuj, tau tso cai tsuas yog 6-8 teev tom qab noj Berlition.

Cov tshuaj ntawm cov tshuaj (nrog tib cov tshuaj muaj zog) suav nrog: Alpha Lipon, Dialipon, Thioctodar, Tiogamma, Espa-Lipon, Thioctacid BV.