Lisinopril Stada: cov lus qhia rau kev siv ntsiav tshuaj

Lisinopril yog tsim los ntawm ntau lub tuam txhab tshuaj, xws li Avant, ALSI Pharma, Severnaya Zvezda, Ozone LLC, Stada, Teva thiab lwm yam. Yog li, cov tshuaj muaj ntau lub npe siv nyob rau hauv kev lag luam kws tshuaj:

• Lisinopril Stada,
• Lisinopril Teva,
• Lisinopril SZ,
• Diroton
• Dapril thiab lwm tus.

Tag nrho cov tshuaj no ua vim lisinopril dihydrate.

Tom qab ntawd lisinopril txawv li cas ntawm lisinopril stad? Ua ntej tshaj plaws, lawv tau tsim los ntawm ntau lub tuam txhab tshuaj, nrog ntau cov txheej txheem tsim khoom. Lisinopril Stada yog tsim los ntawm Makiz-Pharma LLC (hauv Moscow) thiab Hemofarm (hauv Obninsk). Cov chaw tsim khoom lag luam no yog koom nrog lub tuam txhab Stad thiab tsim cov tshuaj raws li European qauv.

Thib ob, cov khoom lag luam muaj ntau yam zam. Piv txwv li, Alsi Pharma's Lisinopril muaj cov piam thaj mis, MCC, hmoov txhuv nplej siab, silica, talc, magnesium stearate. Kev npaj ntawm lub tuam txhab Stada, raws li cov lus qhia los ntawm cov lus qhia rau kev siv, ntxiv rau cov tshuaj uas teev saum toj no, suav nrog cov khoom xws li mannitol, ludipress (mis qab zib thiab povidone), croscarmellose sodium, calcium hydrogen phosphate.

Kev ntsuas rau siv

Cov kev qhia ntawv tso cai siv Lisinopril Stad rau:

• kub siab (ib leeg lossis nrog lwm yam tshuaj),
• lub plawv tsis ua hauj lwm (hauv kev sib txuas nrog lub plawv glycosides, diuretics),
• myocardial infarction (hauv cov neeg mob uas muaj hemodynamics ruaj khov. Siv xav tau yog thawj hnub),
• raum pathology los ntawm ntshav qab zib (cov protein tsawg hauv cov zis nrog ntshav qab zib hom 1 uas muaj qhov hnyav thiab cov neeg mob ntshav qab zib hom 2 uas muaj ntshav siab).

Muaj pes tsawg leeg, kev piav qhia, daim ntawv ntau npaum cas, pawg

Lub tuam txhab Stada tsim tawm Lisinopril nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj ntawm 5, 10 thiab 20 mg. Lawv tau ntim hauv PVC thiab ntawv ci. Lub hnab ntim thawj nyob hauv lub thawv ntawv thawv. Nws kuj muaj cov lus qhia rau kev siv. Ntawm kev muag koj tuaj yeem nrhiav pob 20 thiab 30 ntsiav tshuaj.

Cov tshuaj suav nrog lisinopril dihydrate thiab cov tshuaj pab muaj npe saud.

Cov lus qhia rau kev siv muab cov ntaub ntawv uas Lisinopril Stada yog cov ntsiav tshuaj dawb (qab zib tau), cylindrical, muaj oblique kawg nto thiab muaj kev pheej hmoo.

Cov kev qhia hais txog cov tshuaj rau pawg ACE inhibitors. Pawg tshuaj no:

• txo cov kev hloov pauv ntawm angiotensin I rau angiotensin II, uas ua rau txo qis hauv kev tso tawm ntawm aldosterone,
• thaiv qhov cuam tshuam ntawm bradykinin,
• txhim kho kev tsim ntawm prostaglandins.

Cov txheej txheem no ua rau muaj kev cuam tshuam ntawm cov renin-angiotensin-aldosterone system. Yog li no, vim tias qhov tshwm sim ntawm kev siv tshuaj, vasodilation thiab txo qis rau hauv cov ntshav siab tshwm sim.

Qhov pib ntawm cov nyhuv tshwm sim ib teev tom qab kev tswj hwm thiab kav ntev li ib hnub. Cov nyhuv ruaj khov tshwm sim tom qab 30-60 hnub ntawm kev siv Lisinopril Stad. Cov kev qhia hais ntxiv tias tsis muaj "tus mob tshem tawm" thaum tso tseg kev siv. Tsis tas li, cov tshuaj txo cov protein nyob hauv cov zis.

Siv Cov Kev Siv thiab Dosage

Cov kev qhia tau hais tias cov tshuaj Lisinopril Stada yog npaj rau kev siv qhov ncauj. Cov ntsiav tshuaj yog ntxuav nrog dej. Txais tsis xam kev noj zaub mov.

Feem ntau siv 1 ntsiav tshuaj hauv ib hnub. Cov koob tshuaj tau muab tshuaj los ntawm tus kws kho mob mus kawm nyob ntawm tus mob ntawm tus neeg mob. Cov nyiaj ntawm cov nyiaj tsim nyog tau raug xaiv kom txog rau theem xav tau ntawm cov ntshav siab mus txog. Nws tsis pom zoo kom nce cov tshuaj ntau dua li 2 hnub tom qab pib siv. Cov kev qhia qhia tau hais txog cov qauv thiab cov qauv hauv kev siv:

• nyob rau hauv rooj plaub ntawm arterial kub, qhov pib koob yog 10 mg rau ib hnub, kev saib xyuas txij nkawm yog 20 mg,
• kev siv ntau tshaj plaws ntawm 40 mg hauv ib hnub.
• Ua ntej pib kev kho mob nrog Lisinopril, koj yuav tsum tsum tsis txhob siv tshuaj diuretics rau ob peb hnub.
• yog tias nws tsis tuaj yeem thim lawv, tom qab ntawd pib siv tshuaj, raws li cov lus qhia, tsis tuaj yeem siab dua 5 mg rau ib hnub.
• Thawj cov koob tshuaj yuav tsum ua raws li kev saib xyuas neeg mob.

Nrog rau kev kub siab mob tshwm sim los ntawm txoj kev nqaim ntawm cov hlab ntsha ntawm lub raum, lawv pib nrog koob tshuaj 5 mg rau hauv kev soj ntsuam hauv tsev kho mob. Cov kev qhia ua kom saib xyuas cov ntshav siab, raum, thiab cov poov tshuaj nyob hauv cov ntshav. Cov kev saib xyuas txij nkawm nyob ntawm theem ntawm cov ntshav siab. Nws yog tus kws kho mob sau tseg.

Rau cov teeb meem lub raum, cov koob tshuaj yog xaiv tau, coj mus rau hauv tus account creatinine tshem tawm, cov tshuaj sodium thiab potassium hauv cov ntshav.

Hauv CHF, kev qhia pom zoo siv Lisinopril Stad li nram no:

• pib koob tshuaj - 2.5 mg ib hnub,
• txhawb nqa - 5-10 mg ib hnub,
• ntau kawg 20 mg ib hnub twg.

Ua ke, siv cov glycosides, cov tshuaj diuretics yog qhov tsim nyog.

Nrog ischemic necrosis ntawm lub plawv (mob plawv), Lisinopril Stada yog siv hauv tsev kho mob hauv kev kho ua ke. Tus nqi ntawm cov nyiaj raug xaiv los ntawm kws kho mob. Kev txais tos yuav pib rau thawj hnub. Siv rau hauv cov neeg mob nrog cov hemodynamics ruaj khov.

Cov lus qhia rau kev siv pom zoo siv cov txheej txheem xws li:

• thawj hnub - 5 mg,
• tom qab 1 hnub - 5 mg,
• tom qab 2 hnub - 10 mg,
• Tom qab uas - 10 mg rau ib hnub.

Txog kev mob ntshav qab zib nephropathy, Lisinopril Stada siv 10 mg ib hnub twg. Yog tias tsim nyog, nce ntxiv rau 20 mg.

Kev sib txuam

Cov lus qhia rau kev siv nco ntsoov cov kev sib cuam tshuam hauv qab no:

• nrog cov kev npaj noj ntawm poov tshuaj, potassium-sparing diuretics (Veroshpiron thiab lwm tus) thiab cyclosporine muaj kev pheej hmoo ntawm kev nce ntxiv ntawm cov poov tshuaj hauv cov ntshav,
• nrog rau lwm cov tshuaj uas txo cov ntshav siab - kev siv ua ke ua rau muaj kev nce ntxiv hauv cov nyhuv,
• nrog psychotropic thiab vasodilator - qhov txo qis hauv ntshav siab,
• nrog lithium npaj - kev nce qib hauv qib ntawm lithium hauv lub cev,
• nrog antacids - txo qis hauv kev nqus ntawm lisinopril hauv cov hnyuv,
• nrog hypoglycemic - kev qhia txiav txim siab qhov kev pheej hmoo ntawm hypoglycemia,
• nrog NSAIDs, estrogens, adrenergic agonists - txo qis hauv cov nyhuv hypotensive,
• nrog kev npaj kub - liab ntawm daim tawv nqaij, dyspeptic cuam tshuam, txo cov ntshav siab,
• nrog rau allopurinol, novocainamide, cytostatics - kev siv ua ke yuav pab txhawb kev mob leukopenia,
• nrog ethyl cawv - muaj cov nyhuv ntawm lisinopril.

Cov Yuav Tsum Tau Ua

Kev tsis haum rau lisinopril lossis lwm yam ACE inhibitors, cev xeeb tub, lactation. Keeb kwm ntawm mob hlwb thaum lub sij hawm kho nrog ACE inhibitors, kab mob siab los yog idiopathic angioedema, aortic stenosis, kab mob cerebrovascular (suav nrog cerebrovascular tsis txaus), mob plawv mob plawv, mob tsis txaus, mob hnyav ntawm lub cev tiv thaiv kab mob ntawm cov nqaij sib txuas (nrog rau , scleroderma), kev txwv tsis pub rau cov leeg pob txha hematopoiesis, mob ntshav qab zib mellitus, hyperkalemia, ob leeg lub raum leeg mob stenosis, mob ntshav tawm ntawm ib lub raum artery, mob tom qab hloov raum, lub raum tsis ua haujlwm, kev noj zaub mov noj nrog kev txwv ntawm Na +, tej yam mob nrog BCC poob qis (suav nrog raws plab, ntuav), laus laus, hnub nyoog txog 18 xyoo (kev nyab xeeb thiab kev ua tau zoo tsis tau kawm).

Yuav siv li cas: noj ntau thiab hom tshuaj kho

Sab hauv, nrog txoj hlab ntshav tawg - 5 mg ib hnub ib zaug. Thaum tsis muaj txiaj ntsig, qhov koob tshuaj tau nce ntxiv txhua 2-3 hnub los ntawm 5 mg rau qhov nruab nrab cov tshuaj kho 20-40 mg / hnub (nce qhov koob tshuaj saum toj 20 mg / hnub feem ntau tsis ua rau txo qis ntshav siab). Qhov nyiaj pab ntau tshaj txhua hnub yog 80 mg.

Nrog HF - pib nrog 2.5 mg ib zaug, tom qab ntawd koob tshuaj nce siab dua 2.5 mg tom qab 3-5 hnub.

Hauv cov neeg laus, ib qho kev tshaj tawm ntev dua hypotensive nyhuv yog feem ntau pom, uas cuam tshuam nrog kev txo qis ntawm lisinopril excretion (nws tau pom zoo kom pib kho nrog 2.5 mg / hnub).

Hauv kev mob raum tsis ua haujlwm, kev sib txuam tau tshwm sim nrog qhov txo tsawg dua lim pom tsawg dua 50 ml / min (qhov koob tshuaj yuav tsum raug txo 2 zaug, nrog CC tsawg dua 10 ml / min, qhov tshuaj yuav tsum raug txo 75%).

Nrog cov kev mob ntshav siab ntev, kev kho mob mus ntev yog qhia ntawm 10-15 mg / hnub, nrog lub plawv tsis ua haujlwm - 7,5-10 mg / hnub.

Sab sij huam

Cov lus qhia rau kev siv hais tias thaum kho mob Lisinopril Stad, qhov xwm txheej tsis txaus ntseeg tshwm sim hauv cov kabmob thiab cov kab ke hauv qab no:

• lub plawv thiab cov hlab ntshav (orthostatic hypotension, tsis tshua muaj kev nce siab hauv lub plawv, cov ntshav khiav tsis zoo hauv cov hlab ntsha ntawm lub nqaj, lub plawv nres, mob hlab ntsha tawg),
• CNS (kiv taub hau, mob taub hau, hloov pauv hloov nrawm dua, pw tsis tsaug zog, kev nyuaj siab),
• kev ua pa ntawm lub cev (hnoos qhuav, los ntswg, hnoos qeev yog tsis tshua muaj),
• kev mob plab zom mov (dyspepsia, gastralgia, qog ua pa qhuav, mob caj pas, kab mob siab, mob siab tsis tshua muaj tshwm sim),
• cov kab mob zis (feem ntau muaj qhov ua tsis taus ntawm lub raum ua haujlwm),
• daim tawv nqaij (khaus, tawm pob, ua pob liab vog, mob psoriasis, tawm hws ntau dhau, thiab lwm yam),
• kev ua xua nyob rau hauv daim ntawv ntawm urticaria, Quincke's edema, erythema, ua npaws thiab lwm yam kev qhia.

Tsis tshua muaj muaj kev nce ntxiv ntawm urea, creatinine, poov tshuaj nyob rau hauv cov ntshav.

Qee zaum tom qab siv tas yuav muaj kev nkees ntau dua, muaj ntshav qab zib tsawg.

Cov kev qhia faib txhua yam tsis zoo tshwm sim los ntawm cov tshuaj lisinopril rau hauv ntau zaus, tsis tshua muaj thiab tsis tshua muaj tshwm sim.

Thaum muaj qhov noj ntau dhau, muaj qhov ua kom lub cev tsis tshua muaj siab, hnoos, hnoos qeev qhuav, kiv taub hau, txob taus, nkees, nquag ua pa, palpitations lossis, ntawm qhov tsis txaus, nws txo qis, tsis txaus siab ntawm cov dej thiab electrolytes hauv cov ntshav, lub raum tsis ua haujlwm, oliguria. Nrog rau cov tshwm sim no, kev qhia tau qhia txog kev siv tshuaj kho mob.

Pharmacological kev txiav txim

ACE inhibitor, txo qhov tsim ntawm angiotensin II los ntawm angiotensin I. Txo cov ntsiab lus ntawm angiotensin II ua rau txo qis ncaj qha rau kev tso tawm ntawm aldosterone. Txo txo ​​cov kev ua haujlwm ntawm bradykinin thiab nce kev tsim kho ntawm Pg. Nws txo OPSS, ntshav siab, preload, siab nyob rau hauv cov hlab ntsws capillaries, ua rau muaj kev nce siab hauv IOC thiab nce myocardial zam rau kev ntxhov siab hauv cov neeg mob plawv tsis ua haujlwm. Nthuav cov hlab ntsha kom ntau dua li cov leeg ntshav. Qee qhov cuam tshuam tau piav qhia los ntawm cov nyhuv rau cov ntaub so ntswg-angiotensin. Nrog rau siv ntev, hypertrophy ntawm myocardium thiab phab ntsa ntawm cov hlab ntsha ntawm hom tiv thaiv poob qis. Txhim kho cov ntshav xa mus rau ischemic myocardium.

ACE inhibitors lengthen lub neej cia siab rau cov neeg mob plawv tsis ua hauj lwm, qeeb kev loj hlob ntawm LV tsis ua haujlwm hauv cov neeg mob tom qab myocardial infarction yam tsis muaj kev soj ntsuam tshwm sim ntawm lub plawv nres.

Qhov pib ntawm kev ua yog tom qab 1 teev. Qhov siab tshaj plaws txiav txim siab tau txiav txim siab tom qab 6-7 teev, lub sijhawm yog 24 teev. Nrog rau kev kub siab, pom cov nyhuv hauv thawj hnub tom qab pib kho, qhov ua haujlwm ruaj khov tshwm sim tom qab 1-2 lub hlis.

Kev Sib Sau thiab daim ntawv ntawm kev tso tawm

Ib qho ntsiav tshuaj suav nrog 5 mg, 10 mg thiab 20 mg ntawm lub ntsiab feem, uas sawv cev los ntawm lisinopril dihydrate. Kuj muaj:

• MCC
• Mannitol
• Povidone
• Mis qab zib
• Stearic Acid Magnesium
• Khoom siv calcium phosphate
• Croscarmellose sodium
• Colloidal silicon dioxide.

Cov tshuaj ntawm lub teeb qab zib ntxoov ntxoo ntawm cov duab cylindrical yog muab tso rau hauv lub hlwv. ntim ntawm 10 Sab hauv pob ntawv muaj 2 lossis 3 blist. ntim.

Kho thaj chaw

Nyob rau hauv kev cuam tshuam ntawm ACE inhibitor, qhov kev txo qis ntawm kev tsim cov tshuaj angiotensin 1 thiab 2 raug pom. Nrog rau qhov txo qis ntawm angiotensin 2, qhov txo qis hauv kev tso tawm ntawm aldosterone yog kaw. Nrog rau qhov no, qhov tsis zoo ntawm bradykinin tsawg zuj zus, kev tsim khoom ntawm prostaglandins nce. Cov tshuaj pab cuam rau hauv kev txwv tsis pub cov renin-angiotensin-aldosterone system. Raws li qhov no, qhov txo qis hauv cov ntshav siab thiab preload raug pom, kev tiv thaiv peripheral vascular tsis kam thiab siab sab hauv cov hlab ntsha txo qis, thiab hauv cov neeg tsis tuaj yeem ua haujlwm ntawm CVS, myocardial kam rau ua rau cov khoom thauj nce ntxiv. Qhov ua tau zoo ntawm lisinopril tshwm sim los ntawm kev nthuav dav ntawm cov hlab ntsha.

Cov nyhuv antihypertensive tshwm sim 1 teev tom qab noj tshuaj, qhov ntshav siab tshaj plaws ntawm cov tshuaj nquag tau nce mus txog hauv 7 teev thiab hnub tom qab yog cai. Nrog cov ntshav siab nce ntxiv, qhov ua kom zoo ntawm cov tshuaj tau sau rau thawj hnub ntawm kev kho tshuaj kho, cov nyhuv ruaj khov yog ua tiav nyob hauv 1-2 hlis. Nyob rau hauv kev sib tham ntawm kev ua tiav sai ntawm cov ntsiav tshuaj tswj hwm, cim tias kub siab tsis pom.

Tshuaj yuav pab txo kom qhov tsis pom muaj protein ntxiv hauv cov zis. Hauv cov tib neeg muaj cov cim qhia ntawm hyperglycemia, rov qab ua haujlwm ntawm kev ua haujlwm ntawm qhov raug mob glomerular endothelium tau sau tseg.

Nrog lub sijhawm ncua ntev ntawm Lisinopril Stad ntsiav tshuaj, hypertrophic hloov hauv myocardium, nrog rau kev kho kab mob rau hauv CVS, kev coj ua haujlwm ntawm cov endothelium nrog rau cov ntshav muab rau myocardium tuaj yeem pom.

Nws tsim nyog pom tias ACE inhibitors nce lub neej nyob hauv cov neeg muaj mob ntev ntawm lub plawv tsis ua hauj lwm, thiab qhov kev vam meej ntawm sab laug ventricular kawg nyob hauv cov neeg uas tau raug mob myocardial infarction yam tsis muaj cov cim ntawm lub plawv tsis ua hauj lwm.

Kev nqus ntawm gastrointestinal mucosa yog pom ntawm 30%. Thaum noj mov, tsis muaj ib qho poob hauv qhov nqus ntawm cov tshuaj. Qhov qhia txog kev ntsuas ntawm tus ciam yog 25-30%.

Cov kev sib raug zoo ntawm lisinopril nrog cov plasma protein yog tau sau tseg 5%. Cov khoom ua kom nquag plias ntawm cov ntsiav tshuaj tsis mus los ntawm cov txheej txheem ntawm biotransformation hauv lub cev. Kev nthuav tawm ntawm lisinopril hauv nws cov qauv qub yog nqa los ntawm cov hlaus. Ib nrab-lub neej nyob yog txog 12 teev. Kev zeem cia ntawm cov tshuaj yog kaw nrog cov cim loj ntawm lub raum tsis ua haujlwm.

Lisinopril Stada: cov lus qhia ua tiav rau kev siv

Nqe: ntawm 85 txog 205 rubles.

Lisinopril Stada Tshuaj siv yog npaj rau kev siv ncauj.

Thaum muaj ntshav siab, lawv tau raug hais kom haus 5 mg ntawm cov tshuaj ib hnub ib zaug. Thaum tsis tau hais tawm los ntawm kev siv tshuaj, nws muaj peev xwm nce qhov ntau ntxiv los ntawm 5 mg (txhua 2-3 hnub) kom txog rau thaum nruab nrab cov tshuaj kho txhua hnub ntawm 20-40 mg tau mus txog. Thaum lub sij hawm kho kev kho mob, ib koob tshuaj txhua hnub ntawm 20 mg yog sau tseg. Nws yuav tsum raug sau tseg tias qhov siab tshaj plaws ntawm cov tshuaj ib hnub yuav tsum tsis pub tshaj 40 mg.

Kev kho mob nyhuv tau zoo tom qab 2-4 lub lis piam. txij lub sijhawm pib ntawm txoj kev kho, qhov no yuav tsum raug coj los txiav txim thaum nce ntxiv ntawm cov tshuaj. Nrog rau qhov mob nyhav me ntsis ntawm cov tshuaj ua kom haum, ib qho ntxiv ntxiv ntawm lwm cov tshuaj tiv thaiv kabmob tuaj yeem kho tau.

Sab sij huam

Los ntawm CCC: txo qis ntshav siab, arrhythmias, mob hauv siab, tsis tshua - orthostatic hypotension, tachycardia.

Los ntawm cov hlab ntsha hauv lub cev: kiv taub hau, mob taub hau, qaug zog, tsaug zog, duav ntawm cov leeg ntawm nqaj thiab daim di ncauj, tsis tshua muaj - asthenia, lability ntawm mus ob peb vas, tsis meej pem.

Los ntawm lub plab zom mov: xeev siab, ua tsis taus pa, tsis qab los, hloov pauv, mob plab, mob plab zom mov, qhov ncauj qhuav.

Hematopoietic plab hnyuv siab raum: leukopenia, thrombocytopenia, neutropenia, agranulocytosis, ntshav liab (qis Hb, erythrocytopenia).

Ua xua: angioedema, tawv nqaij sawv pob, khaus.

Qhov kuaj pom: hyperkalemia, hyperuricemia, tsis tshua muaj - nce kev ua haujlwm ntawm "daim siab" hloov ntshav, hyperbilirubinemia.

Lwm yam: "qhuav" hnoos, txo qis potency, tsis tshua muaj - mob raum tsis ua haujlwm, mob pob qij txha, mob pob txha, ua npaws, edema (tus nplaig, daim di ncauj, nqaj), qhov tsis zoo ntawm lub raum ntawm tus me nyuam hauv plab.

Cov lus qhia tshwj xeeb

Kev saib xyuas tshwj xeeb yog yuav tsum tau ua thaum muab tshuaj rau cov neeg mob uas muaj ob lub raum mob ntshav siab ntawm lub raum los yog stenosis ntawm ib lub raum leeg ntshav (tej zaum kev nce ntawm urea thiab creatinine nyob rau hauv cov ntshav), cov neeg mob ua mob rau cov hlab ntshav hlab plawv lossis kab mob cerebrovascular, nrog decompensated lub plawv tsis ua hauj lwm (mob hypotension, myocardial infarction, stroke). Hauv cov neeg mob uas lub plawv tsis ua hauj lwm, txoj hlab ntshav hauv txoj hlab ntshav tuaj yeem ua rau lub raum khiav tsis zoo.

Thaum siv cov tshuaj uas txo cov ntshav siab hauv cov neeg mob nrog kev phais mob ntau lossis thaum lub sijhawm tso tshuaj loog, lisinopril tuaj yeem thaiv kev tsim cov tshuaj angiotensin II, theem nrab kom them nyiaj rov qab muaj kev paub meej.

Kev nyab xeeb thiab ua haujlwm ntawm lisinopril hauv menyuam yaus tseem tsis tau teeb tsa.

Ua ntej pib kev kho mob, nws yog qhov tsim nyog kom them nyiaj rau qhov poob ntawm cov kua dej thiab cov ntsev.

Siv thaum cev xeeb tub yog contraindicated, tshwj tsis yog nws tsis tuaj yeem siv lwm yam tshuaj lossis lawv tsis muaj txiaj ntsig (tus neeg mob yuav tsum tau txais kev ceeb toom txog kev pheej hmoo rau tus menyuam hauv plab).

Cov lus nug, lus teb, tshuaj xyuas ntawm cov tshuaj Lisinopril Stada

Cov ntaub ntawv muab yog npaj rau kev kho mob thiab kws tshaj lij. Cov ntaub ntawv muaj tseeb tshaj plaws txog cov tshuaj muaj nyob hauv cov lus qhia uas txuas nrog lub ntim los ntawm cov kws tsim khoom lag luam. Tsis muaj cov ntaub ntawv tso tawm rau ntawm no lossis lwm nplooj ntawv ntawm peb lub xaib tuaj yeem hloov chaw rau qhov tsis txaus siab tus kheej rau tus kws tshaj lij.

Tus neeg mob tshuaj xyuas txog kev siv tshuaj

Kev ntsuas qhov pom ntawm cov tswvyim siv Lisinopril Stada tau ua tiav. Kev txheeb xyuas pom muaj ob qho tib si zoo thiab tsis zoo.

Ntawm cov "pluses", cov neeg mob sau tseg:

• efficiency
• txoj kev yooj yim kom tau txais
• Tus nqi zoo rau nyiaj.

"Cons" tau qhia raws li hauv qab no:

• muaj cov kev mob tshwm sim (ntawm qhov qhia hauv cov lus qhia rau kev siv, hnoos, raws plab, kub siab, xeev siab, mob taub hau yog tshwm sim),
• cov nyhuv tsis tuaj tam sim ntawd
• qhov tsim nyog diuretic tshem tawm ua ntej kev kho mob,
• txaus ntshai rau tus neeg laus tom qab 65 xyoo, raws li cov lus qhia.

Cov kws kho mob tshuaj xyuas

Xav txog cov lus pom ntawm cov kws paub meej txog cov tshuaj Lisinopril Stada. Kev tshuaj xyuas ntawm cov kws kho mob tau tshaj tawm tias cov tshuaj muaj txiaj ntsig, feem ntau zoo siab rau los ntawm cov neeg mob.

Tib lub sijhawm, cov kws kho mob sau tseg tias Lisinopril Stada tsis yog ib txwm daws nws tus kheej, nws yog qhov yuav tsum tau siv txoj kev kho mob nyuaj. Nws yog qhov nyuaj los soj ntsuam cov mob ntawm ob lub raum, uas yog, txhawm rau ntsuas qib ntawm creatinine.

Cov nyhuv ntawm cov tshuaj Lisinopril Stada

Cov tshuaj tiv thaiv kab mob, los yog lwm txoj hauv kev thaiv, tus "suppressor" ntawm ACE tiv thaiv kev tsim cov tshuaj hormone angiotensin, uas ua rau vasoconstriction thiab, vim li ntawd, nce siab. Ntxiv rau, angiotensin ua rau lub cev aldosterone, uas txwv tsis pub cov kua hauv lub cev tawm. Nquag, nws pab txhawm rau txhim kho ntshav thiab nce ntshav siab, tab sis qee zaus nws tsis muaj qhov tsis zoo txaus ntseeg hauv daim duab edema, ntau dhau ntawm lub siab thiab lub plawv tsis ua haujlwm.

Tag nrho cov no tuaj yeem zam dhau los ntawm kev tsub tawm kev tsim cov tshuaj angiotensin ntau heev nyob rau lub sijhawm, uas yog lisinopril ua li cas. Nws lub zog ua rau nthuav tawm ntawm cov hlab ntsha loj rau ntau dua li cov leeg ntawm cov leeg. Qhov no yuav tsum tau txiav txim siab thaum sib txuas lisinopril nrog lwm cov tshuaj.

Txawm hais tias koj dheev tsum tsis noj tshuaj ntxiv, cov nyhuv yuav nyob rau qee lub sijhawm: yuav tsis muaj qhov dhia dhia ceev ceev hauv siab. Nrog kev siv ntev, lisinopril pab kho cov nqaij myocardial cuam tshuam los ntawm ischemia.

Rau cov neeg uas tau raug kev txom nyem myocardial infarction yam tsis muaj cov tsos mob hnyav, qhov no txhais tau hais tias maj mam ua kom tiav ntawm cov leeg ntshav tawm mus. Thiab rau cov neeg nyob nrog lub plawv tsis ua haujlwm ntev, qhov no yog ib txoj hauv kev los txuas lawv txoj kev ua neej.

Noj ntau dhau

Yog tias koj tshaj koob tshuaj, cov tsos mob hauv qab no tshwm sim:

• siab txo hauv qab 90/60,
• qhuav qog ua pa tawm, hnoos,
• ceeb, ntxhov siab, chim siab, los sis hloov ua ntej - tsaug zog heev,
• lub raum khiav tsis zoo, tso zis kom rov zoo.

Yog tias kev noj qab haus huv tshaj plaws paub tseeb, ua ntej ntawm txhua yam koj yuav tsum tau tshem ntawm cov seem ntawm cov tshuaj uas tau nkag mus rau hauv lub cev: yaug lub plab thiab noj tshuaj. Tom qab ntawd, yog tias tsim nyog, nws tsim nyog los txo cov nyhuv ntawm lisinopril: hauv qhov xwm txheej tsis sib haum, nws txaus los pab tus neeg mob coj txoj hauj lwm tav toj thiab tsa nws ob txhais ceg. Yog tias tau siv ntau yam tshuaj, vasoconstrictor tshuaj thiab muaj cov tshuaj sodium chloride yuav tsum ua.

Yog tias cov tshuaj hauv qhov ntau dhau heev lawm tau nkag mus rau hauv cov ntshav, hemodialysis yog kev kho mob.

Sib piv nrog lwm cov tshuaj thiab dej caw

Lisinopril tuaj yeem siv ua ke nrog calcium channel blockers thiab adrenergic blockers, tab sis nws yuav tsum tau yug los hauv lub siab tias cov nyhuv ntawm cov tshuaj muaj zog tuaj.

Nws yog qhov zoo dua rau kev tso tseg kev nqus tshuaj ntawm diuretics lossis, kom deb li sai tau, txo lawv cov tshuaj. Poov tshuaj-sparing tshuaj thaum noj yuav ua rau hyperkalemia.

Lizonopril Stada yuav tsum tsis txhob muab sib xyaw nrog barbiturates, tshuaj tiv thaiv kev tawm tsam thiab kev tiv thaiv kev kub ntxhov - lub siab yuav poob qis thiab loj.

Kev noj tshuaj rau mob rau mob txhab thiab mob caj dab yuav cuam tshuam nrog kev nqus ntawm lisinopril.

Kev siv cov lisinopril nrog insulin thiab hypoglycemic cov neeg sawv cev ua rau lub ntsej muag hypoglycemia, tshwj xeeb tshaj yog thaum thawj lub hli ntawm chav kawm ntawm lisinopril.

Nonsteroidal anti-inflammatory tshuaj txo cov nyhuv ntawm cov tshuaj.

Koj tsis tuaj yeem ua ke cov tshuaj nrog cytostatics, allopurinol thiab procainamide kom tsis txhob muaj kev txhim kho ntawm leukopenia.

Txee lub neej thiab chaw cia khoom

Cov tshuaj muaj peev xwm tswj tau nws lub zog rau peb lub xyoos, muab tag nrho lub sijhawm no nws khaws cia hauv qhov chaw tsaus, ntawm qhov kub tsis tshaj 25 degrees.

Cov tshuaj yuav tsum tsis txhob cia nyob hauv ib qho chaw uas menyuam yaus tuaj yeem pom nws, thiab coj tom qab hnub tas sijhawm.

Tus nqi ntawm cov tshuaj nyob ntawm qhov ntau npaum li cas ntawm cov tshuaj thiab thaj av uas nws muag. Tus nqi ntawm kev ntim, nyob rau hauv uas 30 ntsiav tshuaj nrog tshuaj ntawm 5 mg, yog li 110 rubles. Txog tus nqi sib xws li 20 ntsiav tshuaj nrog kev noj tshuaj ntawm 10 mg. Ib pob nrog 20 ntsiav tshuaj ntawm 20 mg nqi txog 170 rubles.

Muaj ntau ntau yam tshuaj nrog tib cov tshuaj yeeb dej caw uas sib txawv hauv cov khoom siv sib txawv thiab hauv cov teb chaws tsim. Yog tias koj xav tau ACE inhibitor ntawm lwm pab pawg, koj yuav tsum kawm cov tshuaj raws li captopril, zofenopril, benazepril thiab fosinopril.

Yog tias koj xav tau cov tshuaj kom txo qis siab los ntawm lwm pab pawg, koj tuaj yeem them mloog rau calcium channel blockers (verapamil, diltiazem) lossis antispasmodics (drotaverine thiab tshuaj raws nws).

Lizonopril Stada - cov tshuaj noj kom txo qis siab thiab txhim kho cov ntshav ncig hauv cov leeg nqaij hauv lub siab. Ua ntej koj pib noj cov tshuaj, koj yuav tsum paub tseeb tias tsis muaj contraindications thiab sab laj nrog kws kho mob.

Kev taw qhia ntawm cov tshuaj Lisinopril Stada

Arterial hypertension, mob plawv tsis ua haujlwm (raws li kev kaw qhov tsis txaus poov tshuaj-txo cov diuretics lossis, yog tias tsim nyog, ua ke nrog digitalis npaj), mob myocardial infarction nrog cov hlab plawv ruaj (rau cov neeg mob uas muaj ntshav tsis txaus nrog ntshav siab dua 100 hli Hg. Art., Ntshiab creatinine qib qis dua 177 μmol / L (2 mg / dL) thiab proteinuria tsawg dua 500 mg / hnub) ntxiv rau cov qauv kev kho mob ntawm myocardial infarction, dua li hauv ua ke nrog nitrates.

Cev xeeb tub thiab lactation

Siv thaum cev xeeb tub yog contraindicated. Ua ntej pib kev kho mob, cov poj niam ntawm lub hnub nyoog yug menyuam yuav tsum ua kom ntseeg tau tias lawv tsis tau muaj menyuam. Thaum kho, cov poj niam yuav tsum muaj kev tiv thaiv kom tsis txhob muaj menyuam. Yog tias cev xeeb tub tseem tshwm sim thaum kho, nws yog ib qho tsim nyog, raws li tus kws kho mob pom zoo, kom hloov cov tshuaj nrog lwm tus, tsis tshua muaj kev phom sij rau tus menyuam, txij li thaum siv Lisinopril Stada ntsiav tshuaj, tshwj xeeb tshaj yog 6 lub hlis dhau los ntawm kev xeeb menyuam, tuaj yeem cuam tshuam tus menyuam hauv plab.

ACE cov tshuaj tiv thaiv tuaj yeem tawm hauv cov kua mis. Cov txiaj ntsig ntawm kev pub mis niam rau menyuam yaus tseem tsis tau kawm. Yog li ntawd, lub sijhawm kho yuav tsum tsis pub mis niam.

Tsuas tshuaj thiab tswj hwm

Sab hauv raws li txoj cai, ib zaug thaum sawv ntxov, tsis hais txog ntawm qhov khoom noj, nrog qhov muaj kua ntau txaus (piv txwv li, ib khob dej).

Arterial hypertension: thaum pib koob - 5 mg / hnub, thaum sawv ntxov. Kev xaiv tshuaj yog nqa tawm kom ua tiav cov ntshav siab rau cov ntshav siab. Tsis txhob nce qhov ntau ntawm cov tshuaj ntxov dua li 3 lub lis piam tom qab. Feem ntau, koob tshuaj saib xyuas yog 10-20 mg ib hnub ib zaug. Tso cai nyob rau hauv ib koob - 40 mg 1 zaug nyob rau ib hnub.

Nrog lub raum tsis ua haujlwm, lub plawv tsis ua haujlwm, tsis txaus siab rau diuretic tshem tawm, hypovolemia thiab / lossis ntsev ntsev (piv txwv li, los ntawm ntuav, raws plab lossis kho diuretic), mob hnyav lossis kho kom rov qab kho ntshav siab, nrog rau cov neeg laus laus, tsawg koob tshuaj 2.5 mg 1 lub sijhawm yuav tsum tau ua ib hnub nyob rau thaum sawv ntxov.

Lub plawv tsis ua hauj lwm (tej zaum yuav siv ua ke nrog tshuaj diuretics thiab digitalis npaj): thawj qhov hno - 2.5 mg ib hnub ib zaug thaum sawv ntxov. Cov koob tshuaj txij nkawm yog xaiv nyob rau hauv cov theem, nce qhov koob tshuaj los ntawm 2.5 mg. Cov koob tshuaj tau nce qeeb qeeb, nyob ntawm tus neeg teb ntawm tus neeg mob. Lub sijhawm nruab nrab ntawm qhov nce ntxiv yuav tsum yog tsawg kawg 2, nyiam dua 4 lub lis piam. Qhov siab tshaj plaws yog 35 mg.

Mob myocardial infarction nrog cov hemodynamic ruaj khov (yuav tsum yog cov tshuaj ntxiv rau nitrates siv, piv txwv, iv lossis hauv daim ntawv ntawm daim tawv nqaij thiab ntxiv rau qhov kev kho mob ib txwm muaj myocardial infarction): lisinopril yuav tsum pib ua ntej 24 teev tom qab thawj cov tsos mob raug rau hemodynamic tsis muaj zog ntawm tus neeg mob. Thawj koob tshuaj yog 5 mg, tom qab ntawd lwm 5 mg tom qab 24 teev thiab 10 mg tom qab 48 teev, tom qab ntawd ntawm koob tshuaj 10 mg / hnub. Nrog rau CAD qis (mmHg), nyob rau theem pib ntawm txoj kev kho lossis thawj 3 hnub tom qab lub plawv nres, txo koob tshuaj 2.5 mg yuav tsum raug kho.

Yog tias muaj cov hlab ntsha hypotension (SBP qis dua 100 mmHg), qhov kev saib xyuas txhua hnub yuav tsum tsis pub tshaj 5 mg thiab, yog tias tsim nyog, yuav tsum txo qis txog 2.5 mg. Yog tias, txawm hais tias qhov txo qis rau hauv ib hnub rau 2.5 mg, kho cov roj ntsha hypotension (SBP qis dua 90 hli Hg rau ntau dua 1 teev) tseem muaj, lisinopril yuav tsum tsis ua mus ntxiv.

Lub sijhawm tiv thaiv kev kho yog 6 lub lis piam. Qhov tsawg kawg nkaus txij nkawm txhua hnub koob tshuaj yog 5 mg. Nrog rau cov tsos mob ntawm lub plawv tsis ua haujlwm, lisinopril kho tsis tau tso tseg.

Lisinopril yog sib haum nrog concomitant iv lossis txiav tawm (thaj ua rau thaj) thaj chaw tswj hwm ntawm nitroglycerin.

Dosage nrog kev txo qis hauv lub raum kev ua haujlwm (Cl creatinine 30-70 ml / min) thiab rau cov neeg laus (laus dua 65 xyoos): thawj qhov hno - 2.5 mg / hnub, thaum sawv ntxov, kev saib xyuas txij nkawm (nyob ntawm qhov muaj txiaj ntsig ntawm ntshav siab) - 5– 10 mg / hnub. Qhov siab tshaj plaws rau kev noj tshuaj txhua hnub yuav tsum tsis pub tshaj 20 mg.

Txhawm rau pab txhawb rau cov tib neeg xaiv cov koob tshuaj, cov ntsiav tshuaj ntawm Lisinopril Stada 2.5, 5, 10 thiab 20 mg muaj qhov sib cais tsis sib luag (rau qhov yooj yim ntawm faib cov ntsiav tshuaj ua 2 lossis 4 qhov sib luag).

Lub sijhawm kho yog txiav txim los ntawm tus kws khomob tuaj koom.

Tso tawm daim ntawv, muaj pes tsawg leeg thiab ntim khoom

Lub plawv tshuaj Lizinopril Stada, uas peb lub tsev muag tshuaj muab rau yuav, muaj nyob rau hauv daim ntawv dawb lub plhaub-dawb cov ntsiav tshuaj ntim hauv cov hlwv yas, kaum hauv txhua. Cov hlwv ntim tau ntim rau hauv pob ntawv los ntawm daim ntawv pleev xim, uas lub npe ntawm cov tshuaj raug luam tawm, hnub tsim tawm, cov ntaub ntawv hais txog qhov chaw tsim khoom, thiab lwm cov ntaub ntawv tseem ceeb tau qhia. Txhua pob ntawv kuj muaj cov lus qhia rau kev siv tshuaj yeeb tshuaj Lisinopril Stada, nws muaj nws cov lus qhia ntxaws ntxaws. Tus nqi ntawm cov tshuaj Lisinopril Stada nyob ntawm tus naj npawb ntawm cov ntsiav tshuaj hauv pob - lawv tuaj yeem yog 10, 20, lossis 30. Tsis tas li ntawd, qhov kev cia siab hauv ib ntsiav tshuaj ntawm cov tshuaj nquag, lisinopril, kuj yuav txawv. Nws tuaj yeem yog 5, 10 thiab 20 mg, ntsig txog. Ntawm peb lub vev xaib koj tuaj yeem qhia meej qhov muaj ib daim ntawv lossis lwm hom tshuaj, npaj kev xa mus tsev, thiab nyeem cov tshuaj xyuas ntawm Lisinopril Stada sab laug los ntawm cov neeg uas tau siv cov tshuaj no rau kev kho mob. Ntxiv nrog rau lisinopril, cov tshuaj ntawm cov tshuaj no muaj cov neeg hauv qab no: • Rau-atom cawv-aldite, • Microcrystalline cellulose, • Lactose, • Disubstituted calcium phosphate, • ntsev ntawm magnesium thiab stearic acid, • Lwm yam kev zam. Cov ntawv qhia tag nrho thiab qhov loj seem ntawm cov excipients tuaj yeem nrhiav tau los ntawm kev kawm qhov kev piav qhia ntawm cov tshuaj muaj nyob hauv cov lus qhia raug cai.

Kev tiv thaiv kev nyab xeeb

Kev kho mob nrog lisinopril rau kev mob plawv ntev yuav tsum pib hauv tsev kho mob nrog kev sib txuas nrog kev kho mob nrog diuretics lossis diuretics hauv kev txhaj tshuaj ntau (piv txwv li, ntau dua 80 mg ntawm furosemide), tsis muaj dej txaus los yog ntsev (hypovolemia lossis hyponatremia: ntshav dej sodium tsawg dua 130 mmol / l), ntshav siab tsawg , lub plawv tsis ua hauj lwm tsis ruaj khov, txo lub raum kev ua haujlwm, kev kho mob siab dua ntawm vasodilators, tus neeg mob laus dua 70 xyoo.

Cov tshuaj electrolytes thiab cov creatinine nyob rau hauv cov ntshav cov ntshav thiab cov ntsuas ntawm cov ntshav yuav tsum tau saib xyuas, tshwj xeeb tshaj yog thaum pib kho thiab hauv cov pab pawg muaj kev pheej hmoo (cov neeg mob raum tsis ua haujlwm, kab mob tiv thaiv kab mob), nrog rau kev siv immunosuppressants, cytostatics, allopurinol thiab procainamide.

Arterial hypotension. Cov tshuaj yuav ua rau txo qis ntshav siab, tshwj xeeb yog tom qab siv tshuaj thawj zaug. Cov tsos mob arterial hypotension hauv cov neeg mob ntshav siab uas tsis muaj teeb meem yog qhov tsis tshua muaj tshwm sim. Ntau zaus, cov tsos mob ntawm txoj hlab ntsha o tuaj yeem tshwm sim hauv cov neeg mob ntshav lossis ntshav tsis txaus, tau txais diuretics, ua raws li cov zaub mov muaj ntsev tsawg, tom qab ntuav lossis zawv plab, lossis tom qab mob hemodialysis. Cov tsos mob arterial hypotension feem ntau tau sau tseg feem ntau hauv cov neeg mob uas mob plawv tsis ua haujlwm nrog lub raum tsis ua haujlwm lossis tsis muaj nws, thiab ntxiv rau cov neeg mob tau txais cov koob tshuaj ntawm lub voj diuretics raug mob los ntawm hyponatremia lossis lub raum tsis ua haujlwm. Hauv cov neeg mob li no, txoj kev kho yuav tsum pib ua raws li kev saib xyuas kho mob nruj, zoo dua hauv tsev kho mob, noj tsawg thiab qhov tshuaj yuav tsum hloov nrog ceev faj. Nyob rau tib lub sijhawm, kev saib xyuas lub raum kev ua haujlwm thiab ntshav ntau ntxiv yog tsim nyog. Yog tias tsim nyog, tsum tsis ua kev kho mob nrog diuretics.

Ceev faj kuj tseem tsim nyog rau cov neeg mob uas mob angina pectoris lossis kab mob cerebrovascular, uas kev txo ntshav siab ntau dhau los tuaj yeem ua rau myocardial infarction lossis mob stroke.

Kev pheej hmoo ntawm kev mob tshwm sim ntawm txoj hlab ntshav liab thaum lub sijhawm lisinopril txoj kev kho tuaj yeem txo los ntawm kev thim cov diuretic ua ntej kev kho mob nrog lisinopril.

Thaum muaj kev cuam tshuam ntawm cov hlab ntsha hypotension, tus neeg mob yuav tsum tau pw, muab dej haus los yog txhaj tshuaj rau lub cev (kom them nyiaj rau qhov ntim ntawm qhov dej). Atropine tuaj yeem xav kho kho concomitant bradycardia. Tom qab qhov ua tiav ntawm txoj kev txo qis ntawm txoj hlab ntaws los ntawm kev noj thawj koob tshuaj, tsis tas yuav tsum tso tseg qhov kev ceev faj ntxiv tom qab koob tshuaj. Yog hais tias arterial hypotension nyob rau hauv tus neeg mob nrog lub plawv tsis ua hauj lwm muaj zog, yuav txo qhov koob tshuaj thiab / lossis tshem tawm ntawm diuretic thiab / lossis lisinopril yuav tsum tau ua. Yog tias ua tau, 2-3 hnub ua ntej pib kev kho mob nrog lisinopril, kev kho mob nrog diuretics yuav tsum tsis ua mus ntxiv.

Arterial hypotension hauv kev mob siab myocardial infarction. Hauv kev mob myocardial infarction, lisinopril txoj kev kho tsis tuaj yeem pib yog tias, kev saib xyuas kev kho mob yav dhau los nrog cov tshuaj vasodilator, muaj kev pheej hmoo ntxiv rau lub cev tsis zoo ntawm hemodynamic tsis tau. Qhov no siv rau cov neeg mob CAD ntawm 100 hli RT. Kos duab. thiab hauv qab los yog nrog kev poob siab cardiogenic. Nrog CAD ntawm 100 hli RT. Kos duab. thiab hauv qab no, qhov kev saib xyuas txij nkawm yuav tsum raug txo kom 5 mg lossis txog 2.5 mg. Hauv kev mob myocardial infarction, noj cov lisinopril tuaj yeem ua rau mob ntshav liab ntau heev. Nrog ruaj khov ntawm cov roj ntsha hypotension (SBP tsawg dua 90 hli Hg.rau ntau tshaj 1 h) kev kho mob lisinopril yuav tsum tsis ua mus ntxiv.

Cov neeg mob uas muaj lub plawv tsis ua haujlwm ntev tom qab cov mob myocardial infarction, lisinopril yuav tsum tau kho tsuas yog nrog cov ntshav tsis ruaj khov.

Renovascular hypertension / raum artery stenosis (saib "Contraindications"). Nrog kev kho mob ntshav siab thiab ob sab sib luag (lossis tsis muaj ob lub raum nrog ib lub raum) lub raum artery stenosis, kev siv lisinopril cuam tshuam nrog kev pheej hmoo ntawm kev txo qis hauv cov ntshav siab thiab lub raum tsis ua haujlwm. Qhov kev pheej hmoo no yuav ua rau siab zog los ntawm kev siv tshuaj diuretics. Txawm hais tias nyob rau hauv cov neeg mob uas muaj kev kho lub raum artery stenosis, lub raum tsis ua hauj lwm tuaj yeem nrog los ntawm kev hloov pauv me ntsis hauv cov ntshav creatinine. Yog li, kev kho mob ntawm cov neeg mob zoo li no yuav tsum tau nqa tawm hauv tsev kho mob los ntawm kev saib xyuas kev noj qab haus huv, pib nrog kev txhaj tshuaj tsawg, thiab cov koob tshuaj yuav tsum nce zuj zus thiab ceev faj. Hauv thawj lub lim tiam ntawm kev kho, kev kho mob diuretic yuav tsum muaj kev cuam tshuam thiab lub raum kev ua haujlwm.

Lub raum khiav tsis zoo. Siv nrog ceev faj hauv cov neeg mob uas lub raum tsis ua haujlwm. Cov neeg mob no yuav tsum tau txhaj tshuaj qis dua lossis ncua sijhawm ntev dua ntawm cov koob tshuaj (saib "Dosage and Administration").

Cov ntawv ceeb toom ntawm kev sib raug zoo ntawm lisinopril kev kho mob thiab lub raum tsis ua haujlwm cuam tshuam rau cov neeg mob uas muaj lub plawv tsis ua haujlwm ntev los yog lub raum tsis ua haujlwm (suav nrog renal artery stenosis). Nrog kev kuaj mob kom raws sij hawm thiab kev kho mob kom zoo, lub raum tsis ua haujlwm nrog lisinopril txoj kev kho yog feem ntau thim rov qab.

Hauv qee cov neeg mob ua mob ntshav tsis muaj ntshav tsis pom tseeb kev ua haujlwm hauv lub raum, kev kho nrog coninitant nrog lisinopril thiab diuretics qhia tau nce ntshav urea thiab creatinine. Thaum muaj tej qhov xwm txheej zoo li no, nws yuav tsim nyog txo qhov tshuaj ntawm ACE inhibitor lossis tshem tawm txoj diuretic, koj kuj yuav tsum xav txog qhov muaj peev xwm ntawm kev kuaj mob tsis pom kev mob raum.

Lisinopril txoj kev kho mob rau cov mob myocardial infarction yuav tsum tsis txhob raug rau cov neeg mob uas lub raum tsis ua haujlwm: cov ntshav tsim muaj ntau dua li 177 μmol / L (2 mg / dL) thiab / lossis proteinuria ntau dua 500 mg ib hnub. Lisinopril yuav tsum tsis ua haujlwm ntxiv yog tias lub raum ua haujlwm tsis zoo thaum lub sijhawm kho mob (ntshiab ACE Cl creatinine kuj yuav pom ntau dua li cov menyuam yaus. Yog li ntawd, cov neeg mob laus yuav tsum tau txais kev kho mob kom zoo tseem saib xyuas ntshav siab thiab raum kev ua haujlwm.

Cov menyuam. Qhov ua tau zoo thiab kev nyab xeeb ntawm lisinopril hauv cov menyuam yaus tsis tau to taub zoo, yog li nws lub sijhawm teem tsis pom zoo.

Thawj Hyperaldosteronism. Hauv thawj cov tshuaj aldosteronism, cov tshuaj tiv thaiv kev tiv thaiv kab mob, qhov kev nqis tes ua raws li kev txwv tsis pub cov kab mob renin-angiotensin, feem ntau tsis muaj txiaj ntsig, yog li, kev siv lisinopril tsis pom zoo.

Kev Proteinuria Cov teeb meem tsis tshua muaj tshwm sim ntawm kev txhim kho proteinuria tau raug sau tseg, tshwj xeeb tshaj yog nyob rau hauv cov neeg mob uas txo qis lub raum lossis tom qab noj cov lisinopril ntau txaus. Nrog rau qhov tseem ceeb ntawm cov proteinuria ntau dua (ntau dua 1 g / hnub), cov tshuaj yuav tsum siv tsuas yog tom qab ua tib zoo sib piv ntawm cov txiaj ntsig uas yuav muaj thiab cov kev pheej hmoo thiab nrog kev soj ntsuam kev kuaj mob thiab kuaj ntsuas.

LDL-phoresis / desensitization. Txoj kev kho kom haum nrog ACE inhibitors yuav ua rau muaj kev phom sij txog kev phom sij thaum lub sijhawm LDL phoresis siv cov dextransulfate. Cov kev tsis haum no (piv txwv li, poob ntshav siab, ua tsis taus pa, ntuav, tawv nqaij ua xua) kuj ua tau nrog kev teem cov lisinopril thaum kho txoj kev kho kom zoo rau cov kab (xws li muv lossis ntxhua khaub ncaws).

Yog tias tsim nyog, LDL-phoresis lossis kev kho mob kom tsis tuaj yeem ua rau cov kab tom yuav tsum tau hloov cov lisinopril ib ntus nrog lwm cov tshuaj (tab sis tsis siv ACE inhibitor) rau kev kho mob ntshav txhaws lossis lub plawv tsis ua haujlwm.

O cov ntaub so ntswg / mob caj dab (saib. "Qhov Pom Tsis Zoo"). Tsis tshua muaj cov ntawv ceeb toom hais txog mob ntsej muag, lub ntsej muag, nqaj, nplaig thiab nasopharynx hauv cov neeg mob kho nrog ACE inhibitors, suav nrog lisinopril. Edema tuaj yeem txhim kho rau txhua theem ntawm kev kho, uas nyob rau hauv cov xwm txheej zoo li no yuav tsum tau nres tam sim ntawd thiab saib xyuas tus neeg mob lub sijhawm.

Yog tias o o nyob rau ntawm lub ntsej muag thiab daim di ncauj, feem ntau nws ploj mus yam tsis tau txais kev kho mob, txawm hais tias antihistamines yuav siv los txo cov tsos mob.

Txoj kev pheej hmoo ntawm kev tsim mob angioedema thaum kho nrog ACE inhibitors yog qhov siab dua rau cov neeg mob uas muaj keeb kwm ntawm mob angioedema uas tsis cuam tshuam nrog kev siv ACE inhibitors.

Mob taub hau ntawm tus nplaig thiab lub qhov ntswg yog qhov kev hem thawj rau lub neej. Hauv qhov no, kev ntsuas maj nrawm tau qhia, suav nrog kev tswj hwm sc sai ntawm 0.3-0.5 mg ntawm adrenaline lossis qeeb qeeb ntawm kev tswj hwm ntawm 0.1 mg ntawm adrenaline thaum saib xyuas ECG thiab ntshav siab. Tus neeg mob yuav tsum tau pw hauv tsev kho mob. Ua ntej tso tawm ntawm tus neeg mob yuav tsum tau soj ntsuam yam tsawg 12-24 teev, kom txog rau thaum tag nrho cov tsos mob ploj tag.

Aortic stenosis / hypertrophic cardiomyopathy. ACE cov tshuaj tiv thaiv yuav tsum tau siv nrog ceev faj hauv cov neeg mob uas muaj qhov cuam tshuam ntawm cov ntshav tawm los ntawm cov leeg ventricle. Nrog kev nrum nrog hemodynamically, lisinopril yog contraindicated.

Neutropenia / agranulocytosis. Tsis tshua muaj mob neutropenia lossis agranulocytosis tau raug sau tseg hauv cov neeg mob mob ntshav ncig cov ntshav tau kho nrog ACE inhibitors. Lawv tsis tshua pom muaj kev cuam tshuam txog kev mob ntshav siab, tab sis muaj ntau dua rau cov neeg mob uas lub raum tsis ua haujlwm, tshwj xeeb tshaj yog nrog cov leeg mob ntawm cov leeg ntshav los yog cov nqaij mob sib kis (piv txwv li cov kab mob lupus erythematosus lossis dermatosclerosis) lossis tib lub sijhawm kho nrog immunosuppressants. Cov neeg mob li no tau qhia txog kev soj ntsuam cov ntshav dawb. Tom qab rho ntawm ACE inhibitors, neutropenia thiab agranulocytosis ploj lawm.

Thaum lub cev kub nce ntxiv, muaj qog ntau ntxiv thiab / lossis mob qa thaum kho mob, koj yuav tsum sab laj nrog kws kho mob tam sim ntawd thiab txiav txim seb qhov ntshav siab nyob hauv ntshav npaum li cas.

Muaj kev cuam tshuam kev phais / ua kom loog. Hauv cov neeg mob phais mob hnyav thiab tau txais cov tshuaj loog dav dav nrog cov tshuaj ntshav qis dua, lisinopril txwv tsis pub tsim cov tshuaj angiotensin II vim tias muaj kev tiv thaiv zoo ntawm renin. Yog tias txoj hlab ntshav hauv txoj hlab ntshav nce mus txog qhov tshwm sim, nws tuaj yeem kho kho los ntawm kev rov ua kom tiav qhov dej ntim (saib "Kev Sib Cuag").

Yog tias kev mob ntshav siab lossis mob plawv tsis ua haujlwm ntev, kev pib kho, nrog rau kev hloov pauv koob tshuaj, yuav tsum tau ua hauv tsev kho mob.

Xws li kev noj cov tshuaj hauv cov tshuaj hauv qab lossis cov koob tshuaj hla dhau, nws tsis tuaj yeem lees txais ob npaug ntawm koob tshuaj tom ntej. Tsuas yog tus kws kho mob tuaj yeem nce lub koob tshuaj.

Thaum muaj kev cuam tshuam ib ntus lossis tsum tsis ua haujlwm ntxiv los ntawm kev kho mob hauv cov neeg mob plawv tsis ua haujlwm, cov tsos mob yuav rov tshwm tuaj. Tsis txhob cuam tshuam kev kho mob yam tsis tau sab laj nrog kws kho mob.

Tsis muaj kev tshawb fawb txog cov nyhuv ntawm cov tshuaj no ntawm lub peev xwm ntawm kev tsav tsheb. Txawm li cas los xij, ib qho yuav tsum coj mus rau hauv tus lej muaj peev xwm tsis muaj peev xwm tsav lub tsheb thiab cov tshuab, nrog rau kev ua haujlwm tsis muaj kev txhawb nqa vim muaj qee zaum kiv taub hau thiab nce qaug zog.

Yeeb tshuaj sib cuam tshuam

Muaj cov ntaub ntawv hais txog kev cuam tshuam ntawm cov tshuaj Lisinopril Stada nrog rau lwm cov tshuaj: • Kev sib koom tes nrog kev siv tshuaj diuretics txhawb kev cuam tshuam ntawm kev txo cov ntshav siab, txawm tias cov ntsuas uas cuam tshuam rau kev noj qab haus huv. Yog tias ua tau, cov tshuaj diuretics yuav tsum tau txwv ua ntej kev kho mob. • Nrog kev ceev faj, koj yuav tsum haus dej haus lisinopril ua ke nrog rau txhua txoj kev muaj cov poov tshuaj, vim qhov no yuav ua rau ntau qhov kev tso siab hauv lub cev, • Kev nce siab hauv cov tshuaj tiv thaiv kab mob tuaj yeem ua rau cov tshuaj noj nrog sedatives, • Txo tus nqi ntawm cov tsis ua haujlwm ntawm lithium los ntawm lub cev thaum noj Lisinopril Stad, yog li ntawd, qhov ntsuas no yuav tsum tau saib xyuas thaum lub sijhawm kho mob. • Kev npaj rau kev kho mob ntawm lub siab thiab lwm yam kab mob muaj kua qaub ntawm lub plab hnyuv, txo qis kev nqus ntawm cov tshuaj nquag. Colestyramine muaj qhov tshwm sim zoo ib yam. • Kev tswj hwm ntawm lisinopril nrog cov tshuaj insulin thiab lwm cov tshuaj tiv thaiv kab mob muaj peev xwm txo qis cov ntshav qabzib hauv cov ntshav mus rau 3.5 mmol / L, uas pom tias yog kab mob pathological. • Kev siv cov tshuaj pleev xim, tshuaj tiv thaiv kev ua kom tsis haum tshuaj uas tsis yog steroidal keeb kwm, pab txhawm rau txhawm rau kub taub hau thiab cov txheej txheem mob, txo cov haujlwm ntawm lisinopril kom txo qis ntshav siab. • Cov tshuaj muaj kub uas siv los kho kev mob caj dab tuaj yeem, thaum noj nrog lisinopril, tuaj yeem ua rau cov hlab ntshav dhau ntawm lub ntsej muag, liab ntawm daim tawv nqaij, ntuav, xeev siab. • Cytostatic, tshuaj antiarrhythmic, xanthine oxidase inhibitors, thaum ua ke nrog lisinopril, tuaj yeem ua rau cov ntshav dawb hauv lub cev txo qis. • Kev siv cov tshuaj sib xyaw ua ke tau tso cai ua ke nrog cov tshuaj uas ua rau thaiv kev sib txuam ntawm cov tshuaj tiv thaiv betoadrenoreceptors, nitrate tshuaj, tshuaj uas pab tua cov ntshav khov ntau dhau. • Thaum noj nrog cov tshuaj acetylsalicylic acid, cov koob tshuaj ntawm lub tom kawg yuav tsum tau ua kom tsawg, txhawm rau txhawm rau tiv thaiv qhov txo qis hauv txoj kev kho. Qhov pom zoo koob tshuaj acetylsalicylic acid tsis ntau tshaj 300 mg rau ib hnub.

Cov lus thiab cov xwm txheej ntawm kev cia

Khaws cov tshuaj rau hauv qhov chaw tiv thaiv los ntawm ya raws thiab ncaj qha tshav ntuj. Pom zoo kom sov tsis tshaj 25 degrees Celsius. Khaws tsis ncav cuag ntawm cov menyuam yaus. Lub txee lub neej ntawm cov tshuaj Lisinopril Stada yog 3 xyoos txij li hnub ntau lawm tau qhia ntawm pob. Thaum muaj kev tas sij hawm, nws yog txwv tsis pub noj cov tshuaj - nws yuav tsum tau muab pov tseg rau hauv kev ua raws li cov kev tiv thaiv tsim nyog.