Kev qhia rau kev siv thiab cov lus qhia rau kev siv tshuaj Dibikor

Npe sau npe: P N001698 / 01
Pauv lub npe ntawm qhov kev npaj: Dibicor®
Lub npe thoob ntiaj teb nonproprietary: taurine
Dosage daim ntawv: ntsiav tshuaj
Muaj pes tsawg leeg: 1 ntsiav tshuaj muaj:
cov tshuaj nquag:

• taurine 250 mg
  tus muaj mob: microcrystalline cellulose 23 mg,
  qos yaj ywm hmoov txhuv nplej 18 mg, gelatin 6 mg, colloidal silicon dioxide
  (aerosil) 0.3 mg; calcium stearate 2.7 mg.
• taurine 500 mg
  tus muaj mob: microcrystalline cellulose 46 mg,
  qos yaj ywm hmoov nplej 36 mg, gelatin 12 mg, colloidal silicon dioxide
  (aerosil) 0.6 mg; calcium stearate 5.4 mg.

Kev piav qhia: ntsiav tshuaj ntawm cov xim dawb lossis yuav luag xim dawb, puag ncig, tiaj-cylindrical, nrog kev pheej hmoo thiab lub ntsej muag.
Pharmacotherapeutic pab pawg: tus neeg sawv cev metabolism.
ATX Code: C01EB

PHARMACOLOGICAL COV CAI

Cov Tshuaj Hauv Tshuaj
Taurine yog cov khoom ntuj tsim ntawm kev hloov pauv ntawm leej faj-muaj cov amino acids: cysteine, cysteamine, methionine. Taurine muaj osmoregulatory thiab membrane-tiv thaiv cov yam ntxwv, muaj qhov cuam tshuam zoo phospholipid muaj pes tsawg leeg ntawm cov qog ua cell, thiab normalizes pauv ntawm calcium thiab potassium ions hauv hlwb. Taurine muaj cov khoom ntawm inhibitory neurotransmitter, nws muaj cov nyhuv antistress, tuaj yeem tswj kev tso tawm ntawm gamma-aminobutyric acid (GABA), adrenaline, prolactin thiab lwm cov tshuaj hormones, ntxiv rau kev tswj hwm cov lus teb rau lawv. Koom nrog kev sib txuas ntawm cov pa ua pa nyob rau hauv mitochondria, taurine tswj cov txheej txheem oxidative thiab pov thawj cov khoom antioxidant, cuam tshuam rau cov enzymes xws li cytochromes koom nrog cov metabolism hauv ntau xenobiotics.

Kev kho mob Dibicor for rau cov kev mob plawv tsis txaus (CCH) ua rau txo qis ntawm txoj hlab ntsws thiab txoj hlab ntshav: kev mob hauv lub plawv tsis txaus, qhov kev cog lus myocardial nce ntxiv (qhov siab tshaj plaws ntawm kev txo qis thiab so, kev sib cog lus thiab so kom txaus).

Cov tshuaj muaj pes tsawg leeg txo cov ntshav siab (BP) hauv cov neeg mob ntshav siab thiab tsis cuam tshuam txog ntshav siab hauv cov neeg mob plawv tsis txaus, tsis muaj ntshav siab. Dibicor® txo cov kev phiv uas tshwm sim nrog kev noj tshuaj ntau dhau ntawm lub plawv glycosides thiab "qeeb" calcium channel blockers, thiab txo qis hepatotoxicity ntawm cov tshuaj tua kab mob. Ntxiv kev ua tau zoo thaum kev tawm dag zog lub cev.

Hauv cov ntshav qab zib mellitus, kwv yees li 2 lub lis piam tom qab pib noj Dibicor®, cov ntsiab lus ntawm cov piam thaj hauv cov ntshav txo qis. Ib qho kev txo qis tseem ceeb hauv cov concentration ntawm triglycerides, rau qhov tsawg dua, qhov kev nce siab ntawm cov roj cholesterol, qhov txo qis hauv atherogenicity ntawm ntshav lipids, kuj tau pom. Nrog kev siv tshuaj ntev (li 6 lub hlis)
txhim kho microcirculatory ntshav ntws hauv qhov muag.

Cov Tshuaj Pharmacokinetics
Tom qab txhaj ib koob tshuaj 500 mg ntawm Dibicor, cov tshuaj taurine nquag hauv 15-20 feeb yog txiav txim siab hauv cov ntshav,
mus txog qhov siab kawg tom qab 1.5-2 teev. Cov tshuaj no ua tiav tawm hauv ib hnub.

Kev taw qhia rau kev siv:

• hlab plawv tsis ua haujlwm ntawm ntau etiologies,
• mob glycoside intoxication,
• ntshav qab zib hom 1
• yam 2 mob ntshav qab zib mellitus, suav nrog kev tuaj yeem tiv thaiv kab mob ntshav siab,
• raws li hepatoprotector hauv cov neeg mob noj tshuaj tiv thaiv kab mob.

Tso tawm daim ntawv thiab muaj pes tsawg leeg

Muaj nyob rau hauv cov ntsiav tshuaj: tiaj-cylindrical, dawb lossis yuav luag dawb, nrog kev pheej hmoo thiab lub ntsej muag (250 mg txhua hauv 10 ntim hauv cov hlwv pob, nyob rau hauv ib pob ntawm cardboard 3 lossis 6 pob, 30 lossis 60 tej daim hauv lub khob dub, hauv ntim ntawm cov duab los qhia 1 tuaj yeem, 500 mg - 10 daim ib qho hauv pob tau ntim cov hlwv ntim, hauv pob ntawv ntawm pob ntawv los yog 3 lossis 6 pob).

Cov khoom siv nquag: taurine, hauv 1 ntsiav tshuaj - 250 lossis 500 mg.

Ntu cov khoom siv: cov hmoov txhuv nplej siab, microcrystalline cellulose, calcium stearate, colloidal silicon dioxide (aerosil), gelatin.

Cov Tshuaj Hauv Tshuaj

Taurine - cov tshuaj nquag ntawm Dibikor - cov khoom ntuj tsim ntawm kev sib pauv ntawm leej faj-muaj cov amino acids: cysteamine, cysteine, methionine. Nws muaj osmoregulatory thiab membrane tiv thaiv kev ua haujlwm, muaj cov txiaj ntsig zoo ntawm phospholipid muaj pes tsawg leeg ntawm cov qog ntawm tes, thiab pab ua kom cov kev hloov pauv ntawm cov potassium thiab calcium ions hauv hlwb.

Nws muaj cov yam ntxwv ntawm kev tiv thaiv neurotransmitter, muaj cov tshuaj antioxidant thiab antistress, tswj kev tso tawm GABA (gamma-aminobutyric acid), prolactin, adrenaline thiab lwm cov tshuaj hormones, ntxiv rau cov lus teb rau lawv. Nws koom nrog kev sib txuas ntawm cov pa ua pa nyob rau hauv mitochondria, tsim nyog rau cov txheej txheem oxidative, thiab cuam tshuam cov enzymes lub luag haujlwm rau cov metabolism ntawm ntau xenobiotics.

Hauv cov neeg mob ntshav qab zib, kwv yees li 2 lub lis piam tom qab pib kho, kev pom nyob rau hauv cov ntshav qabzib tsawg dua. Kuj tseem muaj qhov kev txo qis tseem ceeb nyob rau hauv cov concentration ntawm triglycerides, rau qee qhov qis me ntsis - atherogenicity ntawm ntshav lipids, cov qib roj cholesterol. Thaum lub sijhawm kawm ntev (li rau lub hlis), muaj kev txhim kho ntawm microcirculatory ntshav ntawm lub qhov muag pom.

Lwm cov teebmeem ntawm Dibikor:

• kev txhim kho ntawm cov txheej txheem hauv cov zaub mov hauv lub siab, lub siab thiab lwm yam nqaij thiab kabmob,
• nce ntshav txaus thiab txo qis heev cytolysis nyob rau hauv lub xub ntiag ntawm mob ntev daim siab mob siab,
• txo qis ntawm kev daig hauv lub voj voog me / loj ntawm cov ntshav ncig nrog lub plawv tsis ua haujlwm, uas tshwm sim nws tus kheej ntawm daim ntawv poob qis ntawm intracardiac diastolic siab, nce myocardial contractility,
• txo qis hauv hepatotoxicity ntawm cov tshuaj tua kabmob nrog kev siv tag nrho,
• txo qis hauv cov ntshav siab nrog cov hlab ntsha txhaws, thaum nyob rau hauv cov neeg mob mob plawv tsis txaus ntawm cov ntshav siab, cov nyhuv no tsis tuaj,
• txo qis hauv qhov hnyav ntawm qhov tshwm sim tsis zoo tshwm sim los ntawm kev noj ntau dhau ntawm cov mob glycosides thiab qeeb calcium channel blockers,
• kev ua tau zoo dua thaum ua lub cev hnyav dhau los.

Cov lus qhia rau kev siv Dibikora: txoj kev thiab ntau npaum li cas

Dibicor yuav tsum tau noj qhov ncauj.

Pom zoo txog kev kho mob nyob ntawm qhov ntsuas:

• Lub plawv tsis ua haujlwm: 250-500 mg 2 zaug hauv ib hnub 20 feeb ua ntej noj mov, lub sijhawm kho yog tsawg kawg 30 hnub. Yog tias tsim nyog, koob tshuaj txhua hnub yog nce mus rau 2000-3000 mg,
• Mob glycoside intoxication: tsawg kawg 750 mg ib hnub twg,
• Yam 1 ntshav qab zib mellitus: 500 mg 2 zaug ib hnub nyob rau hauv kev sib xyaw nrog insulin. Lub sij hawm ntawm kev kho mob yog 3-6 lub hlis,
• Yam 2 ntshav qab zib mellitus: 500 mg 2 zaug hauv ib hnub los ua ib yam tshuaj lossis ua ke nrog lwm cov tshuaj tiv thaiv kab mob ntshav qab zib,
• Raws li cov tshuaj hepatoprotective: 500 mg 2 zaug ib hnub rau tag nrho lub sijhawm ntawm kev siv tshuaj tua kab mob.

Yeeb tshuaj sib cuam tshuam

Taurine ua rau kev ua rau inotropic muaj txiaj ntsig ntawm mob glycosides.

Yog tias tsim nyog, Dibicor tuaj yeem siv nrog lwm cov tshuaj.

Dibikor cov duab ntxiv yog: Taufon, ATP-ntev, Tauforin OZ, Tincture ntawm hawthorn, ATP-Forte, Vazonat, Ivab-5, Kapikor, Karduktal, Cardioactive Taurin, Mexico, Metamax, Metonat, Mildrocard, Milkardin, Neocardilok, Rimodokib, Rimodokib, Rimodokib , Tricard, Trizipin, Trimet, Vazopro, Mildrazin, Mildronat.

Kev Ntsuam Xyuas Ntawm Chaw Sib Tham

Raws li kev txheeb xyuas, Dibikor yog qhov khoom siv pheej yig thiab ua tau zoo. Lawv qhia tias cov tshuaj muaj kam rau ua tau zoo, sai qab zib cov suab thaj, pab txhawb kev ua haujlwm zoo, txhim kho kev nco thiab zoo. Qee tus neeg mob tsis txaus siab txog cov ntsiav tshuaj loj, uas ua rau lawv nqos nyuaj.

Tsuas tshuaj thiab tswj hwm

Dibicor cov ntsiav tshuaj noj ntawm qhov ncauj ua ntej noj mov (feem ntau 20 feeb ua ntej noj mov). Lawv yuav tsum tau noj tag nrho yam tsis ntxo thiab haus dej ntau. Qhov ntau npaum ntawm cov tshuaj yog nyob ntawm cov txheej txheem pathological hauv lub cev:

• Lub plawv tsis ua haujlwm - 250 lossis 500 mg 2 zaug hauv ib hnub, yog tias tsim nyog, ntau npaum li cas ntxiv tau ntxiv rau 1-2 g (1000-2000 mg) hauv ob peb koob tshuaj. Lub sijhawm ntawm kev kho mob yog txiav txim siab los ntawm cov tsos mob ntawm lub siab, ntawm qhov nruab nrab, nws yog 30 hnub.
• Yam 1 mob ntshav qab zib mellitus (insulin-dependant) - cov ntsiav tshuaj tau noj nrog qhov sib xyaw tsim nyog ntawm kev kho tshuaj insulin ntawm kev noj tshuaj ntau npaum li 500 mg 2 zaug hauv ib hnub, kev ncua sijhawm kho yog los ntawm 3 hlis txog rau lub hlis.
• Yam 2 ntshav qab zib mellitus (non-insulin-dependant) - 500 mg 2 zaug hauv ib hnub raws li kev kho mob monotherapy lossis hauv kev sib xyaw nrog lwm cov tshuaj uas muaj suab thaj. Hauv tib lub koob tshuaj, Dibicor ntsiav tshuaj yog siv rau cov ntshav qab zib nrog cov ntshav nce siab ntau (hypercholesterolemia). Lub sijhawm sijhawm ntawm kev kho yog txiav txim los ntawm tus kws kho mob ntawm tus kheej, nyob ntawm kev kuaj sim ntawm carbohydrate thiab lipid metabolism.
• Mob glycoside ua rau qaug - 750 mg ib hnub twg rau 2-3 koob.
• Kev tiv thaiv kab mob rau tshuaj lom neeg lub siab thaum siv cov tshuaj tiv thaiv kev ua txhaum - 500 mg 2 zaug hauv ib hnub nyob thoob plaws hauv lawv lub sijhawm tswj hwm.

Feem ntau, sijhawm kawm ntawm kev kho nrog cov tshuaj no yog txiav txim los ntawm tus kws kho mob ib tus zuj zus.

Sab sij huam

Feem ntau, Dibicor ntsiav tshuaj muaj kev tiv thaiv zoo. Qee lub sij hawm nws muaj peev xwm tsim kev tawm tsam nrog kev tshwm sim ntawm daim tawv nqaij ua pob, ua pob khaus lossis khaus (ua pob xoo nrog o uas zoo li mob nettle hlawv). Cov kev txhaum fab hnyav (angioedema Quincke edema, anaphylactic shock) tom qab siv cov tshuaj tsis tau piav qhia.

Cov lus qhia tshwj xeeb

Rau cov ntsiav tshuaj Dibicor, muaj ntau cov lus qhia tshwj xeeb uas koj yuav tsum them sai sai ua ntej pib siv:

• Tawm tsam cov keeb kwm yav dhau los ntawm kev sib faib nrog cov mob glycosides lossis calcium channel blockers, kev noj cov tshuaj Dibicor yuav tsum tau txo tsawg dua li 2 zaug, nyob ntawm seb tus neeg mob rhiab heev rau cov tshuaj no.
• Cov tshuaj tuaj yeem siv nrog rau cov tshuaj ntawm lwm pab pawg pharmacological.
• Tsis muaj cov ntaub ntawv qhia txog kev nyab xeeb ntawm cov ntsiav tshuaj Dibicor hauv kev sib raug zoo ntawm kev txhim kho menyuam hauv plab thaum cev xeeb tub lossis tus menyuam mos thaum lub sijhawm pub niam mis, yog li ntawd, hauv cov xwm txheej no, lawv kev tswj hwm tsis pom zoo.
• Cov tshuaj tsis cuam tshuam rau kev ceev ntawm psychomotor cov tshuaj tiv thaiv lossis qhov tseem cia siab.

Hauv cov tsev muag tshuaj, cov tshuaj tau faib tawm yam tsis muaj daim ntawv yuav tshuaj. Yog tias muaj kev ua xyem xyav lossis nug txog kev siv Dibicor ntsiav tshuaj, sab laj nrog koj tus kws kho mob.

Cov Yuav Tsum Muaj

Hypersensitivity rau cov tshuaj. Tsis txog 18 xyoo
(kev ua tau zoo thiab kev nyab xeeb tsis tau tsim).
Siv thaum cev xeeb tub thiab thaum pub niam mis
Nws tsis raug nquahu kom siv cov tshuaj thaum cev xeeb tub thiab thaum xeeb menyuam
kev pub niam mis vim tias tsis muaj kev txheeb xyuas pom
daim ntawv thov nyob rau hauv pawg no ntawm cov neeg mob.