Diabetalong, Lavxias analogues ntawm cov tshuaj nrog cov nqi thiab tshuaj xyuas

Diabetalong yog ib qho tshuaj siv rau hauv lub cev uas tau siv ua ib feem ntawm kev kho mob ntshav siab los yog ua ke nrog kev kho mob ntshav qab zib hom 2. Ntshav qab zib cov ntsiav tshuaj tau sau tseg rau hauv qhov tsis muaj qhov tseem ceeb ntawm kev hloov kho khoom noj thiab kev siv lub cev ntawm tus neeg mob, sib haum rau nws lub hnub nyoog thiab lub cev yam ntxwv.

Kev kho mob nrog cov tshuaj yuav tsum tau ua ke nrog kev kho kom zoo rau lub cev (cov lus 9) - qhov no tsim nyog los tiv thaiv hypoglycemic tawm tsam thiab nce kev ua haujlwm ntawm kev kho mob.

Cov yam ntxwv txawv ntawm cov tshuaj yog lub caij nyoog tso tawm ntawm cov tshuaj nquag, uas tso cai rau txo qis cov tshuaj txhua hnub thiab ua kom muaj kev sib txig sib luag ntawm cov piam thaj hauv ib chav ntawm cov ntshav.

Thov

"Diabetalong" yog hais txog ib pawg tshuaj uas muaj cov nyhuv hypoglycemic, uas yog siv los ua kev kho mob tseem ceeb rau qhov tsis yog-insulin-mob ntshav qab zib mellitus. Cov tshuaj ua haujlwm nquag ntawm cov ntsiav tshuaj yog gliclazide.

Qhov no yog ib qho yeeb tshuaj nrog cov haujlwm siab xaiv, nrog rau bioavailability thiab nce tsis kam mus rau ntau qhov chaw ib puag ncig.

Kev kho qhov ua haujlwm ntawm cov tshuaj yog vim muaj cov yam ntxwv ntawm gliclazide, cov uas:

nce zais cia ntawm lawv tus kheej cov insulin, uas txo cov koob tshuaj hormone tso rau hauv cov ntshav,
kev txhawb nqa ntawm cov kev ua ntawm beta hlwb (cov hlwb uas ua cov ntaub so ntswg thiab paub meej tias nws cov khoom endocrine),
normalization ntawm carbohydrate metabolism (tshwj xeeb tshaj yog nyob rau cov neeg mob rog rog ntshav qab zib hom 2, 3 lossis 4 degrees),
kev txwv tsis pub platelet aggregation (fusion) thiab kev tiv thaiv ntawm thrombocytopenia, thromboembolism thiab thrombosis.

Nws yog qhov tseeb tias Diabetalong muaj cov kev ua haujlwm antisclerotic thiab txo qis kev pheej hmoo ntawm kev tsim cov kev mob phom sij los ntawm lub siab, cov hlab ntsha, plab hnyuv plab thiab lub hlwb.

Cov tshuaj ua haujlwm nquag ntawm cov tshuaj muaj lub sijhawm ntev tso, thiab nws cov kev xav ntau tshaj yog tau hauv 4-6 teev.

Cov nyhuv ntawm cov tshuaj yog cia rau 10-12 teev, thiab ib nrab lub neej yog txij li 6 txog 12 teev (nyob ntawm kev ua haujlwm ntawm lub raum).

Kev taw qhia rau cov tshuaj yog hom 2 mob ntshav qab zib mellitus - ib hom tshuaj insulin-ywj siab uas tus neeg mob txhim kho mob hyperglycemia (qhov ntshav nce ntxiv nyob hauv ntshav) thiab cov ntaub so ntswg rhiab rau insulin tsis muaj zog.

Daim ntawv tso tawm

"Diabetalong" muaj nyob hauv ib daim ntawv ntau npaum - ncua ntxiv-hloov lossis hloov-tso cov ntsiav tshuaj. Lub tsev lag luam kws tsim tshuaj tsim ob lub tshuaj:

30 mg (ntim ntawm 30 daim) - pom zoo rau thawj theem ntawm kev kho mob,
60 mg (ntim ntawm 60 daim).

Cov chaw tsim khoom siv cov khoom sib ntxiv raws li cov khoom siv ntu, piv txwv, calcium stearate, silicon dioxide thiab talc.

Kev tsis haum rau cov tshuaj tuaj yeem tshwm sim los ntawm lactose (hauv daim ntawv ntawm monohydrate) - cov roj ntsha ntawm cov mis nyuj muaj suab thaj nrog cov dej txuas nrog.

Cov neeg mob uas muaj cov mob ua tsis taus mis los yog muaj lactase tuaj yeem ua rau mob plab tsis ua hauj lwm, yog li ntawd, nrog cov kab mob no, cov khoom hloov kho lossis hloov pauv nrog cov khoom zoo sib xws uas tsis muaj cov piam thaj mis yuav tsum xaiv.

Cov ntsiav tshuaj yog xim dawb thiab ca hauv daim duab zoo li tus kheej kheej.

Qee qhov xwm txheej, cov tshuaj yuav muaj lub plhaw tws - qhov tshwm sim no tau piav qhia los ntawm kev faib tawm tsis ncaj ntawm talcum hauv paus thiab tsis cuam tshuam rau lub zog ntawm cov tshuaj.

Cov lus qhia rau kev siv

Cov lus qhia rau kev siv "Diabetalong" pom zoo kom noj cov tshuaj 1 rau 2 zaug hauv ib hnub (nyob ntawm seb siv tshuaj npaum li cas).

Yog tias qhov tshuaj txhua hnub ntawm cov tshuaj yog 1-2 ntsiav tshuaj, lawv yuav tsum noj ib lub sijhawm thaum sawv ntxov.

Dua li ntawm qhov tseeb tias cov lus xaiv tso cai noj cov ntsiav tshuaj thaum noj mov, cov kev kho mob yuav zoo dua yog tias koj noj "Diabetalong" 10-20 feeb ua ntej noj mov.

Yog hais tias tus neeg mob tsis nco qab noj tshuaj, nws yog ib qho tsim nyog yuav tau rov ua kev kho mob los ntawm daim ntawv thov tom ntej tau muab rau los ntawm cov kws kho mob tau siv thiab muab ntau npaum li cas.

Tsis txhob nce lub koob tshuaj (piv txwv li, koj tsis tuaj yeem noj tsis pom kev noj tshuaj thaum sawv ntxov nyob rau yav tsaus ntuj), vim tias qhov no tuaj yeem ua rau muaj kev pheej hmoo rau cov ntshav qog ntshav qab zib thiab kev loj hlob ntawm lub cev tsis xeev, tshwj xeeb tshaj yog nyob rau cov neeg tshaj 65 thiab cov neeg mob uas muaj kev pheej hmoo.

Cov Yuav Tsum Muaj

Ua ntej noj ib qho tshuaj hypoglycemic, koj yuav tsum sab laj nrog tus kws kho mob, thiab tawm tsam keeb kwm ntawm kev kho, nws yog qhov tsim nyog los tswj qib qab zib thiab kev ua haujlwm ntawm lub raum.

Nws yog txwv tsis pub noj tshuaj rau hauv pab pawg no rau cov ntshav qab zib hom 1, vim tias qhov no tuaj yeem ua rau ntau cov kev txuam nrog insulin hauv cov ntaub so ntswg.

Glyclazide-based khoom lag luam yog contraindicated rau cov poj niam cev xeeb tub thiab cov niam laus, vim tias lawv tuaj yeem ua rau cov kab mob endocrine loj thiab mob plawv tsis zoo hauv plab thiab menyuam mos.

Lwm yam contraindications rau muab tshuaj Diabetalong muaj xws li:

cov kab mob loj ntawm lub raum thiab mob siab, ua rau ua tiav lossis ib feem ntawm kev ua haujlwm ntawm lub cev,
muaj tej yam mob tshwm sim los ntawm kev ua txhaum ntawm cov metabolism hauv carbohydrate,
tsau cov tshuaj tiv thaiv tsis kam lees lossis qhov mob tsis haum rau cov tshuaj los ntawm cov pab pawg ntawm sulfonylurea derivatives lossis sulfonamides,
mob ntshav qab zib coma thiab nws cov mob uas ntej,
tsis muaj peev xwm ntawm cov enzymes uas zom cov piam thaj hauv cov mis nyuj (vim muaj lactose hauv qhov muaj pes tsawg leeg).

Diabetalong yog npaj rau kev kho mob ntawm cov neeg laus laus xwb.

Rau cov neeg muaj hnub nyoog 65 xyoos, cov tshuaj yuav tau raug tsuas yog yuav tsum tau soj qab xyuas tas li ntawm cov kab mob biochemical ntawm cov ntshav thiab zis, ntxiv rau kev tsim kom muaj kev ntshiab huv. Thaum sau tshuaj, kev noj ntau npaum li cas ntawm cov tshuaj uas siv yuav tsum raug xam tias yog. Nws raug txwv tsis pub noj cov tshuaj gliclazide nrog cov tshuaj tiv thaiv kabmob system raws li miconazole, nrog rau Danazol thiab Phenylbutazone.

Nws yog ib qho tsim nyog yuav tsum pib kho nrog qhov tsawg kawg noj ntawm 30 mg (hloov kho tawm ntsiav tshuaj). Nyob rau tib lub sij hawm tshuaj, nws raug nquahu kom cov neeg muaj kev pheej hmoo rau kev txhim kho hypoglycemic tej yam kev mob. Qhov pheej hmoo txaus ntshai muaj xws li:

kev noj zaub mov tsis txaus nrog cov zaub mov tsis txaus thiab cov vitamins thiab ib qho khoom noj ntau nyob hauv cov khoom noj uas muaj cov carbohydrates thiab cov suab thaj yooj yim,
hnub nyoog laus (tshaj 65)
qhov tsis muaj keeb kwm ntawm kab mob ntawm kev kho mob nrog kev siv tshuaj uas txo cov ntshav qab zib,
kev ntxhov siab nyob hauv kev ua haujlwm ntawm lub qog adrenal thiab lub qog pituitary,
Kev tsim tawm tsis txaus cov thyroid hormones txaus ua rau cov thyroid caj pas,
carotid arteriosclerosis,
mob plawv heev (suav nrog mob plawv 3 thiab 4 degrees).

Cov tshuaj hauv qhov ntau npaum li cas ntawm 30 mg yog noj ib hnub ib zaug thaum sawv ntxov ua ntej lossis thaum noj tshais.

Txog lwm pawg ntawm cov neeg mob, txoj kev muab tshuaj yog xam ntawm tus kheej coj mus rau hauv qhov hnyav ntawm tus kab mob, tus neeg mob lub hnub nyoog, ntshav qab zib thiab lwm yam kev ntsuas ntawm kev kuaj ntshav thiab tso ntshav.

Kev noj tshuaj txhua hnub yuav tsum tsis pub ntau dua 120 mg (2 ntsiav tshuaj ntawm 60 mg lossis 4 ntsiav tshuaj ntawm 30 mg).

Sab sij huam

Cov yam ntxwv tshwm sim cuam tshuam nrog Diabetalong yog mob taub hau, tsis hnov qab, ua rau lub cev tsis muaj ntshav, thiab ua xua rau daim tawv nqaij ua pob. Tsawg tsawg dua, muaj ntawv tshaj tawm lwm cov kev cuam tshuam, uas suav nrog:

kiv taub hau
mob huam
trembling hauv lub cev
hnov tsis hnov qab txiav txim siab,
ua pa nyuaj thiab ua tsis taus nqos muaj nuj nqi,
daj ntawm daim tawv nqaij thiab cov qog ua kua ntawm lub qhov muag sclera (mob siab ntawm cholestatic yam),
txo nyob rau hauv kev pom tseeb tseeb,
nce ntshav siab.

Muaj qee kis, noj cov tshuaj "Diabetalong" tuaj yeem ua rau muaj kev ua txhaum loj hauv daim siab, hem tus neeg mob lub neej. Cov tshuaj kuj tuaj yeem cuam tshuam tsis zoo rau kev ua haujlwm ntawm hematopoiesis ntawm cov pob txha pob txha, yog li ntawd, nws yuav tsum ua raws li kev saib xyuas ntawm tus kws tshaj lij, ua ke nrog kev kho mob kom zoo thiab ua kom lub cev muaj zog.

Tus nqi ntawm "Diabetalong" yog suav hais tias pheej yig rau txhua pawg ntawm cov neeg mob, vim tias cov tshuaj ntawm tus nqi hais txog tus nqi qis dua. Tus nqi nruab nrab rau pob ntawm 60 ntsiav tshuaj yog 120 rubles.

Kev suav tshuaj ntawm cov tshuaj tuaj yeem xav tau yog tias muaj kev tsis haum tshuaj lossis tsis haum rau ib qho twg ntawm cov tshuaj. Txhawm rau tswj cov qib ntawm cov piam thaj, tus kws kho mob tuaj yeem sau cov nyiaj los ntawm pawg pab pawg ntawm sulfonylurea derivatives los yog lwm cov tshuaj ntshav hypoglycemic nrog cov nyhuv tshuaj zoo sib xws.

"Mob ntshav qab zib" (290-320 rubles). Cov nqaj ua piv txwv ntawm "Diabetalong" nrog tib yam khoom muaj nqis. Cov tshuaj yog txiav txim siab zoo dua vim yog pib ntawm kev kho mob sai - qhov siab tshaj plaws ntawm gliclazide ua tiav hauv cov ntshav plasma tsis pub dhau 2-5 teev.
"Gliclazide" (100-120 rubles). Kev npaj hypoglycemic nyob rau hauv daim ntawv ntawm hmoov, ib yam ntxwv analogue ntawm Diabetalong.
"Glucophage ntev" (170-210 rubles). Tshuaj siv sijhawm ntev, uas suav nrog metformin. Nws tuaj yeem siv cov tshuaj tseem ceeb thiab ua ke nrog cov tshuaj insulin thiab lwm yam tshuaj los txo cov suab thaj.

Nws yog tsis yooj yim sua kom tshem tawm cov tshuaj nrog hypoglycemic thaj chaw ntawm lawv tus kheej, txij li lawv xav kom maj mam tshem tawm nrog cov kev txiav txim siab niaj hnub txo thiab kev saib xyuas tsis tu ncua ntawm cov ntshav thiab zis biochemical. Txhua yam tshuaj nyob rau hauv pab pawg no tuaj yeem xaiv thiab tsim cov kws kho mob tshwj xeeb nkaus xwb.

Noj ntau dhau

Yog tias koj ua yuam kev ntau tshaj qhov kev pom zoo thiab qhov pib ntawm cov tsos mob ntawm tus mob hypoglycemic, koj yuav tsum tso cov tshuaj qabzib (40% - 40-80 ml), thiab tom qab ntawd hno cov ntshav qabzib 5-10% nrog ib qho infusate. Nrog cov tsos mob me, koj tuaj yeem nce qib qab zib sai nrog cov khoom uas muaj sucrose lossis carbohydrates yooj yim.

Kev tshuaj xyuas txog cov tshuaj rau cov neeg mob ntshav qab zib "Diabetalong" feem ntau yog qhov zoo.

Tus neeg siv Venera87 los ntawm lub nroog Kursk hauv kev tshuaj xyuas http://otzovik.com/review_3106314.html hais tias cov cuab yeej pab nws cov txheeb ze laus tswj lawv cov suab thaj. Cov tshuaj tau sau tawm hauv cov tshuaj ntawm 30 mg ib hnub ib zaug thiab tau noj nruj me ntsis raws li kws kho mob tau hais. Tsis muaj kev cuam tshuam tshwm sim thaum kho.

Vitaly Koval tseem hais lus zoo txog cov tshuaj thiab hais tias cov ntsiav tshuaj tau pab nws pog nrog tu qab zib ntxiv mus (https://health.mail.ru/drug/diabetalong/).

Tab sis Ivan, ntawm qhov tsis sib thooj, hais tias cov tshuaj tsis haum rau nws txiv, thiab tawm tsam keeb kwm ntawm kev kho mob, tus neeg mob tau pib mob hnyav rau hauv thaj chaw mob plab, vim tias qhov kev kho mob yuav tsum tau nres 10 hnub tom qab pib noj cov ntsiav tshuaj (http: //www.imho24 .ru / kev pom zoo / 57004 / # tshuaj xyuas77231).

"Diabetalong" - cov tshuaj uas yuav tsum yog kws kho mob muab los ntawm kws kho mob nrog rau tus kheej muab xam ntawm qhov ntau thiab kev noj tshuaj. Yog tias cov tshuaj tsis haum nrog tus neeg mob tshwj xeeb, koj yuav tsum sab laj nrog tus kws kho mob thiab xaiv cov tshuaj tsis haum qog ntau.

Txuag lossis sib qhia:

Diabetalong hauv Moscow

Kev siv tshuaj qhov ncauj hypoglycemic, ib qho sulfonylurea derivative ntawm lub cim thib ob.

Nws ua rau lub cev muaj zog ntawm cov insulin los ntawm tus txiav, qis dua qib ntawm cov piam thaj hauv cov ntshav, ua rau cov insulin-secretory zoo li ntawm cov piam thaj thiab ua rau kev nkag siab ntawm cov ntaub so ntswg mus rau insulin. Tom qab 2 xyoos ntawm kev kho mob, feem ntau cov neeg mob tsis txhim kho kev quav yeeb tshuaj (kev nce qib ntawm cov tshuaj inspace tom qab thiab kev zais ntawm C-peptides txuas ntxiv).

Txo lub sijhawm ua ntu zus los ntawm lub sijhawm noj mov kom pib lub insulin secretion.

Nws rov qab pib lub ncov thaum ntxov ntawm insulin secretion hauv kev teb rau cov piam thaj (tsis zoo li lwm yam sulfonylurea derivatives, uas muaj qhov cuam tshuam tshwj xeeb tshaj yog nyob rau theem thib ob ntawm kev zais cia).

Nws tseem ua kom zoo dua theem thib ob ntawm kev tsim cov tshuaj insulin. Txo cov ncov ntawm hyperglycemia tom qab noj mov (txo qis postprandial hyperglycemia).

Glyclazide ntau ntxiv qhov rhiab ntawm peripheral cov ntaub so ntswg rau insulin (i.e., muaj cov lus hais ntxiv ua kom zoo ntxiv). Hauv cov leeg nqaij, cov nyhuv ntawm cov tshuaj insulin rau ntawm cov piam thaj, vim muaj cov ntaub so ntswg hloov pauv mus rau insulin, tau nce ntau (nce txog + 35%), txij li glycazide stimulates cov kev ua ntawm cov leeg glycogen synthetase.

Txo kev tsim cov piam thaj hauv lub siab, ua haujlwm li qub ceev ceev cov piam thaj.

Ntxiv rau kev cuam tshuam rau cov metabolism hauv cov metabolism, gliclazide txhim kho microcirculation.

Cov tshuaj txo txoj kev pheej hmoo ntawm cov hlab ntsha me me, cuam tshuam rau ob lub tswv yim uas yuav koom nrog kev txhim kho cov teeb meem hauv cov ntshav qab zib mellitus: ib feem ntawm kev txwv tsis pub platelet thiab kev sib dhos thiab ib qho kev txo qis hauv kev ua kom muaj platelet ua kom muaj lwm yam (beta-thromboglobulin, thromboxane B2), nrog rau kev kho rov qab ntawm fibrinolytic vascular endothelial kev ua si thiab nce kev ua si ntawm cov nqaij mos plasminogen activator.

Glyclazide muaj cov khoom ua antioxidant: nws txo cov ntshav lipid peroxides hauv ntshav, nce qhov kev ua haujlwm ntawm cov ntshav liab ntshav superoxide dismutase.

Vim tias cov yam ntxwv ntawm daim ntawv muab tshuaj, cov tshuaj txhua hnub ntawm Diabetalong® 30 mg ntsiav tshuaj muab cov tshuaj kho zoo ntawm gliclazide hauv cov ntshav ntshav 24 teev.

Tom qab kev tswj hwm ntawm qhov ncauj, gliclazide yog kiag li nqus los ntawm cov hnyuv. Kev noj tsis cuam tshuam rau kev nqus.

Qhov kev kub siab ntawm cov tshuaj nquag hauv cov ntshav plasma nce ntau zuj zus, nce mus txog qhov siab thiab nce mus txog toj siab 6-12 teev tom qab noj cov tshuaj. Kev hloov pauv ntawm tus kheej muaj feem tsawg.

Cov kev sib raug zoo ntawm cov koob tshuaj thiab kev saib xyuas ntawm cov tshuaj hauv ntshav ntshav yog txoj kab tso siab raws lub sijhawm.

Kev faib khoom thiab cov metabolism

Plasma protein khi yog kwv yees li 95%.

Nws yog metabolized hauv daim siab thiab feem ntau yog tawm los ntawm lub raum. Tsis muaj cov metabolites hauv lub plasma ntshav.

Kev zam los ntawm ob lub raum yog ua tiav rau feem ntau ntawm kev tsim cov tshuaj metabolites, tsawg dua 1% ntawm cov tshuaj yog tawm tsis pauv.

T1 / 2 yog kwv yees li 16 teev (12 txog 20 teev).

Pharmacokinetics hauv cov chaw kuaj mob tshwj xeeb

Hauv cov neeg laus, tsis muaj qhov tshwj xeeb hauv kev kho mob hauv qhov kev hloov pharmacokinetic.

- Hom 2 mob ntshav qab zib mellitus ua ke nrog kev kho kev noj haus nrog kev noj zaub mov tsis txaus thiab kev tawm dag zog.

Cov tshuaj yog npaj rau kev kho mob nkaus xwb. ntawm cov neeg laus.

Diabetalong® 30 mg hloov kho-ntsiav tshuaj noj noj ntawm ncauj 1 lub sijhawm / hnub thaum noj tshais.

Rau cov neeg mob uas tsis tau txais kev kho yav tas los (suav nrog rau cov neeg tshaj 65 xyoo),, qhov kev siv tshuaj pib yog 30 mg. Tom qab ntawd cov koob tshuaj tau xaiv ib tus zuj zus kom txog thaum qhov txiaj ntsig kho tau tiav.

Kev xaiv koob tshuaj yuav tsum tau ua tiav raws li theem ntawm cov piam thaj hauv cov ntshav tom qab pib kev kho mob. Txhua qhov hloov pauv koob tshuaj tom ntej tuaj yeem tau ua tom qab tsawg kawg ob lub lim tiam.

Qhov kev noj tshuaj txhua hnub tuaj yeem hloov los ntawm 30 mg (1 tab.) Txog 90-120 mg (3-4 tab.). Qhov koob tshuaj txhua hnub yuav tsum tsis pub ntau tshaj 120 mg (4 ntsiav tshuaj).

Diabetalong ® tuaj yeem hloov cov tshuaj gliclazide qis dua li niaj hnub (80 mg) hauv 1 txog 4 ntsiav tshuaj / hnub.

Yog tias koj plam ib lossis ntau dua ntawm cov tshuaj, koj tsis tuaj yeem noj ntau dua ntawm qhov koob tshuaj ntxiv (hnub tom qab).

Thaum hloov lwm cov tshuaj hypoglycemic nrog Diabetalong® 30 mg ntsiav tshuaj, tsis muaj lub sijhawm hloov pauv ntawm lub sijhawm. Koj yuav tsum xub tsum tsis txhob noj cov tshuaj ntawm txhua hnub thiab tsuas yog hnub tom qab pib noj cov tshuaj no.

Yog tias tus neeg mob tau txais kev kho mob yav dhau los nrog sulfonylureas nrog ntev dua ib nrab-lub neej, tom qab ntawd ceev faj saib xyuas (saib xyuas ntshav qabzib) rau 1-2 lub lis piam yog qhov tsim nyog kom tsis txhob mob ntshav qab zib ua qhov tsis muaj txiaj ntsig ntawm qhov seem ntawm cov kev kho mob dhau los.

Diabetalong ® tuaj yeem siv nrog kev sib xyaw nrog loj loj, alpha glucosidase inhibitors lossis insulin.

Cov neeg mob uas mob mentsis mus txog rau lub raum tsis ua haujlwm cov tshuaj yog sau rau hauv cov koob tshuaj tib yam li rau cov neeg mob uas lub raum tsis ua haujlwm. Ntawm mob raum tsis ua haujlwm Diabetalong® yog contraindicated.

Hauv cov neeg mob uas muaj kev pheej hmoo txhim kho hypoglycemia (kev noj zaub mov tsis txaus lossis tsis txaus noj, cov mob hnyav lossis cov neeg ua haujlwm tsis txaus ua rau cov leeg endocrine - pituitary thiab adrenal tsis txaus, hypothyroidism, tshem tawm cov glucocorticosteroids tom qab siv sijhawm ntev thiab / lossis kev tswj hwm siab ntau ntxiv), cov kab mob hnyav ntawm cov hlab plawv / kev mob ntshav siab hauv lub plawv, mob hnyav carotid arteriosclerosis, mob atherosclerosis /) nws raug nquahu kom siv cov koob tshuaj tsawg kawg (30 mg 1 teev / hnub) ntawm cov tshuaj Diabetalong®.

Kev Hypoglycemia (ua txhaum rau kev noj tshuaj thiab noj zaub mov tsis txaus): mob taub hau, qaug zog, tshaib plab, tawm hws, mob tsis muaj zog, ua rau lub cev, tsis tuaj yeem, ua kom ntshav nce siab, tsaug zog, pw tsaug zog, ntxhov siab, ntxhov siab, chim siab, tsis tuaj yeem cuam tshuam, tsis tuaj yeem muaj peev xwm mloog thiab qeeb, tsis pom kev, tsis pom kev, tsis pom kev zoo , tshee tshee, paresis, hnov qhov txawv ntawm qhov muag, kiv taub hau, zoo li tsis paub pab, tswj tus kheej, ua kom zoo nkauj, mob plab, ntsaws qhov ncauj, ua pa nyuaj, tsis nco qab, tsis nco qab lawm.

Los ntawm lub plab zom mov: xeev siab, ntuav, raws plab, mob plab, cem quav (qhov mob hnyav ntawm cov tsos mob no tsawg dua thaum noj nrog zaub mov), tsis tshua muaj - lub siab ua haujlwm tsis zoo (mob siab, muaj kev ua haujlwm ntau ntawm hepatic transaminases, alkaline phosphatase, cholestatic jaundice - yuav tsum tshem tawm tshuaj).

Los ntawm cov kabmob hemopoietic: inhibition ntawm cov pob txha mob hematopoiesis (mob ntshav qab zib, thrombocytopenia, leukopenia, granulocytopenia).

Kev tsis haum tshuaj: pruritus, urticaria, tawv nqaij pob xoo, suav nrog maculopapular thiab bullous), erythema.

Lwm yam: pom kev pom.

Cov kev mob tshwm sim heev ntawm sulfonylureas: erythropenia, agranulocytosis, hemolytic anemia, pancytopenia, kev tsis haum vasculitis, ua rau lub siab ua rau lub siab tsis ua haujlwm.

Cov Yuav Tsum Tau Ua

- hom ntshav qab zib 1

- uas ketoacidosis, mob ntshav qab zib precoma, mob ntshav qab zib coma,

Mob raum thiab / lossis nplooj siab tsis ua haujlwm,

- muaj hnub nyoog txog 18 xyoo

- lub sijhawm pub niam mis (lactation),

- mob plab lactose tsis txaus ntseeg, lactase deficiency lossis glucose-galactose malabsorption,

- Kev ua haujlwm tsis haum rau gliclazide lossis ib qho ntawm cov tsis nyiam ntawm cov tshuaj, mus rau lwm yam sulfonylurea derivatives, rau sulfonamides.

Nws tsis pom zoo kom siv cov tshuaj ib txhij ua ke nrog phenylbutazone lossis danazole.

Nrog ceev faj: laus lub hnub nyoog, tsis xwm yeem thiab / los yog tsis muaj zaub mov noj tsis txaus, kab mob loj heev ntawm cov hlab plawv (suav nrog rau cov hlab plawv, atherosclerosis), hypothyroidism, adrenal lossis pituitary tsis txaus, hypopituitarism, raum thiab / lossis daim siab ua haujlwm, kev kho mob ntev nrog corticosteroids, cawv, tsis txaus ntseeg piam thaj-6-phosphate dehydrogenase.

Cev xeeb tub thiab lactation

Tsis muaj kev paub nrog gliclazide thaum cev xeeb tub. Cov ntaub ntawv hais txog kev siv lwm cov sulfonylurea derivatives thaum cev xeeb tub muaj tsawg.

Hauv kev kawm txog cov tsiaj hauv chaw sim, teratogenic cov teebmeem ntawm gliclazide tsis tau txheeb xyuas.

Txhawm rau kom txo cov kev pheej hmoo ntawm lub cev tsis xwm yeem, kev tswj hwm qib siab (kev kho kom haum) ntawm ntshav qab zib mellitus yog qhov tsim nyog.

Qhov ncauj hypoglycemic qhov ncauj thaum cev xeeb tub tsis siv. Cov tshuaj ntawm cov kev xaiv rau kev kho mob ntshav qab zib hauv cov poj niam cev xeeb tub yog cov tshuaj insulin. Nws raug nquahu kom hloov qhov kev noj tshuaj ntawm qhov ncauj hypoglycemic nrog insulin txoj kev kho ob leeg nyob rau hauv rooj plaub ntawm kev npaj cev xeeb tub, thiab yog tias cev xeeb tub tau tshwm sim thaum noj cov tshuaj.

Ua rau hauv kev txiav txim siab tsis muaj cov ntaub ntawv hais txog kev noj cov gliclazide hauv cov kua mis thiab kev pheej hmoo ntawm kev noj qab haus huv neonatal hypoglycemia, kev pub mis niam yog contraindicated thaum kho cov tshuaj.

Siv rau menyuam yaus

Contraindicated rau cov menyuam yaus hnub nyoog qis dua 18 xyoo.

Cov tsos mob hypoglycemia, tsis hnov qab nco qab, mob ntshav qab zib tsis nco qab.

Kev Kho Mob: yog tias tus neeg mob nco qab, noj qab zib sab hauv.

Tej zaum qhov kev txhim kho ntawm cov kev mob hypoglycemic hnyav, nrog kev tsis nco qab, ntog lossis lwm yam mob puas siab ntsws. Yog tias cov tsos mob no tshwm sim, yuav tsum tau txais kev kho mob ceev ceev thiab tau mus pw hauv tsev kho mob sai.

Yog tias hypoglycemic coma yog xav tias yog lossis kuaj mob, 50 ml ntawm 40% dextrose (kua nplaum) daws tau nrawm nrawm rau hauv tus neeg mob. Tom qab ntawd, 5% dextrose (piam thaj) cov tshuaj tov yog muab tshuaj rau kom tswj tau qhov qib uas yuav tsum muaj piam thaj hauv ntshav.

Tom qab nws rov qab nco qab, nws yog ib qho tsim nyog yuav tsum muab cov neeg mob cov zaub mov nplua nuj nyob hauv cov khoom noj zom zaub mov kom yooj yim (kom tsis txhob rov qab txhim kho hypoglycemia).

Kev ua tib zoo soj ntsuam cov ntshav qabzib hauv qib siab thiab soj ntsuam ntawm tus neeg mob yuav tsum tau nqa tawm tsawg kawg 48 teev tom qab.

Tom qab lub sijhawm no, nyob ntawm tus neeg mob lub sijhawm, tus kws kho mob txiav txim siab txog qhov xav tau kev tshuaj xyuas ntxiv.

Kev lim ntshav tsis muaj txiaj ntsig vim yog qhov tseeb khi ntawm gliclazide ntxiv rau cov ntshav protein.

Glyclazide txhim kho cov nyhuv ntawm cov tshuaj anticoagulants (warfarin); koob tshuaj tiv thaiv cov tshuaj anticoagulant yuav tsum ua.

Miconazole (nrog kev tswj hwm kev tswj hwm thiab thaum siv lub ntsej muag rau ntawm lub qhov ncauj mucosa) txhim kho qhov kev tiv thaiv hypoglycemic ntawm cov tshuaj (hypoglycemia yuav dhau mus txog thaum tsis nco qab).

Phenylbutazone (kev tswj hwm kev tswj hwm) txhim kho cov nyhuv hypoglycemic ntawm cov tshuaj (hloov chaw vim plasma protein thiab / lossis qis tawm ntawm lub cev), ntshav qabzib tswj thiab tshuaj kho glyclazide yog tsim nyog, ob qho tib si thaum phenylbutazone tswj hwm thiab tom qab rho tawm.

Ethanol thiab ethanol-muaj cov tshuaj kho txhim kho kev mob ntshav qab zib, inhibiting qhov kev rov qab ua txhaum, tuaj yeem pab txhawb kev txhim kho hypoglycemic coma.

Thaum noj nrog lwm cov tshuaj hypoglycemic (insulin, acarbose, biguanides), beta-blockers, fluconazole, ACE inhibitors (captopril, enalapril), histamine H2 receptor blockers (cimetidine), MAO inhibitors, hypoglycemic thiab sulfanilamides thiab cim. kev phom sij ntawm hypoglycemia.

Nrog rau kev siv concomitant nrog danazol, ib qho mob ntshav qab zib tau sau tseg. Nws yog qhov tsim nyog los tswj theem ntawm cov ntshav qabzib thiab kho cov koob tshuaj ntawm gliclazide, ob qho tib si thaum lub sijhawm saib xyuas ntawm danazol thiab tom qab nws tshem tawm.

Chlorpromazine hauv kev txhaj tshuaj ntau dua (ntau dua 100 mg / hnub) nce cov piam thaj hauv cov ntshav, txo cov ntshav hauv insulin. Nws yog qhov tsim nyog los tswj cov ntshav qabzib thiab kho cov koob tshuaj ntawm gliclazide, ob qho tib si thaum tswj hwm ntawm chlorpromazine thiab tom qab nws tshem tawm.

GCS (cov kab ke, intraarticular, sab nraud, lub qhov ncauj tswj hwm) nce cov ntshav qabzib nrog txoj kev loj hlob ntawm ketoacidosis (txo qis hauv kam rau ua rau carbohydrates). Nws yog qhov tsim nyog los tswj cov ntshav qabzib thiab kho cov koob tshuaj ntawm gliclazide ob qho tib si thaum tswj hwm GCS thiab tom qab lawv rho tawm.

Ritodrine, salbutamol, terbutaline (iv) nce ntshav ntxiv hauv lub cev. Kev tswj ntshav qabzib tau pom zoo thiab, yog tias tsim nyog, hloov pauv ntawm tus neeg mob mus rau kev kho mob insulin.

Cov Cai Siv Tshuaj So

Cov tshuaj yog ntawv yuav tshuaj.

Cov lus thiab cov xwm txheej ntawm kev cia

Sau npe B. Cov tshuaj yuav tsum muab cia rau qhov chaw qhuav thiab tsaus, ntawm qhov chaw ncav cuag ntawm cov menyuam yaus ntawm qhov kub thiab txias tsis tshaj 25 ° C. Txee lub neej yog 3 xyoos.

Siv rau lub siab ua haujlwm tsis zoo

Nrog ceev faj nyob rau hauv daim siab tsis ua hauj lwm.

- Mob raum thiab / lossis daim siab ua haujlwm ntau.

Siv rau lub raum tsis zoo muaj nuj nqi

Siv rau cov neeg mob laus

Txoj kev kho yog nqa tawm tsuas yog ua ke nrog kev noj zaub mov kom muaj calorie tsawg, carb tsawg.

Nws yog ib qho tsim nyog yuav tsum tau soj ntsuam qib ntshav qabzib hauv cov ntshav ntawm lub plab khoob thiab tom qab noj mov, tshwj xeeb tshaj yog nyob rau thawj hnub ntawm kev kho mob nrog tshuaj.

Diabetalong® tuaj yeem tsuas yog kho rau cov neeg mob tau txais kev noj mov tsis tu ncua, uas tsim nyog noj tshais thiab muab cov khoom noj txaus rau hauv kev noj haus.

Thaum sau tshuaj, nws yuav tsum tau yug los rau hauv lub siab hais tias vim kev noj cov tshuaj sulfonylurea derivatives, hypoglycemia tuaj yeem txhim kho, thiab hauv qee kis muaj mob hnyav thiab ntev, yuav tsum tau pw hauv tsev kho mob thiab ntshav qabzib rau ob peb hnub. Kev mob ntshav qab zib feem ntau pib txhim kho nrog cov zaub mov tsis muaj calorie, tom qab ua haujlwm ntev lossis ua kom ib ce muaj zog, tom qab haus dej haus cawv, lossis thaum noj ntau yam tshuaj hypoglycemic nyob rau tib lub sijhawm.

Txhawm rau kom zam dhau kev txhim kho hypoglycemia, yuav tsum ceev faj thiab xaiv cov koob tshuaj yuav tsum tau, nrog rau kev muab cov neeg mob nrog cov ntaub ntawv tiav ntawm cov kev kho mob uas tau thov.

Nrog rau kev tawm dag zog ntawm lub cev thiab lub siab, thaum hloov kev noj zaub mov, kev hloov kho cov tshuaj Diabetalong® tsim nyog.

Tshwj xeeb tshaj yog rhiab rau qhov kev txiav txim ntawm cov tshuaj hypoglycemic yog cov neeg laus, cov neeg mob uas tsis tau txais kev noj zaub mov zoo, nrog rau lub xeev tsis muaj zog txaus, cov neeg mob uas muaj lub hlwb pituitary-adrenal tsis txaus.

Beta-blockers, clonidine, reserpine, guanethidine tuaj yeem npog qhov chaw kho mob tshwm sim ntawm hypoglycemia.

Cov neeg mob yuav tsum ceeb toom qhia txog kev pheej hmoo yuav muaj ntshav qab zib tsawg nyob rau hauv muaj ethanol, NSAIDs, thiab tshaib plab.

Hauv kev hais txog cawv cawv (haus cawv), nws kuj tseem muaj peev xwm tsim tau cov disulfiram-syndrome xws li (mob plab, xeev siab, xeev siab, ntuav, mob taub hau).

Kev phais mob thiab kev raug mob loj, kev kub nyhiab, kev kis kab mob nrog febrile syndrome yuav tsum muaj kev tshem tawm ntawm qhov ncauj hypoglycemic tshuaj thiab kev teem sijhawm kho tshuaj insulin.

Kev txhim kho ntawm cov tshuaj tiv thaiv theem nrab yog qhov ua tau (nws yuav tsum tau qhov txawv ntawm thawj qhov, uas qhov tshuaj tsis muab qhov kev cia siab tshwm sim ntawm kev kho mob thaum thawj zaug)

Tawm tsam keeb kwm ntawm kev kho cov tshuaj Diabetalong®, tus neeg mob yuav tsum tso tseg kev haus cawv thiab / lossis cov tshuaj cawv thiab muaj cov tshuaj thiab khoom noj khoom haus.

Thaum kho mob Diabetalong®, tus neeg mob yuav tsum tau txiav txim siab ntau ntau ntawm cov piam thaj thiab glycosylated hemoglobin hauv cov ntshav, thiab cov piam thaj hauv cov zis nyob rau hauv cov zis.

Cuam tshuam rau kev muaj peev xwm tsav tsheb thiab tswj cov tshuab

Thaum lub sijhawm kho mob, yuav tsum tau saib xyuas thaum tsav tsheb thiab koom nrog lwm yam kev phom sij uas yuav tsum muaj kev ntseeg ntau ntxiv thiab ceev ntawm cov kev tiv thaiv psychomotor.

Diabetalong - cov lus qhia rau kev siv

Ntshav qab zib yog ib yam kab mob uas siv tsis tau. Tus neeg mob tau yuam kom noj cov tshuaj uas tswj ntshav qab zib hauv nws lub neej.

Rau cov neeg mob uas muaj ntshav qab zib hom 1, qhov no yog insulin, thiab hom thib ob yog tshuaj sulfonylurea.

Diabetalong yog ib qho tshuaj hypoglycemic rau cov neeg muaj ntshav qab zib kom txo nws.

Cov tshuaj tau noj ntawm qhov ncauj, thiab vim yog lub sijhawm ntev, nws siv 1, tsawg dua 2 zaug hauv ib hnub.

Cov tshuaj yog tshuaj raws li yus tus kheej lossis hauv cov txheej txheem sib koom ua ke. Nws yog siv rau qee kis uas tom qab kev noj zaub mov pab tsis tau, tab sis kev noj tshuaj yuav tsum nrog kev noj zaub mov kom raug.

Kev Sau ua ke, daim foos tso tawm

Diabetalong muaj nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj dawb puag ncig. Lawv tau ntim rau hauv cov hlwv ntawm 10 daim thiab ib daim npav cardboard, qhov twg tuaj yeem los ntawm 3 txog 6 daim hlau.

Cov tshuaj muaj nyob hauv ob qhov tshuaj: 30 mg thiab 60 mg ntawm cov tshuaj nquag, uas yog gliclazide.

Ntu ntu ntawm cov tshuaj:

colloidal silicon dioxide,
lactose monohydrate,
calcium stearate
pyromellose
talcum hmoov.

Daim ntawv ntau npaum li cas yuav yog nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj nrog hloov kho tso tawm lossis nrog rau lub sijhawm ua haujlwm ntev.

Cov chaw muag tshuaj thiab tshuaj pharmacokinetics

Cov khoom siv tseem ceeb yog gliclazide, los ntawm cov khoom siv tshuaj lom neeg nws yog ib qho kev tso tawm ntawm lub cim thib ob ntawm sulfonylurea. Gliclazide tso rau pom cov kev ua haujlwm siab thiab kev nyab xeeb.

Nws tiv taus ntau hom kev lom neeg thiab muaj cov teebmeem hauv qab no:

tsub kom zus tau cov kev tsim cov tshuaj insulin, tso cai rau koj kom txo qis ntawm cov tshuaj hormone rau txhaj,
normalizes metabolism hauv carbohydrate,
nce cov kev ua ntawm pancreatic beta hlwb,
txo cov platelet fusion, uas txwv tsis pub thrombosis thiab lwm yam vascular pathologies.

Diabetalong yog kiag li nqus tom qab kev tswj hwm. Maj mam mus ntxiv hauv cov ntshav, nce mus txog qhov siab tshaj plaws 4-6 teev tom qab kev tswj hwm, qhia nws cov nyhuv rau 10-12 teev, tom qab ntawd nws cov concentration poob qis thiab tom qab 12 teev tshuaj raug tshem tawm ntawm lub cev.

Gliclazide yog metabolized feem ntau los ntawm daim siab, thiab tawm los ntawm lub raum.

Kev taw qhia thiab contraindications

Qhov laj thawj ntawm kev noj ntshav qab zib yog kev kuaj mob ntawm tus neeg mob - hom ntshav qab zib 2. Cov tshuaj raug txwv kom txo cov ntshav qab zib thaum ua raws li cov lus qhia txog kev noj zaub mov tsis zoo pab.

Tsis tas li, cov tshuaj yog kws kho raws li prophylactic rau cov kev mob tshwm sim los ntawm ntshav qab zib mellitus, feem ntau hloov pauv hauv cov qauv ntawm cov hlab ntsha nyob rau hauv tus ntawm glycemia siab.

Muaj cov qauv sib txuam rau cov tshuaj, lawv suav nrog:

ntshav qab zib hom 1
noj miconazole,
hepatic thiab lub raum tsis ua haujlwm,
lub sijhawm cev xeeb tub thiab pub niam mis,
muaj cov ketoacidosis uas mob ntshav qab zib, tsis nco qab lossis ua ntej lawm,
siab rhiab rau cov uas ua cov yeeb tshuaj,
ua txhaum ntawm cov lactose metabolism,
hnub nyoog mus deev.

Xyuam xim thiab tsuas yog nyob rau hauv kev saib xyuas ntawm tus kws kho mob, cov tshuaj yog siv:

thaum laus
cov neeg uas lawv cov zaub mov tsis xwm yeem,
cov neeg mob plawv
cov neeg mob uas mob ntshav qabzib-6-phosphate dehydrogenase tsis txaus,
tom qab lub sijhawm ntev ntawm glucocorticosteroid txoj kev kho,
quav cawv quav cawv
muaj raum lossis mob siab.

Hauv qhov no, tus kws kho mob yuav tsum txiav txim siab ntawm lub hauv paus ntawm cov ntaub ntawv muaj.

Cov khoom siv video los ntawm tus kws muab tshuaj:

Cov neeg mob tshwj xeeb

Rau cov neeg laus dua 65 xyoos, yuav tsum tau muab tshuaj kho kom ntau dua. Nyob rau hauv dav dav, cov tshuaj siv los ua raws li tib txoj cai.

Hauv lub sijhawm ntawm kev xeeb tub, cov tshuaj tau pom zoo kom hloov los ntawm kev siv tshuaj insulin kom txog thaum yug menyuam. Tsis muaj kev paub dhau los ntawm kev siv Diabetalong thiab lwm yam tshuaj glycoside thaum cev xeeb tub, yog li nws tsis muaj peev xwm txiav txim siab nws cov nyhuv ntawm cov menyuam hauv plab.

Thaum lub sijhawm lactation, cov tshuaj tseem tsis tuaj yeem siv, vim tias muaj qhov tshwm sim ntawm kev mob ntshav siab neonatal hypoglycemia hauv menyuam yaus. Yog li, pub niam mis rau tus pojniam uas mob tau raug txwv.

Cov neeg mob raum tsis ua haujlwm thiab lwm cov kab mob yuav tsum ua raws li cov tshuaj noj qis, tseem ceeb tshaj, yuav tsum tau saib xyuas txhua lub sijhawm ntawm tus kws kho mob.

Cov lus qhia tshwj xeeb

Ib qho mob tseem ceeb rau kev noj cov ntshav qab zib yog khoom noj xwm yeem. Nws yuav tsum ua raws li cov lus pom zoo rau pawg neeg mob no thiab kho tau raws sijhawm. Qhov no yog qhov tsim nyog los tshem tawm qhov kev pheej hmoo ntawm kev mob ntshav qab zib, uas yuav tshwm sim vim tsis muaj lub zog ntawm cov ntshav hauv cov ntshav.

Cov laj thawj uas ua rau kom muaj kev txo qis ntawm lub qog ntshav ntshav tuaj yeem yog:

tsis muaj kev saib xyuas los ntawm tus neeg mob ntawm nws tus kheej qhov mob,
tsis-saib kev noj cov zaub mov thiab lub cev ntau npaum li cas, tshaib plab, tsis npaj zaub mov tsis haum,
raum lossis mob siab raum tsis ua haujlwm,
haus tshuaj ntau dhau
cov kab mob endocrine system,
mismatch ntawm qib ntawm kev qoj ib ce thiab tus nqi ntawm carbohydrates tau txais
concurrent saib xyuas ntawm ntau cov tshuaj.

Phiv thiab haus tshaj

Cov kev phiv loj los ntawm kev noj tshuaj yog:

mob taub hau
hemolytic yam anemia,
ua txhaum ntawm saj
ua xua, feem ntau tshwm sim los ntawm daim tawv nqaij ua pob.

Lwm cov tsos mob tuaj yeem tshwm sim:

cramps
kiv taub hau
ua txhaum ntawm kev rhiab
tshee
ua txhaum ntawm kev ua pa thiab nqos muaj nuj nqi,
siab nce
tsis tshua muaj qhov pom kev zoo
mob siab ntawm hom mob cholestatic.

Hauv qhov no, nws yog ib qho tsim nyog kom tsum tsis txhob noj cov tshuaj thiab xaiv cov tshuaj analogues raws lwm cov khoom siv.

Kev noj tshuaj ntau dhau ntawm cov tshuaj yuav ua tau yog tias koj muaj kev ywj pheej ntau tshaj qhov tau noj tshuaj. Nws lub ntsiab tseem ceeb yog hypoglycemia, mus txog tom qab tsis nco qab.

Nrog cov ntshav tsis txaus ua kom tsis txhob mob, qhov tshuaj yuav tsum raug txo kom tsawg, thiab cov nqi ntawm cov carbohydrates hauv cov zaub mov yuav tsum nce ntxiv. Tus mob hypoglycemic coma, cov tshuaj kua ntshav qab zib tau muab tshuaj.

Kev cuam tshuam nrog lwm yam tshuaj

Diabetalong nquag sib cuam tshuam nrog ntau yam tshuaj yeeb tshuaj, yog li ua ntej koj pib noj nws, koj yuav tsum paub koj tus kheej nrog qhov zoo tshaj no.

Yog li, thaum muaj kev tswj hwm tib lub sijhawm:

nrog cov cawv yuav ua rau lub ntsej muag hypoglycemia,
nrog Danazol, kev ua kom mob ntshav qab zib yog ua kom pom, uas txo cov nyhuv ntawm cov tshuaj,
nrog miconazole, cov nyhuv ntawm gliclazide ua kom zoo dua, uas tuaj yeem pab txhawb kev tsim cov ntshav hauv lub cev, tib yam tshwm sim nrog lwm cov kab mob ntshav qab zib,
nrog chlorpromazine, uas txo cov kev tsim tawm ntawm cov tshuaj insulin, cov tshuaj ntawm cov tshuaj tseem ceeb txo,
nrog tetracosactide thiab glucocorticosteroids tuaj yeem ua rau muaj kev txhim kho ketoacidosis thiab txo qis hauv kev ua kom tau cov carbohydrate,
nrog Wafarin thiab lwm coagulants txhim kho nws cov nyhuv.

Kev tshuaj xyuas ntawm cov kws kho mob pom tias Diabetalong ua tau zoo tshaj plaws hauv kev txo qis ntshav qab zib, txawm li cas los xij, nws tsis tuaj yeem siv tas li.

Hauv qhov no, cov kab mob analogues ntawm Diabetalong tau muab tshuaj, uas muaj ntau heev:

Diabetalong thiab Diabeton tau tsim nyob rau hauv cov khoom siv tib yam, tab sis cov tshuaj thib ob yog pom tias qhov ua tau zoo dua, vim qhov txiaj ntsig ntawm nws cov kev ua tiav tiav sai dua, tab sis tus nqi ntawm cov tshuaj no yog 2 zaug siab dua. Glyclazide yog ib qho yuav luag tiav.

Glucophage ntev muaj metformin hauv nws cov lus sib xyaw thiab tuaj yeem ua ke nrog insulin thiab lwm yam tshuaj los txo cov ntshav qab zib.

Peb pom zoo lwm cov ntsiab lus hais txog

Kev tswj ntshav qab zib mob ntshav qab zib

Nws tsis yog ib txwm ua tau los tswj hom 2 mob ntshav qab zib mellitus tsuas yog nrog kev pab ntawm cov khoom noj uas tsis muaj carb thiab cov leeg nqaij mob. Thiab nws yog ib qho tsim nyog los tawm tsam hyperglycemia, vim hais tias kev kho mob tsis paub yuav ua rau muaj kev mob hnyav.

Ntawm qhov kev phom sij tshaj plaws yog cov teeb meem plawv. Diabetalong (Latin Diabetalong), cov tshuaj hypoglycemic nrog rau lub sijhawm ntev lossis hloov pauv, yuav pab txo qhov kev pheej hmoo ntawm kev tsim CVD.

Pharmacological tau

Cov tshuaj tiv thaiv kev puas tsuaj ntawm cov tshuaj yog vim muaj cov nquag compound gliclazide. Cov ntsiav tshuaj muaj 30 lossis 60 mg ntawm qhov tseem ceeb thiab qhov tshwj xeeb: calcium stearate, hypromellose, talc, lactose monohydrate, colloidal silicon dioxide.

Diabetalong yog cov tshuaj ntawm 2 tiam sulfonylurea chav kawm.

Thaum nws nkag mus rau hauv cov hlab ntshav, gliclazide ua rau lub zog ntawm cov tshuaj tiv thaiv endogenous los ntawm β-hlwb ntawm cov txiav, ua kom nrawm rau kev siv cov piam thaj (nrawm nqaij glycogen synthase).

Tsis pub dhau ob peb hnub txij li hnub pib, glycemic profile yog li qub. Lub sijhawm sib nrug ntawm kev noj cov zaub mov hauv cov hnyuv mus rau kev tsim cov tshuaj endogenous insulin raug txo qis, thiab cov glycemic ntsuas los ntawm cov zaub mov raug txo kom tsawg.

Nws yog qhov xav paub tias 2 xyoos tom qab noj cov tshuaj, qhov siab ntawm insulin tom qab thiab C-peptide yog tswj. Qhov cuam tshuam rau lub cev hauv Diabetalong yog qhov nyuaj:

Regulates carbohydrate cov metabolism hauv,
Nws muaj cov txiaj ntsig ua haujlwm tiv thaiv kab mob,
Stimulates insulin secretion,
Nws muaj cov nyhuv hemovascular (suppresses platelet aggregation).

Thaum cov piam thaj nkag mus rau hauv cov ntshav, gliclazide ua kom sai rau cov kua dej. Nrog kev kho tas li, cov tshuaj ceeb toom:

Microvascular cov teeb meem - retinopathy (ib qho kev hloov ntawm txoj leeg ntshav ntawm retina) thiab nephropathy (mob raum ua haujlwm),
Cov teebmeem macrovascular - cov hlab ntsha tawg, plawv nres.

Cov tshuaj Pharmacokinetic

Los ntawm lub plab, cov tshuaj yog nqus tag nrho. Cov ntsiab lus siab tshaj plaws hauv cov hlab ntsha tau mus txog tom qab 2-6 teev, thiab rau cov ntsiav tshuaj nrog MV - 6-12 teev.

Kev kho mob nyhuv ntev li 24 teev, cov ntshav protein glycazide khi rau 85-99%. Hauv lub siab, cov khoom siv roj ntsha tau hloov pauv mus rau hauv cov khoom noj tshuaj, ib qho ntawm lawv muaj qhov zoo ntawm microcirculation. Ib nrab-lub neej yog 8-12 teev, rau cov ntsiav tshuaj nrog MB - 12-16 teev. Cov tshuaj siv tshuaj tawm los ntawm 65% nrog zis, los ntawm 12% nrog quav.

Sab sij huam

Qhov tsis xav ua rau lub plab zom mov tuaj yeem ua rau mob plab ua kom tsis txhob ua rau xeev ntuav, ntuav, mob plab. Los ntawm ib sab ntawm cov metabolism, hypoglycemia yog ua tau, rau cov kab mob circulatory - eosinophilia, cytopenia, ntshav liab. Ntawm ib feem ntawm daim tawv nqaij, kev fab tshuaj tiv thaiv thiab ua xaim tau. Los ntawm cov kev paub ntawm cov plab hnyuv siab raum muaj cov saj tsis sib xws, mob taub hau, tsis sib koom tes, tsis muaj zog.

Cov tshuaj sib cuam tshuam

Cov txiaj ntsig ntawm glycoside yog txhim kho los ntawm kev siv ua ke nrog nrog anabolic steroids, ACE inhibitors, β-blockers, cimetidine, fluoxetine, salicylates, MAO inhibitors, Flucanazole, Pentoxifylline, Miconazole, Theophylline, Tetracycline.

Muaj peev xwm ntawm glycoside tsis muaj zog thaum siv nrog concitantly nrog barbiturates, glucocorticoids, sympathomimetics, saluretics, rifampicin, tshuaj txwv tsis pub muaj menyuam, estrogens.

Yuav thov li cas

Glycloside yuav tsum noj nrog kev noj mov. Cov ntsiav tshuaj tau nqos tag nrho, ntxuav nrog dej hauv chav tsev kub. Tus kws endocrinologist tau xaiv cov koob tshuaj thiab kev kho mob rau tus kheej, coj mus rau theem ntawm tus kabmob thiab qhov tshuaj tiv thaiv tus mob ntshav qab zib rau cov tshuaj. Txog cov tshuaj Diabetalong, cov lus qhia rau kev siv pom zoo kom pib ntawm 30 mg thiab ib qho kev kho ntxiv hauv kev coj ua kom nce ntxiv (yog tias tsim nyog).

Yuav kom ua tiav cov txiaj ntsig siab tshaj plaws, nws yog ib qho tseem ceeb kom ua raws li txoj cai yooj yim.

Cov koob tshuaj txhua hnub tau noj ib zaug, qhov zoo tshaj plaws - thaum sawv ntxov,
Tus nqi ntawm cov tshuaj tuaj yeem hloov kho tsis pub dhau 30 -120 mg / hnub,
Yog tias koj tsis dhau lub sijhawm nkag, koj tuaj yeem ua tsis tau ob zaug ntxiv los ntawm lub sijhawm tom ntej,
Thaum xam qhov kev xav tshuaj, tus kws kho mob yuav siv sij hawm rau hauv kev nyeem ntawv ntawm glucometer thiab HbAlc.

Nrog cov txiaj ntsig tsis txaus, qhov kev coj ua tau nce (tom qab kev pom zoo nrog tus kws kho mob), tab sis tsis ntxov dua ib hlis tom qab txhaj tshuaj glycoside thawj zaug. Txhua 2 lub lis piam, nrog kev them nyiaj tsis tiav ntawm glycemia, koj tuaj yeem nce lub koob tshuaj.

Nws yog ib qho tseem ceeb xav txog tias 1 ntsiav tshuaj ntawm Diabetalong PV muaj 60 mg ntawm glyclazide, qhov no sib haum rau 2 ntsiav tshuaj ntawm Diabetalong MV 30 mg txhua.

Thaum hloov cov ntshav qab zib rau gliclazide los ntawm lwm cov tshuaj hypoglycemic, so tsis tsim nyog, tshwj tsis yog sulfonylurea derivatives. Thawj koob tshuaj hauv qhov teeb meem no yog tus qauv - 30 mg, yog tias tus kws kho mob endocrinologist tsis tau hais nws txoj cai.

Hauv txoj kev kho mob nyuaj, Diabetalong siv ua ke nrog ntau hom tshuaj insulin, biagudins, α-glucosidase inhibitors. Nrog kev ceev faj, cov tshuaj yog tawm rau cov neeg mob ntshav qab zib los ntawm kev mob ntshav qab zib (mob ntshav dej cawv, ua haujlwm lub cev lossis kis las, tshaib plab, muaj kev ntxhov siab tom qab). Hemopoietic kev ua haujlwm yog qhov cuam tshuam nrog kev txhim kho kev mob ntshav tsis txaus, thrombocytopenia, leukopenia, granulocytopenia.

Kev tiv thaiv kev nyab xeeb

Txhawm rau kom tsis txhob mob ntshav qab zib, nws yog ib qho tseem ceeb rau lub sijhawm ntawm kev siv tshuaj rau kev noj zaub mov, kom tiv thaiv kev tawg loj hauv cov zaub mov, kom tshem tawm qhov ua kom muaj dej cawv kom tsawg. Kev tswj hwm khov kho ntawm β-blockers tuaj yeem cuam tshuam cov tsos mob ntawm kev mob ntshav qab zib.

Lub xeev hypoglycemic tuaj yeem lees paub los ntawm kev mob taub hau, kev sib koom tes tsis sib haum, tsis muaj kev tiv thaiv ntawm kev tshaib kev nqhis, kev nyuaj siab, tsaus muag, tsaus muag, tsis pom kev. Cov tshuaj tiv thaiv adrenergic kuj tseem ua kom pom tseeb: ntxhov siab, tawm hws, poob rau hauv cov ntshav siab, mob plawv, lub plawv tawg. Dyspeptic cuam tshuam, cuam tshuam nyob rau hauv lub suab ntawm tso quav, thiab cov tawv nqaij tawv (ua pob ua si, tsis xis nyob, erythema, urticaria, Quincke's edema) yog cov yam ntxwv.

Cov kev kho mob zoo tsis tuaj yeem tsis tuaj yeem tsis muaj lub cev kev noj qab haus huv tsawg. Vim muaj kev phom sij txaus ntshai, cov neeg tsav tsheb yuav tsum noj cov tshuaj nrog ceev faj. Cov lus pom zoo ib yam rau cov neeg sawv cev ntawm kev ua haujlwm uas muaj feem cuam nrog kev hloov siab thiab kev ua haujlwm siab.

Pathologies ntawm lub siab thiab cov kua tsib ducts ua rau tus kab mob siab, ua kom muaj enzyme kev ua si.

Yog hais tias tus neeg raug tsim txom nco qab, nws yuav tsum noj khob noom, haus ib khob dej tshuaj yej lossis lwm qhov siab ntawm cov khoom noj kom ntau. Tom qab mob zoo dua, tus kws kho mob endocrinologist xav tau kev sab laj los kho qhov tshuaj lossis hloov cov tshuaj.

Analogues ntawm cov tshuaj

Raws li cov nquag tivthaiv rau Diabetalong, cov tshuaj analogue yuav yog cov tshuaj Glidiab muaj nqis txog 140 rubles. Cov kws kho mob muab cov mob ntshav qab zib thiab cov tshuaj ntshav qab zib MV rau qhov siab tshaj ntawm tus nqi ntawm 286 txog 318 rubles. Ntawm kev npaj ua lus, Glyclada kuj tseem tuaj yeem pom zoo.

Kev npaj nrog cov txiaj ntsig hypoglycemic zoo xws li Amaril, Glimepiride, Glemaz, Glyurenorm yuav zoo heev rau kev sib xyaw. Lawv raug xaj rau kev tiv thaiv hypersensitivity lossis lwm yam contraindications rau glycoside.

Kuaj Cov Ntshav Qab Zib

Tus kws kho mob ntshav qab zib uas tau ntsib ntau yam dhau los ntawm Diabetolong, hauv kev txheeb xyuas sau tseg nws qhov zoo:

Maj mam txhim kho ntawm cov ntsuas glucometer,
Zoo sib xyaw nrog lwm yam tshuaj,
Nqis tus nqi ntawm cov tshuaj
Lub peev xwm yuag poob thaum lub sijhawm tshuaj.

Tsis yog txhua tus neeg txaus siab rau qhov xav tau tas mus li (txog 5 zaug hauv ib hnub) kev tswj hwm glycemic, tab sis dhau sijhawm nws cov kev ntsuas nws tswj tau khov kho thiab xav tau kev txhim kho tus kheej tswj tau tsawg dua.

Feem ntau, Diabetalong yog ib qho tshuaj tiv thaiv kev tiv thaiv kev quav tshuaj uas ua kom lub cev glycemic zoo. Thaum siv kom raug, nws tuaj yeem tiv thaiv kev mob plawv thiab lwm yam mob hnyav ntawm ntshav qab zib hom 2.