Cov Insulin Nruab Nrab - Npe Tshuaj

Hauv Lavxias Lavxias, kwv yees li 45 feem pua ​​ntawm cov neeg kuaj mob ntshav qab zib siv cov tshuaj insulin rau hauv lawv lub neej. Ua raws li cov txheej txheem kho, tus kws kho mob yuav muab tshuaj insulin rau luv, nruab nrab thiab ntev ntev.

Cov tshuaj tseem ceeb hauv kev kho mob ntshav qab zib yog insulins nruab nrab. Xws li cov tshuaj hormone siv tshuaj ib zaug lossis ob zaug ib hnub.

Txij li qhov nqus ntawm cov tshuaj tshwm sim ntau qeeb, cov suab thaj txo qis siv pib tsuas yog ib thiab ib nrab xuaj moos tom qab txhaj tshuaj.

Hom mob insulin

1. Kev siv tshuaj insulin sai sai pib txo qis ntshav qab zib kom 15-30 feeb tom qab nws txhaj rau hauv lub cev. Qhov siab tshaj plaws nyob rau hauv cov ntshav tuaj yeem ua tiav tom qab ib thiab ib nrab rau ob teev, ntawm qhov nruab nrab, xws li cov kua dej muaj peev xwm ua tau los ntawm 5 txog 8 teev.
2. Ib nrab-lub sij hawm insulin txo qis ntshav qabzib hauv cov qib ib thiab ib nrab rau ob teev tom qab nws tswj hwm. Qhov siab tshaj plaws ntawm cov tshuaj nyob hauv cov ntshav tau pom tom qab 5-8 teev, cov nyhuv ntawm cov tshuaj nyob rau 10-12 teev.
3. Cov tshuaj insulin ntev ua ntev li ob mus rau plaub teev tom qab kev tswj xyuas lub cev. Qhov siab tshaj plaws ntawm kev xav ntawm cov khoom hauv cov ntshav tau pom tom qab 8-12 teev. Tsis zoo li lwm hom tshuaj insulin, cov tshuaj no siv tau rau ib hnub. Tseem muaj cov insulins uas muaj cov nyhuv hypoglycemic rau 36 teev.

Tsis tas li, insulin, nyob ntawm txoj kev ntawm kev ua kom huv, tuaj yeem yog qhov dog dig, monopic thiab monocomponent. Hauv cov txheej txheem li niaj zaus, kev ua kom huv yog ua tiav siv chromatography, monopic ncov insulin yog tau los ntawm kev ua kom huv los ntawm gel chromatography. Rau monocomponent insulin, ion-txauv cov chromatography siv thaum ua kev huv.

Cov neeg kawm ntawv ntawm kev ua kom huv yog txiav txim los ntawm tus naj npawb ntawm proinsulin hais ib lab hais txog insulin. Lub sijhawm ntev ua haujlwm ntawm cov tshuaj insulin tuaj yeem ua tiav vim qhov tseeb tias cov tshuaj hormones yog raug kho tshwj xeeb thiab cov protein thiab zinc ntxiv rau nws.

Tsis tas li ntawd, cov tshuaj insulins tau muab faib ua ntau pawg, nyob ntawm tus qauv ntawm lawv cov kev npaj. Hom tshuaj tua cov txiv neej insulin yog tau los ntawm cov kab mob ua ke thiab semisynthesis los ntawm npua npua. Heterologous insulin yog synthesized los ntawm kev mob siab ntawm nyuj thiab npua.

Ib nrab hluavtaws tib neeg cov kua dej tau los ntawm kev hloov cov amino acid alanine nrog threonine. Xws li cov tshuaj insulin feem ntau siv yog tias cov mob ntshav qab zib muaj cov tshuaj tiv thaiv insulin, kev fab tshuaj rau lwm cov tshuaj.

Nruab Nrab Sijhawm Insulin

Qhov siab tshaj plaws yuav pom tau tom qab 6-10 teev. Lub sijhawm ua haujlwm ntawm cov tshuaj yog nyob ntawm ntau npaum li cas xaiv.

Hauv qhov tshwj xeeb, nrog kev qhia ntawm 8-12 units ntawm cov tshuaj hormones, insulin yuav ua haujlwm rau 12-14 teev, yog tias koj siv ntau npaum ntawm 20-25 units, cov tshuaj yuav ua 16-18 teev.

Ib qho tseem ceeb ntxiv yog qhov ua tau ntawm kev sib xyaw nrog cov tshuaj insulin ceev. Nyob ntawm cov tsim khoom thiab muaj pes tsawg leeg, cov tshuaj muaj npe sib txawv. Cov paub zoo tshaj plaws yog insulins ntawm lub sijhawm nruab nrab:

• Insuman Bazal,
• Biosulin N,
• Berlinsulin-N basal,
• Homofan 100,
• Protofan NM,
• Humulin NRH.

Tsis tas li ntawd nyob rau hauv txee ntawm cov chaw muag tshuaj, niaj hnub siv yeeb tshuaj ntawm Lavxias teb sab ntau lawm Brinsulmi-di ChSP tau muaj, uas muaj cov ncua ntawm insulin thiab tshuaj tiv thaiv.

Insulins ncua sijhawm ntev yog qhia rau:

1. Yam 1 ntshav qab zib mellitus,
2. Yam 2 Ntshav Qab Zib mellitus,
3. Yog tias muaj teeb meem rau cov ntshav qab zib ua rau ketoacidosis, acidosis,
4. Nrog rau kev txhim kho ntawm cov mob hnyav, kis kab mob sib kis, kev phais mob ntev, tom qab lub sijhawm ntev, kev mob tshwm sim, kev ntxhov siab hauv cov neeg mob ntshav qab zib.

Daim ntawv thov lawm

Qhov txhaj tshuaj yog ua tiav hauv plab, ncej puab. Lub xub pwg, pob tw. Qhov ntau npaum li cas tau txiav txim siab ntawm tus kheej, ntawm kev pom zoo ntawm tus kws kho mob tuaj koom. Kev tswj hwm qhov quav ntawm cov tshuaj yog txwv tsis pub.

Nws yog ib qho tseem ceeb kom ua raws txhua tus kws kho mob cov lus pom zoo rau xaiv hom tshuaj, tshuaj noj thiab sijhawm kis. Yog hais tias tus mob ntshav qab zib tau txav los ntawm nqaij npuas los yog nqaij nyug insulin rau tib neeg zoo sib xws, yuav tsum tau txhaj tshuaj.

Ua ntej tswj hwm tshuaj, lub vial yuav tsum tau maj mam shaken kom cov kuab tshuaj tau zoo kiag li thiab ib cov kua turbid ua kua. Qhov xav tau qhov ntau ntawm cov tshuaj insulin yog tam sim ntawd kos rau hauv cov phwj thiab txhaj tshuaj.

Koj tsis tuaj yeem ua lub zog co co ntawm lub raj mis kom cov npuas dej tsis tuaj yeem, qhov no yuav cuam tshuam nrog xaiv cov tshuaj kom raug. Lub koob tshuaj insulin yuav tsum sib haum nrog cov tshuaj hormone siv.

Ua ntej kev qhia ntawm insulin, qhov chaw txhaj tshuaj tsis tas yuav tsum ua kom tawm. Nws yog ib qho tseem ceeb ntawm lwm qhov chaw txhaj tshuaj. Saib xyuas yuav tsum tau ua tib zoo xyuas kom meej tias rab koob tsis nkag rau cov hlab ntshav.

1. Kev coj ntawm insulin hauv ntshav qab zib mellitus yog tau ua tiav 45-60 feeb ua ntej noj mov 1-2 zaug hauv ib hnub.
2. Cov neeg laus rau cov neeg uas muab tshuaj rau thawj zaug yuav tsum tau txais thawj zaug ntawm 8-24 units ib hnub ib zaug.
3. Nyob rau hauv qhov muaj qhov siab rhiab heev rau lub cev, cov menyuam yaus thiab cov neeg laus raug tswj tsis pub ntau tshaj 8 chav nyob rau ib hnub.
4. Yog tias rhiab heev rau cov tshuaj hormones raug txo, nws raug tso cai siv ntau tshaj 24 units ib hnub.
5. Qhov ntau npaum li cas ib cov tshuaj tuaj yeem yog 40 units. Tshaj li cov kev txwv no tsuas yog ua tau rau hauv rooj plaub tshwj xeeb nkaus xwb.

Ib nrab-lub sij hawm tshuaj insulin tuaj yeem siv ua ke nrog insulin luv luv. Hauv qhov no, insulin ceev yog sau ua ntej daim ntaub qhwv. Qhov kev txhaj tshuaj yog ua tiav tam sim ntawd tom qab cov tshuaj sib tov.

Hauv qhov no, nws yog ib qho tsim nyog yuav tau soj ntsuam cov tshuaj muaj zog ntawm cov kua dej, vim nws yog txwv tsis pub tov zinc npaj nrog phosphate-uas muaj cov tshuaj hormones.

Ua ntej thov cov tshuaj, lub vial yuav tsum tau ua tib zoo kuaj. Yog tias plaub ya ri los yog lwm qhov tshwm sim hauv nws nrog kev nplawm, insulin tsis pub. Cov tshuaj yog muab raws li cov lus qhia txuas nrog tus cwj mem syringe. Txhawm rau zam kom tsis txhob ua txhaum, tus kws kho mob yuav tsum qhia koj kom siv cov cuab yeej nkag mus rau hauv qhov tshuaj hormones.

Cov poj niam muaj mob ntshav qab zib thaum lub caij xeeb tub yuav tsum saib xyuas lawv cov ntshav qab zib. Hauv txhua peb lub hlis ntawm kev xeeb tub, nws yog ib qho tsim nyog yuav tau kho cov tshuaj ntau npaum li cas, nyob ntawm qhov xav tau ntawm lub cev.

Tsis tas li, kev hloov pauv ntawm koob tshuaj yuav tsum muaj thaum lub sijhawm pub niam mis.

Kev faib tawm ntawm cov tshuaj insulin

Cov tshuaj insulin yog ib qho tseem ceeb uas tsim los ntawm pawg ntawm pancreatic hlwb nyob hauv nws tus Tsov tus tw.

Lub luag haujlwm tseem ceeb ntawm cov tshuaj nquag yog tswj cov txheej txheem metabolic los ntawm kev ntsuas lub cev cov ntshav qabzib hauv cov ntshav. Kev tsis hnov ​​qab cov tshuaj muaj zog, uas ua rau cov piam thaj nce siab, yog hu ua ntshav qab zib.

Cov neeg muaj tus mob no yuav tsum tau muaj kev pab txhawb kho thiab kho kev noj haus kom zoo.

Txij li qib qib hauv lub cev hauv lub cev tsis txaus los kho lub luag haujlwm, cov kws kho mob tau muab tshuaj rau cov tshuaj hloov, cov tshuaj ua kom muaj zog uas yog cov tshuaj insulin tau los ntawm kev sim tshuaj. Hauv qab no yog hom insulin tseem ceeb, ntxiv rau qhov kev xaiv ntawm hom tshuaj no lossis yam tshuaj twg.

Pawg lawm

Muaj ntau yam kev faib tawm ntawm lub hauv paus ntawm qhov twg tus kws endocrinologist xaiv ib txoj kev kho mob. Los ntawm keeb kwm thiab hom, cov tshuaj hauv qab no tau cais:

• Cov tshuaj insulin los ntawm cov txiav mob ntawm cov neeg sawv cev ntawm cov nyuj. Nws qhov sib txawv ntawm cov tshuaj hormones ntawm tib neeg lub cev yog qhov nyob ntawm peb lwm cov amino acids, uas nkag mus rau kev txhim kho cov kev tsis haum tshuaj.
• Cov tshuaj tua kab ntsig Porcine yog ze dua hauv cov qauv tshuaj rau tib neeg lub cev. Nws qhov sib txawv yog hloov ntawm tsuas yog ib qho amino acid nyob hauv cov protein protein.
• Tus whale npaj txawv ntawm theem pib tib neeg cov tshuaj hormones txawm ntau dua li cov sib txuas los ntawm nyuj. Nws siv tsis tshua muaj neeg siv.
• Tib neeg cov tshuaj sib xyaws, uas yog sib txuas ua ob txoj hauv kev: siv Escherichia coli (tib neeg insulin) thiab los hloov cov "amino acids" tsis haum rau cov kab mob porcine hormone (hom tshuaj tiv thaiv txhob kaw).

Cov tshuaj insulin molecule - qhov me me hauv qhov loj tshaj plaws ntawm lub cev, muaj 16 amino acids

Txheej Txheem

Cov kev cais hauv qab no ntawm hom insulin raws li tus naj npawb ntawm. Yog hais tias cov tshuaj muaj kev ua ke ntawm cov txiav ntawm ib qho tsiaj ntawm ib tus tsiaj, piv txwv li, tsuas yog npua lossis tsuas yog tus heev nyuj, nws yog hais txog cov neeg sawv cev monovoid. Nrog kev sib txuam ua ke ntawm kev rho tawm ntawm ntau hom tsiaj, insulin yog hu ua kev sib xyaw.

Contraindications thiab kev noj ntau dhau

Nrog rau kev muab tshuaj tsis yog, tus neeg mob yuav muaj cov tsos mob ntawm lub qog ua kom ntshav tawm hws, ua kom tsis muaj zog, ua paug ntawm daim tawv nqaij, lub plawv nchav, tshee tshee, poob siab, xeev siab, tingling nyob rau ntau qhov chaw ntawm lub cev, mob taub hau. Tus neeg kuj tseem tuaj yeem ua lub cev ua ntej thiab ua pa tsis xeev.

Yog tias kuaj pom ntshav qog ntshav me lossis nruab nrab, tus neeg mob yuav tsum tau txais cov koob tshuaj nyob rau thaj chaw ntawm cov ntsiav tshuaj, kua txiv, zib ntab, qab zib thiab lwm yam khoom uas muaj suab thaj.

Yog tias kuaj pom tus mob ntshav qab zib tsawg kawg, tus neeg tsis nco qab lawm los yog tsis nco qab lawm, 50 ml ntawm 50% kua qabzib tau txhaj nrawm rau tus neeg mob. Tom ntej no yog qhov txuas ntxiv txuas ntxiv ntawm 5% lossis 10% aqueous kua nplaum. Tib lub sijhawm, lawv saib xyuas cov ntsuas ntawm qab zib, creatinine, thiab urea hauv cov ntshav.

Thaum tus mob ntshav qab zib rov qab nco qab, nws tau muab zaub mov nplua nuj hauv cov khoom noj carbohydrate kom qhov mob ntawm hypoglycemia tsis rov mob ntxiv.

Nruab nrab-lub sij hawm insulin yog contraindicated nyob rau hauv:

• ntshav qab zib,
• insuloma
• hypersensitivity rau lub cev hormone insulin lossis rau ib qho twg ntawm cov tshuaj.

Nws yog ib qho tseem ceeb uas yuav tau txiav txim siab tias cov tshuaj tuaj yeem ua rau muaj kev phiv uas feem ntau tshwm sim nrog kev noj ntau dhau, tshem tawm lossis noj zaub mov tsis zoo, ua haujlwm lub cev hnyav, thiab kev txhim kho ntawm tus kab mob kis loj. Hauv qhov xwm txheej no, cov tsos mob tau nrog ua ke nrog hypoglycemia, lub paj hlwb tsis meej, tshee tshee, pw tsis tsaug zog.

Qhov kev tawm tsam tsis haum yog feem ntau pom yog tias tus neeg mob tau muaj kev nkag siab ntau ntxiv rau insulin ntawm tsiaj keeb kwm. Tus neeg mob muaj kev ua pa luv, anaphylactic ceeb, tawm pob xoo ntawm daim tawv nqaij, ua xoo voos, ua pa nyuaj. Cov mob uas tsis haum heev tuaj yeem tsim kev puas tsuaj rau ib tus neeg lub neej.

Yog tias cov tshuaj siv tau ntev, kab mob lipodystrophy yuav raug pom ntawm qhov chaw txhaj tshuaj ntawm cov tshuaj insulin.

Nrog rau lub qog ntshav qab zib, qhov kev kub siab ntawm kev saib xyuas feem ntau cuam tshuam thiab qhov ceev ntawm qhov kev tawm tsam psychomotor poob qis, yog li thaum lub sijhawm rov qab los koj yuav tsum tsis txhob tsav lub tsheb lossis tsav cov kev ua txhaum loj.

Kev cuam tshuam nrog lwm yam tshuaj

Kev ncua, uas suav nrog zinc, yuav tsum tsis txhob nrog phosphate muaj cov tshuaj insulin, suav nrog lawv tsis xyaw nrog lwm cov tshuaj zinc-insulin.

Thaum siv cov tshuaj ntxiv, nws yog qhov yuav tsum tau sab laj nrog koj tus kws kho mob, vim tias ntau yam tshuaj yuav cuam tshuam rau cov piam thaj hauv kev ua haujlwm.

Txhim kho cov tshuaj hypoglycemic ntawm lub cev hormone insulin thiab nce qhov kev pheej hmoo ntawm hypoglycemia cov tshuaj xws li:

1. tetracyclines
2. monoamine oxidase inhibitors
3. cov tshuaj hypoglycemic qhov ncauj,
4. ifosfamides, alpha-blockers,
5. sulfonamides,
6. angiotensin hloov mus rau enzyme inhibitors,
7. tritoxylin,
8. disopyramids
9. fibrates
10. clofibrate
11. fluoxetines.

Kuj, pentoxifyllines, propoxyphenes, salicylates, amphetamines, anabolic steroids, thiab triphosphamides ua rau muaj cov nyhuv zoo sib xws.

Ua kom muaj zog lossis ua kom cov ntshav hauv lub ntsej muag muaj zog ntawm lub cev hormone salicylates, ntsev ntsev, beta-blockers, reserpine, clonidine. Ib yam li ntawd cuam tshuam rau lub cev thiab dej cawv.

Diuretics, glucocorticosteroids, sympathomimetics, tshuaj tiv thaiv qhov ncauj, tricyclic cov tshuaj tiv thaiv kab mob tuaj yeem ua kom qaug zog ntawm kev ua haujlwm ntawm insulin.

Hauv qhov yeeb yaj kiab hauv tsab xov xwm no, cov ntaub ntawv hais txog Protafan insulin yog qhia meej.

Tshuaj insulin yog dab tsi

Qhov tshuaj hormones no raug faib raws ntau yam ntxwv.

Nyob ntawm cov hauv paus chiv keeb, nws tshwm sim:

• Nqaij npuas. Nws yog qhov ze rau tib neeg.
• Nyuj. Nws tau txais los ntawm txoj cai pancreas. Feem ntau ua rau ua xua nyob rau hauv cov neeg mob, vim nws yog qhov txawv ntawm tib neeg.
• Tib neeg Nws yog synthesized siv Escherichia coli.
• Nqaij npuas hloov kho. Nws hloov tawm thaum hloov hauv npua tawm ib qho tsis haum amino acid rau ib tus neeg.

Hom insulin kuj sib txawv ntawm kev ua kom huv. Cov tshuaj ib txwm muaj yog cov tshuaj hormones hauv lub xeev ua kua, uas yauv ua rau pom thiab muaj qhov txhaws. Monopik kev npaj siab dhau los kho kev kho mob ib yam li ib txwm, txawm li cas los xij, ntxiv rau gel pom yog nqa tawm ntawm qhov kawg. Qhov no tso cai rau koj los ua nws me ntsis kom zoo nkauj. Cov tshuaj kho monocomponent yog qhov kev xaiv zoo tshaj plaws rau ib tus neeg. Qhov tsim nyog kev ua kom huv yog tau los ntawm kev pom thiab sieving ntawm qib molecular.

Hom insulin ntau yam nrawm nrawm. Lub sijhawm cov nyhuv xav tau tiav, lub sijhawm luv luv nws yuav yog.

Yog li ntawd, cov ntsiab cai cais:

• ultra luv
• luv
• nruab nrab sijhawm
• ntev ua yeeb yam.

Thawj ob qho lus tshaj tawm ua ntej txhua pluas noj kom tsis txhob nce cov piam thaj hauv cov ntshav ntxiv. Ob qho hauv qab no yog cov kev kho mob tseem ceeb thiab muab rau tus neeg mob txog ob zaug ib hnub.

Cov yam ntxwv ntawm insulin nruab nrab-ntev

Lub ntsiab tseem ceeb ntawm cov tshuaj nruab nrab nruab nrab yog tias nws ua 10 feeb tom qab noj. Qhov no yuav tsum tau coj mus rau hauv tus account.

Qee cov tshuaj muaj kev sib xyaw ua ke nrog cov tshuaj hormones luv thiab ultrashort yog tias cov nyhuv xav tau tam sim ntawd. Lub caij nyoog ntev ntawm kev ua haujlwm nruab nrab ntawm lub insulin yog txiav txim siab los ntawm nws cov kev ua kom tawg zuj zus. Nws tsis tsuas yog ua kom cov ntshav qabzib ntau, tab sis kuj tseem ua kom lub cev metabolism nce nrawm.

Kev siv insulin nruab nrab-ntev li cas

Ib qho yeeb tshuaj twg muaj daim ntawv thov nta. Cov tshuaj hormones yog tsis muaj.

Kev tsim kho hauv ntshav qab zib - tsuas yog haus txhua txhua hnub.

Cov cai rau siv cov tshuaj insulin ntawm lub sijhawm nruab nrab:

1. Thawj qhov uas cov ntshav qab zib yuav tsum tau ua ua ntej txhaj yog kom ntxuav thiab ntxuav nws txhais tes thiab ntawm qhov chaw txhaj tshuaj. Nws yuav tsum nco ntsoov tias cov tshuaj insulin rhuav tshem los ntawm kev haus cawv, yog li kev txhaj tshuaj muaj peev xwm ua tau tsuas yog tom qab kho thaj chaw ntawm daim tawv nqaij tau qhuav lawm.
2. Lub ampoule nrog cov tshuaj hormones yuav tsum tau ua kom huv si ua ntej siv. Thaum cov kua los ua homogeneous, nws tau npaj rau kev siv.
3. Cov muaj pes tsawg leeg tam sim ntawd ntaus mus rau hauv cov phwj. Nws raug nquahu kom siv cov insulin tshwj xeeb lossis cov xaum xaum. Lub sij hawm ib nrab-insulin yog siv tshwj xeeb rau kev txhaj tshuaj, txwv tsis pub nws tsis ua haujlwm.
4. Cov tshuaj yog txhaj rau hauv tus ncej puab, plab, pob tw los sis xub pwg. Qhov chaw txhaj tshuaj tshiab yuav tsum tau muab tshem tawm txij li yam tsawg kawg 2 centimeters.

Kev siv cov tshuaj kom raug yog qhov tseem ceeb ntawm nws cov txiaj ntsig.

Cov tshuaj insulin

Cov tshuaj hormones ntawm nruab nrab ntev yuav tsum muab cia ntawm chav sov, zam qhov nruab hnub ncaj qha. Qhov no yog qhov tsim nyog kom flakes thiab granules tsis ua rau hauv cov kua, hauv qhov xwm txheej zoo li no yuav nyuaj rau kev ua tiav.

Cov tshuaj insulin hauv nruab nrab yog siv, raws li txoj cai, txog li ob zaug hauv ib hnub. Tom qab qhia txog ntawm thawj koob tshuaj, koj yuav tsum ua tib zoo saib xyuas koj li kev noj qab haus huv.Yog tias siv tshuaj yaj yeeb ntev dua 4 teev, tom qab ntawd feem ntau yuav tsis tuaj yeem txhaj tshuaj ntxiv zaum ob.

Cov tshuaj insulin yog cov ib txwm thiab ua ke. Nrog kev kho mob ib txwm, tus neeg mob tau sau ib hom tshuaj uas sib xyaw cov tshuaj hormones ntawm ob qho tib si nruab nrab thiab lub sijhawm luv. Qhov ntxiv yog tias tus neeg mob yuav tsum tau ua rau cov neeg txhav tsawg dua, txawm li cas los xij, hom kev kho no tsis muaj txiaj ntsig. Cov kev kho mob zoo li no yog kho rau cov neeg laus, cov neeg mob uas muaj kev puas siab puas ntsws uas tsis tuaj yeem ntsuas nws tus kheej qhov koob tshuaj ntawm luv luv insulin.

Lub ntsiab ua ke tshuaj:

Hauv kev sib xyaw ua ke, cov tshuaj hormones luv thiab nruab nrab yog tswj hwm ntawm nws tus kheej. Cov txheej txheem no yog qhov zoo dua, raws li nws yoog mus rau lub txiav. Nws yog tshuaj rau yuav luag txhua tus neeg mob ntshav qab zib.

Cov Npe Tshuaj

Qhov siab tshaj plaws kho tau ntawm cov tshuaj insulin ntawm ib nrab sijhawm ua tiav 6-9 teev tom qab noj. Lub sijhawm ua li cas yog nyob ntawm seb qhov ntau npaum li cas xaiv.

Cov insulins uas nquag siv nruab nrab yog:

"Humulin NPH" muaj rau kev ncua rau kev tswj hwm hauv qab daim tawv nqaij. Cov tshuaj nquag ua haujlwm yog tib neeg insulin tsim los ntawm kev tshuaj ntsuam genetic engineering hom. Ua ntej siv, ampoule nrog cov tshuaj yuav tsum tau dov ob peb zaug ntawm lub xib teg. Qhov no yog qhov tsim nyog kom lub emulsion ua homogeneous, thiab qhov nag lossis daus tau sib xyaw nrog cov kua. Npaj kom siv cov khoom hauv tsos thiab xim zoo li mis nyuj. Xws li ib yam tshuaj twg, kev fab tshuaj tsis haum thiab phiv yog muaj.

Peb muab cov luv nqi rau cov nyeem ntawm peb lub xaib!

Yog tias koj muaj qhov ua xua, koj yuav tsum sab laj nrog kws kho mob sai. Tej zaum koj yuav tau hloov tshuaj lossis hom tshuaj insulin. Ntawm cov kev phiv tshuaj tiv thaiv, hypoglycemia tshwm sim ntau dua li lwm tus. Daim foos me me uas tsis muaj suab thaj tsis xav tau kev kho thiab kev kho mob. Yog tias cov tsos mob ntawm tus mob ntshav qab zib siab tshwm sim, koj yuav tsum nrhiav kev pab kho mob maj nrawm.

"Homofan 100" yog tsim tawm los ua qhov kev ncua rau kev coj ua subcutaneous. Cov tshuaj phiv yog semisynthetic tib neeg cov kua dej. Cov tshuaj raug txhaj rau li 2 zaug hauv ib hnub. Thawj txoj kev txhaj tshuaj yuav tsum yog ua rau thaum sawv ntxov 30-40 feeb ua ntej noj tshais. Qhov chaw txhaj tshuaj yuav tsum tau hloov pauv. Qhov siab tshaj plaws tau tiav ib teev tom qab kev txhaj tshuaj. Lub sijhawm tiv thaiv kev kho kom haum yog los ntawm 10 teev rau ib hnub. Nws nyob ntawm xaiv koob tshuaj.

Ntawm cov kev mob tshwm sim, cov feem ntau muaj xws li: urticaria, tawv nqaij khaus, mob ntawm qhov chaw txhaj tshuaj, tsaug zog, kub ib ce thiab mob ntshav qab zib. Raws li txoj cai, lawv yog ib ntus. Ua ntej siv, nws yog qhov yuav tsum tau soj ntsuam cov ncauj lus ntawm ampoule. Yog tias cov nag lossis daus tau tsim, cov kua tauv huab, cov tshuaj siv tsis tau.

“Protafan NM Penfill” - raug tshem tawm rau kev tswj hwm hauv qab daim tawv nqaij. Thaum so, daim ntawv dawb nag lossis daus uas ua kom yaj nrog kev tshee. Cov tshuaj yeeb dej caw yog tib neeg insulin, tsim nyob rau hauv txoj kev biotechnological Cov tshuaj yog txhaj rau hauv tus ncej puab, plab, pob tw lossis xub pwg. Qhov nqus nrawm tshwm sim tom qab kev txhaj tshuaj rau hauv peritoneum.

Cov tshuaj no tuaj yeem siv nyob rau thaum cev xeeb tub, vim tias insulin tsis hla lub cev thiab tsis tuaj yeem tsim kev puas tsuaj rau tus menyuam hauv plab. Ntawm qhov tsis sib xws, hyperglycemia yam tsis muaj kev kho kom zoo yuav ua rau muaj kev noj qab haus huv ntawm tus menyuam. Yog tias tus neeg mob mob siab mob rau daim siab lossis mob raum, nws yog qhov yuav tsum tau txo qhov ntau npaum li cas ntawm cov tshuaj. Kev ua xua rau feem ntau yog hauv zos. Cov kev mob tshwm sim kuj tuaj yeem mus dhau lawv tus kheej thiab tsis tas yuav siv koob tshuaj hloov kho tshuaj.

Nws yog ib qho tseem ceeb kom nco ntsoov tias tsuas yog kws kho mob tuaj yeem sau tshuaj rau cov tshuaj insulin thiab nws qhov ntau npaum li cas. Kev hloov ntawm ib cov tshuaj rau lwm qhov yuav tsum tau ua nyob rau hauv kev saib xyuas mob. Cov neeg mob ntshav qab zib yuav tsum paub tias kev kho mob tiav tau ua rau peb lub ntsiab lus: kev noj zaub mov noj, ua kom lub cev thiab kho tshuaj. Tsis noj zaub mov los yog thauj khoom ntau dhau yuav ua rau lub qog ua kom ntshav qab zib. Txhua yam pauv hloov ntawm kev noj qab haus huv yuav tsum ceeb toom rau tus kws kho mob uas koom nrog lub sijhawm.

Mob ntshav qab zib ib txwm ua rau neeg tuag taus. Muaj ntshav qab zib ntau dhau yog qhov txaus ntshai heev.

Aronova S.M. muab cov lus qhia txog kev kho mob ntshav qab zib. Nyeem tag nrho

Qib kev huv huv

Nyob ntawm qhov xav tau ntawm kev ua kom huv ntawm cov tshuaj hormones-yam muaj sia, kev faib tawm hauv qab no:

• Cov cuab yeej ib txwm yog ua rau cov tshuaj ua kua ntau nrog acidic ethanol, thiab tom qab ntawd nqa tawm cov lim pom, qab ntsev thiab tawm ntau ntau zaus. Txoj kev ntxuav tu tsis zoo, vim tias qhov ntau ntawm qhov tsis zoo nyob rau hauv cov tshuaj sib xyaw.
• Monopik siv yeeb tshuaj - hauv thawj theem ntawm kev ntxuav kom huv siv cov txheej txheem qub, thiab tom qab ntawd lim siv ib cov gel tshwj xeeb. Cov qib ntawm impurities tsawg dua nrog thawj txoj kev.
• Monocomponent khoom - sib sib zog nqus tu yog siv los ntawm molecular sieving thiab ion txauv chromatography, uas yog qhov kev xaiv zoo tshaj plaws rau tib neeg lub cev.

Cov tshuaj Hormonal yog tus qauv rau kev ceev ntawm kev txhim kho cov txiaj ntsig thiab lub sijhawm ua:

• ua vauv
• luv
• nruab nrab sijhawm
• ntev (txuas ntxiv)
• ua ke (ua ke).

Tus txheej txheem ntawm lawv cov kev ua tuaj yeem sib txawv, uas tus kws tshwj xeeb coj mus rau hauv kev txiav txim siab thaum xaiv cov tshuaj rau kev kho mob.

Ua raws li cov koob tshuaj thiab lub sijhawm ntawm kev tswj hwm ntawm insulin yog lub hauv paus ntawm kev ua tau zoo ntawm kev kho

Ultrashort

Tsim los txo cov ntshav qab zib kom sai. Cov hom tshuaj insulin no tau tswj hwm ua ntej noj mov, vim tias kev siv tshwm sim hauv thawj 10 feeb. Kev ua haujlwm tshaj plaws ntawm cov tshuaj tshwm sim, tom qab ib teev thiab ib nrab.

Qhov tsis zoo ntawm cov pab pawg yog lawv lub peev xwm los ua tsawg dua li kev coj tus kheej thiab kev cia siab tias cov piam thaj tsawg dua piv nrog cov neeg sawv cev nrog luv.

Nws yuav tsum nco ntsoov tias ultrashort hom tshuaj muaj zog dua.

1 PIECE (chav ntsuas ntawm kev ntsuas ntawm insulin hauv kev npaj) ntawm ultrashort hormone yog tuaj yeem txo cov ntshav qabzib 1.5-2 zaug muaj zog dua 1 PIECE ntawm cov neeg sawv cev ntawm lwm pab pawg.

Ib qho piv txwv ntawm tib neeg cov tshuaj insulin thiab ib tus neeg sawv cev ntawm pab pawg ua haujlwm ultrashort. Nws txawv ntawm lub hauv paus hormone nyob rau hauv qhov kev txiav txim ntawm kev npaj ntawm qee cov amino acids. Lub sijhawm tiv thaiv tuaj yeem ncav cuag 4 teev.

Siv rau cov ntshav qab zib hom 1, intolerance mus rau tshuaj ntawm lwm pab pawg, mob insulin tsis haum hauv ntshav qab zib hom 2, yog tias siv tshuaj hauv qhov ncauj tsis ua haujlwm.

Ultrashort tshuaj raws li cov tshuaj insulin aspart. Muaj cov tshuaj tsis muaj xim nyob rau hauv cov xaum qhwv. Txhua tus tuav 3 ml ntawm cov khoom hauv qhov sib npaug ntawm 300 tawm ntawm insulin. Nws yog ib qho piv txwv ntawm cov tib neeg cov tshuaj hormones synthesized los ntawm kev siv ntawm E. coli. Cov kev tshawb fawb tau qhia txog qhov muaj peev xwm ntawm kev muab tshuaj rau cov poj niam thaum lub sijhawm yug tus menyuam.

Muaj dua lwm tus neeg sawv cev ntawm pab pawg. Siv los kho cov neeg laus thiab menyuam yaus tom qab 6 xyoo. Siv nrog ceev faj hauv kev kho mob ntawm kev xeeb tub thiab cov laus. Kev muab tshuaj yog muab rau tus kheej. Nws yog txhaj subcutaneously lossis siv qhov tshwj xeeb twj-ua haujlwm.

Txoj kev npaj luv luv

Cov sawv cev ntawm cov pab pawg no yog tus cwj pwm tau los ntawm qhov tseeb tias lawv cov yeeb yam pib hauv 20-30 feeb thiab kav ntev li 6 teev. Cov tshuaj insulins luv luv yuav tsum muaj kev tswj hwm 15 feeb ua ntej ua zaub mov noj. Ob peb teev tom qab txhaj tshuaj, nws raug nquahu kom ua “khoom txom ncauj me”.

Hauv qee qhov kev sim kho mob, cov kws kho mob tshwj xeeb sib xyaw siv cov kev npaj luv nrog insulins ntev ntev. Ntsuam xyuas ua ntej tus neeg mob tus mob, lub xaib ntawm cov thawj coj ntawm cov tshuaj hormones, ntau npaum li cas thiab cov piam thaj.

Glucose tswj - ib feem tas li ntawm kev kho insulin

Cov sawv cev nto moo tshaj plaws:

• Actrapid NM yog ib qho tshuaj tiv thaiv kab mob tshuaj uas tau txais tshuaj subcutaneously thiab tshuaj cev nqaij. Intramuscular thawj coj kuj tseem ua tau, tab sis tsuas yog qhia los ntawm kws tshwj xeeb. Nws yog cov tshuaj kho mob.
• "Humulin tsis tu ncua" - yog tau tshaj tawm rau cov ntshav qab zib insulin-tiv thaiv kab mob, kev tiv thaiv kab mob tshiab thiab lub sijhawm muaj menyuam hauv cev nrog cov tshuaj insulin-ywj siab. Muab tej khoom nruab nrog cev, tso ntshav thiab tso ntshav tshuaj yog tau. Muaj nyob hauv lub thawv thiab cov taub.
• Humodar R yog tshuaj ib nrab hluavtaws uas tuaj yeem ua ke nrog nruab nrab-ua yeeb yam insulins. Tsis muaj kev txwv rau kev siv thaum cev xeeb tub thiab lactation.
• "Monodar" - yog tshaj tawm rau cov kab mob ntawm hom 1 thiab 2, kev tawm tsam rau cov ntsiav tshuaj, thaum lub sijhawm cev xeeb tub. Nqaij npuas monocomponent npaj.
• "Biosulin R" yog ib hom kev tsim kho caj ces hauv cov khoom muaj nyob rau hauv lub raj mis thiab daim cartridges. Nws tau ua ke nrog "Biosulin N" - insulin ntawm nruab nrab ncua sijhawm ua.

Cov tshuaj "Ntev" ntev

Qhov pib ntawm kev nqis tes ntawm cov nyiaj tsim tawm tom qab 4-8 teev thiab tuaj yeem ntev txog 1.5-2 hnub. Qhov kev ua tau zoo tshaj plaws yog pom nyob ntawm 8 thiab 16 teev txij li lub sijhawm txhaj.

Cov tshuaj yog belongs rau high-nqi insulins. Cov tshuaj nquag hauv cov muaj pes tsawg leeg yog insulin glargine. Nrog kev ceev faj yog sau tseg thaum cev xeeb tub. Siv tsis kho mob ntshav qab zib hauv menyuam yaus hnub nyoog qis dua 6 xyoo tsis pom zoo. Nws tau muab tshuaj tawm rau sab hauv ib hnub ib zaug tib lub sijhawm.

Cov xaum xaum nrog lub pob nyem uas hloov tau - ib qho yooj yim thiab ntxiv koob tshuaj

"Insulin Lantus", uas muaj lub zog ua haujlwm ntev, siv los ua ib qho yeeb tshuaj thiab muaj kev sib xyaw nrog lwm cov tshuaj tsim los txo cov ntshav qab zib. Muaj nyob hauv koob txhaj tshuaj thiab lub taub hau rau cov twj tso kua mis. Nws yog tso tawm los ntawm cov tshuaj noj.

Levemir Penfill

Cov tshuaj uas sawv cev los ntawm insulin detemir. Nws cov kab xev yog Levemir Flexpen. Tsim tshwj rau kev tswj hwm subcutaneous. Ua ke nrog cov tshuaj ntsiav tshuaj, ib lub zuj zus xaiv qhov koob tshuaj.

Cov no yog cov tshuaj nyob rau hauv daim ntawv ntawm ncua kev kawm, uas suav nrog cov tshuaj insulin "luv" thiab nruab nrab ntev hauv qee qhov kev tiv thaiv. Kev siv ntawm cov peev nyiaj no tso cai rau koj los txwv tus lej ntawm cov kev txhaj tshuaj tsim nyog nyob rau hauv ib nrab. Cov sawv cev tseem ceeb ntawm cov pab pawg tau piav qhia hauv lub rooj.

Cia rau cov neeg mob

Cov tshuaj yuav tsum muab cia rau hauv tub yees lossis lub tub yees tshwj xeeb. Lub raj mis qhib tsis tuaj yeem khaws cia hauv lub xeev no ntev dua 30 hnub, txij li thaum cov khoom muag poob lawm.

Yog tias xav tau kev thauj mus los thiab tib lub sijhawm tsis muaj lub sijhawm thauj cov tshuaj hauv tub yees, koj yuav tsum muaj lub hnab tshwj xeeb nrog cov tub yees (gel lossis dej khov).

Tseem Ceeb! Tsis txhob cia ncaj qha rau cov tshuaj insulin nrog cov tub yees, vim qhov no tseem yuav ua kev puas tsuaj rau cov tshuaj ua haujlwm.

Txhua txoj kev kho tshuaj insulin raws li ntau txoj kev kho:

• Cov txheej txheem ib txwm yog los sib txuas ua ke luv thiab ntev ua yeeb tshuaj hauv qhov sib piv ntawm 30/70 lossis 40/60, feem. Lawv siv rau hauv kev kho mob ntawm cov neeg laus, cov neeg mob tsis ua haujlwm thiab cov neeg mob uas muaj kev puas siab puas ntsws, vim tias tsis tas yuav tsum tau saib xyuas tas li nyob hauv qab. Cov tshuaj tau muab tshuaj 1-2 zaug ib hnub.
• Cov txheej txheem muaj zog - koob tshuaj txhua hnub tau muab faib nruab nrab ntawm cov yeeb yaj kiab luv luv thiab ntev ntev. Qhov thib ib yog qhia tom qab zaub mov noj, thiab lub thib ob - thaum sawv ntxov thiab thaum tsaus ntuj.

Yam kev xav tau ntawm cov tshuaj insulin yog xaiv los ntawm tus kws kho mob, coj mus rau hauv tus lej ntsuas:

• cwj pwm
• lub cev cov tshuaj tiv thaiv
• tus naj npawb ntawm qhia txog yuav tsum tau
• tus naj npawb ntawm kev ntsuas ntsuas ntawm qab zib
• muaj hnub nyoog
• piam thaj ntsuas.

Yog li, niaj hnub no muaj ntau yam tshuaj ntawm kev kho mob ntshav qab zib. Ib txoj kev xaiv raug kho tau zoo thiab ua raws li cov lus qhia ntawm tus kws tshaj lij yuav pab tswj cov piam thaj hauv ib qho kev lees paub thiab ua haujlwm kom tau txais txiaj ntsig.

Nruab Nrab Sij Hawm Insulin - 56 Tshuaj

Thoob ntiaj teb lub npe: Semi hluavtaws tib neeg insulin-isophan (Insulin-isophan tib neeg semisynthetic)

Daim ntawv noj tshuaj: subcutaneous kev ncua

Pharmacological kev txiav txim: Nruab nrab-insulin. Txo cov concentration ntawm cov piam thaj hauv cov ntshav, ua rau nws nqus tau los ntawm cov ntaub so ntswg, txhim kho lipogenesis ...

Kev Taw Qhia: Hom 2 mob ntshav qab zib mellitus, hom 2 mob ntshav qab zib mellitus, theem ntawm kev tawm tsam tshuaj rau qhov ncauj hypoglycemic, ib feem tawm tsam qhov ncauj ...

Thoob ntiaj teb lub npe: Semi hluavtaws tib neeg insulin-isophan (Insulin-isophan tib neeg semisynthetic)

Daim ntawv noj tshuaj: subcutaneous kev ncua

Pharmacological kev txiav txim: Nruab nrab-insulin. Txo cov concentration ntawm cov piam thaj hauv cov ntshav, ua rau nws nqus tau los ntawm cov ntaub so ntswg, txhim kho lipogenesis ...

Kev Taw Qhia: Hom 2 mob ntshav qab zib mellitus, hom 2 mob ntshav qab zib mellitus, theem ntawm kev tawm tsam tshuaj rau qhov ncauj hypoglycemic, ib feem tawm tsam qhov ncauj ...

Thoob ntiaj teb lub npe: Semi hluavtaws tib neeg insulin-isophan (Insulin-isophan tib neeg semisynthetic)

Daim ntawv noj tshuaj: subcutaneous kev ncua

Pharmacological kev txiav txim: Nruab nrab-insulin. Txo cov concentration ntawm cov piam thaj hauv cov ntshav, ua rau nws nqus tau los ntawm cov ntaub so ntswg, txhim kho lipogenesis ...

Kev Taw Qhia: Hom 2 mob ntshav qab zib mellitus, hom 2 mob ntshav qab zib mellitus, theem ntawm kev tawm tsam tshuaj rau qhov ncauj hypoglycemic, ib feem tawm tsam qhov ncauj ...

Thoob ntiaj teb lub npe: Semi hluavtaws tib neeg insulin-isophan (Insulin-isophan tib neeg semisynthetic)

Daim ntawv noj tshuaj: subcutaneous kev ncua

Pharmacological kev txiav txim: Nruab nrab-insulin. Txo cov concentration ntawm cov piam thaj hauv cov ntshav, ua rau nws nqus tau los ntawm cov ntaub so ntswg, txhim kho lipogenesis ...

Kev Taw Qhia: Hom 2 mob ntshav qab zib mellitus, hom 2 mob ntshav qab zib mellitus, theem ntawm kev tawm tsam tshuaj rau qhov ncauj hypoglycemic, ib feem tawm tsam qhov ncauj ...

Thoob ntiaj teb lub npe: Semi hluavtaws tib neeg insulin-isophan (Insulin-isophan tib neeg semisynthetic)

Daim ntawv noj tshuaj: subcutaneous kev ncua

Pharmacological kev txiav txim: Nruab nrab-insulin. Txo cov concentration ntawm cov piam thaj hauv cov ntshav, ua rau nws nqus tau los ntawm cov ntaub so ntswg, txhim kho lipogenesis ...

Kev Taw Qhia: Hom 2 mob ntshav qab zib mellitus, hom 2 mob ntshav qab zib mellitus, theem ntawm kev tawm tsam tshuaj rau qhov ncauj hypoglycemic, ib feem tawm tsam qhov ncauj ...

Thoob ntiaj teb lub npe: Semi hluavtaws tib neeg cov kua dej-isophan (Insulin-isophan tib neeg semisynthetic)

Daim ntawv noj tshuaj: subcutaneous kev ncua

Pharmacological kev txiav txim: Nruab nrab-insulin. Txo cov concentration ntawm cov piam thaj hauv cov ntshav, ua rau nws nqus tau los ntawm cov ntaub so ntswg, txhim kho lipogenesis ...

Kev Taw Qhia: Hom 2 mob ntshav qab zib mellitus, hom 2 mob ntshav qab zib mellitus, theem ntawm kev tawm tsam tshuaj rau qhov ncauj hypoglycemic, ib feem tawm tsam qhov ncauj ...

Thoob ntiaj teb lub npe: Kev tsim kho tshuab hauv tshuab hlwb hlau insulin-isophan (Insulin-isophan tib neeg kev lom neeg lub cev)

Daim ntawv noj tshuaj: subcutaneous kev ncua

Pharmacological kev txiav txim: Nruab nrab-insulin. Txo cov concentration ntawm cov piam thaj hauv cov ntshav, ua rau nws nqus tau los ntawm cov ntaub so ntswg, txhim kho lipogenesis ...

Kev Taw Qhia: Hom 2 mob ntshav qab zib mellitus, hom 2 mob ntshav qab zib mellitus, theem ntawm kev tawm tsam tshuaj rau qhov ncauj hypoglycemic, ib feem tawm tsam qhov ncauj ...

Thoob ntiaj teb lub npe: Nqaij npuas insulin-zinc monocomponent compound ncua kev kawm (Insulin-zinc nqaij npuas monocomponent compound ncua kev kawm)

Daim ntawv noj tshuaj: subcutaneous kev ncua

Pharmacological kev txiav txim: Tus neeg sawv cev hypoglycemic, nruab nrab ua yeeb yam insulin. Cuam tshuam nrog ib qho tshwj xeeb receptor rau ntawm daim nyias nyias ...

Kev Taw Qhia: Yam 1 ntshav qab zib mellitus (insulin-dependant). Yam 2 ntshav qab zib mellitus (non-insulin-dependant): theem ntawm tsis kam mus rau qhov ncauj hypoglycemic ...

Thoob ntiaj teb lub npe: Semi hluavtaws tib neeg cov kua dej-isophan (Insulin-isophan tib neeg semisynthetic)

Daim ntawv noj tshuaj: subcutaneous kev ncua

Pharmacological kev txiav txim: Nruab nrab-insulin. Txo cov concentration ntawm cov piam thaj hauv cov ntshav, ua rau nws nqus tau los ntawm cov ntaub so ntswg, txhim kho lipogenesis ...

Kev Taw Qhia: Hom 2 mob ntshav qab zib mellitus, hom 2 mob ntshav qab zib mellitus, theem ntawm kev tawm tsam tshuaj rau qhov ncauj hypoglycemic, ib feem tawm tsam qhov ncauj ...

Kev Tso Tshuaj insulin: Cov Tshuaj Tshuaj Rooj

Cov tshuaj Insulin yog qhov tsis tuaj yeem uas yog ib feem ntawm cov tshuaj siv hauv tshuaj kho kom muaj kev ruaj ntseg ntawm cov neeg mob ntshav qab zib mellitus thiab lwm yam kab mob sib kis - tshwj xeeb, ko taw mob ntshav qab zib.

Pom qhov txawv ntawm ntuj thiab hluavtaws insulin, thawj zaug yog ib qho tshuaj hormones tsim los ntawm cov txiav ua neeg los yog tsiaj nyeg.

Qhov thib ob yog tsim hauv chav kuaj los ntawm kev sib txuas ntawm cov tshuaj tseem ceeb uas siv cov khoom siv ntxiv. Nws yog nyob ntawm nws lub hauv paus uas qhov kev npaj tshuaj insulin tau tsim.

Lwm hom insulin dab tsi muaj thiab los ntawm cov cim qhia cov tshuaj xa tuaj, lawv faib yog dab tsi? Txij li thaum cov neeg mob xav tau kev txhaj tshuaj ntau zaus hauv ib hnub, nws yog ib qho tseem ceeb kom paub thiaj li xaiv cov kev xaiv ua kom zoo, kev tshwm sim thiab ua yeeb tshuaj - tsis ua rau muaj kev fab tshuaj thiab lwm cov kev mob tshwm sim uas tsis xav tau.

Hom mob insulin

Kev faib tawm cov nyiaj tau los raws li cov ntsiab hauv qab no:

• Kev ceev ntawm kev txiav txim tom qab tswj hwm
• Sijhawm ntawm kev ua
• Keeb Kwm
• Daim ntawv tso tawm.

Raws li qhov no, tsib yam tseem ceeb ntawm insulin txawv.

1. Yooj yim lossis ultrashort ua yeeb yam sai.
2. Cov tshuaj insulin luv luv.
3. Cov tshuaj insulin nrog qhov nruab nrab lub sijhawm siv.
4. Lub sijhawm ntev lossis ua kom ntev ntev tiv thaiv cov tshuaj insulin.
5. Cov tshuaj Insulin sib xyaw ua ke thiab ntev heev suav nrog.

Cov txheej txheem ntawm kev ua ntawm txhua hom tshuaj hormones yog txawv, thiab tsuas yog tus kws tshaj lij tuaj yeem txiav txim siab hom insulin thiab qhov twg yuav zoo rau tus neeg mob.

Lub hom phiaj ntawm cov tshuaj ntawm cov yam xav tau yuav ua raws li daim ntawv ntawm tus kab mob, nws qhov mob hnyav, lub hnub nyoog thiab tus kheej ntawm lub cev yam ntxwv ntawm tus neeg mob. Txhawm rau ua qhov no, ntau cov kev sim tau raug coj tawm, keeb kwm kev kho mob thiab cov duab hauv chaw kho mob ntawm lwm cov kab mob ntev hauv keeb kwm tau ua tib zoo kawm.

Qhov ntxim nyiam ntawm kev phiv yog tseem coj mus rau hauv tus account, tshwj xeeb tshaj yog yog hais tias cov tshuaj raug txwv rau cov neeg laus lossis menyuam yaus. Yog li, nws yog ib qho tseem ceeb kom paub txog cov yam ntxwv ntawm txhua hom tshuaj ua ntej koj pib noj nws.

Cov tshuaj insulin ultrasonic

Hom khoom no pib ua nws cov haujlwm tam sim ntawd, tam sim ntawd tom qab qhia rau hauv cov ntshav, tab sis lub sijhawm ntawm nws qhov kev ua haujlwm kuj tsawg - txog 3-4 teev. Qhov siab tshaj plaws ntawm cov kab mob ultrashort insulin hauv lub cev tau mus txog ib teev tom qab kev txhaj tshuaj.

Cov yam ntxwv thov: cov tshuaj tau hais kom nruj ua ntej lossis tam sim ntawd tom qab noj mov, tsis hais lub sijhawm nruab hnub. Txwv tsis pub, ib qho kev hem thawj ntawm hypoglycemia yuav tshwm sim.

Cov kev mob tshwm sim: yog tias lawv tsis tshwm sim tam sim ntawd tom qab kev tswj hwm, lawv tsis tshwm sim tom qab, txawm tias qhov tseeb hais tias yuav luag txhua cov tshuaj ntawm hom no hloov caj ces thiab tuaj yeem ua rau muaj kev tsis haum tshuaj nrog rau ib tus neeg tsis kam ua rau lub Cheebtsam.

Hauv cov khw muag tshuaj, hom kab mob insulin no tau qhia nyob rau hauv daim ntawv ntawm cov tshuaj hauv qab no, cov npe:

1. "Insulin Apidra",
2. "Insulin Humalog"
3. Novo-nrawm.

Cov tshuaj insulin luv luv

Qhov hom khoom no pib cuam tshuam rau lub cev tsis pub dhau 30 feeb tom qab kev tswj hwm, tab sis tsis tau ua ntej 20 feeb. Qhov siab tshaj plaws tau pom nyob rau thaj tsam 2-3 teev tom qab kev tswj hwm, thiab tuaj yeem ntev txog 6 teev.

Cov yam ntxwv ntawm kev thov: Nws raug nquahu kom qhia cov tshuaj tam sim ua ntej noj mov. Hauv qhov no, nruab nrab ntawm kev txhaj tshuaj thiab thaum pib noj mov, ncua sijhawm tsawg kawg 10-15 feeb yuav tsum pom.

Qhov no yog ua kom lub ncov siab tshaj plaws rau qhov tshuaj sib txuam ua ke hauv lub sijhawm nrog kev nkag mus rau hauv lub cev thiab kev nqus ntawm cov as-ham.

Tom qab ob peb teev, thaum insulin mus txog nws qhov kev xav ntau, yuav tsum muaj lwm pluas mov me me - khoom noj txom ncauj.

Cov kev mob tshwm sim: pom tsis tshua muaj, txawm tias siv ntev, tsis hais seb cov khoom puas hloov kho los yog hloov.

Cov tshuaj insulin luv luv muaj muag rau qhov tshuaj Insulin Actrapid thiab Humulin Tsis tu ncua.

Nruab Nrab Sijhawm Insulin

Pab pawg no suav nrog cov tshuaj thiab hom tshuaj insulin, lub sijhawm kis ntawm 12 los ntawm 16 teev. Qhov tseeb tshwm sim tom qab kev tswj hwm tau pom tsuas yog tom qab 2-3 teev, qhov siab tshaj plaws tau mus txog tom qab 6 teev, vim tias feem ntau sib nrug ntawm kev txhaj tshuaj tsis tshaj 12 teev, thiab qee zaum tsuas yog 8-10.

Cov yam ntxwv ntawm kev taw qhia: 2-3 hno tshuaj insulin ib hnub yog qhov txaus, tsis hais noj mov dab tsi. Feem ntau, nrog rau ib qho kev txhaj tshuaj, ib koob tshuaj luv luv ntawm lub cev insulin kuj raug tswj hwm, cov tshuaj tau ua ke.

Cov kev mob tshwm sim: tsis muaj, tsis hais txog kev tswj hwm lub sijhawm, vim tias cov tshuaj cuam tshuam rau lub cev loj dua, tab sis qeeb dua hauv kev sib piv nrog rau lwm hom.

Cov tshuaj yeeb yaj kiab uas nrov tshaj plaws nrog hom insulin no yog: “Insulan Humulin NPH”, “Humodar br” thiab Protulin insulin.

Lwm txoj kev faib

Kev faib tawm ntawm cov tshuaj insulin hauv txoj kev no yog nqa tawm los ntawm nws lub keeb kwm. Nws muaj ntau hom:

1. Hormone tivthaiv ntawm nyuj - ib yam khoom uas rho tawm los ntawm tus kabmob txiav tawv tsiaj. Hom insulin no ntau zaus ua rau muaj kev tsis haum tshuaj, vim nws txawv ntawm cov keeb tsim los ntawm tib neeg lub cev. Qhov no suav nrog Insulap GLP thiab Ultralent, cov tshuaj tseem muaj hauv cov ntawv hauv ntsiav tshuaj,
2. Hormonal nqaij npuas ua. Cov tshuaj no sib txawv ntawm tib neeg cov kua dej hauv ib pawg ntawm cov amino acids, tab sis qhov no txaus los ua kev fab tshuaj.

Cov ntaub ntawv siv tau: txhua yam ntawm cov tshuaj no muaj nyob rau hauv cov tshuaj siv tshuaj lom neeg ntev.

Ob qho nram qab no:

• Hloov kho txhob kaw. Nws yog tsim nyob rau hauv lub hauv paus ntawm lub tshuaj ntawm tib neeg keeb kwm siv Escherichia coli.
• Kev tsim kho tshuab Hauv qhov no, qhov sib xyaw ntawm cov keeb kwm ntawm porcine yog siv los ua lub hauv paus, thaum lub mismatched amino acid saw hloov.

Qhov kev xaiv kawg ntawm hom thiab hom kev npaj tshuaj insulin yog ua rau lub hauv paus ntawm kev txheeb xyuas ntawm kev tawm tsam ntawm lub cev thiab tus neeg mob tom qab txhaj ntau.

Raws li kev xav ib qho tsis txaus siab ntawm cov kws kho mob thiab cov kws tshawb nrhiav, cov tshuaj insulin tau siv tib neeg lub cev, hloov kho lossis hloov kho, suav tias yog qhov zoo dua. Hom no suav nrog insulin isophan.

Nws yog hom tshuaj no tsawg kawg uas yuav ua rau muaj kev tsis haum tshuaj, vim tias tsis muaj protein nyob hauv nws cov lus, thiab muab cov txiaj ntsig tau sai thiab kav ntev, uas yog qhov ntsuas tseem ceeb rau kev tswj hwm tus neeg mob lub xeev ruaj khov.

Cov yeeb yaj kiab quav yeeb tshuaj

Cov nyhuv tseem ceeb ntawm cov kua dej yog qhov txo qis hauv cov piam thaj hauv ntshav. Tab sis muaj cov tshuaj uas, ntawm qhov tsis tooj, nce nws qib - lawv hu ua kev thaiv kev. Cov Insulin Antagonist:

1. Glucagon.
2. Adrenaline thiab lwm yam catecholamines.
3. Cortisol thiab corticosteroids.
4. Kev loj hlob qog thiab tshuaj hormones.
5. Thyroxine, triiodothyronine thiab lwm cov thyroid hormones.

Tag nrho cov tshuaj no ua rau cov tshuaj insulin txawv txav, uas yog, nce ntxiv ntshav qab zib cov ntshav. Lawv cov txiaj ntsig ntawm lub cev tuaj yeem yog lub sijhawm ntev heev, txawm hais tias qhov tseeb tias cov mechanism tau kawm txog qee qhov qis dua li cov kua dej.

Nta thiab sib txawv ntawm cov tshuaj, rooj

Kev txhaj koob tshuaj yog tsim rau hauv tus ncej puab cov leeg, vim tias qhov nqus ntawm cov tshuaj yuav qeeb heevQhov kev txhaj tshuaj yog tsim rau hauv lub plab, vim cov tshuaj pib tshwm sim tam sim ntawd Sij hawm siv

Yog tias ua tau, cov tshuaj insulin yuav tsum muab sijhawm sib luag thaum sawv ntxov thiab yav tsaus ntuj, thaum sawv ntxov, nrog rau kev txhaj "insulin ntev, kev txhaj tshuaj ntawm" luv "Cov tshuaj tau muab rau noj li 20-30 feeb ua ntej txhua pluas noj Cov zaub mov khi

Cov tshuaj tau siv tsis hais kev noj zaub movTxhawm rau zam kom tsis txhob muaj ntshav qab zib, tom qab txhua txoj kev tswj hwm ntawm hom insulin no, noj mov lossis tsawg kawg tsawg cov khoom noj txom ncauj me.

Cov tshuaj insulin: cov npe, cov chaw muag tshuaj thiab cov haujlwm ntawm kev coj ua

Lub International Diabetes Federation kwv yees hais tias txog xyoo 2040 tus naj npawb ntawm cov neeg mob ntshav qab zib yuav muaj li 624 lab tus tib neeg. Tam sim no, 371 lab tib neeg raug mob los ntawm tus kab mob.

Kev sib kis ntawm tus kab mob no cuam tshuam nrog kev hloov pauv hauv tib neeg txoj kev ua neej (kev ua neej nyob rau lub neej tsis txaus siab, tsis muaj lub cev ua si) thiab ua zaub mov noj (siv cov khoom siv hauv khw muag tshuaj muaj nplua nuj nyob hauv cov tsiaj rog).

Nyob rau tib lub sijhawm, ua tsaug rau kev siv cov tshuaj uas muaj suab thaj ntau, kev soj ntsuam lub sijhawm ntawm tus kabmob, thiab kev tsim kho tshiab los ntawm cov kws tshawb fawb hauv thaj chaw no, qhov nruab nrab lub neej ntawm cov neeg mob tau pib nce ntxiv.

Tib neeg tau paub txog tus mob ntshav qab zib tau ntev los lawm, tab sis qhov tshwm sim ntawm txoj kev kho tus mob no tsuas tshwm sim txog ib puas xyoo dhau los, thaum kev kuaj mob zoo li no ploj tuag.

Keeb kwm ntawm kev tshawb pom thiab tsim kom muaj cov tshuaj insulin

Xyoo 1921, Canadian tus kws kho mob Frederick Bunting thiab nws tus pab cuam, kws kho mob, Charles Zoo, sim nrhiav kev sib txuas ntawm tus txiav thiab pib mob ntshav qab zib. Txog kev tshawb nrhiav, tus xibfwb ntawm University of Toronto, John MacLeod, tau muab rau lawv kuaj nrog rau cov cuab yeej tsim nyog thiab 10 tus dev.

Cov kws kho mob tau pib ua lawv txoj kev sim los ntawm kev tshem tawm txoj kev txiav txim siab ntawm qee tus dev, hauv seem lawv tau muab cov ntaub qhwv txiav tawm ua ntej tshem tawm. Tom ntej no, qhov hloov khoom nruab nrog atrophied tau tso rau khov rau hauv kev daws hypertonic. Tom qab txhaws, cov tshuaj tawm (insulin) tau muab rau cov tsiaj nrog lub qog tshem tawm thiab lub tsev kho mob ntshav qab zib.

Raws li qhov txiaj ntsig ntawm qhov no, qhov kev txo qis hauv cov ntshav qab zib thiab kev txhim kho hauv cov xwm txheej thiab kev noj qab haus huv ntawm tus dev tau sau tseg. Tom qab ntawd, cov kws tshawb nrhiav tau txiav txim siab sim ua kom muaj cov kua dej los ntawm cov kua dej me me ntawm cov plab hlaub thiab pom tias koj tuaj yeem ua yam tsis muaj kev hla ntawm cov ducts. Tus txheej txheem no tsis yooj yim thiab siv sijhawm.

Bunting thiab Zoo Tshaj tau pib ua qhov kev sim rau cov neeg nrog lawv tus kheej. Raws li kev soj ntsuam sim, nkawd ob leeg hnov ​​kiv thiab tsis muaj zog, tab sis tsis muaj teeb meem loj los ntawm cov tshuaj.

14-xyoo-laus tub Leonard Thompson yog thawj tus neeg mob tau txais kev txhaj tshuaj ntawm cov tshuaj insulin. Tom qab thawj zaug txhaj tshuaj, tus neeg mob tsis tau zoo, tab sis kev pheej rov qab txo qis cov ntshav qabzib hauv cov ntshav thiab txhim kho kev nyab xeeb ntawm tus tub. Nws yog thawj tus neeg mob rau cov tshuaj tua kab mob cawm nws txoj sia. Thaum lub sijhawm ntawm kev txhaj tshuaj, qhov hnyav ntawm tus menyuam yog 25 kg. Tom qab ntawd, nws ua neej nyob dua 13 xyoos thiab tuag ntawm mob ntsws qhuav.

Hauv xyoo 1923, Frederick Butting thiab John MacLeod tau txais qhov Nobel nqi zog rau insulin.

Dab tsi yog insulin ua los ntawm?

Kev npaj tshuaj insulin yog tau los ntawm cov khoom siv ntawm tsiaj los yog tib neeg keeb kwmCov. Hauv thawj kis, cov txiav txiav npua los yog nyuj yog siv. Lawv feem ntau ua rau ua xua, yog li lawv tuaj yeem ua rau txaus ntshai. Qhov no muaj tseeb tshwj xeeb tshaj yog rau bovine insulin, qhov muaj pes tsawg leeg yog qhov sib txawv ntawm tib neeg (peb cov amino acids tsis dhau ib qho).

Cov tshuaj insulin tau los ntawm kab mob npua muaj peev xwm zoo ib yam li cov qauv qub, thiab feem ntau siv rau hauv kev kho mob ntshav qab zib.

Muaj ob hom kev npaj rau cov insulin:

• semi-hluavtaws
• zoo li tib neeg.

Tib neeg cov insulin yog tau los ntawm kev siv caj ces tsim hluav taws xob. siv cov enzymes ntawm cov poov xab thiab cov kab mob E. coli.

Nws yog qhov zoo tshaj plaws nyob rau hauv muaj pes tsawg leeg rau cov tshuaj hormones tsim los ntawm cov txiav. Ntawm no peb tab tom tham txog kev hloov pauv hloov caj dab E. coli, uas muaj peev xwm tsim cov txiv neej insulin hloov caj ces.

Insulin Actrapid yog thawj cov tshuaj hormones uas tau los ntawm kev tsim caj ces.

Semi-hluav taws xob cov tshuaj hormones yog tsim los ntawm kev ua tiav ntawm kev txu cov kab mob ntshav los ntawm cov enzymes tshwj xeeb. Hauv kev tsim cov kev npaj los ntawm cov tsiaj, lawv tau muab ntxuav kom huv. Qhov tseeb meej dua ntawm hom no yog qhov tsis muaj kev ua xua thiab kev sib raug zoo nrog tib neeg lub cev.

Kev cais tawm cov Insulin

Ntau hom insulin hauv kev kho mob ntshav qab zib sib txawv ntawm txhua lwm yam hauv ntau txoj kev:

1. Lub sijhawm raug ncua ntev.
2. Kev ceev ntawm kev txiav txim tom qab tswj hwm tshuaj.
3. Daim ntawv tso tawm ntawm cov tshuaj.

Raws li lub sijhawm ua rau muaj kev tiv thaiv, kev npaj tshuaj insulin yog:

• ultrashort (ceev tshaj plaws)
• luv
• nruab nrab-ntev
• ntev
• ua ke

Cov tshuaj Ultrashort (insulin apidra, insulin humalog) yog tsim los kom sai cov ntshav qab zib. Lawv tau qhia ua ntej noj mov, qhov tshwm sim ntawm cov nyhuv tshwm sim nws tus kheej tsis pub dhau 10-15 feeb. Tom qab ob peb teev, cov nyhuv ntawm cov tshuaj dhau los ua cov nquag.

Cov tshuaj yeeb yaj kiab luv luv (insulin actrapid, insulin sai)pib ua haujlwm li ib nrab teev tom qab tswj hwm. Lawv lub sijhawm yog 6 teev. Nws yog ib qho tsim nyog kom tswj cov insulin 15 feeb ua ntej noj mov. Qhov no yog qhov tsim nyog thiaj li hais tias lub sijhawm ntawm kev nqus ntawm cov khoom noj muaj txiaj ntsig hauv lub cev haum nrog lub sijhawm ntawm kev sib xyaw nrog tshuaj.

Taw qhia cov tshuaj nruab nrab (insulin protafan, insulin humulin, insulin basal, insulin tshiab sib xyaw) tsis yog nyob ntawm lub sijhawm noj cov zaub mov. Lub sijhawm tiv thaiv yog 8-12 teevpib ua kom nquag plias ob teev tom qab txhaj tshuaj.

Lub sijhawm ntev tshaj plaws (txog 48 teev) ntawm lub cev yog ua haujlwm dhau los ntawm kev siv sijhawm ntev ntawm kev npaj tshuaj insulin. Nws pib ua haujlwm plaub mus rau yim teev tom qab kev tswj hwm (tresiba insulin, flekspen insulin).

Kev npaj ua ke yog kev sib xyaw ua ke ntawm cov insulins ntawm ntau yam kev txuam nrog ntev. Qhov pib ntawm lawv txoj haujlwm pib ib nrab teev tom qab txhaj tshuaj, thiab tag nrho lub sijhawm yog 14-16 teev.

Niaj hnub no cov tshuaj insulin

Ib qho ntawm cov kev ntsuas tseem ceeb rau kev xaiv qhov sib piv ntawm tib neeg cov tshuaj insulin yog tus nqi ntawm nws cov kev ua kom muaj zog hauv lub cev. Yuav luag txhua cov analogs niaj hnub no ua sai sai.

Feem ntau, ib qho tuaj yeem paub qhov txawv ntawm cov khoom zoo ntawm cov qauv ua piv txwv:

• kev siv qhov nruab nrab, tsis daws teeb meem acidic,
• lub thev naus laus zis DNA thev naus laus zis
• kev rov tshwm sim ntawm thaj chaw tshiab ua zog hauv cov tshuaj tshiab.

Cov tshuaj insulin zoo li tau tsim los ntawm kev rov cais cov amino acids los txhim kho cov tshuaj ntawm cov tshuaj, lawv qhov kev nqus thiab kev pom zoo. Lawv yuav tsum muaj peev xwm dhau ntawm tib neeg cov tshuaj insulin hauv txhua yam khoom thiab tsis muaj:

1. Insulin Humalog (Lyspro). Vim tias qhov hloov pauv ntawm tus qauv ntawm cov tshuaj insulin no, nws tau dhau los ua rau lub cev sai dua los ntawm qhov chaw txhaj tshuaj. Kev sib piv ntawm tib neeg cov insulin nrog cov humalogue qhia tau hais tias nrog kev qhia ntawm kev xav siab tshaj plaws ntawm kev sib tw tom qab tau tiav nrawm dua thiab muaj siab dua li cov concentration ntawm tib neeg. Ntxiv mus, cov tshuaj ntau dua sai sai thiab tom qab 4 teev nws cov concentration poob rau thawj tus nqi. Lwm qhov zoo dua ntawm humalogue tshaj tib neeg yog kev ywj pheej ntawm lub sijhawm ntawm kev chwv cov koob tshuaj.
2. Tshuaj Insulin Novorapid (aspart). Cov insulin no muaj lub sijhawm luv luv ntawm kev ua haujlwm nquag, uas ua rau nws muaj peev xwm tswj tau glycemia tag nrho tom qab noj mov.
3. Levemir insulin penfill (detemir). Qhov no yog ib qho ntawm hom insulin, uas yog yam ntxwv maj mam ua tiav thiab txaus siab qhov xav tau ntawm tus neeg mob ntshav qab zib mellitus rau insal basal. Qhov no yog ib qho piv txwv ntawm lub sijhawm nruab nrab, tsis muaj qhov siab tshaj.
4. Tshuaj Insulin Apidra (Glulisin). Nqa cov khoom siv rau lub cev qhov nruab nrab, cov teeb meem hauv metabolic zoo ib yam rau tib neeg cov tshuaj insulin. Haum rau kev siv ntev.
5. Glulin insulin (lantus). Nws yog tus yam ntxwv los ntawm kev tiv thaiv ultra-ntev, kom tsis muaj kev faib tawm thoob plaws lub cev. Hais txog nws cov hauj lwm zoo, insulin lantus zoo tib yam rau tib neeg cov insulin.

Insulin luv thiab Nruab Nrab - Insulin

Npe - Rosinsulin C

Chaw tsim tshuaj paus - zib ntab ua ke (Russia)

Pharmacological kev txiav txim:
Cov tshuaj yog nruab nrab ntawm nruab nrab. Kev ua ntawm cov tshuaj pib tom qab 60 -120 feeb. Qhov siab tshaj plaws tau tiav ntawm 2-12 teev tom qab kev tswj hwm. Cov nyhuv ntawm cov tshuaj no kav ntev li 18-24 teev.

Kev taw qhia rau kev siv: Insulin-cov foos ntawm cov ntshav qab zib. Kev tsis zoo rau cov ncauj lus hypoglycemic. Kev sib xyaw ua ke nrog cov tshuaj tiv thaiv qhov ncauj hypoglycemic.

Npe: Actrapid HM, Actrapid HM

Chaw tsim tshuaj paus: Novo Nordisk (Denmark), Novo Nordisk

Muaj pes tsawg leeg:

• 1 ml muaj - 40 PIECES lossis 100 PIECES.
• Cov tshuaj nquag - cov khoom zoo ib yam rau ntuj tsim insulin. Ib qho kev daws teeb meem ntawm qhov nruab nrab (pH = 7.0) insulin rau kev txhaj tshuaj (30% amorphous, 70% crystalline).

Pharmacological kev txiav txim: Nws muaj cov qauv monocomponent. Kev ua yeeb yaj kiab luv luv: cov nyhuv ntawm cov tshuaj pib tom qab 30 feeb. Qhov siab tshaj plaws tau tiav ntawm 2.5-5 teev tom qab kev tswj hwm. Cov nyhuv ntawm cov tshuaj no kav 8 teev.
(ntau tshaj ...)

Chaw tsim tshuaj paus - Tonghua Dongbao Tshuaj (Suav Teb)

Muaj pes tsawg leeg:
Soluble tib neeg cov tshuaj engineering insulin.

Pharmacological kev txiav txim: Luv ua yeeb yam insulins.

Soluble insulin (tib neeg kev paub txog engineering).

Kev taw qhia rau kev siv: Ketoacidosis, ntshav qab zib, lactic acid thiab hyperosmolar coma, insulin-tiv thaiv cov ntshav qab zib mellitus (hom I), suav nrog

nrog cov mob cuam tshuam (kev kis mob, kev raug mob, kev phais mob, kev tshem tawm cov kab mob mus ntev), mob ntshav qab zib thiab / lossis ua rau lub siab ua haujlwm tsis zoo, cev xeeb tub thiab yug menyuam, mob ntshav qab zib mellitus (hom II) nrog kev tawm tsam cov tshuaj tiv thaiv kab mob hauv lub qhov ncauj.

Chaw tsim tshuaj paus - Bryntsalov-A (Russia)

Muaj pes tsawg leeg: Semi-hluavtaws monocomponent tib neeg cov kua dej. 1 ml ntawm cov tshuaj rau txhaj yog muaj tib neeg insulin 100 IU, nrog rau 3 mg metacresol ua tshuaj tiv thaiv.

Pharmacological kev txiav txim: Kev siv tshuaj insulin ntawm kev ua sai thiab luv. Qhov kev txiav txim tsim tawm 30 feeb tom qab sc tswj, nce mus txog qhov siab nyob hauv thaj tsam ntawm 1-3 teev thiab kav ntev txog 8 teev.
(ntau tshaj ...)

Chaw tsim tshuaj paus - Bryntsalov-A (Russia)

Muaj pes tsawg leeg: Solulin nqaij npuas ua kua. 1 ml ntawm kev daws rau kev txhaj tshuaj muaj cov tshuaj zoo heev monocomponent porcine insulin 100 PIECES thiab nipagin ua tshuaj tiv thaiv 1 mg.

Pharmacological kev txiav txim: Cov tshuaj yeeb yog luv-yeeb yam. Cov nyhuv pib 30 feeb tom qab sc tswj, nce mus txog qhov siab nyob hauv thaj tsam ntawm 1-3 teev thiab kav ntev txog 8 teev.

Cov tshuaj insulin-Ferein CR

Chaw tsim tshuaj paus - Bryntsalov-A (Russia)

Muaj pes tsawg leeg: Semi-hluavtaws soluble tib neeg cov kua dej.

Pharmacological kev txiav txim: Luv ua yeeb yam insulins.
(ntau tshaj ...)

Chaw tsim tshuaj paus - Bryntsalov-A (Russia)

Muaj pes tsawg leeg: 1 ml ntawm kev txhaj tshuaj muaj cov tshuaj insulin tsis pub tib neeg 40 IU, nrog rau 3 metacresol, glycerin ua tshuaj tiv thaiv.

Pharmacological kev txiav txim: Brinsulrapi Ch - insulin luv luv.

Qhov pib ntawm kev ua ntawm cov tshuaj 30 feeb tom qab ua haujlwm subcutaneous, cov txiaj ntsig siab tshaj plaws hauv lub sijhawm nruab nrab ntawm 1 teev mus rau 3 teev, lub sijhawm ua haujlwm yog 8 teev.

Qhov profile ntawm cov tshuaj nyob ntawm qhov koob tshuaj thiab qhia qhov tseem ceeb ntawm tus neeg.
(ntau tshaj ...)

Chaw tsim tshuaj paus - Bryntsalov-Ferein (Russia)

Muaj pes tsawg leeg: 1 ml kev txhaj tshuaj muaj cov kab mob porcine heev ua kom huv monocomponent insulin

Pharmacological kev txiav txim: Luv luv ua yeeb yam insulin npaj. Cov nyhuv tsim tawm 30 feeb tom qab sc tswj, nce mus txog qhov siab nyob hauv thaj tsam ntawm 1-3 teev thiab kav ntev txog 8 teev.

Kev taw qhia rau kev siv:

• Mob ntshav qab zib mellitus (hom 1) hauv cov menyuam yaus thiab cov neeg laus
• ntshav qab zib mellitus (hom 2) (nyob rau hauv kev tiv thaiv ntawm qhov ncauj hypoglycemic, suav nrog ib nrab thaum sib koom ua ke, tawm tsam cov keeb kwm ntawm cov kab mob sib kis, thaum cev xeeb tub).

Chaw tsim tshuaj paus - Marvel LifeSinessez (Is Nrias teb) / Pharmstandard-Ufa Vitamin Cog (Russia)

Muaj pes tsawg leeg: Tib neeg cov tshuaj ntxuav hluav taws xob. Cov muaj mob siab: glycerol, metacresol, dej d / thiab.

Pharmacological kev txiav txim: Luv luv insulin.

Lub sijhawm ntawm kev ua ntawm insulin npaj feem ntau vim yog tus nqi ntawm kev nqus, uas nyob ntawm ntau yam (piv txwv, koob tshuaj, hom thiab qhov chaw ntawm kev tswj hwm), thiab yog li cov ntaub ntawv ntawm kev txiav txim ntawm insulin yog raug rau qhov txawv txav, ob qho tib si hauv tib neeg thiab tib neeg Cov. Tom qab kev tswj hwm sc, qhov pib ntawm kev ua ntawm cov tshuaj tau sau tseg tom qab kwv yees 30 feeb, cov nyhuv siab tshaj plaws yog nyob hauv qhov sib nrug ntawm 2 thiab 4 teev, lub sijhawm ua haujlwm yog 6-8 teev.

Chaw tsim tshuaj paus - Biobras S / A (Brazil)

Muaj pes tsawg leeg: Soluble insulin nqaij npuas monocomponent

Pharmacological kev txiav txim: Luv luv insulin.

Tom qab sc txhaj tshuaj, cov nyhuv tshwm sim li ntawm 20-30 feeb, nce mus txog qhov siab tshaj plaws tom qab 1-3 teev thiab kav ntev, nyob ntawm qhov koob tshuaj, 5-8 teev. Lub sijhawm ntawm cov tshuaj nyob ntawm qhov ntau npaum li cas, txoj kev, qhov chaw tswj hwm thiab muaj tus yam ntxwv tseem ceeb ntawm tus kheej Cov.

Chaw tsim tshuaj paus - Biobras S / A (Brazil)

Muaj pes tsawg leeg: Soluble nqaij npuas insulin monocomponent

Pharmacological kev txiav txim: Luv luv insulin.

Tom qab sc txhaj tshuaj, cov nyhuv tshwm sim hauv 30 feeb, nce mus txog qhov siab tshaj plaws tom qab 1-3 teev thiab txuas ntxiv, nyob ntawm qhov koob, 5-8 teev.

Chaw tsim tshuaj paus - Biobras S / A (Brazil)

Muaj pes tsawg leeg: Semi-hluavtaws soluble tib neeg cov kua dej

Pharmacological kev txiav txim: Luv luv insulin.

Tom qab sc txhaj tshuaj, cov nyhuv tshwm sim li ntawm 20-30 feeb, nce mus txog qhov siab tshaj plaws tom qab 1-3 teev thiab kav ntev, nyob ntawm qhov koob tshuaj, 5-8 teev. Lub sijhawm ntawm cov tshuaj nyob ntawm qhov ntau npaum li cas, txoj kev, qhov chaw tswj hwm thiab muaj tus yam ntxwv tseem ceeb ntawm tus kheej Cov.

Kev taw qhia rau kev siv:

• Yam 1 ntshav qab zib
• hom 2 mob ntshav qab zib mellitus: theem ntawm kev tawm tsam rau qhov ncauj hypoglycemic, ib nrab tiv taus kab mob hypoglycemic hauv qhov ncauj (kev kho ua ke)
• mob ntshav qab zib ketoacidosis, ketoacidotic thiab hyperosmolar coma
• mob ntshav qab zib hauv lub cev tsis tsaug zog, rau kev siv sib quas ntus hauv cov neeg mob ntshav qab zib mellitus tiv thaiv cov mob uas muaj qhov kub taub hau
• nrog cov kev phais yav tom ntej, kev raug mob, yug menyuam, teeb meem ntawm lub cev, ua ntej hloov mus rau kev kho nrog lub sijhawm ntev insulin npaj.

Lub Npe: Insulin db

Chaw tsim tshuaj paus - Berlin-Chemie AG (Lub Teb Chaws Yelemees)

Muaj pes tsawg leeg: 1 ml ntawm cov tshuaj rau txhaj yog muaj tib neeg insulin 100 PIECES.

Pharmacological kev txiav txim: Nws yog yeeb tshuaj luv-luv. Cov peev txheej siab tshaj plaws tsim tawm tom qab 1-3 teev thiab kav ntev li 6-8 teev.

Lub Npe: Insulin db

Chaw tsim tshuaj paus - ICN GALENIKA (Yugoslavia)

Muaj pes tsawg leeg: Qhov nruab nrab tov ntawm kev ua kom huv monocomponent porcine insulin. Cov tshuaj phiv yog monocomponent insulin tau los ntawm cov txiav ntawm npua (30% amorphous, 70% crystalline).

Pharmacological kev txiav txim: Luv luv insulin.

Kev siv tshuaj hypoglycemic (txo qis ntshav qab zib) cov tshuaj tshwm sim 30-90 feeb tom qab txhaj tshuaj, qhov siab tshaj plaws tshwm sim tom qab 2-4 teev, nrog tag nrho ntev txog li 6-7 teev tom qab txhaj tshuaj.

Lub Npe: Insulin db

Chaw tsim tshuaj paus - ICN GALENIKA (Yugoslavia)

Muaj pes tsawg leeg: Semi-hluavtaws soluble tib neeg cov kua dej.

Pharmacological kev txiav txim: Luv luv insulin.

Tom qab sc txhaj tshuaj, cov nyhuv tshwm sim li ntawm 20-30 feeb, nce mus txog qhov siab tshaj plaws tom qab 1-3 teev thiab txuas ntxiv, nyob ntawm qhov koob, 5-8 teev.