Egipentin - cov lus piav qhia ntawm cov tshuaj, cov lus qhia rau kev siv, tshuaj xyuas

Tso koj saib

Cov Ntaub Ntawv Tam Sim No Xav Tau Index, ‰

Daim ntawv tso npe sau npe EGIPENTIN

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Lub vev xaib raug cai ntawm lub tuam txhab RLS ®. Lub encyclopedia tseem ceeb ntawm cov tshuaj thiab cov khoom muag ntawm cov khw muag tshuaj assortment ntawm Lavxias Internet. Daim ntawv teev cov tshuaj Rlsnet.ru muab cov neeg siv kev nkag mus rau cov lus qhia, tus nqi thiab cov lus piav qhia txog cov tshuaj, khoom noj tshuaj, khoom siv kho mob, khoom siv kho mob thiab lwm yam khoom lag luam. Cov lus qhia ntawm pharmacological suav nrog cov ntaub ntawv ntawm kev sib xyaw thiab daim ntawv tso tawm, kev nqis tes ua pharmacological, kev taw qhia rau kev siv, contraindications, kev phiv tshuaj, cuam tshuam tshuaj, hom kev siv tshuaj, cov tuam txhab tshuaj. Daim ntawv qhia cov tshuaj muaj nqi rau tshuaj thiab cov khoom lag luam tshuaj hauv Moscow thiab lwm lub nroog Lavxias.

Nws yog txwv tsis pub xa, theej, tshaj tawm cov ntaub ntawv yam tsis tau txais kev tso cai los ntawm RLS-Patent LLC.
Thaum hais cov ntaub ntawv xov xwm luam tawm nyob rau ntawm nplooj ntawv ntawm lub xaib www.rlsnet.ru, qhov txuas mus rau qhov chaw ntawm cov ntaub ntawv xav tau.

Ntau ntau yam nthuav

Qoob loo.

Kev ua lag luam siv cov ntaub ntawv tsis raug tso cai.

Cov ntaub ntawv yog npaj rau cov kws kho mob.

Kev piav qhia ntawm qhov kev txiav txim ntawm pharmacological

Antiepileptic siv yeeb siv tshuaj. Tus txheej txheem tshuaj lom neeg zoo ib yam li GABA, uas ua rau cov nres hauv nruab nrab cov leeg nres tsheb. Tus txheej txheem ntawm kev ua ntawm gabapentin ntseeg tau tias muaj qhov sib txawv los ntawm lwm cov anticonvulsants ua yeeb yam dhau los ntawm GABA synapses (suav nrog valproate, barbiturates, benzodiazepines, GABA transaminase inhibitors, GABA uptake inhibitors, GABA agonists thiab GABA prodrugs). Hauv kev tshawb fawb hauv vitro tau pom tias gabapentin yog tus cwj pwm los ntawm qhov pom muaj qhov tshiab peptide binding site nyob hauv nas cov ntaub so ntswg, nrog rau cov kabmob hippocampus thiab cerebral cortex, uas tej zaum yuav cuam tshuam nrog cov haujlwm ua haujlwm anticonvulsant ntawm gabapentin thiab nws cov keeb kwm. Clinically cov ntsiab lus tseem ceeb ntawm gabapentin tsis khi rau lwm cov tshuaj sib luag thiab cov neurotransmitter receptors hauv lub hlwb, suav nrog nrog GABAA-, GABAB-, benzodiazepine receptors, nrog NMDA receptors.

Thaum kawg, tus mechanism ntawm kev ua ntawm gabapentin tsis tau teeb tsa.

Cov Tshuaj Hauv Tshuaj

Antiepileptic siv yeeb siv tshuaj. Tus txheej txheem tshuaj lom neeg zoo ib yam li GABA, uas ua rau cov nres hauv nruab nrab cov leeg nres tsheb. Tus txheej txheem ntawm kev ua ntawm gabapentin ntseeg tau tias muaj qhov sib txawv los ntawm lwm cov anticonvulsants ua yeeb yam dhau los ntawm GABA synapses (suav nrog valproate, barbiturates, benzodiazepines, GABA transaminase inhibitors, GABA uptake inhibitors, GABA agonists thiab GABA prodrugs). Hauv kev tshawb fawb hauv vitro tau pom tias gabapentin yog tus cwj pwm los ntawm qhov pom muaj qhov tshiab peptide binding site nyob hauv nas cov ntaub so ntswg, nrog rau cov kabmob hippocampus thiab cerebral cortex, uas tej zaum yuav cuam tshuam nrog cov haujlwm ua haujlwm anticonvulsant ntawm gabapentin thiab nws cov keeb kwm. Clinically cov ntsiab lus tseem ceeb ntawm gabapentin tsis khi rau lwm cov tshuaj sib luag thiab cov neurotransmitter receptors hauv lub hlwb, suav nrog nrog GABAA-, GABAB-, benzodiazepine receptors, nrog NMDA receptors.

Thaum kawg, tus mechanism ntawm kev ua ntawm gabapentin tsis tau teeb tsa.

Cov Tshuaj Pharmacokinetics

Gabapentin yog nqus tau los ntawm lub plab zom mov. Tom qab kev noj mov ntawm Cmax gabapentin hauv plasma tau tiav tom qab 2-3 teev. Kev noj cov zaub mov tsis raug cai yog li 60%. Txais tos tib lub sijhawm cov zaub mov (nrog rau cov neeg uas muaj cov rog hauv cov rog) tsis muaj kev cuam tshuam cov pharmacokinetics ntawm gabapentin.

Gabapentin tsis khi rau cov plasma protein thiab muaj Vd ntawm 57.7 L. Hauv cov neeg mob uas muaj qaug dab peg, qhov ntau ntawm gabapentin nyob rau hauv cov kua hlwb cerebrospinal yog 20% ​​ntawm cov tshuaj tiv thaiv ntshav Css nyob rau thaum xaus ntawm lub sijhawm noj tshuaj.

Gabapentin tsuas yog tawm ntawm lub raum xwb. Tsis muaj cov cim qhia ntawm biotransformation ntawm gabapentin hauv tib neeg lub cev tau pom. Gabapentin tsis yog qhov tseem ceeb rau cov tshuaj oxidases hauv cov tshuaj metabolism hauv. Kev rho tawm yog qhov zoo tshaj plaws piav txog kev siv hom qauv. T1 / 2 yog noj-koob thiab thaj tsam li 5-7 teev.

Kev Ntsiav Tshuaj Gabapentin yog txo qis rau cov neeg laus thiab cov neeg mob uas tsis muaj mob raum. Tus lej qis tus nqi tas mus li, ntshav thiab lub raum tshem tawm ntawm gabapentin yog ncaj qha kev sib npaug rau creatinine tshem tawm.

Gabapentin tshem tawm los ntawm cov ntshav los ntawm hemodialysis.

Plasma gabapentin ntau nyob rau hauv cov menyuam yaus zoo ib yam li cov neeg laus.

Siv thaum cev xeeb tub

Nws muaj peev xwm ua tau thaum cev xeeb tub tsuas yog qhov xav pom ntawm kev kho mob ntau dua qhov kev pheej hmoo rau menyuam hauv plab (kev tshawb fawb txaus thiab tswj tau zoo hauv cov pojniam cev xeeb tub tsis tau ua).

FDA qeb ntawm kev nqis tes ua rau tus menyuam yog C.

Thaum lub sijhawm kho mob, kev pub mis niam yuav tsum tso tseg (gabapentin kis mus rau niam mis thaum noj ntawm qhov ncauj).

Sab sij huam

Los ntawm ib sab ntawm lub hauv nruab nrab cov hlab hlwb thiab peripheral lub paj hlwb: amnesia, ataxia, tsis meej pem, kev tsis sib haum xeeb ntawm kev txav ntawm kev txav, kev nyuaj siab, kiv taub hau, lub cev tsis muaj zog, ua rau lub zog poob siab, nystagmus, tsaug zog, tsis tuaj yeem xav, tshee, ua tsis taus pa, amblyopia, diplopia, hyperkinesia, zuj zus, qaug zog los yog tsis muaj reflexes, paresthesia, ntxhov siab, kev ua siab ntev, ua tsis taus.

Los ntawm lub plab zom mov: hloov pauv ntawm cov hniav staining, mob raws plab, nce siab, ua lub qhov ncauj qhuav, xeev siab, ntuav, pom lub cev, tsis nco qab, mob caj pas, mob plab, mob plab, hloov hauv daim siab ua haujlwm.

Los ntawm cov kab mob hemopoietic: leukopenia, cov ntshav dawb tsawg zuj zus suav, thrombocytopenic purpura.

Los ntawm kev ua pa: rhinitis, pharyngitis, hnoos, mob ntsws.

Los ntawm cov leeg musculoskeletal: myalgia, arthralgia, pob txha lov.

Los ntawm cov hlab plawv system: arterial tawg, tshwm sim ntawm vasodilation.

Los ntawm cov kab mob urinary: mob txeeb zig, mob tso zis.

Kev tsis haum tshuaj: erythema multiforme, Stevens-Johnson syndrome.

Kev siv tshuaj ntxuav muag: maceration ntawm daim tawv nqaij, pob txuv, khaus, ua pob.

Lwm yam: mob nraub qaum, qaug zog, mob peripheral edema, impotence, asthenia, malaise, o ntawm lub ntsej muag, qhov hnyav nce, kev ua yuam kev raug mob, asthenia, mob khaub thuas xws li mob ntshav qab zib, kev hloov pauv hauv cov ntshav qab zib, hauv cov menyuam yaus - kis kab mob, kis mob otitis.

Tsuas tshuaj thiab tswj hwm

Sab hauv, tsis hais txog pluas noj.

Postherpetic neuralgia: nyob rau 1 hnub ntawm kev kho mob - 300 mg / hnub ib zaug, hnub thib 2 - 1600 mg / hnub (hauv 2 koob tshuaj), nyob rau hnub thib 900 mg / hnub (hauv 3 koob tshuaj). Yog tias tsim nyog, txhawm rau txo qhov mob hauv ib koob tom qab, koj tuaj yeem nce ntxiv mus rau 1800 mg / hnub (hauv 3 koob tshuaj).

Epilepsy (ua ib qho cuab yeej ntxiv): rau cov neeg mob uas muaj 12 xyoos rov saud - 900-1800 mg / hnub (hauv 3 koob). Qhov kev siv thawj zaug yog 300 mg 3 zaug hauv ib hnub, yog tias tsim nyog, nce qhov koob tshuaj rau 1800 mg / hnub. Qhov koob tshuaj txhua hnub yuav tsum tsis pub tshaj 3600 mg. Cov menyuam hnub nyoog 3-12 xyoo - koob tshuaj thawj zaug ntawm 10-15 mg / kg / hnub (hauv 3 koob tshuaj), cov koob tshuaj uas tau xaiv yog raug xaiv los ntawm kev suav rau 3 hnub.

Rau cov menyuam yaus hnub nyoog 5 xyoos thiab laus dua, qhov kev siv tshuaj zoo yog 25–35 mg / kg / hnub, rau cov menyuam muaj hnub nyoog 3-4 xyoo - 40 mg / kg / hnub (hauv 3 koob tshuaj).

Qhov sij hawm ntau ntawm kev muab tshuaj yuav tsum tsis pub tshaj 12 teev.

Kev tshem tawm gabapentin thiab / lossis ntxiv ib qho ntxiv ntawm cov tshuaj anticonvulsant rau kev kho mob yog nqa tawm maj dhau ib ntus tsawg kawg 1 lub lis piam.

Hauv cov neeg mob (ntau dua 12 xyoos) uas lub raum tsis ua haujlwm (qhov tsis muaj lub peev xwm ua kom tsawg dua 60 ml / min) lossis cov neeg mob tau txais kev kho mob hemodialysis, qhov tshuaj txhaj txo. Nrog rau kev tshem tawm tsawg kawg 60 ml / min - 900–3600 mg / hnub, nrog kev tshem 30–59 ml / min - 400–1400 mg / hnub, 15–29 ml / min - 200–700 mg / hnub, tsawg dua 15 ml / min - 100-300 mg / hnub. Rau cov neeg mob hemodialysis, qhov yuav tsum tau txhaj tshuaj ntxiv rau tom qab-hemodialysis yog 125–350 mg tom qab txhua ntu 4 teev ntawm hemodialysis.

Kev sib cuam tshuam nrog lwm yam tshuaj

Kev sib tham tseem ceeb ntawm gabapentin thiab lwm yam tshuaj anticonvulsants (phenytoin, valproic acid, phenobarbital, carbamazepine), nrog rau cov tshuaj tiv thaiv kab mob hauv qhov ncauj uas muaj norethisterone thiab / lossis ethinyl estradiol, tseem tsis tau tsim.

Antacids txo qis kev noj qab haus huv ntawm gabapentin (hauv kev tshawb fawb thaum noj nrog Maalox, lub cev kev nyab xeeb ntawm gabapentin raug txo qis 20%, thaum noj 2 teev tom qab noj Maalox, los ntawm 5%).

Cimetidine me ntsis txo qhov kev nthuav tawm ntawm gabapentin.

Naproxen (ntawm koob tshuaj 250 mg), pom meej, nce qhov nqus ntawm gabapentin (ntawm koob tshuaj 125 mg) los ntawm 12 txog 15%. Gabapentin tsis cuam tshuam rau qhov kev siv pharmacokinetic ntawm naproxen. Tsis tshua muaj kev cuam tshuam loj heev ntawm cov tshuaj no hauv cov koob pom zoo yuav tsis paub.

Morphine (60 mg) thaum noj 2 teev tom qab noj gabapentin (600 mg) nce AUC ntawm gabapentin los ntawm 44%.

Cov kev ceev faj rau kev siv

Gabapentin yuav tsum tsis txhob raug rau cov neeg mob hnub nyoog qis dua 12 xyoos nrog kev txo qis raum (tsis muaj kev tshawb fawb tau tshawb nrhiav). Cov kev ceev faj tau muab rau cov neeg laus (kev mob ntsig txog lub hnub nyoog lub raum feem ntau muaj feem ntau dua, cov koob tshuaj tau teem raws li creatinine tshem tawm).

Thaum noj gabapentin, koj yuav tsum tsis txhob tsav tsheb thiab siv cov cuab yeej muaj kuab uas yuav tsum muaj kev saib xyuas ntau ntxiv.

Cov lus qhia tshwj xeeb rau kev txais neeg kawm

Thaum muab sib xyaw nrog morphine, nws yog ib qho tsim nyog yuav tsum tau ua raws li kev tswj hwm cov kev mob tshwm sim zoo ntawm lub hauv nruab nrab ntawm cov leeg hlwb. Cov koob tshuaj gabapentin thiab morphine yog txo qis.

Gabapentin yuav tsum noj tsis pub dhau 2 teev tom qab noj tshuaj antacid.

Thaum txiav txim siab cov protein nyob hauv cov zis siv Ames N-Multistix SG kuaj, cov txiaj ntsig tsis zoo tuaj yeem tau nrog cov kev sib xyaw ua ke ntawm gabapentin nrog lwm cov anticonvulsants, yog li ntawd nws raug nquahu kom siv ntau txoj hauv kev.

Kev ntsuas rau siv

Kev kho mob ntawm neuropathic mob rau cov neeg laus hnub nyoog 18 xyoo, monotherapy ntawm ib nrab qaug dab peg nrog thiab tsis muaj kev xam pom dav dav hauv cov laus thiab cov menyuam hnub nyoog 12 xyoos, ua ib qho cuab yeej ntxiv hauv kev kho mob ib nrab nrog thiab tsis muaj kev xam phaj dav hauv cov laus thiab cov menyuam hnub nyoog 3 xyoos thiab laus dua.

Pharmacological kev txiav txim

Antiepileptic siv yeeb siv tshuaj. Tus txheej txheem tshuaj lom neeg zoo ib yam li GABA, uas ua rau cov nres hauv nruab nrab cov leeg nres tsheb. Tus txheej txheem ntawm kev ua ntawm gabapentin ntseeg tau tias muaj qhov sib txawv los ntawm lwm cov anticonvulsants ua yeeb yam dhau los ntawm GABA synapses (suav nrog valproate, barbiturates, benzodiazepines, GABA transaminase inhibitors, GABA uptake inhibitors, GABA agonists thiab GABA prodrugs).

Lub Npe Tsis Muaj Npe International

Tshuaj INN - Gabapentin.

Egipentin (Lub npe thoob ntiaj teb Gabapentin) yog cov tshuaj siv hauv kev kho mob ntawm kev mob vwm, nrog los ntawm kev chua leeg ntau.

Hauv qhov kev faib tawm thoob ntiaj teb ATX, cov tshuaj muaj chaws N03AX12.

Tso cov ntaub ntawv thiab cov nyob ua ke

Cov nyhuv pharmacological tau ua tiav los ntawm kev suav nrog gabapentin hauv cov tshuaj no. Tsis tas li, cov tshuaj muaj pes tsawg leeg suav nrog povidone, poloxamer, crospovidone, magnesium stearate, hydrolase.

Cov tshuaj no muaj nyob hauv daim ntawv ntawm cov tsiav tshuaj, txhua ntawm suav nrog tsawg kawg 300 mg ntawm cov tshuaj nquag. Cov tshuaj ntsiav tau ntim hauv cov hlwv ntawm 20 pcs. 3 lossis 6 lub hlwv tuaj yeem ntim hauv thawv ntawv thawv.

Yuav ua li cas noj egipentin?

Cov tshuaj yog npaj rau kev tswj hwm qhov ncauj. Kev muab tshuaj rau noj yog xaiv rau hauv kev txiav txim qhov hnyav ntawm cov kws kho mob hauv kev soj ntsuam. Feem ntau, kev txhaj tshuaj txaus ntawm 300 rau 600 mg rau ib hnub yog txaus rau txo cov tsos mob. Yog tias tsim nyog, nws tuaj yeem raug nce ntxiv rau 900 mg hauv ib hnub.

Nrog kev ceev faj, cov tshuaj yuav tsum tau siv yog tias nce ntxiv hauv kev muaj mob vwm yog qhov tshwm sim ntawm lub cev puas.
Cov tshuaj yog npaj rau kev tswj hwm qhov ncauj.
Kev kho mob ntawm cov neeg mob ntshav qab zib mellitus, feem ntau, yog ua tiav hauv kev txo qis.

Los ntawm cov leeg nqaij thiab cov leeg sib txuas

Siv Egipentin yuav ua rau mob mob pob txha. Muaj qee zaus, tawm tsam keeb kwm yav dhau los ntawm kev noj tshuaj, qhov pom ntawm edema thiab tawv ncauj ntawm cov pob qij txha, mob leeg thiab mob caj dab yog cai. Tsis tas li ntawd, cov tshuaj no tuaj yeem tsim cov kev xav ua kom ua ntej bursitis, mob nqaij thiab txha.

Lub plab zom mov

Soj ntsuam microbiology ntawm Egipentin yog xws li tias nrog kev siv cov tshuaj tsis tu ncua, kev ua haujlwm tsis tu ncua ntawm lub plab zom mov. Cov tshuaj no tuaj yeem ua rau stomatitis, gastroenteritis, glossitis, esophageal hernia, proctitis, thiab lwm yam. Cov tshuaj muaj peev xwm ua rau kev nce ntxiv hauv cov ntshav ntawm txoj hnyuv hauv plab. Ntxiv rau, cov neeg mob feem ntau muaj kev yws yws ntawm kev mob plab.

Hematopoietic plab hnyuv siab raum

Nrog rau kev siv ntawm Egipentin, thrombocytopenia, cov cim qhia ntawm anemia thiab purpura yuav tshwm sim.

Siv Egipentin yuav ua rau mob mob pob txha.
Soj ntsuam microbiology ntawm Egipentin yog xws li tias nrog kev siv cov tshuaj tsis tu ncua, kev ua haujlwm tsis tu ncua ntawm lub plab zom mov.
Tawm tsam keeb kwm yav dhau los ntawm kev siv Egipentin, kev puas siab ntsws xav tau.

Nruab nrab hauv lub paj hlwb

Kev siv cov Egipentin tuaj yeem ua rau kev txo qis ntawm qhov tsis zoo thiab qhov tsis hnov ​​mob ntawm qee cov pab pawg leeg. Tsis tas li ntawd, cov tshuaj sib txuam ntawm cov tshuaj yuav ua rau lub ntsej muag txhawm rau, los ntshav thiab mob cerebellar tsis ua hauj lwm. Tawm tsam keeb kwm yav dhau los ntawm kev siv Egipentin, kev hnov ​​ntawm kev zoo siab, hnov ​​qab thiab tawm tsam kev puas siab ntsws yuav tshwm sim. Muaj peev xwm ua tsis tau ntawm kev xav, kev nruab hnub pw tsaug zog thiab kev ua haujlwm tsis zoo.

Los ntawm cov hlab plawv system

Txoj kev loj hlob ntawm kev phiv los ntawm kev noj Egipentin los ntawm cov hlab plawv yog qhov tsis tshua muaj tshwm sim. Tib lub sijhawm, muaj kev pheej hmoo ntawm arrhythmia, vasodilation thiab dhia hauv ntshav siab.

Noj Egipentin tuaj yeem ua rau cystitis thiab mob tso zis ceev.
Ntxiv rau, cov tshuaj tuaj yeem ua rau kev loj hlob ntawm cov mob raum tsis zoo.
Tawm tsam keeb kwm yav dhau los ntawm kev noj cov tshuaj no, cov tsos mob ntawm kev tsis haum tshuaj, qhia ua pob khaus tawv nqaij, muaj peev xwm ua tau.

Tawm tsam keeb kwm yav dhau los ntawm kev noj cov tshuaj no, kev tawm tsam tuaj yeem tshwm sim, qhia tawm pob khaus thiab khaus khaus, o ntawm cov nqaij mos. Qee qhov tsis tshua muaj, kev ntsuas tshuaj tiv thaiv kev tsis taus yog tau pom.

Siv thaum cev xeeb tub thiab lactation

Qhov ua tau zoo thiab kev nyab xeeb ntawm kev siv cov tshuaj thaum cev xeeb tub thiab lactation tseem tsis tau muaj pov thawj, yog li ntawd, cov mob no yog qhov kev tiv thaiv rau kev siv Egipentin.

Cov hnub nyoog laus tsis yog contraindication rau kev siv tshuaj, tab sis kev hloov kho koob tshuaj yog nyob ntawm qhov ua haujlwm ntawm lub raum.
Cov tshuaj yaj yeeb tuaj yeem siv rau hauv kev kho mob ntawm kev puas ntsoog ntawm cov menyuam yaus tshaj 12 xyoos.
Lub caij nyoog ntawm cev xeeb tub thiab lactation yog kev sib kis rau kev siv Egipentin.
Yog tias koj noj Egipentin ntau dhau, raws plab yuav tshwm sim ntau zaus.
Egipentin tuaj yeem nce siab ntxiv ntawm phenytoin hauv ntshav ntshav thaum siv nws.

Cawv tau zoo

Thaum kho nrog cov tshuaj no, yuav tsum tsis txhob haus cawv.

Cov tshuaj uas muaj cov kev kho zoo sib xws xws li:

1. Neurontin.
2. Tebantin.
3. Gabagamma
4. Convalis.
5. Gabapentin.
6. Katena.
7. Gapantek li al.

Ntsiav Tshuaj Gabapentin. Tshuaj qaug dab peg Cov huab cua ntawm Lub Peb Hlis 16, 2016. HD version.

Chaw tsim tshuaj paus

Cov tshuaj yog tsim los ntawm Iberfar-Kev lag luam Cov Tshuaj.

Ib qho kev sib sau zoo sib xws yog Neurontin.
Raws li lwm txoj kev xaiv, koj tuaj yeem xaiv Tebantin.
Yog tias tsim nyog, cov tshuaj tuaj yeem hloov nrog Convalis.

Kev txheeb xyuas txog Egipentin

Svetlana, 32 xyoo, Oryol

Kuv tau txais kev txom nyem los ntawm tus mob vwm txij thaum yau los. Cov qaug dab peg siv los tshwm sim ntau zaus, tab sis tom qab ntawd cov kws kho mob khaws cov tshuaj thiab lawv tsum. Txog 3 xyoos dhau los, nws tau xeeb tub thiab poob ib tug menyuam. Tawm tsam no cov keeb kwm yav dhau los, kev chua leeg dua. Tus kws kho mob sau Egipentin. Siv cov tshuaj rau 6 lub hlis. Kuv txaus siab rau lub txiaj ntsig. Kuv tsis tau soj ntsuam ib qho tshwm sim dab tsi, tab sis maj mam muaj pes tsawg tus qaug dab peg. Txawm hais tias qhov tseeb ntawm kev txais tos ntawm cov nyiaj nres, rau ib xyoo tsis muaj qhov qaug dab peg.

Grigory, 26 xyoo, Vladivostok

Kuv tau sim ntau cov tshuaj kom tshem tawm qaug dab peg. Kev siv cov tshuaj Egyptin tau sau tseg los ntawm tus kws kho mob. Cov tshuaj no tsis haum rau kuv. Txij thawj hnub ntawm kev tswj hwm, phiv los ntawm txoj hnyuv txawv tshwm. Mob plab, ntuav, thiab zawv plab ua rau kuv tsum tsis txhob noj tshuaj.

Sab sij huam

Los ntawm ib sab ntawm lub hauv nruab nrab cov hlab hlwb thiab peripheral lub paj hlwb: amnesia, ataxia, tsis meej pem, kev tsis sib haum xeeb ntawm kev txav ntawm kev txav, kev nyuaj siab, kiv taub hau, lub cev tsis muaj zog, ua rau lub zog poob siab, nystagmus, tsaug zog, tsis tuaj yeem xav, tshee, ua tsis taus pa, amblyopia, diplopia, hyperkinesia, zuj zus, qaug zog los yog tsis muaj reflexes, paresthesia, ntxhov siab, kev ua siab ntev, ua tsis taus.

Los ntawm lub plab zom mov: hloov pauv ntawm cov hniav staining, mob raws plab, nce siab, ua lub qhov ncauj qhuav, xeev siab, ntuav, pom lub cev, tsis nco qab, mob caj pas, mob plab, mob plab, hloov hauv daim siab ua haujlwm.

Los ntawm cov kab mob hemopoietic: leukopenia, cov ntshav dawb tsawg zuj zus suav, thrombocytopenic purpura.

Los ntawm kev ua pa: rhinitis, pharyngitis, hnoos, mob ntsws.

Los ntawm cov leeg musculoskeletal: myalgia, arthralgia, pob txha lov.

Los ntawm cov hlab plawv system: arterial tawg, tshwm sim ntawm vasodilation.

Los ntawm cov kab mob urinary: mob txeeb zig, mob tso zis.

Kev tsis haum tshuaj: erythema multiforme, Stevens-Johnson syndrome.

Kev siv tshuaj ntxuav muag: maceration ntawm daim tawv nqaij, pob txuv, khaus, ua pob.

Lwm yam: mob nraub qaum, qaug zog, mob peripheral edema, impotence, asthenia, malaise, o ntawm lub ntsej muag, qhov hnyav nce, kev ua yuam kev raug mob, asthenia, mob khaub thuas xws li mob ntshav qab zib, kev hloov pauv hauv cov ntshav qab zib, hauv cov menyuam yaus - kis kab mob, kis mob otitis.

Cev xeeb tub thiab lactation

Cov kev tshawb fawb kawm txaus thiab nruj me ntsis ntawm kev nyab xeeb ntawm gabapentin thaum cev xeeb tub thiab lactation hauv tib neeg tsis tau ua. Yog tias tsim nyog, siv thaum cev xeeb tub thiab lactation yuav tsum ua tib zoo ntsuas cov txiaj ntsig ntawm txoj kev kho rau leej niam thiab muaj kev pheej hmoo rau tus menyuam lossis menyuam mos.

Gabapentin ua tawm hauv niam cov kua mis. Thaum siv thaum lactation, qhov xwm ntawm kev ua ntawm gabapentin ntawm tus menyuam tsis yog tsim.

Kev sib txuam

Thaum muab ua ke nrog lwm cov tshuaj anticonvulsants, cov lus qhia tsis tseeb ntawm cov zis muaj ntshav tsis zoo. Txhawm rau txiav txim siab cov protein nyob hauv cov zis, nws raug nquahu kom siv cov txheej txheem tshwj xeeb ntxiv ntawm cov dej nag ntawm sulfosalicylic acid.

Nrog rau kev siv ua ke nrog antacids, kev nqus ntawm gabapentin los ntawm kev mob plab zom mov qis dua.

Nrog rau kev siv ib txhij nrog felbamate, kev nce ntxiv hauv T1 / 2 ntawm felbamate yog ua tau.

Nrog rau kev siv ib txhij, ib rooj plaub ntawm kev nce ntxiv hauv kev mloog zoo ntawm phenytoin hauv ntshav cov ntshav tau piav qhia.

Siv rau menyuam yaus

Qhov ua tau zoo thiab kev nyab xeeb ntawm kev kho rau kev mob neuropathic hauv cov neeg mob hnub nyoog qis dua 18 xyoo tsis tau txhim tsa.

Qhov ua tau zoo thiab kev nyab xeeb ntawm gabapentin monotherapy nyob rau hauv kev kho mob ib nrab ntawm kev qaug dab peg hauv cov menyuam yaus uas muaj 12 xyoos rov hauv thiab kev kho ntxiv nrog gabapentin hauv kev kho mob ib nrab rau cov menyuam yaus hnub nyoog qis dua 3 xyoos tsis tau tsim