Langerin: tshuaj xyuas txog cov tshuaj, nqe, lus qhia

rau kev kho mob

dyucha recovina: metformine

Langerin 500: 1 ntsiav tshuaj ntawm metformin hydrochloride 500 mg, sib npaug 390 mg metformin,

Langerin 850: 1 ntsiav tshuaj ntawm methyl metformin hydrochloride 850 mg, sib npaug rau 662.9 mg metformin,

Langerin 1000: 1 ntsiav tshuaj ntawm metformin hydrochloride 1000 mg, sib npaug 780 mg metformin,

cov lus ntxiv: sodium starch, dej 40, silicic acid anhydrous dej, pob kws nplej siab, magnesium stearate, barley Sepifilm bilium 752 (hypromellose, macrogol-2000-monostearate, titanium dioxide), macrogol.

Likarska daim ntawv. Cov ntsiav tshuaj, hauv lub plhaub.

Cov tshuaj pab pawg kho mob. Antidiabetic hassle. Qhov ncauj hypocliticemia. PBX code A10BA02.

- Insulonezononezhny Tsukrov ntshav qab zib hom II, yog riven zucchar hauv cov ntshav tsis txaus pridtrimuvati tsawg dua li dyutoy, cov cai ntawm lub cev thiab qis dua masi tila,

- nrog rau cov tshuaj insulin - nyob rau hauv cov mob hlwb ntshav qab zib hom I, nws yog qhov tshwj xeeb ua kom tig rov qab cov kauj ruam, uas yuav tau ua pov thawj nrog kev muaj peev xwm tiv thaiv cov tshuaj insulin.

Tus kab mob ntshav qab zib keto acidosis, mob ntshav qab zib precoma thiab coma,

tsis hnov ​​lus muaj nuj nqi nirok,

Gostrіi zhvoryuvannya, scho igry іz іz rіzіkom txoj kev loj hlob ntawm qhov ploj ntawm kev ua haujlwm nirok: lub cev qhuav dej (nyob rau hauv cov ntaub ntawv ntawm mob raws plab, ntshav), txaus ntshai, mob hnyav іnfektsііnі zhvoryuvannya, dhau los txwv, sepsis,

Cov kev mob tshwm sim tseem ceeb ntawm gostrich thiab mob zhoryvoryvan, uas tuaj yeem coj mus rau kev txhim kho cov nqaij mos hypoxia (mob plawv yog dichromic insufficiency, gostrii myocardial infarction),

phais mob hnyav thiab raug mob (yog tias tsim nyog, ua rau muaj kev kho mob),

lub luag hauj lwm tawg,

cawv ntev mus, gostre otruєnny haus cawv,

rhiab rau metformin lossis rau cov tshuaj ntawm cov tshuaj,

chaw mos thiab xyoo ntawm lub mis,

lactic acidosis (suav nrog keeb kwm),

dotrimannya gіpokalorіyno dієti (tsawg tshaj іzh 1000 cal / ext),

tus menyuam wik mus txog 10 lub pob zeb.

Nws tsis pom zoo kom txhav Langerin rau cov neeg laus dua 60 xyoo, uas yuav muaj lub cev zoo, uas tsim nyog los tsim cov lactic acidosis hauv lawv.

Sposib zososuvannya li dozi.

Cov me nyuam dhau 10 pob zeb

Mono kev kho mob thiab kev sib koom ua ke nrog kev tuav pov hwm

Pochatkova warehouse dozє 1 ntsiav tshuaj 500 mg lossis 850 mg 1 zaug ib dob. Tom qab 10-15 hnub, koob tshuaj ntawm corigovati tom ntej yog qhia kom txog rau thaum cov ntshav muaj piam thaj. Povіlnee pіdvыchenny dosuvannya moget tsawg zaus cov kev mob tshwm sim ntawm txoj kev phiv txoj hnyuv sab.

Qhov siab tshaj plaws dobova koob tshuaj yog 2000 mg (rosodiene rau 2-3 priyomi).

Mono kev kho mob thiab kev sib xyaw nrog tshuaj tiv thaiv kab mob hauv lub qhov ncauj

Pochatkova koob tshuaj rau Langerin warehouseє 500 mg 2-3 zaug rau ib doba lossis 850 mg 2 zaug ib doba. Tom qab 10-15 hnub, koob tshuaj ntawm corigovati tom ntej yog qhia kom txog rau thaum cov ntshav muaj piam thaj. Cov tshuaj ntau dua tuaj yeem txo qhov tsawg zaus ntawm cov kev mob tshwm sim los ntawm cov nyhuv ntawm txoj hnyuv.

Qhov siab tshaj plaws dobova koob tshuaj yog 3000 mg.

Thaum lub sijhawm hloov mus rau thawj qhov ncauj tshuaj tiv thaiv kab mob hauv lub qhov ncauj, noj tshuaj ntxiv rau lwm zaus Kuv xav kho qhov kev xa khoom noj ntawm cov khoom noj kwv yees nrog ib koob tshuaj metformin.

Ua ke nrog cov tshuaj insulin

Yuav kom ua tiav qhov kev tswj hwm ntawm glikemії luv, nws muaj peev xwm txhim kho cov metformin thiab kev sib xyaw ntawm kev sib txuas. Zvichain pochatkova koob tshuaj Langerin warehouse muaj 500 abo 850 mg 2-3 zaug ib koob, nyob rau lub sijhawm ntawd, yog ib koob tshuaj insulin nws tuaj yeem corroborate ntshav qab zib ua ntej ntshav.

Muab faib rau lub Ntiaj Teb

Vrachovuchi muaj peev xwm ua kom tsawg dua ntawm cov kev ua haujlwm hauv cov neeg mob uas tau txhaj tshuaj me me ntawm metformin raug kho rau qhov ua haujlwm ntawm nirok. Nws yog ib qho tsim nyog yuav tsum rov ntsuam xyuas qhov haujlwm ntawm nirok tsis tu ncua.

Tsis tseem ceeb ntawm kev kho mob yog qhia los ntawm txo qis qis thiab cuam tshuam ntawm kev qaug dab peg.

Siv tshuaj noj, noj nws, noj nws, tos ib hnub twg, lossis noj nws.

Pobichny kev tawm tsam.Puas tsuaj rau ntawm sab ntawm slag-plab hnyuv: xeev siab, kev nyuaj siab, "hlau" nti hauv lub qhov ncauj, kem plab, tsis qab los, noj mov tsis haum plab, raws plab, mob plab. Cov tsos mob feem ntau yog ncau tawm tshwj xeeb tshaj yog nyob ntawm tus nqaj dej, thiab raws li txoj cai, lawv paub lawv tus kheej ntawm lawv tus kheej. Cov tsos mob no hloov pauv nrog tus mob antacid, atopic atropine, thiab spasmolytic. Txhawm rau kom tau ntuj raug txim tawm ntawm cov kev mob tshwm sim no, nws raug nquahu kom koj pib cov tshuaj rau ib nrab ib teev, lossis tsawg kawg 2-3 zaug ib zaug ntxiv. Yakshcho dyspeptic tsos mob __, lіkuvannya tshuaj slіd priniti.

Wrecked nyob rau sab obmіnu rechovin: lactic acid dyatez (Kuv yuav xav tau vіdmіni lіkuvannya), nrog tsis tseem ceeb lіkuvannі - gіpovіtamіnoz V₁₂ (tsaus muag txhua lub sijhawm).

Ua rau puas rau ntawm cov ntshav: nyob rau hauv okremich vipadakh - anemia yog megaloblastic.

Kev tsis haum tshuaj: Visip rau shkіrі.

Noj ntau dhau. Nrog metastasis metformin ntawm ib koob ntawm 85 g, kev txhim kho ntawm hypoglycemia tsis ua tsis tiav. Ale nyob rau hauv tsyuyu vipadka rooted lactic acidosis. Cov tsos mob thaum ntxov ntawm tus kab mob lactic acidosis yog є xeev siab, blues, raws plab, qhov kub nce ntxiv, lub plab, lub plab thiab mummy, hauv qhov deb tuaj yeem nkag mus rau hauv kev tsis meej pem, ua kom puas ntsoog thiab tso dag.

Likuvannya: tshwm sim hauv vipadok uas muaj cov cim ntawm cov kab mob lactic acidosis ntawm cov tshuaj, koj yuav tsum txhawm rau txhawm rau, muaj cov tshuaj tiv thaiv zoo hauv tsev kho mob, qhia txog qhov concentration ntawm lactate, qhia meej kev kuaj mob. Naybilsh hauv txoj hauv kev zoo nrog kev qhia txog kev ua kab mob lactate thiab kev npaj препара hemodialysis. Kuj tseem ua mob lіkuvannya.

Zastosuvannya nyob rau lub sijhawm ntawm vaginosti abo xyoo ntawm lub mis. Yog tias koj tau npaj tawm vaginosti, thiab tseem muaj vipad, vaginostnosti ntawm keeb kwm ntawm kev noj tshuaj, koj yuav tsum nco ntsoov thiab kos npe rau kev kho mob insulin. Leej niam thiab cov me nyuam tshiab tau ceev faj heev.

Nta zastosuvannya. Raws li txoj cai, tus neeg mob tau nyuaj siab, mob plab, mob plab, tsis muaj zog thiab muaj zog yog unbridled, ces kuv nrov nrov pinned nws. Muab cov tsos mob no, koj tuaj yeem tau txais ib qho zoo rau pob ntseg ntawm lactic acidosis.

48 xyoo ua ntej 48 xyoo, tom qab xoo hluav taws xob xoo hluav taws xob (duab thaij duab, sab hauv sab hauv), kev haus tshuaj ntxiv yuav tsum noj.

Ib yam li metforminom swb 48 xyoo ua ntej ua hirurgicheskoe yov rov qab nrog tshuaj loog thiab rov qhib dua tsis dhau 48 xyoos tom qab hirurgicheskoy kev khiav haujlwm.

Langerin tsis yog qhov zoo tshaj rau haus cawv.

Kev noj qab haus huv xav tau kom nce cov tshuaj tiv thaiv nrawm thaum siv tsheb thauj khoom los ntawm txhua txoj kev. Langerin tsis yog ib qho ua kom muaj ntshav qab zib, uas yog tib lub hauv paus rau stagnation hauv lub zeem muag ntawm kev kho mono. Yog tias koj txaus siab rau qhov xwm txheej tseem ceeb tshaj plaws (insulin, anti-diabetics, sulfonylase thiab repaglination zoo dua), koj tuaj yeem hloov mus rau metforminosis. Tso cai rau koj los cuam tshuam qhov tsis zoo ntawm cov dyalnost, xws li kev kub ceev ntawm lub hlwb thiab lub cev qhov cuam tshuam, lees txais kev txiav txim siab sai (piv txwv li, saib xyuas kev thauj teeb meem, kev pabcuam tsheb thiab kev siv tshuab, tom qab ntawd ua haujlwm).

Kev sib txuam nrog cov tabs tseem ceeb tshaj plaws thiab pom kev sib hloov khoom. Tsis pom zoo kom pw thaum hmo ntuj primenom danazolu rau lub cim giperglіkemіchno dії seem. Yog tias koj yuav tsum muab cov tshuaj danazol thiab rov qab kho qhov koob tshuaj, noj cov tshuaj kom raug nrog kev tswj hwm tus so ntawm lub ntsej muag.

Kev haus dej cawv nrog cawv pab txhim kho cov kab mob lactic acid ntawm ib teev ntawm lub xeev ntawm kev haus dej cawv, tshwj xeeb tshaj yog nyob rau hauv kev tshaib plab, tab sis ntxiv rau cov zaub mov tsis muaj calorie tsawg, zoo li thaum tsis haum. Anд ib teev mus rau priyomuyu yeeb tshuaj slіd unikati priyyu cawv і lіkarskikh zasobіv, scho kua zaub ntsuab cawv.

Kev sib xyaw ua ke uas xav tau kev saib xyuas tshwj xeeb

Chlorpromazine: thaum noj hauv koob tshuaj loj (100 mg rau ib dob), Kuv tabtom noj tshuaj glіkemіy, txo qis qis ntawm qib insulin. Thaum hais txog kev tawm tsam tshuaj thiab tshuaj noj, Kuv yuav muab cov feem tsim nyog tau kho nrog qhov kev tswj hwm ntawm pawg neeg hauv pawg.

Glucocorticosteroid (GCS) cov txheej txheem hauv cov kab ke thiab txo qis kom muaj qabzib cov ntshav siab, ua kom lub cev txhaws, thiab tiv thaiv ketosis. Yog tias koj muaj GCS thiab Kuv tau sau cia kom noj cov tshuaj tas, kho cov koob tshuaj nrog kev tswj hwm ntawm kev tswj hwm ntawm GLI.

Kev Khomob: kev txais tos ib-teev ntawm lub voj dyuretics tuaj yeem ua rau kev loj hlob ntawm cov kab mob lactic acidosis los ntawm maliru nirkov tsis txaus.

Yodvmіsnі radiocontrast hais lus: Kev tshawb nrhiav hluav taws xob xoo hluav taws xob xoo hluav taws xob xoo yuav muaj feem ua rau cov kab mob lactic acidosis hauv cov neeg mob ntshav qab zib lossis cov ua haujlwm tsis zoo. Txhawb nqa cov tshuaj no qeeb dua 48 xyoos ua ntej thiab tsis txhob hnov ​​mob ua ntej hnub nyoog 48 xyoo tom qab kev kuaj mob xyoo dhau los hauv radiopaque rechinov.

Raug xaiv los ntawm viglyad єн'єкцій b₂sympathomimetic: Txhawb Nqa Cov Lus Txhais ntawm Kev Txhawb Nqa b₂-thawj coj. Ntawm tsyomu vipad potroben tswj glikemії. Yog tias tsim nyog, tau pom zoo kom teem sijhawm pom zoo.

Nrog rau kev siv ib zaug tshuaj nrog cov tshuaj kawg sulfonylsechovini, insulin, acarbozoy, salicylates, koj tuaj yeem ntxiv dag zog nws.

Cov tub ceev xwm Pharmacological.Cov Tshuaj Hauv Tshuaj. Metformin - ib qho loj nrog ib qho tawm tsam-hyperglycemic nyhuv, uas txhais tau tias kuv txo qis hyperglycemia, tsis ua rau muaj kev loj hlob ntawm hyperglycemic. Kuv tsis txhawb kev tsim cov tshuaj insulin thiab kuv tsis ua rau muaj kev phom sij rau cov neeg noj qab nyob zoo.

Metformin pidvishchu qhov tseem ceeb ntawm cov khoom siv sab nrauv rau insulin thiab kev siv ntshav qabzib los ntawm clitins. Upovlennyu gluconeogenesis nyob rau hauv daim siab. Kuv yuav yuag yuag tag nrho cov carbohydrate hauv plab hnyuv. Kev haus tshuaj ua rau muaj qhov tshwm sim zoo nyob rau hauv cov metabolism ntawm lipids: Kuv muaj lub peev xwm qis dua los zes roj, thiab qis dua cov roj cholesterol thiab peb glycerides.

Cov Tshuaj Pharmacokinetics. Thaum metastasis sab hauv yog metformin nqus ntawm qhov mob plab hnyuv, feem ntau, nrog quav, 20-30% ntawm qhov koob tshuaj yog pom. Kev tsis txaus ntseeg txog kev muaj peev xwm ntawm kev ua 50% mus rau 60%. Nrog rau kev lees paub ib zaug, cov metformin yog txo thiab daws.

Metformin shvidko rozpodilyaetsya hauv cov ntaub so ntswg, nws yog qhov ua tau kom tsis txhob koom tes nrog cov protein plasmas. Metformin metabolism yog qhov tsis muaj kev thaj yeeb nyab xeeb thiab ua rau nirka.

Nirkovy klirens metformin ua> 400 ml / hv. Rau qhov muaj txiaj ntsig ntawm cov neeg uas xav ua kom zoo dua ntawm lub club, lub club ua rau muaj kev lim dej zoo nkauj thiab tubular tso dag. Kintseviy lub sijhawm nyob rau pіvzhitty pіslya qhov ncauj cov thawj coj nyob rau hauv lub tsev rau khoom metformіnu kwv yees li 6,5 xyoo.

Nrog lub tawg nirkov funktsion nirkov klirens metformіnu txo hauv kev faib ua feem rau creatine tshiab klirensu. Lub sij hawm txaus yuav ua tau, theem ntawm metformin hauv plasma zrosta.

Lub cev thiab tshuaj siv hluav taws xob:

Langerin 500: bіlі roundі, ntsiav tshuaj biconvex, sab hauv plhaub,

Langerin 850: bilium oval ntsiav tshuaj, sab hauv plhaub, nrog kev pheej hmoo ntawm kev pheej hmoo ntawm ib sab,

Langerin 1000: bilі oval ntsiav tshuaj, sab hauv plhaub, nrog kev pheej hmoo ntawm kev pheej hmoo ntawm ob sab.

Lub sij hawm ntawm txuas. 3 Pawg zeb.

Ntxuav cov zberigannya. Kuv yuav tsis xav tau tshwj xeeb lub siab zoo zberigannya. Zberigati tawm ntawm qhov chaw ncav cuag cov menyuam yaus.

Ntim. 10 ntsiav tshuaj rau hlwv, 3 rau 6 txhua, lossis 9 rau 9 blister ntim.

Qeb vіdpusku. Rau hauv daim ntawv qhia.

Virobnik. AT "Zentiva".

Сцезнаходження. Нітрянська, 100, 920 27 Hlohovec, Slovak Republic.

Tshuaj thaj tsob thiab cov cim rau kev siv

Lub tshuab nruab nrab ntawm kev ua ntawm qhov tseem ceeb ntawm cov tshuaj cuam tshuam nrog nws lub peev xwm los txwv cov txheej txheem ntawm gluconeogenesis, nrog rau cov txheej txheem ntawm kev ua ke ntawm cov roj ntsha dawb thiab ua kom muaj roj oxidation. Ib tus neeg sawv cev ntawm chav kawm biguanide tsis cuam tshuam rau qhov tshuaj insulin tso rau hauv cov ntshav, tab sis hloov nws cov chaw muag tshuaj los ntawm kev txo qis ntawm qhov khi ntawm cov kua insulin kom pub dawb thiab nce qhov feem ntawm insulin rau proinsulin.

Lub ntsiab lus tseem ceeb hauv cov txheej txheem ntawm kev nqis tes ntawm cov ntsiav tshuaj xws li yog qhov kev xav ntawm cov piam thaj kev qog los ntawm cov leeg hlwb.

Qhov tseem ceeb tshaj plaws rau kev siv tshuaj yog kev txhim kho ntawm cov tshuaj insulin-ntshav qab zib hauv ib tus neeg, tshwj xeeb tshaj yog nrog kev tsis muaj txiaj ntsig ntawm kev noj zaub mov ua raws.

Cov khoom tseem ceeb ntawm Langerin muaj xws li:

• txo cov ntshav glycated hemoglobinꓼ
• nruab nrab cov tshuaj insulin tsis ua haujlwm ntawm cov qe rau cov tshuaj hormones insulin
• favorably cuam tshuam qhov normalization ntawm lipid profile ntawm ntshav ntshav ꓼ
• txo cov roj (cholesterol) phem

Tsis tas li ntawd, kev siv cov tshuaj muaj peev xwm ua kom lub cev qhov hnyav.

Cov lus qhia rau kev siv ntsiav tshuaj

Cov tshuaj Langerin yog muaj nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj coated.

Cov ntawv ntim rau hauv lub hnab yas, uas tau ntim nrog txhuas ntawv ci.

Cov ntim khoom tau muab tso rau hauv lub thawv ntawv thawv nrog cov lus qhia rau kev siv tshuaj.

Ua raws li qhov xav tau ntawm cov tshuaj tau siv, cov tshuaj tuaj yeem tuaj yeem yuav nrog ntau npaum li cas:

1. 500 milligrams.
2. 850 milligrams.
3. Ib qho ntawm cov tshuaj muaj zog.

Cov qauv ntawm kev noj cov ntsiav tshuaj yog qhov ncauj, ntawm lub sijhawm noj mov lossis tom qab nws. Tus kws kho mob uas tuaj koom yuav sau ib qho tshuaj rau txhua tus neeg mob nyob ntawm seb tus kab mob loj npaum li cas. Tsis tas li, tus kws kho mob tshwj xeeb txiav txim siab noj tshuaj ntau npaum li cas thaum nruab hnub.

Langerin-cov lus qhia rau kev siv pom zoo pib ib chav pov thawj ntawm kev kho mob nrog kev noj tshuaj tsawg kawg 500 mg ntawm cov tshuaj nquag. Tus naj npawb ntawm cov koob tshuaj ntawm lub tshuaj nruab hnub yuav ua tau li ntawm ib mus txog peb. Maj mam, ntau npaum li cas ntxiv tau nce rau 850 mg ntawm cov tshuaj nquag thoob plaws ib hnub (ib zaug ob zaug hauv ib hnub). Cov kws kho mob koom nrog saib xyuas qhov mob ntawm tus neeg mob thiab, tsis pub ntau tshaj ib zaug ib lim tiam, kho cov tshuaj ntawm cov tshuaj noj tau nce siab.

Cov tshuaj no tseem tau sau tseg txog kev kho mob rau tus menyuam hauv ntau tshaj kaum xyoo. Kev kho mob Monotherapy yuav tsum pib nrog kev noj tshuaj ntawm 500 mg ntawm cov tshuaj nquag ib zaug lossis ob zaug ib hnub. Tom qab qee lub sijhawm, maj mam nce ntxiv ntawm cov koob tshuaj tau tso cai, tab sis tsis pub ntau tshaj ob grams hauv ib hnub, muab faib ua ob lossis peb koob tshuaj.

Feem ntau, kev hloov pauv hauv cov ntau npaum li cas ntawm cov tshuaj tshwm sim tom qab kaum txog kaum tsib hnub raws li cov txiaj ntsig ntawm kev ntsuas ntshav rau cov piam thaj.

Qee qhov xwm txheej, kev npaj ntsiav tshuaj yog ib feem ntawm kev sib txuas ua ke nrog kev siv tshuaj insulin.

Nws yuav tsum raug sau tseg tias kev tswj hwm ib txhij ntawm Langerin nrog cov tshuaj insulin, sulfonylurea derivatives, acarbose, lossis ACE inhibitors yog pom kom nce cov nyhuv hypoglycemic ntawm cov tshuaj.

Qee qhov xwm txheej, tus kws kho mob mus koom yuav hloov qhov kev siv Langerin nrog cov ntsiav tshuaj ntawm cov sib xws. Niaj hnub no, muaj tshuaj ntau ntau, lub ntsiab tseem ceeb ua ke ntawm uas yog metformin.

Tus nqi ntawm cov tshuaj analog tuaj yeem sib txawv, nyob ntawm seb lub tuam txhab ntawm cov chaw muag tshuaj.

Dab tsi yog cov contraindications rau siv?

Cov tshuaj noj tsis raug cai lossis tsis ua raws li cov lus pom zoo ntawm tus kws kho mob tuaj yeem ua rau pom kev phiv tshuaj tsis zoo thaum noj cov tshuaj.

Ntxiv rau, muaj qee kis hauv kev siv tshuaj yeeb tshuaj raws li metformin yog txwv tsis pub.

Cov lus qhia rau kev siv tshuaj qhia cov npe ntawm lub ntsiab contraindications.

Lub ntsiab contraindications rau kev siv ntawm Langerin ntsiav tshuaj suav nrog cov hauv qab no:

• kev ua rau mob siab lossis lub raum tsis ua haujlwm, lawv qhov tsis txaus
• cawv, suav nrog nyob rau hauv mob ntev formꓼ
• mob plawv los yog kev ua pa tsis ua hauj lwm
• mob myocardial infarctionꓼ
• kev mob nkeeg uas tsis yog mob ntshav qab zib coma lossis poj koob yawm txwvꓼ
• kev loj hlob ntawm tus mob ko taw mob ko taw syndromeꓼ
• nyob rau hauv ib puag ncig ntawm ib tug neeg intolerance rau metformin thiab kev loj hlob ntawm kev tsis haum rau lub componentꓼ
• muaj cov kis mob sib kis-
• yoo mov nrog cov ntshav qab zib lossis ua raws li kev noj haus uas nws noj txhua hnub tsis pub dhau ib txhiab kilocaloriesꓼ
• ua ntej thiab tom qab phaisꓼ
• nrog cov kev raug mob uas tsis ntev los noꓼ
• ua ntej thiab tom qab kev kuaj mob uas siv lub xov tooj cua isotropes ntawm iodineꓼ
• ketoacidosis thiab mob lactic acidosis.

Ntxiv rau, cov poj niam yuav tsum tsis txhob noj cov tshuaj thaum cev xeeb tub thiab lactation.

Qhov tshwm sim ntawm kev mob tshwm sim tuaj yeem tshwm sim nws tus kheej rau ntawm ib feem ntawm ntau yam plab hnyuv siab raum thiab cov kab ke ntawm tib neeg lub cev - lub plab zom mov, metabolism, kab mob plawv, kab mob ntawm daim tawv nqaij. Cov kev tshwm sim tsis zoo uas tshwm sim los ntawm kev noj tshuaj yog:

1. Txhawb siab flatulence. Qee zaum xeev siab tshwm sim hauv ntshav qab zib hom 2. Xeev siab yuav hloov pauv ntuav.
2. Kev mob plab mog.
3. Cov tsos ntawm cov xim hlau sib xyaw hauv qhov ncauj kab noj hniav.
4. Hematopoiesis thiab hemostasis.
5. Megaloblastic anemia.
6. Txo cov ntshav qab zib kom qis dua cov qib uas siv tau - hypoglycemia.
7. Cov tsos ntawm tsis muaj zog hauv lub cev.
8. Kev nkees nkees.
9. Kev Ntshav.
10. Kev ua pa ntawm lub siab.
11. Cov tsos ntawm dermatitis lossis ua pob rau ntawm daim tawv nqaij.

Ceev faj yuav tsum tau noj thaum noj Langerin nrog lwm cov tshuaj. Kev siv ua ke nrog cov ntsiav tshuaj nrog cymeditine nce kev pheej hmoo ntawm cov kab mob lactic acidosis. Kev sib xyaw ntawm Langerin nrog lub voj diuretics tuaj yeem txhim kho tib lub txiaj ntsig. Hauv qhov no, ntxiv rau qhov ua rau muaj kev tawm tsam ntawm cov kab mob lactic acidosis, ib qho kev pom ntawm lub raum tsis ua haujlwm tuaj yeem pom.

Siv cov tshuaj, nws yog ib qho tsim nyog los saib xyuas kev ua haujlwm ntawm lub raum thiab txiav txim siab cov lactate hauv ntshav tsawg kawg ob zaug hauv ib xyoos.

Cov lus qhia txog cov tshuaj siv los kho ntshav qab zib tau muab tso rau hauv cov yeeb yaj kiab hauv tsab xov xwm no.

Lub Npe Tsis Muaj Npe International

Lub npe thoob ntiaj teb zoo ib yam nrog lub npe ntawm cov tshuaj nquag - Metformin (metformin).

Langerin siv los txo cov ntshav qab zib.

ATX code yog A10BA02 tus lej.

Tso cov ntaub ntawv thiab cov nyob ua ke

Cov tshuaj muaj tsuas yog hauv cov qauv ntawm cov ntsiav tshuaj rau kev tswj hwm ntawm qhov ncauj. Xws li cov yam ntxwv tau txawv - txheej, tiv thaiv kev ua haujlwm ntev, npog nrog ib txheej zaj duab xis, nrog ib txheej enteric.

Lub ntsiab nquag sib xyaw ua ke yog metformin hydrochloride. Cov neeg zam yog tam sim no: pob kws hmoov txhuv nplej siab, magnesium stearate, macrogol 6000, anhydrous colloidal silicon dioxide, povidone 40, titanium dioxide, hmoov txhuv nplej siab sodium glyflix, hypromellose, monostearate-2000-macrogol.

Cov Tshuaj Pharmacokinetics

Thaum noj cov tshuaj hauv, metformin yog nqus tag nrho los ntawm cov mob hauv plab, thaum mus txog ib feem peb yog tawm hauv lub cev nrog quav. Qhov siab tshaj plaws ntawm cov khoom siv tau mus txog tom qab ob thiab ib nrab teev. Hauv cov ntshav, cov tshuaj yeeb yaj kiab tsis ua kev sib txuas nrog cov protein; hauv cytoplasm ntawm cov qe ntshav liab, cov tshuaj sib txuas ua ke sib txuam hauv daim ntawv granules.

Txog li ib feem peb ntawm cov tshuaj raug tawm hauv lub cev nrog quav quav.

Cov Yuav Tsum Muaj

Metformin yog txwv tsis pub siv rau hauv cov xwm txheej zoo li no:

• hypersensitivity rau Cheebtsam,
• nrog rau kev ua tsis taus ntawm lub raum thiab lub siab ua haujlwm,
• nrog cawv,
• nrog cov kab mob ntawm cov kev sib kis thiab cov hlab plawv,
• ntau hom mob acidosis,
• cev xeeb tub thiab lactation
• siv cov iodine sib piv,
• nrog kev tshaib plab thiab lub cev qhuav dej.

Yuav ua li cas noj Langerin

Cov tshuaj yog npaum li cas los ntawm kev saib xyuas qib ntawm cov piam thaj hauv cov ntshav, uas tus neeg mob yuav tsum ntsuas ntau zaus hauv ib hnub: thaum sawv ntxov, tom qab txhua pluas noj, thaum yav tsaus ntuj ua ntej mus pw.

Txais tos - lub qhov ncauj thaum noj zaub mov lossis tom qab nws. Kev muab tshuaj thawj zaug yog li 500 mg rau 850 2 lossis 3 zaug ib hnub. Tom qab 2 lub lis piam, cov koob tshuaj yuav tsum tau kho raws li cov txiaj ntsig ntawm kev tshawb tshuaj glycemic.

Qhov siab ntau kawg tsis tuaj yeem dhau 3000 mg, nws tau faib ua 3 zaug.

Rau cov menyuam yaus tom qab 10 xyoo, kev muab tshuaj yog 500-850 mg rau ib hnub 1 zaug. Qhov siab ntau tshaj plaws yog 2000 mg, muab faib los ntawm 2-3 zaug.

Nrog ntshav qab zib

Cov lus qhia rau kev siv faib cov kev kho mob rau hauv kev kho mob monotherapy thiab kev sib xyaw nrog insulin. Qhov hno thawj zaug yog 500-850 mg ob zaug ib hnub nrog lossis tom qab noj mov. Ob lub lis piam tom qab, kev hloov tshuaj tsuas yog ua tiav raws li kev soj ntsuam qab zib. Txhua lub sijhawm no, tus neeg mob yuav tsum muaj tus kheej glycemic profile. Qhov tau tso cai ntau tshaj plaws yog 3 g, faib ua 3 koob.

Hauv cov kab mob ntshav qab zib mellitus, cov lus qhia rau kev siv tshuaj faib cov kev kho rau kev kho mob monotherapy thiab kev sib xyaw nrog insulin.

Phiv fab ntawm Langerin

Cov xwm txheej tsis zoo los ntawm cov plab hnyuv siab raum thiab cov tshuab yuav loj hlob.

1. Daim tawv nqaij: ua pob khaus khaus.
2. Cuam tshuam rau cov kab mob hepatobiliary: kab mob siab, ua kom daim siab ua haujlwm.
3. Cov tsos mob neurological: saj kev tsis meej.
4. Los ntawm lub plab zom mov: zoo li xeev siab, ntuav, raws plab, tsis qab los noj mov, mob plab, tsam plab, smack hlau hauv qhov ncauj.
5. Tsis tshua muaj kev hloov pauv hauv cov ntshav - megaloblastic anemia, vitamin B12 tsis txaus.

Soj ntsuam qhov ploj ploj ntawm lawv tus kheej tom qab tshem yeeb tshuaj. Muaj qee zaus, yuav tsum muaj kev kho qhov tsos mob.

Cov lus qhia tshwj xeeb

Lawv muaj hauv kev kho qhov tshuaj (feem ntau cov ntsiav tshuaj tau muab faib ua halves) thiab kawm txog qhov ua tau ntawm nws kev teem caij hauv ntau pab pawg ntawm cov neeg.

Siv rau lub sijhawm qub

Hauv cov neeg laus, cov haujlwm zoo hauv ntau lub nruab zog (lub raum, lub plawv tsis ua haujlwm) feem ntau raug kev txom nyem, yog li cov neeg mob feem ntau siv tshuaj los tswj lawv. Thiab yog tias muaj kev tsis sib xws ntawm cov tshuaj, ces koj yuav tsum tso tseg Langerin lossis hloov nws qhov ntau npaum li cas (yog tias tsim nyog, rhuav tshem cov ntsiav tshuaj ua ib nrab, noj ib qho).

Txiag tej menyuam

Cov tshuaj yog tawm rau cov menyuam muaj hnub nyoog kaum xyoo. Thaum muaj hnub nyoog yau, lwm yam tshuaj tau xaiv. Kev sim tshuaj ntawm cov menyuam yaus thaum yau tseem tsis tau ua, yog li tsis muaj ntaub ntawv qhia txog nws qhov kev cuam tshuam ntawm kev loj hlob, kev loj hlob thiab kev pub dawb ntawm menyuam, tshwj xeeb tshaj yog siv sijhawm ntev. Yog li, nws yuav tsum siv nrog ceev faj hauv pawg hnub nyoog ntawm 10-12 xyoo.

Siv thaum cev xeeb tub thiab lactation

Thaum npaj kev cev xeeb tub, koj yuav tsum tsis txhob noj Langerin thiab qhia koj tus kws kho mob txog qhov no. Nws yuav tshaj tawm cov koob tshuaj tsim nyog ntawm cov tshuaj insulin, uas yuav tsum tau siv thoob plaws hauv lub sijhawm cev xeeb tub. Cov nyhuv ntawm metformin rau tus me nyuam hauv plab tau txheeb raws li B.

Thaum npaj kev cev xeeb tub, koj yuav tsum tsis txhob noj Langerin thiab qhia koj tus kws kho mob txog qhov no.

Cov kev tshawb fawb thaum lub sij hawm pub mis niam tsis tau ua, tsis muaj cov ntaub ntawv hais txog kev nkag mus ntawm metabolites rau hauv mis, yog li ntawd, thaum lub sijhawm lactation, koj yuav tsum tso cov tshuaj.

Noj ntau dhau ntawm langerin

Thaum thov kev noj tshuaj ntau dua qhov tsim nyog, cov cim tshwm sim: lactic acidosis, lub siab qhuav hauv lub qhov ncauj ntawm lub qhov ncauj, cov qog ua pa, tawv nqaij, leeg thiab lub hauv siab mob, ua pa ceev, pw tsaug zog, ua tsis taus pa, mob tsis haum, mob plab, mob plab, ntuav, mob hauv lub plawv, oliguria, ICE. Tsis tas li, hypoglycemic tej yam kev mob tsis tsim. Tsis muaj kev kho tshwj xeeb. Raws li kev kho mob, kev lim ntshav thiab tshuaj ntxuav ntshav tau zoo siv, thiab kev kho mob cov tsos mob kuj tau ua. Yuav tsum tau tshem tawm cov tshuaj kho sai sai.

Contraindicated kev sib txuas ua ke

Yog tias nws yuav tsum tau ua txoj hauv kev uas yuav muaj cov tshuaj tiv thaiv iodine uas yuav muaj, koj yuav tsum tsis txhob noj Langerin hauv ob hnub. Thiab rov pib siv tshuaj yeeb muaj peev xwm ua tau 2 hnub tom qab kev tshawb fawb, ua ntej qhov no, kev ntsuam xyuas yuav tsum tau ua los ntsuas qhov kev ua haujlwm ntawm lub xeev hlaus. Txwv tsis pub, txoj kev txhim kho lub raum tsis ua haujlwm yog qhov ua tau, kev pheej hmoo ntawm cov kab mob lactic acidosis.

Gliformin tuaj yeem yog ib qho tshuaj sib faib ntawm cov tshuaj.

Cov tshuaj Danazol tsis raug siv rau hauv kev kho mob Langerin. Qhov no yog fraught nrog cov piam thaj siab, acidosis, thiab muaj kev pheej hmoo ntxiv ntawm kev tsis nco qab. Yog li no, glycemia yuav tsum tau saib xyuas.

Tej kev sib txuam uas xav tau ceev faj

Nrog rau kev saib xyuas tshwj xeeb, cov tshuaj yuav tsum tau siv nrog cov tshuaj tiv thaiv kab mob hauv nruab nrab lossis hauv zos, ACE inhibitors, diuretics, beta-2-sympathomimetics - cov tshuaj no tuaj yeem txo cov ntshav qab zib. Yog li, koj yuav tsum ceeb toom rau tus neeg mob txog qhov no, nrog rau kev kho cov tshuaj Langerin ntau npaum li cas.

Chlorpromazine thiab antipsychotics kuj yog cov tshuaj, nyob rau hauv kev sib xyaw nrog qhov kev siv cov tshuaj tiv thaiv ntawm metformin yuav tsum raug kho.

Cawv tau zoo

Nws yog tsis sib xws nrog haus cawv. Thaum ua ke nrog ethanol, txoj kev pheej hmoo ntawm kev tsim lub lactic acidotic xeev nce, tshwj xeeb tshaj yog muaj teeb meem nrog daim siab (daim siab tsis ua haujlwm) lossis nrog zaub mov tsis txaus.

Hloov tshuaj rau Langerin yog cov tshuaj:

• Glyformin
• Gliformin Prolong,
• Glucophage,
• Metformin
• Metfogamma,
• Rau feeb,
• Siofor hauv ntau cov tshuaj noj (1000, 800, 500),
• Vero-Metformin,
• Glycomet 500.

Xyuas hais txog Langerin

Anton, 48 xyoo, Oryol: “Kuv tau mob ntshav qab zib hom 2 tau 3 xyoos. Tus kws kho mob sau tseg cov tshuaj. Kuv zoo siab tias tsis muaj kev mob tshwm sim, thiab cov piam thaj ntau tsis nce siab. ”

Anna, 31 xyoo, Moscow: “Kuv tau mob ntshav qab zib hom 2, Kuv tau mob tau yuav luag 5 lub xyoos. Thawj xyoo nws tswj qib hauv qabzib los ntawm kev tawm dag zog thiab kev noj haus. Txawm li cas los xij, tsis muaj ib qhov kev ua tau zoo. Tus kws kho mob sau cov tshuaj no rau ntawm ib koob 850 mg ob zaug ib hnub. Tsis muaj kev mob tshwm sim. "

Vasily, 28 xyoo, Krasnodar: “Hom 2 mob ntshav qab zib tau tshawb pom ntau xyoo dhau los. Kuv tabtom yuav cov tshuaj no. Tus kws kho mob tau lees tias nws ua haujlwm zoo thiab ua kom cov ntshav qabzib nyob li qub. Nqa tau qhov tsawg kawg nkaus ntawm 500 mg. Kev siv cov tshuaj yuav tsum yog tas li, tsis muaj kev phiv, yog li kuv xav tias qhov tshuaj zoo. "