Ultrashort insulin Humalog, NovoRapid thiab Apidra

Tib neeg lub cev luv luv pib ua 30-45 feeb tom qab txhaj, thiab qhov tseeb tshaj plaws hom insulin Humalog, NovoRapid thiab Apidra - txawm tias nrawm dua, tom qab 10-15 feeb. Humalog, NovoRapid thiab Apidra tsis yog tib neeg cov insulin, tab sis analogues, uas yog, hloov kho, hloov kho dua piv rau "insulin" tib neeg. Ua tsaug rau lawv cov mis hloov pauv, lawv pib txo cov ntshav qab zib kom nrawm dua tom qab lawv nkag rau hauv lub cev.

Ultrashort insulin analogues tau tsim kho sai sai txwv ntshav qab zib kom ntshav uas muaj tshwm sim thaum uas tus mob ntshav qab zib xav noj cov khoom noj sai sai. Hmoov tsis zoo, cov tswv yim no tsis ua haujlwm hauv kev xyaum, vim tias cov piam thaj dhia los ntawm cov suab thaj zoo li npau taws. Nrog rau kev nkag mus rau kev lag luam ntawm Humalog, NovoRapid thiab Apidra, peb tseem tseem ua raws li kev ua lag luam. Peb siv ultrashort analogues ntawm cov kua dej kom sai sai cov piam thaj kom ib txwm muaj yog nws dhia dhia, thiab qee zaus hauv cov xwm txheej tshwj xeeb ua ntej noj mov, thaum nws tsis xis nyob tos 40-45 feeb ua ntej noj mov.

Kev hno ntshav ntawm luv luv lossis ultrashort insulin ua ntej noj mov yog xav tau rau cov neeg mob ntshav qab zib hom 1 lossis hom 2, uas muaj ntshav qab zib cov ntshav tom qab noj mov. Nws tau kwv yees tias koj twb tau ua raws li cov zaub mov tsis muaj roj ntau ntau, thiab kuj tau sim, tab sis tag nrho cov kev ntsuas no pab tsuas yog qee. Kawm thiab. Cov neeg mob uas muaj ntshav qab zib hom 2, raws li txoj cai, nws ua rau kev nkag siab tau ua ntej sim kho tsuas yog siv tshuaj insulin ntev, raws li tau piav nyob hauv kab lus “”. Tej zaum koj lub txiav los ntawm insulin ntev li so zoo thiab perks tias nws tuaj yeem tua nws tus kheej hauv cov ntshav qab zib tom qab noj mov, tsis tas yuav ntxiv cov tshuaj insulin ua ntej noj mov.

Yuav kho cov ntshav qab zib li cas nrog cov insulin luv luv lossis ultra-luv

Ultrashort insulin pib ua ua ntej lub cev muaj sijhawm los nqus cov protein thiab tig qee qhov ua qabzib. Yog li, yog tias koj soj ntsuam, tom qab ntawd ua ntej noj insulin luv luv zoo dua li Humalog, NovoRapid lossis Apidra. Cov tshuaj insulin luv luv yuav tsum tau siv sijhawm li 45 feeb ua ntej noj mov. Nov yog lub sijhawm kwv yees, thiab txhua tus neeg mob ntshav qab zib yuav tsum qhia meej nws tus kheej rau nws tus kheej. Yuav ua li cas ua nws, nyeem. Qhov kev txiav txim siab ntawm hom insulin ceev kav ntev li 5 teev. Nov yog lub sijhawm uas tib neeg ib txwm yuav tsum tau zom cov pluas mov uas lawv tau noj.

Peb siv cov tshuaj insulin nyob rau hauv "thaum muaj xwm txheej ceev" kom txo qis cov ntshav qab zib kom nws li qub yog tias nws dhia dheev. Teeb meem ntawm ntshav qab zib loj hlob tuaj thaum uas cov ntshav qab zib kom nws nyob hauv siab. Yog li no, peb sim ua kom nws qis dua qub kom sai li sai tau, thiab rau cov kab mob ultra-luv luv no zoo dua li luv. Yog tias koj muaj ntshav qab zib hom 2 me me, uas yog, nce cov piam thaj sai sai rau nws tus kheej, tom qab ntawd koj tsis tas yuav hno cov tshuaj insulin ntxiv kom tsawg. To taub txog ntshav qab zib cov ntshav ua li cas nyob hauv tus neeg mob ntshav qab zib tsuas pab tau ob peb hnub uake.

Ultra-luv hom insulin - ua sai dua txhua tus

Ultrashort hom insulin yog Humalog (Lizpro), NovoRapid (Aspart) thiab Apidra (Glulizin). Lawv tau tsim los ntawm peb lub tuam txhab tshuaj sib txawv uas cov neeg sib tw nrog ib leeg. Cov tshuaj insulin luv luv yog tib neeg, thiab ultrashort yog cov qauv, piv txwv li, hloov kho, txhim kho, piv nrog insulin tib neeg tiag. Qhov kev txhim kho yog qhov tseeb uas lawv pib txo cov ntshav qab zib kom nrawm dua li cov luv luv ib txwm - 5-15 feeb tom qab txhaj.

Ultrashort insulin analogues tau tsim kom qeeb cov piam thaj hauv ntshav thaum muaj ntshav qab zib xav noj cov zaub mov sai.Hmoov tsis zoo, lub tswv yim no tsis ua haujlwm rau hauv kev xyaum. Carbohydrates, uas tam sim ntawd nqus, tseem nce ntshav qab zib sai dua txawm tias qhov tseeb tshaj tawm luv luv insulin tswj kom nws tsawg dua. Nrog kev pib ua cov insulin tshiab no ntawm kev ua lag luam, tsis muaj leej twg tau tshem tawm qhov kev xav tau ua raws thiab ua raws. Yog lawm, koj yuav tsum tau ua raws li kev tswj hwm tsuas yog koj xav kom tswj tau ntshav qab zib kom zoo thiab zam rau nws cov teeb meem.

Yog tias koj ua raws li cov zaub mov uas tsis muaj carbohydrate tsawg rau cov ntshav qab zib hom 1 lossis hom 2, tom qab ntawd cov tshuaj insulin luv luv yog qhov zoo dua rau kev txhaj tshuaj ua ntej noj mov dua li ultra-short counterparts. Vim hais tias nyob rau hauv cov neeg mob ntshav qab zib uas haus me ntsis carbohydrates, lub cev thawj zaug zom cov protein, thiab tom qab ntawd hloov qee qhov ntawm nws mus rau hauv qabzib. Qhov no yog tus txheej txheem qeeb, thiab cov tshuaj insulin ultrashort pib ua haujlwm sai dhau. Luv luv hom insulin - txoj cai. Lawv feem ntau yuav tsum tau pricked 40-45 feeb ua ntej cov zaub mov muaj cov carbohydrate tsawg.

Txawm li cas los xij, rau cov neeg mob ntshav qab zib uas txwv tsis pub muaj carbohydrates hauv lawv cov pluas noj, cov tshuaj insulin ultrashort tuaj yeem tuaj yeem ua ke. Yog tias koj ntsuas koj qab zib nrog glucometer thiab pom tias nws dhia, tom qab ntawd cov insulin ultra-luv yuav txo qis dua sai dua li luv. Qhov no txhais tau tias cov mob ntshav qab zib yuav muaj sijhawm tsawg los tsim. Koj tuaj yeem tso cov tshuaj insulin ultrashort, yog tias koj tsis muaj sijhawm tos 45 feeb ua ntej koj pib noj mov. Qhov no yog qhov tsim nyog hauv tsev noj mov lossis hauv kev ncig xyuas.

Saib xyuas! Cov tshuaj insulins yog ntau dua cov haib dua li cov luv luv. Tshwj xeeb, 1 Chav ntawm Humaloga yuav txo qis ntshav qab zib li ntawm 2,5 zaug ntau dua 1 Unit ntawm insulin luv. NovoRapid thiab Apidra yog kwv yees 1.5 zaug zoo dua li cov insulin luv. Qhov no yog kwv yees sib piv, thiab rau txhua tus neeg mob ntshav qab zib yuav tsum tsim nws rau nws tus kheej los ntawm kev sim thiab kev ua yuam kev. Raws li, koob tshuaj ntawm ultrashort insulin analogs yuav tsum muaj ntau qis dua qhov sib npaug ntawm cov tshuaj tiv thaiv luv luv ntawm tib neeg cov insulin. Kuj, kev sim tau pom tias Humalog pib ua 5 feeb sai dua ntawm NovoRapid thiab Apidra.

Qhov zoo thiab qhov tsis zoo ntawm ultrashort insulin

Piv nrog rau hom kab mob ntshav qis rau tib neeg, hom tshiab ntawm cov kab mob insulin muaj qhov zoo thiab qhov tsis zoo. Lawv tau ua tiav kawg ntawm kev txiav txim siab, tab sis tom qab ntawd lawv cov ntshav theem qis qis dua yog tias koj txhaj nrog insulin luv luv. Txij thaum cov tshuaj insulin muaj qhov muag siab, nws yog qhov nyuaj rau kwv yees ntau npaum li cas cov zaub mov carbohydrates koj yuav tsum tau noj nyob rau hauv kev txiav txim rau cov ntshav qab zib kom tsis txaus. Qhov kev coj ua ntawm insulin luv luv yog zoo dua qub nrog kev ua kom yoo ntawm cov khoom noj los ntawm lub cev, yog tias pom.

Ntawm qhov tod tes, ib qho kev txhaj tshuaj ntawm cov insulin luv luv yuav tsum tau ua 40-45 feeb ua ntej noj mov. Yog tias koj pib noj zaub mov sai dua, tom qab ntawd cov tshuaj insulin luv luv yuav tsis muaj sijhawm los ua, thiab cov ntshav qab zib yuav dhia. Tshiab hom kab mob insulin pib ua ntau yam nrawm dua, tsis pub dhau 10-15 feeb tom qab txhaj tshuaj. Qhov no yooj yim heev yog tias koj tsis paub xyov lub sijhawm yuav noj pib noj dab tsi. Piv txwv li, thaum koj nyob hauv tsev noj mov. Yog tias koj ua raws, peb pom zoo kom koj siv luv luv cov tshuaj insulin ua ntej noj mov hauv ib qho xwm txheej. Tsis tas li ntawd khaws insulin ultra-luv npaj rau lub sijhawm tshwj xeeb.

Kev xyaum qhia tau hais tias ultrashort hom insulin cuam tshuam rau cov ntshav qab zib kom tsawg dua li cov luv. Lawv ua tsis tau kwv yees, txawm hais tias lawv tau txhaj rau hauv koob tshuaj me, raws li cov neeg mob ntshav qab zib tau ua, ua raws li cov zaub mov uas tsis muaj carbohydrate, thiab tseem muaj ntau dua yog tias lawv tau txhaj ntau dua. Tseem nco ntsoov tias ultrashort hom insulin muaj hwj chim ntau dua li cov luv. 1 ntu ntawm Humaloga yuav txo cov ntshav qab zib kom tsawg li 2.5 npaug muaj zog dua 1 ntu ntawm luv luv insulin. NovoRapid thiab Apidra yog kwv yees li 1.5 npaug zog dua li cov insulin luv.Raws li, qhov koob tshuaj ntawm Humalog yuav tsum yog kwv yees li 0.4 koob tshuaj insulin luv, thiab koob tshuaj NovoRapid lossis Apidra - txog ⅔ koob tshuaj. Nov yog cov lus qhia uas koj xav tau kom meej rau koj tus kheej los ntawm kev sim.

Peb lub hom phiaj tseem ceeb yog txo qis los yog tiv thaiv kom tsis txhob dhia hauv ntshav qab zib tom qab noj mov. Yuav kom ua tiav qhov no, koj yuav tsum tau txhaj tshuaj ua ntej noj mov nrog lub sijhawm txaus rau insulin pib ua yeeb yam. Ntawm ib sab tes, peb xav kom insulin pib txo qis cov ntshav qab zib thaum lub zom zaub mov pib pib nce nws. Ntawm qhov tod tes, yog tias koj txhaj tshuaj insulin ntxov dhau, koj cov piam thaj hauv ntshav yuav poob sai dua li cov zaub mov tuaj yeem nqa tau. Kev xyaum qhia tau tias nws yog qhov zoo tshaj rau kev nqus cov tshuaj insulin luv luv 40-45 feeb ua ntej pib noj zaub mov kom tsawg. Muaj kev zam tshwj xeeb yog cov neeg mob uas tau tsim muaj ntshav qab zib lub plab zom mov, i.e., ncua sij hawm nchuav ntawm lub plab tom qab noj mov

Tsis tshua muaj, tab sis tseem tuaj hla cov neeg mob ntshav qab zib, nyob rau hauv uas luv luv hom tshuaj insulin rau qee qhov laj thawj yog nqus mus rau hauv cov hlab ntshav tshwj xeeb tshaj yog qeeb. Lawv yuav tsum tau txhaj cov insulin ntawd, piv txwv li, 1.5 teev ua ntej noj mov. Yog lawm, qhov no tsis yooj yim heev. Lawv yuav tsum siv cov khoom siv tshiab tshaj tawm ntawm cov kua dej (insulin analogs) ua ntej noj mov, qhov nrawm tshaj plaws uas yog Humalog. Peb taw qhia ib zaug ntxiv tias cov neeg mob ntshav qab zib yog yam tsis tshua pom muaj tshwm sim.

Kev txuas ntxiv ntawm tsab xov xwm koj nyuam qhuav nyeem yog “nplooj ntawv”.

Nws yog suav hais tias yog ib txoj hauv kev ua rau kev kho mob ntshav qab zib mellitus vim qhov tseeb tias nws tso cai rau koj kom ua tiav cov txiaj ntsig zoo tshaj plaws hauv kev ua kom lub neej tag nrho, ua kom ntev nws lub sijhawm thiab tiv thaiv kev pheej hmoo ntawm cov teeb meem.

Qhia txog Insulin yog:

• Txog kev kho mob ntshav qab zib hom 1,
• Raws li kev tiv thaiv los ua kom cov neeg mob ntshav qab zib hom 2 mob ntshav qab zib,
• Yog tias nws tsis tuaj yeem them tus nqi ntshav qab zib hom 2 nrog rau lwm txoj kev kho.

Tseem ceeb kom paub: tus kws kho mob mus koom yuav tsum xaiv qhov raug zoo ntawm tib neeg cov tshuaj insulin thiab suav qhov pib txhaj tshuaj kho.

Cov ntaub ntawv hais txog Apidra: muaj pes tsawg leeg, taw qhia thiab contraindications rau siv

Ntawm cov analogues niaj hnub ntawm tib neeg cov tshuaj insulin, xws li cov tshuaj xws li Apidra, kev ua yeeb yam luv luv, cov kab mob hypoglycemic uas pab txo qis thiab ua kom cov ntshav qab zib cov ntshav muaj zog ntawm cov neeg mob ntshav qab zib, pab txhim kho cov ntshav qabzib los ntawm peripheral cov ntaub so ntswg thiab txhawb cov ntshav qabzib los ntawm lub siab hlwb, thiab nce qib protein ntau. Qhov kev ua ntawm cov tshuaj insulin pib 10-15 feeb tom qab txhaj tshuaj, uas yog muab piv rau hauv cov khoom nrog cov tshuaj insulin los ntawm cov txiav ntshav. Nws yog qhia rau cov ntshav qab zib hom 1 thiab 2.

Cov tshuaj nquag yog cov tshuaj insulin glulisin (3.49 mg).

Cov kev zam - meta-cresol, sodium chloride, trometanol, polysorbate 20, hydrochloric acid, sodium hydroxide, dej distilled.
Cov tshuaj insulin yog qhov tseeb, tsis muaj xim kiag li.

Kev ntsuas rau siv

Tseem ceeb kom paub: Apidra tsuas yog kho rau cov neeg laus mob ntshav qab zib xwb.

• Cov neeg tsis qaug rau yeeb tshuaj lossis cov tshuaj ntawd,
• Kev ntshav siab.

Cov lus qhia rau kev siv cov tshuaj no

Cov tshuaj yog txhaj rau hauv lub xub pwg, plab los sis ncej puab, koj tuaj yeem siv tus qauv ntawm kev txuas ntxiv mus rau hauv cov nqaij fiber hauv qab daim tawv nqaij.

Raws li txoj cai, cov tshuaj insulin raug txhaj 15 feeb lossis ua ntej noj mov, thiab nws yog qhov yuav tsum tau hloov cov chaw txhaj tshuaj kom tsis txhob tsim kev pheej hmoo ntawm cov tawv nqaij cuam tshuam thiab microcracks ntawm daim tawv nqaij. Tom qab txhaj tshuaj tas lawm, koj tuaj yeem tsis zaws qhov chaw txhaj tshuaj, kom tsis txhob ua rau cov tshuaj mus rau hauv cov hlab.

Cov koob tshuaj txhaj rau txhua tus neeg mob ntshav qab zib tau xaiv ib tus zuj zus.

Nyob rau hauv cov ntaub ntawv ntawm ib tug overdose, tau tshwm sim:

Yog tias muaj daim ntawv me me ntawm cov ntshav qab zib tsawg, tom qab ntawd nws tuaj yeem nres nrawm nrog zaub mov nrog piam thaj lossis noj qabzib.Yog li ntawv, cov kws kho mob pom zoo kom txhua tus neeg mob ntshav qab zib ib txwm nqa ib qho piam thaj nrog lawv.

Hauv cov foos hnyav ntawm hypoglycemia, uas nrog nrog kev tsis nco qab, nws yog qhov yuav tsum tau txhaj tshuaj glucagon lossis qabzib intramuscularly - kev xaiv cov tshuaj yog nyob ntawm tus neeg cov yam ntxwv ntawm kev kawm mob ntshav qab zib hauv tus neeg mob.

Kev mob ntshav siab ntshav qis kuj qhia tau nws tus kheej li qhov tshwm sim hauv thawj theem ntawm kev kho. Raws li txoj cai, txhua qhov kev ua tsis zoo dhau plaws yog tus neeg mob tuaj yeem kho tau.

Kuv puas tuaj yeem siv insulin apidra thaum cev xeeb tub?

Qhov ntsuas ntawm no ntawm tib neeg cov tshuaj insulin tuaj yeem siv thaum cev xeeb tub, tab sis ua tib zoo, ua tib zoo saib xyuas qib qab zib thiab, nyob ntawm nws, kho qhov koob tshuaj ntawm lub cev. Raws li txoj cai, hauv thawj lub hlis ntawm cev xeeb tub, cov koob tshuaj tsawg zuj zus, thiab hauv zaum ob thiab thib peb, nws maj mam nce ntxiv. Tom qab yug menyuam tas, qhov xav tau ntawm koob tshuaj ntau dua ntawm Apidra ploj, yog li ntawd qhov koob tshuaj tau raug txo dua.

Cov tshuaj zoo sib cuam tshuam

Niaj hnub no, cov tshuaj no tuaj yeem hloov tau zoo.

Ua tsaug rau cov txiaj ntsig tau zoo ntawm kev kho mob nrog cov tshuaj, niaj hnub no nws yog txawm rau menyuam yaus, tab sis tsuas yog tom qab hnub nyoog muaj rau xyoo.

Niaj hnub no, cov tshuaj yuav tuaj yeem yuav hauv khw muag tshuaj hauv daim ntawv ntawm kev daws teeb meem hauv lub hwj ntawm 100 units lossis hauv cov koob txhaj tshuaj.

Koj tuaj yeem yuav lub raj mis ntawm cov tshuaj hauv Lavxias nyob rau tus nqi nruab nrab ntawm 2000 rubles, ib pawg ntawm cwj mem-rab koob (5 pcs.) - yuav raug nqi los ntawm 2100 rubles.

Hauv khw muag tshuaj ntawm Ukraine koj tuaj yeem yuav ib txheej syringe cwjmem (5 pcs.) Thaum tus nqi kwv yees 1400 UAH.

Apidra yog txoj kev them se ntawm tib neeg cov tshuaj insulin, cov khoom siv tseem ceeb yog glulisin. Qhov peculiarity ntawm cov tshuaj yog tias nws pib ua haujlwm nrawm dua li tib neeg cov tshuaj insulin, tab sis lub sijhawm ua haujlwm ntawm lub sijhawm qis dua.

Daim ntawv muab cov kua dej ntawm cov tshuaj insulin no yog kev daws teeb meem rau kev tswj hwm ntawm cov dej, cov kua ntshiab ntshiab lossis tsis muaj ntshav. Ib ml ntawm cov tshuaj muaj 3.49 mg ntawm cov tshuaj nquag, uas yog sib npaug 100 IU ntawm tib neeg cov tshuaj insulin, nrog rau cov neeg tsis suav, suav nrog dej rau txhaj tshuaj thiab sodium hydroxide.

Tus nqi ntawm insulin Apidra sib txawv raws li tus nqi sib pauv tam sim no. Qhov nruab nrab hauv teb chaws Russia, tus mob ntshav qab zib tuaj yeem yuav ib cov tshuaj rau 2000-3000 txhiab rubles.

Kho kev nyhuv ntawm cov tshuaj

Cov kev ua yeeb yam tseem ceeb tshaj plaws ntawm Apidra yog qhov kev tsim nyog ntawm kev ua haujlwm ntawm cov ntshav qabzib hauv cov ntshav, insulin tuaj yeem txo qis cov piam thaj, thiaj li txhawb nws txoj kev nqus los ntawm cov ntaub so ntswg:

Cov tshuaj insulin txwv kev tsim cov piam thaj hauv tus neeg mob lub siab, adipocyte lipolysis, proteolysis, thiab nce protein ntau.

Hauv kev tshawb fawb qhia txog cov neeg muaj kev noj qab haus huv thiab cov neeg mob ntshav qab zib mellitus, nws tau pom tias subcutaneous tswj hwm ntawm glulisin muab cov nyhuv sai dua, tab sis nrog lub sijhawm luv dua, thaum piv nrog soluble tib neeg cov kua dej.

Nrog kev siv tshuaj subcutaneous ntawm cov tshuaj, cov nyhuv hypoglycemic yuav tshwm sim li ntawm 10-20 feeb, nrog cov tshuaj txhaj rau cov nyhuv no yog sib npaug hauv lub zog rau qhov kev txiav txim ntawm tib neeg insulin. Chav Apidra yog tus cwj pwm los ntawm kev ua haujlwm hypoglycemic, uas sib npaug rau chav ntsuas ntawm tib neeg cov kua dej.

Apidra insulin muab rau 2 feeb ua ntej noj mov, uas tso cai rau kev tswj tus mob glycemic tom qab noj mov, zoo ib yam li tib neeg cov insulin, uas tau siv 30 feeb ua ntej noj mov. Nws yuav tsum tau sau tseg tias xws li kev tswj hwm yog qhov zoo tshaj plaws.

Yog hais tias glulisin noj 15 feeb tom qab noj mov, nws tuaj yeem tswj tau qhov kev tswj hwm ntawm cov ntshav qab zib, uas sib npaug rau tib neeg cov tshuaj insulin ua rau 2 feeb ua ntej noj mov.

Cov tshuaj insulin yuav nyob hauv cov ntshav li 98 feeb.

Cov lus qhia rau kev siv tshuaj

Kev qhia txog kev siv tshuaj insulin Apidra SoloStar yog insulin-tiv thaiv ntshav qab zib mellitus ntawm hom thawj thiab hom thib ob, cov tshuaj no tuaj yeem kho rau cov laus thiab menyuam yaus hnub nyoog 6 xyoo.Cov tshuaj tiv thaiv yuav yog hypoglycemia thiab ib tug neeg tsis kam txais rau ib feem twg ntawm cov tshuaj.

Thaum cev xeeb tub thiab pub niam mis, Apidra yog siv nrog kev ceev faj heev.

Kev siv tshuaj insulin tam sim ntawd ua ntej noj mov lossis 15 feeb ua ntej. Nws tseem raug tso cai siv cov tshuaj insulin tom qab noj mov. Feem ntau, Apidra SoloStar pom zoo kom siv cov tshuaj insulin rau ib nrab-sijhawm ntev, nrog rau kev ua haujlwm ntev ntev ntawm insulin. Rau qee cov neeg mob, nws yuav raug suav nrog cov ntsiav tshuaj hypoglycemic.

Kev noj tshuaj ib leeg rau ib leeg yuav tsum tau xaiv rau txhua tus mob ntshav qab zib, noj rau hauv uas nrog lub raum tsis ua haujlwm, qhov kev xav tau rau cov tshuaj hormone no tseem tsawg heev.

Cov tshuaj muaj peev xwm tso cai rau noj tshuaj subcutaneously, infusion rau hauv thaj chaw ntawm cov rog subcutaneous. Cov chaw yooj yim tshaj plaws rau kev siv tshuaj insulin:

Thaum muaj qhov xav tau txuas ntxiv Txoj kev lis ntshav, txoj kev qhia yog nqa tawm ntawm lub plab. Cov kws kho mob xav pom zoo hloov chaw txhaj tshuaj, nco ntsoov ntsuas kev ntsuas kev nyab xeeb. Qhov no yuav tiv thaiv kev nkag ntawm insulin mus rau hauv cov hlab ntshav. Kev tswj hwm hauv qab ntu ntawm phab ntsa hauv thaj chaw ntawm lub plab yog qhov kev lees paub txog kev nqus ntawm cov tshuaj ntau tshaj li nws qhov kev qhia mus rau lwm qhov ntawm lub cev.

Tom qab txhaj tshuaj, nws yog txwv tsis pub zaws qhov chaw txhaj tshuaj, tus kws kho mob yuav tsum qhia txog qhov no thaum lub sijhawm piav qhia txog cov txheej txheem kom raug rau kev tswj hwm cov tshuaj.

Nws yog ib qho tseem ceeb kom paub tias cov tshuaj no yuav tsum tsis txhob xyaw nrog lwm cov tshuaj insulins, tsuas yog kev zam rau txoj cai no nkaus xwb yog cov tshuaj insulin Isofan. Yog tias koj sib xyaw Apidra nrog Isofan, koj yuav tsum hu nws ua ntej thiab prick tam sim ntawd.

Daim cartridges yuav tsum siv nrog OptiPen Pro1 koob txhaj tshuaj lossis nrog cov khoom siv zoo sib xws, nco ntsoov ua raws li cov kws tsim cov lus pom zoo:

1. cartridge sau,
2. koom ib rab koob
3. kev qhia ntawm cov tshuaj.

Txhua lub sijhawm ua ntej siv cov cuab yeej, nws yog qhov tseem ceeb los ua qhov kev soj ntsuam ntawm nws; kev daws teeb meem txhaj tshuaj yuav tsum muaj qhov tsis pom tseeb, tsis muaj xim, uas tsis muaj kev pom pom tseeb.

Ua ntej kev teeb tsa, lub cartridge yuav tsum ceev cia nyob rau hauv chav tsev qhov tsawg kawg yog 1-2 teev, tam sim ntawd ua ntej kev qhia ntawm insulin, huab cua yog tshem tawm ntawm daim cartridge. Kev siv daim laub rov qab yuav tsum tsis txhob rov ntim tshuaj dua; Thaum siv lub tshuab nqus tsev twj tso kua mis los tsim cov tshuaj insulin tas mus li, sib xyaw nws yog qhov txwv!

Xav paub ntau ntxiv, thov nyeem cov lus qhia rau kev siv. Cov neeg mob hauv qab no yog kev kho tshwj xeeb:

• nrog lub raum khiav tsis zoo (yuav tsum tau los saib xyuas qhov koob tshuaj ntawm insulin),
• nrog lub siab ua haujlwm tsis zoo (qhov xav tau rau ib yam tshuaj hormones tuaj yeem txo qis).

Tsis muaj cov ntaub ntawv hais txog kev tshawb fawb pharmacokinetic ntawm cov tshuaj hauv cov neeg laus, txawm li cas los xij, nws yuav tsum tau yug los rau hauv lub siab tias cov pab pawg ntawm cov neeg mob no yuav txo qis qhov xav tau ntawm insulin vim muaj kev puas tsuaj lub raum.

Apidra insulin vials tuaj yeem siv nrog lub twj tso kua mis ua haujlwm ntawm lub cev, cov tshuaj insulin nrog cov ntsuas qhov tsim nyog. Tom qab txhua qhov kev txhaj tshuaj, rab koob raug tshem tawm ntawm rab koob txhaj tshuaj thiab muab pov tseg. Txoj hau kev no yuav pab tiv thaiv kev kis mob, khoo tshuaj, cua nkag mus, thiab txhaws ntawm rab koob. Koj sim tsis tau nrog koj kev noj qab haus huv thiab rov siv rab koob.

Txhawm rau tiv thaiv kev kis mob, tus cwj mem puv siv tsuas yog siv los ntawm ib qho mob ntshav qab zib, nws tsis tuaj yeem hloov mus rau lwm tus neeg.

Cov kab mob ntawm kev noj haus ntau tshaj thiab muaj kev cuam tshuam tsis zoo

Feem ntau, tus neeg mob ntshav qab zib muaj peev xwm tsim muaj qhov tsis zoo yam li ua rau lub cev tsis muaj ntshav qab zib.

Hauv qee kis, cov tshuaj ua rau cov tawv nqaij ua paug thiab o ntawm qhov chaw txhaj tshuaj.

Qee zaum nws yog lus nug txog yog tias tus neeg mob tsis tau ua raws li kev pom zoo ntawm kev hloov chaw ntawm kev siv tshuaj insulin.

Lwm cov kev tsis haum tshuaj suav nrog:

1. zawm caj pas, urticaria, tshuaj tiv thaiv kab mob dermatitis (feem ntau),
2. hauv siab nruj (tsis tshua muaj).

Nrog cov kev tshwm sim ntawm cov kev tawm tsam tsis haum, muaj kev phom sij rau tus neeg mob lub neej. Vim li no, nws tseem ceeb uas yuav tau ua tib zoo saib xyuas koj kev noj qab haus huv thiab mloog nws cov kev ntxhov siab me ntsis.

Thaum kev siv ntau tshaj ntawd tshwm sim, tus neeg mob nthuav dav hypoglycemia cov ua mob hnyav Hauv qhov no, kev kho mob yog qhia:

• mob ntshav qab zib tsawg - siv cov zaub mov uas muaj suab thaj (nyob rau hauv cov ntshav qab zib lawv yuav tsum nrog lawv nyob ib txwm)
• Kev mob ntshav qab zib ntau nrog rau qhov tsis nco qab - kev tso tseg tsis ua los ntawm kev tswj hwm 1 ml ntawm glucagon subcutaneously lossis intramuscularly, qabzib tuaj yeem muab tshuaj rau hauv ntshav (yog tias tus neeg mob tsis teb rau glucagon).

Sai li tus neeg mob rov qab nco ntsoov, nws yuav tsum tau noj me me ntawm carbohydrates.

Raws li qhov tshwm sim ntawm hypoglycemia lossis hyperglycemia, muaj kev pheej hmoo ntawm tus neeg mob lub cev tsis muaj peev xwm ua kom pom tseeb, hloov qhov ceev ntawm cov kev puas hlwb psychomotor. Qhov no ua rau muaj kev hem thawj thaum tsav tsheb lossis lwm yam txheej txheem.

Kev saib xyuas tshwj xeeb yuav tsum tau muab rau cov neeg mob ntshav qab zib uas muaj qhov txo qis lossis tsis tuaj yeem muaj peev xwm paub txog cov tsos mob ntawm lub siab ntog ntshav qab zib. Nws tseem yog qhov tseem ceeb rau kev mob ncua ntev ntawm skyrocketing qab zib.

Cov neeg mob zoo li no yuav tsum txiav txim siab txog qhov ua tau ntawm kev tswj hwm cov tsheb thiab cov txheej txheem ntawm tus kheej.

Nrog rau cov tib neeg siv cov tshuaj insulin Apidra SoloStar nrog rau qee yam tshuaj, ib qho nce lossis tsawg dua hauv kev txhawb nqa rau kev txhim kho hypoglycemia tuaj yeem pom, nws yog kev coj los suav nrog cov txhais tau tias:

1. qhov ncauj hypoglycemic,
2. ACE inhibitors
3. fibrates
4. Disopyramides,
5. MAO inhibitors
6. Fluoxetine,
7. Pentoxifylline
8. salicylates,
9. Propoxifene
10. sulfonamide antimicrobials.

Qhov ua rau lub ntsej muag ntshav siab tuaj yeem txo qis ntau zaus yog tias cov tshuaj insulin glulisin muab ua ke nrog cov tshuaj: diuretics, phenothiazine derivatives, thyroid hormones, protease inhibitors, antipsychotropic, glucocorticosteroids, Isoniazid, Phenothiazine, Somatropin, sympathomimetics.

Cov tshuaj Pentamidine yuav luag ib txwm muaj hypoglycemia thiab hyperglycemia. Ethanol, kua ntsev lithium, beta-blockers, cov tshuaj Clonidine tuaj yeem muaj peev xwm thiab muaj zog me ntsis cov nyhuv hypoglycemic.

Yog tias nws yuav tsum hloov ntshav qab zib rau lwm hom tshuaj insulin lossis lwm hom tshuaj tshiab, kev saib xyuas nruj los ntawm tus kws kho mob mus yog qhov tseem ceeb. Thaum kev siv tshuaj tsis txaus ntawm cov tshuaj insulin siv los yog tus neeg mob txiav txim siab txiav txim siab txog kev kho, qhov no yuav ua rau kev txhim kho:

Ob qho xwm txheej no ua rau muaj kev hem thawj rau lub neej ntawm tus neeg mob.

Yog tias muaj kev hloov pauv ntawm cov yam ntxwv lub cev, qhov ntau thiab cov zaub mov noj, kev hloov kho ntawm Apidra insulin kuj yuav tsum tau ua. Cov kev tawm dag zog lub cev uas tshwm sim tam sim ntawd tom qab noj mov tuaj yeem ua rau muaj qhov txo qis ntawm cov ntshav qab zib tsawg.

Ib hom tshuaj insulin uas muaj muag nyob hauv cov khw muag tshuaj yog insulin apidra. Cov tshuaj no yog cov tshuaj zoo, uas, raws li kws kho mob tau sau, tuaj yeem siv hom ntshav qab zib hom I hauv rooj plaub thaum lawv tus kheej tsim cov tshuaj insulin tsis txaus thiab nws yuav tsum tau txhaj. Cov tshuaj yog raug faib tawm los ntawm cov tshuaj noj thiab yuav tsum tau ua tib zoo suav tshuaj ntawm cov tshuaj. Nws yog tsiag ntawv los ntawm kev ua haujlwm siab thaum siv kom raug.

Daim ntawv tso tawm

Muaj nyob rau hauv daim ntawv ntawm cov kev daws rau kev txhaj tshuaj. Kev daws yog pob tshab, tsis muaj xim thiab tsis hnov ​​tsw. Npaj kom txhij rau cov thawj coj ncaj qha (tsis tas yuav tsum tov los yog zoo li).

Qhov no yog ib qho tshuaj tivthaiv uas nws lub ntsiab lus ua haujlwm tseem ceeb yog insulin glulisin. Tau los ntawm kev rov ua rog ntawm DNA. Tus kab mob E. coli tau siv.Tsis tas li ntawd nyob rau hauv cov muaj pes tsawg leeg muaj cov khoom pab tsim nyog rau kev npaj ntawm qhov raug ncua.

Nws ua tiav ntau yam. Nws tuaj yeem raug muag raws li kev txhaj tshuaj ntawm 3 ml txhua. Hauv 1 ml ntawm 100 IU. Ib qho kev xaiv rau kev xa ntawm kev txhaj tshuaj hauv ib lub thauv yog tau. Nws yog qhov yooj yim tshaj plaws los yuav insulin apidra hauv kev teeb tsa tiav nrog OptiSet syringe mem. Nws yooj yim txheej txheem ntawm kev siv tshuaj. Tsim rau 3 ml cartridge.

Tus nqi ntawm cov tshuaj thaum khaws 5 cartridges ntawm 3 ml yog 1700 - 1800 rubles.

Cov ntsiab lus, contraindications

Cov tshuaj no yog siv rau cov ntshav qab zib hom 1 yog qhov hloov pauv cov tshuaj insulin rau ntuj tsim, uas tsis tsim tawm hauv tus kab mob no (lossis raug tsim tawm hauv cov khoom tsis txaus). Nws kuj tseem tuaj yeem kho tus mob rau tus kabmob thib ob hauv rooj plaub thaum kev tiv thaiv (tiv thaiv kab mob) rau qhov ncauj tshuaj glycemic tau tsim.

Muaj cov tshuaj insulin apidra thiab contraindications. Zoo li ib qho kev kho mob zoo li no, nws tsis tuaj yeem nqa nrog kev nyiam los yog ncaj qha rau qhov hypoglycemia. Kev tsis nkag siab rau cov tshuaj tseem ceeb ntawm cov tshuaj lossis nws cov khoom sib txuas ua ke tseem ua rau qhov tseeb tias nws yuav tsum tau lawb tawm.

Thov

Cov cai ntawm kev tswj hwm tshuaj muaj raws li hauv qab no:

1. Qhia ua ntej (tsis pub dhau 15 feeb) lossis tom qab noj mov tas,
2. Nws yuav tsum tau siv nrog kev sib xyaw ua ke ntev ntev lossis tib yam kev kho mob hauv qhov ncauj,
3. Qhov ntau npaum li cas yog teem nruj nruj rau ib tus zuj zus thaum teem sijhawm nrog tus kws kho mob tuaj koom,
4. Muab tshuaj subcutaneously,
5. Xav tau qhov chaw txhaj tshuaj: ncej puab, plab, deltoid leeg, pob tw,
6. Nws yog ib qho tsim nyog yuav tau hloov chaw txhaj tshuaj,
7. Thaum qhia los ntawm lub plab phab ntsa, cov tshuaj nqus thiab pib ua kom sai dua,
8. Koj tsis tuaj yeem zaws qhov chaw txhaj tshuaj tom qab cov tshuaj,
9. Saib xyuas yuav tsum saib xyuas kom tsis txhob ua rau cov hlab ntshav,
10. Txhaum ntawm kev ua txhaum ntawm kev ua haujlwm tsis zoo ntawm lub raum, nws yog qhov yuav tsum tau txo qis thiab rov suav cov tshuaj ntawm cov tshuaj,
11. Thaum lub siab tsis ua hauj lwm zoo, cov tshuaj yuav tsum tau siv nrog ceev faj - xws li kev tshawb fawb tsis tau ua, tab sis muaj laj thawj ntseeg tias qhov tshuaj hauv qhov no yuav tsum raug txo, txij li qhov xav tau insulin tsawg dua vim tias txo qis glucogenesis.

Ua ntej pib siv, koj yuav tsum mus ntsib koj tus kws kho mob los suav seb qhov zoo tshaj plaws ntawm cov tshuaj

Cov tshuaj Epidera muaj analogues ntawm insulins. Cov no yog cov nyiaj uas muaj cov khoom siv tseem ceeb, tab sis kev coj ua lub npe sib txawv. Lawv muaj cov nyhuv sib xws ntawm lub cev. Cov no yog cov cuab yeej xws li:

Thaum hloov los ntawm ib cov tshuaj rau lwm tus, txawm tias ib qho tshuaj analogue, koj yuav tsum tau sab laj nrog kws kho mob.

Cov Chaw Tsim Tshuaj: Sanofi-Aventis Private Co. Ltd. (Sanofi-Aventis Tsoomfwv Co. Ltd.) Fabkis

PBX Code: A10AB06

Daim foos tso tawm: Cov ntawv siv tshuaj ua kua. Kev daws rau kev txhaj tshuaj.

Kev taw qhia rau kev siv:

Cov yam ntxwv dav dav. Muaj pes tsawg leeg:

Cov khoom siv nquag: insulin glulisin - 100 PIECES (3.49 mg),
kev zam: metacresol (m-cresol) 3.15 mg, trometamol (tromethamine) 6.0 mg, sodium chloride 5.0 mg, polysorbate 20 0.01 mg, sodium hydroxide rau pH 7.3, hydrochloric acid rau pH 7 3, dej rau kev txhaj tshuaj txog 1.0 ml.

Kev piav qhia Pob tshab tsis muaj xim ua kua.

Cov yam ntxwv Pharmacological:

Cov Tshuaj Hauv Tshuaj Cov tshuaj insulin glulisin yog qhov sib xyaw ua ke ntawm tib neeg cov tshuaj insulin, uas yog sib npaug hauv lub zog rau insulin tib neeg.
Qhov kev txiav txim tseem ceeb tshaj plaws ntawm insulin thiab insulin analogues, suav nrog insulin glulisin, yog kev cai ntawm cov metabolism hauv cov piam thaj. Cov tshuaj insulin txo cov concentration ntawm cov piam thaj hauv cov ntshav, txhawb kev nqus ntawm cov piam thaj los ntawm cov ntaub so ntswg, tshwj xeeb tshaj yog cov leeg pob txha thiab cov nqaij mos adipose, nrog rau inhibiting kev tsim cov piam thaj hauv lub siab. Cov tshuaj insulin muab cov lipolysis hauv adipocytes, inhibits proteolysis thiab nce cov synthesis protein.Cov kev tshawb fawb hauv cov neeg tuaj yeem noj qab haus huv thiab cov neeg mob ntshav qab zib mellitus pom tias nrog subcutaneous tswj hwm ntawm cov tshuaj insulin, glulisin pib ua haujlwm sai dua thiab muaj lub sijhawm luv luv ntawm kev ua dua li cov neeg ua kom tsis txhob muaj insulin. Nrog txoj kev tswj hwm subcutaneous, cov nyhuv ntawm insulin glulisin, uas txo cov concentration ntawm cov piam thaj hauv cov ntshav, pib tom qab 10-20 feeb. Thaum muab cov tshuaj pleev ib ce, qhov tshwm sim ntawm kev txo qis ntshav qabzib hauv cov ntshav ntawm insulin glulisin thiab solulin tib neeg cov kua dej ua kom sib luag hauv lub zog. Ib chav ntawm insulin glulisin muaj tib yam hypoglycemic yam li ib chav ntawm solulin tib neeg cov kua dej.
Hauv ib theem kuv qhov kev sim hauv cov neeg mob uas muaj hom 1 mob ntshav qab zib mellitus, hypoglycemic profiles ntawm insulin glulisin thiab soluble tib neeg insulin tau raug saib xyuas subcutaneously ntawm koob tshuaj ntawm 0.15 U / kg ntawm lub sijhawm sib txawv ntawm tus qauv noj haus 15 feeb. Cov txiaj ntsig ntawm txoj kev tshawb pom pom tias insulin glulisin, siv sijhawm 2 feeb ua ntej noj mov, tau muab tib yam glycemic tswj tom qab noj mov ib yam li soluble tib neeg cov tshuaj insulin, siv 30 feeb ua ntej noj mov. Thaum muab 2 feeb ua ntej noj mov, insulin glulisin muab glycemic tswj tau zoo tom qab noj mov dua li ntawm tib neeg cov tshuaj insulin tau siv 2 feeb ua ntej noj mov. Glulisin insulin, muab 15 feeb tom qab pib noj mov, muab tib yam glycemic tswj tom qab noj mov ib yam li soluble tib neeg insulin, muab 2 feeb ua ntej noj mov.
Ib theem kuv kawm ua nrog insulin glulisin, insulin lispro thiab solulin tib neeg cov kua dej hauv ib pawg neeg mob ntshav qab zib mellitus thiab rog rog tau qhia tias hauv cov neeg mob no insulin glulisin khaws nws txoj kev coj cwj pwm sai. Hauv qhov kev tshawb nrhiav no, lub sijhawm mus txog 20% ​​ntawm tag nrho AUC (thaj chaw hauv qab qhov ntsuas-sijhawm nkhaus) yog 114 feeb rau insulin glulisin, 121 feeb rau insulin lispro thiab 150 feeb rau solulin tib neeg, thiab AUC (0-2 teev), ua rau muaj kev cuam tshuam. kuj tseem ntxov hypoglycemic kev ua si, feem, yog 427 mg / kg rau insulin glulisin, 354 mg / kg rau insulin lispro, thiab 197 mg / kg rau solulin tib neeg cov kua dej.
Cov kev tshawb fawb soj ntsuam ntawm hom 1.
Hauv 26-lub lis piam kev soj ntsuam ntawm theem III, uas piv rau insulin glulisin nrog insulin lispro, tswj subcutaneously sai ua ntej noj mov (0-15 feeb), cov neeg mob uas muaj ntshav qab zib hom 1 siv insulin glargine li basal insulin, insulin glulisin yog piv nrog insulin lispro nyob rau hauv kev sib piv rau glycemic tswj, uas tau soj ntsuam los ntawm kev hloov pauv hauv kev xav ntawm glycosylated hemoglobin (Lb1c) thaum lub sij hawm ntawm txoj kev tshawb no xaus piv nrog thawj zaug. Tau saib xyuas cov ntshav qabzib nyob rau ntawm kev ntsuas tus kheej. Nrog rau kev tswj hwm ntawm insulin glulisin, hauv kev sib piv rau kev kho mob nrog insulin, lyspro tsis xav tau nce ntxiv ntawm cov koob tshuaj insulin basal.
Lub sijhawm 12 lub lis piam mus rau kev soj ntsuam hauv cov neeg mob uas muaj ntshav qab zib hom 1 uas tau txais insulin glargine ua kev kho mob tau qhia tias cov tshuaj insulin glulisin tswj tau tam sim ntawd tom qab noj mov tau muab piv rau qhov ntawm insulin glulisin tam sim ntawd ua ntej noj mov (rau 0-15 feeb) lossis soluble tib neeg cov insulin (30-45 feeb ua ntej noj mov).
Hauv cov pej xeem ntawm cov neeg mob uas ua tiav txoj kev tshawb no, nyob rau hauv pab pawg ntawm cov neeg mob uas tau txais insulin glulisin ua ntej noj mov, muaj qhov txo qis ntau dua HL1C piv nrog pab pawg ntawm cov neeg mob uas tau txais insulin tib neeg.

Mob ntshav qab zib Hom 2
26-lub lis piam theem kev soj ntsuam zaum tom qab 26-lub limtiam rov qab soj ntsuam kev nyab xeeb tau ua los piv rau insulin glulisin (0-15 feeb ua ntej noj mov) nrog soluble tib neeg insulin (30-45 feeb ua ntej noj mov), uas tau muab tshuaj subcutaneously rau cov neeg mob ntshav qab zib hom 2 mob ntshav qab zib, ntxiv rau siv tshuaj insulin-isofan ua cov tshuaj insulin. Qhov nruab nrab ntawm tus neeg mob lub cev qhov nruab nrab ntsuas yog 34.55 kg / m2. Cov tshuaj insulin glulisin qhia nws tus kheej piv rau soluble tib neeg insulin nrog kev hloov pauv hauv HL1C ntau tom qab 6 lub hlis kev kho mob piv nrog tus nqi pib (-0.46% rau insulin glulisin thiab -0.30% rau solulin tib neeg cov kua dej, p = 0.0029) thiab tom qab 12 lub hlis ntawm kev kho mob piv nrog thawj zaug tus nqi (-0.23% rau insulin glulisin thiab -0.13% rau solulin tib neeg cov kua dej, qhov sib txawv tsis tseem ceeb). Hauv qhov kev tshawb fawb no, feem ntau cov neeg mob (79%) tau sib xyaw luv luv ntawm insulin nrog insulin-isophan tam sim ntawd ua ntej txhaj tshuaj. 58 cov neeg mob thaum lub sijhawm ua randomization siv cov tshuaj hypoglycemic hauv qhov ncauj thiab tau txais cov lus qhia los txuas ntxiv noj lawv hauv ib qho (tsis hloov pauv) koob tshuaj.

Haiv neeg thiab tub los ntxhais
Hauv kev tswj xyuas cov kev kho mob hauv cov neeg laus, qhov sib txawv ntawm kev nyab xeeb thiab kev ua tau zoo ntawm insulin glulisin tsis pom nyob rau hauv kev txheeb xyuas ntawm pab pawg sib txawv los ntawm haiv neeg thiab poj niam txiv neej.

Cov Tshuaj Pharmacokinetics Hauv cov tshuaj insulin, kev hloov pauv ntawm cov amino acid asparagine ntawm tib neeg insulin ntawm txoj hauj lwm B3 nrog lysine thiab lysine ntawm txoj haujlwm B29 nrog glutamic acid txhawb nqa kom sai dua.

Kev Tsis Xiam thiab Bioavailability
Pharmacokinetic concentration-sijhawm nkhaus hauv cov neeg ua haujlwm zoo thiab cov neeg mob uas muaj hom 1 thiab hom 2 mob ntshav qab zib mellitus qhia tau tias kev nqus ntawm insulin glulisin piv rau soluble tib neeg insulin yog kwv yees li 2 zaug sai dua, thiab qhov siab tshaj plaws ntshav pliav tiav (Stax) yog kwv yees li 2 ntau zaus ntxiv.
Hauv txoj kev tshawb nrhiav rau cov neeg mob uas muaj hom 1 mob ntshav qab zib mellitus, tom qab ua haujlwm subcutaneous ntawm insulin glulisin ntawm koob tshuaj ntawm 0.15 U / kg, Tmax (lub sijhawm pib ntawm qhov siab tshaj plaws ntshav ntshav) yog 55 feeb, thiab Stm yog 82 ± 1.3 mcU / ml piv nrog Tmax ntawm 82 feeb thiab Cmax ntawm 46 ± 1.3 μU / ml rau solulin tib neeg cov kua dej. Lub sijhawm nyob hauv lub nruab nrab nyob rau hauv cov kab ke rau cov ntshav insulin glulisin tau luv dua (98 feeb) dua rau cov tib neeg cov kua dej insulin (161 feeb).
Hauv kev tshawb nrhiav nyob rau hauv cov neeg mob uas muaj hom 2 mob ntshav qab zib mellitus tom qab subcutaneous tswj hwm ntawm insulin glulisin ntawm koob tshuaj ntawm 0.2 PIECES / kg, Stax yog 91 mcU / ml nrog interquartile latitude ntawm 78 rau 104 mcU / ml.
Nrog kev tswj hwm subcutaneous ntawm insulin glulisin hauv thaj av ntawm sab xub ntiag phab ntsa, ncej puab, lossis xub pwg (hauv thaj tsam ntawm deltoid cov leeg), kev nqus tau sai dua thaum qhia rau thaj av ntawm sab xub ntiag phab ntsa piv nrog cov thawj coj ntawm cov tshuaj hauv tus ncej puab. Tus nqi ntawm kev nqus ntawm thaj av deltoid yog nruab nrab.
Qhov kev txiav txim siab tsis txaus ntseeg ntawm insulin glulisin tom qab kev tswj hwm subcutaneous yog kwv yees li 70% (73% los ntawm anterior plab phab ntsa, 71 los ntawm deltoid leeg thiab 68% los ntawm thaj chaw muaj pojniam) thiab muaj qhov tsis tshua pom kev hauv cov neeg mob sib txawv.

Kev xa Khoom
Kev faib khoom thiab kev tawm ntawm cov insulin glulisin thiab soluble tib neeg cov kua dej tom qab kev tswj hwm zoo ib yam, nrog cov faib tawm ntawm 13 litres thiab 21 litres thiab ib nrab ntawm lub neej ntawm 13 thiab 17 feeb, feem.

Chaw Sau Ntawv
Tom qab ua haujlwm subulinaneous ntawm insulin, glulisin yog tawm sai dua soluble tib neeg insulin, muaj qhov pom meej ib nrab-lub neej ntawm 42 feeb, piv nrog pom meej ib nrab-lub neej ntawm soluble tib neeg insulin ntawm 86 feeb.Hauv kev soj ntsuam ib ntu ntawm insulin glulisin kev tshawb fawb hauv cov tib neeg noj qab haus huv thiab cov muaj ntshav qab zib hom 1 thiab ntshav qab zib hom 2, pom meej txog ib nrab lub neej nyob ntawm 37 txog 75 feeb.

Pab Pawg Neeg Tshwj Xeeb

Cov neeg mob raum tsis ua haujlwm
Hauv qhov kev tshawb fawb soj ntsuam nyob rau hauv cov tib neeg tsis muaj ntau yam kev ua haujlwm ntawm lub raum (kev tsim lub peev xwm tshem tawm (CC)> 80 ml / min, 30¬50 ml / feeb, 1/10, hom:> 1/100, 1/1000, 1 / 10000,

Qhov sib txawv ntawm cov tshuaj insulin

Nyob rau theem no ntawm kev txhim kho cov tshuaj ib txwm muaj, luv luv ua yeeb yam insulin thiab siv tshuaj ntev ntev tau tsim. Txhua hom tshuaj noj nws muaj nws cov subspecies. Xws li kev faib tawm ua rau peb cais cov tshuaj raws lub sijhawm thiab cov tshuaj tiv thaiv. Cov tshuaj insulin luv luv yog hu ua zaub mov, thiab nrog lub sijhawm ntev - hauv paus.

Ntawm cov tshuaj nrog kev ua ntev ntev, ob hom tau paub qhov txawv: insulin ntawm nruab nrab ncua ntev thiab tshuaj noj nrog lub cev ntev. Lawv raug siv los qoj ib ce zoo ntawm cov kua dej tso zis ib hnub. Piv txwv ntawm kev tsim qauv ntev yog detemir thiab glargine, thiab kev tsim tawm nrog lub sij hawm ua nruab nrab ntev tuaj yeem yog Lente thiab NPH.

Kev npaj yeeb yaj yeeb luv luv yog tsim kom muaj peev xwm nres qhov chaw noj mov. Cov tshuaj insulin ultrasonic tuaj yeem pib nws cov haujlwm hauv 10-15 feeb. Cov tshuaj insulin luv luv pib siv lawv cov nyhuv tom qab ib nrab ib teev.

Tab sis qhov kev sib pauv ntawm cov hom tshuaj tsis yog sib txawv ntawm lawv. Piv txwv li, ICD yuav tsum txhaj rau hauv lub plab ncaj qha, uas yuav ua rau kev ua kom sai ntawm kev nqus ntawm cov khoom noj.

Cov tshuaj noj ntawm lub sijhawm ntev dhau los yuav tsum tau txhaj rau hauv tus ncej puab. Cov tshuaj ntawm ultrashort thiab cov yeeb yaj kiab luv luv yuav tsum tau muab nrog ua ke nrog cov txheej txheem khoom noj khoom haus.

Qhov no yuav tsum tau ua ib nrab teev ua ntej noj mov. Cov tshuaj yog qhov ntev thiab nruab nrab lub sijhawm koj yuav tsum nkag los ntawm lub sijhawm.

Qhov no tau ua tiav raws li lub sijhawm nruj thaum sawv ntxov thiab yav tsaus ntuj. Koj tuaj yeem ua ke lawv txoj kev siv nrog ib qho yeeb tshuaj sai sai yog tias qhov no tau ua thaum sawv ntxov.

Kev npaj nrawm tas yuav tsum noj mov tom ntej los ntawm tus neeg mob. Koj tsis tuaj yeem ua txhaum cov kev cai no, txwv tsis pub pib ntawm hypoglycemia tuaj yeem ua raws.

Tab sis cov tshuaj ntev ntev tsis txuam nrog cov zaub mov, yog li yog tias tsis muaj qhov tsis qab los noj mov, koj tuaj yeem hla kev noj mov.

Qhov tshwm sim ntawm cov tshuaj insulin

Cov tshuaj nrog lub sijhawm ntev ntawm qhov kev txiav txim, yog tias qhia hauv qab ntawm daim tawv nqaij, pib tshwm tom qab ob peb teev siab kawg. Lub ncov ntawm lawv cov haujlwm tuaj yeem pib tom qab 6 lossis 8 teev txij li lub sijhawm tswjhwm. Feem ntau, tag nrho lub sijhawm raug kwv yees li 10-12 teev. Muaj ntau chav kawm ntawm lawv cov neeg sawv cev.

Piv txwv li, Monotard yog insulin-zinc, Protafan thiab Monodar yog hom kab mob monocomponent raws li kev loj hlob ntawm npua. Qhov no yog ib qho piv txwv ntawm cov tshuaj insulin isophane. Muaj ob hom tshuaj uas tau tsim los ntawm tib neeg cov tshuaj hormones. Thawj hom yog hluavtaws ib nrab. Nws suav nrog Humodar thiab Biogulin. Hom ob, tso tawm los ntawm caj ces, suav nrog Gensulin, Insuran, Biosulin thiab lwm yam.

Ntawm cov ntshav qab zib mellitus ntawm hom thib ob, kev sib txuas ua ke ntawm kev ua ke tuaj yeem siv. Lawv hu ua cov khoom sib xyaw lossis cov khoom lag luam tshuaj biphasic. Lawv tau tsim los ua kev sib tov ntawm cov tshuaj sai thiab ntev ua yeeb yam. Ntxiv mus, lawv muaj lub cim hauv daim ntawv ntawm ib feem. Thawj tus naj npawb yog qhov feem pua ​​ntawm cov tshuaj yeeb-luv luv, thiab qhov thib ob yog qhov feem pua ​​ntawm cov tshuaj ncua ntev.

Feem ntau, cov lus qhia ntawm kev siv tshuaj sib xyaw 2 zaug hauv ib hnub. Qhov no tuaj yeem ua tau thaum sawv ntxov thiab yav tsaus ntuj. Thaum noj su, koj tuaj yeem nkag mus rau urea sulfonyl nrog qib thib peb. Nws yog qhov zoo dua los qhia qhov sib xyaw ib nrab ib teev ua ntej noj mov. Qhov no yog vim qhov tseeb tias lawv muaj ib qho yeeb yam nrawm nrawm.

Ntawm cov neeg sawv cev ntawm daim ntawv ntawm cov tshuaj no, ob-theem raug cais.Nws yog semi-hluavtaws, raws li tib neeg lub cev. Piv txwv ntawm cov tshuaj no yog Biogulin, Humodar, Humalog thiab lwm yam. Muaj ob-qib tshuaj los ntawm qeb ntawm txhob kaw cov tshuaj hloov raws li tib neeg cov tshuaj hormones. Cov no suav nrog Gansulin, Insurman, Humalin, thiab lwm yam.

Thaum siv cov tshuaj insulin, lipodystrophy ntawm thaj chaw txhaj tshuaj yuav pib. Lipodystrophy yog txheej txheem uas cov roj ntau hauv cov tawv nqaij txo qis.

Qee qhov tsis tshua muaj mob, insulin tuaj yeem ua rau ua xua. Hauv cov xwm txheej zoo li no, koj yuav tsum tau tsum tsis txhob siv cov tshuaj thiab hloov nws nrog cov tshuaj tiv thaiv zoo.

Ua raws li hom mob ntshav qab zib mellitus, koj tuaj yeem xaiv cov tshuaj raws li qee yam: yooj yim ntawm kev siv sijhawm, ntau zaus, sijhawm ua.

Cov tshuaj niaj hnub yuav pab ua kom yog qhov yog.

Kuv puas tuaj yeem ua yam tsis muaj kev txhaj tshuaj insulin rau cov ntshav qab zib?

Cov neeg mob ntshav qab zib, uas muaj cov ntshav qabzib hauv lub cev tsis txaus, tswj tau kom cov piam thaj ib txwm tsis tas siv tshuaj insulin. Txawm li cas los xij, lawv yuav tsum npaj kho cov tshuaj insulin, vim tias qee kis lawv yuav tsum tau txhaj tshuaj thaum mob khaub thuas thiab lwm yam kab mob sib kis. Thaum lub sij hawm muaj kev ntxhov siab ntau ntxiv, tus txiav yuav tsum tau tswj hwm los ntawm kev tswj hwm ntawm insulin. Txwv tsis pub, tom qab muaj kev mob luv, mob ntshav qab zib tuaj yeem ua rau tag nrho koj lub neej.

Ntau yam ntawm kev ua yeeb yam ceev ceev

Ua raws li cov txheej txheem ntau lawm, kev npaj kho tshuab kho kom zoo thiab cov tib neeg cov khoom sib cais raug rho tawm. Cov nyhuv pharmacological ntawm tom kawg yog ntau lub zog, vim tias cov qauv hauv tshuaj lom neeg ntawm cov tshuaj no zoo ib yam rau tib neeg cov insulin. Txhua yam tshuaj sib txawv hauv lub sijhawm ua.

Cov tshuaj insulins luv luv yog siv los ua ntsiag to stimulated hormone ua ke nrog kev ua kom zaub mov noj. Qeb theem kev txhawb nqa tshuaj nrog qhov ntev.

Cov tshuaj no tau faib raws li lub sijhawm txiav txim. Muaj cov kev txhaj tshuaj ntawm cov hauv qab no:

• ultrashort hno,
• luv luv txhaj
• nruab nrab sijhawm
• Lub sijhawm ntev txhaj tshuaj.

Cov hom kev txhaj tshuaj no cim cov sijhawm uas cov tshuaj ua haujlwm, txo cov ntshav qab zib kom qis.

Txoj kev kho yog nqa tawm tam sim los ntawm ntau hom tshuaj. Qhov no tso cai rau koj kom zoo tswj lub suab thaj thiab zam kom nws tsis txhob ua rau nws.

Muaj ib lub rooj hauv qhov uas cov ntsiab lus ntawm kev ua ntawm txhua hom kev txhaj tshuaj tau piav qhia txhua yam. Txhua tus neeg mob ntshav qab zib yuav tsum pom cov ntaub ntawv no hauv lawv tus kws kho mob lub chaw haujlwm.

Cov tshuaj insulin luv luv pib ua li ib nrab ib teev tom qab kev tswj hwm. Qhov siab tshaj plaws ntawm cov tshuaj hormones hauv cov ntshav tshwm sim kwv yees li 3.5 teev tom qab txhaj, thiab tom qab ntawd nws qib poob qis. Qhov nruab nrab, luv insulin kav ntev txog 5-6 teev.

Ultrashort insulin pib ua haujlwm ob peb feeb tom qab kev tswj hwm. Qhov siab tshaj plaws nce mus txog 60 feeb tom qab kev tswj hwm, thiab tom qab ntawd ib qho kev poob qis pib. Feem ntau, cov tshuaj insulin ultrashort kav ntev tsis tshaj 4 teev.

Cov insulins uas tau teev tseg yog suav tias yog kev tshuaj ntsuam genetic ntawm tib neeg, tsuas yog Monodar, uas yog hu ua npua. Muaj nyob hauv daim ntawv ntawm kev daws teeb meem nyob rau hauv vials. Txhua tus npaj rau kev kho mob ntawm hom 1 thiab ntshav qab zib hom 2. Feem ntau sau tseg ua ntej siv tshuaj yeeb ntev.

Kev ua haujlwm tag nrho ntawm kev ua haujlwm ntawm tus txiav ua kab mob rau tus neeg noj qab haus huv tso cai rau lub cev ua kom tswj cov metabolism hauv cov zaub mov muaj kuab zoo rau lub siab tus thaum nruab hnub. Thiab tseem yuav tiv nrog lub nra ntawm cov carbohydrates thaum noj mov los yog kis thiab ua mob ntawm kab mob.

Yog li no, txhawm rau kom tswj tau cov piam thaj hauv cov ntshav, ib yam tshuaj hormones nrog cov yam ntxwv zoo ib yam, tab sis nrog kev ceev nrawm ntawm kev ua, yog qhov tsim nyog. Hmoov tsis zoo, tam sim no, science tsis tau pom txoj kev daws teeb meem no, tab sis cov kev kho mob nyuaj nrog ob hom tshuaj xws li ntev ntev thiab luv insulin tau dhau los ua kev cawm dim rau cov neeg mob ntshav qab zib.

Ntxiv rau cov saum toj no, muaj cov tshuaj insulin sib xyaw ua ke, uas yog, ncua kev kawm, uas tib lub sij hawm muaj ob qho tshuaj hormones. Ntawm ib sab, qhov no txo ​​cov naj npawb ntawm cov kev xav tau los ntawm cov ntshav qab zib, uas yog qhov loj ntxiv. Txawm li cas los xij, hauv qhov no, nws tsis yooj yim kom muaj qhov sib npaug ntawm cov khoom noj metabolism.

Thaum siv cov tshuaj no, nws yog ib qho tsim nyog yuav tsum tswj hwm tus nqi ntawm cov carbohydrates noj, kev siv lub cev, kev ua neej nyob rau hauv dav dav. Qhov no yog vim qhov tsis muaj peev xwm ntawm kev xaiv qhov ntau npaum li cas ntawm yam xav tau tam sim no ntawm cov tshuaj insulin cais.

Kuj muaj ntau, qhov ntev ntawm kev ua yeeb yam kuj hu ua keeb kwm yav dhau los. Nws qhov nqus tau muab lub cev nrog cov tshuaj insulin rau lub sijhawm ntev.

Kev nqus los ntawm subcutaneous adipose cov nqaij mos maj mam, cov tshuaj nquag tso cai rau koj kom muaj cov suab thaj nyob hauv ib qho kev txwv thoob plaws hnub. Raws li txoj cai, tsis pub ntau tshaj peb koob ib hnub yog qhov txaus rau qhov no.

Raws li lub sijhawm ua ntawm kev coj ua, lawv muab faib ua peb hom:

1. Lub sijhawm nruab nrab. Qhov tshuaj hormones pib ua tom qab 1.5 qhov siab tshaj plaws ntawm 2 teev tom qab ua haujlwm ntawm cov tshuaj, yog li ntawd, hno nws ua ntej. Hauv qhov no, qhov siab tshaj ntawm cov tshuaj tshwm sim tsis pub dhau 3-12 teev. Lub sijhawm ntawm kev ua haujlwm dav dav los ntawm tus neeg sawv cev hauv nruab nrab yog 8 teev txog 12 teev, yog li ntawd, tus kws kho ntshav qab zib yuav tau siv nws 3 zaug rau 24 teev.
2. Lub sijhawm ntev kis. Kev siv ntawm hom tshuaj no ntev li ntawm lub cev yuav qhia tau cov keeb kwm yav dhau los ntawm cov hormone kom txaus kom tau cov kua nplaum thoob plaws ib hnub. Lub sijhawm ntawm nws cov yeeb yam (16-18 teev) yog txaus thaum noj tshuaj rau thaum sawv ntxov ntawm lub plab khoob thiab yav tsaus ntuj ua ntej yuav mus pw. Qhov siab tshaj plaws ntawm cov tshuaj yog los ntawm 16 rau 20 teev los ntawm lub sijhawm nws nkag mus rau hauv lub cev.
3. Superlong nkaus. Tshwj xeeb tshaj yog yooj yim rau cov laus thiab cov neeg xiam oob khab muab lub sijhawm ua haujlwm ntawm cov khoom (24-36 teev) thiab, yog li ntawd, kev txo qis rau zaus ntawm nws txoj kev tswj hwm (1 p. Hauv 24 teev). Qhov kev txiav txim pib hauv 6-8 teev, nrog lub ncov ntawm kis hauv lub sijhawm 16-20 teev tom qab nkag mus rau hauv cov nqaij mos adipose.

Kev kho tshuaj Insulin cuam tshuam nrog qog qhov ntuj zais ntawm qhov hormone los ntawm kev siv tshuaj. Hmoov tsis zoo, nws tsis yooj yim sua kom ua tiav cov ntsuas zoo siv tsuas yog ib qho ntawm hom kev ua haujlwm ntawm cov tshuaj hormones. Tias yog vim li cas luv luv ua yeeb yam insulins tsis muaj tsawg qhov tseem ceeb hauv tus nqi.

Lub npe ntawm hom tshuaj no hais rau nws tus kheej.

Nyob rau hauv kev sib piv rau cov tshuaj ua yeeb yaj kiab ntev, luv luv tau tsim los them rov qab txhawm rau hauv qabzib hauv lub cev tshwm sim los ntawm qee yam xws li:

• kev noj
• kev tawm dag zog ntau dhau
• muaj cov kis thiab inflammatory txheej txheem,
• kev ntxhov siab hnyav thiab khoom siv.

Kev siv cov khoom noj ntawm carbohydrates hauv cov zaub mov nce lawv cov kev xav hauv cov ntshav txawm tias thaum noj cov tshuaj insulin.

Los ntawm lub sijhawm sib xyaw ua ke, cov tshuaj hormones maj nrawm raug faib ua ob hom:

1. Luv. Kev npaj tshuaj insulin luv luv tom qab kev tswj hwm pib ua nyob rau hauv 30-60 feeb. Muaj lub peev txheej resorption siab, qhov siab ntawm qhov ua tau zoo tshaj plaws tau ua tiav ntawm 2-4 teev tom qab noj. Raws li kev kwv yees kwv yees, cov nyhuv ntawm cov tshuaj zoo li no tsis pub ntev tshaj 6 teev.
2. Cov tshuaj insulin ultrasonic. Qhov hloov kho ntawm cov roj ntsha ntawm tib neeg cov tshuaj hormones yog qhov tshwj xeeb hauv qhov nws muaj peev xwm ua tau sai dua li ib txwm muaj tshwm sim los ntawm insulin. Twb tau 10-15 feeb tom qab txhaj tshuaj, cov tshuaj nquag pib nws cov nyhuv ntawm lub cev nrog lub ncov pom tshwm sim li 1-3 teev tom qab txhaj tshuaj. Cov nyhuv kav rau 3-5 teev. Qhov ceev uas daws cov teeb meem ntawm kev kho mob ultrashort yog nqus tau mus rau hauv lub cev, tso cai rau koj coj nws ua ntej noj mov lossis tam sim ntawd.

Kev xaiv cov tshuaj hormone haum rau kev siv yog tus neeg nruj me ntsis, vim nws yog los ntawm kev kuaj, qhov ntsuas ntawm tus neeg mob ntshav qab zib, keeb kwm tiav, kev ua neej. Tsis yog qhov tseem ceeb tshaj plaws yog tus nqi ntawm cov tshuaj, muab qhov zaus ntawm nws txoj kev siv. Raws li txoj cai, nws yog kev faib ua feem ncaj ncaj nyob hauv kev faib ua feem ncaj ncaj rau cov khoom siv yeeb tshuaj, teb chaws tsim khoom lag luam, ntim khoom.

Ultrashort hom insulin yog Humalog (Lizpro), NovoRapid (Aspart) thiab Apidra (Glulizin). Lawv tau tsim los ntawm peb lub tuam txhab tshuaj sib txawv uas cov neeg sib tw nrog ib leeg. Cov tshuaj insulin luv luv yog tib neeg, thiab ultrashort yog cov qauv, piv txwv li, hloov kho, txhim kho, piv nrog insulin tib neeg tiag. Qhov kev txhim kho yog qhov tseeb uas lawv pib txo cov ntshav qab zib kom nrawm dua li cov luv luv ib txwm - 5-15 feeb tom qab txhaj.

Ultrashort insulin analogues tau tsim kom qeeb cov piam thaj hauv ntshav thaum muaj ntshav qab zib xav noj cov zaub mov sai. Hmoov tsis zoo, lub tswv yim no tsis ua haujlwm rau hauv kev xyaum. Carbohydrates, uas tam sim ntawd nqus, tseem nce ntshav qab zib sai dua txawm tias qhov tseeb tshaj tawm luv luv insulin tswj kom nws tsawg dua. Nrog kev pib ua cov insulin tshiab no ntawm kev ua lag luam, tsis muaj leej twg tau tso tseg qhov kev xav tau los ua raws li cov zaub mov tsis muaj roj ntau ntau thiab ua raws li cov txheej txheem ntawm cov khoom me. Yog lawm, koj yuav tsum tau ua raws li kev tswj hwm tsuas yog koj xav kom tswj tau ntshav qab zib kom zoo thiab zam rau nws cov teeb meem.

Yog tias koj ua raws li cov zaub mov uas tsis muaj carbohydrate tsawg rau cov ntshav qab zib hom 1 lossis hom 2, tom qab ntawd cov tshuaj insulin luv luv yog qhov zoo dua rau kev txhaj tshuaj ua ntej noj mov dua li ultra-short counterparts. Vim hais tias nyob rau hauv cov neeg mob ntshav qab zib uas haus me ntsis carbohydrates, lub cev thawj zaug zom cov protein, thiab tom qab ntawd hloov qee qhov ntawm nws mus rau hauv qabzib. Qhov no yog tus txheej txheem qeeb, thiab cov tshuaj insulin ultrashort pib ua haujlwm sai dhau. Luv luv hom insulin - txoj cai. Lawv feem ntau yuav tsum tau pricked 40-45 feeb ua ntej cov zaub mov muaj cov carbohydrate tsawg.

Cov tshuaj Insulin "Apidra" - rau cov menyuam yaus muaj ntshav qab zib

Tsoom Fwv Saib Xyuas Kev Noj Qab Haus Huv Israeli tau pom zoo siv cov tshuaj insulin Apidra (insulin Glulizin), uas yog ib qho piv txwv ntawm cov roj ntsha sai sai rau kev siv los ntawm cov menyuam yaus txij li 6 xyoo nrog mob ntshav qab zib.

Kev Pom Zoo rau Apidra insulin siv yog raws li 26-lub lim tiam qhib daim ntawv qhia ua los ntawm FDA (Asmeskas Khoom Noj thiab Tshuaj) uas koom nrog 572 tus menyuam. Cov txiaj ntsig ntawm kev kawm tau ua pov thawj kev nyab xeeb ntawm kev noj thiab qhov ua tau zoo ntawm cov tshuaj no hauv cov menyuam yaus thiab cov hluas.

Tsis ntev los no, Apidra insulin tau sau npe nyob hauv Asmeskas thiab tau tso cai rau cov menyuam muaj hnub nyoog 4 xyoos, nyob hauv EU lub teb chaws - rau cov menyuam yaus thiab cov tub ntxhais hluas pib txij 6 xyoo.

Apidra insulin, tsim los ntawm cov tuam txhab tshuaj thoob ntiaj teb Sanofi Aventis, yog ib qho piv txwv ntawm cov insulin ceev ceev, uas muaj qhov pib sai thiab lub sijhawm luv luv ntawm kev ua. Nws qhia rau cov neeg mob uas muaj mob ntshav qab zib hom 1 thiab ntshav qab zib hom 2, pib txij 6 xyoo. Cov tshuaj tshwm sim nyob rau hauv daim ntawv ntawm rab koob txhaj tshuaj lossis lub tshuaj txau.

Apidra muab sijhawm rau cov neeg mob xav txog kev txhaj tshuaj thiab sijhawm noj mov ntau. Yog tias tsim nyog, insulin Apidra tuaj yeem siv nrog cov insulin ntev ntev xws li Lantus.

Txog ntshav qab zib

Mob ntshav qab zib mellitus yog ib qho mob ntev, tshwm sim ntau heev los ntawm kev poob qis hauv kev zais ntawm cov tshuaj insulin lossis nws qhov kev ua haujlwm qis qis. Cov tshuaj insulin yog ib yam tshuaj xav los hloov cov piam thaj (piam thaj) rau hauv lub zog.

Txij li thaum tus txiav yuav luag lossis tsis tsim muaj cov tshuaj insulin, cov neeg mob ntshav qab zib hom 1 yuav tsum tau txhaj tshuaj insulin txhua hnub hauv lawv lub neej. Ntawm hom 2 mob ntshav qab zib mellitus, tus txiav ua ntej tsim cov tshuaj insulin, tab sis lub cev ua rau lub cev tsis zoo cuam tshuam rau kev cuam tshuam ntawm cov tshuaj hormone, uas ua rau cov txheeb ze insulin tsis txaus.

Raws li kev txheeb cais, 35,000 cov menyuam yaus uas muaj ntshav qab zib nyob hauv cov neeg Ixayees. International Kev Ntshav Qab Zib Federation (IDF) kwv yees tias muaj 440,000 cov menyuam yaus hnub nyoog qis dua 14 nrog cov mob ntshav qab zib hom 1 thoob ntiaj teb uas raug tshawb pom muaj 70,000 tus mob tshiab txhua xyoo.

Cov yam ntxwv ntawm kev xaiv ntawm cov yeeb yam luv luv ua yeeb yam. Cov tshuaj uas nrov tshaj plaws

Cov tshuaj uas tsis siv yuav tsum nyob hauv tub yees. Cov cuab yeej rau kev siv txhua hnub yog khaws cia hauv chav sov li 1 hli. Ua ntej cov lus qhia ntawm insulin, nws lub npe, rab koob patency tau txheeb xyuas, qhov pom tseeb ntawm kev daws thiab hnub tas sij hawm tau raug ntsuas.

Cov ntawv qog ua ib qho raug muab txhaj rau hauv qhov nqaij ntawm lub plab. Ntawm thaj chaw no, txoj kev daws teeb meem nquag thiab pib ua haujlwm sai. Qhov chaw txhaj tshuaj hauv thaj chaw no tau hloov pauv txhua hnub.

Thaum siv cov koob txhaj tshuaj, nws yog qhov yuav tsum tau xyuas qhov tseeb ntawm cov tshuaj uas tau qhia rau ntawm nws thiab lub vial. Raws li txoj cai, nws yog 100 U / ml. Thaum lub caij cov tshuaj yeeb tshuaj, ib daim tawv nqaij tsim, qhov kev txhaj tshuaj yog tsim ntawm kaum ntawm 45 degrees.

Muaj ntau hom koob txhaj tshuaj:

• Npaj ua ntej (npaj los siv) - Apidra SoloStar, Humalog QuickPen, Novorapid Flexpen. Tom qab kev daws teeb meem tiav lawm, tus kov yuav tsum tau muab pov tseg.
• Siv tau rov qab, nrog daim lev ntim tshuaj insulin uas hloov tau - OptiPen Pro, OptiKlik, HumaPen Ergo 2, HumaPen Luxura, Cwj mem Biomatic.

Ua ntej siv lawv, ib qho kev xeem twg yog ua nrog uas kev soj ntsuam ntawm rab koob raug ntsuas. Txhawm rau ua qhov no, nce ntxiv 3 yam tshuaj thiab nias tawm qhov ntsuas phom. Yog tias poob ntawm cov tshuaj tshwm ntawm nws cov taub, koj tuaj yeem hno cov tshuaj insulin. Yog tias qhov tshwm sim tsis zoo, qhov kev ntxias coj mus ua dua 2 zaug ntxiv, thiab tom qab ntawd lub koob tau hloov mus rau qhov tshiab. Nrog tus tsim tsim subcutaneous rog txheej, kev tswj hwm ntawm tus neeg sawv cev yog nqa ntawm lub kaum sab xis.

Cov tshuaj insulin yog cov cuab yeej uas pab txhawb rau cov hauv paus thiab cov qib kev loj hlob ntawm cov tshuaj hormones. Lawv txhim kho cartridges nrog ultrashort analogues. Kev ua ntu zus los ntawm kev sib xyaw me me ntawm kev daws nyob rau hauv cov nqaij mos subcutaneous ua raws li cov keeb kwm hormonal li qub thaum nruab hnub thiab hmo ntuj, thiab cov lus qhia ntxiv ntawm kev ua kom zoo tshaj plaws txo cov piam thaj uas tau txais los ntawm cov zaub mov.

Ua ntej koj yuav cov tshuaj hauv khw muag tshuaj, koj yuav tsum sab laj nrog koj tus kws kho mob txog cov yam ntxwv ntawm daim ntawv thov. Txawm hais tias qhov tseeb tias cov ntaub ntawv no muaj cov lus qhia rau cov tshuaj, nyob rau qee kis, kev hloov kho me me kuj tsim nyog.

Ntau npaum li cas yog ib qho tshuaj insulin yuav tsum tau nrhiav cov ncaj qha hauv lub tsev muag tshuaj. Hauv kev qhia txhua yam ntawm hom tshuaj insulin yog dab tsi thiab seb lawv ua dab tsi txawv, tus kws kho mob yuav muaj peev xwm qhia tau, sau ntawv noj tshuaj tshwj xeeb.

Insulins Ultrashort muaj cov npe nram qab no: Novorapid, Apidra. Qhov twg zoo dua, tsuas yog tus kws kho mob tuaj yeem teb tau, raws li cov yam ntxwv ntawm chav kawm ntawm tus kab mob hauv cov neeg mob tshwj xeeb.

Cov npe insulins luv luv muaj ntau lub npe, uas tau piav qhia txhua yam hauv cov rooj ntawm cov chaw ua haujlwm ntawm endocrinologist. Nws yog tsis yooj yim sua kom ywj siab siv cov tshuaj tsis muaj kev sab laj ib tus kws kho mob tshwj xeeb.

Kev siv tshuaj insulin luv luv yog siv raws li cov txheej txheem uas muaj cov lus qhia rau kev siv. Txawm li cas los xij, yog tias tsim nyog, kev muab tshuaj yog kho los ntawm kws kho mob.

Tshuaj
681, Cov Npe Pauv -
125, Yam muaj sia -
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Los ntawm cov khoom hauv tshooj dhau los ntawm tsab xov xwm, nws thiaj li paub meej dab tsi luv luv insulin, tab sis tsis tsuas yog lub sijhawm thiab nrawm kis raug tseem ceeb. Txhua cov tshuaj muaj lawv tus kheej cov yam ntxwv, ib qho tshuaj noj tsis haum ntawm tib neeg pancreatic hormone yog tsis muaj kev zam.

Daim ntawv teev cov yam ntxwv ntawm cov tshuaj uas koj yuav tsum tau them sai sai rau:

• qhov uas tau txais
• degree ntawm huv si
• mloog zoo
• pH ntawm cov tshuaj
• chaw tsim tshuaj paus thiab cov khoom ua ke.

Yog li, piv txwv li, ib qho piv txwv ntawm cov tsiaj keeb kwm yog tsim los ntawm kev kho tus kab mob npua thiab tom qab ntawd ntxuav nws. Rau cov tshuaj tiv thaiv ib nrab hluavtaws, tib cov tsiaj cov tsiaj coj los ua lub hauv paus thiab, siv txoj kev ntawm kev hloov pauv enzymatic, insulin tau txais ze ze ntawm ntuj. Cov thev naus laus zis no feem ntau yog siv rau cov tshuaj hormones luv.

Kev txhim kho ntawm kev tsim kho caj ces tau ua rau nws muaj peev xwm ua kom rov ua cov hlwb tiag tiag ntawm tib neeg cov kua dej los ntawm Escherichia coli nrog kev hloov pauv hloov caj ces. Cov tshuaj hormones Ultrashort, raws li txoj cai, yog hu ua cov tshuaj tiv thaiv cov noob ua tshuaj ntawm tib neeg cov kua dej.

Qhov nyuaj tshaj plaws los tsim cov kev daws teeb meem yog cov yeej huv (mono-tivthaiv). Qhov tsis muaj zog tsawg, qhov ua kom zoo dua thiab muaj qhov tsawg dua qhov kev cuam tshuam rau nws siv. Txoj kev pheej hmoo ntawm kev tsis haum tshuaj siv lub cev analogue txo.

Kev npaj ntawm cov txheej txheem sib txawv, cov nqi raug, cov tuam txhab, cov hom, tuaj yeem sawv cev los ntawm ntau qhov sib txawv. Yog li, tib lub koob tshuaj insulin tuaj yeem nyob ntawm ntau qhov sib txawv hauv cov koob txhaj tshuaj.

Kev siv cov tshuaj nrog cov nruab nrab acidity yog qhov zoo dua, qhov no zam qhov tsis hnov ​​tsw ntawm qhov chaw txhaj tshuaj. Txawm li cas los xij, tus nqi ntawm cov peev nyiaj no muaj ntau dua li cov kua qaub.

Txij li thaum sia mus thoob ntiajteb, kev tshawb fawb yog qhov tseem ceeb ua ntej ntawm kev tshawb fawb hauv tsev, nws feem ntau lees txais cov tshuaj los ntawm cov teb chaws tsim tau zoo dua thiab muaj txiaj ntsig zoo. Cov khoom siv txawv teb chaws tuaj ntawm cov tuam txhab lag luam zoo yog raws li cov nqi ntau hauv cov nqi.

Muab hais tias txhua yam kab mob ib leeg ib leeg thiab kev phomsij rau tshuaj ntawm ib qho hom twg kuj yuav txawv. Siv cov txheej txheem ntawm kev siv tshuaj insulin, nyob rau hauv uas cov tshuaj tau muab peb zaug ib hnub ua ntej noj mov, cov neeg mob ntshav qab zib feem ntau siv cov npe insulin luv luv, uas tau qhia hauv lub rooj.

Cov lus tsis tas 2. Cov npe ntawm cov tshuaj tua kab mob feem ntau yog kws kho mob tshwj xeeb.

Feem ntau, cov tshuaj analogues ntawm tib neeg cov tshuaj insulin yog tsim nyob rau hauv kev saib xyuas ntawm 40/100 IU, hauv lub raj mis los yog daim cartridges npaj rau siv hauv cov koob txhaj tshuaj.

Yuav luag txhua qhov ntawm cov txhais tau niaj hnub no ntawm cov pab pawg insulin muaj ntau qhov tsawg dua qhov kev tiv thaiv tsis zoo ntawm lawv cov neeg ua ntej. Lawv feem ntau raug tso cai siv thaum cev xeeb tub thiab lactation.

Dua li ntawm qhov tseeb tias ultra-luv-ua yeeb yam insulin tau tsim los pab thaum muaj xwm txheej ceev hauv qabzib, tshem tus neeg ntawm hyperglycemic coma, tam sim no nws yog siv rau kev kho tshuaj insulin. Thaum lub sijhawm tam sim no, kev soj ntsuam kuaj mob tau ua tiav nrog peb yam tshuaj hormones ntawm kev ua zoo sib xws.

Cov lus tsis. 3. Sau cov tshuaj tiv thaiv kab mob los ntawm kev ua kom lub cev tiv thaiv kab mob.

Ib tug neeg, ua ntej txhaj cov tshuaj hormones luv-luv, yuav tsum tau xam ua ntej thiab tswj cov nyiaj uas tau los ntawm cov zaub mov carbohydrates nrog cov zaub mov.Qhov no yog vim qhov tseeb tias qhov tau suav cov tshuaj ntawm cov tshuaj yog muab 30-40 feeb ua ntej noj mov.

Feem ntau, cov neeg mob ntshav qab zib nrog lub sijhawm ua haujlwm ntab dej hauv qhov nws nyuaj rau kev twv ua ntej thaum noj mov ua ntej muaj teeb meem tswj cov metabolism hauv cov pluas noj. Nws tsis yooj yim rau cov niam txiv ntawm cov menyuam muaj ntshav qab zib. Yog tias tus me nyuam tsis noj zaub mov tsis txaus lossis tus me nyuam tsis kam noj txhua lub sijhawm, kev noj tshuaj insulin yav dhau los yuav ntau dhau, uas tuaj yeem ua rau muaj ntshav qab zib ntshav siab heev.

Cov tshuaj kho mob siab ntawm ib pawg ultrashort zoo heev vim tias lawv tuaj yeem noj yuav luag thooj txhij nrog zaub mov lossis tom qab. Qhov no ua rau nws muaj peev xwm xaiv qhov ntau ntxiv ntawm cov koob tshuaj uas tsim nyog thaum lub sijhawm.

Nws yuav tsum raug sau tseg tias kev tshawb fawb thiab kev tsim caj ces tsis sawv ntsug. Cov kws tshawb fawb niaj hnub hloov kho thiab hloov kho cov tshuaj uas twb muaj lawm, tsim dua tshiab thiab hloov kho tshiab raws lawv.

Ntau cov qauv ntawm cov kua dej insulin tau txais cov muaj koob npe, tso cai rau koj los ua tus yam ntxwv lub neej thaum ntsib kev tsis tshua zoo los ntawm kev txhaj tshuaj. Ua tsaug rau qhov no, lub neej zoo ntawm kev tiv thaiv insulin-cov neeg tau dhau los ua ntau dua.

Cov khoom siv yees duab yuav tso cai rau koj kom pom tseeb kom pom cov txheej txheem ntawm kev coj cov tshuaj no.

Kev txhaj tshuaj insulin yog nqa tawm los ntawm kev siv tshuaj insulin los yog cwj mem-xaum hluav taws xob. Cov tom kawg tau yooj yim dua los siv thiab ntau dua cov koob tshuaj, yog li lawv nyiam. Koj tuaj yeem muab txhaj tshuaj nrog ib tus xaum xaum xaum tsis tau hle koj cov khaub ncaws, uas yooj yim, tshwj xeeb tshaj yog tias tus neeg ntawd ua haujlwm lossis hauv tsev kawm ntawv.

Cov tshuaj insulin raug txhaj rau hauv cov nqaij mos subcutaneous ntawm qhov chaw sib txawv, feem ntau nws yog sab ua ntej ntawm tus ncej, plab thiab xub pwg. Kev ua yeeb yaj kiab ntev yog qhov zoo dua rau prick hauv tus ncej lossis sab nraud gluteal quav, luv luv ua yeeb yam hauv plab lossis xub pwg.

Ib qho yuav tsum tau ua ua ntej yog ua raws li cov cai aseptic, nws yog qhov tsim nyog los ntxuav koj txhais tes ua ntej kev txhaj tshuaj thiab siv cov koob txhaj tshuaj siv pov tseg nkaus xwb. Nws yuav tsum nco ntsoov tias dej cawv rhuav tshem cov tshuaj insulin, yog li ntawd, tom qab qhov chaw txhaj tshuaj tau kho nrog ib qho tshuaj tua kab mob, nws yog ib qho tsim nyog yuav tsum tau tos kom txog thaum nws qhuav tag, thiab tom qab ntawd ua mus nrog cov thawj coj ntawm cov tshuaj. Nws tseem yog ib qho tseem ceeb rau kev rhuav tshem ntawm qhov chaw txhaj tshuaj dhau los tsawg kawg 2 centimeters.

Cov tshuaj insulin luv luv tau los ntawm ob txoj kev:

1. Txhob kaw, cov tshuaj hormones yog synthesized los ntawm cov kab mob.
2. Semi-hluavtaws, siv kev hloov pauv ntawm tus npua enzymes.

Ob hom tshuaj no hu ua tib neeg, vim los ntawm lawv cov amino acid muaj pes tsawg leeg lawv ua tiav cov qog tshuaj uas tsim nyob rau hauv peb lub txiav.

Daim ntawv thov nta

Cov tshuaj muaj tshuaj yog tsim hauv qhov kev daws teeb meem uas tau txhaj rau hauv cov nqaij mos. Ua ntej kev txhaj tshuaj ntawm insndial insulin, cov kua nplaum ntawm lub ntsej muag raug ntsuas siv cov glucometer. Yog tias cov suab thaj nyob ze rau cov qauv uas tau tsim rau tus neeg mob, ces cov ntawv luv luv yog siv 20-30 feeb ua ntej noj mov, thiab ultra-luv luv tam sim ntawd ua ntej noj mov. Yog tias qhov ntsuas tau dhau tus nqi uas siv tau, lub sijhawm ntawm kev txhaj tshuaj thiab zaub mov yog nce ntxiv.

Cov tshuaj ntawm cov tshuaj yog ntsuas hauv cov koog (UNITS). Nws tsis hloov pauv thiab tau muab cais ua ntej noj tshais, noj su thiab noj hmo. Thaum txiav txim siab ntau npaum li cas ntawm cov tshuaj, theem ntawm cov piam thaj ua ntej noj mov thiab qhov ntau ntawm cov zaub mov carbohydrates uas tus neeg mob npaj yuav noj yog xav txog.

Txog kev yooj yim, siv lub tswv yim ntawm chav ua mov ci (XE). 1 XU muaj 12-15 grams ntawm carbohydrates. Cov yam ntxwv ntawm feem ntau cov khoom tau nthuav tawm hauv cov ntawv tshwj xeeb.

Piv txwv tias ib tus neeg muaj ntshav qab zib muaj 8.8 mmol / L ntawm kev yoo ntshav qab zib thaum sawv ntxov nyob rau ntawm lub plab khoob (muaj ib lub hom phiaj ntawm 6.5 mmol / L), thiab nws npaj yuav noj 4 XE rau pluas tshais.Qhov sib txawv ntawm kev xaiv kom zoo thiab qhov ntsuas tau tseeb yog 2.3 mmol / L (8.8 - 6.5). Yuav kom txo qis qab zib kom ib txwm tsis suav rau hauv cov zaub mov noj, 1 UNIT ntawm insulin yog qhov yuav tsum tau, thiab nrog 4 XE, lwm qhov 6 UNITS ntawm cov tshuaj (1.5 UNITS * 4 XE) yuav tsum muaj. Yog li, ua ntej noj mov, tus neeg mob yuav tsum nkag mus rau 7 chav dej ntawm qhov muaj cov tshuaj pleev (1 chav 6 ib pawg).

Cov tshuaj xav kom ceev faj cia. Qhov kev xaiv zoo tshaj plaws yog khaws cov tshuaj rau hauv lub tub yees. Yog li nws tsis lwj kom txog thaum kawg ntawm lub sijhawm qhia los ntawm tus neeg tsim khoom hauv pob.

Hauv chav tsev kub, txhua hom tshuaj insulin raug muab khaws cia rau tsis pub dhau ib hlis, tom qab ntawv nws cov khoom ua rau muaj kev cuam tshuam loj. Nws yog qhov zoo tshaj plaws kom luv luv insulin hauv lub tub yees, tab sis tsis nyob ze ntawm lub tub yees.

Feem ntau cov neeg mob tsis pom tias cov tshuaj tau hloov zuj zus mus. Qhov no ua rau muaj qhov tseeb tias cov tshuaj txhaj tsis ua haujlwm, cov piam thaj nce siab. Yog tias koj tsis hloov cov tshuaj kom ncav sijhawm, muaj qhov pheej hmoo loj ntawm kev tsim muaj mob hnyav, mus txog rau lub dag zog tsis nco qab.

Nyob rau hauv tsis muaj qhov xwm txheej yuav tsum cov tshuaj khov los yog raug rau ultraviolet hluav taws xob. Txwv tsis pub, nws yuav piam zuj zus thiab nws siv tsis tau.

Qee tus neeg uas muaj lub ntsej muag tshwj xeeb txhua hnub nrog kaj ntug tsim tawm ntau cov tshuaj hormones: cortisol, glucagon, adrenaline. Lawv yog antagonists ntawm hom tshuaj insulin. Hormonal secretion vim yog ib tus yam ntxwv tuaj yeem hla dhau thiab sai. Hauv cov ntshav qab zib, hyperglycemia yog txiav txim siab thaum sawv ntxov. Xws li cov tsos mob tshwm sim. Nws yuav luag tsis yooj yim sua kom tshem tawm. Tib txoj kev tawm yog ib txoj kev txhaj tshuaj tiv thaiv ultra-luv insulin mus txog rau chav nyob, ua rau thaum sawv ntxov.

Feem ntau, muaj cov kev hais daws ultrafast rau cov pluas noj. Vim tias nws qhov kev ua haujlwm siab, kev txhaj tshuaj tuaj yeem muab tau ob qho tib si thaum noj mov thiab tam sim ntawd. Lub sijhawm luv luv ntawm lub zog ntawm insulin yuam tus neeg mob kom ua rau ntau qhov kev txhaj tshuaj thaum nruab hnub, qog ua qhov ntuj tsim tawm ntawm lub caj pas txiav tawm ntawm kev noj cov khoom noj khoom haus carbohydrate hauv lub cev. Los ntawm tus naj npawb ntawm cov zaub mov noj, txog li 5-6 zaug.

Txhawm rau kom tshem tawm qhov teeb meem loj ntawm metabolic cuam tshuam nyob rau hauv coma lossis precomatose xeev, thaum kis mob thiab raug mob tshuaj ultrashort siv tsis muaj kev sib txuas nrog lub zog ntev. Siv lub ntsej muag glucometer, uas yog, ib qho khoom siv los txiav txim siab txog qib qab zib, lawv soj ntsuam glycemia thiab rov qab kho kom qhov mob tsis zoo.

Cov npe ntawm ultrashort insulin tsis paub rau txhua tus. Lawv tau txiav txim siab hauv kab lus.

Hauv kev tawm dag zog ntawm lub cev, lawv nquag siv cov cuab yeej zoo li qhov muaj txiaj ntsig anabolic tseem ceeb, uas yog cov hauv qab no: cov hlwb nqus cov amino acids ntau cov nquag, protein biosynthesis nce ntau.

Ultra-luv-ua yeeb yam insulin kuj tseem siv nyob rau hauv lub cev tsim. Cov khoom pib pib ua 5-10 feeb tom qab kev tswj hwm. Ntawd yog, kev txhaj tshuaj yuav tsum tau nqa tawm ua ntej noj mov, lossis tam sim ntawd tom qab. Qhov siab tshaj plaws ntawm cov kua dej yog soj ntsuam 120 feeb tom qab nws tswj hwm. Cov tshuaj zoo tshaj plaws tau suav hais tias yog "Actrapid NM" thiab "Humulin tsis tu ncua."

Ultrashort insulin hauv kev tawm dag zog tsis cuam tshuam rau kev ua haujlwm ntawm lub siab thiab lub raum, nrog rau potency.

Kev taw qhia rau kev tswj hwm ntawm luv luv insulin

Cov tshuaj insulin yog kho rau cov ntshav qabzib feem ntau hauv ntau hom ntshav qab zib. Kev taw qhia rau kev siv cov tshuaj hormone yog cov kab mob hauv qab no:

• Ntshav qab zib Hom 1 muaj feem nrog autoimmune kev puas tsuaj rau cov hlwb endocrine thiab kev txhim kho ntawm cov tsis muaj tshuaj tiv thaiv hormone,
• Hom 2, uas yog tus yam ntxwv tsis muaj qhov txheeb ze vim tsis muaj cov tshuaj insulin vim muaj qhov tsis xws luag nyob rau hauv nws cov lus sib txuas lossis txo qis rau qhov rhiab ntawm cov ntaub so ntswg mus rau nws qhov kev ua,
• Mob ntshav qab zib hauv kev xeeb tub hauv cov poj niam cev xeeb tub
• pancreatic daim ntawv ntawm tus kab mob, uas yog tshwm sim los ntawm tus mob huam los yog mob leeg txham,
• cov kab mob uas tsis muaj kev tiv thaiv kab mob - syndromes ntawm Wolfram, Rogers, MODY 5, neonatal ntshav qab zib thiab lwm tus.

Txheem, luv insulin yog ua ke nrog cov tshuaj nruab nrab thiab ntev: luv luv yog muab ua ntej noj mov, thiab ntev - thaum sawv ntxov thiab ua ntej mus pw.Tus naj npawb ntawm kev txhaj tshuaj ntawm cov tshuaj hormone tsis yog txwv thiab tsuas yog nyob ntawm qhov xav tau ntawm tus neeg mob. Txo kom txo cov tawv nqaij puas tsuaj, cov qauv yog 3 hno ua ntej txhua pluas noj thiab qhov ntau kawg ntawm 3 hno txhawm rau kom kho hyperglycemia. Yog tias cov piam thaj nce sai sai ua ntej noj mov, txoj kev tswj kom zoo yog koom nrog kev npaj ua kom noj tshuaj.

Thaum koj xav tau cov tshuaj insulin luv:

1. 1 yam mob ntshav qab zib.
2. 2 hom mob thaum cov tshuaj txo suab thaj yuav siv tsis tau txaus.
3. Mob ntshav qab zib muaj ntshav qabzib ntau ntau. Rau theem yoojyim, 1-2 txhaj tshuaj ntawm cov insulin ntev feem ntau txaus.
4. Kev txiav phais txiav, uas ua rau cov tshuaj synthesis tsis hnov ​​lus.
5. Kev kho mob ntawm mob hnyav cov ntshav qab zib: ketoacidotic thiab hyperosmolar coma.
6. Lub sijhawm ntawm cov khoom siv insulin ntau ntxiv: cov mob kub thiab txias, mob plawv, hloov khoom nruab nrog, mob hnyav.

Kev tiv thaiv ntawm lipodystrophy

Tus mob ntshav qab zib yuav tsum tau saib xyuas kev tiv thaiv ntawm lipodystrophy. Lub hauv paus ntawm nws yog malfunctions ntawm kev tiv thaiv kab mob, ua rau muaj kev puas tsuaj ntawm fiber ntau hauv qab daim tawv nqaij. Cov tsos ntawm atrophied thaj chaw vim qhov kev txhaj tshuaj ntau zaus tsis cuam tshuam nrog qhov ntau ntawm cov tshuaj lossis cov nyiaj them tsis zoo rau ntshav qab zib.

Insulin edema, ntawm qhov tsis tooj, yog qhov tsis tshua muaj tshwm sim ntawm cov kab mob endocrine. Txhawm rau kom tsis txhob hnov ​​qab thaj chaw txhaj tshuaj, koj tuaj yeem siv cov txheej txheem uas qhov chaw ntawm lub plab (caj npab, ceg) tau muab faib ua cov ntu raws cov hnub ntawm lub limtiam. Tom qab ob peb hnub, daim tawv nqaij npog ntawm thaj chaw uas tau pom zoo yog rov zoo los nyab xeeb.

Vim li cas ultrashort insulin ua haujlwm zoo lossis tsis zoo rau ntshav qab zib?

Insulin Apidra (Epidera, Glulisin) - tshuaj xyuas

Kuv xav hais ob peb lo lus, thiaj li mus hais lus hauv kev nrhiav kub, hais txog kev hloov ntawm lub cim xeeb mus rau apidra. Kuv tig mus rau nws hnub no thiab tam sim no. Kuv tau zaum ntawm lub humulin NPH humalogue rau ntau tshaj 10 xyoo. Kuv kawm txhua qhov zoo thiab qhov tsis zoo ntawm humalogue, ntawm uas muaj ntau ntau. Ob peb xyoos dhau los kuv tau pauv mus rau apidra tau 2-3 lub hlis, raws li muaj kev cuam tshuam hauv tsev kho mob nrog tus neeg ntawm humalogue.

Raws li kuv nkag siab nws, kuv tsis yog ib qho xwb. Thiab koj paub, ntau yam ntawm cov teeb meem uas kuv twb tau rov sib haum xeeb ploj mus sai. Qhov teeb meem tseem ceeb yog qhov cuam tshuam thaum sawv ntxov. Qab zib ntawm lub plab khoob ntawm apidra dheev los ua ruaj khov. Nrog lub humalogue, txawm li cas los xij, tsis muaj kev sim nrog kev ntsuas ntawm qhov ntawm qhov ntawm qhov ntawm lub cev thiab NPH, thiab tsis kuaj qab zib thoob plaws hmo ntuj, tau ua tiav.

Nyob rau hauv luv luv, Kuv dhau ib pawg ntawm kev sim, mus dhau ntau tus kws kho mob, thiab peb tus kws kho mob endocrinologist thaum kawg sau ntawv rau kuv tus apidra hloov chaw ntawm lub humalogue. Hnub no yog thawj hnub uas kuv tau mus ua hauj lwm nrog nws. Cov tshwm sim yeej phem. Nws tau ua txhua yam niaj hnub no kiag li yog tias nws tau txhaj koob tshuaj pleev rau qhov khoob, thiab tsuas yog tsam nws tau nchuav qab zib ntau rau hauv nws lub hnab ris. Ua ntej noj tshais, thaum 8 teev a.m. muaj 6.0, uas kuv xav tias tsis muaj dab tsi.

Kuv tau daig nrog apidra, noj tshais, txhua yam yog li qub raws li XE, Kuv tuaj txog tom haujlwm thaum 10:00. Qab Zib 18.9! Ntxuav qhov no yog kuv kiag li “cov ntaub ntawv”! Nws zoo nkaus li tias kuv tsuas yog tsis txhaj. Txawm hais tias cov tshuaj insulin luv luv yuav ua rau kom muaj txiaj ntsig zoo. Tau kawg, kuv tam sim ntawd tau ntxiv rau 10 qhov ntxiv, vim tias kuv xav tias nws tsis tsim nyog mus nrog cov suab thaj. Thaum tav su, thaum 13:30, sk twb yog 11.1 lawm. Hnub no kuv kos qab zib txhua teev thiab ib nrab.

Kev tshawb xav: Yam tsawg kawg yuav tsum tau

Raws li koj paub, insulin yog yam tshuaj tsim los ntawm beta hlwb ntawm cov txiav. Nws ua rau cov piam thaj txo qis, ua rau cov ntaub so ntswg kom nqus cov piam thaj, uas ua rau nws cov ntsiab lus hauv cov ntshav txo qis. Koj kuj yuav tsum paub tias qhov tshuaj hormones no ua rau lub cev hloov pauv ntawm cov rog, txhawm rau rhuav tshem cov ntaub so ntswg adipose. Hauv lwm lub ntsiab lus, cov tshuaj insulin siab ua rau poob qhov tsis txaus.

Cov tshuaj insulin ua haujlwm li cas hauv lub cev?

Thaum ib tus neeg pib noj, txiav ua kab zais zais cia cov tshuaj hormones no loj li 2-5 feeb. Lawv pab kom ua kom cov ntshav qab zib sai sai tom qab noj mov kom nws tsis txhob nyob ntev ntev thiab qhov mob ntshav qab zib tsis muaj sij hawm tsim.

Tseem Ceeb! Tag nrho cov tshuaj insulin npaj muaj kev puas tsuaj heev, yooj yim yaig. Kawm cov cai khaws cia thiab ua raws li lawv kom zoo.

Tsis tas li ntawd nyob rau hauv lub cev txhua lub sij hawm ib qho insulin me me nthuav tawm hauv lub plab thiab txawm tias thaum ib tus neeg tuag tshaib rau ntau hnub ua ke. Qib Theem no hauv cov ntshav yog hu ua keeb kwm yav dhau los. Yog tias nws yog xoom, kev hloov pauv ntawm cov leeg thiab cov nruab nrog cev rau cov kua nplaum yuav pib. Ua ntej kev tsim cov tshuaj insulin, cov neeg mob ntshav qab zib hom 1 tau tuag los ntawm qhov no. Cov kws kho mob txheej thaum ub tau piav txog qhov lawv kawm thiab xaus ntawm lawv cov kab mob ua "tus neeg mob melted rau hauv qab zib thiab dej." Tam sim no qhov no tsis tshwm sim nrog tus mob ntshav qab zib. Qhov kev hem thawj loj yog cov kev mob nyhav.

Ntau tus neeg mob ntshav qab zib uas tau raug kho nrog insulin pom tias nws tsis yooj yim ua kom tsis txhob muaj ntshav qab zib qis thiab nws cov tsos mob txaus ntshai. Qhov tseeb, tuaj yeem khaws cov suab thaj kom ruaj khov Txawm hais tias muaj mob hnyav autoimmune. Thiab ntau heev tshaj dua yog li, nrog cov mob hnyav hom 2 mob ntshav qab zib. Tsis tas yuav tso cov qib ntshav koj cov ntshav qabzib los txhawm rau txhawm rau txhawm rau txhawm rau tiv thaiv ntshav qog ntshav qab zib.

Saib ib daim vis dis aus uas Dr. Bernstein tham txog qhov teeb meem no nrog leej txiv ntawm tus menyuam uas muaj ntshav qab zib hom 1. Kawm seb yuav ua li cas sib npaug ntawm cov khoom noj thiab cov tshuaj insulin.

Txhawm rau muab cov tshuaj insulin sai sai rau cov khoom noj, cov hlwb ua khoom noj thiab nthuav tawm cov tshuaj no hauv nruab nrab ntawm cov pluas noj. Hmoov tsis zoo, nrog rau txhua yam ntshav qab zib, txoj kev ua no raug cuam tshuam rau thawj qhov chaw. Tus mob ntshav qab zib muaj cov khw muag insulin tsawg los tsis muaj nyob rau hauv tus txiav. Raws li qhov tshwm sim, cov ntshav qab zib tom qab noj mov tseem nce rau ntau teev. Qhov no maj mam ua rau muaj teeb meem.

Qib nrawm nrawm ntsuas dej ntawm insulin yog hu ua theem pib. Txhawm rau kom nws haum, ua kom cov tshuaj tiv thaiv ntev tshaj thaum tsaus ntuj thiab / lossis thaum sawv ntxov. Cov no yog cov nyiaj hu ua Lantus, Tujeo, Levemir, Tresiba thiab Protafan.

Tresiba yog cov tshuaj zoo tshaj plaws uas lub chaw tswj hwm tau npaj ib daim yeeb yaj kiab hais txog nws.

Qhov loj ntawm cov tshuaj hormones, uas yuav tsum tau muab nrawm nrawm rau cov khoom me me ntawm cov zaub mov, hu ua bolus. Txhawm rau muab rau lub cev, txhaj ntawm luv luv lossis ultrashort insulin ua ntej noj mov. Kev siv tshuaj insulin ntev thiab nrawm yog hu ua qhov pib-bolus regimen ntawm insulin txoj kev kho. Nws suav hais tias yog teeb meem, tab sis muab cov txiaj ntsig zoo tshaj plaws.

Cov qauv sim tsis tso cai tswj kev mob ntshav qab zib. Yog li no, Dr. Bernstein thiab endocrin-patient.com tsis pom zoo rau lawv.

Yuav ua li cas xaiv txoj cai, zoo insulin?

Nws tsis tuaj yeem mob ntshav qab zib nrog cov tshuaj insulin sai sai. Koj yuav tsum tau siv sijhawm ob peb hnub kom nkag siab txhua yam, thiab tom qab ntawv txuas ntxiv mus rau kev hno. Cov haujlwm tseem ceeb uas koj yuav tsum daws:

1. Txheeb xyuas cov kauj ruam 2 hom phiaj kho mob ntshav qab zib hom 1 lossis hom phiaj xwm tswj ntshav qab zib hom 1
2. Hloov mus rau kev noj zaub mov kom tsis muaj carb. Tus neeg mob ntshav qab zib hnyav dua kuj yuav tsum tau noj cov tshuaj metformin raws li lub sijhawm nrog tshuaj maj mam nce ntxiv.
3. Ua raws li qhov muaj zog ntawm qab zib rau 3-7 hnub, ntsuas nws nrog glucometer tsawg kawg 4 zaug hauv ib hnub - thaum sawv ntxov ntawm lub plab khoob ua ntej noj tshais, ua ntej noj su, ua ntej noj hmo, thiab txawm tias thaum hmo ntuj ua ntej mus pw.
4. Lub sijhawm no, kawm siv cov tshuaj insulin txhaj tshuaj tsis mob thiab kawm txoj cai tswjhwm insulin.
5. Cov niam txiv ntawm cov menyuam uas muaj ntshav qab zib hom 1 yuav tsum nyeem ntawv txhawm rau txhawm rau tshuaj insulin. Coob tus neeg mob ntshav qab zib kuj tseem xav tau qhov no thiab.
6. Nkag siab yuav ua li cas thiaj paub qhov tseeb muab cov insulin ntev ntev, nrog rau xaiv cov koob tshuaj sai sai ua ntej noj mov.
7. Kawm cov ntawv xov xwm "Cov Kev Ntshav Qab Zib Qis (Ntshav Qab Zib Qis)", khaws hauv qab ntawm cov ntsiav tshuaj nyob rau hauv lub tsev muag tshuaj thiab kom lawv ua ke.
8. Muab koj tus kheej nrog 1-3 hom tshuaj insulin, koob txhaj tshuaj lossis koob txhaj tshuaj, qhov tseeb siv txawv teb lub ntsej muag thiab kuaj cov hlua rau nws.
9. Raws li cov ntaub ntawv sau ntau, xaiv cov tshuaj tua kab mob insulin - txiav txim seb koj xav tau cov tshuaj twg, lub sijhawm twg thiab siv sijhawm twg.
10. Kav tsij sau nws tus kheej rau tus kheej. Sij hawm dhau sijhawm, thaum cov ntaub ntawv sau ua ke, sau rau lub rooj hauv qab no. Xam kev txawv tsis tu ncua.

Txog cov xwm txheej uas cuam tshuam rau lub cev lub cev rau insulin, nyeem ntawm no. Nrhiav tawm kuj:

• Ntawm dab tsi cov ntsuas ntawm cov piam thaj hauv ntshav tau hais kom txhaj tshuaj insulin
• Qhov siab tshaj plaws ntawm cov tshuaj no rau cov neeg mob ntshav qab zib ib hnub
• Yuav siv cov insulin ntau npaum li cas rau 1 lub khob cij (XE) ntawm carbohydrates
• Ntau npaum li cas tsis muaj 1 koog ntawm cov tshuaj insulin txo cov piam thaj
• Yuav tsum muaj cov tshuaj hormones ntau npaum li cas los txo cov piam thaj li 1 mmol / l
• Yuav ua li cas lub sij hawm ntawm ib hnub yog zoo dua rau txhaj cov tshuaj insulin
• Qab zib tsis poob tom qab txhaj tshuaj: qhov ua tau

Puas tuaj yeem tswj hwm cov tshuaj insulin ntev ntev tau muab tso nrog yam tsis siv tshuaj luv thiab qhov quav?

Tsis txhob txhaj tshuaj ntau ntawm cov tshuaj insulin ntev ntev, vam tias yuav zam kom tsis muaj qab zib ntxiv tom qab noj mov. Ntxiv mus, cov tshuaj no tsis pab thaum koj xav tau sai txo qhov ntshav siab kom zoo siab. Ntawm qhov tod tes, cov tshuaj tiv thaiv luv-thiab luv-luv ua yeeb yam uas tau txhaj ua ntej noj zaub mov tsis tuaj yeem muaj qhov theem pib ruaj khov rau kev tswj cov metabolism hauv lub plab khoob, tshwj xeeb tshaj yog thaum tsaus ntuj. Koj tuaj yeem tau txais los ntawm ib qho tshuaj ib qho nkaus xwb hauv feem ntau tsis tshua mob ntshav qab zib.

Kev txhaj tshuaj insulin ib hnub ua ib zaug yog dab tsi?

Cov tshuaj uas siv tau ntev ntev Lantus, Levemir thiab Tresiba raug tso cai muab tshuaj ib hnub ib zaug. Txawm li cas los xij, Dr. Bernstein xav kom Lantus thiab Levemir txhaj tshuaj ib hnub ob zaug. Hauv cov neeg mob ntshav qab zib uas sim txhaj ib koob tshuaj tiv thaiv kab mob insulin no, kev tswj ntshav qab zib feem ntau tsis zoo.

Tresiba yog qhov tshiab tshaj tawm cov tshuaj insulin, txhua qhov kev txhaj tshuaj uas kav ntev txog 42 teev. Nws tuaj yeem muab pricked ib zaug ib hnub, thiab qhov no feem ntau muab cov txiaj ntsig zoo. Dr. Bernstein hloov mus rau Levemir insulin, uas nws tau siv rau ntau xyoo. Txawm li cas los xij, nws hno Treshiba insulin ob zaug ib hnub, raws li Levemir tau siv los txhaj. Thiab txhua lwm tus mob ntshav qab zib yog qhia kom ua ib yam.

Qee tus neeg mob ntshav qab zib sim hloov cov kev qhia ntawm cov tshuaj insulin sai ua ntej noj mov ntau zaus hauv ib hnub nrog rau ib hnub txhaj ib koob tshuaj ntau ntawm cov tshuaj ntev. Qhov no ua rau lub txiaj ntsig tsis zoo. Tsis txhob mus txoj kev no.

Nyeem yuav ua li cas tau txhaj tshuaj insulin. Thaum koj siv tus txheej txheem kev txhaj tshuaj lawm, nws yuav tsis muaj teeb meem ntau npaum li cas koj txhaj ib hnub koj ua. Kev mob los ntawm cov tshuaj insulin tsis yog ib qho teeb meem, nws yog qhov tsis muaj. Ntawm no kom kawm txhawm rau laij lub koob tshuaj yog - yog. Thiab tseem ntau tshaj ntawd, los muab koj tus kheej cov tshuaj muaj yeeb tshuaj zoo.

Cov sij hawm txhaj tshuaj thiab txhaj tshuaj insulin yuav tsum tau xaiv ib tus zuj zus. Txhawm rau ua qhov no, saib xyuas tus cwj pwm suab thaj hauv cov ntshav rau ob peb hnub thiab tsim nws txoj cai. Kev txiav siab ntawm lub cev yog kev txhawb nqa los ntawm kev tswj hwm ntawm insulin thaum lub sijhawm ntawd thaum nws tsis tuaj yeem tiv taus nws tus kheej.

Qee yam zoo ntawm cov tshuaj insulin sib tov yog dab tsi?

Dr. Bernstein tsis pom zoo kom siv cov khoom siv npaj txhij - Humalog Mix 25 thiab 50, NovoMix 30, Insuman Comb thiab lwm yam. Vim tias cov kev faib ua feem ntawm cov insulin ntev thiab ceev hauv lawv yuav tsis thooj txhij nrog qhov koj xav tau. Tus mob ntshav qab zib uas txhaj tshuaj sib tov nrog lawv tuaj yeem zam tsis dhau cov ntshav piam thaj. Siv ob qho tshuaj sib txawv rau tib lub sijhawm - txuas ntxiv thiab tseem luv lossis ultrashort. Tsis txhob ua tub nkeeg thiab tsis txuag nws.

Tseem Ceeb! Kev hno tib ntawm cov tshuaj insulin hauv kev txhaj sib npaug, coj rau ntau hnub, tuaj yeem ua ntau yam txawv. Lub zog ntawm lawv cov kev txiav txim yuav txawv los ntawm ± 53%. Nws nyob ntawm qhov chaw thiab qhov tob ntawm kev txhaj tshuaj, kev ua haujlwm ntawm cov ntshav qab zib, lub cev tso dej, qhov ntsuas kub thiab lwm yam. Hauv lwm lo lus, tib qho kev txhaj tshuaj tuaj yeem muaj txiaj ntsig me ntsis hnub no, thiab tag kis nws tuaj yeem ua rau cov ntshav qab zib tsawg.

Nov yog teeb meem loj. Tib txoj kev uas yuav zam nws yog hloov mus rau kev noj zaub mov kom tsawg, vim tias qhov xav tau ntawm cov tshuaj insulin yog txo los ntawm 2-8 zaug. Thiab qis dua cov koob tshuaj, qhov tsawg dua cov kev tawg ntawm nws qhov haujlwm. Nws tsis raug nquahu kom txhaj ntau dua 8 units hauv ib zaug. Yog tias koj xav tau cov koob tshuaj ntau dua, faib nws ua 2-3 qhov sib npaug ntawm qhov kev txhaj tshuaj.Ua lawv ib qho rau tom qab ib qho hauv lwm qhov chaw sib txawv, kom deb ntawm ib leeg, nrog tib lub koob txhaj tshuaj.

Yuav ua li cas tau txais cov tshuaj insulin ntawm kev lag luam nplai?

Cov kws tshawb fawb tau kawm ua kom Escherichia coli hloov kho hloov kho E. coli tsim cov tshuaj insulin uas tsim nyog rau tib neeg. Nyob rau hauv txoj kev no, ib lub tshuaj hormone los txo cov ntshav qab zib txij thaum xyoo 1970 los. Ua ntej lawv ua cov thev naus laus zis nrog Escherichia coli, cov neeg mob ntshav qab zib tau txhaj tshuaj rau lawv tus kheej nrog insulin los ntawm npua thiab nyuj. Txawm li cas los xij, nws txawv me ntsis ntawm tib neeg, thiab tseem muaj qhov tsis txaus ntseeg siab, vim qhov kev tiv thaiv kev ua xua ntau dhau thiab tsis haum. Cov tshuaj hormones los ntawm cov tsiaj tsis siv nyob rau sab hnub poob, hauv Lavxias Lavxias thiab lub teb chaws CIS. Cov tshuaj insulin niaj hnub no yog GMO khoom.

Qhov twg yog qhov zoo tshaj plaws insulin?

Nws tsis muaj lus teb rau cov lus nug no rau txhua tus neeg mob ntshav qab zib. Nws nyob ntawm tus kheej qhov yam ntxwv ntawm koj tus kab mob. Ntxiv mus, tom qab hloov mus rau kev noj zaub mov kom tsis muaj carb, insulin yuav tsum pauv hloov ntau. Cov koob tshuaj yuav raug txo kom tsawg thiab koj yuav xav kom hloov los ntawm ib cov tshuaj rau lwm qhov. Nws tsis pom zoo kom siv cov tshuaj nruab nrab Protafan (NPH), txawm tias nws tau pub dawb xwb, tab sis lwm yam tshuaj ntawm kev ncua ntev - tsis muaj. Cov laj thawj tau piav qhia hauv qab no. Kuj tseem muaj cov lus qhia txog cov hom tshuaj tiv thaiv ntev.

Rau cov neeg mob uas ua raws li cov zaub mov noj qis, noj cov tshuaj luv luv (Actrapid) zoo dua li cov tshuaj bolus insulin dua li noj mov ntau dua li cov luv luv. Cov khoom noj qis-carb yog nqus tau qeeb, thiab cov tshuaj ultrashort ua haujlwm sai. Qhov no hu ua kev txiav txim siab profile tsis sib xws. Nws tsis yog qhov yuav tsum tau txiav Humalog ua ntej noj mov, vim tias nws tsis tshua xav tau, ntau zaus ua rau cov piam thaj nce siab. Ntawm qhov tod tes, Humalog zoo dua li lwm tus pab ua kom cov qab zib ntau dua, vim tias nws pib ua kom nrawm dua li lwm hom ultrashort thiab, tshwj xeeb, luv luv insulin.

Dr. Bernstein muaj tus mob ntshav qab zib hom 1 ntau dhau los thiab tau tswj nws tau ntau tshaj 70 xyoo lawm. Nws siv 3 hom tshuaj insulin:

1. Txuas Ntxiv - Txog hnub, Tresiba yog qhov zoo tshaj plaws
2. Luv - rau kev txhaj tshuaj ua ntej noj mov
3. Ultrashort - diluted Humalog - rau qhov xwm txheej zoo thaum koj xav tau ceev nrooj cov ntshav qabzib sai sai

Tsawg tus neeg mob ntshav qab zib yuav xav tinker nrog peb cov tshuaj. Tej zaum qhov kev txiav txim siab zoo yuav raug txwv rau ob - txuas ntxiv thiab luv. Hloov ntawm luv luv, koj tuaj yeem sim ntaus NovoRapid lossis Apidra ua ntej noj mov. Tresiba yog qhov kev xaiv zoo tshaj plaws rau cov insulin ntev, txawm hais tias nws tus nqi siab. Vim li cas - nyeem hauv qab no. Yog tias muaj nyiaj txiag cia, siv nws. Cov tshuaj yeeb dej caw no tej zaum zoo dua li cov nyob hauv tsev. Qee leej ntawm cov tshuaj no nyob sib txawv rau txawv teb chaws, thiab tom qab ntawd nqa mus rau Lavxias Federation lossis CIS lub teb chaws thiab ntim rau ntawm qhov chaw. Thaum lub sijhawm tam sim no, tsis muaj ntaub ntawv qhia txog yuav ua li cas tus txheej txheem zoo li no cuam tshuam rau qhov zoo ntawm cov khoom tiav.

Kev npaj tshuaj insulin tsawg dua li cas yuav ua rau muaj kev tsis haum tshuaj?

Cov tshuaj hormones yog los ntawm cov txiav caj dab ntawm npua thiab nyuj feem ntau ua rau kev ua xua. Yog li ntawd, lawv tsis siv ntxiv lawm. Ntawm kev sab laj, qee tus mob ntshav qab zib yws yws yws tias lawv yuav tsum hloov insulin vim kev ua xua thiab tsis haum. Cov neeg zoo li no yuav tsum tau ua ntej ntawm txhua qhov mus noj zaub mov noj kom tsawg. Cov neeg mob uas txwv tsis pub muaj carbohydrates nyob rau hauv lawv cov zaub mov noj yuav tsum tau noj tsawg kawg. Kev ua xua, hypoglycemia, thiab lwm yam teeb meem tshwm sim tsawg dua nyob hauv lawv dua li cov uas txhaj koob tshuaj.

Tiag tiag cov tshuaj insulin tsuas yog siv yeeb tshuaj luv luv Actrapid NM, Humulin Tsis tu ncua, Insuman Rapid GT, Biosulin R thiab lwm yam. Txhua hom kev ncua ntev thiab kev ua haujlwm ntawm ultrashort yog analogues. Cov kws tshawb fawb me ntsis hloov lawv cov qauv los txhim kho lub zog. Cov lus piv txwv ua rau muaj kev tsis haum tshuaj tsis ntau dua li tib neeg lub cev insulin. Tsis txhob ntshai siv lawv.Muaj kev zam rau tsuas yog ua rau cov qog nruab nrab-hu ua protafan (NPH). Nws tau piav qhia nyob rau hauv cov ntsiab lus hauv qab no.

Cov Hom Ntev Ntev Insulin

Hom insulin ntev ntev tau tsim los ua kom cov qab zib ib txwm nyob ntawm lub plab khoob thaum nruab hnub, thiab thaum tsaus ntuj thaum pw. Cov txiaj ntsig ntawm kev txhaj tshuaj ntawm cov nyiaj no thaum hmo ntuj yog tswj hwm los ntawm theem ntawm cov piam thaj hauv cov ntshav thaum sawv ntxov tom ntej ntawm lub plab khoob.

Lub vas sab Endocrin-Patient.Com lub vev xaib txhawb qhov tsis yog-tab sis muaj kev kho mob zoo rau hom 2 thiab ntshav qab zib hom 1 tsim los ntawm Dr. Bernstein. Saib nws daim vis dis aus ntawm cov hom nrov ntawm insulin ntev.

Cov tshuaj piav qhia hauv qab no tsis pab ua kom cov ntshav qab zib sai sai, thiab kuj tsis yog npaj rau kev nqus ntawm cov carbohydrates thiab cov nqaijrog noj. Tsis txhob sim hloov cov tshuaj luv luv los yog ultrashort insulin txhaj tshuaj nrog qhov loj ntawm cov tshuaj ntev.

Txhawm rau tswj cov keeb kwm yav dhau los ntawm cov tshuaj insulin hauv cov ntshav, cov tshuaj nruab nrab (protafan, NPH) thiab kev ua yeeb yam ntev (Lantus thiab Tujeo, Levemir) yog siv. Tsis ntev los no, qhov ntev ntev tshaj tawm insulin Treshiba (degludec) tau tshwm sim, uas tau dhau los ua tus thawj coj vim nws cov khoom zoo dua. Saib cov lus hauv qab no yog cov lus qhia ntxiv.

Hom 2 ntshav qab zib insulin txoj kev kho mob ib txwm pib nrog kev txhaj tshuaj ntawm cov insulin txuas ntxiv. Tom qab ntawd, lawv tuaj yeem tso ntxiv ntau dua ntawm cov tshuaj tiv thaiv luv luv lossis ultrashort ua ntej noj mov. Feem ntau, cov kws kho mob tau sau ntawv rau cov neeg mob ntshav qab zib hom 2 ib koob tshuaj insulin ntev li ntawm 10-20 ib hnub lossis txiav txim siab pib noj raws li tus neeg mob lub cev qhov hnyav. Dr. Bernstein nquahu ib tug kheej ntxiv ib tug kheej. Nws yog ib qho tsim nyog los saib xyuas tus cwj pwm ntawm qab zib nyob rau hauv 3-7 hnub, ntsuas nws nrog glucometer. Tom qab ntawd, cov txheej txheem tshuaj insulin raug xaiv, ntsuas cov ntaub ntawv sau ua ke. Qhov no yog piav qhia ntau yam nyob rau sab saud.

Ntxiv rau cov tshuaj uas tau teev tseg hauv lub rooj, muaj ob peb hom kev tiv thaiv ib nrab-insulin. Dr. Bernstein tsis pom zoo kom siv lawv, tab sis koj yuav tsum paub txog lawv vim tias lawv nrov heev. Cov no yog Protafan HM, Humulin NPH, Insuman Bazal GT, Biosulin N thiab lwm yam. Lawv pib ua kwv yees li 2 teev tom qab txhaj tshuaj, muaj lub ncov tom qab 6-10 teev thiab tag nrho lub sijhawm yog 8-16 teev. Nruab nrab insulin feem ntau hu ua protafan. NPH sawv rau Hagedorn's Neutral Protamine. Qhov no yog cov tsiaj cov protein uas tau muab ntxiv kom qeeb rau kev nqis tes ua.

Vim li cas koj yuav tsum tsis txhob siv cov tshuaj protafan (NPH):

1. Hagedorn cov tshuaj tiv thaiv nruab nrab feem ntau ua rau ua xua.
2. Ntau tus neeg mob ntshav qab zib sai dua lossis ntev tom qab yuav tsum tau xoo hluav taws xob uas siv qhov nruab nrab los ntsuas xyuas cov hlab uas pub lub plawv. Hauv cov neeg mob uas tau txhaj cov tshuaj protafan, muaj kev fab tshuaj hnyav tshwm sim thaum kuaj mob no, feem ntau nrog kev tsis nco qab thiab tuag taus.
3. Cov neeg mob ntshav qab zib uas ua raws li cov zaub mov noj kom tsawg, feem ntau siv cov koob tshuaj insulin tsawg. Hauv cov koob tshuaj tsawg no, protafan kav tsis pub dhau 8-9 teev. Nws ploj lawm ib hmos thiab tag nrho ib hnub.

Nruab nrab insulin protafan (NPH) yuav tsum tsis txhob txhaj, txawm hais tias nws raug muab raws li cov tshuaj dawb, thiab lwm cov tshuaj yeeb ntev yuav tsum tau yuav koj cov nyiaj.

Cov tshuaj insulin twg zoo dua: Lantus lossis Tujeo?

Tujeo yog tib qho Lantus (glargin), tsuas yog nyob hauv kev ua kom muaj zog nce 3 zaug. Raws li ib feem ntawm cov tshuaj no, 1 koog ntawm ntev insulin glargine yog pheej yig dua li yog tias koj txhaj Lantus. Hauv txoj ntsiab cai, koj tuaj yeem txuag tau nyiaj yog tias koj hloov ntawm Lantus mus rau Tujeo tib lub koob.Cov cuab yeej no tau muag tag nrog cov yeeb yaj kiab uas yooj yim tshwj xeeb uas tsis tas yuav ntau dua kev hloov dua siab tshiab. Tus mob ntshav qab zib tsuas yog teev cov koob tshuaj uas yuav tsum tau siv hauv cov UNITS, tsis yog milliliters. Yog tias ua tau, nws zoo dua tsis txhob hloov ntawm Lantus mus rau Tujeo. Kev txheeb xyuas ntawm tus mob ntshav qab zib txog kev hloov pauv zoo li no feem ntau tsis zoo.

Txog hnub, qhov tshuaj insulin ntev tshaj plaws tsis yog Lantus, Tujeo lossis Levemir, tab sis cov tshuaj tshiab Tresib. Nws ua ntev dua li nws tus neeg sib tw. Siv nws, koj yuav tsum siv dag zog tsawg dua los tswj cov suab thaj ib txwm nyob rau thaum sawv ntxov ntawm lub plab khoob.

Treshiba yog ib qho tshuaj muaj pheej hmoo tshiab uas raug tus nqi 3 zaug kim dua li Lantus thiab Levemir. Txawm li cas los xij, koj tuaj yeem sim hloov mus rau nws, yog tias muaj nyiaj txaus. Dr. Bernstein hloov mus rau Tresib thiab txaus siab txog qhov tshwm sim. Txawm li cas los xij, nws tseem pheej nkaug nws 2 zaug hauv ib hnub, ib yam li Levemir tau siv ua ntej. Hmoov tsis zoo, nws tsis qhia qhov sib txawv ntawm koob tshuaj txhua hnub yuav tsum muab faib ua 2 koob. Tej zaum, feem ntau yuav tsum tau tswj hwm thaum yav tsaus ntuj, thiab ib qho me me yuav tsum tawm mus thaum sawv ntxov.

Dab tsi yog qhov sib txawv ntawm luv luv insulin thiab ultrashort?

Muab koob tshuaj ntawm cov tshuaj insulin luv luv pib ua tom qab 30-60 feeb. Nws qhov kev txiav txim tiav tag nrog 5 teev. Ultrashort insulin pib thiab xaus sai dua li luv. Nws pib txo cov ntshav qab zib hauv 10-20 feeb.

Actrapid thiab lwm yam tshuaj ntawm luv luv insulin yog daim ntawv qhia meej ntawm tib neeg lub cev. Cov lwg me me ntawm kev npaj ultrashort Humalog, Apidra thiab Novorapid hloov kho me ntsis piv rau tib neeg cov kua dej txhawm rau txhawm rau kom lawv ua tiav. Peb taw qhia tias cov tshuaj ultrashort ua rau ua xua tsis ntau tshaj li cov tshuaj insulin luv luv.

Puas yog nws tsim nyog los noj tom qab hno ntshav ntawm luv luv lossis ultrashort insulin?

Cov lus nug qhia tau hais tias koj tsis paub meej txog kev siv cov insulin ceev rau cov ntshav qab zib. Ua tib zoo nyeem tsab xov xwm “Muab xam los ntawm lub koob ntawm luv luv thiab ultrashort insulin”. Cov tshuaj muaj zog rau cov tshuaj insulin sai - qhov no tsis yog khoom ua si! Nyob rau hauv inept txhais tes, lawv muaj kev phom sij hauv ntiaj teb.

Raws li txoj cai, kev txhaj tshuaj ntawm luv luv thiab ultrashort insulin yog muab ua ntej noj mov kom cov zaub mov noj tsis nce ntshav qab zib. Yog tias koj txhaj insulin ceev thiab hla kev noj mov, qab zib yuav poob thiab cov tsos mob ntawm kev ua qog ntshav yuav tshwm sim.

Qee zaum cov neeg mob ntshav qab zib tau txhaj tshuaj rau lawv tus kheej nrog rau qhov tsis txaus siab sai kawg ntawm cov tshuaj insulin, thaum lawv cov ntshav qabzib dhia thiab lawv yuav tsum tau txo qis sai sai rau qhov ib txwm muaj. Hauv cov xwm txheej zoo li no, nws tsis tsim nyog noj tom qab kev txhaj tshuaj.

Tsis txhob txhaj tshuaj rau koj tus kheej, thiab txawm tias tsawg dua li ntawd, rau tus menyuam mob ntshav qab zib, luv lossis ultrashort insulin, txog thaum koj xam txoj kev yuav ua li cas rau nws cov tshuaj. Txwv tsis pub, muaj ntshav siab ntau, poob ntawm kev nco qab, thiab tseem muaj peev xwm tuag tau. Nyeem ntawm no nthuav dav txog kev tiv thaiv thiab kev kho mob ntshav qab zib kom tsawg.

Qhov twg cov insulin zoo dua: luv lossis luv luv?

Ultrashort insulin pib ua sai dua li luv. Qhov no ua rau cov neeg mob ntshav qab zib pib noj yuav luag tam sim ntawd tom qab txhaj, tsis tas ntshai tsam cov ntshav qab zib yuav dhia.

Txawm li cas los xij, insulin ultra-luv yog tsis zoo nrog lub siab-carb cov zaub mov noj. Tus kab mob ntshav qab zib no yog, tsis muaj exaggeration, miraculous. Tus mob ntshav qab zib uas hloov mus rau nws, nws zoo dua rau qhov nkag mus rau ib qho luv luv Actrapid ua ntej noj mov.

Nws yog qhov zoo tagnrho rau prick luv insulin ua ntej noj mov, thiab tseem siv ultrashort thaum koj xav tau kom sai nqa cov piam thaj siab. Txawm li cas los xij, hauv lub neej tiag tiag, tsis muaj ib qho ntawm cov neeg mob ntshav qab zib tuav peb hom insulin hauv lawv cov tshuaj kho mob hauv tib lub sijhawm. Tom qab tag nrho, koj tseem yuav tau siv tshuaj ntev. Xaiv nruab nrab ntawm insulin luv thiab ultrashort, koj yuav tsum ua kom muaj kev sib ceg.

Ntev npaum li cas nws yuav siv sij hawm mus txhaj tshuaj sai sai?

Raws li txoj cai, muab koob tshuaj ntawm luv luv lossis ultrashort insulin ceases zoo tom qab 4-5 teev. Ntau tus neeg mob ntshav qab zib tau txhaj tshuaj rau lawv tus kheej nrog insulin ceev, tos 2 teev, ntsuas kev qab zib, thiab tom qab ntawd ua rau lwm lub qhov ncauj.Txawm li cas los xij, Dr. Bernstein tsis pom zoo qhov no.

Tsis txhob cia ob lub koob txhaj tshuaj sai rau kev ua haujlwm ib txhij hauv lub cev. Saib xyuas qhov sij hawm luv li ntawm 4-5 teev ntawm kev txhaj tshuaj. Qhov no yuav txo qis ntau zaus thiab mob hnyav txhawm rau ua kom tsis muaj ntshav qab zib. Nyeem ntxiv txog kev tiv thaiv thiab kev kho mob ntshav qab zib nyob ntawm no.

Rau cov neeg mob uas muaj ntshav qab zib mob hnyav uas raug yuam ua luv luv lossis hno cov ntshav ua ntej noj mov, noj ntau 3 zaug hauv ib hnub thiab tswj hwm tshuaj hormone ua ntej noj mov. Ua ntej txhaj tshuaj, koj yuav tsum ntsuas koj cov piam thaj kom kho qhov koob tshuaj insulin.

Ua raws li tsoomfwv no, txhua lub sijhawm koj yuav nkag mus rau lub koob tshuaj insulin tsim nyog rau cov khoom noj, thiab qee zaum nce ntxiv kom txo tau cov suab thaj. Qhov koob tshuaj sai ntawm insulin uas yuav ua rau koj nqus cov khoom noj yog hu ua bolus zaub mov. Cov koob tshuaj uas yuav tsum tau ua kom cov ntshav qabzib feem ntau hu ua kev kho bolus.

Tsis zoo li cov zaub mov bolus, ib qho txhim kho bolus tsis yog tswj hwm txhua lub sijhawm, tab sis tsuas yog tsim nyog. Koj yuav tsum muaj peev xwm laij cov zaub mov kom raug thiab kho bolus, thiab tsis txhob txhaj ib koob ib zaug. Nyeem ntxiv hauv kab lus "Muab xam ntawm qhov luv ntawm luv luv thiab ultrashort insulin".

Txhawm rau kom muaj kev ncua sij hawm li 4-5 teev ntawm kev txhaj tshuaj, koj yuav tsum sim noj tshais thaum ntxov. Txhawm rau sawv nrog cov piam thaj ib txwm thaum sawv ntxov ntawm lub plab khoob, koj yuav tsum tau noj hmo tsis pub dhau 19:00. Yog tias koj ua raws li qhov kev pom zoo rau noj hmo thaum ntxov, tom qab ntawd koj yuav muaj qhov qab los noj mov zoo thaum sawv ntxov.

Cov neeg mob ntshav qab zib uas ua raws li cov zaub mov noj qis yuav tsum tau txhaj tshuaj insulin tsawg kawg, piv rau cov neeg mob uas raug kho raws li cov qauv kev cai. Thiab qis dua cov koob tshuaj insulin, qhov ntau lawv yuav ruaj khov thiab cov teeb meem tsawg.

Humalog thiab Apidra - qhov kev txiav txim ntawm insulin yog dab tsi?

Humalog thiab Apidra, nrog rau NovoRapid, yog hom insulin ultrashort. Lawv pib ua haujlwm nrawm dua thiab ua kom muaj zog dua li siv yeeb tshuaj luv luv, thiab Humalog sai dua thiab muaj zog dua li lwm tus. Cov npaj luv luv yog tib neeg cov insulin, thiab ultrashort yog hloov kho me ntsis. Tab sis qhov no tsis tas yuav tsum them sai sai. Txhua yam tshuaj luv thiab ultrashort muaj qhov tsis tshua muaj sib npaug ntawm kev ua xua, tshwj xeeb yog tias koj ua raws li cov zaub mov noj qis thiab prick lawv nyob rau hauv cov koob tshuaj qis.

Cov tshuaj insulin twg zoo dua: Humalog lossis NovoRapid?

Hais txog kev ntseeg nws tau ntseeg tias ultra-luv npaj Humalog thiab NovoRapid, nrog rau Apidra, ua nrog tib lub zog thiab nrawm. Txawm li cas los xij, Dr. Bernstein hais tias Humalog yog tus muaj zog dua li ntawm ob, thiab tseem pib ua kom sai dua me ntsis.

Tag nrho cov kev hais daws no tsis haum rau kev txhaj tshuaj ua ntej noj mov rau cov neeg mob ntshav qab zib uas ua raws li cov zaub mov noj qis. Vim tias cov zaub mov carb qis yuav nqus tau qeeb, thiab cov tshuaj ultrashort sai sai pib txo cov ntshav qab zib. Lawv cov tes hauj lwm profiles tsis sib haum. Yog li no, rau qhov kev yaum ntawm cov nqaijrog thiab carbohydrates, nws zoo dua yog siv cov tshuaj insulin luv luv - Actrapid NM, Humulin tsis tu ncua, Insuman Rapid GT, Biosulin R lossis lwm yam.

Ntawm qhov tod tes, Humalog thiab lwm yam tshuaj ultrashort ceev cov ntshav qab zib kom hnyav dua li cov luv. Cov neeg mob uas mob ntshav qab zib hom 1 ntau ntau yuav tsum siv 3 hom tshuaj insulin nyob rau tib lub sijhawm:

• Ncua
• Luv luv rau khoom noj
• Ultrashort rau cov xwm txheej ceev, ceev churning ntawm cov piam thaj.

Tej zaum muaj kev hais daws zoo yuav yog siv NovoRapid lossis Apidra ua kev kho mob thoob ntiaj teb es tsis txhob siv cov tshuaj Humalog thiab insulin luv.

16 lus hais txog "Hom insulin thiab lawv qhov kev txiav txim siab"

Nyob zoo Tav Kuv muaj hnub nyoog 49 xyoos, mob ntshav qab zib hom 1 pib 3 xyoo dhau los, qhov siab 169 cm, hnyav 56 kg. Nqe Lus Nug: Puas muaj kev kuaj ntshav uas ua rau kuv paub tseeb qhov twg ntawm cov tshuaj insulin Kuv yuav ua kom zoo ntxiv? Tsis ntev los no kuv hloov mus rau Protafan thiab Aktrapid, tab sis txhua qhov zoo ib yam, liab tseem nyob ntev rau ntawm qhov chaw txhaj tshuaj nrog ib tus xaum xim.

Puas muaj kev sim ntshav uas tso cai rau kuv kom paub qhov tseeb twg ntawm cov insulin Kuv yuav ua kom zoo ntxiv?

Tsis muaj kev ntsuam xyuas zoo li no. Kev npaj tshuaj insulin zoo tshaj yog xaiv los ntawm kev sim thiab qhov yuam kev.

hloov mus rau Protafan thiab Aktrapid, qhov liab tseem nyob ntev heev ntawm qhov chaw txhaj tshuaj nrog ib rab koob xaum.

Nws yog qhov zoo dua los hloov cov protafan nrog lwm qhov insulin ntev ntev. Nyeem ntxiv hauv kab lus.

Kuv muaj hnub nyoog 68 xyoo. Ntshav qab zib Hom 1, 40 xyoo ntawm kev paub. Nws yog hmoov tsis labile. Muaj cov nyom. Txaus siab heev rau Fiasp insulin. Kuv nug koj, qhia peb txog nws hauv kev nthuav dav raws li koj muaj peev xwm. Tam sim no kuv hloov mus rau Tresiba - Kolya, zoo li ua ntej Levemir. Cov txiaj ntsig tshwm sim tau zoo heev - thawj zaug nyob rau hauv lub sijhawm ntev. Noj cov zaub mov carbohydrate. Kuv muaj kev nyiam ketoacidosis thiab pib hloov raum, yog li kuv ntshai cov zaub mov tsis muaj carb ntau. Txawm hais tias zoo npaum li cas nrog qis GI tsis muaj peaks! Kuv zoo siab heev uas kuv pom koj lub xaib! Kuv yuav ntxiv: tam sim no kuv muaj bolus Humalog txij li xyoo 2001. Thiab cov so ntawm cov tshuaj ultra-luv tsis ua haujlwm. Kuv nyiam Akirapid - Kuv ua rau nws thaum kuv noj ntau yam txiv ntoo lossis nqaij, tsis tshua muaj heev. Nws tau dhau los ua nyuaj nrog nws.

Txaus siab heev rau Fiasp insulin. Thov qhia rau kuv txog nws nyob rau hauv kom meej.

Ultrashort insulin tsis zoo sib xws nrog kev noj haus qis-carb, yog li cov tshuaj no muaj qhov tsis txaus siab rau kuv. Hauv Lavxias tsis muaj ntaub ntawv hais txog nws, tab sis kuv tub nkees heev los khawb cov ntaub ntawv lus Askiv.

kev pib hloov hauv lub raum, yog li kuv ntshai cov zaub mov tsis zoo carb ntau

Nov yog koj qhov yuam kev loj. Koj tsis tas yuav ntshai, tab sis kuaj ntshav thiab tso zis ntsuas uas kuaj ntshav raum ua haujlwm. Nyeem ntxiv ntawm no - http://endocrin-patient.com/diabet-nefropatiya/. Raws li kev soj ntsuam los ntawm cov kev ntsuam xyuas no, koj tuaj yeem txiav txim siab meej tias seb qhov khoom noj qis rau cov zaub mov qis rau koj lossis yog koj twb tsis dhau lub tsheb ciav hlau.

Kuv zoo siab heev uas kuv pom koj lub xaib!

Rau cov neeg mob ntshav qab zib uas tsis hloov mus rau Dr. Bernstein txoj kev noj haus, tag nrho cov ntaub ntawv no tsis muaj qab hau.

Tam sim no kuv hloov mus rau Tresiba - Kolya, zoo li ua ntej Levemir. Cov txiaj ntsig tshwm sim tau zoo heev - thawj zaug nyob rau hauv lub sijhawm ntev.

Cov ntaub ntawv no muaj txiaj ntsig. Kev txheeb xyuas txog cov tshuaj Tresib los ntawm cov neeg mob Lavxias-hais lus tseem tsis txaus. Koj cov lus kuj muaj txiaj ntsig rau coob leej.

Nyob zoo Kuv muaj 15 xyoos, tau raug kev mob ntshav siab hom 1 txij li lub caij ntuj sov dhau los. Qab zib jumps ntawm 3-4 txog 9-11 mmol / l. Kuv tau yuam kev tau mus rau koj lub xaib, dhau los ua kev txaus siab thiab tam sim no kuv kawm rau ob peb teev hauv ib hnub. Tom qab pib kho mob hauv tsev kho mob, kuv lub cev qhov hnyav nce ntau. Tam sim no kuv qhov hnyav yog 78 kg nrog qhov siab ntawm 167 cm. Kuv sim noj cov zaub mov ntuj thiab txav ntau dua, tab sis nws yuav luag tsis pab. Hmoov tsis zoo, Kuv feem ntau so ntawm kev noj qab haus huv. Qhov kev noj zaub mov kom tsawg los ntawm lub cev yuav pab kuv yuag? Kuv ntshai tias nws yuav cog raum. Puas yog nws muaj tseeb tias insulin cuam tshuam rau qhov hnyav nce los ntawm kev hloov cov piam thaj rau hauv cov rog? Qhov koj sau nws txawv heev ntawm cov ntaub ntawv ntawm lwm lub xaib. Qhia rau kuv seb yuav noj dab tsi thiab noj dab tsi tam sim no? Dab tsi ntawm kev ua kis las zoo dua rau kev ua? Nws puas tuaj yeem txo qhov koob tshuaj insulin? Thiab yog tias muaj, ntau npaum li cas? Cov tshuaj acetone tuaj yeem tshwm sim thaum lub cev poob? Lwm lo lus nug: huab cua hloov li cas feem ntau cuam tshuam rau cov neeg mob ntshav qab zib?

Puas yog nws muaj tseeb tias insulin cuam tshuam rau qhov hnyav nce los ntawm kev hloov cov piam thaj rau hauv cov rog?

Yog lawm, qhov no yog ib qho ntawm nws cov yeeb yam hauv lub cev.

Kev noj zaub mov kom tsawg los yuav pab kuv yuag?

Hauv txoj ntsiab cai, koj tsis muaj lwm txoj kev xaiv kom poob phaus yam tsis muaj kev phom sij rau kev noj qab haus huv, tsuas yog hloov mus rau kev noj zaub mov kom tsawg thiab ua kom txo qis hauv cov tshuaj insulin.

Qee zaum cov neeg mob ntshav qab zib, nrog lub hom phiaj poob phaus, txo cov tshuaj insulin los ntawm kev nti qaub ncaug rau lawv cov ntshav qab zib. Qhov tau txais kev puas tsuaj loj heev.

Nws puas tuaj yeem txo qhov koob tshuaj insulin? Thiab yog tias muaj, ntau npaum li cas?

Cov neeg mob uas muaj ntshav qab zib hom 1 tuaj yeem noj tsis ntau tshaj 30 g ntawm carbohydrates ib hnub: 6 g rau pluas tshais, 12 g rau pluas su thiab noj hmo, tsuas yog los ntawm cov zaub mov pub, nrog rau kev zam txhua yam khoom noj uas txwv tsis pub.

Tom qab hloov mus rau txoj kev noj haus ntawm Dr. Bernstein, cov tshuaj insulin raug txo tsawg kawg 2 zaug, feem ntau 5-7 zaug. Nyob rau tib lub sijhawm, cov qib piam thaj hauv cov ntshav tsis nce ntxiv, tab sis normalizes, nws cov jumps poob qis.

Qhov koj sau nws txawv heev ntawm cov ntaub ntawv ntawm lwm lub xaib.

Koj tseem tsis tau ntseeg tias kev siv ntawm cov tswv yim pom zoo yog kev siv tsawg?

Cov tshuaj acetone tuaj yeem tshwm sim thaum lub cev poob?

Tau, thiab tsis muaj dab tsi yuav tsum tau ua kom tiav txog qhov no. Ntsuas koj cov piam thaj ntau dua thiab khaws cia hauv qab 9.0 mmol / L. Pin insulin yog tias tsim nyog kom cov qib piam thaj nyob hauv thaj tsam no. Haus dej kom ntau. Thiab nws yog qhov zoo dua tsis ntsuas ntsuas acetone txhua, yog li kom tsis txhob txhawj txog cov khoom ruam.

Huab cua hloov pauv feem ntau cuam tshuam li cas rau cov neeg mob ntshav qab zib?

Dab tsi ntawm kev ua kis las zoo dua rau kev ua?

Saib http://endocrin-patient.com/diabet-podrostkov/. Qhov kev xaiv ntawm kev ua kis las yog txiav txim siab. Kev ua neej nyob tsis muaj pa tsis ua hauj lwm ib yam li haus luam yeeb 10-15 luam yeeb ib hnub.

Nyob zoo Kuv yog 51 xyoo. Qhov siab yog 167 cm, hnyav yog 70 kg. Kuv muaj tus mob ntshav qab zib hom 1 tau ntau xyoo. Kohl Insuman Sai thiab Lantus. Yog tias koj mus koom nrog kev noj zaub mov kom tsawg, ntau npaum li cas lub sijhawm ua ntej noj mov koj yuav tsum txhaj Insuman Rapid? Tom qab noj mov tag, yuav coj li cas? Taug kev lossis so? Ua tsaug ntau ntau ua ntej. Kuv muaj kev cia siab.

Kuv yuav tsum tau muaj sijhawm ntau npaum li cas rau kev txhaj tshuaj Insuman Rapid ua ntej noj?

Zoo li lwm yam luv luv insulin, saib cov ntsiab lus hauv tsab xov xwm uas koj tau sau ntawv tawm tswv yim.

Tom qab noj mov tag, yuav coj li cas? Taug kev lossis so?

Taug kev yuav twv yuav raug hu tsis mob :).

Nyob zoo Kuv muaj hnub nyoog 68 xyoo. Kuv tau raug mob ntshav qab zib hom 2 txij li kuv muaj hnub nyoog 45 xyoos.
Tus kws kho mob ib txwm sau ntawv siv tshuaj dawb dawb rau nruab nrab: Humulin NPH lossis Rinsulin NPH. Kuv txawb nws 2 zaug ib hnub nyob rau thaum sawv ntxov thiab yav tsaus ntuj rau 18 units. Qab zib tiv thaiv keeb kwm yav dhau los yog 11-13.
Ib zaug, thaum tsis muaj ib nrab tshuaj insulin, lawv muab Levemir rau Lub Plaub Hlis. Tsis ntev los no pom koj lub xaib, tam sim no kuv sim ua raws li kev noj haus cov zaub mov tsis muaj ntsev ntau. Nws yog qhov nyuaj rau kev hloov pauv, tab sis kuv sim ua. Tawm tsam no keeb kwm ntawm khoom noj khoom haus thiab kev txhaj tshuaj, Levemir qab zib poob qis rau 7-8. Tus neeg mob cov qog ntshav qab zib tsawg tsawg.
Tam sim no tus kws kho mob sau ib daim ntawv ntxiv rau ib nrab insulin xwb. Thiab Levemir hauv khw muag tshuaj yog kim heev rau kuv - 3500 rubles. Qhia rau kuv, pes tsawg zaus koj yuav xav tau txhaj tshuaj insulin nruab nrab tam sim no?

Qhia rau kuv, pes tsawg zaus koj yuav xav tau txhaj tshuaj insulin nruab nrab tam sim no?

Hmoov tsis zoo, kev coj ua qhia pom tias cov insulin nruab nrab tsis tuaj yeem tswj hwm tus mob ntshav qab zib tau zoo. Xav txog yuav ua li cas kom tau txais cov tshuaj ntau dua niaj hnub no.

Nyob zoo Ua tsaug rau cov ntaub ntawv zoo li no! Peb tig mus rau zaub mov noj qes dua, kawm koj cov lus. Txiv (62 xyoo) muaj mob ntshav qab zib hom 2 nrog rau muaj teeb meem. Muaj 2 lub plawv mob plawv, mob hlab ntsha hlwb, thiab nyuam qhuav dhau los, muaj mob txha caj qaum. Kev phais mob rov qab, purulent epiduritis. Yuav luag ib hlis txij li thaum mob stroke ntawm pob txha caj qaum thiab phais qaum, tag nrho lub cev hauv qab txoj hlab ntaws tau tuag tes tuag taw, tseem nyob hauv tsev kho mob. Raws li cov lus qhia ntawm nws tus kws kho mob endocrinologist, Txiv tau tso 18 xim ntev ntawm Rosinsulin P thaum sawv ntxov thiab yav tsaus ntuj, nrog rau 8 ntu ntawm Rinsulin NPH ua ntej noj mov 3 zaug hauv ib hnub. Thov qhia rau peb txog cov tshuaj no. Koj puas qhia lawv lossis hloov ntawm lawv mus rau lwm tus? Txiv cov piam thaj hauv thaj av tseem ntau - 13-16, tab sis tej zaum qhov no yog vim muaj kev ua haujlwm tsis ntev los no. Peb yuav tsum muaj suab thaj kom qis. Yuav ua li cas rau cov tshuaj insulin?

txiv tso 18 units ntawm ntev Rosinsulin P thaum sawv ntxov thiab yav tsaus ntuj, nrog rau 8 pawg ntawm Rinsulin NPH ua ntej noj mov 3 zaug hauv ib hnub. Thov qhia rau peb txog cov tshuaj no.

Kev npaj tshuaj insulin hauv zos yog qhov zoo tshaj plaws zam.

Peb yuav tsum muaj suab thaj kom qis. Yuav ua li cas rau cov tshuaj insulin?

Koj tuaj yeem sim cov tshuaj txawv teb, tshwj xeeb yog tias koj tuaj yeem tau txais lawv dawb.

Txiv (62 xyoo) muaj mob ntshav qab zib hom 2 nrog rau muaj teeb meem. Muaj 2 lub plawv mob plawv, mob hlab ntsha hlwb, thiab nyuam qhuav dhau los, muaj mob txha caj qaum. Kev phais mob rov qab, purulent epiduritis. Yuav luag ib hlis txij li thaum mob stroke ntawm pob txha caj qaum thiab phais qaum, tag nrho lub cev hauv qab ntaws yog tuag tes tuag taw

Kuv ntshai koj lub tsheb ciav hlau twb tawm mus lawm. Tswj ntshav qab zib ib txwm ua kom muaj kev rau siab ntau. Kuv tsis paub tseeb tias qhov no yuav yog qhov txiaj ntsig rau koj.

Nyob zoo Kuv niam, tom qab mob stroke, yog tus neeg tsis taus ntawm pab pawg 1, txav tsis taus nws tus kheej. Tiav los. Qhov hnyav 90 kg nrog kev loj hlob ntawm 156 cm. Actrapid tau raug tshaj tawm 3 zaug ib hnub ua ntej noj mov, tab sis nws tsis txo cov piam thaj rau cov lej ib txwm ua ntxiv lawm. (Txwm 6 xyoo) Tsis ntev los no hauv tsev kho mob muab tshuaj yaug R lossis biosulin R. Qab Zib khaws 11-12.Thiab txhua lub hlis peb hloov pauv nrog insulin - lawv tau muab dab tsi tam sim no hauv tsev kho mob chaw, thiab muaj cov yaug tshuaj, lossis biosulin, lossis actrapid. Tsis ntev los no lawv txawm muab cov tshuaj biosulin H thiab raug hais kom txhaj li qub. Kuv paub tias qhov no yog insulin thaum nruab nrab, tab sis lawv tau hais rau kuv tias tsis muaj lwm yam tshuaj insulin dawb tam sim, noj, lawv muab rau. Teb rau kuv cov lus tsis txaus siab tias cov piam thaj muaj ntau, txawm tias kev noj haus thiab kev txhaj tshuaj kom raws sijhawm, Rinsulin NPH tau sau ntawv rau peb thiab tau hais kom txhaj thaum hmo ntuj thaum 11 teev tsaus ntuj thiab tsis noj mov ntxiv lawm. Kuv sim nyeem txhua yam hais txog kev kho mob ntshav qab zib thiab mob ntshav qab zib, thiab kuv xav tias txog sijhawm rau kuv tsum tsis muaj kev cia siab rau peb lub tsev kho mob, xa kuv niam mus rau cov tshuaj tuaj yuav thiab yuav kuv tus kheej. Kuv xav tias yuav luv luv insulin ua ntej noj mov thiab ib qho ntev rau yav hmo ntuj, tab sis kuv tsis tuaj yeem txiav txim siab xaiv nws tus kheej. Thov pab.

Kuv xav tias nws txog sijhawm rau kuv tsum tsis cia siab rau peb lub tsev kho mob, xa kuv niam mus rau cov tshuaj kom kuv tus kheej

Qhov no tsis yog thawj xyoo kuv tau saib xyuas cov xwm txheej zoo li no. Koj yuav tsum tso nws ib yam li nws thiab. Lub tsheb ciav hlau twb tawm lawm. Kev kho mob nquag yuav tsuas ua rau koj niam tsis muaj kev txom nyem.

Ua zoo saib xyuas koj tus kheej yog tias koj tsis xav ua kom rov ua li txoj hmoo ntawm niam. Koj muaj txoj hmoov tsis zoo.

Nyob zoo Kuv lub npe hu ua Konstantin. 42 xyoos. Ntshav qab zib Hom 2 yog hnub nyoog 15 xyoos. Thaum xub thawj nws haus tsuas yog Siofor, ob ntsiav tshuaj ntawm 850 tauj ib hnub, tom qab ntawd Galvus thiab lwm 1000 mg ntawm metformin tau ntxiv. Hauv rau lub hlis tom qab no, qab zib tsis tau poob qis. Lantus tau pauv mus rau cov kua dej hauv 8 pawg ua ntej yuav mus pw thiab ntxiv rau cov ntsiav tshuaj. Tseem siab qab zib thaum sawv ntxov. Ntawm ib ncig 15 tej zaum. Kuv tsis tsim txom cov khoom tsis raug txwv. Kuv tsis noj qab zib txhua. Kuv ua kis las, tab sis tsis tas li. Koj tuaj yeem pom zoo kom txo cov suab thaj li cas? Qhov siab 182 cm, hnyav 78 kg.

Koj tuaj yeem pom zoo kom txo cov suab thaj li cas?

Nyeem lub xaib no kom zoo thiab ua tib zoo ua raws li cov lus pom zoo. Yog hais tias, ntawm chav kawm, koj xav nyob.