Cov qauv ntawm cov ntsiav tshuaj Ariescore

Ariescore (tshuaj noj) Ntsuam xyuas: 9

Chaw tsim tshuaj paus: Ozone (Russia)
Cov Ntawv Tso Tawm:

Tab. 10 mg, 20 pcs., Nqe txij li 372 rubles
Tab. 20 mg, 20 pcs., Nqe txij li 510 rubles

Cub cub cov nqi hauv cov khw muag tshuaj online
Cov lus qhia rau kev siv

Cov tshuaj no yog tsim nyob rau hauv Russia, npaj rau kev kho mob ntawm cov kab mob ntawm cov hlab plawv system. Cov tshuaj phiv yog simvastatin hauv ib qho li 10 lossis 20 mg rau ib ntsiav tshuaj. Contraindicated nyob rau hauv lub hnub nyoog ntawm 18 xyoo.

Analogs ntawm cov tshuaj Ariescor

Cov analogue yog pheej yig dua los ntawm 313 rubles.

Chaw tsim tshuaj paus: Vertex (Russia)
Cov Ntawv Tso Tawm:

Ntsiav tshuaj 10 mg, 15 pcs., Nqe los ntawm 59 rubles
Ntsiav tshuaj 10 mg, 30 pcs., Nqe txij li 62 rubles

Tus nqi Simvastatin hauv khw muag tshuaj online
Cov lus qhia rau kev siv

Simvastatin yog lipid-txo qis tshuaj ntawm Lavxias teb sab tsim khoom. Nws muaj nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj thiab muaj tib cov tshuaj nquag hauv qhov ntau npaum li 10 txog 40 mg. Qhia rau siv nyob rau hauv kev kho mob ntawm cov kab mob ntawm cov hlab plawv system.

Cov analogue yog pheej yig dua los ntawm 173 rubles.

Chaw tsim tshuaj paus: Krka (Slovenia)
Cov Ntawv Tso Tawm:

Ntsiav tshuaj 20 mg, 14 pcs., Nqe los ntawm 199 rubles
Ntsiav tshuaj 10 mg, 28 pcs., Nqe los ntawm 289 rubles

Cov nqi Vasilip hauv cov khw muag tshuaj online
Cov lus qhia rau kev siv

Ntau muaj txiaj ntsig Slovenian hloov pauv nrog tib daim ntawv tso tawm thiab txheej txheej ntawm cov tshuaj yeeb dej caw. Cov cim tseem ceeb rau kev siv: thawj hypercholesterolemia los yog sib xyaw dyslipidemia, ib qho kev txo qis hauv cov hlab plawv tuag thiab kev mob hlwb hauv cov neeg mob uas tau soj ntsuam cov kab mob atherosclerotic mob plawv lossis ntshav qab zib mellitus. Muaj cov contraindications.

Cov analogue yog pheej yig dua los ntawm 265 rubles.

Chaw tsim tshuaj paus: Kide-oo Richter (Romania)
Cov Ntawv Tso Tawm:

Tab. 10 mg, 14 pcs., Nqe txij li 107 rubles
Tab. 10 mg, 28 pcs., Nqe txij li 202 rubles

Cov nqi Simvastol hauv cov khw muag tshuaj online
Cov lus qhia rau kev siv

Simvastol yog ib qho khoom lag luam ntawm Romanian ntau lawm. Muaj nyob hauv cov thawv ntawv cardboard ntawm 14 thiab 28 ntsiav tshuaj. Cov tshuaj ua haujlwm tau zoo ib yam nyob ntawm no, yog li cov lus qhia rau kev siv tsuas muaj qhov sib txawv me. Ua ntej pib kev kho mob, peb xav kom sab laj nrog kws kho mob.

Tso tawm daim ntawv thiab muaj pes tsawg leeg

Dosage daim Ovenkor tso tawm - cov ntsiav tshuaj uas muaj xim: dawb, puag ncig biconvex (10 lossis 30 pcs. Hauv cov hlwv, hauv ib daim ntawv thawv ntawm lub thawv 10, 20, 40, 60, 80 thiab 100 pob, 10, 14, 20, 28, 30, 40, 50 lossis 100 pcs. Hauv polymer ntim, hauv ib thawv ntawv tuab 1 thawv).

Composition 1 ntsiav tshuaj:

cov tshuaj nquag: simvastatin - 10 lossis 20 mg,
Cov khoom siv pabcuam: polyethylene glycol-4000, talc, titanium dioxide, castor roj, butyl hydroxyanisole, microcrystalline cellulose, ascorbic acid, lactose, citric acid, pob kws thiab pregelatinized starch rog, magnesium stearate, hydroxypropyl methylcellulose.

Cov Tshuaj Hauv Tshuaj

Cov tshuaj los ntawm cov pab pawg ntawm statins, muaj lipid-txo cov nyhuv, inhibits HMG-CoA reductaseCov. Nws cov qauv muaj kaw lactone nplhaib, uas yog hydrolyzed nyob rau hauv tib neeg lub cev, uas yog, nws yog ib tug prodrug.

Lactone nplhaib statins muaj kev nyiam rau lub enzyme HMG-CoA reductaseraws li qhov tshwm sim ntawm qhov uas nws ua kev sib tw khi rau ib feem ntawm cov receptor coenzyme Anyob qhov twg no enzyme hniav.

Ib feem ntawm cov qauv hluav taws xob (statin molecule) tau koom nrog hauv kev hloov pauv hydroxymethylglutarate hauv mevalonateuas cuam tshuam rau cov khoom lag luam ntawm kev sib txuas lus nruab nrab ntawm ib lub molecule rojCov. Cov txheej txheem no ua rau ntau cov kev hloov pauv, uas ua rau lub ncauj lus nkag mus ntxaws roj txo qis thiab ceev cov roj cholesterol catabolism LDLCov. Cov lipid-txo cov nyhuv ntawm cov tshuaj yog vim tias qhov txo qis hauv cov roj (cholesterol) tag nrho vim tias cov roj (cholesterol) LDLCov. Nyob rau tib lub sijhawm, txo qis hauv theem ntawm LDL koob tshuaj-siv thiab yog exponential.

Statins tsis cuam tshuam rau catabolism thiab kev sib txuas ntawm cov rog dawb, yog li lawv cuam tshuam rau theem ntawm TG tsis ncaj qha (thib ob). Raws li kev tshawb nrhiav, cov tshuaj nce qib qib ntawm HDL roj nce txog 14%. Ntxiv nrog rau qhov lipid-txo cov teebmeem, cov tshuaj muaj cov txiaj ntsig zoo ntawm lub vascular phab ntsa thaum lub sijhawm endothelial tsis ua haujlwm (ib qho cim ntawm preclinical manifestation ntawm atherosclerosis thaum ntxov), normalizes rheological cov yam ntxwv ntawm cov ntshav, thiab muaj antiproliferative thiab antioxidant nyhuv. Txoj kev kho nrog cov tshuaj yog nrog los ntawm kev txo qis hauv lub zaus ntawm cov kev mob plawv.

Cov Tshuaj Pharmacokinetics

Simvastatin muaj qhov nqus siab. Qhov siab tshaj plaws hauv cov ntshav ntshav tom qab noj tau tiav tom qab kwv yees li 1.3-2.4 teev, tom qab 12 teev nws txo qis txog 90%. Kev sib txuas lus nrog cov protein ntshav yog kwv yees li 95%.

Nws muaj cov nyhuv ntawm thawj kev nkag mus rau ntawm daim siab: hydrolysis nrog kev tsim ntawm active derivative beta-hydroxyacid, thiab lwm yam kev nquag thiab tsis muaj zog metabolites kuj tau pom.

Kev tshem tawm ib nrab-lub neej ntawm cov metabolites nquag yog 1.9 teev.

Nws yog tawm hauv feem ntau hauv daim ntawv ntawm cov roj ntsha nrog quav (60%). Hauv daim ntawv tsis ua haujlwm, kwv yees li 10-15% yog raug tawm los ntawm lub raum.

Kev ntsuas rau siv

hypercholesterolemia: thawj hypercholesterolemia (hom IIa thiab IIb) nyob rau hauv cov neeg mob uas muaj kev pheej hmoo ntawm kev txhim kho mob rau cov ntshav atherosclerosis nyob rau hauv cov xwm txheej tsis zoo kev noj zaub mov zoo nrog cov roj (cholesterol) thiab lwm yam kev ntsuas tsis siv tshuaj (poob ceeb thawj thiab kev siv lub cev), kev sib xyaw ntawm hypercholesterolemia thiab hypertriglyceridemia, uas tsis tshwj xeeb hloov kho. thiab lub cev ua si,
IHD (mob plawv): txhawm rau tiv thaiv myocardial infarction, txo kev pheej hmoo ntawm cov hlab plawv tsis zoo (mob hlab ntsha los yog lub cev ischemic tawm tsam), kev tuag, cov txheej txheem hauv lub plawv, nrog rau ua kom qeeb kev txhim kho ntawm cov hlab ntsha txhaws.

Cov Yuav Tsum Muaj

mob siab tus kab mob nyob rau theem nquag, nce ntxiv hauv cov kev ua haujlwm ntawm daim siab enzymes ntawm cov keeb kwm tsis paub,
porphyria
mob hlwb
hnub nyoog txog 18 xyoo
cev xeeb tub thiab lactation,
tsis pub ib tus neeg nkag rau ib qho twg ntawm cov tshuaj, nrog rau lwm cov tshuaj statin (HMG-CoA reductase inhibitors) hauv keeb kwm.

Tus Txheeb Ze (Ovenkor raug tsa los ntawm kev saib xyuas mob):

haus ntau dhau
arterial hypotension, cov kab mob sib kis mob hnyav, mob endocrine / metabolic tsis txaus, dej tsis haum, raug mob, kev phais mob (suav nrog kev kho hniav) lossis lwm yam mob uas yuav muaj kev loj hlob ntawm lub raum tsis ua haujlwm,
tej yam mob tom qab hloov khoom nruab nrog cev thaum txhaj tshuaj tiv thaiv kab mob (cuam tshuam nrog kev pheej hmoo ntawm lub raum tsis ua haujlwm thiab rhabdomyolysis),
qaug dab peg
txo qis / nce lub suab ntawm cov pob txha pob txha ntawm cov keeb kwm tsis paub.

Cov lus qhia rau kev siv Ovenkor: txoj kev thiab ntau npaum li cas

Qhov cub tau noj qhov ncauj 1 zaug hauv ib hnub nyob rau yav tsaus ntuj, ntxuav tawm nrog dej kom ntau. Lub sijhawm ntawm kev noj tshuaj yuav tsum tsis cuam tshuam nrog kev noj mov.

Ua ntej pib siv Ovenkor, tus neeg mob tau sau tshuaj noj rau cov zaub mov hypocholesterol, uas yuav tsum tau ua raws li thoob plaws hauv kev kho mob.

Nrog hypercholesterolemia, koob tshuaj txhua hnub nws txawv ntawm 10-80 mg.

Qhov pom zoo kom pib siv tshuaj rau hypercholesterolemia yog 10 mg. Qhov siab tshaj plaws - 80 mg ib hnub twg. Cov kev hloov (xaiv) ntawm koob tshuaj yuav tsum tau nqa tawm ntawm lub sijhawm 4 lub lis piam. Feem ntau, qhov pom qhov zoo yog pom thaum noj cov tshuaj hauv ib hnub tshuaj txog 20 mg.

Nrog homozygous cov kab mob hypercholesterolemia, Ovencor feem ntau yog muaj 40 mg rau hauv 1 koob tshuaj lossis 80 mg hauv 3 koob (20 mg thaum sawv ntxov thiab yav tav su, 40 mg thaum yav tsaus ntuj).

Kev siv tshuaj zoo ntawm Ovenkor rau kev ua kom mob plawv lossis muaj qhov pheej hmoo ntawm nws txoj kev loj hlob yog 20-40 mg rau ib hnub. Thaum pib ntawm txoj kev kho, 20 mg feem ntau yog hais tseg, cov koob tshuaj yuav tau nce nrog qhov so ntawm 4 lub lis piam. Thaum cov ntsiab lus LDL tsawg dua 75 mg / dl (1.94 mmol / L) thiab tag nrho cov roj (cholesterol) qis dua 140 mg / dl (3.6 mmol / L), qhov koob tshuaj txo.

Hauv qhov siab tshaj plaws ntawm 10 mg, Ovencor tau sau tsawg dua 30 ml / min hauv cov neeg mob uas mob raum tsis zoo (CRF) (creatinine tshem tawm) lossis kev kho ua ke nrog cyclosporine, danazole, gemfibrozil lossis lwm yam tshuaj fiber (tshwj tsis yog fenofibrate), niacin hauv lipid txo qis ( txog li 1000 mg rau ib hnub). Nrog rau kev siv tib lub sijhawm nrog amiodarone lossis verapamil, cov tshuaj Ovenor niaj hnub yuav tsum tsis pub tshaj 20 mg.

Sab sij huam

lub plab zom mov: mob plab, cem quav / raws plab, pom tsis txaus, xeev siab, pancreatitis, mob siab, ntuav, nce kev ua haujlwm ntawm daim siab enzymes, alkaline phosphatase thiab CPK (creatine phosphokinase),
kev ntxim siab rau cov plab hnyuv siab raum thiab cov hlab ntsha hauv lub cev: mob taub hau, asthenic syndrome, peripheral neuropathy, kiv taub hau, pw tsis tsaug zog, mob caj dab, mob nqaij ntshiv, ua txhaum cai ntawm saj tsis hnov qab, qhov muag plooj,
txhaj tshuaj tiv thaiv kab mob thiab ua xua: ua kub ntxhiab, eosinophilia, hyperemia ntawm daim tawv nqaij, mob caj dab, vasculitis, angioedema, polymyalgia rheumatism, thrombocytopenia, nce ESR, thim rov qab tshuaj lupus-zoo li syndrome, kub cev, urticaria, photosensitivity, ua tsis taus pa,
dermatological tshua: tsis tshua muaj - dermatomyositis, tawm pob ntawm daim tawv nqaij, alopecia, khaus,
musculoskeletal system: tsis muaj zog, myopathy, mob leeg, myalgia, tsis tshua muaj - rhabdomyolysis,
lwm cov kev cuam tshuam: palpitations, anemia, qis potency, mob raum tsis ua haujlwm.

Noj ntau dhau

Muaj tsis muaj cov tsos mob tshwj xeeb ntawm kev noj ntau dhau ntawm Ovenkor (cov neeg mob ntawm kev noj tshuaj hauv ib koob ntawm 450 mg yog paub).

Kev Kho Mob: kev ntsuas tswj kom txo qis kev nqus ntawm qhov tshuaj (ua rau ntuav, noj hluav ncaig hluav taws xob), muaj kev kho mob raws li kev tswj hwm lub raum thiab hepatic muaj nuj nqi, thiab ntshav qib CPK.

Nyob rau hauv cov ntaub ntawv ntawm kev loj hlob ntawm myopathy nrog rhabdomyolysis thiab mob raum tsis ua haujlwm (qhov kev txhaum yog qhov tsawg, tab sis tuaj yeem tshwm sim rau hauv daim ntawv loj), Ovenkor yog tam sim ntawd tso tseg, kev tswj hwm ntawm diuretic thiab sodium bicarbonate yog qhia (los ntawm kev tso ntshav ntawm leeg). Yog tias tsim nyog, kev kho mob hemodialysis tau ua tiav.

Rhabdomyolysis tuaj yeem ua rau hyperkalemia, uas raug tshem tawm los ntawm kev tswj hwm cov tshuaj calcium chloride lossis calcium gluconate, qabzib infusion hauv kev ua ke nrog insulin, potassium ion pauv, lossis, nyob rau hauv loj heev, los ntawm hemodialysis.

Cov lus qhia tshwj xeeb

Thaum pib ntawm kev kho, kev hloov pauv hauv qib hauv lub siab enzymes yuav raug pom.

Ua ntej sau cov tshuaj thiab tsis tu ncua nyob rau yav tom ntej, kev tshawb fawb ntawm hepatic kev ua haujlwm yuav tsum tau ua. Qhov ntau zaus ntawm kev saib xyuas cov haujlwm ntawm hepatic enzymes: thawj peb lub hlis - txhua 6 lub lis piam, tom qab ntawd thaum tseem tshuav ib xyoos - 1 zaug hauv ob hlis, yav tom ntej - 1 zaug hauv rau lub hlis. Kev tshuaj ntsuam uas ua haujlwm los txiav txim siab lub siab ua haujlwm yog ua haujlwm nrog nce ntxiv. Yog tias qhov koob tshuaj nce rau 80 mg ib hnub twg, kev tswj hwm yuav tsum tau ua ib zaug txhua peb lub hlis. Qhov cub tsis ua hauj lwm txuas ntxiv yog muaj qhov pheej ua ntxiv rau transaminase kev ua ub no (3 zaug hauv qhov sib piv nrog theem pib).

Thaum cev xeeb tub, kev tshem tawm lipid-txo cov tshuaj ntawm cov txiaj ntsig ntawm kev kho lub sijhawm ntev ntawm thawj hypercholesterolemia tsis muaj qhov cuam tshuam loj.

Cov poj niam ntawm lub hnub nyoog yug menyuam uas tsis siv tshuaj xeeb tsis pom zoo kom siv Ovenkor.

Nrog rau txo cov thyroid ua haujlwm (hypothyroidism) lossis nyob rau ntawm qhov muaj qee yam mob raum (nephrotic syndrome) nrog kev nce hauv cov roj (cholesterol), cov kab mob hauv qab yuav tsum tau kho ua ntej.

Txais tos ntawm Ovenkor tuaj yeem ua rau txoj kev txhim kho myopathy nrog qhov tshwm sim txuas ntxiv ntawm rhabdomyolysis thiab lub raum tsis ua haujlwm.

Thaum tsis muaj kev qhia tias mob, mob nqaij pob txha, mob leeg tsis muaj zog los yog mob nkees, koj yuav tsum sab laj nrog kws kho mob, tshwj xeeb yog tias cov kev cuam tshuam no nrog cov ua npaws lossis malaise. Kwv yees / ntsuas tshuaj myopathy, kev kho yog tsis ua hauj lwm.

Txhawm rau soj ntsuam qhov tshwm sim ntawm tus mob myopathy, nws raug nquahu kom ntsuas ntsuas KFK tus nqi. Hauv qhov txawv txav mob ntawm qhov mob tom qab sternum, noj cov tshuaj yuav tsum raug txiav txim siab.

Aries ua tau zoo rau hauv daim ntawv ntawm kev kho mob tshuaj thiab thaum sib xyaw nrog bile acid sequestrants.

Tus kws kho mob txiav txim siab lub sijhawm ntawm kev kho mob ib tus zuj zus.

Cev xeeb tub thiab lactation

Raws li cov lus qhia, Ovenkor yog contraindicated rau cov poj niam thaum cev xeeb tub / lactation.

Muaj tsawg cov pov thawj ntawm kev nthuav dav ntawm kev txawv txav ntawm cov menyuam tshiab uas lawv niam noj cov tshuaj. Cov poj niam ntawm lub hnub nyoog yug menyuam noj simvastatin yuav tsum siv txoj kev tiv thaiv. Thaum cev xeeb tub tshwm sim, Ovenkor raug muab tso tseg tam sim ntawd.

Yeeb tshuaj sib cuam tshuam

erythromycin, immunosuppressants, telithromycin, clarithromycin, cytostatics, cov tshuaj tua kab mob (ketoconazole, itraconazole), nefazodone, fibrates, nicotinic acid hauv kev txhaj tshuaj siab, HIV tiv thaiv kab mob tiv thaiv: muaj kev pheej hmoo ntawm myopathy,
danazol, cyclosporine, gemfibrozil thiab lwm cov fibrates (tsis suav nrog fenofibrate), niacin, amiodarone, verapamil, diltiazem: kev pheej hmoo ntawm myopathy / rhabdomyolysis,
qhov ncauj anticoagulants (fenprocoumone, warfarin): kev pheej hmoo los ntshav, soj ntsuam cov ntshav coagulability ua ntej kev kho mob thiab feem ntau txaus nyob rau hauv thawj zaug ntawm kev kho,
digoxin: nce rau hauv nws cov theem ntshav,
colestipol, colestyramine: txo qis kev noj qab haus huv (koj tuaj yeem noj Ovencor 4 teev tom qab noj cov tshuaj no, thaum txoj kev loj hlob ntawm cov txiaj ntsig tseem ntxiv tau sau tseg),,
txiv kab ntxwv qaub kua txiv (ntau tshaj li 1000 ml ib hnub): qhov nce ntxiv ntawm cov qib kev tiv thaiv tsis pub tawm tsam HMG-CoA reductase nyob rau hauv cov ntshav ntshav (kev sib xyaw ua ke yuav tsum zam).

Cov qauv ntawm Ovenkor yog: Simvalimite, Sinkard, Zorstat, Simvastatin, Holvasim, Simgal, Zokor, Simvor, Simlo, Vasilip, Simvastol.

Qhia txog ntawm cov tshuaj

Aries - Tus neeg sawv cev hypolipidemic los ntawm pab pawg statins, tus tiv thaiv HMG-CoA reductase. Nws yog cov khoom tsim tawm, vim tias nws tau kaw lub nplhaib lactone hauv nws cov qauv, uas yog hydrolyzed tom qab nkag mus rau hauv lub cev.

Cov qauv ntawm statin lactone nplhaib zoo ib yam li cov ntu ntawm HMG-CoA reductase enzyme. Raws li lub hauv paus ntsiab lus ntawm kev sib tw kev sib tua, ib qho statin qauv qauv khi rau qhov ntawd ntawm coenzyme A receptor qhov twg no enzyme txuas. Lwm feem ntawm statin lwg me me tiv thaiv kev hloov pauv ntawm hydroxymethylglutarate rau mevalonate, ib qho nruab nrab hauv cov hluavtaws sib xyaw ua ke ntawm cov roj (molecules) roj. Kev txwv tsis pub muaj kev ua haujlwm ntawm HMG-CoA reductase ua rau muaj cov kev hloov tshwm sim ntxiv, ua rau muaj qhov txo qis ntawm cov roj uas txhaws txaus thiab muaj kev cuam tshuam hauv kev ua haujlwm ntawm LDL receptors thiab, raws li, kev nrawm catabolism ntawm LDL cov roj (Xc).

Cov nyhuv hypolipidemic ntawm statins yog txuam nrog qhov kev txo qis ntawm tag nrho cov cholesterol vim LDL cov cholesterol. Qhov txo qis hauv LDL yog koob tshuaj-siv thiab tsis yog linear, tab sis exponential.

Statins tsis cuam tshuam rau kev ua haujlwm ntawm lipoprotein thiab hepatic lipases, tsis txhob cuam tshuam loj heev ntawm kev sib txuas thiab catabolism ntawm cov roj ntsha dawb, yog li ntawd, lawv cov txiaj ntsig ntawm theem TG yog theem nrab thiab tsis ncaj los ntawm lawv cov kev cuam tshuam tseem ceeb los txo qis LDL-C. Kev poob qis hauv theem ntawm TG thaum kho nrog statins pom meej cuam tshuam nrog kev qhia ntawm cov seem (apo E) receptors nyob rau saum npoo ntawm hepatocytes koom nrog catabolism ntawm STD, uas muaj li 30% TG.

Raws li kev tshawb fawb tswj tau, simvastatin nce qib ntawm HDL-C rau 14%.

Ntxiv rau qhov teebmeem lipid-txo qis, statins muaj cov txiaj ntsig zoo ntawm endothelial kawg (preclinical kos npe ntawm thaum ntxov atherosclerosis), nyob rau ntawm phab ntsa vascular, atheroma lub xeev, txhim kho rheological ntshav, muaj antioxidant, antiproliferative zog. Muaj cov pov thawj tias simvastatin txhim kho endothelial kev ua haujlwm tom qab 30 hnub ntawm kev kho.

Kev siv cov simvastatin tau txuas nrog qhov txo qis ntawm lub cev ntawm cov mob plawv, tsis hais txog qib pib ntawm LDL-C.

Sau cov analogues

Daim ntawv tso tawm (los ntawm qhov nrov)	Nqe, tshiav.
Aries
20 mg ntsiav tshuaj, 30 pcs.	476
Avestatin
Actalipid
Atherostat
Tab. 0,02 Zauv 30 (AVVA RUS OJSC / Sti - Med - Sorb OJSC (Russia)	232
Tb PO 0.02 No. 30 (ABVA RUS OJSC / Sti - Med - Sorb OJSC (Russia)	232
Vasilip
Tab 10mg N28 Vector (KRKA, dd. Qhov chaw tshiab / ntim. Vector (Russia)	329.60
Tab 20mg N28 Vector (KRKA, dd. Qhov chaw tshiab / ntim. Vector (Russia)	458.20
Tab 40mg N28 (KRKA - Rus LLC (Russia)	628.20
Vero-Simvastatin
Zovatin
Zokor
28mg No. 28 tab (Merck Sharp thiab Dome, UK. (Askiv)	176
Zokor Forte
40mg No. 14 tab (Merck Sharp thiab Dome, UK. (Askiv)	458
Tab 40mg N14 (Merck Sharp thiab Dome, UK. (Tebchaws Askiv)	519.90
Zorstat
SIMVAHEXAL
Tab 20mg N30 (Hexal AG (Lub Tebchaws Yelemees)	287.10
Tab 10mg N30 (Hexal AG (Lub Tebchaws Yelemees)	319.10
Tab 40mg N30 (Hexal AG (Lub Tebchaws Yelemees)	484.70
Simvakard
Tab 20mg N28 (ZENTIVA a.s. Czech koom pheej (Czech koom pheej)	172
Tab 10mg N28 (ZENTIVA a.s. Czech koom pheej (Czech koom pheej)	218.80
10mg No. 28 tab (Zentiva k.s. (Czech Republic)	242
Simvacol
Simvalimite
Simvastatin
10mg No. 30 tab p / pl. (Borisovsky ZMP OJSC (Belarus)	38.60
20mg No. 30 tab p / pl.o (Borisovsky ZMP OJSC (Belarus)	47.50
Tab 10mg N30 Alsi (Alsi Pharma ZAO (Russia)	53.70
Tab p / pl. Txog 20mg N30 Alsi (Alsi Pharma ZAO (Russia)	54.50
20mg No. 30 tab p / pl.o AVVA RUS (AVVA RUS OJSC (Russia)	68.30
10mg No. 30 tab p / pl.o (Ozone LLC (Russia)	89.10
20mg No. 30 tab p / pl.o (Ozone LLC (Russia)	113.80
Tab 20mg N30 (Verteks ZAO (Russia)	147.60
Tab 10mg N30 (Verteks ZAO (Russia)	207.30
Tab 20mg N20 (Hemofarm A.D. (Serbia))	257.30
Simvastatin alkaloid
10mg Tsis Muaj No. 28 tabp / pl. (Alkaloid AO (Macedonia)	59.80
Simvastatin Zentiva
10mg No. 28 tab (Zentiva k.s. (Czech Republic)	259.90
20mg No. 28 tab (Zentiva k.s. (Czech Republic)	335
40mg No. 28 tabp / pl. (Zentiva k.s. (Czech koom pheej)	498.70
Simvastatin Pfizer
Simvastatin Sanofi
Simvastatin * (simvastatin *)
Simvastatin-ALSI
Simvastatin-SZ
40 mg ntsiav tshuaj, 30 pcs. (Hnub Qub Qaum Teb, Russia)	91
Simvastatin-teva
Simvastatin-ferein
Simvastatin-Chaikafarma
Simvastatin granules
Simvastol
Tab 10mg N28 (Gideon Richter OJSC (Hungary)	197.10
Simvor
Tab po 40mg No. 30 (Ranbaxi Laboratories Limited (Is Nrias teb)	60.10
Tab po 20mg N30 (Ranbaxi Laboratories Limited (Is Nrias teb)	282
Ib Sim Neej
Tab 10mg N28 (Aivex Pharmaceuticals s.r.o. (Czech koom pheej)	287
40mg No. 84 tab (Teva Czech Enterprises s.r.r.o. (Czech Republic)	304.40
28mg No. 28 tab (Teva Czech Enterprises s.r.o. (Czech koom pheej)	321.50
20mg Tsis Yog. 28 daim ntawv p / pl. (Teva Czech qhauj s.r.r.o (Czech koom pheej)	410
10mg No. 84 tab p / pl. (Teva Czech qhauj s.r.r.o (Czech koom pheej)	609.90
40mg No. 28 thau p / pl. (Teva Czech qhauj s.r.r.o (Czech koom pheej)	678
20mg No. 84 tab (Teva Czech Enterprises s.r.o. (Czech Republic)	870
Tab 40mg N84 (Aivex Pharmaceuticals s.r.o. (Czech koom pheej)	1505
Simlo
Tab 10mg No. 28 (Ipka Laboratories Limited (Is Nrias teb)	202.90
Tab 20mg N28 (Ipka Laboratories Limited (Is Nrias teb)	293.60
Yooj Yim
Syncard
Holvasim

Ib tus qhua qhua tshaj tawm hnub tas sijhawm

Ntev npaum li cas Ovencor siv sijhawm los xav tias tus neeg mob txhim kho?
Cov neeg tuaj koom kev soj ntsuam feem ntau tom qab 1 hnub hnov qhov kev txhim kho. Tab sis qhov no yuav tsis raug rau lub sijhawm uas koj yuav txhim kho. Nrog koj tus kws kho mob xav ntev li cas koj yuav tsum tau noj cov tshuaj no. Cov lus hauv qab no qhia cov kev tshwm sim ntawm kev tshawb fawb txog kev pib ua haujlwm zoo.

Cov Tswv Cuab

1 hnub

Ib tus qhua qhua tau tshaj tawm txog kev teem caij

Lub sijhawm twg zoo dua los noj Ovenkor: ntawm lub plab khoob, ua ntej, tom qab lossis nrog zaub mov noj?
Cov neeg siv Website feem ntau qhia txog cov tshuaj no rau ntawm lub plab tas. Txawm li cas los xij, tus kws kho mob yuav qhia lwm lub sijhawm. Daim ntawv tshaj tawm qhia tias thaum tus neeg mob xam phaj tas cov tshuaj noj.

Cov Tswv Cuab

Ntawm ib plab khoob

Kaum xya qhua qhia txog cov neeg mob lub hnub nyoog

Cov Tswv Cuab	%
> 60 xyoo lawm	12

70.6%

46-60 xyoo

17.6%

30-45 xyoo

Cov lus qhia raug rau siv

(Simvastatin) Kev sau npe: LSR-002033/08
Lub npe Kev Lag Luam: Aries

Lub Npe Tsis Pub Hauv Lub Npe: Simvastatin * (simvastatin *)

Dosage daim ntawv: zaj duab xis-coated ntsiav tshuaj
Muaj pes tsawg leeg: 1 zaj duab xis-coated ntsiav tshuaj muaj
yam tshuaj: Ariescore - 10 mg lossis 20 mg,
tus zam: microcrystalline cellulose, lactose (mis nyuj qab zib), pregelatinized hmoov txhuv nplej siab (hmoov txhuv 1500), colloidal silicon dioxide (aerosil), ascorbic acid, butylhydroxyanisole, stearic acid, magnesium stearate, opadry II (polyvinyl cawv, dub polyglycol, iron gol talc, hlau zas hlau oxide daj, hlau zas hlau oxide liab, titanium dioxide).
Kev piav qhia: puag ncig biconvex ntsiav tshuaj, zaj duab xis-coated, los ntawm xim av mus rau lub teeb xim av nrog lub pinkish zas.
Cov tshuaj pab pawg kho mob: lipid-txo tus neeg sawv cev, HMG-CoA reductase inhibitor.
ATX Cov Cai: C10AA01

Cov khoom txaus nyiam

Yuav ua li cas xaiv txoj cai piv rau
Hauv khw muag tshuaj, tshuaj feem ntau muab faib ua cov lus ua kom sib piv thiab cov duab analogues. Cov txheej txheem ntawm cov lus txhais suav nrog ib los yog ntau qhov kev dhia tshuaj qub uas muaj kev kho lub cev. Los ntawm cov qauv piv txwv yog cov tshuaj uas muaj cov tshuaj sib txawv, tab sis npaj rau kev kho mob ntawm tib cov kab mob.

Qhov sib txawv ntawm cov kis thiab kab mob
Cov kab mob kis tau yog tshwm sim los ntawm cov kab mob, kab mob, hu ua fungi thiab protozoa. Cov chav kawm ntawm kab mob tshwm sim los ntawm cov kab mob thiab cov kab mob feem ntau zoo sib xws. Txawm li cas los xij, kom paub qhov txawv ntawm qhov ua rau tus mob txhais tau tias xaiv qhov kev kho mob uas yuav pab tau sai sai nrog qhov malaise thiab yuav tsis ua mob rau tus menyuam.

Kev ua xua yog qhov ua rau mob khaub thuas
Qee tus neeg tau paub txog qhov xwm txheej uas tus menyuam yaus nyob ntev thiab ntau lub sijhawm muaj tus mob khaub thuas. Cov niam txiv coj nws mus rau cov kws kho mob, ua cov kev xeem, siv tshuaj, thiab vim li ntawd, tus me nyuam twb sau npe nrog kws kho mob raws li feem ntau mob. Qhov tseeb uas ua rau mob ntsws ua pa heev tsis txheeb xyuas.

Txoj hlab zis: kho mob chlamydial urethritis
Chlamydial urethritis feem ntau pom muaj nyob ntawm txoj kev siv ntawm urologist. Nws tshwm sim los ntawm tus kab mob intracellular parasite Chlamidia trachomatis, uas muaj cov khoom ntawm ob hom kab mob thiab kab mob, uas feem ntau xav tau cov tshuaj tua kab mob ntev mus rau kev siv tshuaj tua kab mob. Nws muaj peev xwm ua rau tsis muaj qhov mob tshwj xeeb ntawm txoj hlab zis rau txiv neej thiab poj niam.

Ariescorp, kev qhia ua daim ntawv thov (qauv thiab ntau npaum li cas)

Ua ntej pib txoj kev kho mob nrog Ovencor, tus neeg mob tau muab cov txheej txheem hypocholesterol noj cov zaub movCov. Cov tshuaj yuav tsum tau noj ib hnub ib zaug nyob rau yav tsaus ntuj, ntxuav cia nrog dej. Nrog kev noj zaub mov, cov tshuaj yuav tsum tsis cuam tshuam nrog. Pom zoo siv tshuaj rau txhua hnub hypercholesterolemia thaj tsam li 10 txog 80 mg. Hauv qhov no, qhov pib txhaj tshuaj yog 10 mg. Kev pauv hloov tau raug coj ntawm kev ncua sijhawm ib hlis. Hauv feem coob ntawm cov neeg mob, cov kev kho mob zoo tshaj plaws tshwm sim thaum noj Ovenkor hauv cov tshuaj txhua hnub txog 20 mg.

Rau cov neeg mob nrog Ischemic mob plawv lossis nws qhov kev pheej hmoo siab ntawm kev tsim kho cov tshuaj ib hnub zoo yog 20-40 mg, thiab thawj qhov yog 20 mg rau ib hnub. Koob tshuaj hloov kho tsis raug ua rau cov neeg mob tom qab 60 xyoo thiab cov neeg mob uas tsis tshua mob lub raum lossis tsis mob lub cev. Nrog tib lub sijhawm tswj hwm ntawm Ovenkoroma thiab Hauverapamil lossis Amiodarone kev noj tshuaj txhua hnub ntawm Ovenkor yuav tsum tsis pub ntau tshaj 20 mg.

Kev Sau ua ke, daim foos tso tawm

Ariescor yog kev npaj monocomponent, uas yog, nws tsuas muaj ib qho kev ua ub no - simvastatinCov. Cov khoom siv ntxiv ua ib ntu pabcuam: muab cov huab hwm coj, txhim kho kev txhim kho ntawm cov ntsiav tshuaj, khi txhua yam tshuaj rau ib leeg. Hauv kev npaj no, cellulose, hmoov txhuv nplej siab, ascorbic thiab citric acids, magnesium stearate, titanium dioxide, mis nyuj qab zib (lactose), polyethylene glycol 4000, talc yog siv rau cov laj thawj no.

Ariescor yog cov ntsiav tshuaj uas muaj nyob hauv ob qhov tshuaj - 10 lossis 20 mg. Lawv yog cov puag ncig, matte, them nrog lub plhaub dawb.

Pharmacological kev txiav txim

Ovenkor ntsiav tshuaj tau txwv kom muab zais ua cov khoom tsim txom. Lub simvastatin molecule muaj daim ntawv ntawm lub nplhaib lactone. Xws li, nws tsis tuaj yeem cuam tshuam nrog cov roj ua ntej. Tab sis hauv lub siab, nws qiv nws tus kheej rau kev hloov tshuaj. Cov nquag ua haujlwm ntawm simvastatin tau zoo ib yam li enzyme HMG-CoA reductase, uas tsim nyog rau kev sib txuas ntawm cov roj (cholesterol). Vim tias qhov ua kom yuam kev no, nws coj nws qhov chaw hauv cov tshuaj lom neeg. Lwm feem ntawm cov lwg me me nyob rau hauv rooj plaub no cuam tshuam nrog kev tsim cov roj ua ntej. Vim tias qhov twg, qhov synthesis ntawm nws cov lwg me me yuav raug txo kom tsawg.
Lub cev teb rau qhov kev poob hauv cov roj (cholesterol) los ntawm kev ua haujlwm ntawm LDL cov txais, nrawm rau lawv cov kev rhuav tshem. LDL yog cov rog "phem" uas pab txhawb kev tsim cov nyiaj tso rau ntawm cov hlab ntshav. Yog li, kev noj Ovenkor txo txoj kev pheej hmoo ntawm kev tsim mob atherosclerosis.

Zoo ib yam li cov statins, Ovenkor tsis cuam tshuam rau kev ua haujlwm ntawm cov enzymes uas zom cov rog (lipases), synthesis, thiab tawg ntawm cov roj dawb. Yog li, qhov kev txo qis ntawm cov rog nruab nrab (triglycerides, TG) feem ntau yuav yog los ntawm kev ua kom muaj cov qe ntshav siab. Lawv txhawb nqa qhov ua kom tsis haum ntawm lipoproteins ntau ntom nruab nrab, 30% muaj TG.

Nws yog pov thawj tias kev siv tshuaj yeeb tshuaj Ariescor:

zoo cuam tshuam rau lub xeev ntawm txheej sab hauv ntawm cov hlab ntsha (endothelium), cov phab ntsa ntawm cov hlab ntsha,
normalizes ntshav txaus
muaj cov antioxidant zog
txo qhov tshwm sim ntawm cov mob plawv.

Raws li cov lus qhia rau kev siv nrog Ovenkor, ib qho kev txhim kho ntawm lub xeev ntawm endothelium tau sau tseg tom qab ib hlis ntawm kev kho.

Cov tshuaj yog tus cwj pwm los ntawm kev nqus zoo. Qhov siab tshaj plaws hauv cov ntshav tshwm sim 4 teev tom qab kev noj cov ntsiav tshuaj Ovenkor hauv lub cev. Thawj qhov kev hloov pauv hauv cov qib roj cholesterol siab tau pom tom qab 2 lub lis piam.

Feem ntau ntawm simvastatin nrog cov kua tsib nkag mus rau txoj hnyuv, los ntawm qhov uas nws tau zom nrog quav. Daim ntawv tsis ua haujlwm hauv cov tshuaj yog tawm los ntawm lub raum.

Txoj kev ntawm daim ntawv thov, ntau npaum li cas

Kev kho mob nrog Ovencor yuav tsum noj zaub mov ua ntej pib noj tshuaj, zoo li thoob plaws thaum kawg ntawm kev kho.

Cov koob tshuaj ntawm cov tshuaj raug xaiv xaiv tus kheej. Nws raug nquahu kom pib siv cov tshuaj me me, nrog nws nce ntxiv. Peb tau sau saum toj no tias qhov yuav txo tau ntau hauv cov cholesterol yog ua tiav 28 hnub tom qab pib siv tshuaj. Vim li no qhov muab tshuaj kho ntau dua tsis qhia qhov tseeb.

Qhov pom zoo thawj zaug ntawm Ovenkor yog 5-20 mg / hnub, thiab qhov ntau tshaj yog 40 mg / hnub. Rau cov neeg mob noj tshuaj tiv thaiv kab mob, kev siv simvastatin tau txwv rau ib koob ntawm 5 mg / hnub. Hauv kev mob raum tsis ua haujlwm, kev qhia tswv yim pib nrog koob tshuaj 5-10 mg / hnub.

Qhov ntau ntxiv thiab lub cev txav tau ntawm cov tshuaj rau lub cev tsis cuam tshuam nrog zaub mov. Koj tuaj yeem nqa nws ua ntej / tom qab / thaum noj mov, tsis txhob hnov qab haus dej ntau. Qhov tseem ceeb tshaj plaws yuav tsum tau ua: ntsiav tshuaj yuav tsum haus ib zaug ib hnub nyob rau yav tsaus ntuj.

Kev sib txuam

Nrog rau kev coj ua ib txhij ntawm warfarin thiab qee yam tshuaj anticoagulants nrog Avencor, cov nyhuv ntawm cov tom kawg tau ua kom zoo dua. Nws kuj potentiates lub tshuaj lom cawv mus rau lub siab, tshuaj uas cuam tshuam rau qhov khoom nruab nrog.

Vim tias qhov txaus ntshai ntawm rhabdomyolysis, kev siv ntawm cov tshuaj tsis tso cai:

ua ke nrog keto, itraconazole, muaj koob tshuaj vitamin PP,
cov neeg mus txhaj tshuaj tiv thaiv kab mob.

Cov kws kho mob sau tseg ib kis ntawm qhov pib ntawm rhabdomyolysis tom qab ib koob tshuaj simvastatin nrog sildenafil. Cov tshuaj no yog siv los kho erectile kawg.

Tus nqi Ovenkor yog cuam tshuam loj heev ntawm qhov kis ntawm kev muag khoom. Hauv ntau lub nroog thiab cov khw muag tshuaj ntawm Lavxias, nws txawv heev. Yog li ib pob ntawm 10 mg tuaj yeem them los ntawm 275 rubles, thiab 20 mg muab tshuaj - los ntawm 419 txog 578 rubles.

Hauv txhua lub tsev muag tshuaj koj tuaj yeem nrhiav cov analogues ntawm Ovenkor - cov tshuaj nrog tib cov tshuaj nquag, tab sis los ntawm cov chaw tsim tshuaj sib txawv. Simvastatin yog ib feem ntawm: Simvagesal, Zokor, Simvor, Simvakard, Simvastatin, Simvastol, Simgal, Simlo, Vasilip. Ib qho ntxiv rau tus nqi, cov tshuaj no sib txawv hauv cov tshuaj noj kom pheej yig. Piv txwv, muaj cov tshuaj nrog 5 thiab 40 mg ntawm cov tshuaj nquag. Qhov no yooj yim yog tias tus kws kho mob tau sau cia li ib koob tshuaj.

Cov ntaub ntawv npaj los ntawm tus sau phau ntawv ntawm qhov project
raws li txoj cai kho ntaub ntawv ntawm lub xaib.

Pheej Yig pauv hloov rau Ovenkor

Cov analogue yog pheej yig dua los ntawm 313 rubles.

Simvastatin yog qhov muaj txiaj ntsig ntau yam tshuaj Lavxias nrog rau kev ua haujlwm zoo tib yam hauv cov tshuaj muaj pes tsawg leeg, tab sis ntawm koob tshuaj tsawg kawg 10 mg rau ib ntsiav tshuaj. Nws yog tshuaj rau kev kho mob ntawm thawj hypercholesterolemia thiab theem siab hyperlipidemia. Ua tiav cov npe ntawm cov cim tuaj yeem nrhiav tau hauv cov lus qhia.

Simvastol (ntsiav tshuaj) Ntsuas: 4 Sab saum toj

Cov analogue yog pheej yig dua los ntawm 265 rubles.

Cov analogue yog pheej yig dua los ntawm 173 rubles.

Lwm qhov hloov pauv txawv tebchaws rau Ovenkor, uas tseem hloov mus ua qhov zoo tshaj qhov "qub", txawm tias nws tsis txawv ntawm nws. Contraindicated nyob rau hauv cev xeeb tub, lactation thiab nyob rau hauv thaum yau. Tag nrho cov npe ntawm contraindications tuaj yeem nrhiav hauv cov lus qhia.