Aspikor - (Aspikor) cov lus qhia rau siv
Cov tshuaj indiscriminately inhibits enzyme kev ua cyclooxygenase 1 thiab 2 (tswj hwm kev coj ua ntawm prostaglandins).
Cov tshuaj Aspicor muaj analgesic (analgesia), anti-inflammatory thiab antipyretic zoo.
Cov tshuaj phiv tshuaj acetylsalicylic acid ua rau qeeb ntawm kev tsim cov tshuaj prostaglandins, hauv qab ntawm qhov uas hyperalgesia thiab puffiness. Txo cov prostaglandins hauv plawv lojthermoregulation (feem ntau E1) ua rau muaj kev tawm hws ntau ntxiv, nthuav dav ntawm lub lumen ntawm cov hlab ntshav ntawm daim tawv nqaij thiab, vim li ntawd, txo qis hauv lub cev kub.
Ib qho kev ua kom loog mob tau ua tiav los ntawm kev ua qees thiab qhov nruab nrab ntawm cov tshuaj. Aspicore inhibits synthesis thromboxane A2 hauv cov ntshav qe ntshav, txo qis mob ntsws vwmplatelet adhesion thiab lawv kev sib sau ua ke.
Hauv cov neeg mob uas tsis muaj kev tsis txaus siab ntawm lub hlwb angina, cov tshuaj muaj txiaj ntsig acetylsalicylic acid tuaj yeem txo kev tuag, kev pheej hmoo ntawm myocardial infarction.
Cov nyhuv antiplatelet yuav kav ntev li ib lub lim tiam tom qab noj ib koob.
Kev noj tshuaj txhua hnub ntawm 6 grams lossis ntau dua nce prothrombin lub sijhawm, inhibits synthesis prothrombin nyob rau hauv daim siab mob.
Cov tshuaj Aspicore ua rau kom ntau zaus ntxiv ntawm kev mob hemorrhagic thaum kev phais mob.
Hauv qab qaug tshuaj, muaj pluaj zog yog kho dua uric acid (raws li kev ua txhaum ntawm tubular reabsorption hauv lub raum).
Kev ntsuas rau siv
Aspicor yog tshuaj kom tseg kev hnov mob mob (cov qauv me thiab cov qib nrab) ntawm ntau yam hauv paus: mob taub hau, mob taub hau, myalgiaradicular syndrome algodismenoreaarthralgia lumbago, neuralgia, mob hniav.
Cov tshuaj yog siv rau cov tshuaj febrile tawm tsam keeb kwm ntawm kev tiv thaiv, tus mob pathology.
Cov Yuav Tsum Muaj
Aspicor ntsiav tshuaj tsis yog tshuaj rau hemorrhagic diathesis, nrog rau tus kheej daim ntawv ua tsis haum rau acetylsalicylic acid, nrog mob ntsws asthma, los ntshav los ntawm lub plab zom mov, nrog rau qhov mob thiab qhov txhab mob ntawm lub plab zom mov, kev kho mob ib leeg ntawm methotrexates, xeeb tub ntawm cev xeeb tub (thawj, thib peb txiav plaub hau), kev pub niam mis thiab menyuam yaus hnub nyoog kaum tsib.
Sab sij huam
Cov tshuaj aspicor tuaj yeem ua rau mob zawv plab, xeev siab, kev tsis haum tshuaj nyob rau hauv daim ntawv ntawm angioedema, pob khaus tawv nqaij thiab bronchospasm.
Tawm tsam keeb kwm ntawm kev kho mob, kev ua txhaum nyob rau hauv kev ua haujlwm ntawm lub raum thiab mob siab yog ua tau, kev txhim kho Reye's syndrome (kev tsim kho sai sai ntawm daim siab ua haujlwm, daim siab ua paug thiab mob hlwb), mob qog ntshav, thrombocytopeniaanemia heev.
Kev kho mus sij hawm ntev kuj yuav muaj nrog hypocoagulationviav vias thiab mob txhab ntawm lub plab zom mov, kiv taub hau, mob taub hau, ntuav, pom kev tsis sib xws,interstitial jadelos ntshav, papillary necrosis, prerenal azotemia nrog hypercalcemia thiab hypercreatininemia, o, nce cov tsos mob ntawm lub plawv tsis ua hauj lwm, aseptic meningitis, nce siab enzymes, cov tsos mob nephrotic.
Aspicor, cov lus qhia rau kev siv (Txoj kev thiab ntau npaum li cas)
Cov tshuaj aspicore noj ntawm qhov ncauj.
Nrog rau mob, febrile syndrome qhov tshuaj yog noj ntawm qhov ncauj mus txog 3 gram (qhov koob tshuaj pom zoo yog 0.5-1 grams tauj ib hnub) rau 3 koob.
Raws li cov tshuaj tiv thaiv analgesic thiab anti-inflammatory, Aspicor yog tshuaj rau hauv 325 mg.
Lub sijhawm tiv thaiv ntawm kev kho yuav tsum tsis pub ntau tshaj li ob lub lis piam.
Daim foos effervescent ntawm cov tshuaj yuav tsum tau ua ntej kom yaj hauv 100-200 ml dej. Kev tso tawm ib cov tshuaj yog 0.25-1 grams (3-4 zaug hauv ib hnub).
Noj ntau dhau
Cov uas muaj mob loj tshaj yog noj ntau dhau, ua rau lub ntsejmuag ntshav siab, lub cev tsis txau ntshai, tsis nco qab, ua npaws, ketoacidosis, mob plawv thiab ua pa nyuaj.
Thaum maj nrawm mus pw hauv tsev kho mob, siv cov tshuab hluav ncaig hluav taws xob, hlab pas plab, diuresis, hemodialysis, thiab cov tsos mob kho yuav tsum tau ua.
Kev sib txuam
Cov lus qhia rau kev siv Aspicore tsis pom zoo kom siv cov tshuaj ib txhij nrog cov tshuaj hypoglycemic hauv qhov ncauj, valproic acid, methotrexate, tshuaj tiv thaiv kab mob kev tiv thaiv, thrombolytics,cov tshuaj tiv thaiv tsis tau ntiag tug, heparin, sulfonamides, antihypertensive thiab uricosuric tus neeg sawv cev, diuretics.
Txoj kev pheej hmoo ntawm mob plab hnyuv nce ntxiv nrog kev kho mob ua ke nrog glucocorticosteroids thiab tshuaj muaj ethanol.
Aspikor muaj peev xwm nce qhov siab ntawm barbiturates, digoxin, lithium ntsev hauv cov ntshav.
Kev tsis haum ntawm acetylsalicylic acid yuav txo qis thaum kho tshuaj tiv thaiv kab mob.
Cov nyhuv hematotoxic ntawm Aspicore nce ntxiv nrog kev kho mob nrog cov tshuaj myelotoxic.
Cov lus qhia tshwj xeeb
Kev siv tshuaj Aspikor ua cov tshuaj tiv thaiv kev tiv thaiv tsis pub tsawg vim muaj qhov pheej hmoo siab ntawm kev tsim NSAIDs-mob plab.
Lub sijhawm kho mob yuav tsum tsis pub ntau tshaj 5 hnub.
Tam sim no, cov tshuaj tsis tau sau tseg rau ntawm rheumatic choreadaim ntawv sib kis khaub thuas myocarditis, nrog mob rheumatoid kev mob caj dab, nrog rau mob pericarditis thiab rheumatism.
Aspicor raug pom zoo kom yuav tsum tso tseg 5-7 hnub ua ntej txoj haujlwm tau npaj tseg.
Kev kho mob mus ntev yuav tsum muaj kev saib xyuas cov ntshav suav, kev tshawb xyuas ntawm cov quav ntawm cov ntshav khov.
Cov tshuaj muaj peev xwm muab tau teratogenic cov teebmeem.
Acetylsalicylic acid yog tawm hauv niam cov kua mis.
Cov tshuaj tuaj yeem ua rau muaj mob gout.
Tso tawm daim ntawv, ntim thiab muaj pes tsawg leeg Aspicor ®
Enteric coated ntsiav tshuaj ntawm cov xim dawb lossis yuav luag xim dawb, puag ncig, biconvex, hauv ntu ntu - homogeneous loj ntawm cov xim dawb lossis yuav luag dawb xim.
| 1 tab | |
| acetylsalicylic acid | 100 mg |
Tshwjxeeb: microcrystalline cellulose, lactose monohydrate, croscarmellose sodium, silicon dioxide colloidal (aerosil), stearic acid.
Cov tshuaj sib xyaw ua ke ntawm cov xim txheej nkag: ib lub tshuab luam ntawv ntawm methacrylic acid thiab ethyl acrylate, propipylene glycol, macrogol 4000, titanium dioxide, talc.
10 Pcs. - blister packs (1) - pob ntawv los ntawm cardboard.
10 Pcs. - blister packagings (2) - pob ntawv los ntawm cardboard.
10 Pcs. - blister packs (3) - pob ntawv ntawm cardboard.
10 Pcs. - blister packagings (6) - pob ntawv ntawm cardboard.
20 Pcs. - blister packs (1) - pob ntawv los ntawm cardboard.
Pharmacological kev txiav txim
NSAIDs, tus sawv cev antiplatelet. Lub tshuab kev ua ntawm acetylsalicylic acid yog ua raws li kev tsis tuaj yeem ua rau ntawm cyclooxygenase-1 (COX-1), vim tias muaj qhov thaiv ntawm thromboxane A 2 synthesis thiab hluav taws xob ntawm platelet aggregation. Nws ntseeg tau hais tias acetylsalicylic acid muaj lwm cov txheej txheem los txwv cov platelet sib sau, uas nthuav dav nws cov kev nthuav dav hauv ntau yam kab mob vascular.
Acetylsalicylic acid kuj tseem muaj qhov ua los tiv thaiv, ua kom loog, muaj peev xwm tiv thaiv kev ua haujlwm.
Cov Tshuaj Pharmacokinetics
Tom qab kev tswj hwm ntawm qhov ncauj, acetylsalicylic acid yog nqus tau los ntawm lub plab hnyuv me. C max hauv ntshav yog pom nyob rau nruab nrab 3 teev tom qab kev noj ntawm cov tshuaj.
Acetylsalicylic acid yauv ua ib feem ntawm cov metabolism hauv nplooj siab nrog rau kev tsim cov tshuaj ua kom lub cev tsis muaj zog.
Nws yog tawm los ntawm ob lub raum, ob qho tib si tsis hloov thiab metabolites. T 1/2 acetylsalicylic acid yog kwv yees li 15 feeb, rau cov khoom xyaw metabolites - li 3 teev
Kev Qhia Txog Aspikor ®
- kev tiv thaiv ntawm mob myocardial infarction nyob rau hauv qhov muaj kev pheej hmoo (piv txwv li, ntshav qab zib mellitus, hyperlipidemia, hlab ntsha txhaws, rog rog, haus luam yeeb, laus hnub nyoog),
- tiv thaiv kev cuam tshuam myocardial infarction,
- lub siab tsis ruaj ntseg,
- kev tiv thaiv mob stroke (suav nrog cov neeg mob qog ua ntu zus),
- kev tiv thaiv kev hloov pauv cerebrovascular,
- kev tiv thaiv ntawm thromboembolism tom qab kev phais mob thiab cuam tshuam cov leeg ntshav kev tiv thaiv (piv txwv, mob hlab ntshav o hla kev sib tsoo, carotid leeg leeg endarterectomy, hlab ntsha tsis haum, carotid artery angioplasty),
- kev tiv thaiv ntawm txoj hlab ntsws sib sib zog nqus thiab mob txhim kho ntawm txoj hlab ntsws thiab nws cov ceg (piv txwv, nrog immobilization nyob ntev ua rau muaj kev cuam tshuam loj ntawm kev phais).
| ICD-10 code | Kev taw qhia |
| G45 | Lub cev hloov mus mus los tsis ntev ischemic nres tawm tsam thiab cuam tshuam nrog cov syndromes |
| I20.0 | Tsis khov tsis khov |
| I21 | Mob myocardial infarction |
| I26 | Pulmonary embolism |
| Kuv61 | Kev mob hlwb hauv lub plawv (hemorrhagic hom ntawm cerebrovascular sib tsoo) |
| I63 | Cerebral infarction |
| I74 | Embolism thiab leeg ntshav thrombosis |
| I82 | Embolism thiab thrombosis ntawm lwm cov leeg ntshav |
Kev noj tshuaj ntxiv
Cov ntsiav tshuaj yuav tsum tau noj ntawm qhov ncauj, ua ntej noj mov, muaj dej txaus.
Kev tiv thaiv ntawm kev xav tias tsam myocardial infarction: 100-200 mg / hnub (thawj ntsiav tshuaj yuav tsum tau zom rau kom nqus sai dua).
Kev tiv thaiv kab mob siab myocardial infarction nyob rau hauv lub xub ntiag ntawm kev pheej hmoo: 100 mg / hnub.
Kev tiv thaiv ntawm cov kab mob myocardial infarction, tsis khov tsis khov, tiv thaiv mob stroke thiab hloov cerebrovascular, tiv thaiv kom tsis txhob muaj teeb meem tom qab phais mob lossis tshawb fawb tsis muaj: 100-300 mg / hnub.
Kev tiv thaiv ntawm txoj hlab ntsws sib sib zog nqus thiab mob txhaws ntawm txoj hlab ntsws thiab nws cov ceg: 100-200 mg / hnub.
Cov tshuaj yog npaj rau kev siv sijhawm ntev. Lub sijhawm kho yog txiav txim los ntawm tus kws khomob tuaj koom.
Sab sij huam
Los ntawm cov txheej txheem ua pa: xeev siab, kub siab, ntuav, mob hauv plab, mob tawm tsam ntawm lub plab mos ntawm lub plab thiab duodenum (suav nrog rau perforated), mob plab zom mov, ua haujlwm ntawm daim siab ua haujlwm siab.
Los ntawm cov txheej txheem ua pa: bronchospasm.
Los ntawm cov kab mob hemopoietic: nce los ntshav, tsis tshua muaj ntshav liab.
Los ntawm sab ntawm lub hauv nruab nrab hauv lub paj hlwb: kiv taub hau, tinnitus.
Kev tsis haum tshuaj: urticaria, Quincke's edema, phiv tshuaj anaphylactic.
Cev xeeb tub thiab lactation
Kev siv cov tshuaj salicylates hauv kev txhaj tshuaj ntau hauv thawj peb lub hlis thaum cev xeeb tub muaj feem cuam tshuam nrog kev nce ntxiv ntawm cov me nyuam hauv plab kev loj hlob tsis zoo (cais tawm ntawm lub ntsej muag, lub plawv tawg). Hauv lub hlis thib ob ntawm cev xeeb tub, salicylates tuaj yeem tsuas yog nrog kev ntsuam xyuas nruj ntawm kev pheej hmoo thiab cov txiaj ntsig.
Hauv lub sijhawm peb lub hlis ntawm cev xeeb tub, salicylates hauv kev txhaj tshuaj ntau dua (ntau dua 300 mg / hnub) ua rau muaj kev txwv tsis pub muaj mob ua haujlwm, ua ntej lub plab txhaws ntawm tus menyuam hauv plab, nce ntshav hauv niam thiab tus menyuam, thiab kev tswjfwm tam sim ua ntej yug menyuam tuaj yeem ua rau mob ntshav txhav, tshwj xeeb tshaj yog cov menyuam tsis tau yug menyuam ntxov. Kev teem caij ntawm salicylates nyob rau hauv III sijhawm ntawm cev xeeb tub yog contraindicated.
Salicylates thiab lawv cov metabolites hauv ib qho me me yog tawm hauv cov kua mis. Kev noj cov salicylates ntau thaum lub sijhawm lactation tsis yog nrog kev txhim kho cov nyom hauv tus menyuam thiab tsis tas yuav tsum tsis tsum txog kev pub niam mis rau menyuam noj. Txawm li cas los xij, yog tias koj xav tau kev siv tshuaj ntev hauv lub sijhawm lossis teem sijhawm ntau dua, yuav tsum pub mis niam rau menyuam noj kom sai.
Yeeb tshuaj sib cuam tshuam
Nrog rau kev siv acetylsalicylic acid tib lub sij hawm txhim kho qhov kev txiav txim ntawm cov tshuaj hauv qab no:
- methotrexate los ntawm kev txo kev ua kom lub raum thiab tshem nws los ntawm kev sib txuas lus nrog cov protein,
- heparin thiab tua cov kab mob tsis ncaj vim qhov ua haujlwm ntawm cov ntshav platelet thiab hloov chaw ntawm anticoagulants tsis ncaj los ntawm kev sib txuas lus nrog cov protein,
- thrombolytic thiab tshuaj antiplatelet (ticlopidine),
- digoxin vim muaj kev txo qis hauv nws lub raum kev ua haujlwm,
- cov kab mob hypoglycemic (insulin thiab sulfonylurea derivatives) vim muaj cov khoom hypoglycemic ntawm acetylsalicylic acid nws tus kheej hauv qib siab thiab hloov chaw ntawm sulfonylurea derivatives los ntawm kev sib txuas lus nrog cov protein,
- valproic acid vim nws qhov kev hloov chaw ntawm qhov sib txuas lus nrog cov protein.
Ntxiv cov nyhuv yog pom thaum noj cov tshuaj acetylsalicylic acid nrog ethanol.
Acetylsalicylic acid ua rau tsis muaj zog ntawm cov tshuaj uricosuric (benzbromarone) vim kev sib tw tubular tshem tawm uric acid.
Los txhim kho qhov kev tshem tawm cov salicylates, corticosteroids kom tsis muaj zog.
VERTEX AO (Russia)
199106 St. Petersburg Aspikard (BORISOVA COJ LOS NTAWM KEV KHO TSHUAJ TSHUAJ, Tshuaj koom pheej ntawm Belarus) Aspinat ® (VALENTA PHARMACEUTICS, Russia) Aspinat ® Cardio (VALENTA PHARMACEUTICS, Russia) Cov tshuaj aspirin ® Cardio (BAYER CONSUMER CARE, Switzerland) Acetylcardio-LekT (HOM TSHUAJ NTAU TSHUAJ - PHAJ HWJ HUAM TSWJ, Tebchaws Russia) Tso tawm daim ntawv thiab muaj pes tsawg leegAspicore yog tsim nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj enteric-coated: yuav luag dawb lossis dawb, biconvex, puag ncig, hauv ntu ntu - homogeneous loj ntawm yuav luag dawb lossis dawb (10 pcs. Hauv cov hlwv pob, hauv ib daim ntawv cardboard 1, 2, 3 lossis 6 ntim, 15 pcs .Txhua hauv cov hlwv ntim, hauv ib pob ntawv thawv 2 lossis 4 pob, 20 pcs. Hauv cov hlwv ntim, hauv ib pob ntawv thawv 1 lossis 3 pob, 30 pcs. ) Composition 1 ntsiav tshuaj:
Tsuas tshuaj thiab tswj hwmAspikor noj ntawm qhov ncauj, ua ntej noj mov, ntsiav tshuaj yuav tsum tau muab ntxuav nrog kua dej kom ntau. Cov tshuaj yog npaj rau kev siv mus sij hawm ntev, hauv chav kawm tau teeb tsa ib leeg zuj zus los ntawm tus kws kho mob tuaj koom. Hauv kev kho mob ntawm qhov tsis hnov mob angina, Aspicor siv 1-3 ntsiav tshuaj (100-300 mg) ib hnub. Txhawm rau tiv thaiv cov tshuaj raug pom zoo kom raug noj nyob rau hauv cov koob tshuaj txhua hnub:
Aspicore, cov lus qhia rau kev siv: txoj kev thiab ntau npaum li casCov tshuaj Aspicore yuav tsum noj ua ntej noj mov, muaj dej ntau. Pom zoo koob tshuaj txhua hnub:
Aspikor yog npaj rau kev kho mob mus ntev, lub sijhawm uas txiav txim los ntawm tus kws kho mob uas tuaj koom. Cev xeeb tub thiab lactation
Aspicore: tus nqi hauv cov khw muag tshuaj onlineAspicore 100 mg enteric-coated ntsiav tshuaj 30 pcs. ASPICOR 100mg 30 pcs. enteric coated ntsiav tshuaj Aspicor Tab. .p / o zaj duab xis. enteric. 100mg n30 ASPICOR 100mg 90 pcs. enteric coated ntsiav tshuaj Aspicor Tab. n / a ksh / sol. 100mg No. 90 Aspicore 100 mg enteric-coated ntsiav tshuaj 90 pcs.
Kev Kawm Ntawv: Thawj Moscow State Medical University muaj npe tom qab I.M. Sechenov, tshwj xeeb "Tshuaj General". Cov ntaub ntawv hais txog cov tshuaj raug muab dav dav, muab rau kev qhia tawm thiab tsis hloov chaw cov lus qhia. Kev siv tshuaj rau tus kheej yog qhov txaus ntshai rau kev noj qab haus huv! Kev ua haujlwm uas ib tus neeg tsis nyiam yuav muaj kev phom sij rau nws lub siab ntau dua li qhov uas tsis muaj haujlwm hlo li. Raws li kev tshawb fawb, cov poj niam uas haus ob peb khob npias lossis cawv txiv hmab ib lim tiam muaj feem ntau yuav muaj mob khees xaws mis. Muaj 74 xyoo nyob hauv tebchaws Australian yawg James Harrison tau los ua neeg muab ntshav li 1,000 zaus. Nws muaj ib hom ntshav uas tsis tshua muaj, cov tshuaj tiv thaiv uas pab cov menyuam mos liab uas muaj ntshav tsawg txaus kom ciaj sia taus. Yog li, Australian thiaj cawm tau ntau txog ob lab tus menyuam. Raws li ntau tus kws tshawb fawb, cov vitamins complex yog qhov tsis muaj txiaj ntsig rau tib neeg. Thaum txham, peb lub cev ua haujlwm tsis tiav. Txawm lub plawv nres. Thaum lub neej, tus neeg nruab nrab tsim tawm tsis tsawg tshaj li ob lub pas dej loj uas muaj qaub ncaug. Nws tau siv los ua yawning enriches lub cev nrog oxygen. Txawm li cas los xij, qhov kev pom no tau nthuav dav. Cov kws tshawb fawb tau ua pov thawj tias yawning, ib tus neeg ua kom lub hlwb txias thiab txhim kho kev ua haujlwm. Thaum lub sijhawm ua haujlwm, peb lub hlwb siv ntau npaum li cas ntawm lub zog sib npaug rau 10-watt lub teeb lub teeb. Yog li cov duab ntawm lub teeb txawb saum koj lub taub hau thaum lub sijhawm pom ntawm qhov kev xav zoo nkauj tsis deb ntawm qhov tseeb. Yog tias koj poob los ntawm tus nees luav, koj nyiam yob koj lub caj dab ntau dua li yog koj ntog los ntawm nees. Tsuas tsis sim rau refute nqe lus no. Hauv kev mob siab kom tau tus neeg mob tawm, cov kws kho mob feem ntau mus deb dhau. Yog li, piv txwv li, qee yam Charles Jensen nyob rau lub sijhawm txij xyoo 1954 txog 1994. muaj sia nyob ntau dua 900 lub neoplasm tshem tawm txoj haujlwm. Tus neeg noj tshuaj tiv thaiv kab mob feem ntau yuav rov qab muaj kev nyuaj siab. Yog tias ib tug neeg mob nrog kev nyuaj siab ntawm nws tus kheej, nws muaj txhua lub sijhawm tsis nco qab txog lub xeev no tas mus li. Txawm hais tias ib tug neeg lub siab tsis yeej, tam sim no nws tseem tuaj yeem nyob rau lub sijhawm ntev, zoo li tus neeg nuv ntses neeg Norwegian Jan Revsdal tau ua rau peb pom. Nws "lub cev muaj zog" nres rau 4 xuab moos tom qab tus neeg nuv ntses tau ploj thiab tsaug zog hauv cov daus. Ntau cov tshuaj tau xub pib ua lag luam li tshuaj. Piv txwv li yeeb dawb, tau pib ua lag luam ua tshuaj hnoos. Thiab cocaine tau pom zoo los ntawm cov kws kho mob ua tshuaj loog thiab yog lub zog ntawm kev ua kom lub siab ntev. Qhov kub siab tshaj plaws ntawm lub cev tau sau cia ntawm Willie Jones (USA), uas tau nkag rau hauv tsev kho mob nrog qhov kub txog 46,5 ° C. Lub siab yog qhov ua haujlwm hnyav tshaj plaws hauv peb lub cev. Nws qhov hnyav nruab nrab yog 1.5 kg. Cov roj ntses tau paub txog ntau xyoo lawm, thiab lub sijhawm no nws tau muaj pov thawj tias nws pab txo kev mob, txo kev mob sib koom tes, txhim kho sos.
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