Dab tsi tuaj yeem hloov Tricor: ntsiav tshuaj analogues

Cov tshuaj Tricor belongs rau cov pab pawg ntawm lipid-txo cov tshuaj - fibrateCov. Cov tshuaj nquag ua haujlwm yog fenofibrate(derivativefibroic acid) yog tus cwj pwm los ntawm kev ua kom zoo ntawm PPARα thiab vim tias qhov ua kom zoo nkauj tsawg Apoprotein CIII thiab txhawb nqa lipoprotein lipaseua kom zoo dua lipolysisthiab nce ntxiv hauv cov ntshav tau los ntshav ntau ntxiv atherogenic lipoproteinsmuaj cov lej loj triglyceridesCov. Kev ua kom muaj zog ntawm PPARα tseem tsub kom sib ntxiv Cov kabmob AI thiab AII apoproteins.

Xws li ib qho kev cuam tshuam fenofibraterau lipoproteinspab txo kom tsawg feem VLDLthiab LDLmuaj apoprotein B, thiab nce zuj zus ntxiv HDLsuav nrog Cov kabmob AI thiab AII apoproteinsCov. Tsis tas li ntawd, qhov kev txiav txim fenofibratetsom rau kev kho cov txheej txheem ntau lawm thiab catabolism VLDL, uas ua rau kom muaj kev nce ntxiv hauv kev txav meej LDL thiab txo qhov khoom ntawm cov ntom ntom ntom thiab zoo zoo LDL(cov ntaub ntawv nce LDLpom nyob rau hauv cov neeg mob nrog atherogenic lipid phenotype thiab nrog kev txaus ntshai ntxiv rau txoj kev mob plawv (coronary heart disease).

Cov Chaw Kho Mob Ntsuam Xyuas lipid-txoslub zog fenofibratepom qhov txo qis hauv cov ncauj lus triglycerideslos ntawm 40-55% thiab tag nrho cov roj (cholesterol) los ntawm 20-25% thaum nce theem HDLlos ntawm 10-30%. Hauv cov neeg mob nrog hypercholesterolemiatheem LDLuas yog txo qis dua 20-35%, kev kho mob fenofibratecoj mus rau qhov txo hauv qhov piv: tag nrho cov roj (cholesterol) thiab HDL, apoprotein B thiab apoprotein AI, HDLthiab LDLuas yog cov cim phom sij atherogenicity.

Xav txog qhov cuam tshuam loj fenofibraterau cov ntsiab lus triglyceridesthiab LDLnws siv tau zoo hauv cov neeg mob nrog hypercholesterolemiatsis hais nws yuav los nrog hypertriglyceridemialos yog tsis cuam tshuam nrog rau lub tsev kawm theem nrab hyperlipoproteinemiaxws li piv txwv nrog hom 2 mob ntshav qab zib mellitus (sau tseg qhov ua tau zoo ntawm Traicor hauv mob ntshav qab zib) Thaum kho fenofibrateqhov tseem ceeb txo thiab txawm tias ua tiav ploj ntawm kev tso nyiaj extravascular yog ua tau roj(tuberose thiab leeg xanthomas).

Hauv cov neeg mob nrog cov ntsiab lus ntau dhau lipoproteinlossis fibrinogenuas tau txais kev kho mob fenofibrate, tau pom muaj qhov tseem ceeb txo hauv qhov ntsuas no. Kev Kho Mob fenofibratecoj mus rau qhov txo qis hauv qib C-reactive protein thiab lwm yam cim ntawm o.

Cov neeg mob nrog hyperuricemiathiab dyslipidemiatau txais cov txiaj ntsig ntxiv ntawm kev kho mob fenofibrateuas muaj uricosuric nyhuvua rau kom txo qis hauv cov ncauj lus uric acid txog 25%.

Cov kev tshawb fawb tsiaj thiab kev tshawb nrhiav soj ntsuam tom ntej tau pom tias muaj qis dua fenofibratekev sib sau ua ke platelet suavvim tias raug adenosine diphosphate, epinephrine thiab arachidonic acid.

Tricor 145 mg ntsiav tshuaj suav nrog micronized fenofibrate nyob rau hauv daim ntawv ntawm nanoparticles.

Hauv tib neeg cov ntshav, thawj zaug fenofibrate tsis pom. Lub plasma tseem ceeb khoom ntawm cov tshuaj metabolism hauv yog txiav txim siab fenofibroic acid.

Plasma Cmax fenofibrate yog pom tom qab 2-4 teev tom qab kev tswj hwm qhov ncauj ntawm cov tshuaj. Kev siv lub sijhawm ntev ntawm fenofibrate tsis ua rau muaj kev hloov pauv hauv nws lub plasma concentration, uas tsis hais tus yam ntxwv ntawm tus neeg mob lub cev, tseem nyob ruaj khov.

Tsis zoo li kev npaj ua ntej, kev tswj hwm qhov ncauj ntawm qhov kev noj tshuaj ntawm fenofibrate (nanoparticles) tuaj yeem nqa tau txhua lub sijhawm ntawm hnub, tsis hais noj zaub mov, uas hauv qhov no tsis cuam tshuam qhov siab tshaj plaws ntshav ntshav ntawm fenofibrate thiab nws cov nyhuv dav dav.

Tom qab nkag sab hauv fenofibrate tau sai ntawm hydrolysis esterasesnrog ntshav tawm fenofibroic acid (cov khoom siv tshuaj tiv thaiv kab mob loj). Qhov kev sib txuas ruaj khov yog pom nyob rau hauv cov ntshav ntshav fenofibroic acid nrog albumin(ntau dua 99%). T1 / 2 ntawm cov tshuaj metabolite tseem ceeb ntawm cov tshuaj yog kwv yees li 20 teev. Fenofibrate tsis koom nrog microsomal metabolism thiab tsis koom ua ib lub cev rau CYP3A4.

Kev zam ntawm cov tshuaj nrog zis yog nqa tawm tsuas yog nyob rau hauv daim ntawv ntawm fenofibroic acidli qub glucuronide conjugateCov. Rau 6 hnub, yuav luag tiav kev tshem tawm ntawm fenofibrate yog cai.

Tag nrho clearance fenofibroic acid tsis hloov nrog lub hnub nyoog ntawm tus neeg mob. Cumulation ntawm cov tshuaj tsis tshwm sim. Thov hemodialysiskom tshem tawm fenofibrate yog qhov tsis muaj txiaj ntsig.

Ntsiav tshuaj ntawm Tricor 160 mg, nyob rau hauv kev sib piv nrog kev kho ua ntej ntawm fenofibrate, yog tus cwj pwm los ntawm ntau dua bioavailability.

Hauv tib neeg cov ntshav, thawj zaug fenofibrate tsis pom. Lub plasma tseem ceeb khoom ntawm cov tshuaj metabolism hauv yog txiav txim siab fenofibroic acid.

Kev Ntshav Cmax raug pom nyob tom qab 4-5 teev tom qab kev tswj hwm qhov ncauj ntawm cov tshuaj. Kev siv lub sijhawm ntev ntawm fenofibrate tsis ua rau muaj kev hloov pauv hauv nws lub plasma concentration, uas tsis hais tus yam ntxwv ntawm tus neeg mob lub cev, tseem nyob ruaj khov. Qhov nqus ntawm daim ntawv kho no ntawm fenofibrate ntau ntxiv nrog nws cov khoom sib xyaw ua ke nrog zaub mov.

Hauv ntshav, tsuas yog cov khoom tseem ceeb ntawm cov fenofibrate metabolism yog kuaj - fenofibroic aciduas stably khi rau albuminntau dua 99%. T1 / 2 ntawm cov tshuaj metabolite tseem ceeb ntawm cov tshuaj yog kwv yees li 20 teev.

Kev zam ntawm cov tshuaj nrog zis yog nqa tawm tsuas yog nyob rau hauv daim ntawv ntawm fenofibroic acidli qub glucuronide conjugateCov. Rau 6 hnub, yuav luag tiav kev tshem tawm ntawm fenofibrate yog cai.

Tag nrho clearance fenofibroic acid tsis hloov nrog lub hnub nyoog ntawm tus neeg mob. Cumulation ntawm cov tshuaj tsis tshwm sim. Thov hemodialysiskom tshem tawm fenofibrate yog qhov tsis muaj txiaj ntsig.

Kev ntsuas rau siv

Tricor yog qhia rau siv nyob rau hauv thiaj li:

  • kev kho mob cais lossis sib xyaw hypercholesterolemiathiab hypertriglyceridemia(dyslipidemia IIa, IIb, III, IV, V hom) thaum tsis muaj qab hau kev kho kev noj hauslossis lwm txoj hauv kev siv tshuaj tsis raug cai (suav nrog kev poob phaus, nce lub cev kev ua si, thiab lwm yam), tshwj xeeb yog qhov muaj kev pheej hmoo ntxiv cuam tshuam nrog dyslipidemia(haus luam yeeb, leeg ntshav siab),
  • kev kho mob theem nrab hyperlipoproteinemiathaum txuag hyperlipoproteinemiatxawm tias tiv thaiv keeb kwm yav dhau los ntawm kev kho mob ntawm qhov pib pathology (piv txwv li, dyslipidemianyob ntawm mob ntshav qab zib).

Cov Yuav Tsum Muaj

Lub hom phiaj ntawm cov tshuaj Tricor yog contraindicated nyob rau hauv:

  • hnyav daim siab pathologies (suav nrog mob ntsws) lossis raum(nrog QC tsawg dua 20ml / min),
  • tus kheej hypersensitivity rau fenofibratelossis lwm yam tshuaj hauv ncoo,
  • pub niam mis
  • qab zib intolerance,
  • pathologies ntawm lub qog,
  • keeb kwm ntawm tus neeg mob phototoxicitylossis photosensitizationnrog kev tau txais txiaj ntsig yav dhau los ntawm fibrates lossis Ketoprofen,
  • yav dhau los kev fab tshuaj tsis haum nyob taum Lecithin, txiv laum huab xeeblos yog nws cov roj, nrog rau cov zaub mov uas muaj feem xyuam (muaj kev phom sij rau lub siab ntsws),
  • hnub nyoog txog 18 xyoo.

Tricor tau siv nrog nrog ceeb toom ceev thaum:

  • tsis ua hauj lwm hepatic/lub raumhaujlwm
  • quav cawv,
  • hypothyroidism,
  • burdened keeb kwm ntawm muaj keeb cov leeg pathologies,
  • parallel txais tos statins,
  • thaum laus.

Tricor, cov lus qhia rau kev siv (qauv thiab npaum li cas)

Cov ntsiav tshuaj ntawm cov tshuaj Tricor yog npaj rau qhov ncauj tswj hwm hauv txhua daim ntawv ua ke nrog dej (200-250 ml). Cov lus qhia siv Tricor 145 mg tso cai rau kev tswj hwm ntawm cov ntsiav tshuaj ntawm cov tshuaj, tsis hais txog zaub mov noj, txhua lub sijhawm yooj yim rau tus neeg mob. Tricor 160 mg ntsiav tshuaj yuav tsum noj nrog pluas noj.

Qhov tshuaj ntau npaum li cas ntawm kev kho mob nrog Tricor cuam tshuam kev noj ib hnub los ntawm cov neeg laus ntawm ib ntsiav tshuaj ntawm 145 mg lossis 160 mg. Cov ntaub ntawv ntau npaum ntawm Traicor, nrog rau kev npaj ua ntej nrog kev fenofibrate ntawm 200 mg (piv txwv, Lipantil 200 M) suav tias yog sib npaug, hauv kev txuas nrog qhov twg, kev hloov los ntawm kev noj ib hom tshuaj rau lwm tus yog ua tiav yam tsis muaj kev kho ntau npaum li cas.

Cov neeg mob uas lub raum tsis zoo lub ntsws yuav tsum tau kho nrog kev noj tshuaj tsawg dua. Cov neeg laus yog cov tsis xav tau kev hloov kho koob. Kev siv Tricor rau kev kho mob ntawm cov neeg mob nrogdaim siab pathologies tsis kawm ntawv.

Kev Kho Mob nrog Tricor yuav tsum tau nqa tawm rau ib lub sijhawm ntev, hauv parallel nrog kev noj haussau ntawv rau tus neeg mob ua ntej pib kev kho mob. Tus kws kho mob uas tuaj koom yuav tsum ntsuas ntsuas ua haujlwm zoo ntawm kev kho. Cov qauv rau kev ntsuam xyuas no yog cov ntsiab lus ntsuas dej lipids(suav nrog tag nrho cov roj (cholesterol), triglyceridesthiab LDL) Yog tias tsis muaj kev kho mob tom qab ob peb lub hlis (feem ntau tom qab 3 lub hlis) ntawm kev noj cov tshuaj Tricor, cov lus nug ntawm qhov tsim nyog ntawm nws siv txuas ntxiv thiab tseem muaj kev kho mob ntxiv yuav tsum tau soj ntsuam.

Kev sib txuam

Concurrent siv fenofibrate nrog lub qhov ncauj tshuaj thaiv tsevua rau muaj kev nce ntxiv hauv lawv cov txiaj ntsig thiab, vim li ntawd, ua rau muaj kev pheej hmoo ntxiv los ntshavvim yog neeg coob dhau anticoagulantlos ntawm cov khi nyiaj protein. Thaum pib kho fenofibratepom zoo kom txo qhov ntau npaum li cas los ntawm tus neeg mob tshuaj thaiv tsevtxog thib peb, nrog ntxiv xaiv cov koob tshuaj kom haum rau lawv. Tsuas tshuaj anticoagulantxaiv nyob rau hauv raws li theem ntawm INR.

Nrog kev siv sib koom tes ntawm fenofibrate thiab Cyclosporin ob peb lub sijhawm rov tshwm sim hnyav heev tau pom ua rau lub raum tsis zooCov. Cov tshuaj sib xyaw no yuav tsum tau soj ntsuam lub xeev ntawm lub raum kev ua haujlwm thiab lub sijhawm tshem tawm ntawm fenofibrate thaum muaj kev pauv hloov tseem ceeb hauv chav ntsuas.

Kev siv ua ke ntawm fenofibrate nrog rau lwm cov fibrates lossis statins ua rau kom muaj kev phom sij zoo hauv kev cuam tshuam txog cov leeg nqaij.

Kev Tshawb Fawb microsomestib neeg lub siab (hauv vitro) qhia qhov tsis muaj ntawm cov nyhuv inhibitory ntawm fenofibrate thiab nws lub ntsiab ntawm cov metabolite - fenofibroic acid ntawm isoenzymes cytochrome P450: CYP2D6, CYP1A2, CYP3A4, CYP2E1B, nrog rau qhov ua kom tsis muaj zog ntawm cov isoenzymes CYP2C19 thiab CYP2A6 thiab mob siab rau CYP2C9.

Cov lus qhia tshwj xeeb

Khaws Tricor mob ntshav qab zib Hom 2 cov tsos mob nephrotic, hypothyroidism, dysproteinemia, qhov cuam tshuam tsis zoo ntawm kev kho tshuaj, cuam tshuamdaim siab pathologies, quav cawv thiab lwm yam mob uas zoo sib xws, nws muaj peev xwm ua tau tsuas yog tom qab kev kho mob ua ntej tsom mus rau tshem tawm lwm yam ua ob hypercholesterolemia.

Tus kws kho mob uas tuaj koom yuav tsum ntsuas ntsuas ua haujlwm zoo ntawm kev kho. Cov qauv rau kev ntsuam xyuas no yog cov ntsiab lus ntsuas dej lipids (suav nrog tag nrho cov roj (cholesterol), triglyceridesthiab LDL) Yog tias tsis muaj kev kho mob tom qab ob peb lub hlis (feem ntau tom qab 3 lub hlis) ntawm kev noj cov tshuaj Tricor, cov lus nug ntawm qhov tsim nyog ntawm nws siv txuas ntxiv thiab tseem muaj kev kho mob ntxiv yuav tsum tau soj ntsuam.

Hauv cov neeg mob nrog hyperlipidemiakev kho mob nrog tshuaj estrogen lossis tswj tuav qhov ncauj tshuaj tiv thaiv hormonalsuav nrog estrogens, yuav tsum txiav txim siab qhov tsim ua thawj lossis theem nrab ntawm kev tsim hyperlipidemiatxij li ntawm nce qib hauv qib lipidstej zaum vim muaj kev txais tos tshuaj estrogen.

Tawm tsam keeb kwm yav dhau los ntawm kev siv ntawm Traicor thiab lwm yam kev kho mob kom txo cov qib ntawm lipids, Qee zaum pom muaj nce hauv cov ntsiab lus hepatic transaminasesCov. Feem ntau, qhov nce ntxiv yog ib ntus, tsis tseem ceeb thiab muaj asymptomatic. Hauv thawj 12 lub hlis ntawm kev kho, Triicor pom zoo kom soj ntsuam cov tshuaj tsi ntsees transaminase(AST, ALT) txhua txhua 3 lub hlis. Yog tias tus neeg mob tau nce qib siab transaminasenws yog qhov yuav tsum tau ua tib zoo saib xyuas nws cov xwm txheej ntxiv thiab, nrog kev nce ntxiv ntawm cov ntsiab lus ntawm AST thiab ALT los ntawm qhov muaj peb ntawm kev sib piv nrog VGN, tsum tsis txhob noj Traicor.

Thaum kho, kev mob tshwm sim los ntawm Tricor tau piav qhia. pancreatitisCov. Qhov tshwm sim muaj feem ntawm cov kab mob pathology hauv no yog: qhov ua tsis tau zoo ntawm kev kho mob hauv cov neeg mob uas mob hnyav hypertriglyceridemia, qhov cuam tshuam ncaj qha ntawm txoj kev daws nws tus kheej, nrog rau lwm yam kev cuam tshuam cuam tshuam nrog lub xub ntiag ntawm lub qog los yog qhov tsim los ntawm kev ziab hauv nws, nrog los ntawm kev khaum ntawm hom bile duct.

Kev siv Tricor, zoo li lwm yam tshuaj uas txo cov ntsiab lus lipids, tuaj yeem ua rau mob lom rau cov leeg nqaij, mus txog ntawm kev txhim kho rhabdomyolysis(muaj tsawg zaus). Qhov ntau zaus ntawm cov xwm txheej zoo li no nce ntxiv thaum tus neeg mob muaj keeb kwm ntawm lub raum tsis ua hauj lwm thiab hypoalbuminemiaCov. Kev xoom xaim ntawm kev siv tshuaj lom rau cov tshuaj ntawm cov nqaij ntshiv yog qhov tsim nyog nyob rau hauv rooj plaub ntawm tus neeg mob tsis txaus siab mob mob vwmtsis muaj zog mob leeg thiab cramping, diffuse myalgia, nrog rau kev cim sau hauv kev ua si kev tsim tawm phosphokinase(tsib zaug dua VGN). Hauv cov rooj plaub no, kev kho nrog Tricor yuav tsum tsis ua mus ntxiv.

Raug teeb meem rhabdomyolysisnce nyob rau hauv cov neeg mob predisposed rau rhabdomyolysisthiab / lossis myopathiessuav nrog cov hnub nyoog laus dua (laus dua 70 xyoo), haus cawvburdened los ntawm keeb kwm muaj keeb ntawm cov kab mob leeg, hypothyroidism, tsis hnov ​​mob raum muaj nuj nqiCov. Cov neeg mob ntawm cov pab pawg no tuaj yeem raug sau Tricor tsuas yog muaj qhov cuam tshuam loj heev ntawm cov txiaj ntsig ntawm kev kho mob piv rau cov kev pheej hmoo tsim kho rhabdomyolysis.

Kev siv ua ke ntawm fenofibrate nrog rau lwm cov fibrates lossis statins ua rau muaj qhov mob hnyav ntxiv lom cuam tshuam nyob rau hauv kev sib txuas nrog cov leeg nqaij, tshwj xeeb nrog yav dhau los mob kab mobCov. Vim li no, kev kho kom haum nrog Tricor thiab statinstsuas yog hais tias tus neeg mob tau sib xyaw lawm dyslipidemiamuaj mob loj thiab muaj qhov pheej hmoo kev mob plawv, thaum tsis muaj nws lub keeb kwm mob kab mobthiab nyob rau hauv qhov xwm txheej ntawm kev saib xyuas tas li ntawm kev phiv tshuaj lom rau cov leeg nqaij.

Thaum theem nce qib neeg tsim tswvntau dua ib zaug thiab siab dua VGN, kev kho nrog Trikor yuav tsum nres. Thawj 3 lub hlis ntawm kev kho, cov tshuaj muaj tswv yim muaj zog yuav tsum raug tshuaj xyuas tsis tseg.

Tso tawm daim ntawv thiab muaj pes tsawg leeg

Daim ntawv ntau npaum li cas ntawm kev tso tawm Traicor yog cov ntsiav tshuaj zaj duab xis: oblong, dawb, daim ntawv sau "145" lossis "160" ntawm ib sab (nyob ntawm seb ntau npaum li cas), nyob rau lwm qhov - lub tuam txhab logo (hauv cov hlwv ntawm 10 pcs., Nyob hauv ib daim ntawv qhia cardboard 1 –5, 9 lossis 10 lub hlwv, hauv lub hlwv ntawm 14 pcs., Hauv daim duab tuab ntawm daim npav 2, 6 lossis 7 hlwv).

Composition 1 ntsiav tshuaj:

  • cov tshuaj nquag: fenofibrate - 145 (micronized) lossis 160 mg,
  • kev tshem tawm (145/160 mg): sucrose - 145/0 mg, sodium lauryl sulfate - 10.2 / 5.6 mg, lactose monohydrate - 132 / 138.4 mg, crospovidone - 75.5 / 96 mg, microcrystalline cellulose - 84.28 / 115 mg, colloidal silicon dioxide - 1.72 / 12.6 mg, hypromellose - 29/0 mg, docusate sodium - 2.9 / 0 mg, magnesium stearate - 0.9 / 0 mg, sodium stearyl fumarate - 0 / 6.4 mg, povidone - 0/160 mg,
  • plhaub (145/160 mg): opadry OY-B-28920 (titanium dioxide - 8.03 / 8.96 mg, polyvinyl cawv - 11.43 / 12.75 mg, soya lecithin - 0.5 / 0.56 mg) , talc - 5.02 / 5.6 mg, xanthan ntawm cov pos hniav - 0.12 / 0.13 mg) - 25.1 / 28 mg.

Cov Tshuaj Pharmacokinetics

Hauv ntshav, qhov pib fenofibrate tsis pom. Lub ntsiab plasma metabolite yog fenofibroic acid.

Qhov siab tshaj plaws ntawm ib yam khoom hauv ntshav ntshav yog ua tiav tom qab 2–4 teev (145 mg txhua) lossis 4-5 teev (160 mg ib qho) tom qab kev tswj hwm ntawm Tricor. Lub plasma concentration ntawm cov tshuaj thaum lub sij hawm ntev kawm tseem ruaj khov thiab tsis nyob ntawm tus kheej cov yam ntxwv ntawm tus neeg mob.

Cov lus sib xyaw ntawm Tricor hauv 145 mg suav nrog micronized fenofibrate nyob rau hauv daim ntawv ntawm nanoparticles. Qhov sib txawv ntawm daim ntawv tso tawm no los ntawm kev txiav txim ntau dhau los ntawm fenofibrate yog lub siab tshaj plaws nyob rau hauv ntshav thiab qhov dav dav ntawm fenofibrate nyob rau hauv daim ntawv ntawm nanoparticles. Qhov ua tau zoo ntawm cov tshuaj tsis yog nyob ntawm kev noj zaub mov, thiab yog li nws tuaj yeem siv tsis hais txog kev noj zaub mov thaum lub sijhawm twg los tau.

Qhov nqus ntawm fenofibrate thaum ua ntawv thov Tricor 160 mg yog txhim kho thaum noj nrog zaub mov.

Ntau tshaj li 99% ntawm fenofibroic acid yog khov kho ua cov plasma albumin.

Ib nrab-lub neej ntawm fenofibroic acid yog kwv yees li 20 teev.

Fenofibrate tom qab kev tswj hwm ntawm qhov ncauj tau nrawm nrawm dua los ntawm esterases. Tsuas yog nws cov khoom noj tseem ceeb metabolite, fenofibroic acid, muaj nyob hauv cov ntshav.

Fenofibrate tsis yog qhov khoom pov tseg rau CYP3A4. Hauv microsomal metabolism tsis koom nrog.

Kev nqhis dej feem ntau tshwm sim nrog zis hauv daim ntawv ntawm kev txuas ntawm glucuronide thiab fenofibroic acid. Fenofibrate yog tshem tawm yuav luag txhua yam hauv 6 hnub.

Tom qab txhaj ib koob thiab thaum lub sij hawm ntev kawm, cov tshuaj tsis cumulate.

Nrog hemodialysis, nws tsis raug tawm los.

Cov lus qhia rau kev siv

Tricor yog tus sawv cev lipid-txo qis. Lub hauv paus ntawm cov tshuaj yog fenofibrate, ib yam khoom uas zwm rau pawg neeg derivatives ntawm fibroic acid. Muaj cov qauv hauv cov ntsiav tshuaj rau kev tswj hwm qhov ncauj.

Dragees ntawm cov xim dawb, oblong, muaj kev pheej hmoo nrog ib qho thiab daim ntawv thov logo ntawm lub tuam txhab ntawm lwm tes. Cov khoom lag luam muag khoom hauv ntau cov tshuaj: 145 mg lossis 160 mg. Lawv siv rau kev pom zoo ntawm kws kho mob tom qab dhau kev paub tseeb.

Kev noj Traicor pab txo qis cov triglycerides hauv cov ntshav. Cov tshuaj yog tshuaj kom txo VLDL, LDL, ntxiv rau nce antiatherogenic HDL.

Txawm hais tias kev siv tshuaj ntau nyob rau hauv cov tshuaj, lub hauv paus ntsiab lus ntawm kev txiav txim ntawm fenofibrate tseem tsis tau kawm tag nrho.

Qhov kev ua tau zoo ntawm kev npaj raws li nws yog txiav txim siab los ntawm kev ua kom lub enzyme lipoprotein lipase, nrog rau kev muaj peev xwm ua kom qeeb ntawm cov tshuaj lom ntawm fatty acids. Cov tshuaj nquag ntawm Tricor txhawb kev nce ntawm LDL receptors hauv lub siab ua haujlwm. Kev sib tov ntawm cov roj ua rau qeeb qeeb. Hauv cov neeg mob uas mob ntshav qab zib mellitus tom qab kev tswj hwm, txo qis hauv cov piam thaj hauv ntshav tau pom tias.

Tricor yog kho rau cov neeg mob uas lub plawv tsis ua haujlwm, cov neeg mob uas muaj cov kab mob hauv qab no:

  • hyperlipoproteinemia ntawm hom IIa, IIb, III thiab IV,
  • hypercholesterolemia,
  • hypertriglyceridemia, yog tias kev noj zaub mov ua ke los ntawm tus kws kho mob tsis tau pab tswj cov roj cholesterol kom zoo thiab nws tsis tuaj yeem hloov kho qhov tsis tau yam tsis muaj tshuaj kho.

Koj tuaj yeem yuav cov tshuaj hauv chaw muag tshuaj ntawm tus nqi ntawm 700 rubles. mus txog 900 rub. rau kev ntim khoom.

Hauv tsev

Cov lus piv txwv Lavxias ntawm cov tshuaj Tricor yog Fenofibrat Canon. Koj tuaj yeem nrhiav cov lus zoo nyob rau yuav luag txhua lub tsev muag tshuaj ntawm tus nqi pheej yig. Tus nqi nruab nrab tsis tshaj 400 rubles., Ntawm tus nqi Tricor los ntawm 800-850 rubles. thiab.

Fenofibrate Canon muaj nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj rau kev tswj hwm qhov ncauj ntau npaum ntawm 145 mg coated. Tus nqi nruab nrab ntawm no kab ntawm Traicor yog 500 p.

Ntim: ntim - 30 ntsiav tshuaj. Cov tshuaj yeeb dej caw yog fenofibrate (zoo ib yam li qhov qub).

Thov rau cov kev ua txhaum hauv qab no:

  • kab mob ntawm cov hlab plawv system,
  • hyperlipoproteinemia ntawm hom IIa, IIb, III, IV,
  • hypercholesterolemia,
  • hypertriglyceridemia.

Tsis muaj qhov sib txawv hauv qhov txheej txheem ntawm kev txais tos. Kev qhia rau kev siv yog tib yam li nrog tshuaj Tricor.

Txawv teb chaws hloov chaw ntawm Tricor, uas muaj cov nyhuv zoo ntawm lub cev: Lipantil 200 M, Lofat, zoo li Nofibal.

Tsuas yog tus kws kho mob uas tuaj koom yuav tsum xaiv txoj kev kho zoo rau kev kho mob.

Lipantil 200 M

Lipantil 200 M muaj nyob rau hauv Lavxias thiab Fabkis. Daim ntawv muag khoom: 200 mg tsiav tshuaj. Lawv tus nqi qis dua li tus nqi Tricor.

Hauv cov khw muag tshuaj Lipantil 200 M, nws raug muag rau 700-750 rubles. rau ib pob, txhua tus muaj 30 daim duab ntxig tau tsaj, hnav nrog txheej pleev xim dawb.

Cov tshuaj nquag, zoo ib yam li nrog rau cov tshuaj dhau los, yog fenofibrate. Nws qhov ntau npaum li cas hauv ib lub tshuaj ntsiav, tsim rau ib koob yog siab dua qhov ntawm Traicor.

Ua ntej siv, ua tib zoo nyeem cov lus qhia thiab teev tus lej txhua hnub uas tus kws kho mob xav tau. Cov tshuaj muaj hnub nyoog txwv rau cov neeg mob.

Ib qho ntxiv ntawm Traicore tsim nyob rau Fabkis yog Lofat. Cov tshuaj uas ua rau kho cov nyhuv yog fenofibrate. Cov tshuaj muag yog muag hauv tsab ntawv ntawm enteric-coated capsulesCov. Tsuas tshuaj - 250 mg. Ib tug lipid-txo tus neeg sawv cev siv rau tib tus naj npawb ntawm cov kab mob zoo li cov tshuaj dhau los. Cov nqi muag khoom ntawm Lofat yog li 600 rubles. Tam sim no tsis muaj nyob hauv cov chaw muag tshuaj.

Nofibal yog ib tus neeg sawv cev hypolipidemic nyob rau hauv daim ntawv tshuaj ntsiav. Tsim raws fenofibrate. Qhov kev txiav txim siab ntawm kev txais tos yog zoo ib yam rau analogues.

  • hypercholesterolemia (hom IIa),
  • endogenous hypertriglyceridemia (hom IV),
  • hypercholesterolemia.

Cov tshuaj yuav tau rov sau npe thiab tam sim no tsis muaj nyob hauv cov chaw muag tshuaj.

Nofibal tau muab tshuaj los ntawm kws kho mob thaum endogenous hypertriglyceridemia tau kuaj. Cov tshuaj tau raug muab coj los ua ke nrog kev noj haus thiab kev tawm dag zog tshwj xeeb. Koj yuav tsum haus tshuaj ntawm 400 ml ib hnub twg.

Txawm hais tias qhov siab npaum li cas, tsis muaj kev phiv, nws yog zoo zam. Thaum pib, kev mob tshwm sim hauv cov lus qhia tau ceeb toom. Koj tuaj yeem txiav txim siab qhov ua tau zoo ntawm kev soj ntsuam.

Lipantil 200 M yog tshuaj zoo. Raug xaiv los kho cov roj ntsha, txo cov roj cholesterol. Qhov xwm txheej tau nyuaj los ntawm kev hnyav dhau thiab tawg. Cov pluas noj uas muaj zaub mov muaj txiaj ntsig zoo, kev pom zoo noj tsis tau pab lawm, zoo li lwm tus kws kho mob pom zoo.

Kuv yuav tsum tau mus rau cov chaw muag tshuaj. Tus kws kho mob tau sau tseg qhov tshwm sim tom qab ua tiav qhov kev kawm. Cholesterol tsawg. Tsis tas li ntawd, qhov hnyav tau poob qis thiab o tau ploj mus. Cov tshuaj ntsiav muaj lub zog me me, yog li lawv tuaj yeem yooj yim rau kev noj. Koj yuav tsum haus ib hnub ib zaug.

Nqi hauv cov chaw muag tshuaj

Cov ntaub ntawv hais txog tus nqi Tricor hauv cov khw muag tshuaj hauv Lavxias yog coj los ntawm cov ntaub ntawv ntawm cov khw muag tshuaj online thiab kuj yuav txawv me ntsis ntawm tus nqi hauv koj thaj av.

Koj tuaj yeem yuav cov tshuaj hauv Moscow cov khw muag tshuaj ntawm tus nqi: Tricor 145mg 30 ntsiav tshuaj - los ntawm 834 txog 845 rubles.

Qhov xwm txheej ntawm kev faib tawm los ntawm cov khw muag tshuaj yog los ntawm cov tshuaj noj.

Khaws rau hauv qhov chaw qhuav ntawm qhov kub txog 25 ° C. Khaws tsis ncav cuag ntawm cov menyuam yaus.

Cov npe ntawm cov analogues tau nthuav tawm hauv qab no.

Dab tsi pab kom Tricor 145 thiab 160 mg?

Lub tshuaj Tricor yog tshuaj rau hauv cov teebmeem hauv qab no:

  • Hypercholesterolemia thiab hypertriglyceridemia cais los yog sib xyaw (dyslipidemia type iia, iib, III, IV, V) (tab. 145 mg) thiab (dyslipidemia type iia, iib, III, IV, V) (tab. 160 mg) hauv cov neeg mob rau tus neeg mob kev noj zaub mov noj lossis lwm yam kev ntsuas tshuaj tsis zoo (piv txwv li kev poob phaus lossis lub cev ua kom lub cev ntau ntxiv) tau ua haujlwm tsis muaj txiaj ntsig, tshwj xeeb yog muaj kev pheej hmoo cuam tshuam nrog kev ua txhaum kabmob, xws li kub siab thiab haus luam yeeb,
  • Thib ob hyperlipoproteinemia nyob rau hauv cov mob uas hyperlipoproteinemia mob tsawv txawm hais tias muaj kev kho mob tseem ceeb ntawm tus mob tseem ceeb (piv txwv li, dyslipidemia nyob rau hauv ntshav qab zib mellitus).

Thaum siv cov tshuaj yuav tsum ua raws li kev noj haus.

Sab Sij Huam ntawm Tricor

Cov lus qhia rau kev siv ceeb toom ntawm kev muaj peev xwm los tsim kev phiv los ntawm cov tshuaj Tricor:

    Los ntawm cov khoom siv rau lub plab zom mov: (> 1/100, 1/1000, 1/10 000, 1/1000, 1/10 000, 1/10 000, 1/1000, 1/1000, Kev Tiv Thaiv Txhaum Cai)

Nws yog contraindicated yuav siv Tricor 145 hauv kab mob lossis kab mob hauv qab no:

  • ua kom lub ntsej muag tsis haum fenofibrate lossis lwm yam tshuaj,
  • mob rau daim siab hnyav (suav nrog mob ntsws),
  • mob raum tsis ua haujlwm (Cl creatinine overdose)

Cov dej cawv ntawm kev siv tshuaj ntau dhau tsis tau sau npe, txawm li cas los xij, kom tsis txhob muaj kev phiv tshuaj tsis zoo, nws tsis raug pom zoo kom tshaj li cov koob tshuaj tau qhia hauv cov lus qhia.

Thaum raug mob los ntawm kev siv ntau cov ntsiav tshuaj, nws raug nquahu kom tsis txhob ntuav, yog tias tsim nyog, yaug lub plab thiab muab cov ntsiav tshuaj enterosorbent.

Sau cov analogues ntawm Tricor

Yog tias tsim nyog, hloov cov tshuaj, ob txoj kev xaiv yog muaj peev xwm - kev xaiv ntawm lwm cov tshuaj nrog tib cov tshuaj nquag lossis cov tshuaj uas muaj cov nyhuv zoo sib xws, tab sis nrog lwm cov tshuaj ntxiv.

Cov tshuaj ntawm Tricor 145, ib daim ntawv teev tshuaj:

  1. Lipantil 200 M,
  2. Fenofibrat Canon
  3. Tshaj.

Zoo tshuaj:

Thaum xaiv ib qho hloov tshiab nws yog qhov tseem ceeb kom nkag siab tias tus nqi, cov lus qhia rau kev siv thiab tshuaj xyuas ntawm Tricor 145 tsis siv rau analogues. Ua ntej hloov, nws yog qhov yuav tsum tau txais kev pom zoo los ntawm tus kws kho mob tuaj koom thiab tsis yog los hloov cov tshuaj ntawm nws tus kheej.

Kev tshuaj xyuas txog Tricor 145 mg yog ob peb thiab tsis meej xwm. Qee tus kws kho mob yuav ua tiav siv nws los ua qhov tsis txaus siab lipid profile ntawm lawv cov neeg mob, saib qhov ua tau zoo ntawm cov tshuaj no thiab txaus siab rau qhov tshwm sim ntawm kev kho nrog nws siv. Lwm tus kws tshaj lij kho qhov kev nqis tes ntawm Traicor nrog kev ceev faj thiab nco ntsoov tias qhov tshwm sim tsis zoo ntawm cov tshuaj (pob zeb tsim, rhabdomyolysis, photosensitization) kov yeej nws cov peev txheej zoo.

Cov Ntaub Ntawv Tshwj Xeeb rau Cov Kws Khomob

Kev sib txuam

Kev siv tib lub fenofibrate nrog lub qhov ncauj anticoagulants ua rau muaj kev nce ntxiv hauv lawv cov txiaj ntsig thiab, vim li no, ua rau muaj kev pheej hmoo ntxiv los ntshav vim los ntawm kev tshem tawm ntawm cov tshuaj anticoagulant los ntawm cov protein. Thaum pib ntawm fenofibrate txoj kev kho, nws raug nquahu tias ntau npaum li cas ntawm cov tshuaj tiv thaiv anticoagulants los ntawm tus neeg mob txo los ntawm ib feem peb, nrog ntxiv xaiv cov hom phiaj ntawm lawv cov koob tshuaj uas tsim nyog. Cov koob tshuaj ntawm cov tshuaj thaiv tsev yog xaiv raws qib ntawm INR.

Nrog rau kev siv ua ke ntawm fenofibrate thiab cyclosporin, ob peb ntu kev tshwm sim ntawm kev thim rov qab hauv lub raum muaj nuj nqi tau sau tseg. Cov tshuaj sib xyaw no yuav tsum tau soj ntsuam lub xeev ntawm lub raum kev ua haujlwm thiab lub sijhawm tshem tawm ntawm fenofibrate thaum muaj kev pauv hloov tseem ceeb hauv chav ntsuas.

Kev siv ua ke ntawm fenofibrate nrog rau lwm cov fibrates lossis statins ua rau kom muaj kev phom sij zoo hauv kev cuam tshuam txog cov leeg nqaij.

Kev tshawb nrhiav ntawm tib neeg lub siab microsomes (hauv vitro) qhia txog qhov tsis muaj qhov cuam tshuam ntawm fenofibrate thiab nws lub ntsiab metabolite, fenofibroic acid, ntawm P450 cytochrome isoenzymes: CYP2D6, CYP1A2, CYP3A4, CYP2E1B, zoo li lub zog cuam tshuam rau CYP2 thiab CYP2

Cov lus qhia tshwj xeeb

Txoj kev kho yuav tsum tau ua nrog kev sib xyaw nrog kev noj zaub mov zoo thiab nyob hauv kev saib xyuas ntawm tus kws kho mob.

Thaum tsis muaj qhov ua tau zoo txaus siab tom qab 3-6 lub hlis ntawm kev tswj hwm, concomitant lossis lwm txoj kev kho tuaj yeem raug kho.

Nws raug nquahu kom soj ntsuam cov haujlwm ntawm "hepatic" hloov pauv txhua 3 lub hlis nyob rau thawj xyoo ntawm kev kho, kev so ib ntus hauv kev kho yog tias lawv cov haujlwm nce ntxiv, thiab tsis suav nrog kev kho mob ib yam li cov tshuaj hepatotoxic.

Tus neeg sawv cev Hypolipidemic Tricor: cov lus qhia rau kev siv, tus nqi, tshuaj xyuas thiab cov tshuaj ntawm cov tshuaj

Qhov ncauj ntsiav tshuaj Tricor ob qho tib si 145 thiab 160 mg muaj yam tshuaj nquag nyob rau hauv daim ntawv ntawm fenofibrate.

Raws li rau qhov kev txiav txim ntawm pharmacological, nws yog lipid-txo qis (los yog qis dua cov concentration ntawm lipids). Cov tshuaj belongs rau lub pharmacological pab pawg ntawm cov fibrates.

Tus yam ntxwv dav

Yeej, cov tshuaj yog siv rau pathologies uas cuam tshuam nrog:

  • nrog ob qho insulin-dependant thiab tsis-insulin-cuam tshuam kev mob ntshav qab zib mellitus,
  • nrog hypercholesterolemia (cov roj ntsha hauv ntshav), hyperglyceridemia (ntau triglycerides),
  • nrog kev sib xyaw hyperlipidemia (ntshav siab ntawm ob cov roj thiab rog, thiab triglyceride),
  • ntxiv rau nrog rau lwm cov hyperlipidemia.

Hais txog hyperlipidemia, peb tuaj yeem hais tias lawv yog qhov kev hem thawj rau lub plawv thiab cov hlab ntsha thiab qhov tseem ceeb ua rau tuag, piv txwv, hauv ib lub tebchaws xws li Tebchaws Asmeskas.

Raws li rau cov ntaub ntawv hais txog kev ua tswv cuab ntawm Tricor hauv ib pab pawg saib xyuas thiab chaw muag tshuaj, cov chaw tsim khoom cov lus qhia Recipharm Monts, ntxiv rau Laboratoies Fournier S.A. nws tsuas yog tsis tuaj.

Pharmacological kev ua thiab kev ntsuas

Thaum lub sijhawm sim cov tshuaj Tricor ncaj qha rau hauv cov chaw kho mob, kev tshawb fawb ntawm cov neeg mob tau qhia tias nrog kev pab ntawm fenofibrate, qib ntawm cov roj (cholesterol) hauv cov neeg mob tsawg dua 20, lossis tseem txog 25%, thiab kev xav txog qhov txo qis qis lawv cov roj triglycerides, qhov ntsuas no yog los ntawm 40 thiab nce mus txog 55%.

Ntsiav tshuaj Tricor 145 mg

Ntxiv mus, hauv cov neeg mob hypercholesterolemia, tus piv ntawm tag nrho thiab LDL cov cholesterol tsawg dua. Nws yuav tsum tau yug hauv siab tias qhov kev sib piv no yog ib qho kev txiav txim siab ntawm txoj kev pheej hmoo ntxiv ntawm cov kab mob plawv.

TshuajNws yog qhov qhia ntxiv rau txoj hauv kev tsis siv tshuaj kho mob. Txawv xws li ntau yam kev tawm dag zog lub cev, cov txheej txheem ntawm kev poob phaus, nrog rau kev siv zaub mov noj rau cov kab mob:

  • hypertriglycemia,
  • sib xyaw hyperlipidemia, yog tias muaj cov lus sib tshooj rau statins (tshuaj uas txo cov roj cholesterol),
  • sib xyaw hyperlipidimia. Thaum tus neeg mob muaj kev pheej hmoo siab ntawm ob leeg mob plawv thiab leeg ntshav khiav mus los,
  • thiab cov ntsiav tshuaj tau sau tseg rau hauv cov kab mob ntshav qab zib hauv rooj plaub thaum kev noj zaub mov thiab lub cev ua haujlwm tsis zoo.

Fenofibrate yog ib yam khoom uas ua los ntawm fibric acid. Nws hloov pauv qhov sib piv ntawm cov lipids hauv cov ntshav.

Thaum kho, cov kev hloov hauv qab no yog hais tseg:

  • ntxiv kev ntshiab lossis ntshav ua kom huv,
  • hauv cov neeg mob uas muaj kev pheej hmoo mob plawv, cov qib ntawm atherogenic lipoproteins tsawg (qhov sib piv, uas ua rau kom muaj kev pheej hmoo ntawm atherosclerosis) lossis "tsis zoo" cov roj (cholesterol),
  • pab txhim kho cov roj "kom zoo",
  • kev muaj peev xwm nkag mus rau hauv intravascular deposit yog ho txo,
  • qib ntawm fibriogen yog txo,
  • cov ntshav txo cov ntsiab lus ntawm uric acid, ntxiv rau cov protein C-reactive kev ua hauv nws cov ntshav.

Cov ntsiab lus siab tshaj plaws ntawm fenofibrate hauv cov ntshav tshwm sim hauv ob peb teev tom qab noj tus neeg mob Tricor.

Txawm hais tias muaj kev kho mob ntev nrog kev siv tshuaj kho mob, qhov no tsis ua rau nws cov kev txuam nrog hauv lub cev.

Nws yog kiag li tawm tsis pub dhau 6-7 hnub tsuas yog nrog zis. Nyob rau tib lub sijhawm, fenofibrate tsis raug tawm thaum lub sij hawm hemodialysis, txij li nws hloov tawm kom khov kho rau cov plasma albumin (cov protein tseem ceeb).

Cev xeeb tub

Raws li kev paub txog kev sim tshuaj thiab nyob hauv tus txheej txheem ntawm kev siv tshuaj los ntawm cov poj niam cev xeeb tub, nws tsis txaus.

Piv txwv li, hauv kev sim nrog cov tsiaj, cov nyhuv tetratogenic (hnov qab kev loj hlob embryo nyob hauv qab ntawm tshuaj) tsis pom.

Hauv kev ua haujlwm ntawm kev sim ua ntej, embryotoxicity tau tshwm sim los ntawm qhov kev siv ntawm ib qho ntawm tus poj niam cev xeeb tub nrog qhov loj ntawm cov tshuaj. Txawm li cas los xij, kev pheej hmoo rau cov poj niam cev xeeb tub tseem tsis tau txiav txim siab tag nrho.

Cov tshuaj Tricor yuav tsum tau teem rau cov poj niam cev xeeb tub tom qab ntsuas ob qho txiaj ntsig thiab kev pheej hmoo.

Teev thiab Hnub

Tseem ceeb kom paub! Cov teeb meem uas muaj suab thaj ntau ntau hauv lub sijhawm tuaj yeem ua rau tag nrho cov kab mob, xws li teeb meem tsis pom kev, tawv nqaij thiab plaub hau, mob qog, mob caj pas thiab txawm tias mob qog nqaij hlav! Cov neeg qhia kev iab siab rau normalize lawv qab zib kom txaus siab ...

Cov tshuaj tau noj ntawm qhov ncauj, thaum ntxuav cov ntsiav tshuaj nrog dej. Lub sij hawm kom tsawg nws yog arbitrary thiab tsis yog nyob ntawm cov pluas noj (Tricor 145). Txais tos ntawm Tricorr 160 yuav tsum tau nqa tawm ib txhij nrog cov zaub mov.

Qhov muab tshuaj rau cov neeg mob yog 1 ntsiav tshuaj ib hnub.

Ntxiv mus, yog tias cov neeg mob yav dhau los noj ib ntsiav tshuaj ntawm 160 milligrams ntawm Tricor, tom qab ntawd lawv tuaj yeem, yog tias tsim nyog, hloov mus rau kev noj 145 milligrams ntawm cov tshuaj, thiab tsis tas yuav tau kho dua. Cov neeg mob hauv lub hnub nyoog laus dua yuav tsum noj cov tshuaj - tsis pub ntau dua 1 ntsiav tshuaj ib hnub ib zaug.

Cov nyhuv ntawm cov tshuaj rau cov kab mob ntawm ob lub raum thiab lub siab tsis tau kawm. Txawm hais tias cov kev txheeb xyuas hauv cov ntaub ntawv no tsis sib xws. Yog li no, Taykor yuav tsum ua los ntawm cov neeg mob zoo li no nrog ceev faj.

Cov tshuaj muaj lub sijhawm ntev ntawm kev siv, thaum koj yuav tsum ua raws li cov khoom noj uas tau hais tseg rau yav dhau los. Kev ntsuas qhov ua tau zoo ntawm Tricoror txoj kev kho yuav tsum tau nqa tawm tsuas yog los ntawm tus kws kho mob koom thaum lub sijhawm tshuaj xyuas cov ntsiab lus ntawm ob qho lipids (cov rog thiab cov tshuaj uas zoo ib yam li nws), thiab LDL, tag nrho cov roj cholesterol, ntxiv rau cov ntsiab lus ntawm triglycerides.

Nyob rau hauv rooj plaub thaum thaum ob peb lub hlis cov nyhuv kho tsis pom, tom qab ntawv xaiv lwm txoj kev kho yuav tsum raug txiav txim siab.

Muaj cov hloov rau cov tshuaj Tricor

Fenofibrate Canon (ntsiav tshuaj) Ntsuas: 96 Sab saum toj

Cov analogue yog pheej yig dua los ntawm 424 rubles.

Fenofibrat Canon yog qhov pheej yig dua thiab muaj txiaj ntsig zoo dua analogue ntawm kev lag luam hauv tsev. Kuj tseem muaj nyob hauv cov ntsiav tshuaj thiab muaj cov tib cov tshuaj nquag, tab sis tus nqi yuav pheej yig dua li Tricor. Raws li qhov ntsuas rau kev siv thiab contraindications, tsis muaj qhov sib txawv tseem ceeb ntawm cov tshuaj.

Lipantil 200 M (tsiav tshuaj) Ntsuam Xyuas: 45 Up

Cov analogue yog pheej yig dua los ntawm 69 rubles.

Lipantil 200 M txawv ntawm Tricor hauv daim ntawv tso tawm thiab muag hauv tsiav tshuaj, enteric coated. Cov tshuaj nquag muaj ntsis zoo ib yam, tab sis hauv qhov muab me me loj dua hauv tshuaj ntsiav. Muaj contraindications thiab muaj hnub nyoog txwv, yog li ua ntej pib kev kho mob, peb xav kom koj nyeem cov lus qhia rau kev siv.

Nqe thiab analogues

Tus nqi ntawm Tricor hauv cov khw muag tshuaj tuaj yeem yog 500 thiab txog li 850 rubles, nyob ntawm qhov hnyav (145 lossis 160 mg), kuj tseem nyob ntawm nws cov chaw tsim khoom. Ntxiv mus, tus nqi tiag tiag yuav txawv txav ntawm tus nqi nthuav qhia hauv khw muag tshuaj.

Raws li analogues ntawm Tricor, tshuaj xws li:

Lawv yog cov pheej yig dua Tricor, muaj lawv cov npe ntawm contraindications, nrog rau cov koob tshuaj, uas yuav tsum tau txiav txim los ntawm tus kws kho mob. Yuav ywj pheej rau lawv daim ntawv thov ywj siab.

Tricor: xyuas

Kev txheeb xyuas txog cov tshuaj Tricor feem ntau zoo:

  • Yuri, Lipetsk, 46 xyooCov. Raws li rau qab zib, nws tsis txo nws, thiab Tricor sib ntaus sib tua zoo nrog cov roj (cholesterol). Txawm li cas los xij, kev tswj hwm yog xav tau siv biochemistry,
  • Elena, Belgorod, 38 xyooCov. General mob tau zoo dua. Kuv tau noj tshuaj rau txog ib lub hlis tam sim no, nws zoo li tias kuv tau poob ceeb thawj. Tsis ntev, ntawm qhov xav tau ntawm tus kws kho mob, Kuv yuav raug sim. Kuv tos ntsoov rau lub sijhawm peb lub hlis ntawm kev nkag,
  • Boris, Moscow, hnub nyoog 55 xyoosCov. Kuv haus cov tshuaj Tricor hauv cov chav kawm ntawm 3 hlis. Pib siv hauv kuv qhov teebmeem txhawm rau txo qis triglycerides.

Txhua yam koj xav paub txog Tricor hauv video:

Tricor - ib qho tshuaj rau txo cov roj hauv cov ntshav

Tricor yog ib qho ntawm cov tshuaj lipid-txo qis, tseem hu ua fibrates.

Qhov no lub npe vim yog lub ntsiab active tivthaiv - fenofibrateCov. Nws yog ib qho muab tso tawm ntawm fibroic acid.

Raws li nws cov cawv, cov synthesis ntawm apoprotein CIII raug txo qis, thiab tseem muaj kev txhawb nqa lipoprotein lipase pib, uas txhim kho lipolysis thiab txhawb kev nthuav dav sai ntawm atherogenic lipoproteins los ntawm cov ntshav uas muaj triglycerides.

Kev nqis tes ua ntawm fibroic acid thiab nws cov khoom siv tuaj yeem ua rau PPARa thiab ua kom nrawm rau kev sib txuas ntawm AI thiab AII apoptoreins.

Fenofibrates kuj kho cov catabolism thiab VLDL ntau lawm. Qhov no ua rau kev ntshiab ntawm LDL thiab ib qho kev txo qis hauv kev saib xyuas ntawm nws ntom thiab cov khoom me me.

Koj tuaj yeem nyeem cov kev tshuaj xyuas txog kev siv cov tshuaj no tom kawg ntawm kab lus hauv ntu tshwj xeeb.

Txoj kev ntawm daim ntawv thov

Cov ntsiav tshuaj yog noj ntawm qhov ncauj raws li txhua yam. Lawv yuav tsum tau nqos dej nrog dej ntau.

Nws yog ib qho tsim nyog yuav tau noj cov tshuaj thaum twg los tau, tsis hais noj zaub mov noj rau cov tshuaj nrog cov tshuaj tsis haum ntawm cov khoom nquag ntawm 145 mg. Thaum siv tshuaj nrog qhov ntau dua, yog li, 160 mg, ntsiav tshuaj yuav tsum noj ib txhij nrog zaub mov.

Rau cov neeg laus, ib koob tshuaj 1 ntsiav tshuaj yog tshuaj ib hnub ib zaug. Cov neeg noj Lipantil 200M lossis Tricor 160 tuaj yeem pib siv Tricor 145 txhua lub sijhawm yam tsis tas hloov cov koob tshuaj. Tsis tas hloov cov ntau npaum li cas, tus neeg mob tuaj yeem hloov los ntawm kev noj Lipantil 200M rau Tricor 160.

Neeg laus tib cov tshuaj yog tshuaj raws li ib txwm muaj.

Nrog lub raum lossis lub siab ua haujlwm qhov ntau npaum yog npaj cia ua ntej nrog koj tus kws kho mob.

Tricor teem rau kev siv mus sij hawm ntev yuav tsum noj zaub mov kom nruj, uas tau rau npe ua ntej kev teem caij ntawm cov cuab yeej no. Kev ua tau zoo ntawm nws txoj kev siv tau tuaj yeem ntsuas los ntawm kws kho mob kom kawm txog qhov concentration ntawm lipids hauv cov ntshav cov ntshav. Yog tias cov nyhuv xav tau tsis tshwm sim li ntawm ob peb hlis, tom qab ntawd hloov cov tshuaj kho.

Kev noj tshuaj ntau dhau tsis pom tshwm sim, tab sis yog tias muaj cim tshwm sim, kev kho mob tshwm sim yog qhov tsim nyog.

Siv cov ntsiav tshuaj tsuas yog tom qab sab laj nrog koj tus kws kho mob. Koj yuav tsum tsis txhob thov cov tshuaj ntawm koj tus kheej. Tricor tuaj yeem xaj tau hauv lub hwj tshuaj nkaus xwb.

Tso tawm daim ntawv, muaj pes tsawg leeg

Tricor muaj nyob rau hauv daim ntawv ntawm oblong ntsiav tshuaj, uas yog coated nrog nyias zaj duab xis plhaub ntawm lub teeb dawb xim. Cov ntsiav tshuaj lawv tus kheej tau sau npe nrog cov ntawv sau. Tus lej 145 yog qhia nyob rau ib sab, FOURNIER logo muab tso rau ntawm ob sab.

145 mg tshuaj muaj muag. Cov pob tuaj yeem muaj li ntawm 10 txog 300 daim. Kuj tseem ua ib daim ntawv tso tawm nrog qhov tshuaj ntawm 160 mg ntawm cov tshuaj nquag. Ib pob tuaj yeem muaj li ntawm 10 txog 100 daim. Hauv ib lub thawv ntawv cardboard uas cov tshuaj tsim tawm, muaj 3 lub hlwv nrog ntsiav tshuaj thiab lus qhia.

Hauv tshuaj muaj pes tsawg leeg, cov tshuaj yeeb yam tseem ceeb yog micronized fenofibrate.

Cov khoom siv ntxiv yog:

  • lactose monohydrate,
  • sodium lauryl sulfate,
  • sucrose
  • hypromellose,
  • docusate sodium
  • silica
  • crospovidone
  • magnesium stearate,
  • lauryl sulfate.

Lub plhaub suav nrog Opadry OY-B-28920.

Video: "Atherosclerosis - lub txim ntawm cov cholesterol"

Sab sij huam

Tricorrh muaj qee qhov kev mob tshwm sim, thaum kuaj pom tias nws yog qhov tsim nyog kom thim kev siv cov tshuaj no thiab sab laj nrog kws kho mob.

Tau:Tsawg:
  • dyspeptic tshwm sim
  • siab kev ua si ntawm daim siab enzymes,
  • mob plab
  • cramping thiab cov leeg tsis muaj zog,
  • xeev siab
  • ntuav
  • diffuse myalgia,
  • mob taub hau
  • flatulence
  • zawv plab
  • nce rau hauv cov ntshav concentration ntawm leukocytes thiab hemoglobin,
  • ua pob
  • khaus
  • kev plees kev yi
  • urticaria
  • alopecia
  • cov hlab ntsha sib sib zog nqus thrombosis.
  • mob hlwb
  • nce kev ua haujlwm ntawm CPK,
  • kev ua xua ntawm daim tawv nqaij
  • kab mob siab
  • pancreatitis
  • nce ntshiab transaminase concentration,
  • mob ntsws interstitial,
  • cov tsos ntawm gallstones,
  • kev saib duab
  • mob mob vwm
  • nce rau hauv cov ntshav concentration ntawm urea thiab creatinine,
  • rhabdomyolysis,
  • pulmonary embolism
  • kev saib duab.

Thaum cev xeeb tub

Tricor yog nruj me ntsis contraindicated rau hauv cov poj niam cev xeeb tub thiab cov poj niam thaum lub sijhawm lactation.

Txawm li cas los xij, kev kuaj mob tshawb pom tseeb tias muaj qhov tsis zoo rau tus me nyuam hauv plab tsis tau ua. Txawm li cas los xij, embryotoxicity tau tshwm sim hauv kev teem caij siv tshuaj lom rau lub cev ntawm tus poj niam cev xeeb tub. Txawm hais tias cov tshuaj tsis yog tsim rau cov poj niam cev xeeb tub, hauv qee kis nws raug muab rau cov poj niam nyob rau lub sijhawm no thaum ntsuas qhov piv ntawm cov txiaj ntsig thiab kev pheej hmoo.

Tsis tas li ntawd, qhov tshwm sim ntawm Tricor rau cov menyuam yaus thaum lub sijhawm pub niam mis tsis pom, yog li cov kws kho mob tsis kam muab tshuaj rau lub sijhawm no.

Cov lus thiab cov xwm txheej ntawm kev cia

Tricor yuav tsum muab cia rau hauv chaw tsim khoom ntim. Tsis tas li ntawd, qhov tso cai cia kub yog 25 degrees.

Lub txee lub neej ntawm cov tshuaj yog nyob ntawm qhov kev saib xyuas ntawm cov tshuaj nquag nyob hauv cov tshuaj. Thaum nriav cov ntsiav tshuaj hauv qhov ntau npaum ntawm 145 mg, lawv lub neej txee tuaj yeem ncav cuag 3 xyoos. Thaum siv cov ntsiav tshuaj hauv qhov ntau npaum li 160 mg, lub txee lub neej txo ib xyoos thiab yog 2 xyoos.

Tus nqi ntawm cov tshuaj tsis yog nyob ntawm qhov loj me ntawm pob (qhov ntim ntawm cov ntsiav tshuaj muaj nyob hauv nws) uas nws tsim tawm, tab sis kuj tseem nyob ntawm kev txiav txim siab ntawm cov tshuaj nquag.

Tus nqi nruab nrab hauv Ukraine

Koj tuaj yeem yuav Tricor hauv Ukraine ntawm tus nqi los ntawm 340 txog 400 hryvnias ib pob ntawm cov tshuaj nyob rau hauv ib lub tshuaj ntawm 145 mg (20 ntsiav tshuaj).

Cov tshuaj hauv qab no zwm rau cov yeeb yaj kiab ntawm Traicor:

Kev siv cov analogues tso cai tsuas yog tom qab sab laj tus kws kho mob thiab xaiv cov tshuaj tsim nyog.

Tsis tas li ntawd, cov tshuaj no muaj txhais ua ntau. Nws yog Lipantil 200M, Tshaj, Fenofibrat Canon.

Kev ntsuam xyuas dav dav ntawm cov txiaj ntsig ntawm kev siv Tricor yog cov sib xyaw ntau. Qee tus kws kho mob, thaum sau ntawv yuav siv cov tshuaj no, soj ntsuam qhov pom zoo hauv qhov txo qis thiab kev kho kom zoo ntawm cov lipid profile.

Lwm tus kws kho mob thiab cov neeg mob tau yuam kom tso tseg txoj kev siv tshuaj no, vim tias nws cov kev mob tshwm sim dhau los ntawm qhov tshwm sim zoo ntawm kev siv.

Xijpeem Koj tuaj yeem thov Tricor rau kev kho mob tsuas yog tom qab sab laj nrog koj tus kws kho mob thiab kuaj raum thiab mob siab. Tsuas yog hauv qhov no, yog tias tsis muaj kev pheej hmoo tshawb pom uas ua rau muaj kev cuam tshuam rau hauv tus neeg mob lub cev, nws puas tuaj yeem noj cov tshuaj no.

Kev tshuaj xyuas txog cov tshuaj tsis muaj cov ntaub ntawv hais txog kev hloov pauv ntawm lub neej zoo ntawm tus neeg thaum tsav tsheb.

  • Tricor yog kho rau kev kho mob ntawm hyperlipoproteinemia, uas tsis tuaj yeem kho nrog kev noj haus.
  • Siv cov tshuaj tsuas yog qhia los ntawm tus kws kho mob.
  • Cov tshuaj tag nrho yog siv sab hauv, tsis hais lub sijhawm noj mov (tshwj tsis yog noj cov ntsiav tshuaj hauv 160 mg).
  • Tricor yog contraindicated thaum cev xeeb tub thiab lactation, mob siab thiab lub raum tsis ua hauj lwm, ua rau lub ntsej muag tsis haum rau lub Cheebtsam ntawm cov tshuaj, thiab nws kuj tsis pom zoo rau menyuam yaus.
  • Cov tshuaj muaj pes tsawg tus raug kev mob tshwm sim.
  • Ceev faj yog qhia kom siv Tricor nrog qee yam tshuaj.

Zaj lus puas pab koj? Tej zaum nws yuav pab koj cov phooj ywg thiab! Thov, nyem rau ntawm ib lub nyees khawm:

Hypolipidemic tshuaj Tricor - cov lus qhia rau kev siv

Ib qho ntawm cov tshuaj pabcuam uas siv los kho ntshav qab zib yog Tricor. Nws tsis siv rau cov tshuaj hypoglycemic, tab sis nws tuaj yeem txo qis qis ntawm cov piam thaj hauv cov ntshav.

Txhawm rau kom nkag siab siv nws kom raug, koj yuav tsum nrhiav kom paub thaj chaw tseem ceeb ntawm nws daim ntawv thov thiab cov yam ntxwv tseem ceeb.

Cov ntaub ntawv dav dav, muaj pes tsawg leeg thiab daim ntawv tso tawm

Raws li lub radar, Tricor yog ib hom tshuaj lipid-txo qis - los ntawm cov roj hauv cov ntshav. Nws siv nws pab txo cov roj hauv lub cev thiab tiv thaiv qhov tsim ntawm atherosclerosis.

Nws tso tawm tau tsim tawm hauv Fabkis, qhov chaw uas cov tshuaj no yog muag hauv cov ntsiav tshuaj. Cov nyhuv ntawm cov tshuaj yog vim muaj lub ntsiab tivthaiv, uas yog fenofibrate.

Koj tuaj yeem siv nws tsuas yog tsim los ntawm kws kho mob, vim nws muaj qhov cuam tshuam zoo rau lub cev. Yuav muaj qhov tsis xwm yeem loj yog tias noj yam tsis tsim nyog. Yog li ntawd, nws yog peev xwm yuav nws tsuas yog daim ntawv sau tshuaj.

Kev tsim cov peev nyiaj yog kwv hauv cov ntsiav tshuaj. Lub ntsiab nquag ua haujlwm ntawm cov tshuaj yog fenofibrate. Nws suav nrog cov ntsiav tshuaj hauv qhov ntau npaum li 145 mg.

Ntxiv rau nws, muaj cov khoom siv xws li:

  • sucrose
  • hypromellose,
  • sodium docusate,
  • magnesium stereate,
  • microcrystalline cellulose,
  • lactose monohydrate,
  • sodium laurisulfate,
  • silicon dioxide colloidal.

Cov tshuaj yeeb dej caw no ua rau koj muab tshuaj rau qhov zoo. Cov ntsiav tshuaj yog cov yeeb yaj kiab-coated (bp).

Kuj tseem muaj cov ntsiav tshuaj uas muaj cov ntsiab lus tseem ceeb ntawm 160 mg. Lawv muaj tib lub qub ntxiv uas yog siv lwm yam tshuaj.

Cov ntim ntawm cov tshuaj muaj lub siab sib txawv. Lawv tuaj yeem suav los ntawm 10 txog 300 ntsiav tshuaj (noj ntawm 145 mg) lossis los ntawm 10 txog 100 pieces (koob ntawm 160 mg).

Pharmacological kev txiav txim thiab pharmacokinetics

Txhawm rau kom nkag siab txog yam tshuaj no tau npaj rau, koj yuav tsum nrhiav kom paub cov yam ntxwv ntawm kev nqis tes ua.

Fenofibrate muaj cov nyhuv cuam tshuam nrog triglycerides, txo lawv cov nyiaj. Nws tseem yuav pab txo cov roj hauv cov ntshav. Qhov no yog vim qhov ua txhaum ntawm kev coj ua ke ntawm cov nqaij rog.

Kev siv cov tshuaj tuaj yeem txo cov fibrinogen. Qhov kev ua haujlwm tsis muaj zog me ntsis ua haujlwm ntxiv rau cov kua nplaum, pab ua kom nws qib. Cov haujlwm no ua rau Tricor siv tau los kho cov neeg mob atherosclerosis uas muaj lub siab nyiam mob ntshav qab zib.

Fenofibrate ncav cuag nws cov txiaj ntsig siab tshaj plaws 5 teev tom qab kev tswj hwm (qhov no cuam tshuam los ntawm tus neeg lub cev tus yam ntxwv).

Ib qhov tseem ceeb ntawm nws khi rau albumin, plasma protein, tsim fenofibroic acid. Nws cov metabolism yog nqa tawm hauv lub siab. Cov tshuaj muaj cov nyhuv ua kom ntev ntev - txog 20 teev yuav tsum tau tshem tawm ib nrab ntawm nws. Nws tawm lub cev los ntawm txoj hnyuv thiab raum.

Kev taw qhia thiab contraindications

Koj tuaj yeem paub dab tsi cov cuab yeej no pab tau los ntawm kev kawm cov lus qhia thiab kev qhia rau nws lub hom phiaj.

Nws raug nquahu kom siv nws rau cov kev ua txhaum cai xws li:

  • hypercholesterolemia,
  • hypertriglyceridemia,
  • hyperlipoproteinemia.

Nrog rau cov kab mob zoo li no, Tricorr siv yog tias txoj kev tsis siv tshuaj kho mob tsis nqa cov txiaj ntsig.

Tsis tas li, tus kws kho mob tuaj yeem sau ntawv yuav muab cov tshuaj no los kov yeej lwm cov kab mob uas yog ib feem ntawm txoj kev kho kom ncaj, yog tias cov kev coj ua tsim nyog.

Nws yuav tsum nco ntsoov tias muaj cov kev taw qhia rau cov tshuaj tsis txhais tau tias yuav tsum tau siv cov tshuaj no. Kev pom ntawm contraindications yuam koj kom tso tseg nws siv.

Cov no suav nrog:

  • mob rau daim siab hnyav
  • mob raum muaj teeb meem
  • intolerance rau lub composition,
  • kev pub mis
  • kab mob gallbladder
  • cov me nyuam muaj hnub nyoog.

Kuj tseem muaj qee kis uas kev siv Tricor raug tso cai, tab sis xav kom muaj kev ceev faj ntxiv:

  • quav cawv
  • hypothyroidism
  • hnub nyoog siab heev
  • ua txhaum nyob rau hauv daim siab thiab lub raum.

Qhov no txhais tau tias koj tuaj yeem noj cov tshuaj no tsuas yog qhia los ntawm cov kws tshwj xeeb. Kev noj tshuaj rau tus kheej tuaj yeem ua rau muaj kev nyuaj.

Cov Neeg Mob Tshwj Xeeb thiab Cov Lus Qhia

Tus naj npawb ntawm cov neeg mob rau leej twg ceev faj tshwj xeeb yog pom zoo thaum siv Tricor yog muaj cov neeg hauv qab no:

  1. Cov poj niam thaum cev xeeb tub. Cov tshuaj nquag ntawm cov tshuaj yog contraindicated, yog li ntawd, nws txoj kev siv yog txwv tsis pub rau lub sijhawm no.
  2. Saib xyuas niam cov txiv. Qhov cuam tshuam ntawm fenofibrate rau kev ua tau zoo ntawm leej niam thiab cov menyuam tsis tau muaj tseeb.Hauv qhov no, cov kws kho mob tsis siv Trikor rau cov neeg mob zoo li no.
  3. Cov menyuam. Cov hnub nyoog qis dua 18 xyoo, cov tshuaj no tsis raug siv, vim nws tsis paub yuav ua li cas nws cov muaj pes tsawg leeg tuaj yeem cuam tshuam rau menyuam lub cev.
  4. Qub neeg. Rau pawg no ntawm tus neeg mob, kev siv cov tshuaj txiav txim siab tuaj yeem lees txais. Tab sis ua ntej nws teem caij, cov neeg mob xav tau kev soj ntsuam kom tsis txhob muaj teeb meem tshwm sim. Dosage txo kuj tseem xyaum.

Lwm tus neeg (hauv qhov tsis muaj contraindications) tuaj yeem siv cov tshuaj raws li kws kho mob tau hais.

Ceev faj yuav tsum tau siv thaum siv Traicor nyob ib puag ncig ntawm kev cuam tshuam hauv qab no ntawm lub cev:

  1. Mob raum. Hauv cov kabmob muaj kabmob hnyav ntawm cov kabmob no, kev siv tshuaj yeeb tshuaj raug txwv. Kev hloov pauv me me nyob rau hauv kev ua haujlwm ntawm lub raum xav tau kev soj ntsuam tas li ntawm chav kawm ntawm txoj kev kho mob nrog nws siv.
  2. Daim siab mob. Txog rau cov teeb meem mob siab me, tus kws kho mob tuaj yeem sau Tricor tom qab tshuaj xyuas. Cov kev ua txhaum hnyav yog qhov laj thawj rau kev tsis kam tshuaj.

Fenofibrate tuaj yeem cuam tshuam kev ua haujlwm ntawm lub siab, yog li txawm tias qhov tsis muaj teeb meem hauv cheeb tsam no, koj yuav tsum tau saib xyuas nws tus mob tsis tseg. Tsis tas li, nyob rau hauv cov tshuaj ntawm yeeb tshuaj, ntshav coagulation tsis tuaj yeem hloov pauv - qhov no kuj yuav tsum tswj tau.

Kev sib cuam tshuam txog Yeeb Tshuaj thiab Analogs

Txoj kev kho kom zoo yog koom nrog kev sib txuam nrog cov tshuaj uas tau siv. Yog tias ib qho kev kho kom tsis ntseeg qhov cuam tshuam ntawm lwm qhov, qhov tshwm sim tuaj yeem tsis pom txog. Yog li, koj yuav tsum xav txog tias Tricor yuav cuam tshuam li cas rau cov tshuaj uas siv nrog nws.

Ceev faj xav tau cov tshuaj no nrog:

  • anticoagulants (fenofibrate nyhav txhim kho lawv cov txiaj ntsig, uas ua rau muaj kev pheej hmoo los ntshav),
  • Cyclosporine (lub raum kev ua haujlwm yuav tuaj tsis zoo),
  • statins (muaj kev phom sij ntawm kev phiv tshuaj rau cov leeg).

Rau lwm yam tshuaj, tsis pom qhov kev hloov loj. Txawm li cas los xij, tus neeg mob yuav tsum qhia tus kws kho mob txog txhua yam tshuaj uas nws siv kom tus kws kho mob tshwj xeeb tau tshaj tawm txog kev kho kom tsim nyog.

Cov laj thawj ntawm kev siv cov cuab yeej analog yuav sib txawv. Ntau zaus, cov neeg mob tab tom nrhiav rau analogues pheej yig dua, vim hais tias noj ib qho tshuaj kim rau ntawm kev tsis tu ncua yog ib qho haujlwm uas tsis kim heev.

Lwm tus txhawj xeeb txog cov kev mob tshwm sim uas ua rau lawv tsis tuaj yeem ua haujlwm. Hauv kev hais txog qhov no, cov kws tshwj xeeb feem ntau yuav tsum xaiv cov tshuaj nrog cov nyhuv zoo sib xws.

Cov no suav nrog:

Qee qhov ntawm cov nyiaj no muaj pes tsawg leeg zoo li Traicor. Rau lwm tus, muaj cov txiaj ntsig zoo sib xws yog yam ntxwv, txawm tias muaj qhov sib txawv hauv cov sib xyaw.

Txhawm rau siv cov analogue, koj yuav tsum sab laj nrog koj tus kws kho mob. Kev noj tshuaj rau yus tus kheej yog ib qho pheej hmoo, yog li koj yuav tsum ua kom ntseeg tau tias cov tshuaj xaiv uas haum rau tus neeg mob tshwj xeeb.

Tus neeg mob lub tswv yim

Kev tshuaj xyuas txog cov tshuaj Tricor feem ntau yog qhov zoo - ntau daim ntawv ceeb toom nws muaj txiaj ntsig zoo rau lub cev thiab txo cov roj cholesterol.

Tus nqi ntawm cov tshuaj yog nyob ntawm seb ntau npaum li cas ntawm cov nquag muaj nyob rau hauv nws thiab tus naj npawb ntawm cov ntsiav tshuaj hauv pob. Txhawm rau pob khoom nrog 30 ntsiav tshuaj (145 mg) koj yuav tsum muab los ntawm 750 txog 900 rubles. Ntawm qhov ntau npaum ntawm 160 mg thiab ntim zoo sib xws, tus nqi rau Tricor yuav yog los ntawm 850 txog 1100 rubles.

Pom zoo Lwm Yam Lus Txog

Tricorrh: cov lus qhia rau kev siv, nqe, xyuas, analogues »

Tricor yog ib qho tshuaj ntawm qhov chaw tsim khoom hauv Fabkis. Raws li cov lus qhia rau kev siv, nws yog npaj rau kev kho mob ntawm pathologies ntawm cov hlab plawv system.

Nws zwm rau cov pab pawg ntawm lipid-txo cov tshuaj, tseem hu ua fibrates. Lub npe no qhia nws cov khoom siv tiv thaiv - fenofibrate.

Cov tshuaj yog hais txog kev derivatives muab los ntawm fibroic acid.

Thov

Hauv kev kho mob, Tricor tau siv los kho cov kab mob hauv qab no:

  • hypercholesterolemia thiab hypertriglyceridemia, ob leeg cais thiab sib xyaw (sib txawv ntawm dyslipidemia) hauv cov neeg mob rau cov neeg noj zaub mov ua rau tsis muaj txiaj ntsig, lossis lwm txoj kev siv tshuaj uas tsis siv tshuaj (kev ntsuas tsom poob phaus, nce lub cev kev ua si). Qhov no tseem ceeb heev rau qee qhov xwm txheej uas muaj kev pheej hmoo tsis zoo xws li kev coj tsis zoo (haus luam yeeb) thiab kub siab,
  • secondary hyperlipoproteinemia thaum nws cov tsos mob mob siab txawm hais tias muaj txiaj ntsig ntawm kev kho rau qhov mob tseem ceeb (piv txwv li, dyslipidemia nyob rau hauv ntshav qab zib mellitus).

Tso Tawm Cov Ntawv

Hauv kev tsim tshuaj, cov tshuaj muaj nyob hauv daim ntawv ntawm ob hom ntsiav tshuaj, sib txawv hauv qhov ntim ntawm cov tshuaj nquag (fenofibrate), uas muaj nyob hauv qhov ntim ntawm 145 mg (micronized), lossis 160 mg.

Cov tsos mob yog sucrose, sodium lauryl sulfate, lactose monohydrate, crospovidone, colloidal silicon dioxide, thiab lwm yam.

Cov ntsiav tshuaj muaj lub ntsej muag oblong, lawv tau them nrog ib txheej yeeb yaj kiab dawb. Lub logo tau kos rau ntawm ib sab, thiab tus lej ntawm sab tod qhia qhov nyiaj ntawm cov khoom tseem ceeb hauv cov khoom muaj pes tsawg leeg (145 lossis 160).

Cov ntsiav tshuaj muab tso rau hauv lub hlwv ntawm 10 daim. Ib pob ntawv cardboard tuaj yeem ntim ntawm 1 txog 10 hlwv.

Kev nplua

Kev siv Tricor nrog hypoglycemic cov neeg ua hauj lwm ib txhij uas yog derivatives ntawm sulfonylureas tuaj yeem ua rau nce ntxiv hauv cov nyhuv hypoglycemic.

Kev sib xyaw ntawm Tricor nrog indirect anticoagulants (suav nrog acenocoumarol, warfarin) txhim kho qhov cuam tshuam rau tom kawg.

Muaj ib qho kev xav tau hais txog lub luag haujlwm tseem ceeb ntawm cov fibrates hauv kev nce qib kev sib raug zoo ntawm anticoagulants rau qee cov receptors, ntxiv rau kev ua txhaum ntawm lawv cov txheej txheem hauv metabolic.

Kev sib xyaw ua ke ntawm cov tshuaj no nrog cyclosporine tuaj yeem ua rau lub raum ua haujlwm tsis zoo thiab nce ntxiv ntawm cov tshuaj no hauv cov ntshav.

Noj ntau dhau

Cov cim ntawm tus cwj pwm tsis txaus noj thaum noj Traicor tsis tau piav qhia los ntawm ntaub ntawv kho mob. Tsis tas li, muaj cov tshuaj tiv thaiv kev tiv thaiv tshwj xeeb tsis tau tsim. Yog tias muaj kev ua xyem xyav ntawm kev huaj cheej, tsos mob thiab, yog tias tsim nyog, kev kho tu yuav tsum kho. Nws tau txiav txim siab tias hemodialysis siv tsis tau.

Nina P. hauv kev tshuaj xyuas http://otzovik.com/review_2302884.html qhia txog qhov ua tau ntawm cov tshuaj, tshwj xeeb nws qhov tseem ceeb rau txo cov roj (cholesterol).

Txawm li cas los xij, nws ceeb toom rau kev tiv thaiv tus kheej, hais txog qhov yuav tsum tau soj ntsuam tas li ntawm cov kws tshwj xeeb thaum kho mob. Tus neeg sau kuj tseem taw qhia txog qhov ua tau rau muaj kev mob tshwm sim loj thaum lub sij hawm kho nrog Tricor.

Yog li nws tus kheej nws tau tsim muaj cov mob qog. Vim li no, tus poj niam tsis kam yauv yauv mus ua txoj haujlwm thib ob thiab txiav txim siab tias nws yuav tsum tau xaj kom tiav ntu ultrasound ntawm txoj hnyuv.

Cov tshuaj tau yuav khoom nruj me ntsis raws li kws kho mob tau sau tseg los ntawm tus kws kho mob uas ib txwm soj ntsuam cov kev kuaj mob txhawm rau paub tseeb tias tsis muaj kev phiv.

Elena K. hauv kev tshuaj xyuas https://health.mail.ru/drug/tricor/ sau tias cov tshuaj no tsis haum rau nws. Nws haus nws ob lub hlis thiab hnov ​​mob hnyav hauv lub paresis ntawm lub cev, li no cov leeg tsis muaj zog. Nws kuj tsis pom kev txhim kho, rau qhov laj thawj no nws tsis pom zoo kom Tricor siv.

Alexey P. hauv kev tshuaj xyuas https://health.mail.ru/drug/tricor/ sau hais tias nws tau coj Tricor ntau dua 4 lub hlis. Nyob rau lub sijhawm no, mob ntawm cov ceg txo qis, thiab kev noj qab haus huv tau zoo dua.

Tricor yog ib hom tshuaj ua nyob rau hauv Fabkis. Siv nyob rau hauv kev kho mob ntawm cov kab mob ntawm cov hlab plawv system. Raws li tus neeg sawv cev lipid-txo qis, Tricor belongs rau cov fibrates.

Nws siv ncaj qha rau nws lub hom phiaj raws li cov lus qhia, ntawm kev pom zoo thiab hauv kev saib xyuas ntawm tus kws kho mob. Muaj ib tug xov tooj ntawm contraindications thiab phiv. Thaum noj cov tshuaj no, kev saib xyuas yuav tsum tau noj thiab cov koob tshuaj tau qhia.

Tsis haum rau cov poj niam cev xeeb tub thiab pub mis, nrog rau menyuam yaus.

Txuag lossis sib qhia:

Tricor: analogues tsuas yog pheej yig dua, cov lus qhia rau kev siv, tus nqi, tshuaj xyuas

Tricor- Cov tshuaj no yog siv rau cov ntshav qab zib thiab dyslipidemia. Nws muaj cov yam ntxwv hypolipidemic yam ntxwv.

Mechanism ntawm kev ua:

  • Nws ua kom RAPP-alpha, uas ua rau kom muaj zog ntawm lipolysis,
  • Tsim cov apoproteins ntawm hom AI, AII,
  • Txo cov tshuaj concentration ntawm atherogenic lipids hauv plasma vim muaj qhov ua haujlwm nce ntxiv,
  • Txo cov roj (cholesterol) tag nrho, triglycerides,
  • Ua rau cov roj (cholesterol) seem txo qis,
  • Tiv thaiv platelet kev sib xyaw cuam tshuam nrog epinephrine, arachidonic acid thiab ADP.

Hais txog cov ntsiav tshuaj pheej yig los txo cov roj cholesterol - cov npe, cov nqi thiab tshuaj xyuas peb tau sau ntawm no.

Ib qho tseem ceeb ntawm cov tshuaj yog tias nyob rau hauv tib neeg lub cev circulatory theem ntawm fenofibrate mus txog qhov siab tshaj plaws, cov nyhuv no pom tau tam sim no 2-3 teev tom qab noj tshuaj. Cov cuab yeej tseem muaj cov nyhuv uricosuric.

Pheej yig analogues ntawm Tricor

  • Fenofibrat Canon. Nws txawv hauv cov npe ntawm excipients. Cov hmoov txhuv nplej siab pob kws, colloidal silicon dioxide, croscarmellose sodium, mannitol, magnesium stearate, povidone K-30, microcrystalline cellulose siv. Nws yog nqus ntau me ntsis qeeb (tom qab ntawd nws qhov kev siab tshaj plaws hauv cov ntshav tau mus txog). Nqe 489 rub.

  • Tshaj - sib txawv hauv daim ntawv ntawm kev tso tawm (tshuaj ntsiav) thiab cov koob tshuaj ntawm cov tshuaj nquag (fenofibrate) - 250 mg.
  • Tsaus ntuj - sib txawv hauv daim ntawv ntawm kev tso tawm (tshuaj ntsiav), ntau npaum (200 mg). Qhov sib txawv tsuas yog nyob rau hauv cov tshuaj pab - gelatin, hlau oxide (E172), gelatinized hmoov txhuv nplej siab. Tus nqi ntawm 850 rubles.

    Yam tshuaj muaj yeesTshwjxeeb
    Lactose Monohydrate
    Microcrystalline silicatized cellulose
    Crospovidone
    Hypromellose
    Sodium Lauryl Sulfate
    Kev Sodium Docusate
    magnesium stearate
    OpadriOY-B-28920 (Polyvinyl cawv, titanium dioxide (E 171), talc, kua roj lecithin, xanthan ntawm cov pos hniav)

    Muaj nyob rau hauv 145 mg thiab 160 mg ntsiav tshuaj thiab hauv cov pob sib txawv: cov duab los qhia ib pob los ntawm 1 txog 30 hlwv.

    Qhov ncauj anticoagulants

    Exacerbates cov kev cuam tshuam ntawm qhov ncauj tshuaj tiv thaiv, yuav ua rau muaj kev pheej hmoo los ntshav. Txhawm rau kom tsis txhob muaj qhov no, nws raug nquahu kom txo cov koob tshuaj tiv thaiv kab mob los ntawm kwv yees li 1/3 thiab maj mam coj nws ua raws li MHC (cov txheej txheem ib txwm muaj thoob ntiaj teb).

    • Cyclosporin. Ob peb qhov xwm txheej loj ntawm cov hlab ntsws thim rov qab tau raug teev cia. Hauv kev sib txuas nrog cov xwm txheej no, nws yog qhov yuav tsum tau ua tib zoo saib xyuas lub raum kev ua haujlwm hauv cov neeg mob noj cov kev sib xyaw no, thiab thaum muaj kev phom sij hloov hauv chav kuaj ntshav, tam sim ntawd tsum tsis txhob noj Tricor.

    HMG-CoA reductase inhibitors lossis lwm yam ua rau kab mob fibrates

    Txoj kev pheej hmoo ntawm cov tshuaj lom rau ntawm cov leeg, nws yog qhov yuav tsum tau siv xws li kev sib txuas nrog kev ceev faj.

    Thaum noj Traicor nrog cov tshuaj ntawm pab pawg no, muaj qee zaum muaj qhov tsis sib luag ntawm qhov txo qis hauv lipoproteins. Nws yog qhov tsim nyog los tswj lawv qib thiab tam sim ntawd tsum tsis txhob siv qhov sib xyaw no yog tias nws txo qis.

    Cytochrome P450 Enzymes

    Fenofibrates thiab fenofibroic acid tsis yog cov tshuaj tiv thaiv cytochrome isoform (CYP) P450 CYP3A4, CYP2D6, CYP2E1 lossis CYP1A2. Ntawm kev siv tshuaj ntau, lawv yog cov mob me me los sis mob hnyav ntawm CYP2C9 thiab cov tsis muaj zog ntawm CYP2C19 thiab CYP2A6.

    Kev saib xyuas kom zoo ntawm cov neeg mob noj fenofibrate thiab tshuaj uas muaj tshuaj tiv thaiv los ntawm CYP2C19, CYP2A6, thiab tshwj xeeb tshaj yog CYP2C9, thiab tseem muaj qhov ntsuas qis nqaim kho, yog qhov tsim nyog.

  • Cia Koj Saib