Lisinopril 20mg No. 20

Ntshav teeb meem yog ib qho ntawm cov kev kho mob ntsig txog tib neeg hnub nyoog sib txawv. Kev hloov pauv ntev lossis tsis hloov sai hauv qhov ntsuas yuav tsum tau kho nrog cov tshuaj tsim nyog. Ib qho ntawm cov tshuaj no yog Lisinopril, los ntawm cov lus qhia rau kev siv uas peb kawm ntawm dab tsi siab nws yuav tsum tau siv. Peb kuj xav txog dab tsi contraindications yuav tsum raug txiav txim siab ua ntej pib kev kho mob.

Cov lus qhia rau kev siv

Dab tsi lub siab yuav tsum lisinopril noj? Cov tshuaj muaj nyob hauv pawg ntawm ACE inhibitors. Tom qab noj cov tshuaj, vasodilation tshwm sim, yog li nws qhia rau kev kub siab. Nrog rau kev noj kom tsis tu ncua, kev ua haujlwm ntawm lub siab nqaij thiab cov ntshav khiav tau zoo tuaj, kev noj ntsev ntau ntxiv yuav raug tshem tawm ntawm lub cev. Cov tshuaj muaj txiaj ntsig txo cov diastolic thiab systolic ntsuas, thaum tsis cuam tshuam txog lub plawv dhia.

Cov tshuaj tau tso tawm hauv daim ntawv ntawm cov ntsiav tshuaj nrog ntau qhov sib txawv. Cov xim ntawm cov ntsiav tshuaj yog nyob ntawm qhov ntau npaum li cas ntawm cov tshuaj nquag. Txiv kab ntxwv daj - 2.5 mg, txiv kab ntxwv daj - 5 mg, paj yeeb - 10 mg, dawb - 20 mg. Tus nqi ntawm Lisinopril yog 70-200 rubles. nyob ntawm qhov ntau npaum li cas thiab cov naj npawb ntawm cov ntsiav tshuaj hauv pob.

Tseem Ceeb! Lisinopril nce lub neej muaj sia nyob ib puag ncig ntawm qhov muaj mob hnyav ntawm lub plawv thiab cov hlab ntshav, nres ventricular kawg tom qab lub plawv nres.

Cov tshuaj sib xyaw ua ke suav nrog lisinopril dihydrate, nyob ntawm qhov chaw tsim khoom ntawm cov ntsiav tshuaj yuav suav nrog ntau cov tshuaj ntxiv uas tsis muaj cov tshuaj kho.

Kev taw qhia rau kev siv:

• kub siab thiab kub siab ntawm ntau yam etiologies,
• myocardial infarction nyob rau hauv mob mob theem,
• mob plawv tsis ua hauj lwm
• kev puas tsuaj rau peripheral poob siab mob los ntawm ntshav qab zib.

Cov tshuaj muaj ntau cov analogues uas muaj kev kho zoo sib xws thiab kev coj ua tsis txawv hauv tus nqi - Lysitar, Vitopril, Dapril, Lipril.

Yuav ua li cas thiaj yuav siv cov tshuaj

Ua ntej pib kev kho mob nrog lisinopril, koj yuav tsum kawm cov lus qhia kom nkag siab tias vim li cas cov tshuaj no pab tau thiab yuav noj li cas. Cov tshuaj tau tawm hauv cov raum, yog li ntawd, muaj cov kab mob loj ntawm cov kabmob no yuav tsum tau qhia rau tus kws kho mob ua ntej pib kho.

Tseem Ceeb! Kev kho kom zoo ntawm cov tshuaj tshwm sim hauv ib teev, qhov kav ntev - tom qab ib hlis kawm. Cov tshuaj ua rau maj mam, yog li nws tsis yog siv los ua kev pabcuam thawj zaug rau kev kub ntxhov.

Lisinopril muaj qhov ua kom ntev, yog li nws txaus noj nws ib hnub ib hnub, nyiam dua thaum sawv ntxov. Haus tshuaj nrog dej kom huv. Qhov tsim nyog kho kom zoo yog tsim los ntawm tus kws kho plawv kom paub txog tus neeg mob lub hnub nyoog thiab nyob ntawm cov kab mob ntev.

Dosage ntawm cov tshuaj nyob ntawm tus kab mob:

1. Mob ntshav qab zib nephropathy - nyob rau theem pib ntawm kev kho mob, tsis pub ntau tshaj 10 mg ntawm cov tshuaj ib hnub twg yuav tsum tau noj. Nws muaj peev xwm nce qhov koob ntxiv rau 20 mg, tab sis qhov no tuaj yeem ua tiav raws li qhov kawg, vim tias qhov muaj qhov tshwm sim muaj ntau qhov tshwm sim hnyav.
2. Kev kub siab, qhov tseem ceeb ntawm kev kub siab - kev kho mob pib nrog ib koob tshuaj 10 mg. Txhawm rau pab txhawb qhov ntsuas qhov ntsuas kom nyob rau hauv qhov qub, koj yuav tsum noj 20 mg tshuaj nyob rau ib hnub. Qhov siab tshaj plaws rau kev nyab xeeb yog 40 mg.
3. Mob plawv tsis ua hauj lwm ntev - kev kho mob pib nrog koob tshuaj 2.5 mg, txhua 3-5 hnub nws tau nce. Qhov tshuaj ntau ntau txhua hnub yog 10 mg.

Thaum kho nrog Lisinopril, nws yog ib qho tsim nyog yuav tsum tau soj ntsuam qhov ntsuas lub siab tas li, kuaj lub raum, thiab rov qab ua ntu zus kom tsis txhob muaj cov kua thiab cov ntsev tsawg. Nws yog ib qho tsim nyog yuav tau ua kom txo qis hauv lub cev, tshwj xeeb hauv huab cua kub.

Kev noj tshuaj ntau dhau tsis tshua muaj tshwm sim - hauv qhov no, ntshav siab poob qis, muaj peev xwm ua rau muaj kev poob siab, qhov kev txhim kho ntawm lub raum tsis ua haujlwm. Thawj qhov kev pabcuam yog pais plab lav, kev qhia ntawm saline.

Tseem Ceeb! Cov tshuaj cuam tshuam kom tsis txhob muaj lub siab xav thiab ua tib zoo saib xyuas, yog li ntawd, nws yog qhov yuav tsum tau txwv tsis pub tsav tsheb, ua kom siab thiab nyob hauv av.

Cov kev thaiv tsis zoo thiab cov tshwm sim

Lisinopril muaj txiaj ntsig pab txoj kev ntshav siab, tab sis cov tshuaj muaj ntau qhov tshwm sim. Yog tias koj ua raws li qhov ntau npaum li cas thiab ua raws nraim li cov tshuaj kho mob kom zoo, tom qab ntawd qhov tsis zoo tshwm sim tom qab noj cov tshuaj tsis pom lossis ploj hauv ob peb hnub.

• mob hauv siab, txo qis hauv cov ntshav siab,
• tsis zoo nyob rau hauv potency,
• mob hauv lub plab zom mov uas ua rau pom qhov tsis xeev siab thiab ntuav,
• nce rau hauv ESR, txo qis hauv hemoglobin qib,
• nce nitrogen cov ntsiab lus ntawm urea thiab keratin,
• mob tej pob txha
• leeg tsis muaj zog, mob taub hau, kiv taub hau.

Nyob rau theem pib ntawm kev kho, kev ua xua nyob rau hauv daim ntawv ntawm daim tawv nqaij yuav tshwm sim, qee zaum Quincke's edema tuaj yeem tshwm sim. Feem ntau, noj tshuaj muaj nrog nrog kev hnoos tsis zoo.

Lub ntsiab contraindications yog ib tug neeg intolerance mus rau lub Cheebtsam ntawm cov tshuaj thiab lactose, hypersensitivity rau cov tshuaj los ntawm cov pab pawg ntawm ACE inhibitors, angioedema, idiopathic edema. Lisinopril yog contraindicated thaum cev xeeb tub txhua lub sijhawm, thiab siv thaum lub sijhawm lactation yog ua tau yog tias kev pub mis rau menyuam noj raug ncua. Tsis muaj ntaub ntawv txaus ntseeg txog kev nyab xeeb ntawm kev siv tshuaj hauv pediatrics, yog li nws tsis raug rau cov neeg muaj hnub nyoog 18 xyoo rov hauv.

Kev ceev faj thiab nyob rau hauv kev saib xyuas tas li ntawm kws kho mob yuav tsum noj lisinopril rau cov neeg laus, cov mob ntshav qab zib, yog tias muaj keeb kwm muaj mob ntsws raum, los yog muaj teeb meem rau cov hlab hlwb.

Peb tuaj yeem hais meej meej txog qhov tsis muaj kev sib haum ntawm Lisinopril thiab cawv. Thaum kho, dej qab zib thiab npaj uas muaj ethanol yuav tsum tshem tawm tag nrho. Cov tshuaj pab txhim kho lub txiaj ntsig tsis zoo ntawm cawv ntawm lub cev, uas tuaj yeem ua rau muaj kev loj hlob ntawm daim siab tsis zoo.

Tseem Ceeb! Ua ntej noj Lisinopril rau qhov siab, nws yog qhov yuav tsum tau soj ntsuam tag nrho kom tshem tawm lub xub ntiag ntawm lub raum pathologies thiab tshem tawm lub cev qhuav dej.

Lisinopril lossis enalapril - uas yog ib qho zoo dua?

Lisinopril zoo txo ​​cov ntshav siab ntau dua, thiab cov txiaj ntsig kho tau ntev dua li ntawm enalapril, uas yuav tsum noj ob zaug ib hnub. Ob qho tshuaj tau pauv kwv yees li qub, tab sis enalapril tsis cuam tshuam loj heev potency thiab raug tawm los ntawm daim siab thiab lub raum.

Diroton lossis Lisinopril - uas yog ib qho zoo dua?

Cov tshuaj muaj ntau yam nyob rau hauv ntau - lawv tau tso tawm rau hauv daim ntawv ntawm cov ntsiav tshuaj nrog qhov ntau npaum ntawm 5-20 mg, nws txaus los noj lawv ib hnub ib zaug, cov nyhuv ntev ntev tau tiav tom qab 2-4 lub lis piam. Tab sis kom tswj hwm kev ua kom zoo, qhov koob tshuaj Diroton yuav tsum yog 2 npaug ntau dua li Lisinopril.

Muaj qee qhov sib txawv ntawm cov contraindications. Diroton yuav tsum tsis txhob coj los ntawm cov neeg uas muaj kev mob caj dab rau Quincke's edema. Lisinopril yog txwv tsis pub noj nrog lactose intolerance. Txwv tsis pub, cov nyhuv ntawm cov tshuaj yog zoo tib yam.

Lisinopril lossis Lozap - uas zoo dua?

Ob qho tshuaj yeeb tshuaj ob leeg koom rau ACE inhibitor pawg, tab sis Lozap yog qhov siv tshuaj kim. Nws yog ntawv sau tsuas yog tus neeg mob tau siv tsis haum rau txhua lwm yam tshuaj siv nyiaj los ntawm pawg no.

Ib qho tshuaj twg uas muaj ntshav siab tuaj yeem noj tsuas yog tom qab sab laj kev kho plawv - txhua yam tshuaj muaj hwj chim muaj ntau yam contraindications thiab phiv. Kev kho tus kheej ntawm kev kub siab tuaj yeem ua rau txo qis hauv qhov ntsuas qis dua qhov tso cai tsawg kawg, tsis nco qab thiab lwm yam kev rau mob hnyav.

Cov yam ntxwv dav dav. Muaj pes tsawg leeg:

Lisinopril 5 mg Yam khoom xyaw: lisinopril dihydrate coj mus rau 5 mg ntawm lisinopril,
Lisinopril 10 mg Cov khoom xyaw dhia: lisinopril dihydrate sib haum rau 10 mg ntawm lisinopril,
Lisinopril 20 mg Cov khoom xyaw dhia: lisinopril dihydrate coj mus rau 20 mg ntawm lisinopril,
Cov muaj mob: cov piam thaj mis (lactose), calcium stearate.

Cov lus piav qhia: Cov ntsiav tshuaj 5 mg thiab 10 mg - dawb lossis yuav luag dawb, tiaj tus-cylindrical, nrog bevel. Cov ntsiav tshuaj 20 mg - dawb lossis yuav luag dawb, tiaj-cylindrical nyob rau hauv cov duab, nrog chamfer thiab kev pheej hmoo.

Cov yam ntxwv Pharmacological:

Cov Tshuaj Hauv Tshuaj ACE inhibitor, txo qhov tsim ntawm angiotensin II los ntawm angiotensin I. Txo cov ntsiab lus ntawm angiotensin II ua rau txo qis ncaj qha rau kev tso tawm aldosterone. Txo cov kev ua haujlwm ntawm bradykinin thiab nce cov synthesis ntawm prostaglandins. Txo tag nrho peripheral vascular tsis kam, ntshav siab (BP), preload, siab nyob rau hauv cov hlab ntsws capillaries, ua rau kev nce ntshav feeb thiab nce myocardial zam rau kev ntxhov siab hauv cov neeg mob uas mob plawv tsis ua haujlwm. Nthuav cov hlab ntsha mus rau qhov ntau dua li cov leeg ntshav. Qee qhov cuam tshuam tau piav qhia los ntawm cov nyhuv rau cov ntaub so ntswg renin-angiotensin. Nrog rau siv ntev, hypertrophy ntawm myocardium thiab phab ntsa ntawm cov hlab ntsha ntawm hom tiv thaiv poob qis. Txhim kho cov ntshav xa mus rau ischemic myocardium.
ACE inhibitors lengthen lub neej nyob ntev hauv cov neeg mob uas muaj lub plawv tsis ua haujlwm ntev, qeeb cov kev vam meej ntawm sab laug ventricular kev ua haujlwm tsis zoo hauv cov neeg mob tom qab myocardial infarction yam tsis muaj kev soj ntsuam lub plawv tsis ua haujlwm. Cov nyhuv antihypertensive pib tom qab li 6 teev thiab kav rau 24 teev. Lub sijhawm ntawm cov nyhuv kuj nyob ntawm qhov koob tshuaj. Qhov pib ntawm kev ua yog tom qab 1 teev. Qhov siab tshaj plaws ua tau txiav txim siab tom qab 6-7 teev. Nrog rau cov hlab ntsha o, cov nyhuv tshwm sim hauv thawj hnub tom qab pib kev kho mob, cov nyhuv ruaj khov tshwm sim tom qab 1-2 lub hlis. Nrog kev tshem tawm sai ntawm cov tshuaj, tsis muaj qhov cim tseg hauv ntshav siab tau pom.
Ntxiv rau qhov txo qis ntshav siab, lisinopril txo cov albuminuria. Hauv cov neeg mob hyperglycemia, nws pab ua kom lub cev ua haujlwm ntawm glomerular endothelium tsis ua haujlwm.
Lisinopril tsis cuam tshuam rau cov ntshav qabzib hauv cov neeg mob ntshav qab zib mellitus thiab tsis ua rau muaj kev nce ntxiv hauv cov neeg mob hypoglycemia.

Cov Tshuaj Pharmacokinetics Kev Ntaus Xuas: Tom qab kev tswj hwm ntawm qhov ncauj, kwv yees li 25% ntawm Lisinopril yog nqus los ntawm txoj hnyuv plab. Noj mov tsis cuam tshuam rau kev nqus ntawm cov tshuaj. Bioavailability yog 29%.
Kev xa Khoom. Yuav luag tsis khi rau cov plasma protein. Qhov siab tshaj plaws ntshav plasma (90 ng / ml) mus txog tom qab 7 teev. Kev tso cai hla ntawm cov ntshav-hlwb thiab thaj chaw teeb meem yog tsawg.
Kev zom zaub mov. Lisinopril tsis muaj biotransformed hauv lub cev.
Chaw Sau Ntawv. Nws yog tawm los ntawm lub raum tsis hloov pauv. Ib nrab-lub neej yog 12 teev.
Pharmacokinetics hauv qee pab pawg ntawm cov neeg mob: Hauv cov neeg mob uas muaj lub plawv tsis ua hauj lwm ntev, kev nqus thiab tshem tawm ntawm Lisinopril txo.
Hauv cov neeg mob uas lub raum tsis ua haujlwm, qhov kev cia siab ntawm Lisinopril yog ntau zaus ntau dua li qhov kev sib txuam hauv cov ntshav ntawm cov neeg ua haujlwm pub dawb, thiab muaj lub sijhawm nce mus txog qhov siab tshaj plaws hauv cov ntshav ntshav thiab nce ntxiv hauv ib nrab ntawm lub neej.
Hauv cov neeg mob laus, cov tshuaj ntawm cov tshuaj nyob rau hauv cov ntshav plasma thiab thaj chaw hauv qab nkhaus yog 2 npaug ntau dua ntawm cov neeg mob hluas.

Kev taw qhia rau kev siv:

- Kev mob ntshav siab (nyob rau hauv monotherapy lossis hauv kev sib xyaw nrog lwm cov tshuaj antihypertensive),
- Kev mob plawv tsis tu ncua (ua ib feem ntawm txoj kev kho ua ke rau kev kho mob ntawm cov neeg mob noj digitalis thiab / lossis diuretics),
- Kev kho thaum ntxov ntawm mob myocardial infarction (hauv thawj 24 teev nrog cov hemodynamics ruaj khov los tswj cov ntsuas no thiab tiv thaiv sab laug ventricular kawg thiab lub plawv tsis ua haujlwm),
- Mob ntshav qab zib nephropathy (txo qis rau albuminuria hauv cov neeg mob ntshav insulin-uas muaj ntshav siab thiab cov neeg mob tsis haum tshuaj muaj kev mob ntshav siab).

Muab thiab kev coj:

Sab hauv, tsis hais txog pluas noj. Nrog rau cov hlab ntsha o, cov neeg mob tsis tau txais lwm cov tshuaj tiv thaiv kev tiv thaiv kabmob 5 yam tshuaj ib hnub ib zaug. Yog tias tsis muaj kev cuam tshuam, qhov koob tshuaj tau nce ntxiv txhua 2-3 hnub los ntawm 5 mg rau qhov nruab nrab cov tshuaj kho 20-40 mg / hnub (nce ntau dua koob dua 40 mg / hnub feem ntau tsis ua rau txo qis ntshav siab).
Cov koob tshuaj saib xyuas txhua hnub li 20 mg. Qhov nyiaj pab ntau tshaj txhua hnub yog 40 mg. Tag nrho cov txiaj ntsig feem ntau tshwm sim tom qab 2-4 lub lis piam los ntawm kev pib kho, uas yuav tsum tau coj mus rau hauv tus account thaum nce qhov koob tshuaj. Nrog cov kab mob tsis txaus ntseeg, nws muaj peev xwm los sib xyaw cov tshuaj nrog lwm cov tshuaj tiv thaiv kabmob.
Yog tias tus neeg mob tau txais kev kho mob ua ntej nrog diuretics, tom qab ntawd qhov kev haus tshuaj ntawm cov tshuaj yuav tsum nres 2-3 hnub ua ntej pib ntawm Lisinopril. Yog tias qhov no ua tsis tau, tom qab ntawd thawj zaug ntawm Lisinopril yuav tsum tsis pub tshaj 5 mg rau ib hnub. Hauv qhov no, tom qab noj thawj koob, kev saib xyuas kev noj qab haus huv raug pom zoo rau ob peb teev (qhov siab tshaj plaws ua tiav tau tom qab kwv yees li 6 teev), txij li pom qhov txo qis hauv ntshav siab tuaj yeem tshwm sim.
Nyob rau hauv kev tshwm sim ntawm kev kho lub plawv tawg lossis lwm yam kev mob nrog kev ua si ntau ntxiv ntawm renin-angiotensin-aldosterone system, nws tseem yuav tsum tau tshaj tawm cov koob tshuaj qis ntawm 2.5-5 mg ib hnub, nyob rau hauv kev saib xyuas kev kho mob (tswj ntshav siab, raum kev ua haujlwm, poov tshuaj concentration hauv cov ntshav). Kev saib xyuas cov koob tshuaj, txuas ntxiv kev tswj hwm kev kho mob nruj, yuav tsum txiav txim siab nyob ntawm qhov kev hloov pauv ntawm cov ntshav siab.
Yog hais tias lub raum tsis ua haujlwm, vim qhov tseeb tias lisinopril raug ntog dhau los ntawm lub raum, thawj koob tshuaj yuav tsum txiav txim siab nyob ntawm qhov kev tshem tawm creatinine, tom qab ntawd, raws li qhov tshuaj tiv thaiv, ib qho kev saib xyuas yuav tsum tau tsim nyob rau hauv cov xwm txheej ntawm kev soj ntsuam ntau zaus ntawm lub raum muaj nuj nqi, cov poov tshuaj, sodium ntshav dej.

Creatinine tshem tawm ml / min Thawj koob tshuaj mg / hnub
30-70 5-10
10-30 2,5-5
tsawg dua 10 2.5
(suav nrog tus neeg mob kho nrog hemodialysis)

Nrog cov kev pheej hmoo ntawm cov hlab ntshav siab, kev kho lub sij hawm ntev ntawm 10-15 mg / hnub yog qhia.
Hauv kev mob plawv tsis ua haujlwm ntev - pib nrog 2.5 mg ib hnub ib zaug, tom qab los ntawm koob tshuaj nce 2.5 mg nyob rau hauv 3-5 hnub rau ib txwm, txhawb kev noj tshuaj txhua hnub ntawm 5-20 mg. Qhov tshuaj yuav tsum tsis pub tshaj 20 mg ib hnub twg.
Hauv cov neeg laus, ib qho kev tshaj tawm ntev-ntev hypotensive nyhuv yog feem ntau pom, uas cuam tshuam nrog kev txo qis ntawm Lisinopril kev tshem tawm (nws raug pom zoo kom pib kho nrog 2.5 mg / hnub).
Mob myocardial infarction (raws li ib feem ntawm txoj kev kho ua ke)
Thawj hnub - 5 mg hais lus, tom qab ntawd 5 mg txhua lwm hnub, 10 mg txhua ob hnub thiab tom qab ntawd 10 mg ib hnub ib zaug. Hauv cov neeg mob uas muaj mob myocardial infarction, cov tshuaj yuav tsum tau siv tsawg kawg 6 lub lis piam.
Thaum pib kho lossis thaum thawj 3 hnub tom qab muaj mob myocardial ntau nyob rau hauv cov neeg mob uas muaj ntshav tsawg systolic (120 hli Hg lossis qis dua), ib koob tshuaj qis dua yuav tsum raug kho - 2.5 mg. Thaum muaj ntshav nce siab (systolic ntshav qis dua lossis sib npaug li 100 mm Hg), qhov koob tshuaj txhua hnub ntawm 5 mg tuaj yeem, yog tias tsim nyog, yuav raug txo qis rau 2.5 mg. Thaum lub cim ntev heev txo cov ntshav siab (systolic ntshav qis dua 90 hli Hg rau ntau dua 1 teev), kev kho mob nrog Lisinopril yuav tsum tsis ua haujlwm ntxiv.
Ntshav qab zib nephropathy.
Hauv cov neeg mob uas tsis mob ntshav qab zib tsis yog insulin, 10 mg ntawm Lisinopril yog siv ib hnub ib zaug.Qhov koob tshuaj yuav yog, yog tias tsim nyog, nce ntxiv rau 20 mg ib hnub ib zaug txhawm rau kom ua tiav diastolic ntshav siab qis dua 75 hli Hg. hauv ib txoj hauj lwm zaum. Hauv cov neeg mob uas muaj ntshav qab zib insulin-tiv thaiv kab mob ntshav qab zib, qhov ntau npaum qhov qub, thiaj li ua tiav diastolic ntshav siab qis dua 90 hli Hg. hauv ib txoj hauj lwm zaum.

Daim Ntawv Thov Nta:

Cov tsos mob hypotension.
Feem ntau, qhov cim tseg ntawm cov ntshav siab tshwm sim nrog qhov txo qis cov dej hauv lub cev los ntawm kev kho diuretic, txo qis ntsev hauv zaub mov, lim ntshav, raws plab, lossis ntuav. Hauv cov neeg mob uas muaj lub plawv mob tsis ua hauj lwm nrog lub raum tsis ua haujlwm zoo los yog tsis muaj nws, qhov cim tseg yuav txo qis ntshav siab yog qhov ua tau. Nws pom ntau nyob hauv cov neeg mob uas muaj mob loj heev ntawm lub plawv tsis ua hauj lwm ntev, vim qhov txiaj ntsig ntawm kev siv cov tshuaj loj ntawm diuretics, hyponatremia, lossis ua rau lub raum tsis ua haujlwm. Hauv cov neeg mob zoo li no, kev kho mob nrog Lisinopril yuav tsum tau pib los ntawm kev saib xyuas ntawm tus kws kho mob (nrog ceev faj, xaiv koob tshuaj thiab tshuaj diuretics).
Cov kev cai zoo ib yam yuav tsum tau ua thaum kho mob rau cov neeg mob plawv, mob ntshav hlab hlwb tsis txaus, uas kev txo cov ntshav siab tuaj yeem ua rau myocardial infarction lossis mob stroke.
Kev hloov pauv hypotensive tsis yog kev sib kis rau kev noj cov tshuaj txuas ntxiv ntawm cov tshuaj.
Thaum siv Lisinopril hauv qee cov neeg mob uas muaj lub plawv tsis ua haujlwm ntev, tab sis nrog ntshav siab lossis ntshav qis, kev txo qis hauv ntshav yuav tshwm sim, uas feem ntau tsis muaj laj thawj rau kev kho mob.
Ua ntej pib txoj kev kho mob nrog Lisinopril, yog tias ua tau, ua kom lub cev tsis zoo ntawm sodium thiab / lossis ua rau kom ploj ntawm cov kua dej, ua tib zoo saib xyuas cov txiaj ntsig ntawm kev siv tshuaj pib ntawm Lisinopril rau ntawm tus neeg mob. Thaum muaj mob rau lub raum mob hlwb (tshwj xeeb tshaj yog nrog ob tog stenosis, lossis nyob rau ntawm qhov pom ntawm lub raum leeg lub raum), zoo li lub plawv mob tsis ua haujlwm vim tsis muaj sodium thiab / los yog kua, kev siv Lisinopril kuj tseem tuaj yeem ua rau lub raum tsis zoo, mob raum tsis ua haujlwm, uas feem ntau Nws hloov tawm tsis ua haujlwm tom qab tsis ua tiav ntawm cov tshuaj.
Hauv cov kab mob myocardial infarction:
Kev siv cov qauv kev kho mob (thrombolytics, acetylsalicylic acid, beta-blockers) yog qhia. Lisinopril tuaj yeem siv rau hauv kev txuas nrog kev tswj hwm los yog nrog kev siv tshuaj kho kab mob ntawm nitroglycerin.
Kev pab cuam phais mob / ua kom loog.
Nrog kev phais mob ntxiv, nrog rau kev siv lwm yam tshuaj uas ua rau txo cov ntshav siab, Lisinopril, thaiv kev tsim cov tshuaj angiotensin II, tuaj yeem ua rau tsis pom tseeb tias yuav txo cov ntshav siab.
Hauv cov neeg mob laus, cov koob tshuaj ib zaug ua rau muaj kev nkag siab ntau dua ntawm cov tshuaj hauv cov ntshav, yog li, tshwj xeeb yuav tsum tau saib xyuas thaum txiav txim qhov koob.
Vim tias qhov teeb meem pheej hmoo ntawm agranulocytosis tsis tuaj yeem tswj hwm tau, yuav tsum muaj kev soj ntsuam cov ntshav saib ntshav ib zaug. Thaum siv cov tshuaj nyob rau hauv lub raws lim ntshav nrog polyacryl-nitrile membrane, anaphylactic kev poob siab tuaj yeem tshwm sim, yog li ntawd, nws raug nquahu tias ib yam txawv ntawm daim nyias nyias rau kev lim ntshav, lossis kev teem sijhawm ntawm lwm tus neeg sawv cev antihypertensive.
Cuam tshuam rau kev muaj peev xwm tsav tsheb thiab tshuab.
Tsis muaj cov ntaub ntawv hais txog qhov zoo ntawm Lisinopril ntawm kev muaj peev xwm tsav lub tsheb thiab cov txheej txheem siv hauv kev siv tshuaj, tab sis nws yuav tsum tau yug los rau hauv lub siab tias kiv taub hau yog ua tau, yog li ceev faj yuav tsum siv.

Phiv los sis:

Cov kev mob tshwm sim feem ntau: kiv taub hau, mob taub hau, qaug zog, zawv plab, hnoos qhuav, xeev siab.
- Los ntawm cov hlab plawv system: cim txo qis hauv cov ntshav siab, mob hauv siab, tsis tshua muaj - orthostatic hypotension, tachycardia, bradycardia, cov kev mob tshwm sim ntawm lub plawv tsis ua haujlwm, tsis hnov ​​qab ntawm lub plawv atrioventricular conduction, myocardial infarction, plawv palpitations.
- Los ntawm lub hauv nruab nrab hauv lub paj hlwb: mus ob peb vas lab, tsis meej pem, paresthesia, nkees nkees, tawv nqaij ntawm lub cev ntawm nqaj thiab daim di ncauj, tsis tshua muaj - asthenic syndrome.
- Los ntawm cov kab mob hemopoietic: leukopenia, neutropenia, agranulocytosis, thrombocytopenia, ntshav liab (txo ntshav hauv hemoglobin, hematocrit, erythrocytopenia).
- Kev ntsuas ntsuas: hyperkalemia, hyponatremia, tsis tshua muaj - nce kev ua si ntawm "daim siab" enzymes, hyperbilirubinemia, nce qib ntawm urea thiab creatinine.
- Los ntawm cov txheej txheem ua pa: dyspnea, bronchospasm.
- Los ntawm cov mob plab zom mov: qhov ncauj qhuav, tsis nco qab, mob plab ua hauj lwm, hloov pauv, mob plab, mob caj pas, kab mob, mob rau daim tawv nqaij los yog cholestatic daj ntseg, kab mob siab.
- Los ntawm daim tawv nqaij: urticaria, nce hws, khaus, alopecia, photosensitivity.
- Los ntawm cov kab mob genitourinary: ua rau lub raum tsis ua haujlwm, oliguria, anuria, mob raum tsis zoo, uremia, proteinuria, txo qis potency. Ua xua: kev npau taws rau lub ntsej muag, tes taw, ob daim di ncauj, tus nplaig, epiglottis thiab / lossis lub qhov ntsej muag, ua pob rau daim tawv nqaij, khaus, ua npaws, muaj cov tshuaj tiv thaiv kab mob txhaj tshuaj tiv thaiv kab mob, nce erythrocyte sedimentation tus nqi (ESR), eosinophilia, leukocytosis. Hauv qee qhov tsis tshua muaj tshwm sim, interstitial angioedema.
- Lwm yam: myalgia, mob caj dab / mob caj dab, mob vasculitis.

Kev cuam tshuam nrog lwm cov tshuaj:

Lisinopril txo qis excretion ntawm poov tshuaj los ntawm lub cev thaum kho nrog diuretics. Yuav tsum tau ceev faj tshwj xeeb thaum siv cov tshuaj nrog: potassium-sparing diuretics (spironolactone, triamteren, amiloride), potassium, sodium chloride hloov pauv muaj cov potassium (qhov kev pheej hmoo ntawm kev txhim kho hyperkalemia nce, tshwj xeeb nrog kev ua haujlwm tsis zoo hauv lub raum), yog li lawv tuaj yeem kho ua ke tsuas yog lub hauv paus ntawm ib qho kev daws teeb meem cov kws kho mob koom nrog saib xyuas cov poov tshuaj ntau ntau thiab lub raum ua haujlwm.
Ceev faj yuav siv tau ua ke:
- nrog rau diuretics: nrog rau kev tswj hwm ntxiv ntawm ib lub diuretic rau tus neeg mob noj Lisinopril, raws li txoj cai, ib qho kev tiv thaiv kev tiv thaiv kab mob ntxiv tshwm sim - txoj kev pheej hmoo ntawm lub suab txo qis hauv cov ntshav siab,
- nrog rau lwm cov tshuaj tiv thaiv kabmob (ntxiv cov nyhuv ntxiv),
- nrog rau cov tshuaj tsis-steroidal anti-inflammatory (indomethacin, thiab lwm yam), estrogens, ntxiv rau adrenostimulants - ib qho kev txo qis ntawm cov nyhuv ntawm Lisinopril,
- nrog cov roj ntsha lithium (kev tso tawm cov roj ntsha lithium tuaj yeem txo qis, yog li ntawd, cov roj ntsha lithium concentration yuav tsum tau soj ntsuam tas li),
- nrog antacids thiab colestyramine - txo kev nqus ntawm txoj hnyuv plab. Cawv ua kom qhov zoo ntawm cov tshuaj.

Cov Tshuaj Tiv Thaiv:

Cov tshuaj tiv thaiv tsis haum rau Lisinopril lossis lwm yam ACE inhibitors, keeb kwm ntawm kev mob hlwb, suav nrog kev siv ACE inhibitors, kev tiv thaiv kab mob Quincke edema, hnub nyoog qis dua 18 xyoo (qhov ua tau zoo thiab kev nyab xeeb tsis tau tsim).

Nrog ceev faj: kev mob raum tsis zoo, ob tog raum mob leeg lub plawv los yog qog ntshav ntawm lub raum tib leeg nrog kev mob azotemia, lub raum tsis ua haujlwm, lub raum tsis ua haujlwm, azotemia, hyperkalemia, stenosis ntawm aortic orifice, hypertrophic obstructive cardiomyopathy, thawj hyperaldrosis, mob ntshav siab, suav nrog cerebrovascular tsis txaus), mob plawv, mob tsis txaus rau lub plawv, mob ua tsis muaj kabmob cov kab mob tiv thaiv cov nqaij mob (suav nrog scleroderma, cov kab mob lupus erythematosus), kev txwv tsis pub cov pob txha txha ntshav, kev noj zaub mov nrog sodium txwv: kev mob hypovolemic (suav nrog los ntawm kev mob plab, ntuav), lub hnub nyoog laus.
Siv thaum cev xeeb tub thiab lactation. Daim ntawv thov: Lisinopril thaum cev xeeb tub yog contraindicated. Thaum xeeb tub yog tsim muaj, cov tshuaj yuav tsum tau txiav kom sai li sai tau. Kev lees txais ntawm ACE inhibitors nyob rau xyoo II thiab III ntawm lub sijhawm cev xeeb tub muaj qhov tsis zoo ntawm cov menyuam hauv plab (lub suab txo qis hauv cov ntshav siab, lub raum tsis ua haujlwm, hyperkalemia, pob txha taub hau hypoplasia, kev mob plab tuag yog qhov ua tau). Tsis muaj cov ntaub ntawv qhia txog cov tshuaj tsis zoo ntawm cov tshuaj ntawm tus me nyuam yog siv thaum thawj thawj lub hlis. Rau cov menyuam mos thiab cov menyuam mos uas muaj kev kis mob rau ACE inhibitors, nws raug nquahu kom ua tib zoo saib xyuas kom ncav sijhawm kom paub tseeb tias yuav txo cov ntshav siab, oliguria, hyperkalemia.
Lisinopril hla lub tsho me me. Tsis muaj ntaub ntawv qhia txog kev nkag mus ntawm lisinopril rau hauv niam mis. Rau lub sijhawm ntawm kev kho mob nrog tshuaj, nws yog ib qho tsim nyog kom thim tsis pub niam mis.

Noj ntau dhau

Cov tsos mob (tshwm sim thaum noj ib koob tshuaj 50 mg lossis siab dua): qhov cim nce siab hauv cov ntshav siab, qhov ncauj qhuav, tsaug zog, tso zis, tso quav, cem quav, ntxhov siab, nce siab. Kev Kho Mob: cov tsos mob kho, kev tswj dej ua kom dej, tswj ntshav siab, dej-electrolyte tshuav nyiaj li cas thiab ua haujlwm rau tom kawg.
Lisinopril tuaj yeem tshem tawm ntawm lub cev los ntawm hemodialysis.

Cov sijhawm so:

5, 10 lossis 20 mg ntsiav tshuaj. 10 ntsiav tshuaj rau ib lub hlwv ntim los ntawm ib zaj duab xis ntawm polyvinyl chloride thiab aluminium ntawv ci, 20 lossis 30 ntsiav tshuaj rau ib lub khob ntawm lub teeb-ntawv pov thawj lossis lub poom tshuaj polymer lossis lub raj mis polymer, txhua tus tuaj yeem lossis lub raj mis lossis 1, 2 lossis 3 blister ntim nrog cov lus qhia rau kev siv muab ntim rau hauv cov thawv ntawv los qhia.